Expert review of respiratory medicine最新文献

An update on endobronchial valve therapy for severe emphysema: real world data and special indications. 严重肺气肿的支气管内瓣膜治疗最新进展：真实世界的数据和特殊适应症。

Expert review of respiratory medicine Pub Date : 2024-11-19 DOI: 10.1080/17476348.2024.2431522

Tadashi Sakaguchi, Jorine E Hartman, Dirk-Jan Slebos

{"title":"An update on endobronchial valve therapy for severe emphysema: real world data and special indications.","authors":"Tadashi Sakaguchi, Jorine E Hartman, Dirk-Jan Slebos","doi":"10.1080/17476348.2024.2431522","DOIUrl":"10.1080/17476348.2024.2431522","url":null,"abstract":"Introduction: Bronchoscopic lung volume reduction (BLVR) using one-way endobronchial valves (EBV) is a guideline therapy for patients with severe emphysema without interlobar collateral ventilation, based on solid results from multiple randomized clinical trials (RCTs). However, whether its efficacy and safety in real-world clinical settings are comparable to those observed in RCTs has not been fully investigated. Additionally, recent reports on EBV therapy have focused on specialized populations (e.g. very low FEV1, very low DLCO) that were not represented in the RCTs.Areas covered: We have summarized the efficacy and safety of the publications on BLVR with EBVs in real-world settings and in specialized populations, and have discussed these findings in relation to the RCTs data.Expert opinion: The benefits of BLVR with EBVs have effectively translated into real-world clinical practice with a tolerable safety profile. These benefits and acceptable safety profile were also observed in specialized populations not fully represented in RCTs. We believe it is crucial to establish a nationwide registry in each country to keep track of outcome for quality and consistency, and to have a multidisciplinary COPD team discussion in each treating institution to keep on ensuring the successful clinical practice of BLVR with EBVs.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is the nicotine metabolite ratio a useful tool to improve the effectiveness, safety, and adherence to quitting smoking? Systematic review of the literature and meta-analysis. 尼古丁代谢物比率是提高戒烟有效性、安全性和依从性的有用工具吗？文献的系统回顾和荟萃分析。

Expert review of respiratory medicine Pub Date : 2024-11-19 DOI: 10.1080/17476348.2024.2429675

José Ignacio de Granda-Orive, Adolfo Alonso-Arroyo, Daniel López-Padilla, Rafael Aleixandre-Benavent, Segismundo Solano-Reina, Juan Antonio Riesco-Miranda, Carlos Rábade-Castedo, Miguel Jiménez-Gómez, Fernando Revuelta-Salgado, Carlos A Jiménez-Ruiz

{"title":"Is the nicotine metabolite ratio a useful tool to improve the effectiveness, safety, and adherence to quitting smoking? Systematic review of the literature and meta-analysis.","authors":"José Ignacio de Granda-Orive, Adolfo Alonso-Arroyo, Daniel López-Padilla, Rafael Aleixandre-Benavent, Segismundo Solano-Reina, Juan Antonio Riesco-Miranda, Carlos Rábade-Castedo, Miguel Jiménez-Gómez, Fernando Revuelta-Salgado, Carlos A Jiménez-Ruiz","doi":"10.1080/17476348.2024.2429675","DOIUrl":"10.1080/17476348.2024.2429675","url":null,"abstract":"Introduction: We have carried out a systematic review of the literature (SRL) and a meta-analysis (MA) to answer: 1. Validity of the nicotine metabolite ratio (NMR) in improving the effectiveness of pharmacological treatments (PT) for smoking cessation (SC). 2. Validity of the NMR to improve the safety of the use of these PT? and 3. Validity of NMR in improving adherence to these PT?Method: We carried out an SRL (six databases) and an MA for responding to the questions.Results: PT for SC (any treatment) is more effective in smoking subjects with slow NMR compared with fast NMR. Varenicline (VR) is equally effective in fast and slow NMR (RR 1.04 [CI 95% 0.75, 1.44]). When we compared those smokers who were treated to quit smoking with VR or nicotine replacement therapy (NRT) in fast metabolizers, we found that abstinence was in favor of those who were treated with VR (RR 1.40 [CI 95% 1.02, 1.91]). Those who were treated to quit smoking with NRT presented better results in slow Metabolizers (RR 0.70 [CI 95% 0.58, 0.83]). NMR increases the safety and adherence of treatments.Conclusions: We suggest that NMR is a good biomarker in the personalization of smoking cessation.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"1-27"},"PeriodicalIF":0.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142650434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What is new in synthetic lung surfactant protein technology? 合成肺表面活性蛋白技术有何新进展？

Expert review of respiratory medicine Pub Date : 2024-11-17 DOI: 10.1080/17476348.2024.2429669

Frans J Walther, Joseph A Zasadzinski, Alan J Waring

引用次数: 0

Some challenges in implementing updated European respiratory society (ERS)/American thoracic society (ATS)-2022 interpretive strategies for routine pulmonary function tests. 实施欧洲呼吸学会 (ERS)/ 美国胸腔学会 (ATS)-2022 更新的常规肺功能测试解释策略的一些挑战。

Expert review of respiratory medicine Pub Date : 2024-11-14 DOI: 10.1080/17476348.2024.2428217

Mariem Abdesslem, Balsam Barkous, Helmi Ben Saad

引用次数: 0

Advancements and challenges in the management of pneumonia in elderly patients with COPD. 慢性阻塞性肺病老年患者肺炎管理的进展与挑战。

Expert review of respiratory medicine Pub Date : 2024-11-06 DOI: 10.1080/17476348.2024.2422961

Sebastian Ocrospoma, Antonio Anzueto, Marcos I Restrepo

引用次数: 0

Recent advances in the use of liquid biopsy for the diagnosis and treatment of lung cancer. 利用液体活检诊断和治疗肺癌的最新进展。

Expert review of respiratory medicine Pub Date : 2024-11-03 DOI: 10.1080/17476348.2024.2423824

Valerio Gristina, Gianluca Russo, Tancredi Didier Bazan Russo, Giulia Busuito, Giuliana Iannì, Pasquale Pisapia, Claudia Scimone, Lucia Palumbo, Lorena Incorvaia, Giuseppe Badalamenti, Antonio Galvano, Viviana Bazan, Antonio Russo, Giancarlo Troncone, Umberto Malapelle, Francesco Pepe

{"title":"Recent advances in the use of liquid biopsy for the diagnosis and treatment of lung cancer.","authors":"Valerio Gristina, Gianluca Russo, Tancredi Didier Bazan Russo, Giulia Busuito, Giuliana Iannì, Pasquale Pisapia, Claudia Scimone, Lucia Palumbo, Lorena Incorvaia, Giuseppe Badalamenti, Antonio Galvano, Viviana Bazan, Antonio Russo, Giancarlo Troncone, Umberto Malapelle, Francesco Pepe","doi":"10.1080/17476348.2024.2423824","DOIUrl":"https://doi.org/10.1080/17476348.2024.2423824","url":null,"abstract":"Introduction: In the era of precision medicine, liquid biopsy rapidly emerges as an integrative diagnostic tool to successfully stratify solid tumor patients in accordance with molecular fingerprinting. As the matter of fact, a plethora of analytes may be isolated from liquid biosources supporting the potential application of liquid biopsy in several clinical scenarios. Despite this promising role, liquid biopsy is drastically affected by low abundance of analytes in biological matrix requiring highly sensitive technologies, trained personnel, and optimized diagnostic procedures to successfully administrate this revolutionary diagnostic tool in clinical practice.Areas covered: This review aims to investigate the recent advancements in technical approaches available to manage liquid biopsy samples, particularly focusing on their application in LC diagnosis and treatment.Expert opinion: The rapidly evolving scenario of liquid biopsy-based approaches is revolutionizing clinical administration of lung cancer patients. Of note, the integration of genomic, epigenomic, and transcriptomic markers lays the basis for 'comprehensive' molecular fingerprinting of lung cancer patients. Here, the next-generation technologies are fundamental in molecular profiling in diagnostic routine biofluids.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What is the future of inhaled antibiotics for bronchiectasis? 吸入式抗生素治疗支气管扩张症的前景如何？

Expert review of respiratory medicine Pub Date : 2024-11-03 DOI: 10.1080/17476348.2024.2423825

Emma D Johnson, James D Chalmers

引用次数: 0

Pulmonary endoscopy - central to an interventional pulmonology program. 肺内窥镜检查--介入肺病学项目的核心。

Expert review of respiratory medicine Pub Date : 2024-11-01 Epub Date: 2024-10-28 DOI: 10.1080/17476348.2024.2413561

Sally Griffiths, Lucy Power, David Breen

{"title":"Pulmonary endoscopy - central to an interventional pulmonology program.","authors":"Sally Griffiths, Lucy Power, David Breen","doi":"10.1080/17476348.2024.2413561","DOIUrl":"10.1080/17476348.2024.2413561","url":null,"abstract":"Introduction: Pulmonary endoscopy occupies a central role in Interventional Pulmonology and is frequently the mainstay of diagnosis of respiratory disease, in particular lung malignancy. Older techniques such as rigid bronchoscopy maintain an important role in central airway obstruction. Renewed interest in the peripheral pulmonary nodule is driving major advances in technologies to increase the diagnostic accuracy and advance new potential endoscopic therapeutic options.Areas covered: This paper describes the role of pulmonary endoscopy, in particular ultrasound in the diagnosis and staging of lung malignancy. We will explore the recent expansion of ultrasound to include endoscopic ultrasound - bronchoscopy (EUS-B) and combined ultrasound (CUS) techniques. We will discuss in detail the advances in the workup of the peripheral pulmonary nodule.We performed a non-systematic, narrative review of the literature to summarize the evidence regarding the indications, diagnostic yield, and safety of current bronchoscopic sampling techniques.Expert opinion: EBUS/EUS-B has revolutionized the diagnosis and staging of thoracic malignancy resulting in more accurate assessment of the mediastinum compared to mediastinoscopy alone, thus reducing the rate of futile thoracotomies. Although major advances in the assessment of the peripheral pulmonary nodule have been made, the role of endoscopy in this area requires further clarification and investigation.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"843-860"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142383058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulmonary rehabilitation guidelines for COPD; where do we go from here? 慢性阻塞性肺疾病肺康复指南；我们该何去何从？

Expert review of respiratory medicine Pub Date : 2024-11-01 Epub Date: 2024-10-18 DOI: 10.1080/17476348.2024.2418512

Michele Vitacca, Mara Paneroni

引用次数: 0

Pulmonary tuberculosis in non-HIV adults: an evergreen old-fashioned disease in high-income countries. A narrative review. 非艾滋病毒成人肺结核：高收入国家的常青老病。叙述性综述。

Expert review of respiratory medicine Pub Date : 2024-11-01 Epub Date: 2024-10-28 DOI: 10.1080/17476348.2024.2418932

Marco Guerrieri, Elena Bargagli, Lucia Cassai, Sara Gangi, Michele Genovese, Magda Viani, Andrea S Melani

{"title":"Pulmonary tuberculosis in non-HIV adults: an evergreen old-fashioned disease in high-income countries. A narrative review.","authors":"Marco Guerrieri, Elena Bargagli, Lucia Cassai, Sara Gangi, Michele Genovese, Magda Viani, Andrea S Melani","doi":"10.1080/17476348.2024.2418932","DOIUrl":"10.1080/17476348.2024.2418932","url":null,"abstract":"Introduction: Tuberculosis (TB), an infective air-borne disease with worldwide non-homogeneous distribution, remains a top cause of morbidity and mortality. TB control is linked to early diagnosis and proper treatment of contagious TB cases and infected subjects at high risk of developing TB.Areas covered: A narrative review of pulmonary TB in non-HIV adults with reference to high-income countries. Modern medicine offers several advancements in diagnostics and therapeutics of TB, but they often remain to be extensively implemented in real life. In high-income countries TB is now relatively uncommon, but it remains a health and socio-economic burden that should not be underestimated.Expert opinion: Pulmonologists should maintain expertise toward TB for several reasons. First, the lung is the most common and the infectious moiety of TB. Second, TB remains a global issue due to common travels of western people and migrations from areas with high incidence of TB. Third, as TB has heterogenous clinics, its prompt diagnosis may be difficult. Fourth, TB is a curable disease, but its management is complex and predisposes to poor adherence with failures/relapses and selection of drug-resistant strains.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"861-872"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0