Expert review of respiratory medicine最新文献_第8页

Harnessing music therapy and music medicine in chronic respiratory disease management. 利用音乐疗法和音乐医学治疗慢性呼吸系统疾病。

Expert review of respiratory medicine Pub Date : 2025-07-01 Epub Date: 2025-05-05 DOI: 10.1080/17476348.2025.2501279

Annemarie Louise Lee, Imogen Nicola Clark, Adam Lewis

{"title":"Harnessing music therapy and music medicine in chronic respiratory disease management.","authors":"Annemarie Louise Lee, Imogen Nicola Clark, Adam Lewis","doi":"10.1080/17476348.2025.2501279","DOIUrl":"10.1080/17476348.2025.2501279","url":null,"abstract":"Introduction: Treatment options for those living with chronic respiratory disease include non-pharmacological therapies to maximize outcomes. However, some individuals are limited by their symptoms, which inhibit their ability to benefit to an equivalent or expected level. Both music therapy and music medicine are therapeutic approaches which could address these limitations.Areas covered: This perspective reviews the clinical effects of music therapy and music medicine in chronic respiratory diseases. This considers active music therapy methods of re-creating (group singing), improvisation (instrument playing), receptive music listening and music medicine, with a specific focus at rest and during exercise.Expert commentary: The precise role of music therapy or music medicine as an adjunct to exercise testing or structured exercise programs for people with chronic respiratory disease is unclear. Choice of music (for background or individual use for this purpose) requires input from participants and would benefit from music therapists to guide selection. While preliminary findings of group singing and instrument playing highlight some efficacy, their role in comparison to pulmonary rehabilitation requires further clarification. At present, these music therapy and music medicine approaches can be considered as adjunct therapies which may assist in managing symptoms and improving wellbeing alongside existing management strategies.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"639-654"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unmet needs and future directions of treatment options for chronic cough. 慢性咳嗽治疗方案的未满足需求和未来方向。

Expert review of respiratory medicine Pub Date : 2025-07-01 Epub Date: 2025-04-29 DOI: 10.1080/17476348.2025.2499663

Mengru Zhang, Alyn Morice

{"title":"Unmet needs and future directions of treatment options for chronic cough.","authors":"Mengru Zhang, Alyn Morice","doi":"10.1080/17476348.2025.2499663","DOIUrl":"10.1080/17476348.2025.2499663","url":null,"abstract":"Introduction: Chronic cough is a persistent condition that significantly affects patients' quality of life and poses diagnostic and therapeutic challenges. Traditional anatomical diagnostic approaches often fail to address the underlying mechanisms, leading to suboptimal treatment outcomes.Area covered: This review aims to summarize the challenges of the management of chronic cough and highlights recent advances of several promising drug candidates in cough trials. PUBMED/CINAHL/Web of Science/Scopus were searched (February 2025).Expert opinion: Over the past 40 years, chronic cough has evolved from a mere symptom to a recognized disease. A key observation is that hypersensitivity of the afferent vagus and its central projections cause the state of cough hypersensitivity leading to the urge to cough being precipitated by otherwise innocuous stimuli. Clinical trial designs have also advanced, incorporating placebo run-in periods to reduce placebo effects and refining patient-reported outcomes to modern standards. Additionally, the realization that the variability in chronic cough, both diurnal and day-to-day, has highlighted the need for continuous cough monitoring, which has only recently been available consequence to the revolution in electronic applications. However, progress is hindered by a widespread lack of awareness among healthcare professionals and patients, underscoring the urgent need for education on this condition.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"709-720"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Value-based outcome measures in cough. 基于价值的咳嗽结果测量。

Expert review of respiratory medicine Pub Date : 2025-07-01 Epub Date: 2025-04-28 DOI: 10.1080/17476348.2025.2498419

Katherine L Rhatigan, Peter S P Cho

引用次数: 0

Lung ultrasound in children with asthma exacerbations: a systematic review and meta-analysis. 哮喘患儿肺部超声检查：系统回顾和荟萃分析。

Expert review of respiratory medicine Pub Date : 2025-07-01 Epub Date: 2025-04-21 DOI: 10.1080/17476348.2025.2495166

Lucypaula Andrade Pinheiro Fernandes, Jose Dirceu Ribeiro

{"title":"Lung ultrasound in children with asthma exacerbations: a systematic review and meta-analysis.","authors":"Lucypaula Andrade Pinheiro Fernandes, Jose Dirceu Ribeiro","doi":"10.1080/17476348.2025.2495166","DOIUrl":"10.1080/17476348.2025.2495166","url":null,"abstract":"Introduction: Lung ultrasound (LUS) is a noninvasive radiation-free imaging tool used to evaluate respiratory conditions, particularly in children and adolescents with asthma exacerbations. However, its role in diagnosing and managing asthma exacerbations remains unclear. We aimed to demonstrate LUS findings in pediatric asthma exacerbations, focusing on patterns such as B-lines, consolidation, and pleural abnormalities.Methods: A systematic review was conducted following the Preferred reporting items for systematic reviews and meta-analyses guidelines. Databases such as MEDLINE/PubMed and EMBASE were reviewed. The eligibility criterion was observational studies on LUS for pediatric asthma exacerbations. Bias risk was assessed using a validated tool. Data were analyzed both qualitatively and quantitatively, with findings summarized and meta-analysis conducted.Results: Five studies involving 192 participants were included in the analysis. The LUS findings included B-lines, consolidation, and pleural abnormalities. Meta-analysis revealed that 52.0% (95% confidence interval: 23.0-80.3) of the cases demonstrated positive LUS findings.Conclusions: LUS exhibited potential for diagnosing asthma exacerbations, particularly in identifying B-lines, consolidation, and pleural abnormalities. However, variability in detection rates was observed across different studies, which might be due to the differences in study populations and criteria. Despite these limitations, LUS can be a valuable tool for managing asthma exacerbations.Protocol registration: www.crd.york.ac.uk/Prospero identifier CRD42021244729.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"733-740"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An update on spinal cord injury and diaphragm neuromotor control. 脊髓损伤和膈神经运动控制的最新进展。

Expert review of respiratory medicine Pub Date : 2025-07-01 Epub Date: 2025-04-22 DOI: 10.1080/17476348.2025.2495165

Obaid U Khurram, Gary C Sieck

{"title":"An update on spinal cord injury and diaphragm neuromotor control.","authors":"Obaid U Khurram, Gary C Sieck","doi":"10.1080/17476348.2025.2495165","DOIUrl":"10.1080/17476348.2025.2495165","url":null,"abstract":"Introduction: Understanding neuromotor control of the diaphragm muscle (DIAm) is the foundation for developing therapeutic approaches for functional recovery of ventilatory and non-ventilatory behaviors. Although the DIAm is the primary inspiratory pump, it plays a vital role in a wide variety of higher-force behaviors including airway clearance activities. After spinal cord injury (SCI), higher-force behaviors experience the greatest deficits. A classification scheme for SCI that incorporates this information would be clinically valuable.Areas covered: We begin by presenting foundational information about DIAm motor units. In addition, we introduce a classification scheme of SCI based on the impact it has on neural circuitry involved in breathing and other functions of the DIAm. Finally, we consider various promising therapeutic options available to improve DIAm motor function. Relevant literature was identified by searching PubMed and Google Scholar without specific limits on the dates.Expert opinion: Classification of SCI based on its impact on the neural circuitry involved in DIAm motor behaviors is an important part of developing effective therapeutics. An approach that considers the specific type of SCI and leverages a combination of interventions will likely yield the best outcomes for restoring both ventilatory and non-ventilatory functions.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"679-695"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12213230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to the Editor: 'Roles of vitamins and nutrition in obstructive sleep apnea'. 致编辑的信：“维生素和营养在阻塞性睡眠呼吸暂停中的作用”。

Expert review of respiratory medicine Pub Date : 2025-07-01 Epub Date: 2025-04-26 DOI: 10.1080/17476348.2025.2499145

Dalmacito A Cordero

引用次数: 0

Idiopathic pleuroparenchymal fibroelastosis: diagnosis and management. 特发性胸膜实质纤维弹性病的诊断和治疗。

Expert review of respiratory medicine Pub Date : 2025-07-01 Epub Date: 2025-05-05 DOI: 10.1080/17476348.2025.2499651

Hiroshi Ishii, Yoshiaki Kinoshita, Naoki Hamada, Masaki Fujita, Hisako Kushima

{"title":"Idiopathic pleuroparenchymal fibroelastosis: diagnosis and management.","authors":"Hiroshi Ishii, Yoshiaki Kinoshita, Naoki Hamada, Masaki Fujita, Hisako Kushima","doi":"10.1080/17476348.2025.2499651","DOIUrl":"10.1080/17476348.2025.2499651","url":null,"abstract":"Introduction: Idiopathic pleuroparenchymal fibroelastosis (iPPFE) is a rare progressive interstitial lung disease characterized by upper-lobe fibrosis, severe restrictive impairment, and poor prognosis. Unlike idiopathic pulmonary fibrosis, in which acute exacerbations, chronic respiratory failure, and lung cancer are the major causes of death, iPPFE primarily leads to progressive respiratory failure, often complicated by malnutrition and recurrent pneumothorax. Despite growing recognition, its pathogenesis remains unclear and no effective treatments exist.Areas covered: This review summarizes the epidemiological, clinical, radiological, and pathological features of iPPFE, as well as diagnostic and prognostic advancements. Key prognostic factors include weight loss, reduced forced vital capacity, hypercapnia, and lower-lobe interstitial pneumonia. Serum biomarkers (e.g. latent transforming growth factor-beta binding protein-4) are being explored for early detection and prognostic purposes. Although antifibrotic agents show limited efficacy, supportive care - pulmonary rehabilitation, nutritional management, and pneumothorax prevention - remains essential. Research on the fibroelastotic pathways may inform the development of future therapies.Expert opinion: IPPFE remains a challenging disease. Therefore, early diagnosis and comprehensive management of this condition are crucial. Future research should refine prognostic models and explore novel therapeutic approaches for treating fibroelastosis. Lung transplantation may be an option for select patients. Further studies are required to optimize these outcomes.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"697-708"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interventional strategies to unload the right ventricle: a systematic review. 卸载右心室的介入策略：系统回顾。

Expert review of respiratory medicine Pub Date : 2025-07-01 Epub Date: 2025-05-15 DOI: 10.1080/17476348.2025.2495164

Leila Alajbegovic, Irene M Lang

{"title":"Interventional strategies to unload the right ventricle: a systematic review.","authors":"Leila Alajbegovic, Irene M Lang","doi":"10.1080/17476348.2025.2495164","DOIUrl":"10.1080/17476348.2025.2495164","url":null,"abstract":"Introduction: The function of the right ventricle (RV) is dependent on preload, end-systolic elastance (afterload), and intrinsic RV contractility. RV dysfunction comprises dilatation and hypertrophy, leading to RV failure and commonly death despite advances in medical treatments. This systematic review summarizes current and future interventional treatments to mechanically unload the RV. First, this review focuses on targeting pulmonary vascular afterload by addressing 1. Catheter-directed treatment for acute pulmonary embolism, 2. Balloon Pulmonary Angioplasty for chronic thromboembolic pulmonary hypertension, and 3. Pulmonary Artery Denervation for pulmonary hypertension. Second, mechanical support systems for enhancing RV contractility and interventions targeting tricuspid regurgitation as a cause of RV failure are discussed.Methods: On 2nd December 2024, a systematic search for publications between 2022 and 2025 was performed, using MEDLINE, EMBASE, Cochrane, and SCOPUS. The primary outcome was an improvement in hemodynamic measurements. Secondary outcomes included in-hospital mortality and complications. Meta-analyses, randomized controlled trials and for newer devices, observational studies and case series were included.Results: Of 32,852 screened studies, 80 were included. All treatments demonstrated various degrees of RV unloading.Conclusion: Novel treatments directed at mechanical RV unloading may improve survival, but further research is needed to examine long-term effects.Prospero registration: CRD42024616310.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"741-757"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An overview of management strategies for pediatric obstructive sleep apnea following adenotonsillectomy. 儿童腺扁桃体切除术后阻塞性睡眠呼吸暂停的治疗策略综述。

Expert review of respiratory medicine Pub Date : 2025-07-01 Epub Date: 2025-05-11 DOI: 10.1080/17476348.2025.2500630

Saudamini J Lele, Neila Louise Kline, Alyssa Claire Chapel, Felicity Lenes-Voit, Ron B Mitchell

{"title":"An overview of management strategies for pediatric obstructive sleep apnea following adenotonsillectomy.","authors":"Saudamini J Lele, Neila Louise Kline, Alyssa Claire Chapel, Felicity Lenes-Voit, Ron B Mitchell","doi":"10.1080/17476348.2025.2500630","DOIUrl":"10.1080/17476348.2025.2500630","url":null,"abstract":"Introduction: Persistent obstructive sleep apnea (OSA) following adenotonsillectomy is a frequently encountered challenge for clinicians including pediatricians, neurologists, otolaryngologists and sleep specialists, and if untreated poses severe health risks to children.Areas covered: This article evaluates the etiology and pathophysiology of persistent pediatric OSA. It also discusses the conditions that predispose some children to persistent OSA following adenotonsillectomy and reviews the different diagnostic modalities and various options for management of persistent pediatric OSA. A PubMed search was performed using the following terms in various combinations: persistent obstructive sleep apnea, pediatric obstructive sleep apnea, positive airway pressure, hypoglossal nerve stimulator, myofunctional therapy, nasal surgery, CPAP tolerance, obesity, Down syndrome, montelukast, frenulectomy, bariatric surgery, drug induced sleep endoscopy, cine MRI.Expert opinion: Persistent OSA following adenotonsillectomy is commonly seen in children. Understanding the anatomic and physiologic mechanisms at play is important to formulate specific management strategies. It is important to have a higher degree of suspicion for persistent OSA after an adenotonsillectomy in children with neurological comorbidities and obesity.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"721-731"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An update on oscillometry in asthma. 哮喘振荡测量的最新进展。

Expert review of respiratory medicine Pub Date : 2025-07-01 DOI: 10.1080/17476348.2025.2526774

Francesco Menzella, Rory Chan, Carlo Lombardi, Alvise Berti, Marcello Cottini

{"title":"An update on oscillometry in asthma.","authors":"Francesco Menzella, Rory Chan, Carlo Lombardi, Alvise Berti, Marcello Cottini","doi":"10.1080/17476348.2025.2526774","DOIUrl":"10.1080/17476348.2025.2526774","url":null,"abstract":"Introduction: Notwithstanding considerable progress in asthma management, a significant proportion of patients continue to demonstrate suboptimal control. Research has identified small airways dysfunction (SAD) as a critical site for airflow limitation and an independent risk factor of exacerbations, with airway oscillometry (AO) playing a pivotal role in this field.Areas covered: Spirometry is widely accepted as the gold standard for evaluating respiratory function. However, it is primarily sensitive to large airway obstruction… AO has emerged as a valuable tool for quantifying SAD, and recent studies have established strong correlations between AO, advanced imaging techniques and type 2 biomarkers. We conducted a review of the English-language literature from the beginning of the databases reviewed through June 2025.Expert opinion: In recent years, a substantial body of literature has emerged, leading to a resurgence of interest in the role of AO in asthma management. It is recommended that AO be utilized as a primary diagnostic tool for the early detection of SAD, even when spirometric values are within normal limits. The identification of patients with asthma in accordance with the criteria of defined severe SAD-oscillometry signifies the culmination of the evolution of AO from a research tool to a clinical tool.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"1-13"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144510055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0