Journal of hazardous materials最新文献_第8页

Exploring alkali-treated corn cob for high-rate removal of NO_X and SO₂ from flue gas: Focus on carbon release capacity, removal performance, and comparison with conventional carbon sources. 探索碱处理玉米芯对烟道气中 NOX 和 SO2 的高去除率：重点关注碳释放能力、去除性能以及与传统碳源的比较。

Journal of hazardous materials Pub Date : 2024-10-05 Epub Date: 2024-08-22 DOI: 10.1016/j.jhazmat.2024.135613

Yao Lu, Biaojun Zhang, Ying Cao, Yanling Wang, Yongqing Zhang, Shaobin Huang

{"title":"Exploring alkali-treated corn cob for high-rate removal of NOX and SO2 from flue gas: Focus on carbon release capacity, removal performance, and comparison with conventional carbon sources.","authors":"Yao Lu, Biaojun Zhang, Ying Cao, Yanling Wang, Yongqing Zhang, Shaobin Huang","doi":"10.1016/j.jhazmat.2024.135613","DOIUrl":"10.1016/j.jhazmat.2024.135613","url":null,"abstract":"This investigation explored the potential of utilizing alkali-treated corn cob (CC) as a solid carbon source to improve NOX and SO2 removal from flue gas. Leaching experiments unveiled a hierarchy of chemical oxygen demand release capacity: 0.03 mol/L alkali-treated CC > 0.02 mol/L > 0.01 mol/L > 0.005 mol/L > control. In NOX and SO2 removal experiments, as the inlet NOX concentration rose from 300 to 1000 mg/m3, the average NOX removal efficiency increased from 58.56 % to 80.00 %. Conversely, SO2 removal efficiency decreased from 99.96 % to 91.05 %, but swiftly rebounded to 98.56 % by day 18. The accumulation of N intermediates (NH4+, NO3-, NO2-) increased with escalating inlet NOX concentration, while the accumulation of S intermediates (SO42-, SO32-, S0) varied based on shifts in the population of functional bacteria. The elevation in inlet NOX concentration stimulated the growth of denitrifying bacteria, enhancing NOX removal efficiency. Concurrently, the population of nitrate-reducing sulfur-oxidizing bacteria and sulfate-reducing bacteria expanded, aiding in the accumulation of S0 and the removal of SO2. The comparison experiments on carbon sources confirmed the comparable NOX and SO2 removal efficiencies of alkali-treated CC and glucose, yet underscored differences in intermediates accumulation due to distinct genus structures.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"478 ","pages":"135613"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of sanguinarine as a novel antagonist for perfluorooctanoate/perfluorooctane sulfonate-induced senescence of hepatocytes: An integrated computational and experimental analysis. 鉴定番荔枝碱为全氟辛酸/全氟辛烷磺酸诱导肝细胞衰老的新型拮抗剂：计算与实验综合分析

Journal of hazardous materials Pub Date : 2024-10-05 Epub Date: 2024-08-22 DOI: 10.1016/j.jhazmat.2024.135583

Xue Zhang, Huan Gao, Xiaoyu Chen, Ziqi Liu, Han Wang, Mengxing Cui, Yajie Li, Yongjiang Yu, Shen Chen, Xiumei Xing, Liping Chen, Daochuan Li, Xiaowen Zeng, Qing Wang

{"title":"Identification of sanguinarine as a novel antagonist for perfluorooctanoate/perfluorooctane sulfonate-induced senescence of hepatocytes: An integrated computational and experimental analysis.","authors":"Xue Zhang, Huan Gao, Xiaoyu Chen, Ziqi Liu, Han Wang, Mengxing Cui, Yajie Li, Yongjiang Yu, Shen Chen, Xiumei Xing, Liping Chen, Daochuan Li, Xiaowen Zeng, Qing Wang","doi":"10.1016/j.jhazmat.2024.135583","DOIUrl":"10.1016/j.jhazmat.2024.135583","url":null,"abstract":"Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS), two prominent per- and polyfluoroalkyl substances (PFASs), are potentially harmful to many human organs. However, there only exist limited methods to mitigate their health hazards. The aim of this study is to combine a bioinformatics analysis with in vitro experiments to discover small molecules that can alleviate liver damage caused by PFOA/PFOS. We identified 192 and 82 key genes related to hepatocytes exposed to PFOA and PFOS, respectively. The functional enrichment analysis of key genes suggested cellular senescence may be important in PFOA/PFOS-induced hepatotoxicity. The in vitro models revealed that PFOA/PFOS led to hepatocyte senescence by increasing the activity of SA-β-gal, inducing mitochondrial dysfunction, impacting cell cycle arrest, and elevating the expressions of p21, p53, IL-1β, and SASP-related cytokines. The drug-target gene set enrichment analysis method was employed to compare the transcriptome data from the Gene Expression Omnibus database (GEO), Comparative Toxicogenomics Database (CTD), and the high-throughput experiment- and reference-guided database (HERB), and 21 traditional Chinese medicines (TCMs) were identified that may alleviate PFOA/PFOS-induced liver aging. The experimental results of co-exposure to PFOA/PFOS and TCMs showed that sanguinarine has particular promise in alleviating cellular senescence caused by PFOA/PFOS. Further investigations revealed that the mTOR-p53 signaling pathway was involved in PFOA/PFOS-mediated hepatic senescence and can be blocked using sanguinarine.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"478 ","pages":"135583"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular imprinting electrochemical sensor based on hollow spherical PProDOT-2CH₂OH and chitosan-derived carbon materials for highly sensitive detection of chloramphenicol. 基于中空球形 PProDOT-2CH2OH 和壳聚糖衍生碳材料的分子印迹电化学传感器，用于高灵敏度检测氯霉素。

Journal of hazardous materials Pub Date : 2024-10-05 Epub Date: 2024-08-22 DOI: 10.1016/j.jhazmat.2024.135615

Qian Cheng, Cong Xue, Tursun Abdiryim, Ruxangul Jamal

{"title":"Molecular imprinting electrochemical sensor based on hollow spherical PProDOT-2CH2OH and chitosan-derived carbon materials for highly sensitive detection of chloramphenicol.","authors":"Qian Cheng, Cong Xue, Tursun Abdiryim, Ruxangul Jamal","doi":"10.1016/j.jhazmat.2024.135615","DOIUrl":"10.1016/j.jhazmat.2024.135615","url":null,"abstract":"The misuse of chloramphenicol (CAP) has jeopardized environmental safety. It is critical to create an effective and sensitive CAP detection technique. In this paper, a composite of chitosan (CS)-derived carbon material modified hollow spherical hydroxylated poly(3,4-propylenedioxythiophene) (PProDOT-2CH2OH) was designed, which innovatively used o-phenylenediamine and p-aminobenzoic acid as bi-functional monomers to prepare molecular imprinting polymer (MIP) sensors for highly sensitive analysis and determination of CAP. It was found that the hollow spherical structure of PProDOT-2CH2OH significantly enhanced the rapid electron migration. When combined with the CS-derived carbon material, which has multi-functional sites, it improved the electrical activity and stability of the sensor. It also provided more active centers for the MIP layer to specifically recognize CAP. Therefore, this MIP sensor had a wide linear response (0.0001 ∼ 125 μM), a low limit of detection (LOD, 6.6 pM), excellent selectivity and stability. In addition, studies showed that the sensor has potential practical value. ENVIRONMENTAL IMPLICATION: Chloramphenicol (CAP) is one of the most widely used antibiotics with the highest dosage due to its low price and broad-spectrum antimicrobial properties. Due to its incomplete metabolism in living organisms and its difficulty in degrading in the environment, contamination caused by it can pose a threat to public health. In this study, a novel molecularly imprinted sensor (MIP/PC2C1/GCE) was designed to provide a new idea for rapid and precise removal of CAP by adsorption. The detection of CAP in pharmaceutical, water quality, and food fields was realized.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"478 ","pages":"135615"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conditionally restricted detection of nitrite under acidic conditions by activatable fluorescent probes. 利用可激活的荧光探针有条件限制地检测酸性条件下的亚硝酸盐。

Journal of hazardous materials Pub Date : 2024-10-05 Epub Date: 2024-08-16 DOI: 10.1016/j.jhazmat.2024.135495

Xiang Wang, Yu Guo, Long Zhao, Yuqin Yang, Peng Wei, Tao Yi

引用次数: 0

Efficient degradation and mineralization of polyethylene terephthalate microplastics by the synergy of sulfate and hydroxyl radicals in a heterogeneous electro-Fenton-activated persulfate oxidation system. 在异质电-芬顿激活的过硫酸盐氧化系统中，硫酸根和羟基自由基的协同作用可高效降解聚对苯二甲酸乙二酯微塑料并使其矿化。

Journal of hazardous materials Pub Date : 2024-10-05 Epub Date: 2024-08-24 DOI: 10.1016/j.jhazmat.2024.135635

Yinghui Lin, Yuehua Zhang, Yonghao Wang, Yuancai Lv, Linyan Yang, Zhijie Chen, Bing-Jie Ni, Xueming Chen

{"title":"Efficient degradation and mineralization of polyethylene terephthalate microplastics by the synergy of sulfate and hydroxyl radicals in a heterogeneous electro-Fenton-activated persulfate oxidation system.","authors":"Yinghui Lin, Yuehua Zhang, Yonghao Wang, Yuancai Lv, Linyan Yang, Zhijie Chen, Bing-Jie Ni, Xueming Chen","doi":"10.1016/j.jhazmat.2024.135635","DOIUrl":"10.1016/j.jhazmat.2024.135635","url":null,"abstract":"The presence of polyethylene terephthalate (PET) microplastics (MPs) in waters has posed considerable threats to the environment and humans. In this work, a heterogeneous electro-Fenton-activated persulfate oxidation system with the FeS2-modified carbon felt as the cathode (abbreviated as EF-SR) was proposed for the efficient degradation of PET MPs. The results showed that i) the EF-SR system removed 91.3 ± 0.9 % of 100 mg/L PET after 12 h at the expense of trace loss (< 0.07 %) of [Fe] and that ii) dissolved organics and nanoplastics were first formed and accumulated and then quickly consumed in the EF-SR system. In addition to the destruction of the surface morphology, considerable changes in the surface structure of PET were noted after EF-SR treatment. On top of the emergence of the O-H bond, the ratio of C-O/C=O to C-C increased from 0.25 to 0.35, proving the rupture of the backbone of PET and the formation of oxygen-containing groups on the PET surface. With the verified involvement and contributions of SO4•- and •OH, three possible paths were proposed to describe the degradation of PET towards complete mineralization through chain cleavage and oxidation in the EF-SR system.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"478 ","pages":"135635"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The integration of omics and cultivation-dependent methods could effectively determine the biological risks associated with the utilization of soil conditioners in agriculture. 将全息图学和依赖于栽培的方法结合起来，可以有效地确定与农业中使用土壤改良剂相关的生物风险。

Journal of hazardous materials Pub Date : 2024-10-05 Epub Date: 2024-08-23 DOI: 10.1016/j.jhazmat.2024.135567

Arianna Peruzzo, Sara Petrin, Aurora Boscolo Anzoletti, Marzia Mancin, Andrea Di Cesare, Raffaella Sabatino, Maria Cristina Lavagnolo, Giovanni Beggio, Giulia Baggio, Patrizia Danesi, Lisa Barco, Carmen Losasso

{"title":"The integration of omics and cultivation-dependent methods could effectively determine the biological risks associated with the utilization of soil conditioners in agriculture.","authors":"Arianna Peruzzo, Sara Petrin, Aurora Boscolo Anzoletti, Marzia Mancin, Andrea Di Cesare, Raffaella Sabatino, Maria Cristina Lavagnolo, Giovanni Beggio, Giulia Baggio, Patrizia Danesi, Lisa Barco, Carmen Losasso","doi":"10.1016/j.jhazmat.2024.135567","DOIUrl":"10.1016/j.jhazmat.2024.135567","url":null,"abstract":"In the circular economy, reusing agricultural residues, treated biowaste, and sewage sludges-commonly referred to as soil conditioners-in agriculture is essential for converting waste into valuable resources. However, these materials can also contribute to the spread of antimicrobial-resistant pathogens in treated soils. In this study, we analyzed different soil conditioners categorized into five groups: compost from source-separated biowaste and green waste, agro-industrial digestate, digestate from anaerobic digestion of source-separated biowaste, compost from biowaste digestate, and sludges from wastewater treatment plants. Under Italian law, only the first two categories are approved for agricultural use, despite Regulation 1009/2019/EU allowing the use of digestate from anaerobic digestion of source-separated biowaste in CE-marked fertilizers. We examined the bacterial community and associated resistome of each sample using metagenomic approaches. Additionally, we detected and isolated various pathogens to provide a comprehensive understanding of the potential risks associated with sludge application in agriculture. The compost samples exhibited higher bacterial diversity and a greater abundance of potentially pathogenic bacteria compared to other samples, except for wastewater treatment plant sludges, which had the highest frequency of Salmonella isolation and resistome diversity. Our findings suggest integrating omics and cultivation-dependent methods to accurately assess the biological risks of using sludge in agriculture.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"478 ","pages":"135567"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disentangling external loadings, hydrodynamics and biogeochemical controls on the fate of nitrate in a coastal embayment. 厘清外部负荷、流体力学和生物地球化学对沿岸海湾硝酸盐归宿的控制。

Journal of hazardous materials Pub Date : 2024-10-05 Epub Date: 2024-08-15 DOI: 10.1016/j.jhazmat.2024.135465

Wenzhao Liang, Xin Luo, Yi Liu, Jiu Jimmy Jiao, Meiqing Lu, Zhenwei Yan, Xingxing Kuang

{"title":"Disentangling external loadings, hydrodynamics and biogeochemical controls on the fate of nitrate in a coastal embayment.","authors":"Wenzhao Liang, Xin Luo, Yi Liu, Jiu Jimmy Jiao, Meiqing Lu, Zhenwei Yan, Xingxing Kuang","doi":"10.1016/j.jhazmat.2024.135465","DOIUrl":"10.1016/j.jhazmat.2024.135465","url":null,"abstract":"Nitrogen, as an essential nutrient, largely contributes to the coastal eutrophication. However, the accurate depiction and evaluation of how external loadings, hydrodynamics, and biogeochemical reactions mediate the occurrence, transport, and transformation of nitrate (NO3-) within coastal embayment still pose ongoing challenges to date. In this study, we took advantage of dual isotopes of NO3- to track external NO3- loadings, radium and dual isotopes of H2O to characterize the influences of hydrodynamic on NO3- transport, δ18O-NO3- and δ18O-H2O along with microbial analysis to explore major NO3- biogeochemical reactions in Tolo Harbour, Hong Kong. The multiple isotopic evidence showed that NO3- in surface harbour water was predominantly contributed by precipitation in wet season and its impact was strengthened by stratification. In dry season, NO3- in the surface harbour water became largely influenced by benthic input and biogeochemical reactions due to intensified vertical mixing. Based on NO3- mass balance model, biogeochemical reaction, especially nitrification, was found to be the major process to secure the closure of NO3- budget and increase NO3- inventory from wet to dry season. Hydrodynamics redistributed the external NO3- loadings and mediated nitrogen biogeochemical reactions, both of which further synergistically regulated the fate of NO3- in the embayment.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"478 ","pages":"135465"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142010136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing variability and hydrochemical characteristics of groundwater fluoride contamination and its associated health risks in East Singhbhum district of Jharkhand, India. 评估印度贾坎德邦东辛格布姆地区地下水氟污染的变异性和水化学特征及其相关健康风险。

Journal of hazardous materials Pub Date : 2024-10-05 Epub Date: 2024-08-15 DOI: 10.1016/j.jhazmat.2024.135498

Balram Ambade, Shrikanta Shankar Sethi, Kalpana Patidar, Sneha Gautam, Mohammed Alshehri

{"title":"Assessing variability and hydrochemical characteristics of groundwater fluoride contamination and its associated health risks in East Singhbhum district of Jharkhand, India.","authors":"Balram Ambade, Shrikanta Shankar Sethi, Kalpana Patidar, Sneha Gautam, Mohammed Alshehri","doi":"10.1016/j.jhazmat.2024.135498","DOIUrl":"10.1016/j.jhazmat.2024.135498","url":null,"abstract":"Groundwater pollution caused by fluoride is a significant concern for the global population owing to its toxicity, which has negative health consequences. Industrial discharges, agricultural practices, and improper waste disposal are primary concerns in evaluating the degree of fluoride contamination in the selected districts of Eastern India. In a targeted area sampling approach, exactly 196 samples were collected during pre- and post-monsoon, and precise fluoride detection was performed using Ion-Selective Electrodes. Fluoride levels in pre-monsoon water were observed within a range of 0.02 to 2.7 mg/L, with an average abundance of 0.4 ± 0.50. In post-monsoon, the concentration ranged from 0.02 to 4.7 mg/L (mean 0.53 ± 0.60). The study found that 97 % of groundwater samples had acceptable fluoride levels within the 1.5 mg/L limit during pre and post-monsoon. Moreover, approximately 87 % of the samples exhibit fluoride content below the 1 mg/L limit. The hazard quotient was observed to be 0.17 to 0.58 in adults, 0.23 to 0.79 in children and 0.36 to 1.26 in infants during pre-monsoon, whereas 0.05 to 0.55 in adults, 0.12 to 0.74 in children and 0.11to 1.19 in infants during post monsoon. The above data indicates that infants had the highest risk of fluoride exposure, with a significant negative correlation between fluoride and calcium ions. Fluoride had minimal to no link with other ions, a modest positive correlation with sulfate, and a weak negative relationship with overall hardness and alkalinity across both seasons. The present study contributes towards the identification of fluoride levels in various areas, making society aware of water contamination and its health impacts.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"478 ","pages":"135498"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142038055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Benchmarking produced water treatment strategies for non-toxic effluents: Integrating thermal distillation with granular activated carbon and zeolite post-treatment. 为无毒废水的生产水处理战略制定基准：将热蒸馏与颗粒活性炭和沸石后处理相结合。

Journal of hazardous materials Pub Date : 2024-10-05 Epub Date: 2024-08-17 DOI: 10.1016/j.jhazmat.2024.135549

Yeinner Tarazona, Haoyu B Wang, Mike Hightower, Pei Xu, Yanyan Zhang

{"title":"Benchmarking produced water treatment strategies for non-toxic effluents: Integrating thermal distillation with granular activated carbon and zeolite post-treatment.","authors":"Yeinner Tarazona, Haoyu B Wang, Mike Hightower, Pei Xu, Yanyan Zhang","doi":"10.1016/j.jhazmat.2024.135549","DOIUrl":"10.1016/j.jhazmat.2024.135549","url":null,"abstract":"The management of produced water (PW) generated during oil and gas operations requires effective treatment and comprehensive chemical and toxicological assessment to reduce the environmental risks associated with reuse or discharge. This study evaluated a treatment train that included a low-temperature thermal distillation pilot system followed by granular activated carbon (GAC) and zeolite post-treatment for processing hypersaline Permian Basin PW. Our study provides a unique and comprehensive assessment of the treatment efficiency considering a targeted chemical scheme together with whole effluent toxicity (WET) tests across four trophic levels regarding aquatic critical receptors of concern (ROC): Raphidocelis subcapitata, Vibrio fischeri, Ceriodaphnia dubia, and Danio rerio. The distillate from the thermal distillation process met various numeric discharge standards for salinity and major ions. However, it did not meet toxicity requirements established by the United States National Pollutant Discharge Elimination System program. Subsequent post-treatment using GAC and zeolite reduced the concentration of potential stressors, including volatile organics, NH3, Cd, Cr, Zn, and Mn in the final effluent to below detection limits. This resulted in a consistent toxicity reduction across all WET tests, with no observable adverse effects for R. subcapitata, C. dubia, and D. rerio (no observed effect concentration >100%), and V. fischeri effects reduced to 19%. This study realizes the feasibility of treating PW to non-toxic levels and meeting reuse and discharge requirements. It underscores the importance of implementing integrated treatment trains to remove the contaminants of concern and provides a systematic decision framework to predict and monitor environmental risks associated with PW reuse.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"478 ","pages":"135549"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142038056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cd exposure confers β-cypermethrin tolerance in Lymantria dispar by activating the ROS/CnCC signaling pathway-mediated P450 detoxification. 通过激活 ROS/CnCC 信号通路介导的 P450 解毒作用，镉暴露可赋予 Lymantria dispar 对β-氯氰菊酯的耐受性。

Journal of hazardous materials Pub Date : 2024-10-05 Epub Date: 2024-08-16 DOI: 10.1016/j.jhazmat.2024.135566

Mingtao Tan, Hong Jiang, Rusong Chai, Miao Fan, Zengting Niu, Guotong Sun, Shanchun Yan, Dun Jiang

{"title":"Cd exposure confers β-cypermethrin tolerance in Lymantria dispar by activating the ROS/CnCC signaling pathway-mediated P450 detoxification.","authors":"Mingtao Tan, Hong Jiang, Rusong Chai, Miao Fan, Zengting Niu, Guotong Sun, Shanchun Yan, Dun Jiang","doi":"10.1016/j.jhazmat.2024.135566","DOIUrl":"10.1016/j.jhazmat.2024.135566","url":null,"abstract":"Heavy metal pollutants are important abiotic environmental factors affecting pest habitats. In this study, Cd pre-exposure significantly increased the tolerance of Lymantria dispar larvae to β-cypermethrin, but did not significantly alter their tolerance to λ-cyhalothrin and bifenthrin. The activation of P450 by Cd exposure is the key mechanism that induces insecticide cross-tolerance in L. dispar larvae. Both before and after β-cypermethrin treatment, Cd exposure significantly increased the expression of CYP6AB224 and CYP6AB226 in L. dispar larvae. Silencing CYP6AB224 and CYP6AB226 reduced the tolerance of Cd-treated L. dispar larvae to β-cypermethrin. Transgenic CYP6AB224 and CYP6AB226 genes significantly increased the tolerance of Drosophila and Sf9 cells to β-cypermethrin, and the recombinant proteins of both genes could significantly metabolise β-cypermethrin. Cd exposure significantly increased the expression of CnCC and Maf. CnCC was found to be a key transcription factor regulating CYP6AB224- and CYP6AB226-activated insecticide cross-tolerance in Cd-treated larvae. Decreasing reactive oxygen species (ROS) levels in the Cd-treated larvae or increasing ROS levels in the untreated larvae reduced or enhanced the expression of CnCC, CYP6AB224 and CYP6AB226 and β-cypermethrin tolerance in L. dispar larvae, respectively. Collectively, Cd exposure confers β-cypermethrin tolerance in L. dispar larvae through the ROS/CnCC signalling pathway-mediated P450 detoxification.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"478 ","pages":"135566"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142038059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0