Expert review of respiratory medicine最新文献

Racial/ethnic disparities in environmental respiratory allergies among cancer patients: national health interview survey analysis. 癌症患者环境呼吸过敏的种族差异：全国健康访谈调查分析。

IF 2.7

Expert review of respiratory medicine Pub Date : 2026-05-06 DOI: 10.1080/17476348.2026.2670015

Lohuwa Mamudu, Yazmin Acosta, Erasmus Tetteh-Bator, Danny H Kim, Phillip Gedalanga, Bo Young Park, Mubarak Osman, Sampson E Akwafuo, Mohammad Masum, Paul H Atandoh

{"title":"Racial/ethnic disparities in environmental respiratory allergies among cancer patients: national health interview survey analysis.","authors":"Lohuwa Mamudu, Yazmin Acosta, Erasmus Tetteh-Bator, Danny H Kim, Phillip Gedalanga, Bo Young Park, Mubarak Osman, Sampson E Akwafuo, Mohammad Masum, Paul H Atandoh","doi":"10.1080/17476348.2026.2670015","DOIUrl":"10.1080/17476348.2026.2670015","url":null,"abstract":"Background: Environmental respiratory allergies (ERA) can worsen the quality of life of cancer patients. This study examined the prevalence, association, and racial/ethnic disparities in ERA diagnosis among cancer patients in the United States.Methods: We analyzed a retrospective cross-sectional dataset from the National Health Interview Survey (2021) involving weighted samples of 1,879 U.S. adults aged ≥18 years. Bivariate and multivariable analyses were conducted, adjusting for covariates.Results: The prevalence rate of ERA among cancer patients was 55.5%, with a significant difference among race/ethnicity. Non-Hispanic other/Multiracial had the highest prevalence of ERA (83.1%), followed by non-Hispanic Asians (68.2%), and non-Hispanic Black/African American (65.2%). Non-Hispanic Other/Multiracial cancer patients had significantly higher odds of ERA compared to non-Hispanic Whites in sociodemographic, socioeconomic, and fully adjusted models, respectively. Similarly, Non-Hispanic Blacks/African Americans had increased odds of ERA compared to non-Hispanic Whites (AOR = 1.58, 95% CI = 1.00-2.56) after adjusting for education and health insurance. Additionally, race/ethnic minority cancer patients were 1.22 times more likely to be at risk of ERA than their non-Hispanic White counterparts.Conclusion: This study demonstrates that racial/ethnic disparities exist in ERA diagnosis among cancer patients. Therefore, targeted interventions aimed at addressing these disparities can help improve the quality of life for cancer patients.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"1-9"},"PeriodicalIF":2.7,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147825049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COPD and rheumatoid arthritis: shared inflammatory pathways and clinical implications. 慢性阻塞性肺病和类风湿关节炎：共同的炎症途径和临床意义

IF 2.7

Expert review of respiratory medicine Pub Date : 2026-05-01 Epub Date: 2025-11-17 DOI: 10.1080/17476348.2025.2590785

Mohamed Abdulkadir, Catherine Greene

{"title":"COPD and rheumatoid arthritis: shared inflammatory pathways and clinical implications.","authors":"Mohamed Abdulkadir, Catherine Greene","doi":"10.1080/17476348.2025.2590785","DOIUrl":"10.1080/17476348.2025.2590785","url":null,"abstract":"Introduction: Rheumatoid Arthritis (RA) and Chronic Obstructive Pulmonary Disease (COPD) are chronic, progressive inflammatory conditions that may coexist, contributing to greater morbidity and complexity in clinical management. The overlap between these two conditions remains under-recognized despite growing evidence of shared pathogenic mechanisms and risk factors.Areas covered: This review explores the emerging evidence linking RA and COPD, focusing on shared inflammatory pathways, genetic susceptibility, and environmental influences such as smoking and air pollution. A comprehensive literature search was conducted using PubMed and Scopus databases with keywords including 'rheumatoid arthritis,' 'COPD,' 'pulmonary involvement,' and 'inflammatory overlap.' Key findings highlight diagnostic challenges stemming from symptom overlap, the underdiagnosis of COPD in RA patients, and the clinical impact of dual disease burden. The review also discusses the importance of multidisciplinary collaboration, optimal use of spirometry, imaging, and symptom-based questionnaires as screening tools, and strategies for balancing immunosuppressive therapy with respiratory health.Expert opinion: Greater awareness of COPD as a pulmonary manifestation of RA is essential. Early recognition through systematic screening and integrated care models may significantly improve patient outcomes and reduce disease burden.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"513-522"},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145524863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The promise of blue light in combating ventilator-associated pneumonia. 蓝光治疗呼吸机相关性肺炎的前景。

IF 2.7

Expert review of respiratory medicine Pub Date : 2026-05-01 Epub Date: 2025-11-10 DOI: 10.1080/17476348.2025.2587311

Aashay Mardikar, Sudarshan Ramanan, Mathew Stephen, Robert J Graham, Aditya Gunturi

{"title":"The promise of blue light in combating ventilator-associated pneumonia.","authors":"Aashay Mardikar, Sudarshan Ramanan, Mathew Stephen, Robert J Graham, Aditya Gunturi","doi":"10.1080/17476348.2025.2587311","DOIUrl":"10.1080/17476348.2025.2587311","url":null,"abstract":"Introduction: Ventilator-associated pneumonia (VAP) is a deadly hospital-acquired infection that can impact between 5% and 40% of patients receiving mechanical ventilation. While preventative measures such as prophylactic antibiotics and oral care provided by the nursing staff exist, they are often insufficient and carry their own set of challenges. As a result, VAP not only increases hospital length of stay and rates of mortality but can also put a significant financial burden on hospitals and care centers.Areas covered: This article provides an overview of current measures and ideas in development for VAP prevention, as well as their challenges and downfalls. The use of light therapies in combating infection are also discussed, with a particular emphasis on antimicrobial blue light as a potential tool for dealing with VAP. A comprehensive literature search and narrative review was conducted using the PubMed database through June 2025.Expert opinion: Novel applications of blue light in VAP prevention may significantly improve patient outcomes. This technology may also help reduce rates of clinician burnout. This reduction is especially important in low- and middle-income countries where access to advanced resources may be limited. Thus, the authors urge development in this field as the need for infection-prevention technologies grows yearly.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"501-511"},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145461087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between polymorphisms in the TGF-β receptor gene and susceptibility towards chronic obstructive pulmonary disease in Northern Indians. 北部印第安人TGF-β受体基因多态性与慢性阻塞性肺疾病易感性的关系

IF 2.7

Expert review of respiratory medicine Pub Date : 2026-05-01 Epub Date: 2025-11-09 DOI: 10.1080/17476348.2025.2586151

Nidhi Mahajan, Vishal Chopra, Kranti Garg, Siddharth Sharma

{"title":"Relationship between polymorphisms in the TGF-β receptor gene and susceptibility towards chronic obstructive pulmonary disease in Northern Indians.","authors":"Nidhi Mahajan, Vishal Chopra, Kranti Garg, Siddharth Sharma","doi":"10.1080/17476348.2025.2586151","DOIUrl":"10.1080/17476348.2025.2586151","url":null,"abstract":"Background: Chronic Obstructive Pulmonary Disease (COPD) is a multifactorial respiratory disorder influenced by genetic, environmental, and lifestyle factors such as smoking. The Transforming Growth Factor Beta Receptor 1 (TGFBR1) plays a crucial role in regulating cell proliferation, differentiation, apoptosis, and immune modulation. Dysregulation of TGFBR1 may disrupt downstream signalling, leading to chronic inflammation, extracellular matrix accumulation in COPD. The present study aimed to evaluate the association of TGFBR1 gene variants rs7040869 (G>A), rs6478974 (A>T), rs4743325 (G>T), and rs597457 (C>A) with COPD susceptibility in a North Indian population.Methods: This study comprises 500 COPD cases and 500 controls. Genotyping of the selected single-nucleotide polymorphisms (SNPs) was performed, and statistical analyses, including logistic regression, haplotype analysis, Classification and Regression Tree (CART), and Multifactor Dimensionality Reduction (MDR), were applied to assess gene-disease associations.Results: The rs6478974 variant showed significant protective association with COPD, persisting after Bonferroni correction. Combined genotype analysis indicated that GA+GT genotypes of rs7040869 and rs4743325 increased disease risk, while CART identified rs6478974 and rs597457 as key interaction nodes.Conclusion: This study is the first in a North Indian cohort to identify the protective role of rs6478974 in COPD, emphasising the significance of TGFBR1 polymorphisms in disease pathogenesis and risk prediction.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"579-589"},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145484437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of the right ventricle in pulmonary arterial hypertension and imaging methods for non-invasive evaluation. 右心室在肺动脉高压中的作用及无创评价的影像学方法。

IF 2.7

Expert review of respiratory medicine Pub Date : 2026-05-01 Epub Date: 2026-01-01 DOI: 10.1080/17476348.2025.2601388

Tatiana Kiyota, Paulo Mendes, Monica Corso Pereira

{"title":"The role of the right ventricle in pulmonary arterial hypertension and imaging methods for non-invasive evaluation.","authors":"Tatiana Kiyota, Paulo Mendes, Monica Corso Pereira","doi":"10.1080/17476348.2025.2601388","DOIUrl":"10.1080/17476348.2025.2601388","url":null,"abstract":"Introduction: Pulmonary arterial hypertension (PAH) is a progressive disease characterized by the remodeling of pulmonary circulation, leading to increased pulmonary vascular resistance (PVR) and right ventricular (RV) overload. While the right heart may initially compensate, many patients ultimately face right heart failure and higher risk of mortality. Significant progress has been made in RV management, including advancements in molecular understanding, development of monitoring tools, and the exploration of new therapeutic pathways.Areas covered: A comprehensive literature search (January 2000-present) was conducted using PubMed and Embase. Search strategies focused on Pulmonary Arterial Hypertension and the Right Ventricle, incorporating specific concepts such as RV-pulmonary arterial (RV-PA) coupling and noninvasive assessment methods, including Echocardiography (2D and 3D) and Cardiac Magnetic Resonance (CMR).Expert opinion: The use of appropriate parameters to identify cardiac function deterioration is crucial for monitoring PAH patients. In this regard, imaging tests and new parameters have increasingly demonstrated added value when combined with traditional tools. This review highlights the central role of the RV in PAH pathophysiology and progression. We present and discuss noninvasive imaging methods for RV assessment, focusing on summarizing recent studies that support the use of noninvasive measures to evaluate RV-PA coupling and right systolic function.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"543-567"},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145716964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding the relationship between eosinophils and chronic obstructive pulmonary disease. A new dawn? 了解嗜酸性粒细胞与慢性阻塞性肺疾病的关系。一个新的黎明？

IF 2.7

Expert review of respiratory medicine Pub Date : 2026-05-01 Epub Date: 2025-12-11 DOI: 10.1080/17476348.2025.2596919

Clare Tiedeman, Ian Pavord

{"title":"Understanding the relationship between eosinophils and chronic obstructive pulmonary disease. A new dawn?","authors":"Clare Tiedeman, Ian Pavord","doi":"10.1080/17476348.2025.2596919","DOIUrl":"10.1080/17476348.2025.2596919","url":null,"abstract":"Introduction: Chronic obstructive pulmonary disease (COPD) is a leading cause of global morbidity and mortality. It is a complex and heterogeneous condition defined by the presence of an incompletely reversible airflow obstruction.Area covered: Airway inflammation and remodeling are central to the pathogenesis of this airflow limitation, and eosinophilic or type 2 inflammation has emerged as a measurable and treatable therapeutic target in those patients in whom it is identified. This review addresses the role of type 2 inflammation in COPD pathogenesis as well as current and future therapeutic options.Expert opinion: The last 15 years has seen the emergence of a precision medicine, type-2 biomarker directed approach to the use of inhaled corticosteroids in COPD, resulting in better targeting of treatment and an increased benefit/risk ratio. We have also seen the approval of first biological therapy against type 2 inflammation in COPD. There is increasing interest in biomarker directed early intervention to prevent progression or even the development of COPD.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"569-577"},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145710563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bidirectional relationships between depression and asthma. 抑郁症和哮喘之间的双向关系。

IF 2.7

Expert review of respiratory medicine Pub Date : 2026-05-01 Epub Date: 2025-12-05 DOI: 10.1080/17476348.2025.2600111

Brittany Duchene, Anne E Dixon

{"title":"Bidirectional relationships between depression and asthma.","authors":"Brittany Duchene, Anne E Dixon","doi":"10.1080/17476348.2025.2600111","DOIUrl":"10.1080/17476348.2025.2600111","url":null,"abstract":"Introduction: Both asthma and depression are common diseases that significantly contribute to morbidity and mortality worldwide.Area covered: This review was conducted through PubMed as a search engine and discusses the similarities with respect to epidemiology, contributing factors and disease pathogenesis for both depression and asthma. The goal of this review was to assess the available evidence on the links between asthma and depression. These diseases share common epidemiologic characteristics including an increased prevalence in higher income countries, and each is an independent risk factor for development of the other. They share common risk factors including genetic, maternal, and socioeconomic factors. Common pathophysiologic mechanisms in asthma and depression include similar cytokine signaling pathways. Despite the striking similarities in terms of epidemiology, risk factors, and pathophysiologic pathways, few studies have investigated the effects of treating depression on asthma outcomes. The intersection between asthma and depression is remarkable and the available literature suggests treatment of co-morbid depression may improve asthma outcomes. Further investigation into the treatment of depression in asthma is warranted.Expert opinion: Understanding the connection between depressive symptoms and asthma is important for improving asthma outcomes. High-quality studies assessing anti-depressant therapy in those with asthma and depressive symptoms are needed.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"523-533"},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145673216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A clinician's guide to managing multidrug-resistant tuberculosis in children and adolescents. 儿童和青少年耐多药结核病临床医生管理指南。

IF 2.7

Expert review of respiratory medicine Pub Date : 2026-05-01 Epub Date: 2025-11-23 DOI: 10.1080/17476348.2025.2590154

Ingrid Burkhardt, Florian Götzinger, Lahia Iipumbu, Elizabeth Whittaker, Gunar Günther, James A Seddon

{"title":"A clinician's guide to managing multidrug-resistant tuberculosis in children and adolescents.","authors":"Ingrid Burkhardt, Florian Götzinger, Lahia Iipumbu, Elizabeth Whittaker, Gunar Günther, James A Seddon","doi":"10.1080/17476348.2025.2590154","DOIUrl":"10.1080/17476348.2025.2590154","url":null,"abstract":"Introduction: A small fraction of the estimated 25,000-30000 children (<15 years) who develop multidrug-resistant (MDR) tuberculosis (TB) globally every year are diagnosed and started on appropriate treatment. However, recent years have brought rapid changes to diagnostics, prevention, and treatment strategies.Areas covered: We present current data on pediatric and adolescent MDR-TB combined with expert opinion to guide the reader through the pediatric and adolescent MDR-TB care cascade. This includes background information and practical guidance on the disease, the epidemiology, diagnostics, treatment options, and post MDR-TB sequalae. We also address the special circumstances of adolescents, comorbidities, and the socioeconomic impact of MDR-TB. PubMed was searched for suitable articles and national and international guidelines were reviewed.Expert opinion: The roll-out of low complexity molecular diagnostics and advanced techniques, such as targeted next-generation sequencing, have the potential to rapidly diagnose children and adolescents with MDR-TB. The recently introduced short-all oral regimens provide safer and shorter treatment options. The effectiveness of levofloxacin as MDR-TB preventive treatment has been demonstrated. However, wide implementation of such new and advanced tools is still pending and improvements in diagnostics are crucial to increasing the proportion of children and adolescents with MDR-TB being diagnosed.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"475-490"},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145544438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Small RNA-based formulations in precision cut lung slices - is there an alternative for in vivo/in vitro studies? 精确切割肺切片中的小rna制剂-体内/体外研究是否有替代方案？

IF 2.7

Expert review of respiratory medicine Pub Date : 2026-05-01 Epub Date: 2025-12-08 DOI: 10.1080/17476348.2025.2600109

Joanna Nowakowska-Lewicka, Aleksandra Szczepankiewicz

{"title":"Small RNA-based formulations in precision cut lung slices - is there an alternative for in vivo/in vitro studies?","authors":"Joanna Nowakowska-Lewicka, Aleksandra Szczepankiewicz","doi":"10.1080/17476348.2025.2600109","DOIUrl":"10.1080/17476348.2025.2600109","url":null,"abstract":"Introduction: Precision cut lung slices (PCLS) are ex vivo models to study lung diseases. They have numerous advantages related to the presence of different cell types and extracellular matrix. They are an excellent platform to study the biological effects of delivering small molecules with therapeutic potential, such as non-coding RNAs. The aim of this review is to summarize the miRNA and siRNA research on the PCLS model to date and consider therapeutic potential of the proposed solutions.Areas covered: The review focuses on the methodological aspects of delivery of RNA-based formulations, such as miRNA and siRNA, in the PCLSs model. It covers the area of RNA/miRNA isolation from PCLSs and methods of delivering miRNA and siRNA to PCLSs. Analysis of the reported solutions indicated the need for standardization, regarding the information on transfection efficacy at the RNA and protein levels is incomplete.Expert opinion: PCLSs are a promising model for studying small RNA-based drug delivery systems. However, existing models require consistent criteria and methods to assess the biological effect. Because of the heterogeneity of PCLS slices within the single studies, future experiments would benefit from including more independent replicates performed using different methods, in order to improve their reproducibility.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"535-541"},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145679806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adult asthma in Greece: prevalence, comorbidities, and risk factors. 希腊成人哮喘：患病率、合并症和危险因素

IF 2.7

Expert review of respiratory medicine Pub Date : 2026-05-01 Epub Date: 2025-11-29 DOI: 10.1080/17476348.2025.2595726

Ioannis Tomos, Georgia Vourli, Eleni Peppa, Antonia Trichopoulou

{"title":"Adult asthma in Greece: prevalence, comorbidities, and risk factors.","authors":"Ioannis Tomos, Georgia Vourli, Eleni Peppa, Antonia Trichopoulou","doi":"10.1080/17476348.2025.2595726","DOIUrl":"10.1080/17476348.2025.2595726","url":null,"abstract":"Introduction: Asthma still represents a crucial public health challenge with significant health consequences. The study aims to estimate the prevalence of physician-diagnosed self-reported asthma in Greece and to unravel comorbid conditions and risk factors.Research design and methods: The HYDRIA survey was the first national project on the health of the population in Greece. Data regarding demographic, lifestyle characteristics, and medical history were recorded through personal interviews from June 2013 to December 2014. Weighting factors were applied to ensure national representativeness of results.Results: The study includes 4011 men and women. The estimated prevalence of self-reported physician-diagnosed asthma was 8.6% (95% CI: 7.5-9.8%). The most frequent comorbidity was allergic rhinitis, reaching a prevalence of 47.3%. Individuals with asthma reported a significantly higher percentage of perceived restrictions in daily activities (p-value < 0.001). They presented double the risk of having restrictions [2.04 (95% CI: 1.52-2.74); p-value < 0.001]. Age and atopy were significant predictors, however, an interaction indicated that the effect of atopy decreases with age (p for interaction = 0.037).Conclusions: The estimated prevalence of self-reported physician-diagnosed asthma in Greece is 8.6%. Atopy, especially in young age, and age represent risk factors for asthma. Patients with asthma experience double the risk of having restrictions on daily activities compared to individuals without asthma.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":" ","pages":"601-608"},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145598391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0