Current health sciences journal最新文献_第6页

Multicenter Epidemiological Study of Nosebleeds Requiring Hospitalization. 需要住院治疗的鼻出血多中心流行病学研究

Current health sciences journal Pub Date : 2023-07-01 Epub Date: 2023-09-30 DOI: 10.12865/CHSJ.49.03.13

Andreea Nicoleta Vlaescu, Elena Ionita, Florin Anghelina, Carmen Aurelia Mogoanta, Sorin-Mircea Ciolofan, Andreea Rusescu, Irina-Gabriela Ionita, Catalina Voiosu, Razvan Hainarosie

引用次数: 0

Evaluation of Transient Ischemic Stroke Cases Admitted to a Tertiary Hospital in Mehedinți County, South-West of Romania. 对罗马尼亚西南部 Mehedinți 县一家三级医院收治的短暂性缺血性中风病例进行评估。

Current health sciences journal Pub Date : 2023-07-01 Epub Date: 2023-09-30 DOI: 10.12865/CHSJ.49.03.04

Octavian Păun, Laurențiu Mogoantă

{"title":"Evaluation of Transient Ischemic Stroke Cases Admitted to a Tertiary Hospital in Mehedinți County, South-West of Romania.","authors":"Octavian Păun, Laurențiu Mogoantă","doi":"10.12865/CHSJ.49.03.04","DOIUrl":"10.12865/CHSJ.49.03.04","url":null,"abstract":"The transient ischemic attack (TIA) is a common cerebrovascular ischemic disease whose symptoms resolve within a maximum of 24 hours. The study carried out by us is a retrospective descriptive one, in which we sought to highlight the main characteristics of TIA in patients admitted to the Emergency Hospital in Turnu-Severin municipality in Mehedinți county, in the period 2016-2020, including a group of 53 patients, mainly from Mehedinți county. The analysis of the study group and the risk factors showed that TIA mainly affects the elderly, over 50 years old, with the highest incidence being recorded in the 60-80-year age groups, with an extremely low incidence under 40 years. Significant differences were found between the sexes and between the social environments, with women and people from the urban environment being more prone to suffer a TIA. Among the most important modifiable risk factors encountered in TIA patients included in the study, the following were highlighted: HTN, obesity and atherosclerosis. Knowing the modifiable factors and combating them can improve the prognosis of AIT.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10832879/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Obesity and Myocardial Infarction-The Place of Obesity Among Cardiovascular Risk Factors-Retrospective Study. 肥胖与心肌梗死--肥胖在心血管风险因素中的地位--回顾性研究。

Current health sciences journal Pub Date : 2023-07-01 Epub Date: 2023-09-30 DOI: 10.12865/CHSJ.49.03.11

Cristina-Elena Negroiu, Iulia Tudorascu, Cristiana Gianina Moise, Emilia Vinturis, Cristina Maria Bezna, Raluca Danoiu, Marinela Eugenia Gaman, Suzana Danoiu

{"title":"Obesity and Myocardial Infarction-The Place of Obesity Among Cardiovascular Risk Factors-Retrospective Study.","authors":"Cristina-Elena Negroiu, Iulia Tudorascu, Cristiana Gianina Moise, Emilia Vinturis, Cristina Maria Bezna, Raluca Danoiu, Marinela Eugenia Gaman, Suzana Danoiu","doi":"10.12865/CHSJ.49.03.11","DOIUrl":"10.12865/CHSJ.49.03.11","url":null,"abstract":"Since the 21st century, the leading cause of death is cardiovascular disease, with myocardial infarction being the most common. The incidence and prevalence of obesity has risen sharply in recent years, and it is commonly recognised as a cardiovascular risk factor among tobacco smoking, dyslipidemia (high LDL-C, high triglycerides, low HDL-C), hypertension, diabetes, age, gender, hereditary predisposition.Materials and methods: This study is a retrospective study conducted at the Craiova Emergency Clinical Hospital between October 2020 and January 2023. Enrolled patients are 60, 36 patients with ST-segment elevation myocardial infarction and 24 patients with non-ST-segment elevation acute myocardial infarction. The data was collected from the hospital's official database and then analyzed using Microsoft Excel and the Toolbar Data Analysis.Results: The mean age of the patients in the study was 62 years with a minimum of 34 years and a maximum of 84 years. 23(38.3%) of patients were smokers, 7(11.6%) were ex-smokers and 30(50%) were non-smokers. 49(81.6%) patients were hypertensive. 44(73%) had cholesterol greater than 200mg/dl. 54(90%) had LDL>100mg/dl, 18(30%) had HDL>45mg/gl, 24(40%) patients had serum TG>150mg/dl, 17(28%) were overweight and 13(22%) were obese, 30(50%) were normal weight. 18(30%) patients had type 2 diabetes.Conclusions: Among the cardiovascular risk factors in the patients studied, hypertension was the most common, followed by dyslipidemia, obesity, smoking, diabetes mellitus, and very rarely the use of drugs and anabolic substances.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10832884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PLGA-The Smart Biocompatible Polimer: Kinetic Degradation Studies and Active Principle Release. PLGA--智能生物相容性聚合物：动力学降解研究和活性成分释放。

Current health sciences journal Pub Date : 2023-07-01 Epub Date: 2023-09-30 DOI: 10.12865/CHSJ.49.03.15

Maria-Viorica Ciocîlteu, Rău Gabriela, Manuel Ovidiu Amzoiu, Denisa Constantina Amzoiu, Cătălina Gabriela Pisoschi, Beatrice Anne-Marie Poenariu

{"title":"PLGA-The Smart Biocompatible Polimer: Kinetic Degradation Studies and Active Principle Release.","authors":"Maria-Viorica Ciocîlteu, Rău Gabriela, Manuel Ovidiu Amzoiu, Denisa Constantina Amzoiu, Cătălina Gabriela Pisoschi, Beatrice Anne-Marie Poenariu","doi":"10.12865/CHSJ.49.03.15","DOIUrl":"10.12865/CHSJ.49.03.15","url":null,"abstract":"The aim of our research was the development of prolonged delivery systems for therapeutic agents with various properties (prevention and treatment of bone diseases, anti-neoplastic, anti-inflammatory, antioxidant) that would ensure sustained therapeutic levels of the active principle, above the minimum inhibitory concentration, without reaching toxic levels over a long period of time as alternatives to conventional routes of administration. PLGA (poly lactic-co-glycolic acid), a biodegradable and biocompatible synthetic polymer, FDA approved, with a 65:35 lactic acid (LA): glycolic acid (GA) copolymer ratio, was chosen as delivery system. Our studies have shown that in PBS it undergoes two simultaneous degradation processes, hydrolysis and autohydrolysis, degrading completely in about 40 days. The release of the active principle is determined by the diffusion from inside the polymer matrix to the outside, which occurs simultaneously with the erosion of the polymer, during 35 days.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10832882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute Toxicity by Salvia Officinalis: A Rare Cause of Intestinal Sub-Occlusion. 丹参的急性毒性：一种罕见的肠道下闭塞病因。

Current health sciences journal Pub Date : 2023-07-01 Epub Date: 2023-09-30 DOI: 10.12865/CHSJ.49.03.17

Alessandro Rapino, Giovanna Ceccuzzi, Benedetta Perna, Roberto DE Giorgio, Matteo Guarino

引用次数: 0

Hydrocephalus Resolution with Third Ventriculostomy with Floor Stenting: Technical Note and Literature Review. 第三脑室造口术加底部支架治疗脑积水：技术说明和文献综述。

Current health sciences journal Pub Date : 2023-07-01 Epub Date: 2023-09-30 DOI: 10.12865/CHSJ.49.03.19

José Ricardo Vanzin, Artur Eduardo Martio, Moema Nene Santos, Nerio Dutra Azambuja, Octávio Ruschel Karam, Luciano Bambini Manzato

{"title":"Hydrocephalus Resolution with Third Ventriculostomy with Floor Stenting: Technical Note and Literature Review.","authors":"José Ricardo Vanzin, Artur Eduardo Martio, Moema Nene Santos, Nerio Dutra Azambuja, Octávio Ruschel Karam, Luciano Bambini Manzato","doi":"10.12865/CHSJ.49.03.19","DOIUrl":"10.12865/CHSJ.49.03.19","url":null,"abstract":"Introduction: The management of refractory obstructive hydrocephalus is a paramount neurosurgical challenge. The endoscopic third ventriculostomy (ETV) has been accepted as the procedure of choice for obstructive hydrocephalus, depending on the presence of certain risk factors, such as intracranial infections, young age, previous shunt failure and distorted anatomy of the ventricular floor, that predispose occlusion or obstruction of the CSF outflow through the stoma.Case report: A 20-year-old man with obstructive hydrocephalus due to primary aqueductal stenosis performed several neurosurgical procedures, including two previous ETV, without long term resolution. We performed another ETV, with stent placement at the stoma to prevent occlusion. After 25 months of asymptomatic follow-up, the patient presented with an enlarged fourth ventricle, and a new neuroendoscopic procedure showed a patent stoma and a well-placed stent.Discussion: Stent placement on the third ventricular floor was already reported 19 times in the literature. Its success rate is about 94,7%, and complications happened in 2 cases, with functional impaired in only one of them.Conclusion: Third ventriculostomy with floor stenting proved to be an effective procedure in our case of complex hydrocephalus. It is a viable option in cases where there is a greater chance of stoma occlusion.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10832873/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genomic Profiling - A Need for Clinical Decision? -Case Reports. 基因组剖析--临床决策的需要？-案例报告。

Current health sciences journal Pub Date : 2023-07-01 Epub Date: 2023-09-30 DOI: 10.12865/CHSJ.49.03.22

Ana-Maria Ciurea, Michael Schenker, Cristina Mihaela Ciofiac, Liliana Streba, Ramona Schenker, Costin Teodor Streba

{"title":"Genomic Profiling - A Need for Clinical Decision? -Case Reports.","authors":"Ana-Maria Ciurea, Michael Schenker, Cristina Mihaela Ciofiac, Liliana Streba, Ramona Schenker, Costin Teodor Streba","doi":"10.12865/CHSJ.49.03.22","DOIUrl":"10.12865/CHSJ.49.03.22","url":null,"abstract":"Cancer is still an important health issue worldwide due to increased incidence and mortality. Personalized medicine is the future of cancer treatment. Development in technology improved technical skills in DNA/RNA sequencing. NGS technology in solid-tumor samples can describe DNA or RNA analysis by including the entire genome to detect clinical relevant mutations. Genetic results may be considered having a dynamic impact because of heterogenous molecular alterations depending of time and treatment influence. We conducted a retrospective study of all NGS tests made in the last five years for the patients from 'Sf. Nectarie' Oncology Center, Craiova, Romania. We selected three relevant clinical cases where NGS analysis was performed and the results changed the perspective of the clinical decision. Our aim is to evaluate the importance of NGS results in clinical approach. Although medicine known an important development during the last decades, only a few patients can benefit of advanced personalized treatments. It is still hard to identify the alterations or gene mutations because of genetic tests are not easily available and only a small proportion of patients carries genetic alterations.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10832885/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Zinc-Boron Complex-Based Dietary Supplements for Longevity and Healthy Life. 基于锌硼复合物的膳食补充剂，促进长寿和健康生活。

Current health sciences journal Pub Date : 2023-07-01 Epub Date: 2023-09-30 DOI: 10.12865/CHSJ.49.03.10

Andrei Biţă, Ion Romulus Scorei, Tudor Adrian Bălşeanu, Gabriela Rău, Maria Viorica Ciocîlteu, George Dan Mogoşanu

引用次数: 0

Retrospective Study of a Patient with Multiple de Novo Skin Tumor Formations. 对一名多发性皮肤肿瘤患者的回顾性研究

Current health sciences journal Pub Date : 2023-07-01 Epub Date: 2023-09-30 DOI: 10.12865/CHSJ.49.03.18

Radu-Florin Fruntealată, Tudor Adrian Balseanu, Oliviu Nica, Alina Andreea Negrila, Ilaria Lorena Petrovici, Elena Alexandra Marinescu, George-Alin Stoica, Maria Stoica, Ana-Maria Ciurea, Marius-Eugen Ciurea

引用次数: 0

Considerations on Patients' Quality of Life Following Hand and Forearm Trauma in the Oltenia Region. 奥尔特尼亚地区手部和前臂创伤后患者生活质量的思考。

Current health sciences journal Pub Date : 2023-04-01 Epub Date: 2023-06-30 DOI: 10.12865/CHSJ.49.02.273

Alexandra Florinda Ghițan, Victor Gheorman, Ion Udriștoiu, Marius Eugen Ciurea

{"title":"Considerations on Patients' Quality of Life Following Hand and Forearm Trauma in the Oltenia Region.","authors":"Alexandra Florinda Ghițan, Victor Gheorman, Ion Udriștoiu, Marius Eugen Ciurea","doi":"10.12865/CHSJ.49.02.273","DOIUrl":"10.12865/CHSJ.49.02.273","url":null,"abstract":"Hand and forearm trauma is a significant public health concern that has notable physical, psychological, and socioeconomic implications. Understanding the variations in occurrence and characteristics of injuries across different regions is crucial for effective implementation of preventive measures, management strategies, and resource allocation. The study involved 86 cases, with a range of ages from 18 to 70 years old. The participant group consisted of 11 females and 75 males. A series of clinical parameters were analyzed, including gender, age, environment, and cause of trauma. The study requested that participants provide information regarding if they reintegrated into their professional lives and complete the WHOQOL-BREF assessment, which is a tool used to evaluate quality of life. The current investigation has determined that the primary etiologies for hand and forearm injuries are crush and sharp cuts. The results of the investigation indicate a noteworthy association among Age and Cause, Gender and Age, Age and Professional reintegration, as well as between WHOQOL-BREF scores and different parameters. The procurement of epidemiological data plays a crucial role in broadening our comprehension of acute hand and forearm injuries in the Oltenia region.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/37/59/CHSJ-49-02-273.PMC10541057.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41124441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0