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Deutsche medizinische Wochenschrift (1946)最新文献

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[(Over-)living with cancer: secondary malignancies (incl. genetics)]. [（过度）癌症患者：继发性恶性肿瘤（包括遗传）]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-01-01 Epub Date: 2024-12-11 DOI: 10.1055/a-2258-4682
Wajma Shahbaz, Philipp A Greif
{"title":"[(Over-)living with cancer: secondary malignancies (incl. genetics)].","authors":"Wajma Shahbaz, Philipp A Greif","doi":"10.1055/a-2258-4682","DOIUrl":"https://doi.org/10.1055/a-2258-4682","url":null,"abstract":"<p><p>Secondary malignancies (secondary cancers) are malignant diseases that occur at a certain time after cancer treatment. The malignant neoplasms can occur anywhere from 2 months to decades after cancer treatment. In addition, multiple tumor diseases can also develop due to a hereditary tendency to tumors. This article provides an overview of the causes, early detection and individual treatment.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 1-02","pages":"37-43"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cancer Survivorship]. (癌症生存)。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-01-01 Epub Date: 2024-12-11 DOI: 10.1055/a-2304-3456
Michael von Bergwelt-Baildon
{"title":"[Cancer Survivorship].","authors":"Michael von Bergwelt-Baildon","doi":"10.1055/a-2304-3456","DOIUrl":"https://doi.org/10.1055/a-2304-3456","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 1-02","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Challenges of chronic kidney disease]. [慢性肾脏病的挑战]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-01-01 Epub Date: 2025-01-14 DOI: 10.1055/a-2255-6563
Mark Dominik Alscher
{"title":"[Challenges of chronic kidney disease].","authors":"Mark Dominik Alscher","doi":"10.1055/a-2255-6563","DOIUrl":"https://doi.org/10.1055/a-2255-6563","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 3","pages":"65"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Psychological support for people with cancer]. [对癌症患者的心理支持]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-01-01 Epub Date: 2024-12-11 DOI: 10.1055/a-2258-1676
Franziska Springer, Anja Mehnert-Theuerkauf
{"title":"[Psychological support for people with cancer].","authors":"Franziska Springer, Anja Mehnert-Theuerkauf","doi":"10.1055/a-2258-1676","DOIUrl":"https://doi.org/10.1055/a-2258-1676","url":null,"abstract":"<p><p>The number of people living with or after cancer is steadily increasing due to an ageing society and improved cancer treatment. However, once treatment has been completed, the consequences of the disease are often felt for a long time. These affect many different areas of life and often lead to a high level of suffering and need for care. Psycho-oncological support offers effective support for many of those affected.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 1-02","pages":"15-21"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Renal replacement therapy in Germany: An overview with a clinical focus]. [德国的肾脏替代疗法：以临床为重点的概述]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-01-01 Epub Date: 2025-01-14 DOI: 10.1055/a-2261-3753
Marc Günther, Susi Knöller
{"title":"[Renal replacement therapy in Germany: An overview with a clinical focus].","authors":"Marc Günther, Susi Knöller","doi":"10.1055/a-2261-3753","DOIUrl":"https://doi.org/10.1055/a-2261-3753","url":null,"abstract":"<p><p>In Germany, around 80000 people are currently dependent on permanent renal replacement therapy (RRT). Due to demographic developments and improvements in life expectancy, the prevalence will continue to increase even if the effects of newer pharmacological substances such as SGLT2 inhibitors and GLP1 agonists are promising in inhibiting progression. There are basically three different methods of renal replacement therapy and their variants: Kidney transplantation (KTX), peritoneal dialysis (PD), hemodialysis (HD)/hemodiafiltration (HDF). The life expectancy of dialysis patients is reduced by around 67% compared to the normal population, particularly due to cardiovascular and infection-related complications. PD and HD are considered to be equivalent in terms of mortality. Currently, HDF is increasingly coming back into focus after the last randomized controlled trial (CONVINCE trial) proved its superiority over conventional HD. Kidney transplantation is clearly superior to dialysis therapy in terms of life expectancy; according to a meta-analysis, the risk of death is reduced by around 55% in comparison.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 3","pages":"91-99"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Long-term organ toxicity of oncological therapies]. [肿瘤治疗的长期器官毒性]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-01-01 Epub Date: 2024-12-11 DOI: 10.1055/a-2258-1737
Melissa S Y Thong, Daniela Doege, Julien Frick, Volker Arndt
{"title":"[Long-term organ toxicity of oncological therapies].","authors":"Melissa S Y Thong, Daniela Doege, Julien Frick, Volker Arndt","doi":"10.1055/a-2258-1737","DOIUrl":"10.1055/a-2258-1737","url":null,"abstract":"<p><p>Cancer treatments, although life prolonging, are associated with side effects. The occurrence, duration, and severity of side effects vary, depending on treatment received. Long-term effects refer to effects that manifest during treatment and persist long after treatment has ended. Late effects are complications that occur after treatment has ended. These effects can have a negative impact on the functioning and quality of life of persons living with and beyond cancer. This overview aims to provide a non-exhaustive overview of the long-term and late effects associated with the traditional mainstay of cancer treatments (surgery, radiotherapy, chemotherapy) and newer treatments such as immunotherapy. In conclusion, long-term and late effects of cancer treatment can be associated with a high burden for those affected, including a reduction in their ability to function and health-related quality of life. Given the large and further growing number of cancer survivors and the abundance of long-term and late effects, it is essential to develop and implement risk-adapted, multidisciplinary survivorship care programmes.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 1-02","pages":"29-36"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Nephritic sediment - step by step]. [肾结石沉积物-一步一步]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-01-01 Epub Date: 2024-12-11 DOI: 10.1055/a-2325-4542
Cornelia Elisabeth Eckert, Dagmar Biegger, Jörg Latus, Fabian Alexander Riegg
{"title":"[Nephritic sediment - step by step].","authors":"Cornelia Elisabeth Eckert, Dagmar Biegger, Jörg Latus, Fabian Alexander Riegg","doi":"10.1055/a-2325-4542","DOIUrl":"https://doi.org/10.1055/a-2325-4542","url":null,"abstract":"<p><p>The examination of urine and its evaluation are central components in the diagnostic pathway for kidney diseases. Essential to this process is the correct analysis and interpretation of the urine sediment. A nephritic sediment indicates glomerular kidney disease with high specificity. This article explains the diagnosis, evaluation, and implications of a nephritic sediment.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 1-02","pages":"48-52"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Ethic dimensions of extracorporeal cardiopulmonary support systems]. [体外心肺支持系统的伦理问题]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-01-01 Epub Date: 2025-01-14 DOI: 10.1055/a-2363-3977
Jochen Dutzmann
{"title":"[Ethic dimensions of extracorporeal cardiopulmonary support systems].","authors":"Jochen Dutzmann","doi":"10.1055/a-2363-3977","DOIUrl":"https://doi.org/10.1055/a-2363-3977","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 3","pages":"106-109"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Atypical spontaneous bacterial peritonitis linked to streptococcal toxic shock syndrome]. [与链球菌中毒性休克综合征有关的非典型自发性细菌性腹膜炎]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-01-01 Epub Date: 2024-12-11 DOI: 10.1055/a-2418-2842
Tomas Marin Cuartas, Ahmad Farid Nasri, Stefan Bollmann
{"title":"[Atypical spontaneous bacterial peritonitis linked to streptococcal toxic shock syndrome].","authors":"Tomas Marin Cuartas, Ahmad Farid Nasri, Stefan Bollmann","doi":"10.1055/a-2418-2842","DOIUrl":"https://doi.org/10.1055/a-2418-2842","url":null,"abstract":"<p><strong>Anamnesis and clinical examination: </strong>A 59-year-old female patient with an unremarkable medical history presented with watery diarrhea, severe lower abdominal pain, and fever for approximately 7 days. Physical examination revealed a distended abdomen, bowel sounds were absent, and there was an acute abdomen with generalized guarding and significantly elevated inflammatory markers.</p><p><strong>Diagnosis: </strong>Abdominal computed tomography showed significant ascites and signs of peritonitis. Exploratory diagnostics were indicated. A laparoscopy was performed, which revealed diffuse purulent peritonitis. Organ perforation or other reasons for a peritonitis were excluded.</p><p><strong>Therapy and clinical course: </strong>Bacteriological examination and blood cultures showed β-hemolytic group A streptococci, leading to the diagnosis of spontaneous bacterial peritonitis caused by streptococci. The patient was treated with antibiotics, progressively recovered, and was discharged symptom-free and without sequelae.</p><p><strong>Conclusion: </strong>Primary spontaneous bacterial peritonitis caused by <i>Streptococcus pyogenes</i> is a rare cause of acute abdomen. An early diagnosis and immediate antibiotic therapy are crucial for prognosis.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 1-02","pages":"44-47"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Chronic Kidney Disease: epidemiology, implications for clinical practice and equations for diagnosis]. [慢性肾脏疾病：流行病学，对临床实践的影响和诊断方程]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-01-01 Epub Date: 2025-01-14 DOI: 10.1055/a-2265-9422
Elke Schaeffner
{"title":"[Chronic Kidney Disease: epidemiology, implications for clinical practice and equations for diagnosis].","authors":"Elke Schaeffner","doi":"10.1055/a-2265-9422","DOIUrl":"https://doi.org/10.1055/a-2265-9422","url":null,"abstract":"<p><p>The article is based, among other things, on the updated KDIGO guideline for the evaluation and management of chronic kidney disease, which was published in Kidney International in March 2024. Chronic kidney disease is one of the most common chronic diseases, with a prevalence of around 10%, not least due to demographic ageing. The incidence of chronic kidney disease is approximately twice that of diabetes and approximately 20 times higher than that of cancer. Chronic kidney disease is classified using glomerular filtration rate and albuminuria. The definition of CKD may also include markers other than GFR and ACR. Patients with diabetes or hypertension should have GFR and ACR tested regularly. The individual risk of kidney failure requiring dialysis can be determined using a prediction equation. A better understanding of age- and gender-specific differences means that personalized therapy approaches are becoming increasingly important. Clinicians should be aware of the limitations of the endogenous biomarkers creatinine and cystatin C for determining GFR. For Germany, the equations of the European Kidney Function Consortium (EKFC) are recommended for estimating GFR.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 3","pages":"77-82"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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