Journal of forensic sciences最新文献_第7页

Venous aneurysm leading to fatal pulmonary thromboembolism with a history of a remote stab wound of the extremity. 静脉动脉瘤导致致命的肺血栓栓塞与历史远端刺伤的四肢。

Journal of forensic sciences Pub Date : 2024-12-06 DOI: 10.1111/1556-4029.15687

Emily Helmrich, Erin Risotto-Urbanowicz, Pierce Massie, Ross Clark

{"title":"Venous aneurysm leading to fatal pulmonary thromboembolism with a history of a remote stab wound of the extremity.","authors":"Emily Helmrich, Erin Risotto-Urbanowicz, Pierce Massie, Ross Clark","doi":"10.1111/1556-4029.15687","DOIUrl":"https://doi.org/10.1111/1556-4029.15687","url":null,"abstract":"Venous aneurysms are rare, and their incidence is unknown. External iliac vein aneurysms are even more rare with only 50 case reports published from 1950 to 2018. We present a case of an individual who died suddenly from a pulmonary thromboembolic event due to an external iliac vein aneurysm formed by a remote penetrating injury. A 32-year-old male was in Immigration and Customs Enforcement (ICE) custody when he died suddenly. It was discovered during his autopsy that he had an occlusive pulmonary thromboembolism (PE) within the left main pulmonary artery and distal branches of the right pulmonary artery. On additional investigation and postmortem computed tomography, a large saccular aneurysm arising from the external iliac vein was discovered. This aneurysm contained clotted blood, and was determined to be the cause of his PE and subsequent death. Although rarely a source for a fatal PE, venous aneurysms should be considered as a possible source for thromboembolism; their presence may alter the manner of death, given their underlying etiology. This is especially true for young adults with a remote history of trauma near a major venous tributary, as traumatic arteriovenous fistula is a common cause of secondary venous aneurysm. For this case, the manner of death was classified as homicide.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142788161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Generative-adversarial network for falsification of handwritten signatures. 生成对抗网络伪造手写签名。

Journal of forensic sciences Pub Date : 2024-12-04 DOI: 10.1111/1556-4029.15680

Maciej Marcinowski-Prażmowski

引用次数: 0

Report of forensically relevant insects collected from pig and rabbit remains during two forensic entomology workshops in Eastern Massachusetts. 在马萨诸塞州东部两次法医昆虫学研讨会期间从猪和兔子遗骸中采集的法医相关昆虫报告。

Journal of forensic sciences Pub Date : 2024-12-04 DOI: 10.1111/1556-4029.15681

Samantha J Sawyer

{"title":"Report of forensically relevant insects collected from pig and rabbit remains during two forensic entomology workshops in Eastern Massachusetts.","authors":"Samantha J Sawyer","doi":"10.1111/1556-4029.15681","DOIUrl":"https://doi.org/10.1111/1556-4029.15681","url":null,"abstract":"Forensic entomology relies on known geographic ranges and seasonal presence of forensically relevant insects. In the Northeastern United States, there is no information on species in the region in early spring. Two forensic entomology workshops took place in April of 2023 and 2024 in Milton, Massachusetts. During this workshop, practitioners were trained in the appropriate collection and storage techniques prior to a practical experience including the collection of insects from pig and rabbit remains. All insects collected were identified down to family or species level. Across both years, Phormia regina (Meigen) (Diptera: Calliphoridae) was the fly consistently colonizing remains and was the oldest immature larvae in all instances. Calliphora vicina (Robineau-Desvoidy) (Diptera: Calliphoridae), Protophormia terraenovae (Robineau-Desvoidy) (Diptera: Calliphoridae), and Muscina stabulans (Fallén) (Diptera: Muscidae) were additional flies co-colonizing remains with P. regina. Other species were found as adults surrounding the remains that included other necrophagous fly species, beetles, and ants. Variation in insects collected between years likely due to high temperature variation. This documentation of species provides context to forensically related flies expected in Eastern Massachusetts and provides research directives in the region.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative transcriptomic analysis provides novel insights into mescaline biosynthesis by Lophophora williamsii. 比较转录组学分析为了解威廉希尔手机版的麦司卡林生物合成提供了新的视角。

Journal of forensic sciences Pub Date : 2024-11-26 DOI: 10.1111/1556-4029.15679

Eun-Mi Hwang, Kyu-Sik Jeong, Seong Yeon Yoo, Jihyun Kim, Sanggil Choe, Joo-Young Kim

{"title":"Comparative transcriptomic analysis provides novel insights into mescaline biosynthesis by Lophophora williamsii.","authors":"Eun-Mi Hwang, Kyu-Sik Jeong, Seong Yeon Yoo, Jihyun Kim, Sanggil Choe, Joo-Young Kim","doi":"10.1111/1556-4029.15679","DOIUrl":"https://doi.org/10.1111/1556-4029.15679","url":null,"abstract":"Lophophora williamsii, known for mescaline synthesis, has raised legal and ethical considerations. However, L. williamsii specimens that do not contain mescaline have been recently identified, necessitating the development of techniques to differentiate between mescaline-positive and mescaline-negative groups. Genetic markers have been explored to differentiate these specimens, complementing gas chromatography/mass spectrometry analysis. Here, we used a single-molecule real-time polymerase chain reaction to generate a full-length L. williamsii transcriptome and elucidate the mechanisms underlying mescaline biosynthesis. In total, 2,839,819 base pairs of highly accurate long reads were obtained using PacBio Iso-Seq and 70,945 unigenes were obtained through transcriptome sequencing. Known genes involved in the mescaline biosynthetic pathway were confirmed in the L. williamsii transcriptome, including 6 genes encoding tyrosine decarboxylases, 1 encoding tyrosine/DOPA decarboxylase, 215 encoding O-methyltransferases, and 129 encoding hydroxylases. Gene Ontology analysis revealed 2903 biological processes, 695 cellular components, and 1766 molecular functions. The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis revealed two biosynthetic pathways, namely, phenylpropanoid and isoquinoline biosynthesis, associated with mescaline biosynthesis. To investigate genetic differences based on the presence of mescaline, Illumina Nova sequencing was conducted. The expression levels of genes involved in mescaline biosynthesis were compared to establish a candidate gene pool based on the presence of mescaline. Subsequently, functional annotation was performed on the identified candidate genes using a genetic database derived from PacBio sequencing. These findings underscore the need for a re-evaluation of forensic methods and legal regulations concerning newly identified L. williamsii specimens.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142735445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serial killer and necrophilia: Report of twenty-five years of treatment and management in a rare case. 连环杀手与恋尸癖：一个罕见病例二十五年的治疗和管理报告。

Journal of forensic sciences Pub Date : 2024-11-21 DOI: 10.1111/1556-4029.15675

Ilaria Rossetto, Filippo Franconi, Fulvio Carabellese, Gianfranco Rivellini, Lia Parente, Felice Carabellese

{"title":"Serial killer and necrophilia: Report of twenty-five years of treatment and management in a rare case.","authors":"Ilaria Rossetto, Filippo Franconi, Fulvio Carabellese, Gianfranco Rivellini, Lia Parente, Felice Carabellese","doi":"10.1111/1556-4029.15675","DOIUrl":"https://doi.org/10.1111/1556-4029.15675","url":null,"abstract":"The authors report a case of a sexual serial killer responsible for four homicides (one homosexual and three prostitutes) over a 12-year period. The perpetrator was diagnosed with a severe personality disorder and necrophilia at the time of the crimes and was declared partially mentally impaired and dangerous to societal security by the Court of Jurisdiction for these crimes. The offender served 22 years in prison, including half of the detention in an OPG (High Security Forensic Psychiatry Hospital) receiving psychiatric treatment. This was followed by 3 years of internment in the REMS (Residences for the Execution of Security Measures): these facilities are regional mental health community facilities, each accommodating 20 patients, established throughout Italian administrative division. Such facilities are designed for the accommodation and treatment of offenders who are either deemed not guilty by reason of insanity (NGRI) or declared totally mentally impaired (Articles 88, Italian Penal Code) or assessed as partially mentally impaired (Article 89 Italian Penal Code), typically following reduced imprisonment terms. The case documents the history of schizophrenic disorder, the development of serial killers' behavior during incarceration, and the comprehensive process of treatment and management that encompasses 25 years. Cases documenting the evolution of the human path and long-term treatment of serial killers remain rarely documented available in the literature.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genotyping strategies for tissues fixed with various embalming fluids for human identification, databasing, and traceability. 用各种防腐液固定的组织的基因分型策略，用于人类识别、数据库和可追溯性。

Journal of forensic sciences Pub Date : 2023-10-31 DOI: 10.1111/1556-4029.15414

Madeline Ashton, Natalia Czado, Michelle Harrel, Sheree Hughes

{"title":"Genotyping strategies for tissues fixed with various embalming fluids for human identification, databasing, and traceability.","authors":"Madeline Ashton, Natalia Czado, Michelle Harrel, Sheree Hughes","doi":"10.1111/1556-4029.15414","DOIUrl":"10.1111/1556-4029.15414","url":null,"abstract":"Within anatomical willed body programs and skeletal collections, whole bodies and their disassociated limbs and organs are identified and tracked. However, if these tracking mechanisms fail, DNA recovered from the formalin-fixed tissues/organs could provide an additional layer of quality assurance. Embalming fluids preserve biological tissues; however, they also damage, fragment, and cross-link DNA and protein molecules. This project investigated the success of STR-typing from various soft tissue and bone samples that were fixed with embalming solutions with a range of formaldehyde concentrations. Formalin-fixed samples dissected from five cadavers, including skin, muscle, bone, heart, and kidney were used in Phase 1 of this study. In Phase 2, an additional 57 tissue samples from various embalmed organs and body parts were collected to demonstrate long-term fixation and direct applicability within a body donor program. DNA was extracted from the samples using the QIAamp® FFPE Tissue Kit (QIAGEN), quantified with the Investigator® QuantiPlex® Pro RGQ qPCR Kit (QIAGEN), and amplified using the Investigator® 24plex and 26plex QS Kits and the Investigator® DIPplex Kit (QIAGEN). The results show the DNA was severely damaged, degraded, and often in low amounts (after one year post-embalming). Sampling from skin and muscle tissues embalmed with ~2.5%-5% formaldehyde solutions appears to be the best strategy for identification, while also maintaining the preservation of the tissues. The results of this project can provide informative data when determining which genotyping strategy may be best suited for the identification, re-association, and establishment of a database for the provenance of formalin-fixed human remains.","PeriodicalId":94080,"journal":{"name":"Journal of forensic sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71416309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0