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Prevalence of and Predictive Factors for Hypothyroidism Following Hemithyroidectomy. 甲状腺切除术后甲状腺功能减退的患病率及预测因素。
Ear, nose, & throat journal Pub Date : 2025-04-10 DOI: 10.1177/01455613251333190
Fadwa Cherni, Makram Tbini, Ines Riahi, Sarra Idriss, Rihab Laamouri, Mamia Ben Salah
{"title":"Prevalence of and Predictive Factors for Hypothyroidism Following Hemithyroidectomy.","authors":"Fadwa Cherni, Makram Tbini, Ines Riahi, Sarra Idriss, Rihab Laamouri, Mamia Ben Salah","doi":"10.1177/01455613251333190","DOIUrl":"https://doi.org/10.1177/01455613251333190","url":null,"abstract":"<p><strong>Purpose: </strong>Hemithyroidectomy is an appropriate procedure that is recommended for a number of thyroid conditions to preserve the functional contralateral thyroid lobe, but patients who underwent a hemithyroidectomy still run the risk of developing hypothyroidism. This study aimed to determine the incidence of hypothyroidism following a hemithyroidectomy as well as predictive risk factors.</p><p><strong>Methods: </strong>A retrospective analysis was carried out on all patients who underwent hemithyroidectomy between 2016 and 2022. Age, gender, preoperative and postoperative thyroid stimulating hormone (TSH) and free thyroxin (FT4), side, and volume of the remaining lobe, as well as the histologic diagnosis, were all examined in the patients. To identify the predictors of hypothyroidism, statistical analyses, both univariate and multivariate, were conducted.</p><p><strong>Results: </strong>Out of 224 patients, 18.25% had hypothyroidism following surgery. This complication appeared within the first year in 88% of the cases. Patients with thyroiditis (<i>P</i> = .036), preoperative TSH levels greater than 1.72 mIU/L (<i>P</i> < .001), right side hemithyroidectomy (<i>P</i> = .017), and residual lobe volume less than 3.57 cm (<i>P</i> < .001) had a significantly higher risk of developing hypothyroidism.</p><p><strong>Conclusion: </strong>After hemithyroidectomy, hypothyroidism is a major complication that should be carefully evaluated preoperatively based on risk factors of hypothyroidism. Furthermore, our results confirm the need for routine serum TSH monitoring for a minimum of 1 year following hemithyroidectomy.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251333190"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Head and Neck Extramedullar Plasmacytoma. 头颈部髓外浆细胞瘤。
Ear, nose, & throat journal Pub Date : 2025-04-10 DOI: 10.1177/01455613251333189
İmdat Yüce, Nezaket Tektaş, Mete Gündoğ, Özlem Canöz, Mehmet Can Kaya, Sedat Çağlı
{"title":"Head and Neck Extramedullar Plasmacytoma.","authors":"İmdat Yüce, Nezaket Tektaş, Mete Gündoğ, Özlem Canöz, Mehmet Can Kaya, Sedat Çağlı","doi":"10.1177/01455613251333189","DOIUrl":"https://doi.org/10.1177/01455613251333189","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to contribute to the literature by sharing experience of head-neck extramedullary plasmacytoma (EMP), which are rarely seen.</p><p><strong>Methods: </strong>A total of 11 patients treated for head and neck region EMP between 2000 and 2023 were screened retrospectively.</p><p><strong>Results: </strong>The 11 patients comprised 9 men and 2 women with a mean age of 55.1 ± 16.2 (range, 16-74) years. The most affected regions were seen to be the sinonasal tract, larynx, and tonsils. In the histopathological examination, plasma cells had a mature or anaplastic appearance, and one of the kappa and lambda light chains was positive and the other was completely negative. The serum electrophoresis and bone marrow flow cytometry results were negative. Of the patients with confirmed EMP diagnosis, 8 were treated with radiotherapy (RT) alone, 1 patient with maxillectomy, and 1 patient endoscopic sinus surgery followed by RT. RT was applied at a dose of 44 to 50 Gy for 22 to 25 sessions. In 1 patient, RT and chemotherapy were applied together.</p><p><strong>Conclusion: </strong>In cases presenting with a submucosal, destructive tumor in the head and neck region, especially in the sinonasal region, EMP should be kept in mind. When histopathological results are confirmed, a differential diagnosis from multiple myeloma (MM) is required. Flow cytometry is of guidance in the differentiation of EMP from extranodal lymphoma. However, it should be noted that the effect of RT may be less in EMPs originating from the paranasal sinus compared with other anatomic regions, and surgery may be required before or after RT. A radiation dose of 45 Gy is sufficient for local control. Patients require long-term follow-up, as there is a possibility of EMP transforming to MM.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251333189"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of PENTOCLO Therapy in Treating Head & Neck Osteoradionecrosis: A Systematic Review. PENTOCLO治疗头颈部骨放射性坏死的疗效:系统评价。
Ear, nose, & throat journal Pub Date : 2025-04-10 DOI: 10.1177/01455613251331702
Arianna V Ramirez, Janisah Amirah I Saripada, Amy Wang, Viran J Ranasinghe, Orly M Coblens, Sepehr Shabani
{"title":"Efficacy of PENTOCLO Therapy in Treating Head & Neck Osteoradionecrosis: A Systematic Review.","authors":"Arianna V Ramirez, Janisah Amirah I Saripada, Amy Wang, Viran J Ranasinghe, Orly M Coblens, Sepehr Shabani","doi":"10.1177/01455613251331702","DOIUrl":"https://doi.org/10.1177/01455613251331702","url":null,"abstract":"<p><strong>Importance: </strong>Osteoradionecrosis (ORN) has been shown to affect up to 20% of all head and neck cancer patients receiving radiation therapy. Despite its prevalence, a standard definitive therapy to treat this condition has yet to be available. A novel treatment modality with pentoxifylline, tocopherol, and clodronate (PENTOCLO) was first reported in the literature in 2005. There has since been a steady rise in the number of studies exploring the efficacy of PENTOCLO in treating ORN in head and neck patients.</p><p><strong>Objective: </strong>This article investigates the efficacy of PENTOCLO in treating ORN in head and neck cancer patients.</p><p><strong>Evidence review: </strong>PubMed, Scopus, Cochrane Library, and Medline were used to review articles on PENTOCLO use for head and neck ORN from 2005 to the present. Two reviewers independently screened titles and abstracts from 114 articles, and inclusion was based on pair consensus. The main inclusion criteria were human clinical studies using PENTOCLO for at least 6 months in treating ORN in head and neck cancer patients. The selected main outcomes to determine the efficacy of PENTOCLO therapy were wound healing status after treatment, reduction in the percentage of exposed bone, and symptom surveys post-PENTOCLO therapy. Eight studies were selected for final statistical analysis.</p><p><strong>Findings: </strong>The primary site of ORN in most studies was mandible (77%). Of the 141 patients encompassed in this review, 66 (46.8%) patients had complete resolution, and 61 (43.3%) patients had significant wound healing. Total wound healing was achieved on an average of 10 months. The mean area of exposed bone decreased by 96% and the symptom survey scores decreased by 93% after treatment.</p><p><strong>Conclusion and relevance: </strong>These results suggest PENTOCLO may be an effective treatment option in patients with head and neck ORN.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251331702"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Eagle's Grip: A Rare Cause of Facial Nerve Paralysis. 鹰的抓握:面神经麻痹的罕见原因。
Ear, nose, & throat journal Pub Date : 2025-04-10 DOI: 10.1177/01455613251331865
Catherine F Roy, Jumanah Ardawi, Tamara Mijovic
{"title":"The Eagle's Grip: A Rare Cause of Facial Nerve Paralysis.","authors":"Catherine F Roy, Jumanah Ardawi, Tamara Mijovic","doi":"10.1177/01455613251331865","DOIUrl":"https://doi.org/10.1177/01455613251331865","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251331865"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple Congenital Cholesteatoma: The Risk of Missing the Other One. 多发性先天性胆脂瘤:错过另一个的风险。
Ear, nose, & throat journal Pub Date : 2025-04-10 DOI: 10.1177/01455613251331868
Ha-Nee Kwon, Sung-Won Choi, Se-Joon Oh
{"title":"Multiple Congenital Cholesteatoma: The Risk of Missing the Other One.","authors":"Ha-Nee Kwon, Sung-Won Choi, Se-Joon Oh","doi":"10.1177/01455613251331868","DOIUrl":"https://doi.org/10.1177/01455613251331868","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251331868"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reevaluating the Routine Use of Mastoid Pressure Dressings in Otologic Surgery: A Randomized Controlled Trial. 重新评估乳突压力敷料在耳科手术中的常规使用:一项随机对照试验。
Ear, nose, & throat journal Pub Date : 2025-04-10 DOI: 10.1177/01455613251333644
Alper Tabaru, Ozgur Yigit, Salih Akyel, Zeliha Kapusuz Gencer, Iskender Bayram
{"title":"Reevaluating the Routine Use of Mastoid Pressure Dressings in Otologic Surgery: A Randomized Controlled Trial.","authors":"Alper Tabaru, Ozgur Yigit, Salih Akyel, Zeliha Kapusuz Gencer, Iskender Bayram","doi":"10.1177/01455613251333644","DOIUrl":"https://doi.org/10.1177/01455613251333644","url":null,"abstract":"<p><strong>Objective: </strong>The use of mastoid pressure dressings (MPDs) after otologic surgery has been a standard practice for decades, believed to minimize complications such as hematoma and wound infection. However, the efficacy of MPDs in improving patient outcomes has been questioned. This study aimed to evaluate the necessity and impact of MPDs on postoperative pain, complications, and overall patient comfort.</p><p><strong>Method: </strong>In this prospective, randomized, controlled trial, 200 patients undergoing major ear surgeries were randomly assigned to receive either a MPD group or a non-MPD (NMPD) group. Postoperative pain was assessed using the Visual Analog Scale at the 3rd, 6th, and 24th hour. Complications, including hematoma, wound infection, and skin erythema, were systematically recorded.</p><p><strong>Results: </strong>Patients in the MPD group reported significantly-higher pain levels at all measured intervals than in the NMPD group (<i>P</i> < .05). Complications such as skin erythema and auricular bruising were more prevalent in the MPD group. Importantly, there was no significant difference between the two groups in the incidence of hematomas or wound infections.</p><p><strong>Conclusion: </strong>The findings suggest that MPDs may contribute to increased postoperative pain and discomfort without offering significant benefits in preventing complications. Given the lack of significant benefit and the increased patient discomfort observed with MPDs, their routine use in otologic surgery may warrant reconsideration. Future research should further explore optimal postoperative care strategies to enhance patient comfort and outcomes.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251333644"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Barriers to Timely Care: Understanding Delayed Health-Seeking Behavior in Chronic Otitis Media Patients in India. 及时护理的障碍:了解印度慢性中耳炎患者的延迟就医行为。
Ear, nose, & throat journal Pub Date : 2025-04-02 DOI: 10.1177/01455613251331837
Aysha Shirin Konari, Saikat Sammadar, Subhradeb Biswas
{"title":"Barriers to Timely Care: Understanding Delayed Health-Seeking Behavior in Chronic Otitis Media Patients in India.","authors":"Aysha Shirin Konari, Saikat Sammadar, Subhradeb Biswas","doi":"10.1177/01455613251331837","DOIUrl":"https://doi.org/10.1177/01455613251331837","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251331837"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143775081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Riedel's Thyroiditis and Noninvasive Follicular Neoplasm With Papillary-Like Nuclear Features: A unique coexistence and diagnostic challenge. 里德尔甲状腺炎和具有乳头状核特征的非侵袭性滤泡肿瘤:一种独特的共存和诊断挑战。
Ear, nose, & throat journal Pub Date : 2025-04-02 DOI: 10.1177/01455613251329662
Monia Ghammam, Jihène Houas, Taissir Ben Arfi, Nassim Ben Hadj-Slama, Hamza Elfekih, Dorra Chiba, Yosra Hasni, Badreddine Sriha, Mohamed Abdelkefi
{"title":"Riedel's Thyroiditis and Noninvasive Follicular Neoplasm With Papillary-Like Nuclear Features: A unique coexistence and diagnostic challenge.","authors":"Monia Ghammam, Jihène Houas, Taissir Ben Arfi, Nassim Ben Hadj-Slama, Hamza Elfekih, Dorra Chiba, Yosra Hasni, Badreddine Sriha, Mohamed Abdelkefi","doi":"10.1177/01455613251329662","DOIUrl":"https://doi.org/10.1177/01455613251329662","url":null,"abstract":"<p><p>Riedel's thyroiditis is a rare inflammatory disease characterized by extensive fibrosis, often mimicking malignancy. The concurrent presence of Riedel's thyroiditis with noninvasive follicular neoplasm with papillary-like nuclear features (NIFTP) is exceptionally rare and has not been previously reported. A 63-year-old male presented with an acute onset anterior cervical mass, fever, and dysphagia. Imaging revealed a large cystic mass in the right thyroid lobe extending into the mediastinum. Initial treatment with antibiotics led to partial improvement, but persistent swelling necessitated a deferred total thyroidectomy. Intraoperatively, the thyroid gland was fibrotic and adherent to surrounding structures. Histopathological examination confirmed Riedel's thyroiditis with extrathyroidal extension and an underlying NIFTP. Postoperatively, the patient developed left vocal cord paresis and primary hypoparathyroidism. Systemic fibrotic involvement was ruled out through a thoracoabdominal-pelvic computed tomography (CT) scan. This case highlights the diagnostic challenges, atypical presentation, and management strategies of this unique coexistence, initially masquerading as a thyroid abscess.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251329662"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143775084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Suppurative Thyroiditis Extending to Retropharyngeal Space: Report of 2 Cases. 急性化脓性甲状腺炎延及咽后间隙2例报告。
Ear, nose, & throat journal Pub Date : 2025-04-01 DOI: 10.1177/01455613251331704
Asimakis D Asimakopoulos, Eugénie Delaine, Avinash Beharry, Salim Bouayed, François Gorostidi
{"title":"Acute Suppurative Thyroiditis Extending to Retropharyngeal Space: Report of 2 Cases.","authors":"Asimakis D Asimakopoulos, Eugénie Delaine, Avinash Beharry, Salim Bouayed, François Gorostidi","doi":"10.1177/01455613251331704","DOIUrl":"https://doi.org/10.1177/01455613251331704","url":null,"abstract":"<p><p>Acute suppurative thyroiditis (AST) is a rare endocrine emergency, typically of bacterial origin, that can lead to significant morbidity and life-threatening complications. It is far less common than other inflammatory thyroid conditions, such as subacute thyroiditis, and may mimic noninfectious inflammatory disorders. Case 1 describes a 40-year-old man with a 5-day history of anterior neck swelling and odynophagia. Physical examination and imaging confirmed AST with retropharyngeal space involvement. He was treated with broad-spectrum intravenous antibiotics and thyroid abscess aspiration. Case 2 involved a patient with an 11-day history of fever and odynophagia. Imaging, including computed tomography and neck ultrasound, revealed a left thyroid lobe abscess extending into the retropharyngeal space. Further evaluation led to the diagnosis of a fourth branchial cleft cyst and a left pyriform fossa sinus tract. A multidisciplinary approach successfully managed both the acute infection and the underlying anatomical anomaly. Retropharyngeal extension of suppurative thyroiditis is exceedingly rare but signifies a severe disease progression with complex clinical implications. This report highlights the need to consider suppurative thyroiditis in the differential diagnosis of midline cervical infections.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251331704"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anaplastic Transformation in Papillary Thyroid Carcinoma: A Case Report. 甲状腺乳头状癌的无性变:病例报告
Ear, nose, & throat journal Pub Date : 2025-04-01 Epub Date: 2024-01-20 DOI: 10.1177/01455613231225872
Young Sang Lyu, Ran Hong, Jeonghyun Oh
{"title":"Anaplastic Transformation in Papillary Thyroid Carcinoma: A Case Report.","authors":"Young Sang Lyu, Ran Hong, Jeonghyun Oh","doi":"10.1177/01455613231225872","DOIUrl":"10.1177/01455613231225872","url":null,"abstract":"<p><p>Anaplastic thyroid cancer (ATC), a rare thyroid malignancy, accounts for only 5% of all thyroid cancers. However, it is the most aggressive form and has a very poor prognosis. Increasing evidence suggests that ATC arises from papillary thyroid carcinoma (PTC). However, the exact mechanism underlying this transformation remains unclear. In almost all cases, ATC originates within, but rarely outside, the thyroid gland. Transformation of metastatic PTC into ATC within the cervical lymph nodes is extremely rare. In this report, we present a rare case in a 63-year-old male patient who was initially diagnosed with PTC at his first hospital visit, which underwent anaplastic transformation in lymph node metastasis, and was subsequently diagnosed during the follow-up visit.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"228-231"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139513925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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