Journal of gastrointestinal and liver diseases : JGLD最新文献

{"title":"A rare case of small intestine ulcers, bleeding, obstruction, and perforation caused by amyloidosis.","authors":"Yanhong Gao, Ran Wang, Jie Mao, Cheng Zhang, Xingshun Qi","doi":"10.15403/jgld-5970","DOIUrl":"https://doi.org/10.15403/jgld-5970","url":null,"abstract":"","PeriodicalId":94081,"journal":{"name":"Journal of gastrointestinal and liver diseases : JGLD","volume":"34 2","pages":"263-264"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lichenoid Esophagitis: A Clinicopathological Comparison with Lymphocytic and Eosinophilic Esophagitis.","authors":"Salima Haque, S Maral K Mohammadi, Anuradha Singhal, Amnon Sonnenberg, Robert Maximilian Genta, Massimo Rugge","doi":"10.15403/jgld-6048","DOIUrl":"https://doi.org/10.15403/jgld-6048","url":null,"abstract":"<p><strong>Background and aims: </strong>Lichenoid esophagitis (LichE) is rarely encountered by gastrointestinal endoscopists. Using a large nationwide database of clinicopathological records, the demographic and clinical characteristics of patients with LichE were compared to patients with lymphocytic esophagitis (LyE) and eosinophilic esophagitis (EoE).</p><p><strong>Methods: </strong>In a case-control study, cases with a diagnosis of LichE, LyE, or EoE were compared to a control population of all patients without these 3 conditions. In addition to histopathology, patients' demographics, clinical presentation, and gastrointestinal comorbidities were considered. Statistical significance was assessed using odds ratios (OR) and 95% confidence intervals (95%CI).</p><p><strong>Results: </strong>Among 967,773 unique patients with esophageal biopsies, LichE was found in 511 (0.05%), LyE in 1,786 (0.18%), EoE in 56,474 (5.84%), and none of these 3 diagnoses in a control population of 909,002 patients. LichE patients were significantly older, and EoE patients were significantly younger than the control population (p<0.0001). LichE and LyE significantly prevailed in females (OR=1.69; 95%CI: 1.40-2.04 and 1.34; 1.22-1.47, respectively). EoE was significantly less common in females (OR=0.49; 95%CI: 0.48-0.49). All 3 types of esophagitis were significantly less common among Hispanics, with their respective ORs of 0.70 (95%CI: 0.50-0.98), 0.83 (95%CI: 0.70-0.98), and 0.55 (95%CI: 0.53-0.57). EoE was also less common in persons of East and South Asian ancestry, with respective ORs of 0.52 (95%CI: 0.47-0.56) and 0.66 (95%CI: 0.56-0.76).</p><p><strong>Conclusions: </strong>Increasing clinical awareness of LichE may enhance its clinico-pathological recognition, clarify its natural history, and ultimately lead to more effective clinical management.</p>","PeriodicalId":94081,"journal":{"name":"Journal of gastrointestinal and liver diseases : JGLD","volume":"34 2","pages":"157-162"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Yield of Prioritization of Gastrointestinal Endoscopy Activities According to the European Society of Gastrointestinal Endoscopy Recommendations.","authors":"Rachel Gingold-Belfer, Alon Ikan Amam, Igor Bouguslavskly, Yelena Chechulin, Doron Boltin, Zohar Levi, Maya Aharoni Golan","doi":"10.15403/jgld-5949","DOIUrl":"https://doi.org/10.15403/jgld-5949","url":null,"abstract":"<p><strong>Background and aims: </strong>Endoscopic procedures prioritization is an important tool for defining healthcare resources distribution in a daily practice and more important in times of limited resources such as the COVID 19 pandemic. We assessed the completion rate of endoscopic procedures that were canceled by the patients themself, based on the prioritization strategy recommended by the European Society of Gastrointestinal Endoscopy (ESGE) and examine what were the outcomes of the procedures' cancellation according to the endoscopic different indications.</p><p><strong>Methods: </strong>Retrospective analysis of all the self-cancelled procedures during March 2020 at our tertiary endoscopic referral center. The completion rate was estimated until July 2021. The procedure's primary indications were classified according to the ESGE position statement (\"always perform/high priority\" vs. \"low-priority/postpone always\"); Endoscopic findings were classified as \"significant\", defined as advanced neoplasia/ a clinically significant intervention, or \"other\".</p><p><strong>Results: </strong>We included 194 patients (mean age 60.4±15.3 years old; 44.8% females, 90.7% colonoscopies, 20.1% classified as \"always perform/ high priority\"). The completion rate in the \"perform always/high priority\" groups versus the \"low-priority/postpone always\" groups was 51.3% versus 70.3%, (p=0.024). In contrast, the rate of significant endoscopic findings in the \"perform always/high priority\" groups versus the \"low-priority/postpone always\" groups was 40.0% versus 7.3%, (p<0.001).</p><p><strong>Conclusions: </strong>Patients who are prioritized according to the ESGE classification have a higher rate of significant findings but a lower likelihood of completing the procedure. This highlights the need for improving implementation of prioritization strategy based on the ESGE classification.</p>","PeriodicalId":94081,"journal":{"name":"Journal of gastrointestinal and liver diseases : JGLD","volume":"34 2","pages":"227-231"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Comparison of Initial vs. Subsequent Simultaneous Side-by-Side Stenting with Uncovered Metal Stents during Endoscopic Retrograde Cholangiopancreatography for Unresectable Malignant Hilar Biliary Obstructions.","authors":"Koji Takahashi, Hiroshi Ohyama, Motoyasu Kan, Mayu Ouchi, Hiroki Nagashima, Kohichiroh Okitsu, Izumi Ohno, Naoya Kato","doi":"10.15403/jgld-5933","DOIUrl":"https://doi.org/10.15403/jgld-5933","url":null,"abstract":"<p><strong>Background and aims: </strong>This study aimed to evaluate the efficacy and safety of transpapillary simultaneous side-by-side (SBS) stenting using uncovered self-expandable metal stents (UCSEMSs) at the initial endoscopic retrograde cholangiopancreatography (ERCP) for unresectable malignant hilar biliary obstruction (UMHBO).</p><p><strong>Methods: </strong>A total of 67 patients with UMHBO who underwent simultaneous SBS stenting at our institution were retrospectively divided into two groups: the SBS stenting at the initial ERCP group (n=13) and the SBS stenting at the subsequent ERCP group (n=54). Clinical outcomes were compared between the groups.</p><p><strong>Results: </strong>There were no significant differences between the SBS stenting at the initial ERCP group and the SBS stenting at the subsequent ERCP group in procedural time (median: 50 vs. 40 minutes, p=0.31), functional success rate (69.2% vs. 83.3%, p=0.25), adverse event rate (30.8% vs. 14.8%, p=0.18), recurrent biliary obstruction (RBO) rate (23.1% vs. 38.9%, p=0.29), technical success rate of re-intervention (100% vs. 90.5%, p=0.58), cumulative time to RBO (not reached vs. 252 days, p=0.80), or median overall survival (73 vs. 212 days, p=0.12).</p><p><strong>Conclusions: </strong>Simultaneous SBS stenting using UCSEMSs at the initial ERCP is a safe and effective strategy for managing UMHBO, with outcomes comparable to those of SBS stenting performed at the subsequent ERCP.</p>","PeriodicalId":94081,"journal":{"name":"Journal of gastrointestinal and liver diseases : JGLD","volume":"34 2","pages":"214-219"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Cause of Acute Gastrointestinal Haemorrhage: Bleeding Gastric Diverticulum.","authors":"Matthew Peverelle, Benhur Reynauld","doi":"10.15403/jgld-5847","DOIUrl":"https://doi.org/10.15403/jgld-5847","url":null,"abstract":"","PeriodicalId":94081,"journal":{"name":"Journal of gastrointestinal and liver diseases : JGLD","volume":"34 2","pages":"151"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fibrosis Regression of Advanced Chronic Liver Disease Outlined by a Novel Histological Classification.","authors":"Muriel Ducousso, Matteo Montani, Jaime Bosch, Annalisa Berzigotti, Yuly Paulin Mendoza","doi":"10.15403/jgld-6018","DOIUrl":"https://doi.org/10.15403/jgld-6018","url":null,"abstract":"<p><p>In the past, advanced chronic liver disease was considered irreversible, but with better understanding and improved treatments, it is now recognized that fibrosis is a dynamic process that can regress even when it has reached the stage of cirrhosis. We present the case of a 60-year-old male patient with advanced chronic liver disease due to chronic hepatitis B, whose follow-up liver biopsy revealed significant fibrosis regression after successful antiviral therapy. We confirmed the predominantly regressive pattern using the P-I-R classification, a new histological classification that defines the tissue features as predominantly \"Progressive, Intermediate or Regressive\" by comparing stroma to parenchymal ratios. Furthermore, we also point out the prognostic value of P-I-R classification, as the patient has remained free of decompensation over time. In this clinical case, we highlight important aspects of the pathophysiology and histopathology of cirrhosis regression, emphasizing its critical prognostic significance. Finally, familiarizing clinicians and pathologists with the application of the P-I-R classification may improve prognostication based on histology in patients with advanced liver disease.</p>","PeriodicalId":94081,"journal":{"name":"Journal of gastrointestinal and liver diseases : JGLD","volume":"34 2","pages":"256-259"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Plastic Stent for the Treatment of Incomplete Clearance of Common Bile Duct Stone: A Systematic Review and Meta-analysis.","authors":"Marco Valvano, Antonio Vinci, Filippo Antonini, Amedeo Montale, Annalisa Capannolo, Stefano Fabiani, Gianpiero Stefanelli, Marco Magistroni, Marta Mosca, Susanna Faenza, Fabio Ingravalle, Mariachiara Campanale, Maurici Massimo, Giovanni Latella","doi":"10.15403/jgld-5964","DOIUrl":"10.15403/jgld-5964","url":null,"abstract":"<p><strong>Background and aims: </strong>Common bile duct stones (CBDs) can typically be treated by endoscopic retrograde cholangiopancreatography (ERCP) in 85-90% of cases. However, in the remaining 10-15% of patients, bile duct stones cannot be extracted. In such cases, the placement of a temporary biliary plastic stent is recommended.</p><p><strong>Methods: </strong>We conducted a systematic review and meta-analysis (PROSPERO registration number: CRD42023459712; October 2023). An electronic search was carried out using the following databases: PubMed/MEDLINE, Scopus, and CENTRAL (last search: October 20, 2023). All published studies (both randomized clinical trials and non-randomized interventional studies) involving patients who had undergone ERCP for CBDs with incomplete biliary clearance were included. The risk of bias was assessed using the RoB 2.0 and ROBINS-I tools. The confidence in network meta-analysis tool was employed to estimate each study's contribution matrix within the network estimate.</p><p><strong>Results: </strong>Twenty papers (comprising 902 patients) were selected for qualitative and quantitative synthesis and were included in the standard meta-analysis, while only five studies (254 patients) were used for the network meta-analysis. The pooled success rate of stenting intervention in difficult choledocholithiasis was 79% (95% CI:71-87%). In the network meta-analysis model, ursodeoxycholic acid and single or double stenting resulted in a higher probability of being the most effective treatments.</p><p><strong>Conclusions: </strong>In cases of incomplete CBD clearance, the insertion of a temporary plastic stent achieves complete clearance in 79% of patients. Although not significantly superior in indirect comparison with stent alone, the adjunctive treatment with ursodeoxycholic acid appears to be the most likely to succeed.</p>","PeriodicalId":94081,"journal":{"name":"Journal of gastrointestinal and liver diseases : JGLD","volume":"34 2","pages":"232-240"},"PeriodicalIF":2.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left Sided Diaphragmatic Eventration: A Rare Cause of Recurrent Vomiting.","authors":"Sanjeev Sachdeva, Ravi Teja Reddy, Kartik Mehta, Aarushi Ahuja","doi":"10.15403/jgld-5976","DOIUrl":"https://doi.org/10.15403/jgld-5976","url":null,"abstract":"","PeriodicalId":94081,"journal":{"name":"Journal of gastrointestinal and liver diseases : JGLD","volume":"34 2","pages":"153"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fecal Microbiome Transplantation for Recurrent CDI: Treatment Efficacy and Safety with Oral Capsules.","authors":"Tadas Urbonas, Dalius Petrauskas, Vytautas Kiudelis, Laimas Jonaitis, Jurgita Skieceviciene, Rolandas Gedgaudas, Edita Kiudeliene, Irena Valantiene, Romanas Zykus, Greta Varkalaite, Ruta Inciuraite, Elzbieta Trapenske, Ugne Kulokiene, Paulius Jonaitis, Rima Ramonaite, Justina Velickiene, Aida Zvirbliene, Egidijus Morkunas, Irma Kuliaviene, Jolanta Sumskiene, Kestutis Adamonis, Andrius Macas, Kristina Kupcinskiene, Laura Lukosiene, Dainius Janciauskas, Lina Poskiene, Astra Vitkauskiene, Gianluca Ianiro, Antonio Gasbarrini, Gediminas Kiudelis, Juozas Kupcinskas","doi":"10.15403/jgld-5990","DOIUrl":"https://doi.org/10.15403/jgld-5990","url":null,"abstract":"<p><strong>Background and aims: </strong>Fecal microbiota transplantation is an effective treatment method for recurrent Clostridioides difficile infection. Widely used enteric tube and colonoscopy methods demonstrate excellent efficacy and safety results. Recent data suggest that new fecal microbiota transplantation methods using oral capsules may provide a less invasive approach. In this study, we aimed to compare primary fecal microbiota transplantation efficacy as well as short- and long-term safety of two different administration routes: oral capsules and enteric tube.</p><p><strong>Methods: </strong>This retrospective study included 60 consecutive patients who underwent fecal microbiota transplantation for recurrent Clostridioides difficile infection. Thirty participants received 50 oral capsules containing frozen material for a single day and 30 patients received fecal microbiota transplantation via nasoenteric tube. All patients received standard treatment with oral vancomycin 500 mg q.i.d. for at least five days before the procedure. After intervention, patients were followed up for at least six months. Data on Clostridioides difficile infection recurrences and health status were collected and analyzed.</p><p><strong>Results: </strong>The oral capsules group consisted of 30 patients. Among them, 22 (73.3%) participants experienced resolution of symptoms after a single fecal microbiota transplantation, while eight (26.7%) patients developed recurrent diarrhea within eight weeks. The other 30 patients received treatment via nasoenteric tube. Among them, 24 (80%) patients were cured after a single fecal microbiota transplantation, while six (20%) experienced recurrent disease within eight weeks. The primary efficacy did not show significant differences between the two groups (p=0.85). Throughout the follow-up period, no serious adverse events or fecal microbiota transplantation related deaths were reported in both groups.</p><p><strong>Conclusions: </strong>Fecal microbiota transplantation with frozen oral capsules is a safe, less invasive method with comparable efficacy to nasoenteric administration route.</p>","PeriodicalId":94081,"journal":{"name":"Journal of gastrointestinal and liver diseases : JGLD","volume":"34 2","pages":"199-204"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metastatic Malignant Melanoma: A Case Possibly Originating from the Duodenum.","authors":"Omer Kucukdemirci, Asli Akcay, Yakup Baris Sancar, Hasan Eruzun, Ufuk Avcioglu","doi":"10.15403/jgld-5927","DOIUrl":"https://doi.org/10.15403/jgld-5927","url":null,"abstract":"","PeriodicalId":94081,"journal":{"name":"Journal of gastrointestinal and liver diseases : JGLD","volume":"34 2","pages":"154"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}