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Deutsche medizinische Wochenschrift (1946)最新文献

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[Pacing in a 59-year-old female patient with post-Covid syndrome - a model for self-directed rehabilitation]. [科维德综合征后 59 岁女性患者的起搏--自我指导康复的典范]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-09-01 Epub Date: 2024-09-09 DOI: 10.1055/a-2373-5038
Lienhard Dieterle, Hans Richter
{"title":"[Pacing in a 59-year-old female patient with post-Covid syndrome - a model for self-directed rehabilitation].","authors":"Lienhard Dieterle, Hans Richter","doi":"10.1055/a-2373-5038","DOIUrl":"https://doi.org/10.1055/a-2373-5038","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 19","pages":"1159-1162"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Joint pain - a rheumatic disease?] [关节疼痛--风湿病？]
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-09-01 Epub Date: 2024-09-09 DOI: 10.1055/a-2329-6673
Frank Moosig, Julia U Holle
{"title":"[Joint pain - a rheumatic disease?]","authors":"Frank Moosig, Julia U Holle","doi":"10.1055/a-2329-6673","DOIUrl":"10.1055/a-2329-6673","url":null,"abstract":"<p><p>Pain in the musculoskeletal system and therefore joint pain is one of the most common reasons for consulting a general practitioner (GP). Inflammatory rheumatic diseases are among the important differential diagnoses. However, the prevalence of rheumatological diseases is significantly lower than that of degenerative causes of pain. Incorrect referrals can be avoided if the causes of pain are better differentiated in GP practices. This article presents the first differential diagnostic steps that make it easier for the GP to make further treatment decisions. Physical examination, laboratory diagnostics and imaging are discussed, and the concept of \"clinically suspect arthralgia\" as well as the possible effects of treatment trials with glucocorticoids are presented.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 19","pages":"1163-1173"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Multi-resistant pathogens - are they also resistant to disinfectants?] [多重抗药性病原体--它们对消毒剂也有抗药性吗？］
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-09-01 Epub Date: 2024-09-09 DOI: 10.1055/a-2250-0901
Johannes Knobloch, Birte Knobling
{"title":"[Multi-resistant pathogens - are they also resistant to disinfectants?]","authors":"Johannes Knobloch, Birte Knobling","doi":"10.1055/a-2250-0901","DOIUrl":"10.1055/a-2250-0901","url":null,"abstract":"<p><p>Epidemiological studies show that the care of patients in rooms with a previous stay by a person with evidence of multi-resistant pathogens (MRP) is associated with an increased risk of these pathogens occurring. The question therefore regularly arises as to whether MRP also exhibit resistance to the disinfectants used. To date, there are no standardised definitions for \"resistance\" to disinfectants. However, disinfectants authorised on the market are also effective against multi-resistant pathogens and the failure of efficient disinfection is mainly caused by application errors (insufficient cleaning, incomplete wetting, incorrect application concentration or exposure time etc.). The effectiveness of disinfectants depends on a variety of environmental factors (especially accompanying contamination). A reduced sensitivity to disinfectants can occur in individual isolates due to selection under sub-inhibitory concentrations of disinfectants. Resistance mechanisms to antibiotics do not mediate cross-resistance to disinfectants, but a change in the permeability of bacterial cells can influence sensitivity to disinfectants and antibiotics. In general, the success of routine disinfection can be improved by suitable process controls and contribute to reducing the transmission of MRP.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 19","pages":"1151-1157"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Small intestinal bacterial overgrowth (SIBO) - Therapy, nutrition, microbiome]. [小肠细菌过度生长 (SIBO) - 治疗、营养、微生物组]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-09-01 Epub Date: 2024-08-29 DOI: 10.1055/a-2205-5794
Gernot Sellge, Johann Ockenga
{"title":"[Small intestinal bacterial overgrowth (SIBO) - Therapy, nutrition, microbiome].","authors":"Gernot Sellge, Johann Ockenga","doi":"10.1055/a-2205-5794","DOIUrl":"https://doi.org/10.1055/a-2205-5794","url":null,"abstract":"<p><p>SIBO (small intestinal bacterial overgrowth) is defined by bacterial overgrowth or colonization of the small intestine in combination with gastrointestinal symptoms such as bloating, nausea, pain, diarrhoea, malabsorption and food intolerance. SIBO can be caused by various mechanisms such as reduced intestinal motility, altered gastrointestinal anatomy, reduced gastric acid or pancreatic enzyme production, altered bile acid metabolism, or immune defects. Accordingly, SIBO often develops secondary to different underlying diseases.Diet has a fundamental influence on the composition of the intestinal microbiome and is therefore also a potential pathomechanism in SIBO. Furthermore, food intolerances are common in SIBO patients. However, both aspects have so far been insufficiently investigated. Nevertheless, elemental diets, carbohydrate-reduced diets, as well as pre- and probiotics are potential therapy options.This article provides a summary of current knowledge on the pathophysiology, diagnosis and treatment of SIBO, with particular emphasis on the role of nutrition and the microbiome.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 18","pages":"1071-1079"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142116328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[69-year old patient with chronic polyarthralgia]. [69岁慢性多关节痛患者]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-09-01 Epub Date: 2024-09-09 DOI: 10.1055/a-2333-1837
Nils Schulz, Philipp Klemm
{"title":"[69-year old patient with chronic polyarthralgia].","authors":"Nils Schulz, Philipp Klemm","doi":"10.1055/a-2333-1837","DOIUrl":"https://doi.org/10.1055/a-2333-1837","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 19","pages":"1131-1132"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Food allergies: A diagnostic challenge of increasing importance]. [食物过敏：日益重要的诊断挑战]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-09-01 Epub Date: 2024-08-29 DOI: 10.1055/a-2180-0138
Raja Atreya
{"title":"[Food allergies: A diagnostic challenge of increasing importance].","authors":"Raja Atreya","doi":"10.1055/a-2180-0138","DOIUrl":"https://doi.org/10.1055/a-2180-0138","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 18","pages":"1059"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142116423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum: Differenzialdiagnose und Therapie der Immunthrombozytopenie. 勘误：免疫性血小板减少症的鉴别诊断和治疗。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-08-08 DOI: 10.1055/a-2381-4927
Aristoteles Giagounidis
{"title":"Erratum: Differenzialdiagnose und Therapie der Immunthrombozytopenie.","authors":"Aristoteles Giagounidis","doi":"10.1055/a-2381-4927","DOIUrl":"https://doi.org/10.1055/a-2381-4927","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141908683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Fiber endoscopic evaluation of swallowing (FEES) - an important tool for diagnosing myasthenia gravis]. [纤维内窥镜吞咽评估（FEES）--诊断重症肌无力的重要工具]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-08-01 Epub Date: 2024-08-15 DOI: 10.1055/a-2352-5193
Michael Kowar, Monika Frackowiak, Christiane Kaufhold, Andreas H Jacobs
{"title":"[Fiber endoscopic evaluation of swallowing (FEES) - an important tool for diagnosing myasthenia gravis].","authors":"Michael Kowar, Monika Frackowiak, Christiane Kaufhold, Andreas H Jacobs","doi":"10.1055/a-2352-5193","DOIUrl":"https://doi.org/10.1055/a-2352-5193","url":null,"abstract":"<p><strong>History and admission findings: </strong> A 76-year old man was admitted with a globus sensation and weight loss for further investigations to our geriatric ward. A gastroscopic evaluation executed before had been unremarkable.</p><p><strong>Investigations: </strong> Physical examination was unremarkable, including a neurological examination.</p><p><strong>Treatment and course: </strong> All radiological findings (computer tomography of chest, abdomen and neck) were unremarkable. In a FEES investigation we found retentions and a reduction of frequency of swallowing after a while. During the investigation the patient complained about a muscular weakness in his neck. The assumed diagnosis of a myasthenia gravis was confirmed by antibodies against acetylcholine receptors and a decrement in repetitive irritation of the orbicularis and trapezius muscle.</p><p><strong>Conclusion: </strong> FEES can be a valid diagnosis tool for a pharyngeal type of a myasthenia gravis.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 17","pages":"997-1001"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Polymyalgia rheumatica: What's new?] [多发性风湿病：有什么新进展？］
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-08-01 Epub Date: 2024-08-15 DOI: 10.1055/a-2144-8222
Wolfgang A Schmidt
{"title":"[Polymyalgia rheumatica: What's new?]","authors":"Wolfgang A Schmidt","doi":"10.1055/a-2144-8222","DOIUrl":"https://doi.org/10.1055/a-2144-8222","url":null,"abstract":"<p><p>Currently, only 25% of all polymyalgia rheumatica (PMR) patients are referred to specialists. An expert committee has recently recommended confirmation of diagnosis by specialist care. This can help to avoid misdiagnoses and hospital stays and can result in lower glucocorticoid doses.Using ultrasound, magnetic resonance imagining (MRI), or positron emission tomography-computed tomography (PET-CT), typical periarticular inflammatory changes are observed, especially in the shoulder and pelvic girdle area. However, for clinical use, ultrasound is usually sufficient.In 20-25% of newly diagnosed PMR patients without symptoms of giant cell arteritis (GCA), GCA can be detected through vascular ultrasound. These patients require higher glucocorticoid doses in analogy to GCA therapy. There is growing awareness of a joint GCA-PMR spectrum disease.Glucocorticoids remain the primary treatment. The interleukin-6 inhibitor Sarilumab has recently been approved in the USA for patients with recurrent PMR. Studies have also demonstrated the effectiveness of Tocilizumab in PMR.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 17","pages":"1051-1055"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Community-Acquired Bacterial Meningoencephalitis: The New Guideline]. [社区获得性细菌性脑膜脑炎：新指南]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-08-01 Epub Date: 2024-08-15 DOI: 10.1055/a-2204-5167
Alexandros Hadjilaou, Manuel Alexander Friese
{"title":"[Community-Acquired Bacterial Meningoencephalitis: The New Guideline].","authors":"Alexandros Hadjilaou, Manuel Alexander Friese","doi":"10.1055/a-2204-5167","DOIUrl":"https://doi.org/10.1055/a-2204-5167","url":null,"abstract":"<p><p>Updating the vaccination recommendations against meningococci and pneumococci, in particular the introduction of the B vaccine as the standard vaccination for infants from January 2024 and the adaptation of the pneumococcal vaccination strategy for infants and adults aged 60 and over with the latest conjugate vaccines (PCV13, PCV15, PCV20).Emphasis on the need for rapid diagnostic lumbar puncture and simultaneous serum and cerebrospinal fluid analysis to increase diagnostic precision. The introduction of procalcitonin (PCT) in serum as an additional biomarker to differentiate between bacterial and viral meningitis.The use of multiplex PCR as a supplement, not a replacement, for standard diagnostics to speed up pathogen identification.Adaptation of antibiotic recommendations based on the current resistance situation, in particular for meningococcal meningitis, consideration of penicillin G only after resistance testing.Clarification of the areas and duration of use of dexamethasone in bacterial meningitis, particularly in pneumococcal meningitis and the controversial data situation in Listeria meningitis.New findings on the safe use of heparin in septic sinus thrombosis without increased risk of hemorrhage.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"149 17","pages":"1021-1027"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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