Deniz Hanci, Öykü İzel Onaran, Huseyin Altun, Yavuz Uyar
{"title":"The Tricellufuse Technique for Closing Nasal Septal Perforations.","authors":"Deniz Hanci, Öykü İzel Onaran, Huseyin Altun, Yavuz Uyar","doi":"10.1177/01455613241271700","DOIUrl":"https://doi.org/10.1177/01455613241271700","url":null,"abstract":"<p><p><b>Objective:</b> Nasal septal perforation (NSP) is a structural anomaly that affects the mucosa, cartilage, and bone of the nasal septum, often stemming from septoplasty as the primary cause. Spontaneous healing of a perforated septum is rare, and typically the healing process is observed until it is determined that the condition is stable and no longer deteriorating, at which point surgical intervention is considered. Numerous surgical techniques have been proposed for NSP repair. This study introduces a novel approach incorporating a fascia lata graft with fat tissue and diced septal cartilage to reconstruct medium-sized NSP. <b>Methods:</b> The researchers conducted a retrospective analysis involving 22 patients who underwent repair for NSP from January 2021 to January 2023. Grafts were obtained, and the perforation was addressed using an open rhinoplasty technique, followed by the insertion and suturing of the graft. <b>Results:</b> The mean size of the septal perforations was 12 mm horizontally and 13 mm vertically. All patients with NSPs were chosen as medium size (within 0.5-2 cm). The mean follow-up period was 12 months. Complete closure of NSP was achieved in 19 out of 22 patients (86.3%). Among the cases, 15 were male (68%), and the ages ranged from 25 to 45 years with a mean of 35. Eight cases (36%) were smokers. After 12 months postoperatively, closure was not achieved in 3 medium-sized NSPs due to smoking. . The analysis revealed that the failure rate in the smoker group was statistically significant (<i>P</i> = .036). <b>Conclusion:</b> The TriCelluFuse technique, combining fascia lata, fat tissue, and diced septal cartilage, is a secure and reliable method for closing NSPs. It has a significant success rate and should be considered a viable option for individuals with NSPs.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bunyamin Kutlu, Selcuk Arslan, Bengu Cobanoglu, Mehmet Imamoglu, Abdulcemal Isik, Osman Bahadir
{"title":"Retrospective Analysis of Systemic Steroid and Combined Systemic-Intratympanic Steroid Treatment Results and Prognostic Factors in Sudden Idiopathic Hearing Loss.","authors":"Bunyamin Kutlu, Selcuk Arslan, Bengu Cobanoglu, Mehmet Imamoglu, Abdulcemal Isik, Osman Bahadir","doi":"10.1177/01455613241275343","DOIUrl":"https://doi.org/10.1177/01455613241275343","url":null,"abstract":"<p><p>Sudden idiopathic hearing loss (SIHL) is defined as sensorineural hearing loss at 30 dB or more at 3 consecutive frequencies that begins within 72 hours, and the etiology of the disease is still unclear. Steroid treatment is used as systemic and local (intratympanic) in sudden hearing loss, and different results have been reported for both treatment modalities. This study aimed to compare the results of the treatment in patients who received systemic steroid (SS) therapy and in patients who received systemic and intratympanic steroid (ITS) therapy for SIHL. In all, 169 patients who were admitted to our clinic with the diagnosis of SIHL between January 2007 and June 2018 were randomly divided into 2 treatment groups according to their admittance day, such as patients who received only SSs and patients who received SSs and ITSs. The results of these 2 treatment protocols were investigated. Statistical analysis was performed for all patients by grouping many factors that could be effective in prognosis, such as age, sex, and time of initiation of treatment. No differences were found between the SS group and the combined systemic-ITS group in treatment success. It was determined that being under 15 years of age, over 60 years of age, starting treatment after 7 days, vertigo, high initial hearing loss, descendant type, and total loss type in the audiogram configuration are poor prognostic factors. Being between 16 and 59 years of age, starting treatment within 7 days, having no vertigo, mild hearing loss, and having ascendant and plateau type in audiogram configuration are good prognostic factors. We observed that adding ITS treatment to SS treatment as an initial treatment did not provide any extra benefit. However, prospective, randomized, controlled studies will clarify the topic.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ming Xiong, Jia-Wei Luo, Jia Ren, Juan-Juan Hu, Lan Lan, Ying Zhang, Dan Lv, Xiao-Bo Zhou, Hui Yang
{"title":"Applying Deep Learning with Convolutional Neural Networks to Laryngoscopic Imaging for Automated Segmentation and Classification of Vocal Cord Leukoplakia.","authors":"Ming Xiong, Jia-Wei Luo, Jia Ren, Juan-Juan Hu, Lan Lan, Ying Zhang, Dan Lv, Xiao-Bo Zhou, Hui Yang","doi":"10.1177/01455613241275341","DOIUrl":"https://doi.org/10.1177/01455613241275341","url":null,"abstract":"<p><p><b>Objectives:</b> Vocal cord leukoplakia is clinically described as a white plaque or patch on the vocal cords observed during macroscopic examination, which does not take into account histological features or prognosis. A clinical challenge in managing vocal cord leukoplakia is to assess the potential malignant transformation of the lesion. This study aims to investigate the potential of deep learning (DL) for the simultaneous segmentation and classification of vocal cord leukoplakia using narrow band imaging (NBI) and white light imaging (WLI). The primary objective is to assess the model's accuracy in detecting and classifying lesions, comparing its performance in WLI and NBI. <b>Methods:</b> We applied DL to segment and classify NBI and WLI of vocal cord leukoplakia, and used pathological diagnosis as the gold standard. <b>Results:</b> The DL model autonomously detected lesions with an average intersection-over-union (IoU) >70%. In classification tasks, the model differentiated between lesions in the surgical group with a sensitivity of 93% and a specificity of 94% for WLI, and a sensitivity of 99% and a specificity of 97% for NBI. In addition, the model achieved a mean average precision of 81% in WLI and 92% in NBI, with an IoU threshold >0.5. <b>Conclusions:</b> The model proposed by us is helpful in assisting in accurate diagnosis of vocal cord leukoplakia from NBI and WLI.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anciya P Pinto, Dhanshree R Gunjawate, Ramiz Malik, Rohit Ravi, Kaushlendra Kumar
{"title":"Vestibular-Evoked Myogenic Potential in Otosclerosis: A Systematic Review.","authors":"Anciya P Pinto, Dhanshree R Gunjawate, Ramiz Malik, Rohit Ravi, Kaushlendra Kumar","doi":"10.1177/01455613241278754","DOIUrl":"https://doi.org/10.1177/01455613241278754","url":null,"abstract":"<p><p><b>Background:</b> Vestibular symptoms are noted in about 40% of the individuals with otosclerosis. Vestibular-evoked myogenic potential (VEMP) is a short latency potential that assesses the functioning of otolithic organs in the vestibular system. <b>Aim/Objectives:</b> This systematic review explored the VEMP findings in individuals with otosclerosis. <b>Material and Methods:</b> Three databases, PubMed, Scopus, and Cochrane were used to perform a systematic literature review regarding VEMP findings among individuals with otosclerosis. <b>Results:</b> A total of 14 studies that encompasses various VEMP parameters in otosclerosis patients were included. The air-conducted vestibular-evoked myogenic potential (AC-VEMP) often had poor response rates in otosclerosis due to conductive hearing loss. Presence of bone-conducted vestibular-evoked myogenic potential (BC-VEMP) before surgery indicated intact otolithic organs in otosclerosis. Postoperatively, presence of VEMP indicated intact vestibular structures postsurgery, while its absence could indicate vestibular trauma, though other factors like stimulus intensity or efficacy of the fitted piston could influence the results. AC-VEMP responses postsurgery suggested resolution of conductive pathology or absence of lasting effects of otosclerosis. Studies show cVEMP is more affected, indicating saccular dysfunction. <b>Conclusion:</b> Otosclerosis affects VEMP responses, with variations observed between AC- and BC-VEMPs. While AC-VEMP responses may be affected by conductive hearing loss, BC-VEMPs offer insights into inner ear function.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dejuan Wang, Zheng Jiang, Lixiao Fan, Xin Yang, Pengwei Zhao, Fei Chen, Jun Liu
{"title":"A Modified Epiglottis-Tongue Root Flap for Postoperative Laryngeal Stenosis in a Cancer Patient with a History of Radiotherapy.","authors":"Dejuan Wang, Zheng Jiang, Lixiao Fan, Xin Yang, Pengwei Zhao, Fei Chen, Jun Liu","doi":"10.1177/01455613241281604","DOIUrl":"https://doi.org/10.1177/01455613241281604","url":null,"abstract":"<p><p><b>Introduction:</b> Cricohyoidoepiglottopexy (CHEP) has emerged as a promising surgical technique for treating laryngeal stenosis, offering a low rate of restenosis and a high rate of successful decannulation. However, postoperative radiation therapy can complicate open surgery for some patients due to radiation-induced cellular and tissue damage. This damage can make adequate exposure or mobilization of the larynx challenging. <b>Case Summary:</b> A 71-year-old male, who had undergone a partial laryngectomy 3 years prior, developed laryngeal stenosis and difficulty plugging after 35 rounds of radiotherapy. Initially, CHEP was planned, but intraoperatively, it was found that traditional CHEP would result in excessive anastomotic tension. To prevent complications, we designed an epiglottis-tongue root flap for laryngeal function reconstruction. The patient experienced no restenosis and was successfully extubated. <b>Discussion:</b> By separating the preepiglottal space and mobilizing the base of the tongue to construct the epiglottis-tongue root flap, modified CHEP can achieve laryngeal function reconstruction in patients postradiotherapy. It is essential to conduct a comprehensive evaluation of the patient's overall condition, degree of stenosis, tongue-to-tongue root status, and cervical tissue adhesion before surgery.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Ansari, Cheyenne Rahimi, Jagan D Gupta, Neel D Gupta, Triet M Do, Enrique Palacios
{"title":"Bezold's Abscess in a Middle-Aged Man.","authors":"Mohammed Ansari, Cheyenne Rahimi, Jagan D Gupta, Neel D Gupta, Triet M Do, Enrique Palacios","doi":"10.1177/01455613241282907","DOIUrl":"https://doi.org/10.1177/01455613241282907","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesca Pirola, Francesco Giombi, Gian Marco Pace, Michele Cerasuolo, Jessica Zuppardo, Martina Sebastiani, Gianmarco Giunta, Giuseppe Mercante, Giuseppe Spriano, Luca Malvezzi
{"title":"Non-Mucosa Sparing (Reboot) Surgery as a Possible Rescue Therapy in Patients Locally Unresponsive to Biologics.","authors":"Francesca Pirola, Francesco Giombi, Gian Marco Pace, Michele Cerasuolo, Jessica Zuppardo, Martina Sebastiani, Gianmarco Giunta, Giuseppe Mercante, Giuseppe Spriano, Luca Malvezzi","doi":"10.1177/01455613241282566","DOIUrl":"https://doi.org/10.1177/01455613241282566","url":null,"abstract":"<p><p><b>Objective:</b> Evaluation of effectiveness of non-mucosa-sparing (eg, reboot) surgery in patients with chronic rhinosinusitis with nasal polyps (CRSwNP), poorly responders to mAb therapy, who failed repeated comprehensive endoscopic surgeries. <b>Methods:</b> Retrospective observational study. Patients who were under mAb for a comorbid condition but still had no control over their CRSwNP were included. Data collected were preoperative tissue eosinophilia, nasal polyp score (NPS), 22-item sinonasal outcome test (SNOT-22), visual analog scale (VAS) for nasal symptoms, Lund-Kennedy score for nasal crusts (LK-c) and synechiae (LK-s), and Lund-Mackay score (LMS). The same data were also collected postoperatively (at 12 months), besides LMS, and compared. <b>Results:</b> Overall, 20 patients were included. Pre-reboot scores were: NPS = 4.95 ± 1.70; SNOT-22 = 63.90 ± 19.15; VAS-global = 7.06 ± 1.50; LM = 19.0 ± 4.01; LK-c = 1.10 ± 0.64; and LK-s = 1.30 ± 0.73. Tissue biopsies revealed a high density of eosinophils in all cases, ≥10/HPF (range 10-60). Mean postoperative outcomes were: NPS = 0; SNOT-22 = 17.90 ± 6.80; VAS-global = 1.91 ± 1.17; LK-c = 1.45 ± 0.51; and LK-s = 1.50 ± 0.61. The difference of mean pre- and postoperative scores was significant for both NPS, SNOT-22 and VAS-global (<i>P</i> < .001). No differences were observed for LK-c and LK-s (<i>P</i> > .05). Nasal specimens showed markedly reduced tissue eosinophils (100% of cases). <b>Conclusion:</b> Reboot sinus surgery might be an effective solution for recalcitrant CRSwNP patients unresponsive to mAbs and multiple sinus surgeries.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sirine Ayadi, Ons Kharrat, Dhouha Ben Salah, Youssef Hbaieb, Souha Kallel, Melek Mnejja, Nabila Rekik, Ilhem Charfeddine
{"title":"Parathyroid Carcinomas: A Series of 6 Cases and Literature Review.","authors":"Sirine Ayadi, Ons Kharrat, Dhouha Ben Salah, Youssef Hbaieb, Souha Kallel, Melek Mnejja, Nabila Rekik, Ilhem Charfeddine","doi":"10.1177/01455613241282473","DOIUrl":"https://doi.org/10.1177/01455613241282473","url":null,"abstract":"<p><p>Parathyroid carcinoma (PC) is a rare endocrine malignancy. We report 6 cases of PCs operated on in our department, during a period of 12 years (2010-2021). All of our patients presented severe hyperparathyroidism, high calcium levels, and very elevated parathormone (PTH) rates. Five were between the fifth and sixth decades of life and 1 patient was 37 years old. The parathyroid gland was only palpable in 1 case. All of our patients underwent cervical ultrasound and 5 of them underwent 99m Tc-MIBI scintigraphy. One of the patients presented bilateral parathyroid masses. All our patients were treated surgically: a parathyroidectomy was performed in all cases. In 1 patient, parathyroidectomy was performed in conjunction with a homolateral loboisthmectomy, as the diagnosis of PC was suspected preoperatively due to pulmonary metastases. The final anatomopathological study revealed PC in all cases. Follow-up was uneventful in 5 cases and 1 patient was lost to follow-up. Clinicians should suspect PC in patients with severe hypercalcemia, extremely elevated PTH levels, large parathyroid lesions, and distant metastases. Complete surgical resection, extended to the homolateral thyroid lobe, remains the recommended treatment.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthias Balk, Atina Rak, Robin Rupp, Matti Sievert, Sarina Müller, Michael Koch, Heinrich Iro, Magdalena Gostian, Florian Putz, Thomas Weißmann, Moritz Allner, Antoniu-Oreste Gostian
{"title":"Impact of Cancer Localization on Symptom Burden and Quality of Life in Head and Neck Cancers: A Comparative Study","authors":"Matthias Balk, Atina Rak, Robin Rupp, Matti Sievert, Sarina Müller, Michael Koch, Heinrich Iro, Magdalena Gostian, Florian Putz, Thomas Weißmann, Moritz Allner, Antoniu-Oreste Gostian","doi":"10.1177/01455613241274025","DOIUrl":"https://doi.org/10.1177/01455613241274025","url":null,"abstract":"Background: Head and neck cancer (HNC) is a critical concern in oncology, with notable disparities in survival rates. While the long-term symptom burden in HNC survivors and its impact on quality of life (QoL) has been explored, there is limited understanding of the influence of cancer localizations on these aspects. This study aims to elucidate the role of cancer localizations in shaping long-term outcomes in HNC patients. Methods: A cross-sectional study was conducted at the University Hospital Erlangen’s Department of Otolaryngology, exploring the impact of cancer localization on symptom burden and QoL in 138 HNC patients using the University of Washington Quality of Life Questionnaire Version 4. Results: In our study of HNC patients, we investigated symptom burden across different cancer localizations, including oral cavity, oropharyngeal, hypopharyngeal, laryngeal, and cancer of unknown primary (CUP). While we found no significant variations in parameters such as pain, appearance, and activity, notable differences emerged in swallowing, speech, and salivation. Patients with oral cavity and laryngeal carcinomas had significantly higher swallowing and salivation scores compared to those with oropharyngeal carcinoma and CUP, while speech-related symptoms were lower for oral cavity and laryngeal carcinoma patients. Importantly, these symptom differences did not significantly impact health-related and overall QoL. These findings emphasize the nuanced interplay between symptomatology and QoL in different HNC cancer localizations. Conclusion: The research highlights significant disparities in post-treatment symptoms across different HNC localizations and underscores the need for personalized treatment and management strategies to address unique challenges associated with each HNC type, ultimately aiming to enhance post-treatment QoL.","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142251224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}