Contraception and reproductive medicine最新文献

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Ovario-protective effect of intra-ovarian injection of platelet rich plasma (PRP) after laparoscopic cystectomy of ovarian endometrioma: a randomized control trial. 腹腔镜卵巢子宫内膜瘤切除术后卵巢内注射富血小板血浆(PRP)对卵巢的保护作用:一项随机对照试验。
IF 1.9
Contraception and reproductive medicine Pub Date : 2025-10-01 DOI: 10.1186/s40834-025-00377-0
Samaneh Rokhgireh, Fereshteh Rahimi, Neda Eslahi, Roya Derakhshan, Arash Mohazzab
{"title":"Ovario-protective effect of intra-ovarian injection of platelet rich plasma (PRP) after laparoscopic cystectomy of ovarian endometrioma: a randomized control trial.","authors":"Samaneh Rokhgireh, Fereshteh Rahimi, Neda Eslahi, Roya Derakhshan, Arash Mohazzab","doi":"10.1186/s40834-025-00377-0","DOIUrl":"10.1186/s40834-025-00377-0","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the effectiveness of Platelet-Rich Plasma (PRP) in preserving ovarian reserve in patients with endometriosis who underwent laparoscopic cystectomy.</p><p><strong>Method: </strong>A randomized, parallel, open-label phase II clinical trial was conducted. A total of 38 eligible women aged 20 to 35 years with ovarian endometrioma, candidates for laparoscopic ovarian cystectomy, were randomly assigned to either the PRP group (n = 20) or the control group (n = 18). The PRP group received an intra-ovarian injection of 2-4 cc of PRP immediately after cystectomy, while the control group underwent cystectomy without additional intervention. The primary outcome was the change in serum anti-Müllerian hormone (AMH) levels six months post-intervention. The secondary outcome was the antral follicle count (AFC) six months post-intervention. Short-term adverse effects were monitored within the first 48 h after the procedure.</p><p><strong>Results: </strong>The PRP group showed a negligible change in AMH levels (mean difference 0.05, 95% CI: -0.17 to 0.26), while the control group exhibited a significant decline (mean difference - 0.24, 95% CI: -0.5 to 0.12). The adjusted mean difference between the groups was - 0.308 (-0.626 to -0.01), tending toward statistical significance (P = 0.057). No significant differences in AFC were observed between the groups, and no short-term adverse events were reported.</p><p><strong>Conclusions: </strong>This phase II exploratory trial found a near-significant trend toward preservation of AMH levels with intra-ovarian PRP injection after endometrioma surgery. While these findings are not definitive, they support the feasibility and safety of the approach and warrant further evaluation in larger, controlled trials.</p><p><strong>Trial registration: </strong>The study was prospectively registered in the Iranian Registry of Clinical Trials under the number IRCT20191123045476N3 on December 1, 2021 ( https://irct.behdasht.gov.ir/trial/58688 ).</p>","PeriodicalId":93956,"journal":{"name":"Contraception and reproductive medicine","volume":"10 1","pages":"66"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Piloting measures of provider-imposed contraceptive coercion among reproductive-aged contraceptive users in Kisumu, Kenya: a cross-sectional, population-based study. 在肯尼亚基苏木的育龄避孕药具使用者中试行提供者强制避孕措施:一项基于人口的横断面研究。
IF 1.9
Contraception and reproductive medicine Pub Date : 2025-10-01 DOI: 10.1186/s40834-025-00394-z
Brooke W Bullington, Stephanie Chung, Dickens Otieno Onyango, Leigh Senderowicz, Emilia Goland, Claire W Rothschild, Abigael Mwanyiro, Ben Wekesa, Brian Frizzelle, Ginger Golub, Katherine Tumlinson
{"title":"Piloting measures of provider-imposed contraceptive coercion among reproductive-aged contraceptive users in Kisumu, Kenya: a cross-sectional, population-based study.","authors":"Brooke W Bullington, Stephanie Chung, Dickens Otieno Onyango, Leigh Senderowicz, Emilia Goland, Claire W Rothschild, Abigael Mwanyiro, Ben Wekesa, Brian Frizzelle, Ginger Golub, Katherine Tumlinson","doi":"10.1186/s40834-025-00394-z","DOIUrl":"10.1186/s40834-025-00394-z","url":null,"abstract":"<p><strong>Introduction: </strong>Little research has focused on measuring free contraceptive choice, or whether individuals can make decisions about contraception without barriers or coercion. To advance measurement, we pilot survey questions focused on experiences of provider-imposed contraceptive coercion using population-based data collected among contraceptive users in Kisumu, Kenya.</p><p><strong>Methods: </strong>We describe the percentage of women who reported provider-imposed coercion-related outcomes. We then examine demographic and facility-level correlates of feeling pressured or unable to say no to contraception and compare the extent that measures of feeling pressured and unable to say no to contraception overlap using 2 × 2 tables and Cohen's Kappa Statistic.</p><p><strong>Results: </strong>The percentage of participants who reported provider-imposed coercion ranged by question from 1% to 57%. There were no associations between demographic or facility characteristics, including age, marital status, parity, and facility type (public or private), and either reporting feeling pressured or reporting feeling unable to say no to using contraception. There was no agreement between measures of feeling pressured and unable to say no to contraception (Kappa statistic - 0.11).</p><p><strong>Conclusions: </strong>Our findings suggest that many women in Kisumu report experiencing some form of provider-imposed contraceptive coercion, though the proportion who report such experiences varies based on survey question. Further research is needed to improve reliable measurement of free contraceptive choice.</p>","PeriodicalId":93956,"journal":{"name":"Contraception and reproductive medicine","volume":"10 1","pages":"64"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sociodemographic factors associated with modern contraceptive use in Japan: an analysis of national survey data. 与日本现代避孕药具使用相关的社会人口因素:国家调查数据分析。
IF 1.9
Contraception and reproductive medicine Pub Date : 2025-10-01 DOI: 10.1186/s40834-025-00391-2
Tasuku Okui
{"title":"Sociodemographic factors associated with modern contraceptive use in Japan: an analysis of national survey data.","authors":"Tasuku Okui","doi":"10.1186/s40834-025-00391-2","DOIUrl":"10.1186/s40834-025-00391-2","url":null,"abstract":"<p><strong>Background: </strong>Few studies have examined the sociodemographic characteristics associated with modern contraceptive use in Japan. This study investigated these associations using data from the National Fertility Survey.</p><p><strong>Methods: </strong>Data were retrieved from the National Fertility Survey targeting unmarried individuals and married women in Japan. The analysis included unmarried individuals with sexual experience and sexually active married women intending to stop or space childbirths. Modern contraceptive use was examined in relation to sociodemographic characteristics, including age group, number of children, educational attainment, employment status, and income, among unmarried men and women as well as married women. Modified Poisson regression models were employed for the analysis.</p><p><strong>Results: </strong>Data from 4,874 unmarried individuals and 1,533 married women were used in the analysis. Among both groups, younger age was associated with a higher prevalence of modern contraceptive use. Among unmarried individuals, having one or two children was significantly negatively associated with modern contraceptive use. Conversely, among married women, having multiple children was positively associated with modern contraceptive use. Additionally, a significant negative association was found between being a junior high or high school graduate and modern contraceptive use among unmarried men. Similarly, a significant negative association was observed among married women who were high school graduates. Conversely, modern contraceptive use was significantly positively associated with being an unemployed wife.</p><p><strong>Conclusions: </strong>Modern contraceptive use in Japan was associated with various sociodemographic characteristics, including the number of children, educational attainment, and employment status.</p>","PeriodicalId":93956,"journal":{"name":"Contraception and reproductive medicine","volume":"10 1","pages":"65"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Too far to follow up: associations between residential distance and social vulnerability on immediate postpartum contraceptive uptake. 太远,无法跟进:居住距离与产后立即服用避孕药的社会脆弱性之间的关系。
IF 1.9
Contraception and reproductive medicine Pub Date : 2025-10-01 DOI: 10.1186/s40834-025-00390-3
L O Barbee, Q A Class
{"title":"Too far to follow up: associations between residential distance and social vulnerability on immediate postpartum contraceptive uptake.","authors":"L O Barbee, Q A Class","doi":"10.1186/s40834-025-00390-3","DOIUrl":"10.1186/s40834-025-00390-3","url":null,"abstract":"<p><strong>Background: </strong>Postpartum contraception plays a vital role in extending interpregnancy intervals and reducing adverse maternal and neonatal outcomes. However, patients at elevated risk due to geographic and social barriers may experience disruptions in postpartum care. We examine associations between residential distance to the delivery hospital and social determinants of health (SDoH) with contraception uptake at delivery discharge.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study of live births born at 22.0 gestational age and greater at a single urban academic center from March 2020 to March 2022. Demographic, obstetric, and SDoH data were extracted from electronic medical records. Contraceptive method recorded for all births as part of the delivery discharge note was manually reviewed classified into long-acting reversible contraception (LARC) or non-LARC methods. Univariate analyses were used to compare characteristics across groups living within 10.0 miles and those living 10.1 miles or further from the hospital. Logistic regression was used to identify predictors of LARC uptake.</p><p><strong>Results: </strong>A total of 3,644 births were included; 54.6% of patients were Black, 30.3% Hispanic, and 73.7% utilized public insurance. A total of 74.2% of patients resided within 10.0 miles of the delivery hospital. Patients living farther away were more likely to face transportation barriers, lower educational attainment, and higher SDoH personal risk scores. Overall, 18.6% living closer and 22.3% living further from the delivery hospital received LARC at discharge [X<sup>2</sup> (2) = 7.45, p < .05]. After adjustment for race, ethnicity, insurance, maternal age, partnership status, and a combined risk factor that assigned a positive binary indicator if the neonate was delivered via cesarean section, had a NICU stay, and/or, the maternal length of hospital stay was greater than 3 days, odds for LARC uptake at delivery discharge was elevated for those living further from the hospital as compared to those living closer to the delivery hospital (OR = 1.20, 95% CI = 1.01-1.43). Those with high personal SDoH risk also had significantly higher odds of LARC uptake at discharge (OR = 1.24, 95% CI 1.02-1.50) as compared to those without SDoH personal risk noted.</p><p><strong>Conclusion: </strong>Several factors remained associated with LARC uptake at delivery discharge including residential distance, SDoH, and insurance. Our findings support the importance of inpatient contraceptive counseling and provision, particularly for socially vulnerable populations.</p>","PeriodicalId":93956,"journal":{"name":"Contraception and reproductive medicine","volume":"10 1","pages":"67"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Usage of contraception among the married women in India, 2019-21: a cross-sectional study. 2019-21年印度已婚妇女避孕措施使用情况:一项横断面研究
IF 1.9
Contraception and reproductive medicine Pub Date : 2025-09-30 DOI: 10.1186/s40834-025-00375-2
Chander Shekhar, Harihar Sahoo, Labhita Das
{"title":"Usage of contraception among the married women in India, 2019-21: a cross-sectional study.","authors":"Chander Shekhar, Harihar Sahoo, Labhita Das","doi":"10.1186/s40834-025-00375-2","DOIUrl":"10.1186/s40834-025-00375-2","url":null,"abstract":"<p><strong>Background: </strong>Contraceptive use plays a significant role in reducing fertility and improving maternal and child health. Understanding utilization patterns and preferences is essential for addressing unmet needs in family planning among married women in India.</p><p><strong>Objective: </strong>This study aims to analyse the usage of contraceptive methods among the married women aged 15-49 years in India, and to identify the factors associated with contraceptive uptake.</p><p><strong>Methods: </strong>Cross-sectional data from the fifth round of the National Family Health Survey, (2019-21) were used for this analysis. NFHS is a periodic cross-sectional survey conducted using a multistage household sampling design in India. The total sample consisted of 512,408 women aged 15-49 years currently in a marital union. Cross-tabulation was conducted to evaluate the levels of contraceptive use, and logistic regression was utilized to identify factors associated with contraceptive uptake. The entire analysis was performed using the STATA 17.0 statistical software.</p><p><strong>Results: </strong>Contraceptive usage among married women has increased from 53.5% in NFHS-4 (2015-16) to 65.7% in NFHS-5 (2019-21). The likelihood of contraception usage among the married women in India is significantly influenced by the factors like age of the women, educational attainment, desire for children, caste, religion, wealth index, exposure to mass media and place of residence.</p><p><strong>Conclusion: </strong>Despite advancements in reproductive health, contraceptive uptake among married women in India remains insufficient. To address this, interventions should prioritize the provision of diverse contraceptive options, along with comprehensive counselling, to emphasize the benefits and proper use of these methods. Addressing socio-demographic disparities is essential for improving equitable access to family planning services.</p>","PeriodicalId":93956,"journal":{"name":"Contraception and reproductive medicine","volume":"10 1","pages":"60"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating long-acting reversible contraceptive service quality at Manna Woreda health posts, Southwest Ethiopia: a mixed method study. 评估埃塞俄比亚西南部Manna wooreda卫生站的长效可逆避孕服务质量:一项混合方法研究。
IF 1.9
Contraception and reproductive medicine Pub Date : 2025-09-30 DOI: 10.1186/s40834-025-00359-2
Wada Delelegn, Lidet Tadele, Muluemebet Abera, Awoke Masrie, Bezawit Birhanu, Yisalemush Asefa
{"title":"Evaluating long-acting reversible contraceptive service quality at Manna Woreda health posts, Southwest Ethiopia: a mixed method study.","authors":"Wada Delelegn, Lidet Tadele, Muluemebet Abera, Awoke Masrie, Bezawit Birhanu, Yisalemush Asefa","doi":"10.1186/s40834-025-00359-2","DOIUrl":"10.1186/s40834-025-00359-2","url":null,"abstract":"<p><strong>Background: </strong>Long-acting reversible contraception is a key strategy for preventing unintended pregnancies, unbalanced human population growth, and unsafe abortions. There is limited evidence on the quality of long-acting reversible contraceptive services in Ethiopia, particularly in the study area. Therefore, this study aimed to evaluate the quality of long-acting reversible contraception services in the health Posts of Manna Woreda, Southwest Ethiopia.</p><p><strong>Method: </strong>A case study evaluation design using a mixed method was employed from May 9 to June 25, 2021. Eight health posts were purposively selected from the 26 health posts in Woreda. Client exit interviews, direct observation, 3-month document review, resource inventories, and key informant interviews were also conducted. The quantitative data were entered into Epi-Data version 4.6 and exported to SPSS version 24 for analysis. Qualitative data were transcribed, translated, coded, and analyzed using thematic analysis. The overall quality of program implementation was measured based on predetermined judgmental criteria.</p><p><strong>Results: </strong>The overall quality of long-acting reversible contraceptive services was 66.8%, with availability at 77.15%, provider compliance with national guidelines at 53.1%, and client satisfaction at 70%. Notable gaps included poor information provision during consultation, absence of supportive supervision, guidelines, and lack of infrastructure and information education materials. Additionally, there were gaps in the provision of services according to national guidelines.</p><p><strong>Conclusion: </strong>The overall quality status of long-acting reversible contraception services was judged to be good, although service providers' compliance with the national guidelines was fair, and client satisfaction was judged to be good. Shortage of infrastructure, such as electricity, water, guidelines, and information education communication aids. Therefore, the Woreda Health Office should provide guidelines, equipment, and regular supportive supervision to improve the service quality.</p>","PeriodicalId":93956,"journal":{"name":"Contraception and reproductive medicine","volume":"10 1","pages":"61"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of abnormal bleeding in etonogestrel-releasing implant users: quo vadis? An exploratory study on the attitudes of a cohort of Italian gynaecologists and review of the literature. 依托孕酮释放植入物使用者异常出血的处理:现状?对一群意大利妇科医生的态度的探索性研究和文献综述。
IF 1.9
Contraception and reproductive medicine Pub Date : 2025-09-30 DOI: 10.1186/s40834-025-00399-8
Arianna Siconolfi, Martino Azzi, Alessandra Lami, Elena Sanna, Renato Seracchioli, Maria Cristina Meriggiola
{"title":"Management of abnormal bleeding in etonogestrel-releasing implant users: quo vadis? An exploratory study on the attitudes of a cohort of Italian gynaecologists and review of the literature.","authors":"Arianna Siconolfi, Martino Azzi, Alessandra Lami, Elena Sanna, Renato Seracchioli, Maria Cristina Meriggiola","doi":"10.1186/s40834-025-00399-8","DOIUrl":"10.1186/s40834-025-00399-8","url":null,"abstract":"<p><strong>Introduction: </strong>Long-acting reversible contraceptives (LARCs) are increasingly gaining popularity due to their high efficacy and ease of use compared to short-acting reversible contraceptives (SARCs). Among available LARCs, the etonogestrel (ENG) subdermal implant represents a particularly effective contraceptive method. However, many patients request early removal of the device due to the persistence of unfavourable bleeding patterns.</p><p><strong>Methods: </strong>We developed a short, multiple-choice ad hoc questionnaire distributed online from October 2024 to March 2025 to investigate the attitude of Italian gynaecologists towards medical treatment of unfavourable bleeding in women using the ENG-releasing implant. A total of 141 physicians responded reporting their first- and second-line treatments for patients with and without a contraindication to combined oral contraceptives (COC). We discuss the results of our survey in the light of the existing literature, through a systematic review including studies evaluating medical treatments in ENG implant users experiencing troublesome bleeding.</p><p><strong>Results and conclusion: </strong>The results of our survey and the review of the literature highlight the diverse, sparse, and sometimes confused approaches to unfavourable bleeding in ENG implant users. In our survey, up to 19% of practitioners indicated they would not know what to do in different case scenarios. In order to help gynaecologists gain greater confidence in managing this symptom, large randomised controlled trials (RCTs) with long-term follow-up on which clinical guidelines and standardized training programs can be based, are needed.</p>","PeriodicalId":93956,"journal":{"name":"Contraception and reproductive medicine","volume":"10 1","pages":"62"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distribution and variations of anti-müllerian hormone (AMH) levels among poor-responder women: a multiple linear regression analysis. 抗<s:1>勒氏杆菌激素(AMH)水平在不良反应妇女中的分布和变化:多元线性回归分析。
IF 1.9
Contraception and reproductive medicine Pub Date : 2025-09-30 DOI: 10.1186/s40834-025-00402-2
Parvin Hakimi, Fatemeh Tabatabaei, Roya Ghaffari, Fatemeh Kazemi Namin, Hosein Azizi, Roya Kabodmehri, Mahshid Alborzi
{"title":"Distribution and variations of anti-müllerian hormone (AMH) levels among poor-responder women: a multiple linear regression analysis.","authors":"Parvin Hakimi, Fatemeh Tabatabaei, Roya Ghaffari, Fatemeh Kazemi Namin, Hosein Azizi, Roya Kabodmehri, Mahshid Alborzi","doi":"10.1186/s40834-025-00402-2","DOIUrl":"10.1186/s40834-025-00402-2","url":null,"abstract":"<p><strong>Background: </strong>Anti-Mullerian hormone (AMH) is an indicator of a woman's ovarian reserve or the number of follicles remaining in her ovaries. While the level of AMH is typically low among poor responders, there is significant variation in its levels among poor responders.</p><p><strong>Objective: </strong>This study aimed to investigate the AMH level in poor-responder women and examine its association with nutrition, lifestyle, and reproductive characteristics.</p><p><strong>Methods: </strong>A total of 119 infertile women with poor-responder were randomly selected from the infertility clinic of Al-Zahra Hospital, Tabriz, in 2022. Clinical, lifestyle, and reproductive characteristics were measured using valid instruments and para-clinical tests. Multiple linear regression analysis was carried out to estimate the variations of AMH level among poor-responder women.</p><p><strong>Results: </strong>The average age of the participants was 36.6, and a significant negative correlation was found between advanced age and AMH level (r = -0.35, P = 0.001). In the final analysis, after adjusting for potential confounders using multiple linear regression, each unit increase in age, passive smoking, the cold season, poor or no vegetable consumption, and poor physical activity resulted in a decrease in AMH level by -0.162, -0.123, -0.321, -0.199, and - 0.212, respectively.</p><p><strong>Conclusion: </strong>Findings indicated that lifestyle and nutrition are correlated with AMH levels in infertile women with poor responder. Promoting a healthy lifestyle can improve ovarian reserve in these women with with low level of AMH.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":93956,"journal":{"name":"Contraception and reproductive medicine","volume":"10 1","pages":"63"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicting pregnancy outcomes in IVF cycles: a systematic review and diagnostic meta- analysis of artificial intelligence in embryo assessment. 预测IVF周期的妊娠结局:人工智能在胚胎评估中的系统回顾和诊断荟萃分析。
IF 1.9
Contraception and reproductive medicine Pub Date : 2025-09-28 DOI: 10.1186/s40834-025-00400-4
Ataei Mina, Masumeh Younesi, Tahereh Doohandeh, Soheila Darzi, Negar Ajabi Ardehjani, Samaneh Sheibani, Hossein Hosseinirad, Rohollah Valizadeh
{"title":"Predicting pregnancy outcomes in IVF cycles: a systematic review and diagnostic meta- analysis of artificial intelligence in embryo assessment.","authors":"Ataei Mina, Masumeh Younesi, Tahereh Doohandeh, Soheila Darzi, Negar Ajabi Ardehjani, Samaneh Sheibani, Hossein Hosseinirad, Rohollah Valizadeh","doi":"10.1186/s40834-025-00400-4","DOIUrl":"10.1186/s40834-025-00400-4","url":null,"abstract":"<p><strong>Introduction: </strong>Embryo selection remains a key challenge in in vitro fertilization (IVF), as many morphologically \"normal\" embryos fail to implant. Artificial intelligence (AI) offers a promising tool for improving embryo assessment by providing more objective and accurate predictions of pregnancy outcomes. This study aims to systematically review and conduct a diagnostic meta-analysis to evaluate the effectiveness of AI-based tools in embryo selection for predicting pregnancy outcomes in IVF.</p><p><strong>Methods: </strong>We conducted a systematic review following PRISMA guidelines, searching Web of Science, Scopus, and PubMed. Original research articles evaluating AI's diagnostic accuracy in embryo selection were included, while duplicates, non-peer-reviewed papers, abstracts, and conference proceedings were excluded. Data on sample sizes, AI tools, and diagnostic metrics were extracted, with quality assessed using the QUADAS-2 tool.</p><p><strong>Results: </strong>AI-based embryo selection methods showed strong diagnostic performance, with pooled sensitivity of 0.69 and specificity of 0.62 in predicting implantation success. The positive likelihood ratio was 1.84 and the negative likelihood ratio was 0.5. The area under the curve reached 0.7, indicating high overall accuracy. The Life Whisperer AI model achieved 64.3% accuracy in predicting clinical pregnancy, while the FiTTE system, which integrates blastocyst images with clinical data, improved prediction accuracy to 65.2% with an AUC of 0.7.</p><p><strong>Conclusion: </strong>AI offers a promising advancement in embryo selection for IVF, with the potential to enhance clinical outcomes and improve decision-making. Future studies should focus on refining these models to achieve the ultimate goal of a healthy live birth by developing more sophisticated algorithms and validating them with larger, diverse datasets.</p>","PeriodicalId":93956,"journal":{"name":"Contraception and reproductive medicine","volume":"10 1","pages":"59"},"PeriodicalIF":1.9,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bridging gaps in maternity care for women with disabilities: a scoping review of access and utilisation in sub-Saharan Africa adopting the WHO health systems framework. 缩小残疾妇女孕产妇保健方面的差距:采用世卫组织卫生系统框架对撒哈拉以南非洲获取和利用情况进行范围审查。
IF 1.9
Contraception and reproductive medicine Pub Date : 2025-09-25 DOI: 10.1186/s40834-025-00395-y
Obasanjo Bolarinwa, Aliu Mohammed
{"title":"Bridging gaps in maternity care for women with disabilities: a scoping review of access and utilisation in sub-Saharan Africa adopting the WHO health systems framework.","authors":"Obasanjo Bolarinwa, Aliu Mohammed","doi":"10.1186/s40834-025-00395-y","DOIUrl":"10.1186/s40834-025-00395-y","url":null,"abstract":"<p><strong>Background: </strong>Women with disabilities face higher risks of maternal morbidity and mortality, particularly in low- and middle-income countries like sub-Saharan Africa (SSA). Barriers such as socio-cultural stigma, health facility inaccessibility, and lack of supportive healthcare contribute to their limited access to maternity services, exacerbating their vulnerability. Despite significant research on maternal health in SSA, studies focusing on women with disabilities remain scarce, and current healthcare services often fail to accommodate their needs. This scoping review explores barriers to maternity care accessibility among women with disabilities in SSA, highlighting gaps in research necessary for developing interventions that align with global health goals, such as reducing maternal mortality by 2030.</p><p><strong>Methods: </strong>This current scoping review was informed by the methodological framework proposed by Arksey and O'Malley. Exploratory searches were conducted in JSTOR, PubMed, PsycINFO, African Journals Online, and Web of Science, etc., to identify studies conducted in SSA that focused on access, utilisation, and barriers to maternity services such as antenatal care (ANC) visits, facility delivery, and postnatal care visits among women with disabilities in SSA since the introduction of the sustainable development goals (SDGs). Twenty-two studies were included, spanning from June 1st 2016 to 30th May 2024.</p><p><strong>Results: </strong>Of the 22 eligible studies out of 416 identified studies published between 2016 and 2024, 20 were conducted across eight countries in SSA. Eight studies employed quantitative methods, 12 used qualitative approaches, and two used mixed-methods analysis. These studies focused on all or either of the maternal health services measured in this study, which include antenatal care (ANC), facility delivery, and postnatal care (PNC) among women with disabilities. Findings indicate that, despite a strong desire for ANC, physical impairments, mobility issues, and unsupportive infrastructure hinder access. Although facility deliveries were high, support gaps and negative provider attitudes were common. The WHO health system framework categorisation shows that more barriers are within the service delivery and health workforce domains.</p><p><strong>Conclusion: </strong>The review found limited studies on access to and utilisation of ANC, facility delivery, and PNC for women with disabilities in SSA. This gap restricts understanding of the issue and hampers interventions, increasing risks to maternal and child health. Urgent research and interventions are needed to address equity challenges in these services for disabled women in SSA.</p>","PeriodicalId":93956,"journal":{"name":"Contraception and reproductive medicine","volume":"10 1","pages":"58"},"PeriodicalIF":1.9,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12465681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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