Ear, nose, & throat journal最新文献

{"title":"Clinical Study of Early-Nasal Intervention Among Individuals With Nasopharyngeal Cancer to Prevent Radiation-Induced Sinusitis.","authors":"Tianbin Ouyang, Hou Shi, Yaowen Wang, Jianliang Zhou","doi":"10.1177/01455613251347164","DOIUrl":"https://doi.org/10.1177/01455613251347164","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to explore the impact of early-nasal intervention on sinusitis caused by radiation therapy in patients with nasopharyngeal carcinoma (NPC), in order to prevent and reduce the occurrence of radiation-induced sinusitis.</p><p><strong>Methods: </strong>Patients with NPC who were scheduled for intensity-modulated radiation therapy were randomized into an experimental group (n = 40) and a control group (n = 40) with concealed allocation. While the control group received only compound menthol drops, the experimental group received nasal treatments (nasal saline irrigation, corticosteroid nasal spray, and compound menthol drops) during radiation therapy and for 6 months after therapy. Sinusitis-related scores (symptoms scores, nasal endoscopy scores, and MRI findings) and mucociliary transport rate (MTR, mm/min) were collected at different time points of radiation therapy.</p><p><strong>Results: </strong>Before radiation therapy, there were no statistically-significant differences between the 2 groups in terms of sinusitis-related scores, MTR and general conditions (<i>P</i> > .05). Both experimental and control groups showed statistically-significant differences in sinusitis-related scores between time points after radiation therapy (<i>P</i> < .01), sinusitis-related scores peaked at 6 months after radiation therapy, and there were also significant differences in the MTR between time points during radiation therapy (<i>P</i> < .01). Sinusitis-related scores differed significantly between the 2 groups after the completion of radiation therapy and at the 3rd, 6th, and 12th month after radiation therapy (<i>P</i> < .05). At the 3rd and 6th month after radiation therapy, there was a statistically-significant difference in the nasal MTR between the 2 groups (<i>P</i> < .05).</p><p><strong>Conclusions: </strong>The experimental group and the control group showed statistically-significant changes in sinusitis symptoms scores, endoscopic findings, and MRI findings at multiple important time points after radiation therapy. This type of intervention demonstrates significant clinical value and safety.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251347164"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Study on Early-Auditory Development in Children Who Have Slightly-Asymmetric Hearing Loss and Are Wearing Hearing Aids.","authors":"Xiao-Yun Zhang, Wei-Li Kong, Ning-Ying Song","doi":"10.1177/01455613251345683","DOIUrl":"https://doi.org/10.1177/01455613251345683","url":null,"abstract":"<p><strong>Objectives: </strong>There have been few studies on slightly-asymmetric sensorineural hearing loss (SASHL), and no study to date has reported on the longitudinal development of early-auditory ability in children with SASHL and wearing hearing aids (HAs). Thus, we explored the developmental trajectory of early-auditory ability of children with SASHL who wear HAs, and compared the differences in different types of SASHL (the mild-moderate, moderate-severe, and severe-profound).</p><p><strong>Methods: </strong>We performed a prospective, longitudinal study of 31 children with SASHL who were followed for 18 months. Their early-prelingual auditory development (EPLAD) was evaluated using the Infant-Toddler: Meaningful Auditory Integration Scale (ITMAIS), before wearing HAs and at the 1st, 3rd, 6th, 12th, and 18th month after implementing HAs. A spline function was implemented to describe the observed EPLAD trajectory. A cubic polynomial regression model was used to predict the change in the ITMAIS score over time, and nonparametric tests or the chi-squared test was used to compare differences between groups.</p><p><strong>Results: </strong>ITMAIS scores were statistically-significantly different between all subsequent follow-ups (<i>P</i> < 0.001). We constructed a highly-accurate predictive score of ITMAIS over time (<i>r</i>² = 0.99) and show that sound detection was always faster than sound recognition. The EPLAD score of the severe-profound group was always lower than those of the moderate-severe group and the severe-profound group (<i>P</i> < 0.05).</p><p><strong>Conclusions: </strong>The EPLAD trajectory of the SASHL children was steepest during the first month after HA fitting and leveled-off gradually thereafter. The more severe the degree of hearing loss, the slower the EPLAD rate, which emphasizes the importance of early intervention. We recommend further longitudinal studies to elucidate the dynamics of the process and individual differences in early-childhood hearing ability.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251345683"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Safety and Efficacy of a Bioabsorbable Implant for Correction of Cartilaginous Septal Deviation.","authors":"Steven E Davis, Greg E Davis","doi":"10.1177/01455613251346589","DOIUrl":"https://doi.org/10.1177/01455613251346589","url":null,"abstract":"<p><strong>Introduction: </strong>Nasal septal deviation (NSD) is a leading cause of nasal airway obstruction, a condition that adversely affects quality of life. Septoplasty, typically performed with inferior turbinate reduction (ITR), is a common treatment to correct NSD.</p><p><strong>Methods: </strong>We conducted a prospective feasibility study of a novel, minimally-invasive implant (SeptAlign^TM) to correct cartilaginous NSD as an alternative to traditional open septoplasty. The implant was inserted either in the operating room or at the medical office. ITR was performed in conjunction with the implant procedure.</p><p><strong>Results: </strong>We present 12 month results for 14 participants with mobile cartilaginous NSD. The procedure and implant were well-tolerated. At the 12th month post-procedure, the median Nasal Obstruction Symptom Evaluation (NOSE) score improved 71.8% from baseline (58-15; <i>P</i> = .001) and the median Sino-Nasal Outcome Test-22 (SNOT-22) score improved 60.3% from baseline score (37-8; <i>P</i> = .004). Most of the improvement in symptoms occurred within the first month following the procedure at which point 92.9% and 78.6% of participants were considered NOSE and SNOT-22 responders, respectively.</p><p><strong>Conclusion: </strong>These initial findings support the safety, tolerability, and early efficacy of the SeptAlign^TM implant with concomitant ITR and suggest that the implant procedure can be safely performed in a medical office setting. Based on these promising initial data, larger, randomized, controlled studies should be conducted.</p><p><strong>Clinicaltrials: </strong>gov:NCT05967169; https://clinicaltrials.gov/study/NCT05967169?term=Spirair&rank=2.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251346589"},"PeriodicalIF":0.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144228048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tracheal Hirudiniasis: A Case Report.","authors":"Shivam Pandey, Shravya Singh Karki, Sangita Bhandary, Suban Bhandari, Girban Pandey","doi":"10.1177/01455613251345419","DOIUrl":"https://doi.org/10.1177/01455613251345419","url":null,"abstract":"<p><strong>Introduction: </strong>Leeches are freshwater ectoparasites that inhabit streams, pools, and springs. Internal infestation occurs by ingestion of contaminated water or direct exposure while swimming. This report presents a rare case of tracheal hirudiniasis.</p><p><strong>Case description: </strong>A 34 year-old Nepalese woman presented with 1 week history of throat discomfort and dysphagia after the ingestion of river water. The initial clinical and endoscopic evaluations were unremarkable. Twelve hours after admission, a leech was visualized at the base of the tongue, but multiple failed extraction attempts led to its migration. Subsequently, rigid bronchoscopy under general anesthesia identified a leech in the trachea, 2 cm proximal to the carina. The parasite was successfully extracted with rigid bronchoscopy under general anesthesia, and the patient had a smooth recovery.</p><p><strong>Discussion: </strong>Internal hirudiniasis affects primarily the nasal cavity, oral cavity, pharynx, larynx, tracheobronchial tree, and esophagus, with rare cases in the abdomen, vagina, and eye. Symptoms depend on the site of infestation. Nasal cases present with epistaxis and obstruction, while tracheobronchial involvement may cause cough, dyspnea, and hemoptysis. Removal is challenging due to the mucosal attachment of the leech and its slippery nature. Various detachment techniques, including anesthetics, cryoprobes, and hypertonic solutions, have been described in the literature. In this case, general anesthesia likely facilitated detachment, enabling a successful extraction.</p><p><strong>Conclusions: </strong>Internal hirudiniasis should be considered in patients with freshwater exposure with relevant symptoms. Prompt recognition and appropriate extraction techniques are essential to prevent complications. Increased awareness among health care workers and the general population is essential for early diagnosis, prevention, and effective management.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251345419"},"PeriodicalIF":0.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144228049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A \"Don't Touch\" Lesion: Arrested Pneumatization of the Sphenoid Mimicking Chordoma.","authors":"Gökhan Polat, Fatma Atılgan, Esin Aslı Aybayar","doi":"10.1177/01455613251345346","DOIUrl":"https://doi.org/10.1177/01455613251345346","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251345346"},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cervical Thymopharyngeal Duct Cyst Mimicking a Thyroid Nodule in an Adult: A Rare Case Report.","authors":"Jihène Houas, Mouna Belakhdher, Ghada Grassi, Taghrid Tlili, Monia Ghammam","doi":"10.1177/01455613251343728","DOIUrl":"https://doi.org/10.1177/01455613251343728","url":null,"abstract":"<p><p>Thymopharyngeal duct cysts are rare congenital lesions resulting from the persistence of the embryonic thymopharyngeal tract, typically presenting in pediatric populations. Adult cases are exceedingly uncommon and often misdiagnosed due to their rarity and nonspecific clinical features. We report the case of a 34-year-old woman who presented with a slowly-enlarging, painless left cervical mass initially suggestive of a thyroid pathology. Imaging revealed a well-defined cystic lesion at the lower pole of the thyroid gland. Surgical excision via a low cervicotomy was performed, and a left lobo-isthmectomy was carried out due to the lesion's adherence to the thyroid. Final histopathological analysis confirmed a thymopharyngeal duct cyst. This case underscores the diagnostic challenges of lateral neck cysts in adults and highlights the importance of considering rare embryologic anomalies in the differential diagnosis, particularly when lesions mimic more common thyroid or branchial cleft pathologies.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251343728"},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gene Therapy for Congenital Hearing Loss: Are You Ready to Anticipate the Genetic Tests?","authors":"Andrea Migliorelli, Andrea Ciorba","doi":"10.1177/01455613251346613","DOIUrl":"https://doi.org/10.1177/01455613251346613","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251346613"},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomical Location as a Predictor of Treatment Response in Globus Pharyngeus.","authors":"Sang-Hyun Lee, Hong Kyu Lee, Mi Jung Kwon, Heejin Kim, Jeong Wook Kang","doi":"10.1177/01455613251336895","DOIUrl":"https://doi.org/10.1177/01455613251336895","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate whether the anatomical location of the globus sensation influences treatment outcome in patients with globus pharyngeus.</p><p><strong>Methods: </strong>A prospective cohort study was conducted between March 2023 and May 2024 with 55 patients who presented with globus sensation. The participants were categorized into the upper and lower globus groups based on the anatomical location of globus sensation relative to the upper esophageal sphincter. All patients received proton pump inhibitor (PPI) therapy for up to 12 weeks, and treatment response was assessed using the Reflux Symptom Index (RSI) and Reflux Finding Score (RFS). Log-rank tests and logistic regression analysis were performed to identify the factors associated with treatment response.</p><p><strong>Results: </strong>Patients with upper globus showed a significantly-higher rate of symptom improvement (78.6%) than those with lower globus (40.7%). Symptom severity (measured by the RSI) was higher in the lower globus group, while posterior commissure hypertrophy (measured by the RFS) was more prevalent in the upper globus group. Factors positively associated with symptom improvement included the location of the upper globus and coffee cessation. The lower globus group showed resistance to PPI therapy.</p><p><strong>Conclusion: </strong>Patients with upper globus respond better to PPI therapy, whereas those with lower globus do not. The anatomical location of the globus sensation may affect treatment outcomes.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251336895"},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence-Assisted Diagnosis of an Unusual Cause of Periodic Epistaxis: A Case Report.","authors":"Jérôme R Lechien, Sarah Saxena, Luigi A Vaira, Stephane Hans, Antonino Maniaci","doi":"10.1177/01455613251335385","DOIUrl":"https://doi.org/10.1177/01455613251335385","url":null,"abstract":"<p><p>Epistaxis is a common cause of consultation in otolaryngology, manifesting either as isolated episodes or recurrent events. In this paper, we report the history of an 8-year-old African male who presented with periodic epistaxis temporally associated with joint inflammation. The diagnostic work-up, supported by artificial intelligence-based clinical decision support, led to the diagnosis of rheumatic fever. This case describes a very rare etiology of periodic epistaxis and demonstrates the potential usefulness of artificial intelligence as an adjunctive clinical tool. To our knowledge, this is the first reported case of rheumatic fever presenting with periodic epistaxis in the pediatric population.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251335385"},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Patient-Specific Factors to Differentiate Between Branchial Cleft Cysts and CUP Syndrome: A 10 Year Unicenter Study\".","authors":"Renu Sah, Ankita Mathur","doi":"10.1177/01455613251346604","DOIUrl":"https://doi.org/10.1177/01455613251346604","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251346604"},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}