Expert review of respiratory medicine最新文献

筛选
英文 中文
Scoping review of the literature supporting the exclusion of pulmonary embolism without radiation in children. 对支持排除儿童无放疗肺栓塞的文献进行范围综述。
IF 2.7
Expert review of respiratory medicine Pub Date : 2026-03-01 Epub Date: 2025-10-22 DOI: 10.1080/17476348.2025.2576336
Jeffrey A Kline, Angela M Ellison, Nathan Kuppermann
{"title":"Scoping review of the literature supporting the exclusion of pulmonary embolism without radiation in children.","authors":"Jeffrey A Kline, Angela M Ellison, Nathan Kuppermann","doi":"10.1080/17476348.2025.2576336","DOIUrl":"10.1080/17476348.2025.2576336","url":null,"abstract":"<p><strong>Introduction: </strong>Traditional dogma suggests that acute pulmonary embolism (PE) occurs rarely in children <18 years. However, in the emergency department (ED) setting, the frequency of PE diagnosis in children with signs or symptoms that raise suspicion for PE is unknown. This uncertainty is fueled by the lack of prospective studies of PE exclusion and diagnosis in children. Children occasionally die unexpectedly from an acute PE that was missed during the initial evaluation by a physician. However, over-testing also carries risks.</p><p><strong>Areas covered: </strong>This review addresses the risks of over-testing and radiation exposure, and the use of clinical criteria to assess the pretest probability of PE to decide when to test for this condition in children. We discuss what is known about the theoretical test threshold and the unstructured and structured pretest probability of PE assessment in children. Additionally, we review the theory behind the D-dimer assay and the current literature that has reported the diagnostic accuracy of the D-dimer for PE in children.</p><p><strong>Expert opinion: </strong>We propose a hypothetical clinical algorithm that incorporates the use of a prediction rule that relies upon both unstructured and structured pretest probability assessments, coupled with the D-dimer to safely rule out the diagnosis of PE in children without the use of radiation.</p>","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"279-286"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145294932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mycobacterium tuberculosis fluorescent and bioluminescent imaging technologies: addressing the issue of sensitivity. 结核分枝杆菌荧光和生物发光成像技术:解决敏感性问题。
IF 2.7
Expert review of respiratory medicine Pub Date : 2026-03-01 Epub Date: 2025-10-30 DOI: 10.1080/17476348.2025.2581338
Amanda C Zangirolami, Aaron B Benjamin, Hatice Ceylan Koydemir, Wenshe R Liu, Jeffrey D Cirillo
{"title":"<i>Mycobacterium tuberculosis</i> fluorescent and bioluminescent imaging technologies: addressing the issue of sensitivity.","authors":"Amanda C Zangirolami, Aaron B Benjamin, Hatice Ceylan Koydemir, Wenshe R Liu, Jeffrey D Cirillo","doi":"10.1080/17476348.2025.2581338","DOIUrl":"10.1080/17476348.2025.2581338","url":null,"abstract":"<p><strong>Introduction: </strong>Tuberculosis (TB), caused by <i>Mycobacterium tuberculosis</i> (Mtb), is a common cause of death in humans worldwide. The slow growth rate of Mtb (~20 hours) makes progress in research slow and diagnosis difficult.</p><p><strong>Areas covered: </strong>Imaging technologies that can quantify viability and infectious load can have a profound impact on progress toward new therapeutics and vaccines and allow rapid diagnosis. Although imaging can quantify bacterial loads throughout an entire animal in real-time, sensitivity is a key limitation. Fluorescent and bioluminescent recombinant strains have been used within the TB field and in other bacteria but have a threshold of ~10<sup>3</sup> bacteria in mice. Reporter enzyme fluorescence (REF) is a new and very sensitive Mtb imaging technology that uses BlaC, a highly specific surface-localized β-lactamase, in combination with fluorogenic or bioluminescent probes. As such, REF can reduce the threshold to 10-100 bacteria in vivo and detect 10 bacteria within 10 minutes in vitro.</p><p><strong>Expert opinion: </strong>Recombinant reporter systems for imaging bacteria should continue to improve and may reach similar thresholds, but at present, REF remains the most sensitive approach. Furthermore, new more sensitive probes can be readily developed, suggesting that REF will ultimately allow detection of single bacteria in an infected host.</p>","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"295-306"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12604640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145403228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimally invasive surgical approaches for pneumothorax: evolution and current perspectives. 气胸的微创手术入路:发展和目前的观点。
IF 2.7
Expert review of respiratory medicine Pub Date : 2026-02-01 Epub Date: 2025-09-11 DOI: 10.1080/17476348.2025.2559439
Teruaki Mizobuchi, Yuki Ito, Akimu Sobue, Yuki Tada, Kaoru Nagato, Takayoshi Yamamoto
{"title":"Minimally invasive surgical approaches for pneumothorax: evolution and current perspectives.","authors":"Teruaki Mizobuchi, Yuki Ito, Akimu Sobue, Yuki Tada, Kaoru Nagato, Takayoshi Yamamoto","doi":"10.1080/17476348.2025.2559439","DOIUrl":"10.1080/17476348.2025.2559439","url":null,"abstract":"<p><strong>Introduction: </strong>PubMed was used for a literature search (1990-2025) on the minimally invasive surgical approaches for pneumothorax, which have evolved markedly, with video-assisted thoracic surgery (VATS) emerging as a preferred procedure. Systematic reviews of randomized control trials indicate that VATS is less invasive than traditional thoracotomy. Furthermore, uniportal VATS provides less postoperative pain and better cosmetic outcomes than thoracotomy. Currently, uniportal VATS seems preferred as the minimally invasive surgical approach for pneumothorax. New devices such as small-diameter thoracoscopes and forceps, which are used in uniportal subxiphoid VATS and uniportal subcostal robot-assisted thoracic surgery, may contribute to reducing the postoperative incidence of intercostal neuralgia and enhancing satisfaction with the cosmetic results.</p><p><strong>Areas covered: </strong>The ideal surgical approaches for pneumothorax, referencing guidelines, and studies from various countries.</p><p><strong>Expert opinion: </strong>This review explores various aspects of minimally invasive surgical approaches for pneumothorax. Uniportal VATS for pneumothorax via the intercostal approach is commonly performed worldwide and ensures high surgical quality. This review discusses what should be performed within the thoracic cavity to reduce the postoperative recurrence rate of pneumothorax, problems associated with thoracic adhesions that may be disadvantageous for pneumothorax patients in the future, and the latest surgical approaches that may become mainstream.</p>","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"149-157"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Home-based pulmonary rehabilitation and health coaching in fibrotic interstitial lung disease: a perspective on current evidence and future directions. 纤维化间质性肺疾病的家庭肺康复和健康指导:当前证据和未来方向的观点
IF 2.7
Expert review of respiratory medicine Pub Date : 2026-02-01 Epub Date: 2025-07-25 DOI: 10.1080/17476348.2025.2539540
Teng Moua, Roberto Benzo
{"title":"Home-based pulmonary rehabilitation and health coaching in fibrotic interstitial lung disease: a perspective on current evidence and future directions.","authors":"Teng Moua, Roberto Benzo","doi":"10.1080/17476348.2025.2539540","DOIUrl":"10.1080/17476348.2025.2539540","url":null,"abstract":"<p><strong>Introduction: </strong>The fibrotic interstitial lung diseases (f-ILD) are often progressive and debilitating lung diseases with significant symptom burden and impaired quality of life. Pulmonary rehabilitation (PR) has demonstrated improvements in dyspnea, physical function, and respiratory-related quality of life (RR-QoL) in patients with -f-ILD but had limited uptake and completion in real-world settings.</p><p><strong>Areas covered: </strong>A literature review was completed on the impact and limitations of traditional PR in f-ILD, with additional perspective on the use of home-based approaches and implementation of health coaching. Barriers to traditional center-based PR programs include patient and systems-based factors such as unawareness of benefit, emotional or psychological distress, and limited access. Home-based PR may address these limitations by removing travel barriers, increasing access with remote supervision and monitoring, and promoting social support by connecting care with familiar settings. Studies involving home-based PR in ILD have shown promise with improving functional and quality of life outcomes and high compliance rates. Health coaching is a collaborative paradigm for fostering behavior change and has demonstrated positive impact in the management of chronic diseases.</p><p><strong>Expert opinion: </strong>A combination of health coaching with home-based PR may address ongoing challenges of PR uptake and compliance as well as expand PR as a holistic and comprehensive intervention.</p>","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"121-131"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of strength training in patients with COPD: a systematic review. 力量训练对慢性阻塞性肺病患者的影响:一项系统综述。
IF 2.7
Expert review of respiratory medicine Pub Date : 2026-02-01 Epub Date: 2025-09-23 DOI: 10.1080/17476348.2025.2562638
María Barreiro Blanco, Clara Rodríguez-Gude, Iria Da Cuña-Carrera, Eva Lantarón-Caeiro
{"title":"Effects of strength training in patients with COPD: a systematic review.","authors":"María Barreiro Blanco, Clara Rodríguez-Gude, Iria Da Cuña-Carrera, Eva Lantarón-Caeiro","doi":"10.1080/17476348.2025.2562638","DOIUrl":"10.1080/17476348.2025.2562638","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic obstructive pulmonary disease (COPD) is a heterogeneous lung condition characterized by chronic respiratory symptoms causing persistent, often progressive airflow obstruction. Strength training is a therapeutic option to prevent and/or reverse muscle dysfunction in COPD patients. Objective: to analyze the literature on the effects of strength training in COPD patients.</p><p><strong>Methods: </strong>A systematic review from the last ten years was conducted in August 2024 across PubMed, Scopus, WOS, Medline and CINAHL databases. The search included studies examining resistance training for upper and lower limbs. Methodological quality was analyzed using the PEDro scale and the RoB2 was used for risk of bias.</p><p><strong>Results: </strong>Six randomized controlled trials were eligible for inclusion, obtaining an excellent or good methodological quality. Most repeated variables were exercise capacity, quality of life and muscle strength, finding statistically significant positive results in all of them.</p><p><strong>Conclusions: </strong>Strength training appears to be safe and effective for COPD treatment, with improvements in exercise capacity, activities of daily living, muscle strength, lung function, quality of life and inflammatory levels. However, scientific evidence on this topic is scarce, and future high-quality, long-term studies are necessary to establish standardized protocols and assess the sustained benefits of strength training in COPD patients.<b>Protocol registration:</b> Identifier is CRD42024572717.</p>","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"189-197"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contemporary issues in pediatric prehospital airway management. 儿科院前气道管理的当代问题。
IF 2.7
Expert review of respiratory medicine Pub Date : 2026-02-01 Epub Date: 2025-09-22 DOI: 10.1080/17476348.2025.2562632
Henry E Wang, Matthew Hansen, Manish I Shah, Nichole Bosson, John M VanBuren, Barbara Wendelberger, Jennifer Frey, Alexander Keister, Roger J Lewis, Marianne Gausche-Hill
{"title":"Contemporary issues in pediatric prehospital airway management.","authors":"Henry E Wang, Matthew Hansen, Manish I Shah, Nichole Bosson, John M VanBuren, Barbara Wendelberger, Jennifer Frey, Alexander Keister, Roger J Lewis, Marianne Gausche-Hill","doi":"10.1080/17476348.2025.2562632","DOIUrl":"10.1080/17476348.2025.2562632","url":null,"abstract":"<p><strong>Introduction: </strong>Airway management is one of the most important interventions performed by paramedics in the prehospital setting. While the standard of care for over 40 years, multiple studies highlight pitfalls associated with prehospital airway management in adults. Considerably less research describes prehospital airway management in children.</p><p><strong>Areas covered: </strong>We searched PubMed for articles from 2000 to present using the keywords 'children,' 'airway management,' 'intubation intratracheal,' 'Emergency Medical Services,' and 'paramedic.' Studies highlight the pitfalls of adult prehospital endotracheal intubation such as tube misplacement and dislodgement, multiple and failed insertion attempts, interruptions in chest compressions, and inadvertent hyperventilation. Multicenter clinical trials including the PART and Airways-2 trials support the use of newer supraglottic airways as potential alternatives to intubation in adults. Only limited data describe prehospital airway management in children, including only one clinical trial performed 25 years ago.</p><p><strong>Expert opinion: </strong>New studies are needed to guide paramedic pediatric airway management practices. The Pediatric Prehospital Airway Resuscitation Trial (Pedi-PART) is an ongoing multicenter clinical trial that will provide critical new knowledge to guide prehospital pediatric airway management practices.</p>","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"113-120"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breastfeeding, lung development and asthma. 母乳喂养、肺部发育和哮喘。
IF 2.7
Expert review of respiratory medicine Pub Date : 2026-02-01 Epub Date: 2025-08-11 DOI: 10.1080/17476348.2025.2546611
Sergio Verd
{"title":"Breastfeeding, lung development and asthma.","authors":"Sergio Verd","doi":"10.1080/17476348.2025.2546611","DOIUrl":"10.1080/17476348.2025.2546611","url":null,"abstract":"","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"105-108"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pleuroparenchymal fibroelastosis: review of 81 cases. 胸膜实质纤维弹性增生81例分析。
IF 2.7
Expert review of respiratory medicine Pub Date : 2026-02-01 Epub Date: 2025-09-09 DOI: 10.1080/17476348.2025.2555079
Misbah Baqir, Allison M LeMahieu, Thomas E Hartman, Wigdan H Farah, Eunhee E Yi, Jay H Ryu
{"title":"Pleuroparenchymal fibroelastosis: review of 81 cases.","authors":"Misbah Baqir, Allison M LeMahieu, Thomas E Hartman, Wigdan H Farah, Eunhee E Yi, Jay H Ryu","doi":"10.1080/17476348.2025.2555079","DOIUrl":"10.1080/17476348.2025.2555079","url":null,"abstract":"<p><strong>Background: </strong>Pleuroparenchymal fibroelastosis (PPFE) is an upper lobe - predominant interstitial pneumonia pattern that can be idiopathic or secondary and has unclear clinical characteristics, disease course, and prognostic factors. This study analyzed PPFE patient characteristics, identified mortality predictors, and compared disease progression between idiopathic and secondary PPFE.</p><p><strong>Research design and methods: </strong>We retrospectively identified patients with PPFE and analyzed demographic, clinical, radiologic, and pathologic data. Linear regression mixed models were used to assess predictors of mortality and lung function decline.</p><p><strong>Results: </strong>Among 81 patients identified, 73% were women, median age was 69.4 years, and 75% were nonsmokers. Idiopathic PPFE comprised 46% of cases; secondary PPFE was most commonly familial (40%) or autoimmune related (33%). Over a median follow-up of 777 days, 38% died; the 5-year survival rate was 53%. Mortality risk did not differ between idiopathic and secondary PPFE. Lower body mass index, lower forced vital capacity (FVC) at diagnosis, and smoking history predicted mortality. The decline in FVC was slower in idiopathic PPFE than secondary PPFE.</p><p><strong>Conclusions: </strong>Idiopathic and secondary PPFE differ in FVC decline but not in mortality risk. Familial and autoimmune conditions are the most common secondary causes.</p>","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"217-226"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144983870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of artificial intelligence for the detection of obstructive sleep apnea based on clinical and demographic data: a systematic review. 基于临床和人口统计数据的人工智能在阻塞性睡眠呼吸暂停检测中的应用:系统综述。
IF 2.7
Expert review of respiratory medicine Pub Date : 2026-02-01 Epub Date: 2025-10-05 DOI: 10.1080/17476348.2025.2567046
Manuel Casal-Guisande, Mar Mosteiro-Añón, María Torres-Durán, Alberto Comesaña-Campos, Alberto Fernández-Villar
{"title":"Application of artificial intelligence for the detection of obstructive sleep apnea based on clinical and demographic data: a systematic review.","authors":"Manuel Casal-Guisande, Mar Mosteiro-Añón, María Torres-Durán, Alberto Comesaña-Campos, Alberto Fernández-Villar","doi":"10.1080/17476348.2025.2567046","DOIUrl":"10.1080/17476348.2025.2567046","url":null,"abstract":"<p><strong>Introduction: </strong>Artificial intelligence (AI) has shown promise in enhancing the detection and stratification of obstructive sleep apnea (OSA) using clinical and demographic data. This systematic review assessed the effectiveness of AI models, methodological quality, and future research needs.</p><p><strong>Methods: </strong>Following PRISMA guidelines, a systematic search of PubMed (2014-2024) identified studies applying AI to detect or stratify OSA using clinical/demographic data, validated against polysomnography or cardiorespiratory polygraphy, and reporting performance metrics such as the area under the curve (AUC). Studies primarily based on wearable devices were excluded. Methodological quality and risk of bias were evaluated using the PROBAST tool.</p><p><strong>Results: </strong>Of 447 records, 26 met inclusion criteria. Common algorithms included decision trees, support vector machines, and neural networks, frequently using variables such as age, BMI, neck circumference, and comorbidities. AUC values ranged from 0.62 to 0.93, with most exceeding 0.80. Research output increased substantially between 2021 and 2024. Methodological heterogeneity and limited external validation hindered comparability. Exclusion of incomplete cases was a recurrent issue.</p><p><strong>Conclusions: </strong>AI models show potential for improving OSA detection, but methodological limitations restrict generalizability. Future studies should prioritize external validation, diverse populations, and adherence to standardized reporting frameworks to enable clinical translation.</p><p><strong>Protocol registration: </strong>https://www.crd.york.ac.uk/PROSPERO/view/CRD420251025868 identifier is CRD420251025868.</p>","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"199-216"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An update on clinical recommendations for cardiopulmonary exercise testing in children with respiratory diseases. 呼吸系统疾病患儿心肺运动试验临床建议的最新进展
IF 2.7
Expert review of respiratory medicine Pub Date : 2026-02-01 Epub Date: 2025-08-14 DOI: 10.1080/17476348.2025.2547418
Tim Takken, Tamara Ruuls, Mattiènne Van der Kamp, Bernardus Thio, Marco van Brussel, Erik H J Hulzebos
{"title":"An update on clinical recommendations for cardiopulmonary exercise testing in children with respiratory diseases.","authors":"Tim Takken, Tamara Ruuls, Mattiènne Van der Kamp, Bernardus Thio, Marco van Brussel, Erik H J Hulzebos","doi":"10.1080/17476348.2025.2547418","DOIUrl":"10.1080/17476348.2025.2547418","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiopulmonary exercise testing (CPET) is a diagnostic-integrated tool for evaluating cardiovascular, ventilatory, and metabolic functional limitations in children with respiratory diseases. Recently, novel applications have emerged, revealing dynamic abnormalities that may go unnoticed in standard static cardiac and pulmonary function tests. Given its clinical importance and novel research findings, updated recommendations are warranted.</p><p><strong>Areas covered: </strong>We conducted a narrative review based on a literature search up to April 2025. This review provides an update on the application of CPET in pediatric respiratory diseases, covering physiological differences to adults, non-traditional CPET metrics such as the oxygen uptake efficiency slope (OUES), tidal volume to inspiratory time ratio (VT/Ti), and recent reference values. Indications, contraindications, and standardized protocols are discussed, alongside emerging trends in CPET technology.</p><p><strong>Expert opinion: </strong>CPET is a potent tool for assessing, evaluating, and diagnosing pediatric respiratory diseases. Standardized protocols, age-specific reference values, and novel CPET parameters enhance clinical utility. Future research should refine interpretation, integrate artificial intelligence for data analysis, and facilitate CPET for younger children.</p>","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"133-147"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144839426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书