{"title":"Effects of Postmortem Intervals on Quantitative MRI in Unfixed and Fixed Swine Brain: Implications for Ex Vivo MRI Applications.","authors":"Lixian Wang, Naoya Oishi, Shin-Ichi Urayama, Takashi Hanakawa","doi":"10.2463/mrms.mp.2025-0159","DOIUrl":"10.2463/mrms.mp.2025-0159","url":null,"abstract":"<p><strong>Purpose: </strong>The postmortem interval (PMI) alters tissue properties that shape quantitative MRI (qMRI) signals. We systematically investigated the effects of PMI on relaxation times, depending on tissue characteristics, in both unfixed and fixed pig brains.</p><p><strong>Methods: </strong>Twelve pig brains (n = 12) were scanned in both unfixed and fixed states at 3 PMI windows (≈12, 24, 48h). Quantitative T1, T2, and T2* maps were acquired with identical protocols at controlled room temperature (~24°C). We assessed the PMI effects on relaxation times in the gray matter (GM) and the white matter (WM) at both group and sample levels, while fixation-induced effects and inter-sample variability were evaluated using pairwise rank correlation and coefficient of variation (CV) visualization.</p><p><strong>Results: </strong>In unfixed tissues, T1 significantly differed among PMI groups in GM (P = 0.0141) and WM (P = 0.0315) in the early window (≤24h). In the same window, PMI-T1 correlations were observed in both GM (r = 0.921, P = 0.007) and WM (r = 0.876, P = 0.013). T2 showed no group differences but exhibited an inverse correlation with PMI in WM (r = -0.849, P = 0.015). No significant PMI-T2* relationships were detected (all P > 0.05). At later PMI (20-50h), PMI-qMRI correlations diminished. Fixation processes altered all qMRI parameters. Notably, the PMI effects on T1 in the unfixed brains were preserved even after fixation at an ordinal level, although fixation introduced substantial inter-sample variability.</p><p><strong>Conclusion: </strong>PMI exerts the most robust effects on T1. Fixation has a significant impact on qMRI values, mitigating the apparent PMI effect and increasing the inter-sample variability. However, it is still possible to retrieve the PMI effects from fixed brain at the level of rank order, providing practical guidance for further ex vivo qMRI studies on PMI.</p>","PeriodicalId":94126,"journal":{"name":"Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13481156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146168432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Value of T1 and T2 Mapping in Diagnosing Chronic Liver Disease-related Kidney Injury and Monitoring the Outcome of Stem Cell Therapy: An Animal Experimental Study.","authors":"Jiaming Qin, Hongtao Yuan, Chao Wang, Yue Wang, Dan Tong, Zhandong Hu, Chen Zhang, Wen Shen, Shuangshuang Xie","doi":"10.2463/mrms.mp.2025-0098","DOIUrl":"10.2463/mrms.mp.2025-0098","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the monitoring value of T1 and T2 mapping in assessing kidney injury associated with chronic liver disease and the therapeutic efficacy of bone marrow mesenchymal stem cells (BMSCs) treatment.</p><p><strong>Methods: </strong>Thirty-six rats were divided into 6 subgroups (n = 6/group) and underwent MRI scanning at 0, 2, 4, 6, 8, and 12 weeks, respectively, followed by biochemical and histological analyses. Seven rats underwent continuous MRI scanning to monitor changes in imaging parameters. Twenty-four rats divided into BMSC and control group. Six rats per group were subjected to serial MRI scans at weeks 13, 14, 15, and 16, another six rats per group were scanned at week 14 and then sacrificed for biochemical and renal histological analysis.</p><p><strong>Results: </strong>From baseline to 12 weeks, renal hematoxylin and eosin (HE) scores and α-smooth muscle actin (α-SMA) levels increased significantly, and similar trends were found in renal T1 and T2 values. Following BMSCs injection, both BMSC and control groups exhibited reductions in HE scores and α-SMA levels, with BMSC group demonstrating more substantial decreases. Renal T1 and T2 values declined in both groups, with the BMSC group showing significantly lower T2 values than the control group. Strong correlations were found between renal T1/T2 values and HE scores, α-SMA levels (|r|=0.419-0.724). The area under the curve values for T1 and T2 in differentiating renal injury severity across different renal strips were from 0.793 to 0.930.</p><p><strong>Conclusion: </strong>T1 and T2 mapping can effectively monitor renal injury progression in chronic liver disease, with T2 values demonstrating greater potential for assessing the therapeutic efficacy of BMSCs.</p>","PeriodicalId":94126,"journal":{"name":"Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13485488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147482845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Letter to the Editor about \"Endometrial Cancer: A Daily Clinical Practice Guide for Radiologists\" Published Online: August 20, 2025.","authors":"Yumiko Oishi Tanaka","doi":"10.2463/mrms.lte.2025-0172","DOIUrl":"10.2463/mrms.lte.2025-0172","url":null,"abstract":"","PeriodicalId":94126,"journal":{"name":"Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13493152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147517921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Visualization of the Trochlear Nerve Using Deep Learning-enhanced 3D T2-weighted MR Imaging at 3T.","authors":"Taiki Koshiishi, Satoru Ide, Yuka Ishimoto, Tomohiro Shintaku, Sera Kasai, Jusei Kudo, Keita Watanabe, Tetsuya Wakayama, Atsushi Nozaki, Xucheng Zhu, Kana Saito, Mizuki Imura, Amo Ozawa, Shuichi Matsuhashi, Tatsuro Sasaki, Saaya Mori, Masashi Matsuzaka, Shingo Kakeda","doi":"10.2463/mrms.mp.2025-0177","DOIUrl":"10.2463/mrms.mp.2025-0177","url":null,"abstract":"<p><strong>Purpose: </strong>Cranial nerve imaging with 3T MRI commonly uses 3D fast imaging employing steady-state acquisition (3D-FIESTA); however, this sequence has limitations in achieving higher spatial resolution and provides poor tissue contrast between cranial nerves and adjacent vascular structures. We evaluated 3D T2-weighted imaging (T2-CUBE) with deep learning-based reconstruction (DLR) for cranial nerve visualization, focusing on the trochlear nerve, the smallest cranial nerve with the longest intracranial course, and compared it with T2-CUBE without DLR and 3D-FIESTA.</p><p><strong>Methods: </strong>Ten healthy male volunteers (age, 23-40 years; mean age, 32 years) underwent T2-CUBE with and without DLR, and 3D-FIESTA at 3T. Two neuroradiologists independently evaluated trochlear nerve visualization in 4 anatomical segments (origin from the midbrain, cisternal, tentorial, and anterior portion of its cavernous segments) using a 3-point scale, and SNR of the pons (SNR<sub>PONS</sub>) and cerebrospinal fluid (SNR<sub>CSF</sub>) were calculated.</p><p><strong>Results: </strong>T2-CUBE with DLR achieved a 100% visualization across all trochlear nerve segments and demonstrated significantly better visualization than both T2-CUBE without DLR and 3D-FIESTA (P < 0.025). T2-CUBE without DLR showed 67.5%-100% visualization across the 4 segments. 3D-FIESTA showed 32.5%-80% visualization of the origin from the midbrain, cisternal, and tentorial segments, with no visualization of the cavernous segments. DLR increased SNR<sub>PONS</sub> and SNR<sub>CSF</sub> by factors of 1.8-2.5 (SNR<sub>PONS</sub>: 14.1 vs 5.7; SNR<sub>CSF</sub>: 31.8 vs 17.5, respectively; P < 0.001). T2-CUBE with DLR demonstrated significantly higher SNR<sub>PONS</sub> than 3D-FIESTA (14.1 vs 6.4, P < 0.001), while SNR<sub>CSF</sub> was comparable (31.8 vs 36.3, P = 0.20).</p><p><strong>Conclusion: </strong>T2-CUBE with DLR at 3T provided a significantly better trochlear nerve visualization than T2-CUBE without DLR and 3D-FIESTA. This technique may extend beyond the trochlear nerve to other cranial nerves and to the evaluation of neurovascular compression in the cistern, with the potential to become the new standard for cisternal imaging.</p>","PeriodicalId":94126,"journal":{"name":"Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13485384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147482843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparing the Perfusion and Functional Assessment Capabilities of Electrocardiography- and Photoplethysmography-monitored Phase-resolved Functional Lung and Dynamic Contrast-enhanced Perfusion MR Imaging.","authors":"Yoshiyuki Ozawa, Alicia Palomar-García, Masanori Ozaki, Masao Yui, Maiko Shinohara, Natsuka Yazawa, Kaori Yamamoto, Yuichiro Sano, Masato Ikedo, Takahiro Ueda, Masahiko Nomura, Takeshi Yoshikawa, Daisuke Takenaka, Yoshiharu Ohno","doi":"10.2463/mrms.mp.2025-0201","DOIUrl":"10.2463/mrms.mp.2025-0201","url":null,"abstract":"<p><strong>Purpose: </strong>The present study directly compared the quantitative capabilities of regional perfusion and pulmonary functional change assessments among electrocardiography (ECG)- and photoplethysmography (PPG)-monitored phase-resolved functional lung (PREFUL) MRI and dynamic contrast-enhanced (CE) perfusion MRI in thoracic oncologic patients.</p><p><strong>Methods: </strong>Seventeen thoracic oncologic patients prospectively underwent ECG- and PPG-monitored PREFUL MRI, dynamic CE-perfusion MRI, and pulmonary function tests. ECG- and PPG-monitored perfusion-weighted PREFUL MRI (PW-MRI) and quantitative perfusion maps from dynamic CE-perfusion MRI were generated. Regional perfusions were determined using ROI measurements. For each patient, the overall perfusion from each method was determined as the average ROI measurement value. To determine the relationship between regional perfusion among all methods, Pearson's correlations were performed. Tukey's honest significant difference test was performed to compare regional perfusion among ventral, middle, and dorsal slice positions on ECG- and PPG-monitored PW-MRI and quantitative perfusion maps. To assess the pulmonary functional loss evaluation capability of each MRI method, each overall perfusion was correlated with %VC and %FEV<sub>1</sub> using Pearson's correlation.</p><p><strong>Results: </strong>The correlation of regional perfusion between ECG- and PPG-monitored PW-MRI was significant and good (r = 0.79, P < 0.0001). However, the correlations between ECG- or PPG-monitored PW-MRI and quantitative perfusion maps were assessed as significant and fair (ECG: r = 0.4, P < 0.0001; PPG: r = 0.36, P < 0.0001). ECG- and PPG-monitored PW-MRI demonstrated significantly higher perfusion than the quantitative perfusion map (P < 0.0001). Furthermore, ECG-and PPG-monitored PW-MRI and quantitative perfusion maps had significant and moderate correlations (%VC: 0.60 ≤ r ≤ 0.63, P < 0.05; %FEV<sub>1</sub>: 0.52 ≤ r ≤ 0.69, P < 0.05).</p><p><strong>Conclusion: </strong>ECG- and PPG-monitored PREFUL MRI had similar potential to dynamic CE-perfusion MRI for quantitatively assessing regional perfusion and pulmonary functional changes in thoracic oncologic patients. Furthermore, PPG-monitored PREFUL MRI showed little difference in regional perfusion evaluation compared with ECG-monitored PREFUL MRI and the potential to play a complementary role in this setting.</p>","PeriodicalId":94126,"journal":{"name":"Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13489979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147679119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fadime Güven, Muhammed Halid Yener, Muhammed Emre Işıktaş
{"title":"Calcification Detection versus Lesion Characterization in Breast SWI: Clinical Experiences with Standard Protocols.","authors":"Fadime Güven, Muhammed Halid Yener, Muhammed Emre Işıktaş","doi":"10.2463/mrms.lte.2025-0191","DOIUrl":"10.2463/mrms.lte.2025-0191","url":null,"abstract":"","PeriodicalId":94126,"journal":{"name":"Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13493151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147482856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Respiratory-gating Reduces Motion Artifacts Due to Uterine Displacement in T2-weighted MR Imaging of the Female Pelvis.","authors":"Hironobu Ishikawa, Masahiko Monma, Yoshiyuki Ishimori, Kousaku Saotome, Shiro Ishii, Hirofumi Sekino, Ryo Yamakuni, Takeyasu Kakamu, Daisuke Oura, Yuma Takahashi, Shinya Seino, Masanori Yusa, Hiroshi Ito","doi":"10.2463/mrms.mp.2025-0065","DOIUrl":"10.2463/mrms.mp.2025-0065","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess the potential enhancement of image quality in fast-spin-echo T2-weighted images (FSE-T2WI) with respiratory-gating compared to conventional FSE-T2WI and to clarify how abdominal wall motion affects uterine displacement and consequently impacts image quality.</p><p><strong>Methods: </strong>One hundred and three women who underwent pelvic MRI using a 3T-MRI scanner were enrolled. FSE-T2WI with and without respiratory-gating was visually assessed for motion-related artifacts, and the image quality was categorized as poor, moderate, or excellent. The uterus was classified as type 1 (on the bladder), type 2 (not on the bladder and not retroflexed), or type 3 (uterus contacting the vertebrae or a retroflexed uterus). The relationships (1) between the abdominal wall and uterine displacements, (2) between the quality of FSE-T2WI with and without respiratory-gating and uterine displacement, and (3) between uterine displacement and types were investigated.</p><p><strong>Results: </strong>Respiratory-gated FSE-T2WI achieved better overall image quality, with poor, moderate, and excellent ratings observed in 27, 44, and 32 patients, respectively, compared with 53, 34, and 16 patients for conventional FSE-T2WI. Improvement with respiratory-gating was observed in 43 patients, particularly in those with type 1 and type 2 uteri, whereas only 8 patients showed decreased image quality. A strong correlation was found between abdominal wall and uterine displacements (P < 0.001), indicating that uterine motion is largely driven by respiration. The amplitude of uterine displacement was significantly smaller in type 3 uteri (P < 0.05), consistent with fewer motion-related artifacts.</p><p><strong>Conclusion: </strong>Respiratory-gated FSE-T2WI effectively reduces motion artifacts caused by respiratory-induced uterine displacement, particularly in type 1 and type 2 uteri where displacement is pronounced.</p>","PeriodicalId":94126,"journal":{"name":"Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13485487/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147380299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Diagnostic Potential of Macromolecular Proton Fraction Mapping Combined with Quantitative Susceptibility Mapping as a Subcortical Biomarker for Parkinson's Disease\" by Fujiwara et al.","authors":"Rohma Zubairi","doi":"10.2463/mrms.lte.2025-0176","DOIUrl":"10.2463/mrms.lte.2025-0176","url":null,"abstract":"","PeriodicalId":94126,"journal":{"name":"Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13487517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146121500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Fast and Precise Method to Search for Desirable Rectangular Tumor Regions in Brain MR Images.","authors":"Hidenori Takeshima, Shuki Maruyama","doi":"10.2463/mrms.mp.2025-0156","DOIUrl":"10.2463/mrms.mp.2025-0156","url":null,"abstract":"<p><strong>Purpose: </strong>To develop a fast and precise method for searching rectangular regions in brain tumor images.</p><p><strong>Methods: </strong>The authors propose a new method for searching rectangular tumor regions in brain MR images. The proposed method consisted of a segmentation network and a fast search method with a user-controllable search metric. As the segmentation network, the U-Net whose encoder was replaced by the EfficientNet was used. In the fast search method, summed-area tables were used for accelerating sums of voxels in rectangular regions. Use of the summed-area tables enabled exhaustive search of the 3D offset (3D full search). The search metric was designed for giving priority to nearly isotropic rectangles over undesirable thin rectangles, and assigning better values for higher tumor fractions even if they exceeded target tumor fractions. The proposed computation and metric were compared with those used in a conventional method using the Brain Tumor Image Segmentation dataset.</p><p><strong>Results: </strong>When the 3D full search was used, the proposed computation (8 seconds) was 100-500 times faster than the conventional computation (11-40 minutes). When the user-controllable parts of the search metrics were changed variously, the tumor fractions of the proposed metric were higher than those of the conventional metric. In addition, the conventional metric preferred undesirable thin rectangles whereas the proposed metric preferred nearly isotropic rectangles.</p><p><strong>Conclusion: </strong>The proposed method is promising for implementing fast and precise search of rectangular tumor regions, which is useful for brain tumor diagnosis using MRI systems. The proposed computation reduced processing times of the 3D full search, and the proposed metric improved the quality of the assigned rectangular tumor regions.</p>","PeriodicalId":94126,"journal":{"name":"Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13280205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145919486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Blood Flow Energy Loss before and after Endovascular Aneurysm Repair Using Four-dimensional Flow MR Imaging.","authors":"Shimpei Ikeda, Takahiko Mine, Tetsuro Sekine, Masashi Abe, Hirotaka Ito, Ko Okada, Seigoh Happoh, So Ueshima, Takahiro Tomoda, Masahiro Fujii, Hiromitsu Hayashi, Shin-Ichiro Kumita","doi":"10.2463/mrms.mp.2025-0031","DOIUrl":"10.2463/mrms.mp.2025-0031","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate hemodynamic changes associated with aortic stiffness after endovascular aneurysm repair (EVAR) for abdominal aortic aneurysm using 4-dimensional flow MRI (4D Flow MRI), with a focus on blood flow energy loss (EL).</p><p><strong>Methods: </strong>Thirty-five patients underwent 4D Flow MRI before and after EVAR. Flow velocity, volume, and reflux ratio were measured at the juxtarenal aorta, aneurysmal orifice, and distal iliac landing zone. EL was assessed at the neck and treatment segments, and its relationship with pulse wave velocity (PWV) was analyzed.</p><p><strong>Results: </strong>Post-EVAR velocity and volume increased across all segments, whereas reflux ratio decreased at the aneurysmal orifice. EL significantly increased at the neck (6.3 [4.0-9.7] vs 16.7 [5.4-29.9] mW, P < 0.001) and treatment segments (29.0 [21.8-45.2] vs 265.6 [182.7-443.6] mW, P < 0.001). Patients with increased PWV showed a greater EL rise at the neck (6.8 [4.2-11.5] vs 16.9 [7.9-30.4] mW, P = 0.001). When stratified by pre-EVAR brachial-ankle PWV, the high-risk group (≥ 1800 cm/s) had a higher post-/pre-EL ratio (6.7 [4.0-10.6] vs 10.4 [7.0-15.8], P = 0.018).</p><p><strong>Conclusion: </strong>EVAR induces specific hemodynamic alterations. The post-operative rise in flow velocity, volume, and EL indicates increased aortic stiffness, suggesting elevated cardiac afterload in patients with advanced arterial stiffness.</p>","PeriodicalId":94126,"journal":{"name":"Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine","volume":"25 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13287559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147577464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}