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[Treatment of chronic kidney disease in IgA nephropathy]. [IgA肾病慢性肾病的治疗]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-01-01 Epub Date: 2025-01-14 DOI: 10.1055/a-2255-6329
Severin Schricker, Moritz Schanz, Jörg Latus
{"title":"[Treatment of chronic kidney disease in IgA nephropathy].","authors":"Severin Schricker, Moritz Schanz, Jörg Latus","doi":"10.1055/a-2255-6329","DOIUrl":"https://doi.org/10.1055/a-2255-6329","url":null,"abstract":"<p><p>This article provides an overview of treatment approaches for chronic kidney disease (CKD) in patients with IgA nephropathy (IgAN). IgAN is the most common primary glomerulonephritis and results from an autoimmune reaction to aberrantly glycosylated immunoglobulin A (IgA) antibodies. Although historically considered largely benign, it is now recognized that a significant percentage of patients develop dialysis-dependent kidney disease over the years. Traditional treatments with RAAS inhibitors and newer therapies such as SGLT2 inhibitors, endothelin receptor antagonists, and delayed release, primarily locally acting enteric corticosteroids regarding their role in reducing proteinuria and preserving kidney function are also discussed. Additionally, non-immunosuppressive options and lifestyle modifications are examined for their potential to slow disease progression. Further promising medications are currently in clinical trials, including complement inhibitors and immunomodulators. These emerging therapies offer hope for significantly improving the prognosis of IgAN in the future. By presenting a comprehensive overview of current and potential future treatment strategies, this review aims to provide clinicians with up-to-date information to optimize the management of CKD in patients with IgAN.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 3","pages":"83-90"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Acutely Altered Mental Status: When the Patient is Acting Odd]. [急性精神状态改变：当病人行为怪异时]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-01-01 Epub Date: 2024-12-11 DOI: 10.1055/a-2360-0999
Zoi Netou-Kandylidou
{"title":"[Acutely Altered Mental Status: When the Patient is Acting Odd].","authors":"Zoi Netou-Kandylidou","doi":"10.1055/a-2360-0999","DOIUrl":"https://doi.org/10.1055/a-2360-0999","url":null,"abstract":"<p><p>An acutely altered mental status is a common presenting complaint. A wide variety of neurological, systemic or psychiatric conditions can be the cause. Sometimes there is even overlap of various diseases that contribute to the patient's confusion. The brain can be primarily or secondarily involved. A meticulous history and examination provide the first clues as to the origin of the alternation in personality. Most of the time further exams at the hospital are necessary to determine the diagnosis and plan the treatment. Nevertheless, even with just limited preclinical resources perceptive teams are able to gather and analyse enough information to diagnose and treat the patient. The result of this detective work can be quite rewarding, especially if the initial diagnosis is confirmed. Therapeutic measures preclinically focus on maintaining the cerebral equilibrium.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 1-02","pages":"53-63"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Deutsche Medizinische Wochenschrift - 150 years of nephrology in the DMW]. [德国医学杂志- 150年肾脏病在DMW]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-12-01 Epub Date: 2024-12-04 DOI: 10.1055/a-2309-8315
Andreas Kribben, Elif Karakurt
{"title":"[Deutsche Medizinische Wochenschrift - 150 years of nephrology in the DMW].","authors":"Andreas Kribben, Elif Karakurt","doi":"10.1055/a-2309-8315","DOIUrl":"https://doi.org/10.1055/a-2309-8315","url":null,"abstract":"<p><p>Since its founding 150 years ago, the Deutsche Medizinische Wochenschrift has continually followed the developments in nephrology through countless publications. Pioneers in nephrology like Franz Volhard and Georg Haas were authors of the DMW, and new hypotheses, examination methods, and therapies were often debated here, as this article shows.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 24-25","pages":"1536-1545"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Endocrinology, diabetology and metabolism in the 150 years of the DMW - A long and sustainable relationship]. [内分泌学，糖尿病学和新陈代谢在150年的DMW -一个长期和可持续的关系]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-12-01 Epub Date: 2024-12-04 DOI: 10.1055/a-2339-0591
Hendrik Lehnert, Klaus Mann
{"title":"[Endocrinology, diabetology and metabolism in the 150 years of the DMW - A long and sustainable relationship].","authors":"Hendrik Lehnert, Klaus Mann","doi":"10.1055/a-2339-0591","DOIUrl":"https://doi.org/10.1055/a-2339-0591","url":null,"abstract":"<p><p>The DMW is celebrating its 150th anniversary - and this period is precisely when endocrinology and diabetology evolved from the first experiments to molecular biology, genetic, and bioinformatics research. The DMW has always accompanied this process with numerous important publications, some of which are highlighted in this article.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 24-25","pages":"1492-1499"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Developments in intensive care medicine as reflected in the Deutsche Medizinische Wochenschrift]. [重症监护医学的发展反映在德国医学杂志上]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-12-01 Epub Date: 2024-12-04 DOI: 10.1055/a-2291-2053
Matthias Kochanek, Uwe Janssens
{"title":"[Developments in intensive care medicine as reflected in the Deutsche Medizinische Wochenschrift].","authors":"Matthias Kochanek, Uwe Janssens","doi":"10.1055/a-2291-2053","DOIUrl":"https://doi.org/10.1055/a-2291-2053","url":null,"abstract":"<p><p>The developments in intensive care medicine documented in the Deutsche Medizinische Wochenschrift over the decades have significantly improved survival rates in severe conditions and pushed the boundaries of what is possible in acute medicine. By analyzing past issues and articles, this article shows how the Deutsche Medizinische Wochenschrift has acted as a mirror of the dynamic landscape of intensive care medicine.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 24-25","pages":"1514-1525"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[150 years of "remodeling" in internal medicine and cardiology as reflected in the DMW]. [在DMW中反映的内科和心脏病学150年的“重塑”]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-12-01 Epub Date: 2024-12-04 DOI: 10.1055/a-2289-3859
Georg Ertl
{"title":"[150 years of \"remodeling\" in internal medicine and cardiology as reflected in the DMW].","authors":"Georg Ertl","doi":"10.1055/a-2289-3859","DOIUrl":"https://doi.org/10.1055/a-2289-3859","url":null,"abstract":"<p><p>This article reflects 150 years of medical progress, particularly in internal medicine and cardiology, which have been accompanied and documented by the Deutsche Medizinische Wochenschrift (DMW). A fascinating look back at the exciting development of this specialist field and an outlook on future possibilities.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 24-25","pages":"1475-1480"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[150 years of gastroenterology in the DMW - from Kussmaul to AI]. [150年的胃肠病学在DMW -从Kussmaul到AI]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-12-01 Epub Date: 2024-12-04 DOI: 10.1055/a-2304-8004
Robert Thimme, Hubert Erich Blum
{"title":"[150 years of gastroenterology in the DMW - from Kussmaul to AI].","authors":"Robert Thimme, Hubert Erich Blum","doi":"10.1055/a-2304-8004","DOIUrl":"https://doi.org/10.1055/a-2304-8004","url":null,"abstract":"<p><p>The Deutsche Medizinische Wochenschrift has accompanied the diverse and dynamic developments in the field of gastroenterology since the first issue of the journal in 1875! This article examines gastroenterological publications that have been published in the DMW over its 150-year history - some of which have marked milestones in this medical field.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 24-25","pages":"1526-1530"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[From research to professional education: The DMW from 1975 to 2025]. [从研究到专业教育：1975年至2025年的DMW]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-12-01 Epub Date: 2024-12-04 DOI: 10.1055/a-2306-2694
Niklas Feix, Heiner Fangerau, Nils Hansson
{"title":"[From research to professional education: The DMW from 1975 to 2025].","authors":"Niklas Feix, Heiner Fangerau, Nils Hansson","doi":"10.1055/a-2306-2694","DOIUrl":"https://doi.org/10.1055/a-2306-2694","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 24-25","pages":"1468-1474"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Angiology yesterday and today: vascular sonography and catheter intervention]. [血管学的昨天和今天：血管超声和导管介入]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-12-01 Epub Date: 2024-12-04 DOI: 10.1055/a-2298-0504
Ulrich Hoffmann
{"title":"[Angiology yesterday and today: vascular sonography and catheter intervention].","authors":"Ulrich Hoffmann","doi":"10.1055/a-2298-0504","DOIUrl":"https://doi.org/10.1055/a-2298-0504","url":null,"abstract":"<p><p>The specialist in angiology was introduced into the discipline of internal medicine in 1992. In the previous decades, the technical methods in angiology were still very limited. However, duplex sonography and endovascular catheter interventions then revolutionized the diagnostic and therapeutic spectrum. Today, multiparametric vascular sonography and modern catheter procedures are an integral part of diagnostics and therapy.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 24-25","pages":"1487-1491"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Development and significance of geriatrics as reflected in the Deutsche Medizinische Wochenschrift]. [德国医学杂志反映的老年病学的发展和意义]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-12-01 Epub Date: 2024-12-04 DOI: 10.1055/a-2307-1394
Walter Swoboda, Cornel Sieber
{"title":"[Development and significance of geriatrics as reflected in the Deutsche Medizinische Wochenschrift].","authors":"Walter Swoboda, Cornel Sieber","doi":"10.1055/a-2307-1394","DOIUrl":"https://doi.org/10.1055/a-2307-1394","url":null,"abstract":"<p><p>The \"Deutsche Medizinische Wochenschrift\" (DMW) is one of the oldest and most respected medical journals in Germany. Since its foundation in 1875, it has played a central role in the dissemination of medical research and practice. Its significance for geriatrics is far-reaching. The DMW has not only contributed to the dissemination of new research findings and treatment methods, but has also promoted the development and recognition of geriatrics as an independent medical specialty.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 24-25","pages":"1531-1535"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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