Journal of biophotonics最新文献

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Optimized reconstruction of the absorption spectra of kidney tissues from the spectra of tissue components using the least squares method. 利用最小二乘法从组织成分的光谱中优化重建肾脏组织的吸收光谱。

Journal of biophotonics Pub Date : 2024-02-06 DOI: 10.1002/jbio.202300466

Maria R Pinheiro, Luís E Fernandes, Isa C Carneiro, Sónia D Carvalho, Rui M Henrique, Valery V Tuchin, Hélder P Oliveira, Luís M Oliveira

{"title":"Optimized reconstruction of the absorption spectra of kidney tissues from the spectra of tissue components using the least squares method.","authors":"Maria R Pinheiro, Luís E Fernandes, Isa C Carneiro, Sónia D Carvalho, Rui M Henrique, Valery V Tuchin, Hélder P Oliveira, Luís M Oliveira","doi":"10.1002/jbio.202300466","DOIUrl":"https://doi.org/10.1002/jbio.202300466","url":null,"abstract":"With the objective of developing new methods to acquire diagnostic information, the reconstruction of the broadband absorption coefficient spectra (μa [λ]) of healthy and chromophobe renal cell carcinoma kidney tissues was performed. By performing a weighted sum of the absorption spectra of proteins, DNA, oxygenated, and deoxygenated hemoglobin, lipids, water, melanin, and lipofuscin, it was possible to obtain a good match of the experimental μa (λ) of both kidney conditions. The weights used in those reconstructions were estimated using the least squares method, and assuming a total water content of 77% in both kidney tissues, it was possible to calculate the concentrations of the other tissue components. It has been shown that with the development of cancer, the concentrations of proteins, DNA, oxygenated hemoglobin, lipids, and lipofuscin increase, and the concentration of melanin decreases. Future studies based on minimally invasive spectral measurements will allow cancer diagnosis using the proposed approach.","PeriodicalId":94068,"journal":{"name":"Journal of biophotonics","volume":" ","pages":"e202300466"},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139693674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Smartphone-based detection of COVID-19 and associated pneumonia using thermal imaging and a transfer learning algorithm. 利用热成像和迁移学习算法，基于智能手机检测 COVID-19 和相关肺炎。

Journal of biophotonics Pub Date : 2024-01-22 DOI: 10.1002/jbio.202300486

Oshrit Hoffer, Rafael Y Brzezinski, Adam Ganim, Perry Shalom, Zehava Ovadia-Blechman, Lital Ben-Baruch, Nir Lewis, Racheli Peled, Carmi Shimon, Nili Naftali-Shani, Eyal Katz, Yair Zimmer, Neta Rabin

引用次数: 0

Impact of e-cigarette liquid on porcine lung tissue-Ex vivo confocal Raman micro-spectroscopy study. 电子烟液体对猪肺组织的影响——离体共聚焦拉曼显微光谱研究。

Journal of biophotonics Pub Date : 2023-10-18 DOI: 10.1002/jbio.202300336

Ali Jaafar, Abbas Albarazanchi, Mohammed Jawad Kadhim, Maxim E Darvin, Tamás Váczi, Valery V Tuchin, Miklós Veres

{"title":"Impact of e-cigarette liquid on porcine lung tissue-Ex vivo confocal Raman micro-spectroscopy study.","authors":"Ali Jaafar, Abbas Albarazanchi, Mohammed Jawad Kadhim, Maxim E Darvin, Tamás Váczi, Valery V Tuchin, Miklós Veres","doi":"10.1002/jbio.202300336","DOIUrl":"10.1002/jbio.202300336","url":null,"abstract":"Ex vivo porcine lung immersed in e-liquid was investigated in-depth using confocal Raman micro-spectroscopy to assess the e-liquid influence on the lung. It was found that lung-related Raman band intensities at 1002, 1548, 1618 and 1655 cm-1 increased after first and second treatments except the surface, which was attributed to the well-known optical clearing (OC) effect due to alveoli filling with e-liquid resulting in light scattering reduction. The autofluorescence enhancement was explained by oxidative stress induced in lung during exposure to e-liquid. Moreover, e-liquid induced collagen dehydration was revealed by the I937 /I926 Raman band intensity ratio change. The effect was enhanced after the second treatment of the same lung tissue that indicates the possibility of multi-step OC treatment. We hypothesize that the nicotine-flavour-free e-liquids containing glycerol and propylene glycol could potentially be used in clinical protocols as OC agent for enhanced in-depth Raman-guided bronchoscopy.","PeriodicalId":94068,"journal":{"name":"Journal of biophotonics","volume":" ","pages":"e202300336"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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