Ear, nose, & throat journal最新文献

{"title":"Perilymphatic Fistula and Vestibular Dysfunction Requiring Cochlear Implant Programming Intervention: A Case Study.","authors":"Evyn Stewart, Caitlin Gomez, Terence E Imbery, Elias Michaelides, Joshua Sevier","doi":"10.1177/01455613251359173","DOIUrl":"https://doi.org/10.1177/01455613251359173","url":null,"abstract":"<p><p>Cochlear implants (CIs) are effective interventions for treating severe-to-profound sensorineural hearing loss. In patients with complex inner ear anatomy due to conditions such as incomplete partition type II (IP-II) and enlarged vestibular aqueduct, they present unique challenges, increasing the risk of surgical and postoperative complications, including facial nerve stimulation (FNS), cerebrospinal fluid leaks, and vestibular dysfunction. The 32 year-old subject of this case study presented with IP-II and experienced persistent FNS, dizziness, and declining CI performance despite an initial revision surgery and appropriate programming strategies of her processor. Interdisciplinary collaboration between audiology, neurotology, and speech-language pathology helped to identify and address contributing factors to the patient's symptoms. After strategic programming adjustments, including pulse width modification and electrode management in conjunction with aural rehabilitation sessions, the patient's speech perception scores and CI quality of life metrics improved markedly over time, as did her confidence and engagement in social and professional settings. This case highlights a challenging example of CI performance issues in the setting of IP-II and aims to examine how CI programming, in response to anatomical and surgical difficulties, affects patient outcomes in cases involving inner ear malformations.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251359173"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pterygopalatine Fossa Angioleiomyoma: An Atypical, Locally Destructive Presentation of a Rare Pathology.","authors":"Leo Song, Chana R Sachs, Jeffrey D Suh, Jakob L Fischer","doi":"10.1177/01455613251362042","DOIUrl":"https://doi.org/10.1177/01455613251362042","url":null,"abstract":"<p><p>Sinonasal angioleiomyomas (SNALMs) are rare, typically indolent tumors that present as painless, slow-growing nasal masses arising from the nasal septum, inferior turbinate, or nasal vestibule with minimal local invasion. We present a case of a 39 year-old man with no relevant past medical history with a uniquely aggressive case of a SNALM originating in the pterygopalatine fossa (PPF) with expansile erosion of adjacent skull base structures-an unusual radiographic feature for a tumor classically considered nondestructive. Clinically, the patient's presentation with severe ipsilateral posterolateral headaches and rapid-onset nasal obstruction further deviates from the expected course, highlighting an atypical symptom profile not previously associated with SNALMs. Surgical excision of the mass was curative with resolution of headaches and no tumor recurrence at 7 months of follow-up. This case expands the current understanding of the clinical and radiographic spectrum of SNALMs and reinforces the importance of considering them in the differential diagnosis of vascular skull base lesions.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251362042"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid Balloon-Assisted Endoscopic Sinus Surgery for Refractory Chronic Rhinosinusitis in a Pediatric Patient with Cystic Fibrosis: A Case Report.","authors":"Eugene Oh, Oren Saghian, Jason Zar, Beth Osterbauer, Elisabeth H Ference","doi":"10.1177/01455613251361237","DOIUrl":"https://doi.org/10.1177/01455613251361237","url":null,"abstract":"<p><p>The management of refractory chronic rhinosinusitis (CRS) in children with cystic fibrosis (CF) remains a challenge, especially in those who are not candidates for highly effective modulator therapy. These patients often have severe sinus disease that does not improve with medical treatment, requiring surgery as the definitive treatment. We report a case of a 9-year-old female patient with CF and refractory CRS presenting with significant nasal obstruction, postnasal drainage, and frontal headaches that severely impacted her quality of life. A hybrid technique that involved balloon catheter dilation (BCD) along with endoscopic sinus surgery (ESS) allowed the management of complex anatomical problems associated with the severe polyposis, copious purulence, and narrow frontal recesses during the surgery. This improved our ability to visualize the surgical field, minimize blood loss, and better preserve the mucosa, which ultimately led to better surgical and clinical outcomes. Our findings suggest that hybrid BCD-assisted ESS may offer an effective solution to manage severe CRS in pediatric CF patients, particularly for those who have limited therapeutic options.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251361237"},"PeriodicalIF":0.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Stapediovestibular Dislocation with Congenital Duplication of the Tympanic Segment of the Facial Nerve: A Case Report.","authors":"Wen-Chun Wang, Yuan Cheng Liu, Yu-Fu Chou","doi":"10.1177/01455613251360483","DOIUrl":"https://doi.org/10.1177/01455613251360483","url":null,"abstract":"<p><p>External stapediovestibular dislocations are rare and often traumatic. Congenital facial nerve anomalies, as in this case, make reconstruction of the ossicular chain even more challenging.A 37-year-old woman patient presented progressive bilateral hearing loss and aural fullness for 1 month in May 2024. She had suffered a fall from a height of approximately 4 stories in 2017. The audiometry showed bilateral conductive hearing loss with an air-bone gap greater than 50 dB. A temporal bone computed tomography scan showed suspected stapes detachment and facial nerve anomalies in both ears. Right exploratory tympanotomy revealed external stapediovestibular dislocation with duplication of facial nerve in the tympanic segment. A type V tympanoplasty with piston wire insertion was performed. Audiometry after right ear surgery showed closure of the air-bone gap by 42 dB, without vertigo or facial nerve injury.Surgery aims to prevent facial nerve injury while successful restoring hearing loss. The cause of stapediovestibular dislocation is discussed, along with methods for reconstruction of the ossicular chain.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251360483"},"PeriodicalIF":0.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cervical Sympathetic Chain Schwannoma in the Parapharyngeal Space: A Rare Case and Literature Review.","authors":"Alaa Senjab, Omar Al Ayoubi, Grace Tannous, Ahmad Al-Bitar, Arige Alassaf","doi":"10.1177/01455613251361249","DOIUrl":"https://doi.org/10.1177/01455613251361249","url":null,"abstract":"<p><strong>Introduction: </strong>Schwannomas are rare, typically benign tumors arising from Schwann cells. Parapharyngeal space tumors account for only about 0.5% of all head and neck neoplasms, with schwannomas representing ~31% of these. Among these, schwannomas originating from the cervical sympathetic chain (CSC) are particularly rare but clinically important. These tumors grow slowly and often present with vague symptoms such as mild dysphagia, which delays diagnosis. Imaging techniques such as computed tomography (CT) and magnetic resonance imaging aid evaluation. This report presents a rare CSC schwannoma case and reviews 54 others to highlight diagnostic and clinical features.</p><p><strong>Case presentation: </strong>A 44-year-old Arab female presented with a 4-month history of mild dysphagia and right-sided throat discomfort. Physical examination revealed a smooth, non-tender submucosal bulge along the right lateral pharyngeal wall. Contrast-enhanced CT demonstrated a well-circumscribed, homogeneously enhancing mass in the right paravertebral space, displacing the carotid sheath-radiologically consistent with a schwannoma. The tumor was excised via a transcervical approach and found intraoperatively to originate from the CSC. Histopathology confirmed a benign schwannoma. Postoperatively, the patient developed first-bite syndrome (FBS), managed conservatively with gradual symptom improvement. At 6-month follow-up, she remained asymptomatic with no evidence of recurrence.</p><p><strong>Conclusion: </strong>Parapharyngeal schwannomas are rare neurogenic tumors that often present with vague symptoms, delaying diagnosis. CSC schwannomas, though uncommon, carry a high risk of postoperative complications such as FBS and Horner's syndrome. Accurate imaging, early recognition, and multidisciplinary planning are essential for safe surgical resection and optimal patient outcomes. This case, alongside our literature review, emphasizes the importance of correlating tumor origin with clinical behavior and postoperative sequelae.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251361249"},"PeriodicalIF":0.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Hidden Effects of Vaping: A Study on Nasal Mucociliary Clearance.","authors":"Ahmet Koder, Yağmur Topçakar","doi":"10.1177/01455613251362043","DOIUrl":"https://doi.org/10.1177/01455613251362043","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the effect of e-cigarette use on nasal mucociliary clearance (NMC) by comparing e-cigarette users, traditional cigarette smokers, and nonsmokers. Although numerous studies have investigated the impact of cigarettes and other tobacco products on mucociliary clearance, research specifically focusing on e-cigarettes is limited.</p><p><strong>Methods: </strong>The study included 120 healthy participants, comprising 40 electronic cigarette users, 40 cigarette users, and 40 nonsmokers. NMC was evaluated using the saccharin test. Participants were asked to retain a saccharin particle on the inferior turbinate, and the time taken for the participant to perceive the sweet taste was recorded as the NMC time. The results were compared and analyzed statistically using the Statistical Package for the Social Sciences (SPSS).</p><p><strong>Results: </strong>The mean NMC time for e-cigarette users was 14.08 ± 5.99, which was significantly longer than that of nonsmokers, who had a mean NMC time of 10.80 ± 5.28 (<i>P</i> = .027), indicating impaired mucociliary clearance. The NMC time for cigarette smokers was 13.13 ± 6.97, which was also significantly prolonged compared to nonsmokers. No statistically significant difference was found between the groups regarding mean age.</p><p><strong>Conclusion: </strong>This study demonstrates that electronic cigarette use is associated with impairment of NMC, similar to conventional cigarette smoking. The findings suggest that e-cigarette use may have detrimental effects on the respiratory defense mechanism, potentially increasing the risk of respiratory infections and other pulmonary complications.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251362043"},"PeriodicalIF":0.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Martínez-Herrera et al Titled \"Quality of Life and Functionality of Head and Neck Cancer Patients Are Diminished as a Function of Sarcopenia and Obesity\".","authors":"Efsun Somay, Erkan Topkan, Ugur Selek","doi":"10.1177/01455613251360122","DOIUrl":"https://doi.org/10.1177/01455613251360122","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251360122"},"PeriodicalIF":0.0,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic and Therapeutic Challenges in Limited GPA With Nasal Synechiae: A Case Report and Literature Review.","authors":"Abdullah S AlDughaither, Abdulmohsin S Aldossari, Ali M Alsudays, Sultan Mogren Almogairen, Surayie H Al Dousary","doi":"10.1177/01455613251358076","DOIUrl":"https://doi.org/10.1177/01455613251358076","url":null,"abstract":"<p><strong>Background: </strong>Usually linked with anti-neutrophil cytoplasmic antibodies (ANCA), granulomatosis with polyangiitis (GPA) is an uncommon systemic necrotizing vasculitis. Although GPA sometimes shows multiorgan involvement, the confined phenotype-mostly affecting the upper respiratory tract-can provide major diagnostic and therapeutic difficulties. Though nonsystemic, limited GPA might resemble chronic rhinosinusitis and is at risk for progression or consequences.</p><p><strong>Case: </strong>Following COVID-19 immunization and past COVID-19 infection, we describe a case of a 23 year-old girl presenting with persistent nasal obstruction, headache, severe facial pain, crustation, nose bleeding, and anosmia for 1.5 years. Examination revealed bilateral nasal ulceration and crusting; evaluation also indicated mucosal thickening and positive c-ANCA with high proteinase 3 titers. Without granulomatous characteristics, histopathology revealed persistent inflammation and inflammatory nasal polyps. The patient was first managed with methotrexate; therapy was upgraded to rituximab (RTX) due to ongoing symptoms. After RTX induction, the patient achieved clinical remission, with resolution of nasal symptoms and normalization of inflammatory markers. She stayed in remission at the follow-up.</p><p><strong>Conclusion: </strong>This case highlights the diagnostic complexity and therapeutic challenges associated with limited GPA, particularly when ear, nose, and throat symptoms predominate without systemic involvement. Key to reaching remission is early rheumatologic referral, interdisciplinary treatment, and rapid escalation to biologic therapy. RTX is a good and well-tolerated choice in refractory restricted GPA; yet more studies are warranted.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251358076"},"PeriodicalIF":0.0,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retropharyngeal Ectopic Papillary Thyroid Carcinoma Coexisting with Orthotopic Goiter: A Rare Case Report.","authors":"Xiaxia Li, Guokang Fan, Zhewei Lou","doi":"10.1177/01455613251359427","DOIUrl":"https://doi.org/10.1177/01455613251359427","url":null,"abstract":"<p><strong>Objective: </strong>Ectopic thyroid carcinoma is rare. We present an exceptionally rare case of primary retropharyngeal ectopic papillary thyroid carcinoma (PTC) coexisting with an orthotopic thyroid goiter, aiming to enhance clinical awareness of this condition and to emphasize the importance of comprehensive management of both the ectopic lesion and the orthotopic thyroid.</p><p><strong>Methods: </strong>Case report and literature review.</p><p><strong>Results: </strong>A 29-year-old male with a 3-year history of pharyngeal foreign body sensation underwent laryngoscopy and noncontrast CT/MRI, revealing a 2.0 × 3.5 cm left retropharyngeal mass. The mass was confirmed as papillary carcinoma via transoral excision. Postoperative contrast-enhanced CT identified metastatic-level VI lymphadenopathy, prompting total thyroidectomy with central neck dissection. Histopathology verified ectopic PTC with central node metastasis (1/20 nodes). Orthotopic thyroid exhibited nodular goiter without malignancy. No recurrence was observed during 36 months of follow-up.</p><p><strong>Conclusions: </strong>This case highlights retropharyngeal ectopic PTC's diagnostic complexity in a patient with orthotopic thyroid gland. Management of ectopic thyroid carcinoma may be guided by thyroid carcinoma guidelines, given its rarity. Total thyroidectomy is recommended to exclude concurrent thyroid malignancy and enable thyroglobulin-based surveillance.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251359427"},"PeriodicalIF":0.0,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusually Huge Keloid Complicating a Unilateral Otoplasty.","authors":"Adel Azar, Ahmad Alkheder, Diana Mohammad, Ahmad Mustafa","doi":"10.1177/01455613251358656","DOIUrl":"https://doi.org/10.1177/01455613251358656","url":null,"abstract":"<p><p>Giant recurrent auricular keloids, particularly those complicated by donor-site involvement, present significant therapeutic challenges due to aggressive fibroblast biology and high recurrence rates. We report a complex case of a 15-year-old female who developed a massive recurrent auricular keloid with associated abdominal donor-site keloid following otoplasty and subsequent skin grafting. Initial otoplasty at age 10 was complicated by keloid formation, requiring excision and abdominal full-thickness grafting. By age 15, she presented with a recurrent auricular keloid causing auricular deformity, tragus distortion, and external auditory canal obstruction, alongside a donor-site keloid. Management involved the radical excision of both keloids. To minimize tension-induced recurrence, the auricular wound underwent deliberate secondary intention healing, while the abdominal site was closed primarily under minimal tension. Adjuvant therapy comprised 6 weekly intralesional interferon-gamma (IFN-γ) injections (1 million units auricle; 0.5 million units abdomen). This multimodal approach leveraged IFN-γ's antifibrotic properties, including ferroptosis induction in keloid fibroblasts. At 1-year follow-up, both sites exhibited sustained remission with good fibrosis and acceptable cosmesis without recurrence. This case demonstrates that tension-free excision with secondary intention healing, combined with intralesional IFN-γ, offers a promising strategy for managing complex pediatric keloids where conventional therapies carry substantial limitations. The protocol effectively addresses both biological recurrence drivers and psychosocial burdens inherent to disfiguring scars.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251358656"},"PeriodicalIF":0.0,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144677051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}