Journal of forensic sciences最新文献_第7页

Chemical profiling of developmental stages in three major flies via direct infusion mass spectrometry: Improving estimates of minimum postmortem intervals in forensic entomology. 通过直接输注质谱分析三种主要蝇类发育阶段的化学特征：改进法医昆虫学中最小死后间隔的估计。

Journal of forensic sciences Pub Date : 2025-07-06 DOI: 10.1111/1556-4029.70126

Davi Rodrigues da Silva, Alicia Camacho Dos Santos, Iasmim Lopes de Lima, Felipe Raposo Passos de Mansoldo, Adriano Reis José da Silva, Caroline Pais de Carvalho, Gustavo Santana da Cunha, Mariana Magalhães Borges, Alane Beatriz Vermelho, Jez Willian Batista Braga, Marcos Nogueira Eberlin

{"title":"Chemical profiling of developmental stages in three major flies via direct infusion mass spectrometry: Improving estimates of minimum postmortem intervals in forensic entomology.","authors":"Davi Rodrigues da Silva, Alicia Camacho Dos Santos, Iasmim Lopes de Lima, Felipe Raposo Passos de Mansoldo, Adriano Reis José da Silva, Caroline Pais de Carvalho, Gustavo Santana da Cunha, Mariana Magalhães Borges, Alane Beatriz Vermelho, Jez Willian Batista Braga, Marcos Nogueira Eberlin","doi":"10.1111/1556-4029.70126","DOIUrl":"https://doi.org/10.1111/1556-4029.70126","url":null,"abstract":"Forensic entomology has become an essential tool for estimating the minimum postmortem interval (mPMI), especially in scenarios where traditional methods are limited. This study aimed to characterize and differentiate the chemical profiles of three major forensically relevant fly species-Chrysomya albiceps, Cochliomyia macellaria, and Lucilia cuprina-across their developmental stages. Changes in chemical profiles during larval, pupal, and pharate adult stages were monitored via ethanol-based solvent extraction followed by direct infusion mass spectrometry (DIMS). Distinct chemical fingerprints were observed for each stage, with specific variations in ion compositions reflecting the dynamic nature of insect development. Chemometric analysis using PLS-DA models clearly distinguished the species and their developmental stages, especially during the larval phase, which is critical for mPMI estimation. These findings demonstrate that metabolomic profiling combined with chemometric tools offers, in forensic investigations, a precise and robust approach to estimate mPMI and to identify fly species in their larval stages.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychotherapeutic treatment outcome of a female filicide patient. 一名女性杀子病人的心理治疗结果。

Journal of forensic sciences Pub Date : 2025-07-03 DOI: 10.1111/1556-4029.70125

Simone Giacco, Elisa Cristofaletti, Giuseppe Lucchini, Alessia Cicolini

{"title":"Psychotherapeutic treatment outcome of a female filicide patient.","authors":"Simone Giacco, Elisa Cristofaletti, Giuseppe Lucchini, Alessia Cicolini","doi":"10.1111/1556-4029.70125","DOIUrl":"https://doi.org/10.1111/1556-4029.70125","url":null,"abstract":"A case of double filicide of both her children admitted to a forensic psychiatric facility is described. According to the CARE guidelines (for CAse REports), a full description of the patient, clinical and diagnostic scenarios, the crime, psychotherapy treatment, and changes in psychopathological functioning and clinical outcome are outlined. The patient's psychopathological functioning and clinical outcome were assessed during treatment with the MMPI-2 test: 6 months after filicide (T0), after 2 years of psychotherapy treatment (T1), and prior to discharge/after 5 1/2 years of psychotherapy treatment (T2). The psychotherapeutic pathway was characterized by a supportive and expressive intervention, guiding the revision of the patient's own experiences and of those around her, the revisitation of thoughts from alternative points of view, increasing mentalization and integration capabilities of personality, and external aspects of reality. Over the course of detention, assessments of psychopathological functioning highlighted a decrease in impulsivity and perceived conflict with family members, a decreased tendency to externalize responsibilities, an adequate perception of reality, and dysthymia (rather than depression revealed at treatment initiation). The patient was discharged to a community psychiatric facility, and clinical outcomes were maintained at 12 months post-discharge. Psychotherapy, together with pharmacological treatment, encouraged and enabled the patient to develop insights into the link between her illness and filicide, reduce her externalization of personal behavioral responsibility, and improve her perception of interfamily relational conflict. The patient gradually acquired a greater acceptance of her grief.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining the effects of 3D printed projectiles on firearm identification. 研究3D打印弹丸对枪支识别的影响。

Journal of forensic sciences Pub Date : 2025-07-02 DOI: 10.1111/1556-4029.70122

Joseph R Vandenburgh

{"title":"Examining the effects of 3D printed projectiles on firearm identification.","authors":"Joseph R Vandenburgh","doi":"10.1111/1556-4029.70122","DOIUrl":"https://doi.org/10.1111/1556-4029.70122","url":null,"abstract":"In recent years, 3D printers have become more affordable for the average consumer to purchase, and new printers require less user input, making the process accessible to anyone who can download files online. Due to these factors, these printers are being used to manufacture firearms and firearm components privately. In 2023, New York began requiring background checks for anyone purchasing ammunition within the State, which may increase interest in manufacturing ammunition at home to bypass these background checks. This study addresses this potential problem by specifically examining 3D printed projectiles. It was found that 3D printed projectiles are suitable for use in a firearm and will acquire the class characteristics and individual characteristics of the rifling. These marks may enable the identification of a bullet to a specific firearm. However, the markings are hard to visualize due to the filament material, but can be enhanced by casting the projectile. The projectiles also exhibited reduced markings when compared with conventional bullets most likely due to the bearing surface of the projectile melting during the firing process. However, it was found that reducing the amount of propellant allowed more markings to be retained for comparison. Further testing revealed that the projectiles could perforate common obstacles, including drywall, plywood, and automotive glass, and penetrate a bulletproof vest. The projectiles also acquired markings from the printer's build plate, which can be used to connect the projectile back to the build plate. These findings reveal the similarities between 3D printed projectiles and conventional bullets.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seasonal decomposition and the effect of clothing in Cape Town, South Africa. 南非开普敦的季节分解和衣物的影响。

Journal of forensic sciences Pub Date : 2025-07-02 DOI: 10.1111/1556-4029.70128

Maximilian J Spies, Devin A Finaughty, Louise J Friedling, Victoria E Gibbon

{"title":"Seasonal decomposition and the effect of clothing in Cape Town, South Africa.","authors":"Maximilian J Spies, Devin A Finaughty, Louise J Friedling, Victoria E Gibbon","doi":"10.1111/1556-4029.70128","DOIUrl":"https://doi.org/10.1111/1556-4029.70128","url":null,"abstract":"Unidentified, unclaimed human remains are a substantial problem in many developing nations, including South Africa. Most forensic cases in Cape Town involve clothed individuals found in thicketed environments. To assist in local medico-legal death investigations, we gathered taphonomic data on six clothed and four unclothed 60 kg porcine bodies as proxies for human decay. This study took place in Delft, Cape Town, over two summers and two winters to assess the impact of seasonal variation, using weight loss, extent of bloat, and vertebrate scavenging as assessment markers. In Cape Town's temperate climate, decomposition in the hotter, drier summer season occurred more rapidly than in the significantly colder and rainier winters, regardless of the presence of clothing (summer vs. winter: 18 vs. 80 days to 68% mass loss, 4 vs. 24 days bloat duration). Double-layer cool-weather clothing caused a notable decrease in decomposition rate and altered scavenging behavior in winter (clothed vs. unclothed: 108 vs. 71 days to 68% mass loss, 364 vs. 622 scavenger visits). Single-layer warm-weather clothing had a comparatively negligible effect in summer (clothed vs. unclothed: 84 vs. 91 days to 68% mass loss, 318 vs. 294 scavenger visits). Although further validation is required, this study provides crucial information for forensic practitioners and researchers in the Cape. Death investigations that do not account for the influence of clothing and vertebrate scavenging on decomposition may be inaccurate, especially in environments where scavengers are known to be highly impactful agents of decay, such as the habitat currently under study.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lab-based evaluation of first- and second-generation gamma-hydroxybutyrate test strips and pads in beverages. 第一代和第二代饮料中γ -羟基丁酸试纸和衬垫的实验室评价。

Journal of forensic sciences Pub Date : 2025-07-02 DOI: 10.1111/1556-4029.70119

Alan H B Wu, Chui Mei Ong, Melissa Alamillo, Stephen Farias, Edie Feinstein, Patrick Chu

{"title":"Lab-based evaluation of first- and second-generation gamma-hydroxybutyrate test strips and pads in beverages.","authors":"Alan H B Wu, Chui Mei Ong, Melissa Alamillo, Stephen Farias, Edie Feinstein, Patrick Chu","doi":"10.1111/1556-4029.70119","DOIUrl":"https://doi.org/10.1111/1556-4029.70119","url":null,"abstract":"Gamma hydroxybutyrate (GHB) has been used as a drug to facilitate sexual assault. Commercial testing devices are available for bars and patrons to test drinks that may have been spiked with GHB. In this study, six first-generation GHB test devices were evaluated for the detection of GHB at 0.8, 1.6, 3.2, and 16 mg/mL in beverages containing rum, vodka, beer, sucrose, and red wine. These strips used bromocresol green, a dye-binding reagent. Two second-generation test devices that use gamma hydroxybutyric dehydrogenase, a reagent with high GHB specificity, were also evaluated. GHB at 0.10, 0.25, and 0.50 mg/mL was spiked into the above beverages plus orange juice, whiskey, and Diet Coke®. Prepared separately, water spiked with GHB was used as a positive control and unspiked beverages as negative controls. Two individuals conducted the preliminary tests on all devices and were unblinded to the drink composition. Four other individuals blinded to the final contents were asked to test a subset of these samples. There was complete concordance between the results of tests conducted by blinded individuals. Two first-generation products were insensitive to GHB at 16 mg/mL. The remaining first-generation tests produced positive results between 3.2 and 16 mg/mL. Colored beverages (whiskey, beer, and red wine) produced colors that interfered with reading some tests. Second-generation tests produced positive results at 0.5 mg/mL and were the most sensitive. In conclusion, the endpoints of these newer tests were superior to first-generation devices and sufficient to detect GHB at concentrations that could cause untoward effects.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The dermestid beetle (Dermestes maculatus) as a biotic taphonomic agent: Further recommendations for maintaining a dermestid beetle colony for processing remains. 作为生物灭虫剂的皮蝇甲虫：进一步建议维持皮蝇甲虫菌落以处理遗骸。

Journal of forensic sciences Pub Date : 2025-07-02 DOI: 10.1111/1556-4029.70118

Abraham B Packard, Gretchen R Dabbs

{"title":"The dermestid beetle (Dermestes maculatus) as a biotic taphonomic agent: Further recommendations for maintaining a dermestid beetle colony for processing remains.","authors":"Abraham B Packard, Gretchen R Dabbs","doi":"10.1111/1556-4029.70118","DOIUrl":"https://doi.org/10.1111/1556-4029.70118","url":null,"abstract":"The dermestid beetle (Dermestes maculatus) has become renowned in the laboratory as an aid to skeletonization of remains. However, little attention has been paid to the potential effects these insects can have on hard tissues and whether their traces may be mistaken for trauma or the effects of other taphonomic processes. Dermestids are known to bore pupal chambers in surrounding materials at the end of their larval stage. The potential effects of dermestid beetles were tested by a choice experiment based on ASTM D3345-17, examining the behavior of D. maculatus regarding expanded polystyrene, wood, and two types of bone. Specifically, this project tested (1) whether the beetles showed preference in the creation of pupation chambers for a particular material (of expanded polystyrene, wood, dry bone, or green bone), (2) whether material type had an impact on survivorship from the larval to adult stage, and (3) what traces, if any, dermestids leave on skeletal remains and the variation in form of those traces. Taphonomic impacts of D. maculatus larvae on two types of hard tissue were documented. Results suggest dermestid beetles preferentially bore pupal chambers in softer materials (expanded polystyrene > wood > dry bone > green bone), but preference is not absolute. Preference did not impact survivorship. Information on the \"typical\" form of dermestid trace on materials is presented, as an aid to identifying these features as resulting from taphonomic processes. Recommendations for colony setup to avoid trace formation are made.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characteristics and toxicology of adult deaths due to quetiapine toxicity in Australia, 2000-2024. 2000-2024年澳大利亚喹硫平毒性导致的成人死亡的特征和毒理学

Journal of forensic sciences Pub Date : 2025-06-30 DOI: 10.1111/1556-4029.70124

Shane Darke, Johan Duflou, Julia Lappin, Michael Farrell, Amy Peacock

{"title":"Characteristics and toxicology of adult deaths due to quetiapine toxicity in Australia, 2000-2024.","authors":"Shane Darke, Johan Duflou, Julia Lappin, Michael Farrell, Amy Peacock","doi":"10.1111/1556-4029.70124","DOIUrl":"https://doi.org/10.1111/1556-4029.70124","url":null,"abstract":"Quetiapine is an atypical antipsychotic that has been associated with both intentional and unintentional deaths. We aimed to determine, stratified by intentionality: (1) The characteristics and circumstances of adult deaths attributed solely to quetiapine toxicity in Australia, 2000-2024; (2) The blood toxicology of cases for quetiapine and other drugs; and (3) The major autopsy findings for cardiovascular, lung, kidney, and liver disease. All cases of death aged ≥15 years attributed solely to quetiapine toxicity in Australia, 2000-2024, were retrieved from the National Coronial Information System. We identified 136 adult cases attributed solely to quetiapine toxicity. In 64.7% (n = 88), the fatal poisoning was deemed intentional, unintentional in 19.9% (n = 27), and of undetermined intent in 15.4% (n = 21). The mean age was 42.4 years (range 15-69) and 58.1% (n = 79) were male. A history of mental health problems was documented in 92.6% (n = 126). The median quetiapine concentration was 12.0 mg/L (range 1.2-600.0), with that of intentional cases being twice that of unintentional cases (13.0 vs. 6.3 mg/L). Other psychotropic drugs not considered contributory to death were present in 73.0% (n = 92) of cases, most commonly hypnosedatives (34.1%, n = 43) and antidepressants (33.3%, n = 42). Hearts were examined in 87 cases, of which 31.0% (n = 27) were diagnosed with cardiovascular disease. Given these findings, screening patients prescribed quetiapine for suicide histories and ideation is prudent, as is monitoring cardiovascular disease. For forensic pathologists, the extent and nature of cardiovascular disease appear important for the formulation of death, and suicide should be borne in mind.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From theory to practice: Protocol adaptations for swift victim identification in the forensic response to the October 7, 2023, Hamas massacre. 从理论到实践：2023年10月7日哈马斯大屠杀的法医反应中快速识别受害者的协议调整。

Journal of forensic sciences Pub Date : 2025-06-30 DOI: 10.1111/1556-4029.70127

Esi Sharon, Tzipi Kahana, Sarena Wiesner, Yael Herman, Naftaly Einot, Uri Argaman

{"title":"From theory to practice: Protocol adaptations for swift victim identification in the forensic response to the October 7, 2023, Hamas massacre.","authors":"Esi Sharon, Tzipi Kahana, Sarena Wiesner, Yael Herman, Naftaly Einot, Uri Argaman","doi":"10.1111/1556-4029.70127","DOIUrl":"https://doi.org/10.1111/1556-4029.70127","url":null,"abstract":"The October 7, 2023, massacre in Israel posed unprecedented challenges for disaster victim identification (DVI), requiring adaptations to international forensic protocols to address extreme conditions, including active conflict, fragmented remains, and cultural and religious constraints. The urgency of establishing a list of missing persons and establishing whether individuals were deceased or taken hostage, and in turn distinguishing victims from perpetrators, complicated the process. This study examines the modifications and innovations implemented throughout the DVI operation, integrating international best practices with locally adapted strategies. Key adaptations included enhanced interagency coordination and novel forensic identification techniques. Despite the unprecedented scale and complexity of this DVI incident for Israel, 96% of the 1200 victims were identified within 3 weeks. The operation underscored the critical importance of adaptability, real-time collaboration, and technological innovation in mass fatality response.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Digital otoscopic examination of tympanic membranes in confirmed suicidal hanging deaths: Preliminary autopsy study. 数字耳镜检查鼓膜确认自杀上吊死亡：初步尸检研究。

Journal of forensic sciences Pub Date : 2025-06-27 DOI: 10.1111/1556-4029.70120

Anupriya S Nair, Vikas Meshram, Raghvendra Singh Shekhawat, Kapil Soni, Sudeep Khera, Tanuj Kanchan

{"title":"Digital otoscopic examination of tympanic membranes in confirmed suicidal hanging deaths: Preliminary autopsy study.","authors":"Anupriya S Nair, Vikas Meshram, Raghvendra Singh Shekhawat, Kapil Soni, Sudeep Khera, Tanuj Kanchan","doi":"10.1111/1556-4029.70120","DOIUrl":"https://doi.org/10.1111/1556-4029.70120","url":null,"abstract":"A crucial factor in cases of apparent hanging deaths is establishing whether an antemortem hanging or postmortem suspension has occurred. Hanging diagnosis relies upon the history, scene investigation, and gross examination of the body including the ligature furrow and possible resultant injuries including hemorrhages, fractures, and petechiae. However, pathognomonic changes are lacking. Examination of the tympanic membrane may provide additional information to assist in distinguishing antemortem hanging from postmortem suspension. The changes in the tympanic membrane in cases of hanging deaths have not been extensively studied, with only a few case reports available on the subject. The common findings seen on otoscopy in hanging deaths are hemotympanum, petechial hemorrhages, and otorrhagia. In our study, we included 30 cases of confirmed suicidal hanging deaths and 15 non hanging cases as control. Among 30 cases of confirmed suicidal hanging deaths, bilateral hemotympanum was observed in 29 cases. Among these 29 cases of bilateral hemotympanum, one case showed bilateral otorrhagia along with bilateral hemotympanum, while another case showed unilateral right-sided otorrhagia with bilateral hemotympanum. None of the cases showed presence of petechial hemorrhage exclusively. These changes were independent of age, sex, type of hanging, type of ligature material, and position of the knot. None of the controls showed evidence of petechial hemorrhages, hemotympanum, or otorrhagia. Otoscopy can be employed as a simple, non-invasive method to study the changes in the tympanic membrane and may be an adjunct to determining vitality in hanging deaths.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Micro-CT for the differentiation between live birth and stillbirth: A pilot study. 显微ct鉴别活产和死产：一项初步研究。

Journal of forensic sciences Pub Date : 2025-06-26 DOI: 10.1111/1556-4029.70113

Giovanni Botta, Tullio Genova, Alessandro Bonsignore, Francesca Buffelli, Davide Mussano, Francesco Lupariello

{"title":"Micro-CT for the differentiation between live birth and stillbirth: A pilot study.","authors":"Giovanni Botta, Tullio Genova, Alessandro Bonsignore, Francesca Buffelli, Davide Mussano, Francesco Lupariello","doi":"10.1111/1556-4029.70113","DOIUrl":"https://doi.org/10.1111/1556-4029.70113","url":null,"abstract":"The distinction between live births and stillbirths is crucial for determining the appropriate legal consequences. Historically, researchers have operated under the principle that an infant's lungs will be filled with air upon death, whereas a fetus's lungs will not. The flotation test for the lungs is the primary method still used in many jurisdictions. However, there are concerns regarding its reliability. For this reason, we conducted a pilot study to evaluate the feasibility of postmortem micro-computed tomography (micro-CT) for differentiating between formalin-fixed aerated and nonaerated lungs. Lung samples from aerated (Group 1) and nonaerated (Group 2) subjects were scanned using micro-CT. We calculated the gas volume percentage (GV%) in each sample. Group 1 (aerated lungs) showed a mean GV% of 9.52 ± 6.77, while Group 2 (nonaerated lungs) showed a mean GV% of 0.58 ± 0.66. These findings suggest that micro-CT can qualitatively and quantitatively detect pulmonary aeration and may serve as a valuable tool in forensic investigations involving suspected neonaticide, feticide, and intrauterine fetal demise.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144510070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0