Expert review of respiratory medicine最新文献_第6页

Central sleep apnea: emphasizing recognition and differentiation. 中枢性睡眠呼吸暂停：强调识别和区分。

Expert review of respiratory medicine Pub Date : 2024-05-01 Epub Date: 2024-06-18 DOI: 10.1080/17476348.2024.2369256

Dries Testelmans, Alexandros Kalkanis, Dimitrios Papadopoulos, Saartje Demolder, Bertien Buyse

{"title":"Central sleep apnea: emphasizing recognition and differentiation.","authors":"Dries Testelmans, Alexandros Kalkanis, Dimitrios Papadopoulos, Saartje Demolder, Bertien Buyse","doi":"10.1080/17476348.2024.2369256","DOIUrl":"10.1080/17476348.2024.2369256","url":null,"abstract":"Introduction: Central sleep apnea (CSA) is a sleep-related breathing disorder in which the effort to breathe is intermittently diminished or absent. CSA is a common disorder among patients with different cardiovascular disorders, including heart failure. In addition, a growing number of medications have been shown to induce CSA and CSA can emerge after initiation of treatment for obstructive sleep apnea. Accumulating evidence shows that CSA is a heterogeneous disorder with individual differences in clinical and biological characteristics and/or underlying pathophysiological mechanisms.Areas covered: This narrative review offers an overview of the diagnostic aspects and classification of CSA, with an emphasis on heart failure patients, patients with CSA due to a medication and treatment-emergent CSA. The importance of evaluation of prognostic biomarkers in patients with different types of CSA is discussed. This narrative review synthesizes literature on CSA sourced from the PubMed database up to February 2024.Expert opinion: CSA presents a remarkably diverse disorder, with treatment modalities exhibiting potentially varied efficacy across its various phenotypes. This highlights the imperative for tailored management strategies that are rooted in phenotype classification.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141328242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of smoking on bronchiectasis and its comorbidities. 吸烟对支气管扩张及其合并症的影响。

Expert review of respiratory medicine Pub Date : 2024-05-01 Epub Date: 2024-06-24 DOI: 10.1080/17476348.2024.2369716

David de la Rosa-Carrillo, José Ignacio de Granda-Orive, Layla Diab Cáceres, Fernando Gutiérrez Pereyra, Beatriz Raboso Moreno, Miguel-Ángel Martínez-García, Guillermo Suárez-Cuartin

{"title":"The impact of smoking on bronchiectasis and its comorbidities.","authors":"David de la Rosa-Carrillo, José Ignacio de Granda-Orive, Layla Diab Cáceres, Fernando Gutiérrez Pereyra, Beatriz Raboso Moreno, Miguel-Ángel Martínez-García, Guillermo Suárez-Cuartin","doi":"10.1080/17476348.2024.2369716","DOIUrl":"10.1080/17476348.2024.2369716","url":null,"abstract":"Introduction: Bronchiectasis, characterized by irreversible bronchial dilatation, is a growing global health concern with significant morbidity. This review delves into the intricate relationship between smoking and bronchiectasis, examining its epidemiology, pathophysiology, clinical manifestations, and therapeutic approaches. Our comprehensive literature search on PubMed utilized MESH terms including 'smoking,' 'smoking cessation,' 'bronchiectasis,' and 'comorbidities' to gather relevant studies.Areas covered: This review emphasizes the role of smoking in bronchiectasis development and exacerbation by compromising airways and immune function. Interconnected comorbidities, including chronic obstructive pulmonary disease, asthma, and gastroesophageal reflux disease, create a detrimental cycle affecting patient outcomes. Despite limited studies on smoking cessation in bronchiectasis, the review stresses its importance. Advocating for tailored cessation programs, interventions like drainage, bronchodilators, and targeted antibiotics are crucial to disrupting the inflammatory-infection-widening cycle.Expert opinion: The importance of smoking cessation in bronchiectasis management is paramount due to its extensive negative impact on related conditions. Proactive cessation programs utilizing technology and targeted education for high-risk groups aim to reduce smoking's impact on disease progression and related comorbidities. In conclusion, a personalized approach centered on smoking cessation is deemed vital for bronchiectasis, aiming to improve outcomes and enhance patients' quality of life in the face of this complex respiratory condition.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141422261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving early diagnosis of bronchopulmonary dysplasia. 改善支气管肺发育不良的早期诊断。

Expert review of respiratory medicine Pub Date : 2024-05-01 Epub Date: 2024-06-14 DOI: 10.1080/17476348.2024.2367584

Oishi Sikdar, Christopher Harris, Anne Greenough

{"title":"Improving early diagnosis of bronchopulmonary dysplasia.","authors":"Oishi Sikdar, Christopher Harris, Anne Greenough","doi":"10.1080/17476348.2024.2367584","DOIUrl":"10.1080/17476348.2024.2367584","url":null,"abstract":"Introduction: Bronchopulmonary disease (BPD) is associated with long-term neurodevelopmental and cardiorespiratory complications, often requiring significant use of resources. To reduce this healthcare burden, it is essential that those at high risk of BPD are identified early so that strategies are introduced to prevent disease progression. Our aim was to discuss potential methods for improving early diagnosis in the first week after birth.Areas covered: A narrative review was undertaken. The search strategy involved searching PubMed, Embase and Cochrane databases from 1967 to 2024. The results of potential biomarkers and imaging modes are discussed. Furthermore, the value of scoring systems is explored.Expert opinion: BPD occurs as a result of disruption to pulmonary vascular and alveolar development, thus abnormal levels of factors regulating those processes are promising avenues to explore with regard to early detection of high-risk infants. Data from twin studies suggests genetic factors can be attributed to 82% of the observed difference in moderate to severe BPD, but large genome-wide studies have yielded conflicting results. Comparative studies are required to determine which biomarker or imaging mode may most accurately diagnose early BPD development. Models which include the most predictive factors should be evaluated going forward.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141322187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Type-2 severe asthma comorbidities in the era of biologics: time to rethink clinical response? 生物制剂时代的 2 型重症哮喘合并症：是时候重新思考临床对策了吗？

Expert review of respiratory medicine Pub Date : 2024-05-01 Epub Date: 2024-06-11 DOI: 10.1080/17476348.2024.2365841

Andrea Portacci, Silvano Dragonieri, Giovanna Elisiana Carpagnano

{"title":"Type-2 severe asthma comorbidities in the era of biologics: time to rethink clinical response?","authors":"Andrea Portacci, Silvano Dragonieri, Giovanna Elisiana Carpagnano","doi":"10.1080/17476348.2024.2365841","DOIUrl":"10.1080/17476348.2024.2365841","url":null,"abstract":"Introduction: The use of monoclonal antibodies in patients with severe asthma has led clinicians to explore new levels of clinical improvement, as testified by the growing interest on clinical remission achievement. In this context, a major role is played by asthma-related comorbidities, which can influence asthma pathophysiology and treatment response.Areas covered: In this special report, we highlighted how asthma-related comorbidities could deeply affect monoclonal antibody response as well as clinical remission achievement. As examples, we provided data from clinical trials and real-life experiences involving patients with severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP), eosinophilic granulomatosis with polyangiitis (EGPA) or bronchiectasis.Expert opinion: Comorbidities associated with severe asthma development should be carefully assessed in everyday clinical practice, even with the help of new diagnostic technologies, artificial intelligence and multidisciplinary teams. Future studies should address the role of comorbidities in remission achievement, describing how these diseases could generate new trajectories of clinical and functional response in patient treated with monoclonal antibodies.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141285732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The influenza landscape and vaccination coverage in older adults during the SARS-Cov-2 pandemic: data from Several European Countries and Israel. SARS-Cov-2 大流行期间老年人的流感状况和疫苗接种率：来自几个欧洲国家和以色列的数据。

Expert review of respiratory medicine Pub Date : 2024-04-23 DOI: 10.1080/17476348.2024.2340470

George Kassianos, Jean-Marie Cohen, R. Čivljak, N. Davidovitch, Oana Falup Pecurariu, Filipe Froes, Andrei Galev, Inga Ivaskeviciene, Kadri Kõivumägi, Zuzana Kristufkova, Ernest Kuchar, Jan Kyncl, H. Maltezou, Miloš Marković, A. Nitsch-Osuch, Raul Ortiz de Lejarazu, Alessandro Rossi, Jörg Schelling, G. A. van Essen, D. Zavadska

{"title":"The influenza landscape and vaccination coverage in older adults during the SARS-Cov-2 pandemic: data from Several European Countries and Israel.","authors":"George Kassianos, Jean-Marie Cohen, R. Čivljak, N. Davidovitch, Oana Falup Pecurariu, Filipe Froes, Andrei Galev, Inga Ivaskeviciene, Kadri Kõivumägi, Zuzana Kristufkova, Ernest Kuchar, Jan Kyncl, H. Maltezou, Miloš Marković, A. Nitsch-Osuch, Raul Ortiz de Lejarazu, Alessandro Rossi, Jörg Schelling, G. A. van Essen, D. Zavadska","doi":"10.1080/17476348.2024.2340470","DOIUrl":"https://doi.org/10.1080/17476348.2024.2340470","url":null,"abstract":"INTRODUCTION\u0000The Raise Awareness of Influenza Strategies in Europe (RAISE) group gathered information about the healthcare burden of influenza (hospitalizations, intensive care unit [ICU] admissions, and excess deaths), surveillance systems, and the vaccine coverage rate (VCR) in older adults in 18 European countries and Israel.\u0000\u0000\u0000AREAS COVERED\u0000Published medical literature and official medical documentation on the influenza disease burden in the participating countries were reviewed from 2010/11 until the 2022/23 influenza seasons. Information on the framework for monitoring the disease burden and the provision for ensuring older adults had access to vaccination in their respective countries was provided. Data on influenza VCR in older adults were collected for the 2019/20 to 2022/23 influenza seasons. Data are reported descriptively.\u0000\u0000\u0000EXPERT OPINION\u0000Influenza presents a significant healthcare burden in older adults. Reporting outcomes across participating countries is heterogeneous, highlighting the need for standardized approaches. Although older adults receive free influenza vaccination, vaccine uptake is highly variable among countries. Moreover, hospitalization rates remain high even in countries reporting a high VCR. Increased awareness and education on the burden of disease and the broader use of improved influenza vaccines for older adults may help reduce the disease burden on this population.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140670188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preoperative frailty screening in elderly patients with non-small cell lung cancer surgery: an essential step for a good surgical outcome. 对接受非小细胞肺癌手术的老年患者进行术前虚弱筛查：获得良好手术效果的必要步骤。

Expert review of respiratory medicine Pub Date : 2024-03-01 Epub Date: 2024-05-07 DOI: 10.1080/17476348.2024.2349579

Radu Iacobescu, Sabina Antonela Antoniu, Alina Delia Popa, Mariana Pavel-Tanase, Teodora Alexa Stratulat

{"title":"Preoperative frailty screening in elderly patients with non-small cell lung cancer surgery: an essential step for a good surgical outcome.","authors":"Radu Iacobescu, Sabina Antonela Antoniu, Alina Delia Popa, Mariana Pavel-Tanase, Teodora Alexa Stratulat","doi":"10.1080/17476348.2024.2349579","DOIUrl":"10.1080/17476348.2024.2349579","url":null,"abstract":"Introduction: Non-small cell lung cancer (NSCLC) is a disease commonly diagnosed in the elderly, often in advanced stages. However, elderly patients with lung cancer can benefit from surgery, provided that postoperative risks are assessed appropriately before surgery. Frailty is a measure of age-related impaired functional status and a predictor of mortality and morbidity. However, its importance as a preoperative marker is not well defined.Areas covered: This systematic review discusses the importance of preoperative frailty screening in elderly patients with NSCLC. A literature search was performed on the MEDLINE database in June 2023, and relevant studies on frailty or preoperative assessment of NSCLC which were published between 2000 and 2023 were retained and discussed in this review.Expert opinion: Among the types of existing methods used to assess frailty those on the geriatric assessment seem to be the most appropriate; however, they are unable to fully capture the 'surgical' frailty; thus, other instruments should be developed and validated in NSCLC.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140869510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extrapulmonary manifestations of pulmonary arterial hypertension. 肺动脉高压的肺外表现。

Expert review of respiratory medicine Pub Date : 2024-03-01 Epub Date: 2024-05-30 DOI: 10.1080/17476348.2024.2361037

Navneet Singh, Nadine Al-Naamani, Mary Beth Brown, Gary Marshall Long, Thenappan Thenappan, Soban Umar, Corey E Ventetuolo, Tim Lahm

{"title":"Extrapulmonary manifestations of pulmonary arterial hypertension.","authors":"Navneet Singh, Nadine Al-Naamani, Mary Beth Brown, Gary Marshall Long, Thenappan Thenappan, Soban Umar, Corey E Ventetuolo, Tim Lahm","doi":"10.1080/17476348.2024.2361037","DOIUrl":"10.1080/17476348.2024.2361037","url":null,"abstract":"Introduction: Extrapulmonary manifestations of pulmonary arterial hypertension (PAH) may play a critical pathobiological role and a deeper understanding will advance insight into mechanisms and novel therapeutic targets. This manuscript reviews our understanding of extrapulmonary manifestations of PAH.Areas covered: A group of experts was assembled and a complimentary PubMed search performed (October 2023 - March 2024). Inflammation is observed throughout the central nervous system and attempts at manipulation are an encouraging step toward novel therapeutics. Retinal vascular imaging holds promise as a noninvasive method of detecting early disease and monitoring treatment responses. PAH patients have gut flora alterations and dysbiosis likely plays a role in systemic inflammation. Despite inconsistent observations, the roles of obesity, insulin resistance and dysregulated metabolism may be illuminated by deep phenotyping of body composition. Skeletal muscle dysfunction is perpetuated by metabolic dysfunction, inflammation, and hypoperfusion, but exercise training shows benefit. Renal, hepatic, and bone marrow abnormalities are observed in PAH and may represent both end-organ damage and disease modifiers.Expert opinion: Insights into systemic manifestations of PAH will illuminate disease mechanisms and novel therapeutic targets. Additional study is needed to understand whether extrapulmonary manifestations are a cause or effect of PAH and how manipulation may affect outcomes.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141156160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measurement of thoraco-abdominal synchrony using respiratory inductance plethysmography: technical aspects and a proposal to overcome its limitations. 使用呼吸电感胸透测量胸腹同步性：技术方面和克服其局限性的建议。

Expert review of respiratory medicine Pub Date : 2024-03-01 Epub Date: 2024-06-07 DOI: 10.1080/17476348.2024.2363058

Javier Sayas, Cristina Lalmolda, Marta Corral, Pablo Flórez, Ana Hernández-Voth, Jean Paul Janssens, Claudio Rabec, Bruno Langevin, Frédéric Lofaso, Annalisa Carlucci, Claudia Llontop, Joao Carlos Winck, Jesús González Bermejo, Manel Lujan

{"title":"Measurement of thoraco-abdominal synchrony using respiratory inductance plethysmography: technical aspects and a proposal to overcome its limitations.","authors":"Javier Sayas, Cristina Lalmolda, Marta Corral, Pablo Flórez, Ana Hernández-Voth, Jean Paul Janssens, Claudio Rabec, Bruno Langevin, Frédéric Lofaso, Annalisa Carlucci, Claudia Llontop, Joao Carlos Winck, Jesús González Bermejo, Manel Lujan","doi":"10.1080/17476348.2024.2363058","DOIUrl":"10.1080/17476348.2024.2363058","url":null,"abstract":"Background: Thoraco-abdominal asynchrony (TAA) is usually assessed by respiratory inductance plethysmography. The main parameter used for its assessment is the calculation of the phase angle based on Lissajous plots. However, there are some mathematical limitations to its use.Research design and methods: Sequences of five breaths were selected from a) normal subjects, b) COPD patients, both at rest and during exercise, and c) patients with obstructive apnea syndrome. Automated analysis was performed calculating phase angle, loop rotation (clockwise or counterclockwise), global phase delay and loop area. TAA severity was estimated quantitatively and in subgroups.Results: 2290 cycles were analyzed (55% clockwise rotation). Phase angle ranged from -86.90 to + 88.4 degrees, while global phase delay ranged from -179.75 to + 178.54. Despite a good correlation with global phase delay (p < 0.01, ANOVA test), phase angle and loop area were not able to correctly classify breaths with severe deviation and paradoxical movements (p=ns, Bonferroni post hoc test).Conclusions: Global phase delay covers the whole spectrum of TAA situations in a single value. It may be a relevant parameter for diagnosis and follow-up of clinical conditions leading to TAA.Clinical trial registration: The trial from which the traces were obtained was registered at ClinicalTrials.gov ;(identifier: NCT04597606).","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141201572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanofiberous facemasks as protectives against pandemic respiratory viruses. 纳米纤维面罩作为预防大流行性呼吸道病毒的保护剂。

Expert review of respiratory medicine Pub Date : 2024-03-01 Epub Date: 2024-05-22 DOI: 10.1080/17476348.2024.2356601

Merna H Emam, Reham S Elezaby, Shady A Swidan, Rania M Hathout

{"title":"Nanofiberous facemasks as protectives against pandemic respiratory viruses.","authors":"Merna H Emam, Reham S Elezaby, Shady A Swidan, Rania M Hathout","doi":"10.1080/17476348.2024.2356601","DOIUrl":"10.1080/17476348.2024.2356601","url":null,"abstract":"Introduction: Wearing protective face masks and respirators has been a necessity to reduce the transmission rate of respiratory viruses since the outbreak of the coronavirus (COVID-19) disease. Nevertheless, the outbreak has revealed the need to develop efficient air filter materials and innovative anti-microbial protectives. Nanofibrous facemasks, either loaded with antiviral nanoparticles or not, are very promising personal protective equipment (PPE) against pandemic respiratory viruses.Areas covered: In this review, multiple types of face masks and respirators are discussed as well as filtration mechanisms of particulates. In this regard, the limitations of traditional face masks were summarized and the advancement of nanotechnology in developing nanofibrous masks and air filters was discussed. Different methods of preparing nanofibers were explained. The various approaches used for enhancing nanofibrous face masks were covered.Expert opinion: Although wearing conventional face masks can limit viral infection spread to some extent, the world is in great need for more protective face masks. Nanofibers can block viral particles efficiently and can be incorporated into face masks in order to enhance their filtration efficiency. Also, we believe that other modifications such as addition of antiviral nanoparticles can significantly increase the protection power of facemasks.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Respiratory training effects in Long COVID-19 patients: a systematic review and meta-analysis. Long COVID-19 患者的呼吸训练效果：系统回顾和荟萃分析。

Expert review of respiratory medicine Pub Date : 2024-03-01 Epub Date: 2024-05-27 DOI: 10.1080/17476348.2024.2358933

Andrés Calvache-Mateo, Gregory Reychler, Alejandro Heredia-Ciuró, Javier Martín-Núñez, Araceli Ortiz-Rubio, Alba Navas-Otero, Marie Carmen Valenza

{"title":"Respiratory training effects in Long COVID-19 patients: a systematic review and meta-analysis.","authors":"Andrés Calvache-Mateo, Gregory Reychler, Alejandro Heredia-Ciuró, Javier Martín-Núñez, Araceli Ortiz-Rubio, Alba Navas-Otero, Marie Carmen Valenza","doi":"10.1080/17476348.2024.2358933","DOIUrl":"10.1080/17476348.2024.2358933","url":null,"abstract":"Introduction: To date, it is unknown whether respiratory training interventions can benefit Long COVID-19 patients. The main objective was to analyze the effects of respiratory training on patients with Long COVID-19, concretely on respiratory muscle strength, lung function, dyspnea, and functional capacity.Methods: We performed a systematic review following PRISMA statement using PubMed, Scopus, and PEDro (last search November 2023). The risk of bias was assessed using the Cochrane tool. We included randomized controlled trials testing the effect of respiratory training interventions in Long COVID-19 patients versus no intervention, control, or placebo intervention. The data was pooled, and a meta-analysis was complete.Results: We selected 7 studies, which included 572 patients. Meta-analysis results show significant differences in favor of respiratory training in respiratory muscle strength (MD = 13.71; 95% CI = 5.41; 22; p = 0.001), dyspnea (SDM = 1.39; 95% CI = 0.33; 2.46; p = 0.01) and functional capacity (SDM = 0.90; 95% CI = 0.37; 1.43; p = 0.0009), but not in lung function (MD = 0.28; 95%CI = -0.27; 0.83; p = 0.32).Conclusion: The results of this systematic review with meta-analysis suggest that respiratory training improves respiratory muscle strength and functional capacity in Long COVID-19 patients, as well as dyspnea if combined with therapeutic exercise. However, respiratory training does not improve lung function in these patients.Review registration prospero identifier: CRD42022371820.","PeriodicalId":94007,"journal":{"name":"Expert review of respiratory medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141156142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0