Frontiers in oral health最新文献

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Influence of odontogenic lesions on root development in impacted teeth: a cohort study. 牙源性病变对阻生牙根发育的影响:一项队列研究。
IF 3.1
Frontiers in oral health Pub Date : 2025-08-18 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1634188
Selene Barone, Alessandro Antonelli, Antonio Madonna, Vincenzo Greco, Massimo Borelli, Francesco Bennardo, Amerigo Giudice, Lucia Cevidanes
{"title":"Influence of odontogenic lesions on root development in impacted teeth: a cohort study.","authors":"Selene Barone, Alessandro Antonelli, Antonio Madonna, Vincenzo Greco, Massimo Borelli, Francesco Bennardo, Amerigo Giudice, Lucia Cevidanes","doi":"10.3389/froh.2025.1634188","DOIUrl":"10.3389/froh.2025.1634188","url":null,"abstract":"<p><strong>Introduction: </strong>Root dilaceration, a clinically significant developmental anomaly that can complicate dental treatment, has been attributed to various etiological factors, but the role of odontogenic lesions is still poorly understood. This observational study aimed to evaluate the relationship between odontogenic lesions and root dilaceration in impacted teeth.</p><p><strong>Methods: </strong>The sample size consisted of 22 impacted teeth divided into two groups: with odontogenic lesions (Group IwL) and without lesions (Group IwoL). Pre- and post-treatment radiographs, taken before and after conservative surgical or orthodontic-surgical management of impacted teeth, were used to assess the occurrence of dilaceration in both groups. Fisher's exact text was applied to compare the prevalence of dilaceration in both groups. In order to analyze the influence of each additional variable on dilaceration, a multivariate analysis was performed through logistic regression.</p><p><strong>Results: </strong>Root dilaceration was significantly more common in Group IwL (72.73%) than in Group IwoL (18.18%) (<i>p</i> = 0.030). No significant association was found between root dilaceration and additional variables, including impaction depth, cortical bone contact, maximum lesion size, and lesion volume.</p><p><strong>Conclusions: </strong>This study provides novel evidence for a correlation between odontogenic lesions and root dilaceration, suggesting that compressive forces from these lesions may significantly contribute to abnormal root development, with important implications for clinical diagnosis and treatment planning.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1634188"},"PeriodicalIF":3.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12399650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparative analysis of perceptions and evaluations of Simodont® Dental Trainer: a decade of virtual simulation. simmodon®牙科培训师的认知和评价的比较分析:十年的虚拟模拟。
IF 3.1
Frontiers in oral health Pub Date : 2025-08-18 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1646299
Mahmoud M Bakr, Andrew Cameron, Ghassan Idris, Mohamed Shamel, Mahmoud Al Ankily
{"title":"A comparative analysis of perceptions and evaluations of Simodont® Dental Trainer: a decade of virtual simulation.","authors":"Mahmoud M Bakr, Andrew Cameron, Ghassan Idris, Mohamed Shamel, Mahmoud Al Ankily","doi":"10.3389/froh.2025.1646299","DOIUrl":"10.3389/froh.2025.1646299","url":null,"abstract":"<p><strong>Introduction/background: </strong>Virtual dental simulators with a haptics component have been used with great success in dental education for over a decade and is becoming an integral part of dental curricula. A large number of studies have been published about the users' perception, acceptance and attitude towards virtual dental simulators. However, no longitudinal or long-term studies to our knowledge have been conducted to evaluate the users' acceptance over time.</p><p><strong>Aims and objectives: </strong>The aim of the present study is to compare the students' and academic staff's perceptions and expectations before using the Simodont® Dental Trainer and their evaluation of the technology after using it now vs. ten years ago.</p><p><strong>Materials and methods: </strong>The participants were invited for a trial session on the Simodont® Dental Trainer and were asked to evaluate different aspects of this virtual simulator by completing a pre-experimental and post-experimental questionnaire. The data collected from the current study was compared against similar data collected and published a decade ago in the same educational institution.</p><p><strong>Results: </strong>In general, participants from the present study rated different aspects of Simodont® dental trainer higher than their counterparts from the previous study a decade ago. Students from the present study were more excited and more likely to accept the technology when compared to the academic staff members as well as their counterparts from the 2014 student cohort. Academic staff and students from both studies were in total agreement that the Simodont® dental trainer should not be replacing traditional teaching. Both cohorts agreed that the feedback provided by the simulator should be supplemented by feedback from human supervisors. The open-ended responses highlighted the cost-effectiveness, student engagement, value of accessibility and flexibility in virtual dental training as well as persistent technical issues within the software as well as the need to develop more didactic content alongside the practical tasks offered by the simulator.</p><p><strong>Conclusion: </strong>Generational differences as well as technology limitations affect the perception to virtual dental simulation. The acceptance of the Simodont® dental trainer is following the cycle of technology adoption models.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1646299"},"PeriodicalIF":3.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12399597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brush, byte, and bot: quality comparison of artificial intelligence-generated pediatric dental advice across ChatGPT, Gemini, and Copilot. 刷、字节和机器人:ChatGPT、Gemini和Copilot中人工智能生成的儿科牙科建议的质量比较。
IF 3.1
Frontiers in oral health Pub Date : 2025-08-15 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1652422
Deepika Kapoor, Deepanshu Garg, Santosh Kumar Tadakamadla
{"title":"Brush, byte, and bot: quality comparison of artificial intelligence-generated pediatric dental advice across ChatGPT, Gemini, and Copilot.","authors":"Deepika Kapoor, Deepanshu Garg, Santosh Kumar Tadakamadla","doi":"10.3389/froh.2025.1652422","DOIUrl":"10.3389/froh.2025.1652422","url":null,"abstract":"<p><strong>Introduction: </strong>Artificial intelligence (AI) tools such as ChatGPT, Google Gemini, and Microsoft Copilot are increasingly relied upon by parents for immediate guidance on pediatric dental concerns. This study evaluated and compared the response quality of these AI platforms in addressing real-world parental queries related to pediatric dentistry, including early tooth extraction, space maintenance, and the decision to consult a pediatric or a general dentist.</p><p><strong>Methods: </strong>A structured 30-question survey was developed and submitted to each AI model, and their responses were anonymized and assessed by pediatric dental experts using a standardized rubric across five key domains: clinical accuracy, clarity, completeness, relevance, and absence of misleading information.</p><p><strong>Results: </strong>Statistically significant differences were found across all five domains (<i>p</i> < .001), with ChatGPT consistently achieving the highest scores. Multivariate analysis (MANOVA) confirmed a strong overall effect of the AI model on response quality (Pillai's Trace = 0.892, <i>p</i> < .001), supporting ChatGPT's superior performance in providing accurate, relevant, and comprehensive pediatric dental advice.</p><p><strong>Discussion: </strong>While AI technologies show potential as clinical decision support systems, their variable performance reinforces the need for expert oversight. Future AI development should focus on optimizing response quality and safety to ensure effective and trustworthy digital health communication for pediatric dental care.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1652422"},"PeriodicalIF":3.1,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12394529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144983881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-viral alterations in periodontal health in individuals recovering from COVID-19. COVID-19恢复期患者牙周健康的病毒后改变
IF 3.1
Frontiers in oral health Pub Date : 2025-08-15 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1654029
Jelena Roganović, Milena Barać, Biljana Miličić, Milan Petrović, Stefan Sredojević, Ana Đinić Krasavčević, Nataša Nikolić-Jakoba
{"title":"Post-viral alterations in periodontal health in individuals recovering from COVID-19.","authors":"Jelena Roganović, Milena Barać, Biljana Miličić, Milan Petrović, Stefan Sredojević, Ana Đinić Krasavčević, Nataša Nikolić-Jakoba","doi":"10.3389/froh.2025.1654029","DOIUrl":"10.3389/froh.2025.1654029","url":null,"abstract":"<p><p>This study explores post-viral immune modulation in periodontal health using COVID-19 convalescence as a model. We hypothesized that post-COVID-19 recovery induces epigenetic alterations, measurable through salivary methyl-transferase-like 3 (METTL3) expression and clinical-periodontal parameters. The present research comprises results from two studies: the clinical study, which included a total of 83 systemically healthy adults stratified into four groups according to periodontal status and COVID-19 history, and the laboratory study on human parotid gland samples (<i>n</i> = 10). Full-mouth periodontal status and unstimulated morning saliva were obtained. Glandular METTL3 and fat mass and obesity-associated factor as well as salivary METTL3 and cortisol were quantified using ELISA; psychological stress was assessed with the Perceived Stress Scale -10. Effect sizes were assessed using ANOVA and multivariable linear regression, and receiver operating characteristic (ROC) curves were generated for METTL3. Decreased levels of METTL3 in parotid tissue and in saliva of COVID-19 convalescents were found. Prior COVID-19 was significantly associated with METTL3 and plaque index (PI) as predictors, when adjusted for age, gender, periodontitis, and salivary cortisol. Strong associations between METTL3 and PI were found. Stress scores and cortisol did not differ between groups. Thus, downregulation of salivary METTL3 and concomitant plaque index reduction characterize the late convalescent phase of COVID-19. These epigenetic changes may reflect post-viral changes in parotid gland and periodontal health homeostasis and warrant longitudinal research confirmation.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1654029"},"PeriodicalIF":3.1,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145014864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship of stress level and periodontal tissue health in soldiers from Kodam Jaya: a cross-sectional study. 科丹加亚士兵应激水平与牙周组织健康的关系:一项横断面研究。
IF 3.1
Frontiers in oral health Pub Date : 2025-08-15 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1574112
Baby Prabowo Setyawati, Nadila Dita, Ishiko Herianto, Ernie Maduratna Setiawatie
{"title":"The relationship of stress level and periodontal tissue health in soldiers from Kodam Jaya: a cross-sectional study.","authors":"Baby Prabowo Setyawati, Nadila Dita, Ishiko Herianto, Ernie Maduratna Setiawatie","doi":"10.3389/froh.2025.1574112","DOIUrl":"10.3389/froh.2025.1574112","url":null,"abstract":"<p><strong>Background: </strong>Stress plays a crucial role in the development of periodontal diseases, along with other behavioral factors. Professions with high-stress levels, like the Indonesian National Army, face challenges due to demanding requirements on skills, physical endurance, and mental strength. This study aims to explore the oral and periodontal health of soldiers, with a focus on the relationship between stress levels and periodontal conditions in soldiers from Kodam Jaya.</p><p><strong>Methods: </strong>The research method is observational with a cross-sectional approach involving 48 male respondents selected using a purposive sampling technique. All participants completed ten closed-ended questionnaires about emotions and thoughts over the past month, along with the Perceived Stress Scale (PSS). Data processing was analyzed using univariate and bivariate methods, including Spearman's correlation.</p><p><strong>Results: </strong>The analysis of stress levels among soldiers shows that the light category includes 11 individuals (22.9%), the moderate category consists of 29 individuals (60.4%), and the heavy category includes 8 individuals (16.7%). Therefore, out of the total 48 responses, the moderate stress level is the most common among soldiers. In terms of the distribution of BoP examinations, 7 cases (14.6%) met the healthy criteria, 2 cases (4.2%) met the mild criteria, 5 cases (10.4%) met the moderate criteria, and 34 cases (70.8%) met the severe criteria. The correlation between stress level and periodontal tissue health at BoP examination shows a moderate relationship with an r-value of 0.407 and a <i>p</i>-value of 0.004, indicating a significant relationship.</p><p><strong>Conclusion: </strong>There is a notable link between stress and periodontal tissue health, along with the Bleeding on Probing (BoP) assessment, in soldiers from Kodam Jaya.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1574112"},"PeriodicalIF":3.1,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12394484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors of early childhood caries among preschool children in Shanghai, China: a longitudinal study. 上海学龄前儿童早期龋齿危险因素的纵向研究
IF 3.1
Frontiers in oral health Pub Date : 2025-08-14 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1635569
Yating Xu, Minyi Xu, Weihua Zhang, Xiping Feng, Jingyu Zhan, Yu Zhang, Xi Chen
{"title":"Risk factors of early childhood caries among preschool children in Shanghai, China: a longitudinal study.","authors":"Yating Xu, Minyi Xu, Weihua Zhang, Xiping Feng, Jingyu Zhan, Yu Zhang, Xi Chen","doi":"10.3389/froh.2025.1635569","DOIUrl":"10.3389/froh.2025.1635569","url":null,"abstract":"<p><strong>Introduction: </strong>Early childhood caries(ECC) has caused a growing public health burden worldwide, but there still remains a gap in the understanding of ECC in Shanghai, China. This study aims to investigate the current profile of ECC and related risk factors of new-onset caries among preschool children in Shanghai, China.</p><p><strong>Materials and methods: </strong>Children aged 3-5 were included in this two-year longitudinal study from Shanghai. Oral health information and related factors were collected through clinical examinations and questionnaires. Logistic and general linear regression were used to investigate the risk factors of early childhood caries. Ethical approval and informed consent form were achieved in the study.</p><p><strong>Results: </strong>A total of 192 children completed this 2-year longitudinal study with a follow-up rate of 80.0%. At follow-up, 70.8% of children developed new caries. The study revealed that children with lower mother's education level (<i>p</i> = 0.022), less father's income (<i>p</i> = 0.023), more frequent sugar intake (<i>p</i> = 0.006), and poor oral hygiene (<i>p</i> = 0.012) were more likely to develop new caries. Additionally, general linear regression demonstrated that children who did not use fluoride toothpaste (<i>p</i> = 0.006), those who consumed candy more (<i>p</i> = 0.028), and those with poor oral hygiene (<i>p</i> = 0.001) exhibited greater incremental caries.</p><p><strong>Conclusion: </strong>Lower father's income, lower mother's education level, frequent sugar consumption, non-use of fluoridated toothpaste, and poor oral hygiene status emerged as significant independent risk factors for ECC.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1635569"},"PeriodicalIF":3.1,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12391158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144983926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rescuing a "hopeless" tooth with severe internal resorption during orthodontic therapy: a case report. 正畸治疗中抢救一颗严重内吸收的“无望”牙齿1例。
IF 3.1
Frontiers in oral health Pub Date : 2025-08-14 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1604976
Wenjing Liu, Xuezhong Xu, Junqiang Wang, Zhidan Li
{"title":"Rescuing a \"hopeless\" tooth with severe internal resorption during orthodontic therapy: a case report.","authors":"Wenjing Liu, Xuezhong Xu, Junqiang Wang, Zhidan Li","doi":"10.3389/froh.2025.1604976","DOIUrl":"10.3389/froh.2025.1604976","url":null,"abstract":"<p><p>Root resorption is one of the leading complications that follows orthodontic treatment. It's an inflammatory process involving ischemic necrosis. Therefore, it is called orthodontically induced inflammatory root resorption (OIIRR). The purpose of this report is to present a case study of a patient in her 20s who experienced internal root resorption on two maxillary central incisors as a result of orthodontic treatment. Mineral trioxide aggregates (MTAs) were applied to the root resorption lesion to promote remineralization. A clinical and radiographic examination revealed that no radiolucency related to the resorptive lesion was found without any pathological symptoms after a 3-year follow-up.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1604976"},"PeriodicalIF":3.1,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12391063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144983952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Field cancerization in women without conventional risk factors: insights from a case-cohort study. 无传统危险因素的妇女现场癌变:来自病例队列研究的见解。
IF 3.1
Frontiers in oral health Pub Date : 2025-08-14 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1653210
Martina Coppini, Giuseppe Seminara, Rodolfo Mauceri, Olga Di Fede, Gaetano La Mantia, Nicola Mauceri, Valeria Cancila, Vito Rodolico, Giuseppina Campisi
{"title":"Field cancerization in women without conventional risk factors: insights from a case-cohort study.","authors":"Martina Coppini, Giuseppe Seminara, Rodolfo Mauceri, Olga Di Fede, Gaetano La Mantia, Nicola Mauceri, Valeria Cancila, Vito Rodolico, Giuseppina Campisi","doi":"10.3389/froh.2025.1653210","DOIUrl":"10.3389/froh.2025.1653210","url":null,"abstract":"<p><strong>Background: </strong>Field cancerization (FC) is a well-documented phenomenon in oral squamous cell carcinoma (OSCC), typically reported in patients with known risk habits such as tobacco and alcohol use. To date, limited evidence exists regarding FC in individuals without traditional carcinogenic exposures, as well as in those associated with chronic mechanical trauma. The study aims to report a case series of FC in patients without well-known risk habits observed in the last two years.</p><p><strong>Material and methods: </strong>This study is a retrospective cohort study conducted at the Unit of Oral Medicine \"V. Margiotta\" of the University Hospital \"Paolo Giaccone\" in Palermo (Italy). Between January 2023 and February 2025, a total of 64 patients affected by OSCC were observed. All cases were histologically confirmed through biopsy. For the present study, we focused specifically on the subgroup of patients who developed synchronous and/or metachronous lesions during this period.</p><p><strong>Results: </strong>A retrospective analysis was conducted on eight female patients (mean age: 75.5 ± 10.3 years) diagnosed with multifocal OSCC. Three patients presented with synchronous lesions, three with metachronous lesions, and two developed both types over time. Six patients (75%) were denture wearers.</p><p><strong>Conclusions: </strong>This study highlights the relevance of FC in elderly OSCC patients with no history of traditional carcinogenic exposures, except for the high prevalence of denture use, which, however, cannot be considered a clear causal factor. Long-term clinical and radiological surveillance is essential for early detection of multifocal lesions, thereby improving prognosis and patient quality of life.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1653210"},"PeriodicalIF":3.1,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12391006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144983887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Calcium, phosphate and fluoride ionic release from dental restorative materials for elderly population: an in vitro analysis. 老年人牙齿修复材料中钙、磷酸盐和氟化物离子释放的体外分析
IF 3.1
Frontiers in oral health Pub Date : 2025-08-11 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1609502
Angelo Aliberti, Franklin Garcia-Godoy, Alexandre Luiz Souto Borges, João Paulo Mendes Tribst, Roberta Gasparro, Mauro Mariniello, Pietro Ausiello
{"title":"Calcium, phosphate and fluoride ionic release from dental restorative materials for elderly population: an <i>in vitro</i> analysis.","authors":"Angelo Aliberti, Franklin Garcia-Godoy, Alexandre Luiz Souto Borges, João Paulo Mendes Tribst, Roberta Gasparro, Mauro Mariniello, Pietro Ausiello","doi":"10.3389/froh.2025.1609502","DOIUrl":"10.3389/froh.2025.1609502","url":null,"abstract":"<p><strong>Introduction: </strong>With the increasing prevalence of cervical and root lesions in elderly patients, dental filling materials able to release bioactive ions are gaining importance in the restorative treatment. This study evaluated the release of calcium (Ca<sup>2</sup> <sup>+</sup>), phosphate (PO<sub>4</sub> <sup>3-</sup>), and fluoride (F<sup>-</sup>) ions from different restorative materials (<i>Equia Forte HT Fil</i>, <i>Stela Self Cure</i> and <i>Riva Self Cure</i>) for elderly population through <i>in vitro</i> testing conducted under different pH levels and temperature conditions.</p><p><strong>Methods: </strong>Specimens (10 mm diameter and 2 mm thickness; <i>n</i> = 3 for each material) were prepared according to manufacturers' instructions, immersed in buffer solutions at pH 4.8, 6.8, and 8.8; and stored at 37°C and 44°C. Ion release was measured after 1-, 7-, and 28-days using ion chromatography (fluoride and phosphate ions) and mass spectrometry (calcium ions).</p><p><strong>Results: </strong>Ion release from dental restorative materials was significantly influenced by pH, temperature, and exposure duration. All materials tested exhibited consistent pH trends, with an increase in acidic conditions and stabilization in neutral and basic environments. Fluoride release was notably affected by pH and exposure time (<i>p</i> < 0.001), with <i>Equia Forte HT Fil</i> showing the highest fluoride release (34.59 ± 0.63 mg/L) in a basic environment at 37°C. <i>Stela Self Cure</i> had a maximum release of 3.55 ± 0.24 mg/L, and <i>Riva Self Cure</i> reached 7.67 ± 0.49 mg/L after 28 days at 44°C in an acidic medium. Phosphate release remained stable, while calcium ion release varied significantly among materials. <i>Stela Self Cure</i> had the highest calcium release (14.35 ± 0.45 mg/L) in a basic environment, and <i>Equia Forte HT Fil</i> showed the highest calcium concentration (30.60 ± 0.73 mg/L) in neutral conditions.</p><p><strong>Conclusions: </strong>The study highlights the relevance of ion-releasing from some bioactive dental restorative materials commonly employed also for managing Class V cervical lesions and promote remineralization in aging oral environments. Materials tested showed variable fluoride, calcium, and phosphate release depending on pH, temperature, and time. <i>Equia Forte HT Fil</i> and <i>Riva Self Cure</i> exhibited higher fluoride release, supporting anti-caries potential.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1609502"},"PeriodicalIF":3.1,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12375625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144983840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital granular cell epulis in a neonate: a case report and review of diagnosis, treatment, and prognosis. 新生儿先天性颗粒细胞脓包1例,诊断、治疗及预后回顾。
IF 3.1
Frontiers in oral health Pub Date : 2025-08-11 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1548291
P C Guidone, Roberta Seccia, L A Fabrocini, G Troiano, G Maffei, Maria Carmela Pedicillo, Giuseppe Pannone, Lorenzo Lo Muzio, Rosanna Zamparese, Giorgio Mori, Ilenia Sara De Stefano
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