European journal of breast health最新文献

{"title":"Is Breast Imaging in Male Patients With Benign Lumps Necessary? A Retrospective Study to Assess Concordance Between Clinical Diagnosis and Imaging Findings.","authors":"Cleofina Furtado,&nbsp;Aleksandra Stankiewicz,&nbsp;Jana Klcova,&nbsp;Mahrukh Khan,&nbsp;Saba Bajwa,&nbsp;Zatinahhayu Mohd Isa","doi":"10.4274/ejbh.galenos.2023.2023-5-2","DOIUrl":"https://doi.org/10.4274/ejbh.galenos.2023.2023-5-2","url":null,"abstract":"<p><strong>Objective: </strong>Breast imaging for male patients is a controversial topic due to the high prevalence of gynecomastia compared to male breast cancer. Worldwide, men are undergoing more breast imaging despite the low incidence of male breast cancer. Gynecomastia is a benign condition, but the anxiety it causes and unnecessary medical costs are still high.</p><p><strong>Materials and methods: </strong>In accordance with Royal College of Radiology guidelines, a retrospective study was performed in two cycles to determine if mammography or ultrasound should be included in the workup of male patients who were referred to a breast care unit for a lump that was deemed benign by doctors.</p><p><strong>Results: </strong>There was 100% concordance between clinical diagnosis and imaging findings.</p><p><strong>Conclusion: </strong>In this population imaging was not necessary in cases of probable gynecomastia and benign conditions found during a clinical assessment. Standardised patient assessment methods can improve care and ensure accurate evaluation.</p>","PeriodicalId":93996,"journal":{"name":"European journal of breast health","volume":"19 4","pages":"304-310"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546800/pdf/ejbh-19-304.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41175847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Complication Following Breast Conserving Surgery: Pyoderma Gangrenosum.","authors":"Glenn Costa,&nbsp;Serkan İlgün,&nbsp;David Pisani,&nbsp;John Agius","doi":"10.4274/ejbh.galenos.2023.2023-6-1","DOIUrl":"10.4274/ejbh.galenos.2023.2023-6-1","url":null,"abstract":"<p><p>Pyoderma gangrenosum (PG) after breast-conserving surgery is rare, and its diagnosis is often delayed because of the similarity to wound infection and the broad differential diagnosis for PG, making it a diagnosis of exclusion. A 60-year-old woman who underwent breast conserving surgery and sentinel lymph node biopsy for invasive breast carcinoma presented with increasing erythema, fever and serosanguinous discharge in the lower outer quadrant of the right breast at the site of tumour excision on postoperative day (POD) 9. Fever persisted despite antibiotics and the patient was noted to have leucocytosis (0.9 x 10⁹/L), neutrophilia (37.8 x 10⁹/L) and elevated C-reactive protein levels (136 μg/mL) on POD 16. Microbiology and blood culture results were negative but the breast ulcer continued to expand at a rate of 1-2 cm a day. The patient underwent surgical debridement on POD 21 to rule out necrotising soft tissue infection. Persistent ulcer progression, despite debridement and antibiotics, led to clinical suspicion of PG and the patient was started on prednisolone and cyclosporin. A rapid response was seen with treatment and an optimum healing process was noted over the subsequent three-month follow-up period. Early suspicion, careful macroscopic evaluation of disease progression and appropriate use of immunosuppressive therapy are important for the management of PG. Prompt initiation of immunosuppressive therapy may avoid unnecessary treatment and aggravation of the surgical wound.</p>","PeriodicalId":93996,"journal":{"name":"European journal of breast health","volume":"19 4","pages":"331-334"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546801/pdf/ejbh-19-331.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41180772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does a 40% Cut-off Point for Ki-67 Expression Have a Role in Identifying the Development of Distant Metastasis Within 2 Years in Locally Advanced Triple Negative Breast Cancer Patients?","authors":"Kelvin Setiawan,&nbsp;Ida Bagus Suryawisesa,&nbsp;I Ketut Widiana,&nbsp;I Wayan Sudarsa","doi":"10.4274/ejbh.galenos.2023.2023-4-5","DOIUrl":"https://doi.org/10.4274/ejbh.galenos.2023.2023-4-5","url":null,"abstract":"<p><strong>Objective: </strong>Triple negative breast cancer (TNBC) has a higher proportion of patients with distant recurrence or metastasis. Ki-67 has been suggested as an essential factor in cancer grading and prognostic evaluation, although there is still a debate regarding the Ki-67 cut-off value in TNBC. The aim of this study was to determine the role of Ki-67 expression using a 40% cut-off point as a risk factor for developing distant metastasis within two years in patients with TNBC.</p><p><strong>Materials and methods: </strong>This analytical observational study was conducted with a case-control design from January 2021-2022. Subjects were divided into two groups (metastasis within two years or more than two years after diagnosis). Bivariate analysis was conducted using chi-square test and odds ratio (OR) was also analyzed.</p><p><strong>Results: </strong>A total of 66 subjects were included. In patients with metastasized TNBC and a Ki-67 expression of ≥40%, 29 patients (55.8%) had metastasis occurring in ≤2 years and 23 patients (44.2%) had metastasis occurring in >2 years; in patients with metastasized TNBC and a Ki-67 expression of <40%, 4 patients (28.6%) had metastasis occurring in ≤2 years and 10 patients (71.4%) had metastasis occurring in >2 years. Chi-square analysis (<i>p</i> = 0.071) indicated no significant association between patients with Ki-67 expression of ≥40% and <40% with metastasis within 2 years [OR 3.152 (confidence interval: 95% 0.875-11.362)].</p><p><strong>Conclusion: </strong>Ki-67 protein expression of over 40% in patients with locally-advanced TNBC does not indicate a greater risk of distant metastasis in the first two years after diagnosis.</p>","PeriodicalId":93996,"journal":{"name":"European journal of breast health","volume":"19 4","pages":"274-278"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546796/pdf/ejbh-19-274.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41161066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Future of Breast Radiology.","authors":"Erkin Arıbal","doi":"10.4274/ejbh.galenos.2023.2023-8-3","DOIUrl":"10.4274/ejbh.galenos.2023.2023-8-3","url":null,"abstract":"<p><p>The landscape of breast imaging has transformed significantly since mammography's introduction in the 1960s, accelerated by ultrasound and imageguided biopsies in the 1990s. The emergence of magnetic resonance imaging (MRI) in the 2000s added a valuable dimension to advanced imaging. Multimodality and multiparametric imaging have firmly established breast radiology's pivotal role in managing breast disorders. A shift from conventional to digital radiology emerged in the late 20th and early 21st centuries, enabling advanced techniques like digital breast tomosynthesis, contrast-enhanced mammography, and artificial intelligence (AI) integration. AI's impending integration into breast radiology may enhance diagnostics and workflows. It involves computer-aided diagnosis (CAD) algorithms, workflow support algorithms, and data processing algorithms. CAD systems, developed since the 1980s, optimize cancer detection rates by addressing false positives and negatives. Radiologists' roles will evolve into specialized clinicians collaborating with AI for efficient patient care and utilizing advanced techniques with multiparametric imaging and radiomics. Wearable technologies, non-contrast MRI, and innovative modalities like photoacoustic imaging show potential to enhance diagnostics. Imaging-guided therapy, notably cryotherapy, and theranostics, gains traction. Theranostics, integrating therapy and diagnostics, holds potential for precise treatment. Advanced imaging, AI, and novel therapies will revolutionize breast radiology, offering refined diagnostics and personalized treatments. Personalized screening, AI's role, and imaging-guided therapies will shape the future of breast radiology.</p>","PeriodicalId":93996,"journal":{"name":"European journal of breast health","volume":"19 4","pages":"262-266"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546805/pdf/ejbh-19-262.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41169253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the Effect of Women's Breast Cancer Worry Levels on Breast Cancer Prevention Behavior.","authors":"Sümeyra Betül Namlı,&nbsp;Sibel Tunç Karaman,&nbsp;Okcan Basat","doi":"10.4274/ejbh.galenos.2023.2023-4-4","DOIUrl":"https://doi.org/10.4274/ejbh.galenos.2023.2023-4-4","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate the extent of worry about breast cancer (BC) amongst a sample of women and to examine the effect of this on behavior to prevent BC.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted in 271 women aged 18 years and above who attended the Family Medicine Outpatient Clinic of a tertiary hospital and met the inclusion criteria. Data were collected using the following tools: Patient Information Form; Breast Cancer Worry Scale (BCWS); Breast Cancer Prevention Behaviors Identification Scale (BCPBIS); and Mammography Processes of Change Scale (MPCS).</p><p><strong>Results: </strong>When evaluated according to BCWS scores (mean 8.43±3.36), the BC worry levels were found to be low. The behavior adopted for prevention was also found to be positive according to BCPBIS (mean 119±15.26) and MPCS (mean 82.38±12.81) scores. A significant correlation was found between the BCWS and both the BCPBIS and MPCS scores, and again between the BCPBIS and MPCS scores (<i>p</i><0.001 for all). There was a correlation with three scale scores in those who had knowledge about BC, and those who had regular clinical breast examination (BE) (<i>p</i><0.05 for all). The BCPBIS score was found to be higher in those aged between 41-65 years, those who had mammography, and performed <i>p</i> self-BE (<i>p</i> = 0.002; <i>p</i><0.001; <i>p</i><0.001, respectively). According to the MPCS score, mammography behaviors was found to be more positive in those who had regular gynecological examinations and those who had mammography (<i>p</i> = 0.08 and <i>p</i> = 0.011).</p><p><strong>Conclusion: </strong>The participants generally had low BC worry levels and had adopted positive behavior for prevention. Being informed about BC and screening and having regular BE increased BC worry. Those with high BC worry, those who had mammography before, those who had knowledge about BC and screening, and those who regularly performed BE showed more positive behaviors toward preventing BC.</p>","PeriodicalId":93996,"journal":{"name":"European journal of breast health","volume":"19 4","pages":"279-286"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546797/pdf/ejbh-19-279.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41109101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Axillary Surgical Attitude Changing with Retrospective Application of <i>ACOSOG Z0011</i> Eligible Criteria: An Institutional Evaluation.","authors":"C Florin Pop,&nbsp;Lea Datin Nziki,&nbsp;Etienne El Helou,&nbsp;Michel Moreau,&nbsp;Magali Radermecker,&nbsp;Denis Larsimont,&nbsp;Isabelle Veys,&nbsp;Filip De Neubourg","doi":"10.4274/ejbh.galenos.2023.2023-6-4","DOIUrl":"10.4274/ejbh.galenos.2023.2023-6-4","url":null,"abstract":"<p><strong>Objective: </strong>Sentinel lymph node biopsy (SLNB) represents the gold standard for axillary surgical staging. The aim of this study was to assess the proportion of axillary lymph node dissection (ALND) that could be avoided after retrospective application of the <i>ACOSOG Z0011</i> criteria and to evaluate the shortterm complications associated with axillary surgery.</p><p><strong>Materials and methods: </strong>We reviewed breast cancer (BC) patients treated by primary breast-conserving surgery from 2012 to 2015. The percentage of SLNB vs ALND performed before and after the application of the <i>ACOSOG Z0011</i> criteria was calculated. Complications were analyzed using crosstabs, with <i>p</i><0.05 considered significant.</p><p><strong>Results: </strong>Two hundred fifty one patients with a median age of 59.3 years were included. BC tumors had a median size of 13 mm and were mostly unifocal (83.9%). There were 30.3% with 1-2 metastatic lymph nodes (MLN). ALND was performed in 44.2%. The patients with 1-2 MLN, had only SLNB in 14.5% of cases. By applying the <i>ACOSOG Z0011</i> criteria, ALND would have been avoided in 40.2% of patients. At least one postoperative complication was reported after SLNB or ALND for 45.7% and 74.7% of patients respectively. Seroma was the most frequent complication, and occurred in 29.3% of cases after SLNB and in 59.5% after ALND.</p><p><strong>Conclusion: </strong>SNLB is the most commonly used axillary surgical staging procedure in this series (55.8%). With a retrospective application of the <i>ACOSOG Z0011</i> criteria in our population, ALND could have been avoided for 40.2% patients. Post-operative complications rate was higher after ALND, with a seroma rate at 59.5%.</p>","PeriodicalId":93996,"journal":{"name":"European journal of breast health","volume":"19 4","pages":"318-324"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546802/pdf/ejbh-19-318.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41157521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment High-Risk Breast Cancer in Older Patients: A Comparative Analysis of PREDICT Scores and TAILORx Risk Categorization.","authors":"Çağlar Ünal,&nbsp;Tolga Özmen,&nbsp;Çetin Ordu,&nbsp;Cihan Uras,&nbsp;Halil Kara,&nbsp;Erhan Gökmen,&nbsp;Mustafa Özdoğan,&nbsp;Orhan Demircan,&nbsp;Kezban Nur Pilancı,&nbsp;Tomris Duymaz,&nbsp;Vahit Özmen","doi":"10.4274/ejbh.galenos.2023.2023-8-5","DOIUrl":"https://doi.org/10.4274/ejbh.galenos.2023.2023-8-5","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the relationship between PREDICT tool overall survival (OS) scores and high-risk patients according to TAILORx risk categorization in elderly hormone reseptor (HR) positive human epidermal growth factor negative early breast-cancer patients.</p><p><strong>Materials and methods: </strong>We conducted a retrospective study, extracting data from medical records of 64 patients diagnosed with breast cancer. A retrospective analysis was performed on all patients who had Oncotype Dx Recurrence Scores across five medical centers between 2017 and 2022. PREDICT scores were defined as calculated 10-year OS rates via PREDICT tool.</p><p><strong>Results: </strong>The median age of the patients was 67, with a range between 65-75 years. Low-risk patients had a slightly higher two PREDICT scores compared to high-risk patients (78% vs. 73%), (81% vs. 77%), which were statistically significant. The progesterone receptor (PR) level was significantly lower in the high-risk group (3.5% vs. 80%). A unit decrease in the PREDICT scores was associated with a 11% increase in the odds of being in the high-risk group. However, these effects weren't statistically significant in the multivariate analysis. A unit decrease in the PR level was significantly associated with increased odds (by 5% in the multivariate analysis) of being in the high-risk group.</p><p><strong>Conclusion: </strong>Our study underscores the importance of using a combination of tools, including the PREDICT tool, PR levels, and TAILORx risk categorization, for a comprehensive risk assessment in these patients, especially in the older population. Accurate risk assessment is crucial for tailoring the treatment and optimizing outcomes in this vulnerable population. Future studies are warranted to further validate these findings in larger cohorts and to explore additional biomarkers and genomic signatures that may aid in the risk assessment and management of breast cancer in older patients.</p>","PeriodicalId":93996,"journal":{"name":"European journal of breast health","volume":"19 4","pages":"325-330"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546806/pdf/ejbh-19-325.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41161065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Mediating Role of Psychological Resilience in the Relationship Between Spiritual Well-Being and Supportive Care Needs in Women With Breast Cancer.","authors":"Özlem Soyer Er,&nbsp;Hamide Nur Erkan","doi":"10.4274/ejbh.galenos.2023.2023-6-5","DOIUrl":"https://doi.org/10.4274/ejbh.galenos.2023.2023-6-5","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to examine the mediating role of psychological resilience as part of the effect of spiritual well-being in the supportive care needs of women with breast cancer.</p><p><strong>Materials and methods: </strong>Cross-sectional design. The Connor-Davidson Resilience Scale Short Form, the Spiritual Well-Being Scale, and the Supportive Care Needs Survey Short Form were completed women with breast cancer treated at the oncology clinic of a university hospital. For the mediation model, Bootstrap methods with PROCESS Macro were used.</p><p><strong>Results: </strong>The study was conducted with 126 breast cancer patients. A significant negative, moderate relationship was found between supportive care needs and psychological resilience (r = -0.560). There was a significant negative, but weak relationship between supportive care needs and spiritual well-being (r = -0.385). The indirect effect of spiritual well-being on supportive care needs was significant, thus, psychological resilience was shown to have a mediating effect on the relationship between spiritual well-being and supportive care needs [b = -0.370, 95% confidence interval (- 0.5568, -0.1911)].</p><p><strong>Conclusion: </strong>Psychological resilience appears to contribute to a reduction in supportive care needs of breast cancer patients by affecting spiritual well-being.</p>","PeriodicalId":93996,"journal":{"name":"European journal of breast health","volume":"19 4","pages":"297-303"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546799/pdf/ejbh-19-297.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41169254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary Breast Pleomorphic Liposarcoma Evaluation With MRI and Pathology: A Rare Case.","authors":"Rana Günöz Cömert,&nbsp;Aysel Bayram,&nbsp;Ravza Yılmaz","doi":"10.4274/ejbh.galenos.2023.2023-5-3","DOIUrl":"https://doi.org/10.4274/ejbh.galenos.2023.2023-5-3","url":null,"abstract":", Yılmaz R. Primary Breast Pleomorphic Liposarcoma Evaluation With MRI and Pathology: A Rare Case. Eur J Breast Health 2023; 19(4): 335-337","PeriodicalId":93996,"journal":{"name":"European journal of breast health","volume":"19 4","pages":"335-337"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546798/pdf/ejbh-19-335.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41166197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}