Frontiers in oral health最新文献

{"title":"Conventional scan body vs. scan bodies with auxiliary geometric devices: an <i>in vitro</i> study for edentulous full-arch implant impressions.","authors":"Francesco Gianfreda, Carlo Raffone, Mirko Martelli, Alberto Pitino, Vito Carlo Alberto Caponio, Patrizio Bollero","doi":"10.3389/froh.2025.1574149","DOIUrl":"10.3389/froh.2025.1574149","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to assess the effectiveness of an auxiliary geometric device (AGD) in enhancing the trueness of full-arch implant impressions. The primary metrics of interest were total surface deviation (TotRMS), centroid deviation (cRMS), and angular deviation. All these values are crucial for achieving a precise fit of implant-supported prostheses.</p><p><strong>Methods: </strong>A gypsum-based edentulous maxillary model with four multi-unit abutment replicas was prepared, replicating clinical scenarios. Control and experimental scan bodies were scanned using an intraoral scanner (Dexis 3800), and the resulting data were compared to a digital master model created with a structured light scanner (ATOS compact Scan 5M). The AGD was used to reduce positional errors during the scan process. Data were processed using Exocad and GOM Inspect Professional software, aligning scan body library files with mesh data using a best-fit algorithm. Angular, platform, and total deviations were calculated to assess positional trueness. A sample size of 20 scans per group was determined <i>a priori</i>, and statistical comparisons were made using Mann-Whitney <i>U</i> tests.</p><p><strong>Results: </strong>The inclusion of the AGD significantly reduced centroid root mean square (cRMS) values in all measured comparisons (<i>p</i> < 0.001), demonstrating enhanced trueness. The total body root mean square deviation <b>(</b>TotRMS) values also showed a significant reduction (<i>p</i> = 0.002). While overall angular deviation differences were not statistically significant (meanAGD = 0.38; meanNO = 0.39; where \"NO\" refers to the group without AGD), site-specific analysis revealed significant improvements at points 2.4 (<i>p</i> = 0.017) and 1.4 (<i>p</i> < 0.001). The Euclidean distance in platform deviation consistently indicated better alignment in the AGD group.</p><p><strong>Conclusion: </strong>The AGD, tested under <i>in vitro</i> conditions, significantly improved the trueness of full-arch implant impressions, particularly reducing c- and TotRMS values. These findings highlight the AGD's potential to enhance digital workflows in implant dentistry by mitigating positional discrepancies and ensuring greater trueness and precision. Future research should explore these findings in a clinical scenario.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1574149"},"PeriodicalIF":3.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of a carbonated beverage on the optical properties and microhardness of preheated bulk-fill composite resin restorations.","authors":"Nancy Soliman Farghal, Ayya Abu Shamleh, Osamah Al Hurmuzi, Okba Mahmoud","doi":"10.3389/froh.2025.1539527","DOIUrl":"10.3389/froh.2025.1539527","url":null,"abstract":"<p><strong>Introduction: </strong>Preheating the high-viscosity forms of bulk-fill resin composites is recommended to enhance their flow and adaptability. Nevertheless, the impact of preheating on their characteristics upon exposure to carbonated beverages remains unclear. This study aims to evaluate the effect of a Cola beverage on the properties of preheated and non-preheated high-viscosity bulk-fill composite resins <i>in vitro</i>.</p><p><strong>Methods: </strong>Forty disc-shaped specimens were prepared from each of BEAUTIFIL-Bulk Restorative (BB) and Filtek One Bulk-fill (FOB) composite resin, then divided into two groups (<i>n</i> = 20), either preheated to 68°C for 15 min or kept at room temperature before polymerization, then specimens were immersed in Alkozay Cola beverage for 30 days (3 periods of 15 min/day). Color stability (ΔE₀₀), surface gloss (GU) and Vickers Microhardness (VHN) were recorded before and after the Cola immersion. The data was analyzed with Two-way ANOVA, Three-way ANOVA and Tukey's HSD <i>post hoc</i> test using SPSS software at 95% significance level.</p><p><strong>Results: </strong>The color change was significantly higher in BB than FOB in all groups (<i>P</i> < 0:001), FOB had a significant reduction in color change after preheating (<i>P</i> < 0.05) while BB had no significant change (<i>P</i> > 0.05). Preheating significantly increased the gloss of BB and reduced that of FOB (<i>P</i> < 0.001), however, Cola beverage significantly reduced the gloss of all the groups (<i>P</i> < 0.001). Preheating significantly increased the microhardness of both materials (<i>P</i> < 0.001), however, Cola beverage significantly reduced the microhardness of all the groups (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Although the preheating of high-viscosity bulk-fill composites significantly improved their microhardness and improved the surface gloss of FOB, it did not protect both composites against the Cola drink attack. Preheated FOB showed improved color stability after the Cola immersion, but not to a clinically acceptable limit.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1539527"},"PeriodicalIF":3.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bibliometric and visualization analysis of temporomandibular joint osteoarthritis from 2004 to 2024.","authors":"Chi Xu, Chongqing Yu, Tao Wang, Xiang Gao","doi":"10.3389/froh.2025.1596551","DOIUrl":"10.3389/froh.2025.1596551","url":null,"abstract":"<p><strong>Background: </strong>Temporomandibular joint osteoarthritis (TMJOA) is a severe condition affecting the temporomandibular joint, impairing essential oral functions such as chewing, speaking, and swallowing. Recent studies have made significant outcomes in pathogenesis, clinical symptoms, and therapy in the field of TMJOA. However, knowledge of research trends and hotspots of TMJOA is still lacking in this field. This study conducted a bibliometric analysis of TMJOA, providing a comprehensive overview of current research hotspots and trends.</p><p><strong>Methods: </strong>A total of 584 TMJOA-related records published between 2004 and 2024 were retrieved from the Web of Science Core Collection (WoSCC) database. VOSviewer, CiteSpace, the R package \"bibliometrix\", and the Bibliometric website were used to analyze countries, institutions, journals, authors, and keywords to identify research trends in TMJOA.</p><p><strong>Results: </strong>Publications on TMJOA have shown a steady annual increase. Globally, China and the USA emerged as the leading contributors, accounting for over 60% of the publications. Sichuan University ranked first in total publications and citations, while the University of Northern Carolina led in average citations. The <i>Journal of Oral Rehabilitation</i> published the most studies, whereas the <i>Journal of Dental Research</i> had the highest impact factor (5.3) and H-index (158). Long X was the most prolific author, while Liu Y, Manfredini D, and Guarda-Narnini L were the top-cited authors with the highest H-indices. Keyword analysis revealed four primary research clusters: \"pathogenesis mechanisms\", \"clinical manifestations\", \"regeneration research\", and \"therapy research\".</p><p><strong>Conclusion: </strong>This bibliometric analysis highlights publication trends, research hotspots, citation patterns, and collaborative networks among countries, institutions, and authors in the TMJOA field. Future research is expected to focus on molecular signaling pathways and targeted therapies for TMJOA, with the ultimate goal of accelerating translational research to enhance clinical outcomes for patients.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1596551"},"PeriodicalIF":3.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of pomegranate extract on preventing dental caries: a systematic review.","authors":"Niyousha Rafeie, Yasaman Salimi, Zahra Sadat Aghamir, Amirhesam Amini, Hamed Taheri, Sarvin Sadreddini, Fatemeh Kamali, Golnesa Akbarian, Nazanin Azizi, Mobina Bagherianlemraski, Maryam Valizadeh, Farnoosh Alimohammadi, Negar Sedighnia, Mohammad Qadirifard, Mahdyieh Naziri","doi":"10.3389/froh.2025.1484364","DOIUrl":"10.3389/froh.2025.1484364","url":null,"abstract":"<p><strong>Background/purpose: </strong>The present study aimed to evaluate the effect of pomegranate extract on the prevention of dental caries compared to standard care, placebo, and no intervention.</p><p><strong>Materials and methods: </strong>A bibliographic search in four databases, including PubMed, Scopus, Google Scholar, and CENTRAL, yielded 291 studies until September 8, 2023. The search was performed among the studies written in English using the search terms \"<i>Punica granatum</i>\" AND (\"dental caries\" OR \"<i>Streptococcus mutans</i>\" OR \"tooth demineralization\") After screening the titles/abstracts and full texts of these studies, 7 articles were chosen.</p><p><strong>Results: </strong>In all 7 articles, pomegranate mouthwash was used as the intervention. In 5 studies, the control group used 0.2% chlorhexidine (CHX) mouthwash. Additionally, 4 articles reported a reduction in the mean <i>Streptococcus mutans</i> plaque count in both groups; however, better results were observed in the CHX mouthwash group. In one study, no significant difference was reported between the study and control groups. Finally, one study showed the significant superiority of a hydroalcoholic extract of pomegranate mouthwash over CHX mouthwash.</p><p><strong>Conclusion: </strong>Overall, the results suggest that pomegranate extract mouthwash is highly effective in reducing caries-causing bacteria. No side effects were reported for pomegranate use in these studies.</p><p><strong>Systematic review registration: </strong>https://osf.io/69gpc/.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1484364"},"PeriodicalIF":3.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12148722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impacts of oral health on life quality metrics: correlations with job function, psychological well-being, self-perception, and dietary behavior.","authors":"Mohammad Helmi","doi":"10.3389/froh.2025.1586868","DOIUrl":"10.3389/froh.2025.1586868","url":null,"abstract":"<p><strong>Introduction: </strong>This study evaluates the impact of oral health issues on critical areas of daily functioning, including job performance, psychological well-being, self-rated oral health, and dietary habits.</p><p><strong>Methods: </strong>Utilizing NHANES data, the analysis applies Pearson correlation, multiple regression, and data visualization techniques (scatter plots, heatmaps, and box plots) to quantify associations between oral health variables, such as mouth aching (OHQ620), food avoidance (OHQ660), job difficulty due to mouth issues (OHQ640), and embarrassment (OHQ680).</p><p><strong>Results: </strong>Strong correlations were found between mouth aching and job difficulty due to mouth issues, with a Pearson correlation coefficient of 0.99, and between difficulty eating (OHQ670) and job difficulty due to mouth issues, with a coefficient of 0.98. Psychological impacts were also notable; feeling bad about one's mouth (OHQ630) had a high correlation with embarrassment (0.99), while mouth aching had a weaker association (0.88). Self-rated oral health (OHQ845) showed a negative correlation with both mouth aching (-0.83) and feeling bad about one's mouth (-0.83), indicating decreased self-assessment of oral health as symptoms increase. Multiple regression revealed that difficulty eating had a substantial positive coefficient (1.19) for food avoidance, while mouth aching had a minor negative effect (-0.13). Smoking exposure was positively associated with oral health issues, particularly with mouth aching and embarrassment.</p><p><strong>Conclusions: </strong>The findings highlight significant impacts of oral health issues on job performance, psychological well-being, and lifestyle, suggesting the need for integrated oral healthcare strategies that address both physical discomfort and emotional consequences.</p><p><strong>Practical implications: </strong>Enhanced oral health interventions focusing on symptom management and psychological support could reduce nutrition barriers, improve occupational functioning, and increase quality of life.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1586868"},"PeriodicalIF":3.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral health-related quality of life in patients with periodontitis: a systematic review and meta-analysis.","authors":"Joanna Slowik, Anna Panasiuk, Marcin Kaczor, Marcin Wnuk","doi":"10.3389/froh.2025.1503829","DOIUrl":"10.3389/froh.2025.1503829","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to comprehensively evaluate the impact of periodontitis on Oral Health-Related Quality of Life (OHRQoL) using the OHIP-14 questionnaire. A quantitative meta-analysis was conducted to estimate the average effect size, taking into account the characteristics of periodontitis and the features of control groups. Additionally, associations between OHRQoL and periodontitis were explored based on participant demographics and clinical factors.</p><p><strong>Methods: </strong>We systematically searched the PubMed, Embase, and Scopus databases up to March 8, 2024. Studies included in the analysis assessed OHRQoL in patients with periodontitis (exposed group) compared to non-periodontitis individuals (non-exposed control group). A valid periodontitis diagnosis required Clinical Attachment Loss (CAL) and Pocket Probing Depth (PPD) assessments during full-mouth clinical examinations. The choice of meta-analysis model was based on an assessment of heterogeneity. The quality of the included studies was assessed using the tool developed by The National Heart, Lung, and Blood Institute (<i>N</i>HLBI).</p><p><strong>Results: </strong>Nine studies, encompassing 2,287 individuals, met the inclusion criteria. Periodontitis significantly affected the mean OHIP-14 total scores compared to controls [Weighted Mean Differences WMD random = 6.11 (95% CI: 4.23, 7.99), <i>p</i> < 0.0001], with substantial heterogeneity. Subgroup analysis did not reveal significant regional variations. Restricting the analysis to studies using the American Academy of Periodontology/European Federation of Periodontology consensus definition from 2017 yielded similar results. The negative impact of periodontitis on OHRQoL was associated with disease severity and female sex but was not influenced by the region or age of the study participants.</p><p><strong>Conclusions: </strong>Our findings confirm that periodontitis significantly impairs OHRQoL, with potential associations related to disease severity and sex. However, the limited availability of studies with matched control groups and poor data reporting quality constrains a more comprehensive assessment.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1503829"},"PeriodicalIF":3.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12146335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visualization of oral function during playing a wind instrument by a lateral dental impression: a proof-of-concept investigation.","authors":"Mariko Hattori, Gen Tanabe, Sebastian B M Patzelt, Dirk Schulze, Yuka I Sumita, Noriyuki Wakabayashi","doi":"10.3389/froh.2025.1522642","DOIUrl":"10.3389/froh.2025.1522642","url":null,"abstract":"<p><p>Embouchure describes the interaction of the teeth, lips, tongue, buccal mucosa, and surrounding muscles when playing woodwind and brass instruments. In dental practice, impression material is used to capture the oral structure and function. In this proof-of-concept investigation, embouchure was examined using a silicone-based dental impression material. The participants were 1 oboe player, 1 alto saxophone player, and 4 tenor saxophone players. Four of the participants were amateurs and 2 were professionals. The dental impression material was mixed and inserted onto the buccal aspect of the upper molars. The musicians blew test tones and maintained embouchure for 30 s while a lateral embouchure impression was taken. The hardened material was removed and scanned using cone-beam computed tomography. The three-dimensional surface data of the impression were exported, and the mean thickness was analyzed. The impressions showed the space between the alveolar and buccal mucosae. The mean thickness ± standard deviation of the impressions was 2.35 ± 0.85 mm. The oboist showed the smallest thickness, while the tenor saxophonists showed the greatest thickness. The method enabled visualization of the unique morphology of each participant. The results suggest that embouchure can be objectively evaluated using the presented technique. Making embouchure impressions to assess oral problems should enable dentists to evaluate changes in music playing resulting from oral problems or for their treatment. Further studies in a larger population are needed to generalize the results.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1522642"},"PeriodicalIF":3.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12146393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyaluronic acid as a promoter of the healing of post-extraction socket treated with the socket preservation technique: a systematic review.","authors":"Tommaso Pizzolante, Gianluca Benincasa, Francesco Bizzarro, Mario Capogreco, Enrico Marchetti","doi":"10.3389/froh.2025.1583189","DOIUrl":"10.3389/froh.2025.1583189","url":null,"abstract":"<p><strong>Background: </strong>This review examines the role of hyaluronic acid (HA) in enhancing the healing of the post-extraction socket. HA, a naturally occurring glycosaminoglycan in the extracellular matrix, is crucial for wound healing. It promotes tissue repair by stimulating cell migration, adhesion, and proliferation, essential for bone formation. When combined with deproteinized bovine bone mineral (DBBM), HA may improve bone regeneration and reduce resorption, though evidence is still limited.</p><p><strong>Methods: </strong>Three clinical studies were reviewed, assessing primary outcomes such as volumetric bone resorption, linear bone loss, and soft tissue healing. Radiographic evaluations, including cone beam computed tomography (CBCT), were used to quantify bone changes, while clinical assessments were conducted to evaluate soft tissue responses and wound healing over a 4-month follow-up period.</p><p><strong>Results: </strong>Two studies demonstrated that HA, in combination with DBBM, significantly improved bone preservation. These studies found reduced volumetric bone resorption and enhanced bone width retention, with one showing a significant reduction in crestal bone loss (<i>p</i> < 0.001). In contrast, the third study did not report any significant improvements in soft tissue healing or bone preservation with HA treatment.</p><p><strong>Conclusions: </strong>The results of this review suggest that HA, combined with DBBM, may offer significant benefits in reducing bone resorption and preserving bone width in ARP procedures. However, the impact of HA on soft tissue healing cannot yet be statistically evaluated, highlighting the need for further investigation to optimize its use in clinical practice.</p><p><strong>Systematic review registration: </strong>https://www.crd.york.ac.uk/PROSPERO/view/CRD42024526628, PROSPERO CRD42024526628.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1583189"},"PeriodicalIF":3.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12146101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Walking in a dental environment with the \"UniCDent\" tool kit-part 1: a participatory tool with legs!","authors":"Prashanti Eachempati, John Martin, Sally Hanks, Mona Nasser","doi":"10.3389/froh.2025.1545170","DOIUrl":"10.3389/froh.2025.1545170","url":null,"abstract":"<p><p>This case study explores the adaptation of the walking method coupled with auto-photography and photo elicitation, a participatory research tool traditionally used in landscape studies, for application in dental research settings. By presenting the UniCDent toolkit, we demonstrate how this immersive method can enhance understanding of patient experiences in dentistry through sensory engagement and spatial exploration. The toolkit comprises four components: Imagery, Gallery Walk, Quadrant Mapping, and Trade-offs, each designed to facilitate active participation and foster in-depth reflections on the dental environment. Participants navigate a simulated dental clinic, documenting their sensory experiences and social interactions, thereby enriching the data collected. This multi-layered approach allows researchers to capture the complexities of patient experiences, providing insights that are applicable across various research projects within dentistry. The commentary highlights the versatility of the walking method, emphasising its role in improving patient-centred care by capturing patient experiences and perspectives. It also demonstrates its value in enhancing the understanding of diverse research enquiries in dental research.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1545170"},"PeriodicalIF":3.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Redondovirius-associated periodontitis in people with poor oral hygiene: a cross-sectional study.","authors":"Alireza Mohebbi, Zakiyeh Donyavi, Zoleikha Mamizadeh, Khadijeh Khanaliha, Nikoo Emtiazi, Seyed Jalal Kiani, Tahereh Donyavi, Alireza Shadab, Roghayeh Babaei, Farah Bokharaei-Salim","doi":"10.3389/froh.2025.1572274","DOIUrl":"10.3389/froh.2025.1572274","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the prevalence of recently emerged members of the <i>Redondoviridae</i> family (ReDoVs) in individuals with periodontitis.</p><p><strong>Methods: </strong>This study involved real-world data from 230 participants, 115 with chronic periodontitis and an independent population consisting of 115 participants with oral hygiene habits selected from the refferals, and approved by the experts from October 2023 to May 2024. Demographic, health-related, and behavioral data were collected. Gingival samples were analyzed for ReDoVs using polymerase chain reaction (PCR), followed by sequencing and phylogenetic analysis.</p><p><strong>Results: </strong>ReDoVs were detected in 51.30% of the periodontitis group and 21.74% of the other groups with oral hygiene habits (<i>p</i> < 0.0001). ReDoV presence was associated with a lack of teeth-brushing habits (<i>p</i> < 0.05). Furthermore, flossing was negatively correlated with reduced ReDoV genomes (<i>r</i> = -0.20, <i>p</i> = 0.03).</p><p><strong>Conclusions: </strong>ReDoVs and periodontitis were associated with adults with poor dental hygiene. This supports a possible multifactorial and complex interaction between the presence of ReDoVs and periodontitis. Also, the findings of this study highlight that poor oral hygiene increases the likelihood of ReDoV presence and suggests that factors such as flossing are predictors of ReDoV infections.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1572274"},"PeriodicalIF":3.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12142335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}