Ear, nose, & throat journal最新文献

{"title":"Facial Nerve Paralysis in Keratosis Obturans: A Systematic Review of Clinical Patterns, Management Outcomes, and Prognostic Insights.","authors":"Yasser Al-Ghabra, Ahmad Alkheder, Mohammad Hamdi, Adel Azar, Adham Bader Aldeen Mohsen, Abdulmajeed Yousfan","doi":"10.1177/01455613251349608","DOIUrl":"https://doi.org/10.1177/01455613251349608","url":null,"abstract":"<p><strong>Objectives: </strong>This review consolidates all reported cases of facial nerve paralysis (FNP) complicating keratosis obturans (KO), a rare disorder characterized by keratin accumulation in the external auditory canal. The study aims to analyze clinical patterns, diagnostic findings, management outcomes, and prognostic factors to enhance understanding and guide evidence-based management of this underrecognized complication.</p><p><strong>Methods: </strong>A comprehensive literature search of PubMed, Web of Science, Scopus, and Google Scholar (inception-December 2024) identified English-language case reports and observational studies linking KO to FNP. Two reviewers independently screened titles/abstracts, performed full-text assessments, and extracted data on demographics, clinical features, imaging, interventions, and outcomes.</p><p><strong>Results: </strong>Seven cases (mean age: 32.4 years; 57.1% female) were analyzed. All exhibited left-sided FNP, with House-Brackmann grades III to VI at presentation. Hearing loss (71.4%) and keratin debris on otoscopy (71.4%) were common. High-resolution computed tomography (HRCT) revealed bony erosion (28.6%-57.1%) and soft-tissue involvement (57.1%). Surgical intervention (85.7%), primarily debridement or mastoidectomy, resulted in complete/partial FNP recovery in 85.7% of cases, while conservative management (14.3%) also showed improvement. Limitations of this review included the small number of cases, heterogeneity in management approaches, and lack of standardized outcome measures.</p><p><strong>Conclusion: </strong>KO-related FNP, though rare, carries significant morbidity. Timely surgical decompression or conservative care may reverse neural injury, emphasizing early diagnosis via clinical-radiological correlation. The predominance of left-sided involvement and favorable outcomes postintervention warrant further investigation. Prospective studies are needed to establish standardized protocols and validate these findings in larger cohorts.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251349608"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Outcomes of Medical Treatment of Adenotonsillar Hypertrophy in Children With Obstructive Sleep Disordered Breathing.","authors":"Andrew C Li, Glenn Isaacson","doi":"10.1177/01455613251350660","DOIUrl":"https://doi.org/10.1177/01455613251350660","url":null,"abstract":"<p><strong>Objective: </strong>Adenotonsillectomy is widely recognized as first-line treatment for obstructive sleep disordered breathing (oSDB), especially for older children with severe disease. The best course of treatment for children with milder oSDB is less clear. It has been our practice to offer surgical candidates with mild symptoms (snoring with occasional short, infrequent pauses by parental report) the option of medical treatment with an antibiotic and oral steroid. We examine the immediate and long term-effects of this intervention.</p><p><strong>Methods: </strong>We reviewed the records of children presenting to our academic Pediatric Otolaryngology practice in the years 2000 to 2023. Tonsil size before and after treatment, resolution of snoring, and ultimate need for surgery were recorded. Follow-up phone calls were made to patient families when information was incomplete.</p><p><strong>Results: </strong>One hundred sixty-nine patients underwent medical treatment for mild oSDB. Among children with acute (≤2 months) symptoms, 38% (20/53) had resolution of snoring and 42% (18/43) did not require surgery. Mean tonsil size (Brodsky grade) decreased from 2.58 to 2.20 after medical treatment in this group. Among children with chronic symptoms, 34% (26/77) had resolution of snoring and 30.0% (18/60) did not require surgery. Their mean tonsil size decreased from 2.58 to 2.13.</p><p><strong>Conclusions: </strong>These results suggest that treatment of mild oSDB treatment with short-course amoxicillin-clavulanate and 5 days of prednisolone is safe and can result in resolution of snoring in many children. More than one third of children treated this way avoided surgery with follow-up averaging 5 years. These observations argue for a prospective, randomized trial of this medical treatment as an alternative to immediate surgery.</p><p><strong>Level of evidence: </strong>3 - retrospective review.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251350660"},"PeriodicalIF":0.0,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Cause of Pediatric Facial Paralysis: Facial Colliculus Syndrome Secondary to Multiple Sclerosis Plaque.","authors":"Muhammet Sefa Acar, Gökhan Polat","doi":"10.1177/01455613251349344","DOIUrl":"https://doi.org/10.1177/01455613251349344","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251349344"},"PeriodicalIF":0.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mid-Glottic Web in a Professional Voice User in the Setting of Upper Respiratory Infection.","authors":"Corinne Negvesky, Sophia Chen, Travis L Shiba","doi":"10.1177/01455613251347916","DOIUrl":"https://doi.org/10.1177/01455613251347916","url":null,"abstract":"<p><p>Mid-glottic webs are a rare pathology of the vocal folds, with cases only documented within the last decade. The pathophysiology behind the location of this vocal fold lesion may be attributed to the mid-vocal fold being the site of maximal mechanical stress during phonation. While anterior glottic webs and posterior glottic stenosis are well-described vocal fold pathologies, only 4 cases of mid-membranous webs have been reported to date. We present the first case of a mid-glottic web not attributable to smoking, radiation, or intubation, in a 45-year-old female teacher who developed chronic dysphonia in the setting of occupational voice use and prior upper respiratory tract infection. She was treated surgically with cold instrument lysis of the adhesion via microdirect laryngoscopy. Her dysphonia improved without residual web at her 4-month postoperative visit, but she did develop vocal fold nodules. A thorough evaluation of acute dysphonia and dyspnea in heavy voice users should include a workup for this rare laryngeal pathology, particularly given its significant negative impact on the ability of occupational voice users to work, followed by proper postoperative voice therapy and vocal hygiene.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251347916"},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144277129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Canine-Transmitted Postoperative <i>Staphylococcus schleiferi</i> Sinusitis.","authors":"Helena C Cabrera, Jeffrey D Suh, Rebecca D Golgert, Jakob L Fischer","doi":"10.1177/01455613251349619","DOIUrl":"https://doi.org/10.1177/01455613251349619","url":null,"abstract":"<p><p>We present the first documented acute bacterial sinus infection with <i>Staphylococcus schleiferi</i> in a 58-year-old male recovering from endoscopic sinus surgery recovering on postoperative oral corticosteroids. The patient reported, within 1 month of surgery, treating an outer ear infection in his dog that was culture positive for <i>Staphylococcus schleiferi</i> and <i>Corynebacterium sp.</i> and developing an acute exacerbation of his sinus symptoms with increased purulent drainage, facial pain, and increased aural fullness. Nasal endoscopy was notable for purulence and thick mucus in multiple sinuses, which was positive on culture for <i>S. schleiferi</i>. He underwent treatment with trimethoprim/sulfamethoxazole that resolved the active infection. <i>S. schleiferi</i> has shown only rare transmission to a human host in both immunocompetent and immunocompromised patients. Often, this bacterial pathogen will present as a skin infection or outer ear infection in canines and serves as the potential source of infection in humans as they treat their canine companions. This marks the first documented case of acute bacterial sinusitis caused by this bacterial pathogen in the human literature and warrants continued observation as another potential zoonotic pathogen that may cause sinus exacerbations in susceptible populations.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251349619"},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144277128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Allergic Fungal Rhinosinusitis: A Contemporary Update.","authors":"Matthew Y Liu, Philip G Chen, Erik K Weitzel, Erin M Lopez","doi":"10.1177/01455613251346578","DOIUrl":"https://doi.org/10.1177/01455613251346578","url":null,"abstract":"<p><strong>Objectives: </strong>To provide a contemporary update on the pathophysiology, diagnosis, and treatment of allergic fungal rhinosinusitis (AFRS).</p><p><strong>Methods: </strong>A review article on the pathophysiology, diagnosis, and treatment of AFRS was performed.</p><p><strong>Results: </strong>AFRS is a subtype of chronic rhinosinusitis with nasal polyps characterized by noninvasive fungal hyphae, eosinophilic mucin, and a type 2 inflammatory response, resulting in significant clinical and radiographic presentations. Although a diagnostic criterion has been used since the 1990s, advances in the pathophysiology and treatment of AFRS question the specificity and applicability of such criteria. Furthermore, the development and progression of AFRS are closely associated with the social determinants of health (SDOH) with a possible genetic component that limits sinonasal antifungal activity. Surgery followed by topical corticosteroids and nasal saline irrigations remains the mainstay of treatment with immunotherapy, antifungals, and biologics having a potential role.</p><p><strong>Conclusions: </strong>AFRS is a complex sinonasal inflammatory disease influenced by socioeconomic, genetic, and environmental factors. Future research is needed to investigate the influence of the SDOH on AFRS, advance diagnostic methods to optimize utility in everyday clinical practice and research, and elucidate the role of potential novel medical therapies in the current treatment pathway.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251346578"},"PeriodicalIF":0.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Co-Existence of Isolated Sphenoidal Fungal Rhinosinusitis and Sphenochoanal Polyp.","authors":"Mainak Dutta, Mousam Maiti, Henna Ali, Arundhati Mukherjee, Mebarimon Kharwanlang, Kirubakaran Kothandaraman","doi":"10.1177/01455613251348312","DOIUrl":"https://doi.org/10.1177/01455613251348312","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251348312"},"PeriodicalIF":0.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Nomogram to Predict the Risk of External Auditory Canal Stenosis After Endoscopic Surgery: A Retrospective Study\".","authors":"Rachana Mehta, Ranjana Sah","doi":"10.1177/01455613251347845","DOIUrl":"https://doi.org/10.1177/01455613251347845","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251347845"},"PeriodicalIF":0.0,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary Facial Cutaneous Mucormycosis in a 6 Month-Old Infant: Case Report With Literature Review.","authors":"Yasser ALGhabra, Hossam Alhraki, Vivian Alahmad, Hisham Alshwaikh","doi":"10.1177/01455613251348315","DOIUrl":"https://doi.org/10.1177/01455613251348315","url":null,"abstract":"<p><p>Cutaneous mucormycosis, a rare and life-threatening fungal infection caused by <i>Mucorales</i> species, predominantly affects immunocompromised individuals. This report describes a rapidly progressive case in a 6-month-old immunocompetent infant who presented with necrotic facial lesions progressing to extensive eschar over 2 weeks. Despite prompt histopathological confirmation, radical surgical debridement, and immediate liposomal amphotericin B therapy, the infant succumbed to sudden deterioration 3 months after apparent clinical resolution. Initial biopsies confirmed cutaneous mucormycosis with characteristic broad, pauci-septate hyphae, while repeat biopsies at 1 month showed no residual disease. Laboratory and imaging findings were unremarkable, and fungal cultures remained negative. This case highlights the diagnostic and therapeutic challenges of pediatric mucormycosis, particularly in immunocompetent hosts, and underscores the potential for fatal relapse despite adherence to treatment protocols. The paradoxical outcome emphasizes the need for prolonged antifungal therapy, advanced molecular monitoring, and equitable access to diagnostics in resource-limited settings.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251348315"},"PeriodicalIF":0.0,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Surgery Approaches in Laryngopharyngeal Schwannomas: A Retrospective Analysis.","authors":"Yajun Gu, Zheng Liang, Hao Wei, Junguo Wang, Hui Li, Hao Wu, Ao Li, Xiaoyun Qian","doi":"10.1177/01455613251346588","DOIUrl":"https://doi.org/10.1177/01455613251346588","url":null,"abstract":"<p><strong>Purpose: </strong>Laryngeal schwannoma is a rare condition with limited research. This case series presents cases of laryngeal schwannoma in our department with details on the surgical approaches and prognosis of patients, in order to add more evidence for this setting.</p><p><strong>Methods: </strong>The patients presented with symptoms that suggested diseases in the throat. These patients were examined by laryngoscopy, magnetic resonance imaging (MRI), and computed tomography (CT). Depending on the tumor size and location, trans-oral endoscopic (laser-assisted) resection, or open laryngeal surgery was applied. The open surgery was modified by splitting the thyroid cartilage plate in the middle (not entering the larynx) and separating the inner surface of the thyroid cartilage plate on the affected side.</p><p><strong>Results: </strong>The tumors of all patients were successfully removed. Then, these patients were followed up at the 1st, 3rd, and 6th month after surgery through clinic visits. Laryngoscopy, MRI, and CT were performed to examine the patients, and no recurrences were detected.</p><p><strong>Conclusion: </strong>The changes applied for the procedure presented in the present study have the potential to reduce recovery time and scarring, and help preserve throat function. The investigators consider these as potential alternatives to existing methods for treating laryngeal schwannomas. However, more research is required to refine the methods used to treat schwannomas and to ensure that patients receive the best care.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251346588"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}