Biological research for nursing最新文献_第5页

Prenatal Gut Microbiota Predicts Temperament in Offspring at 1-2 Years. 产前肠道微生物群可预测1-2岁后代的性情

Biological research for nursing Pub Date : 2024-10-01 Epub Date: 2024-06-12 DOI: 10.1177/10998004241260894

Yanan Cao, Xu Zhang, Qianping Zhang, Xiaoxiao Fan, Tianzi Zang, Jinbing Bai, Yuanyuan Wu, Wenjie Zhou, Yanqun Liu

{"title":"Prenatal Gut Microbiota Predicts Temperament in Offspring at 1-2 Years.","authors":"Yanan Cao, Xu Zhang, Qianping Zhang, Xiaoxiao Fan, Tianzi Zang, Jinbing Bai, Yuanyuan Wu, Wenjie Zhou, Yanqun Liu","doi":"10.1177/10998004241260894","DOIUrl":"10.1177/10998004241260894","url":null,"abstract":"The purpose of this study was to explore whether prenatal gut microbiota (GM) and its functions predict the development of offspring temperament. A total of 53 mothers with a 1-year-old child and 41 mothers with a 2-year-old child were included in this study using a mother-infant cohort from central China. Maternal fecal samples collected during the third trimester were analyzed using 16S rRNA V3-V4 gene sequences. Temperament of the child was measured by self-reported data according to the primary caregiver. The effects of GM in mothers on offspring's temperament were evaluated using multiple linear regression models. The results demonstrated that the alpha diversity index Simpson of prenatal GM was positively associated with the activity level of offspring at 1 year (adj. P = .036). Bifidobacterium was positively associated with high-intensity pleasure characteristics of offspring at 1 year (adj. P = .031). Comparatively, the presence of Bifidobacterium found in the prenatal microbiome was associated with low-intensity pleasure characteristics in offspring at 2 years (adj. P = .031). There were many significant associations noted among the functional pathways of prenatal GM and temperament of offspring at 2 years. Our findings support the maternal-fetal GM axis in the setting of fetal-placental development with subsequent postnatal neurocognitive developmental outcomes, and suggest that early childhood temperament is in part associated with specific GM in the prenatal setting.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"569-583"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141307576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Virtual Reality Glasses Application on Pain, Anxiety, and Patient Satisfaction During a Transrectal Prostate Biopsy: A Randomized Controlled Trial. 虚拟现实眼镜应用对经直肠前列腺活检过程中疼痛、焦虑和患者满意度的影响：随机对照试验。

Biological research for nursing Pub Date : 2024-10-01 Epub Date: 2024-02-28 DOI: 10.1177/10998004241236154

Rumeysa Lale Toraman, Vesile Eskici Ilgin

{"title":"Effect of Virtual Reality Glasses Application on Pain, Anxiety, and Patient Satisfaction During a Transrectal Prostate Biopsy: A Randomized Controlled Trial.","authors":"Rumeysa Lale Toraman, Vesile Eskici Ilgin","doi":"10.1177/10998004241236154","DOIUrl":"10.1177/10998004241236154","url":null,"abstract":"Background: This study aims to determine the effect of virtual reality glasses application on pain, anxiety, and patient satisfaction during a transrectal prostate biopsy.Materials and methods: The study was conducted with pre-tests, post-tests, and a control group, using a randomized controlled experimental research design. A total of 70 patients (35 in the intervention group and 35 in the control group) were included in the study. The intervention group watched a video with virtual reality glasses during the biopsy process. A Descriptive Information Form, State-Trait Anxiety Inventory (STAI-I, STAI-II), Scale of Patient Perception of Hospital Experience with Nursing Care (PPHEN), and Visual Analog Scale for Pain (VAS) were used for data collection. To evaluate the data, numbers, percentages, mean, standard deviation, chi-square, paired sample t test, independent samples t test, regression analysis, and Cronbach's alpha Reliability Coefficient were used.Results: There was no significant difference between the groups in terms of descriptive and clinical characteristics (p > .05). The mean VAS and STAI post-test scores of the patients in the intervention group were lower than the control group, and the difference between them was statistically significant (p < .05). The mean PPHEN post-test scores of the patients in the intervention group were significantly higher than those in the control group (p < .05).Conclusion: The application of virtual reality glasses during a transrectal prostate biopsy significantly reduced the level of pain and anxiety and increased patient satisfaction.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"485-497"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139992082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Gut Microbiome and Symptom Burden After Kidney Transplantation: An Overview and Research Opportunities. 肠道微生物组与肾移植后的症状负担：概述与研究机会。

Biological research for nursing Pub Date : 2024-10-01 Epub Date: 2024-06-05 DOI: 10.1177/10998004241256031

Mark B Lockwood, Choa Sung, Suzanne A Alvernaz, John R Lee, Jennifer L Chin, Mehdi Nayebpour, Beatriz Peñalver Bernabé, Lisa M Tussing-Humphreys, Hongjin Li, Mario Spaggiari, Alessandro Martinino, Chang G Park, George E Chlipala, Ardith Z Doorenbos, Stefan J Green

{"title":"The Gut Microbiome and Symptom Burden After Kidney Transplantation: An Overview and Research Opportunities.","authors":"Mark B Lockwood, Choa Sung, Suzanne A Alvernaz, John R Lee, Jennifer L Chin, Mehdi Nayebpour, Beatriz Peñalver Bernabé, Lisa M Tussing-Humphreys, Hongjin Li, Mario Spaggiari, Alessandro Martinino, Chang G Park, George E Chlipala, Ardith Z Doorenbos, Stefan J Green","doi":"10.1177/10998004241256031","DOIUrl":"10.1177/10998004241256031","url":null,"abstract":"Many kidney transplant recipients continue to experience high symptom burden despite restoration of kidney function. High symptom burden is a significant driver of quality of life. In the post-transplant setting, high symptom burden has been linked to negative outcomes including medication non-adherence, allograft rejection, graft loss, and even mortality. Symbiotic bacteria (microbiota) in the human gastrointestinal tract critically interact with the immune, endocrine, and neurological systems to maintain homeostasis of the host. The gut microbiome has been proposed as an underlying mechanism mediating symptoms in several chronic medical conditions including irritable bowel syndrome, chronic fatigue syndrome, fibromyalgia, and psychoneurological disorders via the gut-brain-microbiota axis, a bidirectional signaling pathway between the enteric and central nervous system. Post-transplant exposure to antibiotics, antivirals, and immunosuppressant medications results in significant alterations in gut microbiota community composition and function, which in turn alter these commensal microorganisms' protective effects. This overview will discuss the current state of the science on the effects of the gut microbiome on symptom burden in kidney transplantation and future directions to guide this field of study.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"636-656"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141246707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aerobic Exercise Improves Heart Rate Variability After an Implantable Cardioverter Defibrillator (ICD). 有氧运动可改善植入心律转复除颤器 (ICD) 后的心率变异性。

Biological research for nursing Pub Date : 2024-10-01 Epub Date: 2024-06-16 DOI: 10.1177/10998004241261273

Cynthia M Dougherty, Makayla Cordoza, Di Wang, Afnan Hamad Alsoyan, Phyllis K Stein, Robert L Burr

引用次数: 0

Effects of Astaxanthin Supplementation on Fatigue, Motor Function and Cognition: A Meta-Analysis of Randomized Controlled Trials. 补充虾青素对疲劳、运动功能和认知的影响：随机对照试验的元分析》。

Biological research for nursing Pub Date : 2024-07-01 Epub Date: 2024-01-20 DOI: 10.1177/10998004241227561

Changjiang Liu, Xiaoling Dong, Jia Jia, Mei Ha

{"title":"Effects of Astaxanthin Supplementation on Fatigue, Motor Function and Cognition: A Meta-Analysis of Randomized Controlled Trials.","authors":"Changjiang Liu, Xiaoling Dong, Jia Jia, Mei Ha","doi":"10.1177/10998004241227561","DOIUrl":"10.1177/10998004241227561","url":null,"abstract":"Dietary astaxanthin supplementation has been demonstrated to have many beneficial and health-promoting effects. The purpose of this systematic review and meta-analysis was to assess the effect of astaxanthin supplementation on fatigue, cognition, and exercise efficiency. A total of 11 randomized controlled trials (RCTs) with 346 healthy participants were included. The random effects model and pooled standardized mean difference (SMDs) were used according to Hedge's g for the meta-analysis, and a meta-regression was also conducted. The results of the two existing studies showed a positive trend for astaxanthin in subjective fatigue relief. The effects of astaxanthin supplementation for 8-12 weeks on cognitive accuracy were marginally significant (SMD: .12; 95% CI: -.02-.26) and on reaction time was not significant (SMD: -.08; 95% CI: -.26 to .10). Remarkably, astaxanthin supplementation combined with regular training could enhance the fat oxidation (SMD: 2.56; 95% CI: 1.24-3.89), and significantly improve the physical performance (SMD: .62; 95% CI: .17-1.06). The subgroup analysis further showed significantly greater benefits when performing the aerobic exercises performance (SMD: .45; 95% CI: .13-.76), when the dose was ≥ 20 mg (SMD: .37; 95% CI: .11-.63), and when the supplementation duration was > 12 weeks (SMD: .66; 95% CI: .13-.63). We conclude that astaxanthin supplementation could significantly enhance aerobic exercise efficiency, especially at higher doses and for longer durations. Further studies based on large sample sizes are imperatively warranted.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"469-480"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influencing Factors of Constipation in Elderly Patients With Intracerebral Hemorrhage: Implication for Clinical Care. 老年脑出血患者便秘的影响因素：对临床护理的启示

Biological research for nursing Pub Date : 2024-07-01 Epub Date: 2024-02-26 DOI: 10.1177/10998004241229181

Meng Wang, Jue Lu, Ziwei Lu, Zhong Wang, Zhuo Wang, Chao Wu

{"title":"Influencing Factors of Constipation in Elderly Patients With Intracerebral Hemorrhage: Implication for Clinical Care.","authors":"Meng Wang, Jue Lu, Ziwei Lu, Zhong Wang, Zhuo Wang, Chao Wu","doi":"10.1177/10998004241229181","DOIUrl":"10.1177/10998004241229181","url":null,"abstract":"Background: Constipation is common in elderly inpatients with intracerebral hemorrhage. This study aimed to construct a model for predicting the risk of constipation in elderly inpatients with intracerebral hemorrhage and to provide reference for formulating targeted intervention measures. Methods: Elderly patients with intracerebral hemorrhage who were treated in the department of Neurosurgery of a third-class hospital in Suzhou from January 2018 to September 2023 were included. Clinical data of patients with and without constipation were compared. Logistic regression analysis was used to explore the influencing factors of constipation in elderly patients with intracerebral hemorrhage, and R software was used to construct a line chart model to verify its predictive effect. Results: A total of 504 elderly patients with intracerebral hemorrhage were included. The incidence of constipation in elderly patients with cerebral hemorrhage was 63.9%. Logistic regression analysis showed that GCS score (OR = 1.094, 95%CI: 1.019∼1.174), hypertension (OR = 2.911, 95%CI: 1.797∼4.715), use of dehydrating agent (OR = 3.794, 95%CI: 2.337∼6.158), surgical treatment (OR = 3.986, 95%CI: 2.339∼6.793), use of sedative drugs (OR = 4.212, 95%CI:2.386-7.435), and limb paralysis (OR = 6.313, 95%CI:3.689∼10.803) were the independent risk factors for constipation in elderly patients with intracerebral hemorrhage. The area under the ROC curve of the prediction model was 0.872 (95%CI: 0.8401∼0.9033), the best critical value was 0.705, the sensitivity was 0.748, and the specificity was 0.857. Conclusion: The constipation risk prediction model of elderly patients with cerebral hemorrhage has good differentiation and calibration, which is helpful for health care providers to identify the risk of constipation in elderly patients with intracerebral hemorrhage.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"390-398"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139974980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salivary Diurnal Cortisol Predicts Post-Traumatic Stress Symptoms in Parents of Infants With Congenital Heart Disease. 唾液腺日皮质醇可预测先天性心脏病婴儿父母的创伤后应激症状

Biological research for nursing Pub Date : 2024-07-01 Epub Date: 2024-01-02 DOI: 10.1177/10998004231224791

Amy Jo Lisanti, Fanghong Dong, Abigail Demianczyk, Maria G Vogiatzi, Ryan Quinn, Jesse Chittams, Rebecca Hoffman, Barbara Medoff Cooper

{"title":"Salivary Diurnal Cortisol Predicts Post-Traumatic Stress Symptoms in Parents of Infants With Congenital Heart Disease.","authors":"Amy Jo Lisanti, Fanghong Dong, Abigail Demianczyk, Maria G Vogiatzi, Ryan Quinn, Jesse Chittams, Rebecca Hoffman, Barbara Medoff Cooper","doi":"10.1177/10998004231224791","DOIUrl":"10.1177/10998004231224791","url":null,"abstract":"Background: Parents of infants born with congenital heart disease (CHD) who require open heart surgery after birth are at risk for prolonged psychological distress. Even after their infants are discharged, parents may experience anxiety, depressive, and post-traumatic stress (PTS) symptoms; yet, it is unclear which parents are at greater risk for ongoing symptoms. The purpose of this study was to explore whether measures of the biomarker cortisol in parents during their infants' postoperative period were associated with subsequent psychological distress symptoms at three-month post discharge.Methods: This was a prospective, longitudinal exploratory study of 40 parents of infants with CHD after open heart surgery using consecutive enrollment. Parents provided diurnal saliva samples for two consecutive days in the postoperative period. Six predictors were summarized and generated including waking cortisol, bedtime cortisol, cortisol awaking response, area under curve with respect to the ground (AUCg), cortisol index, and cortisol slope. Self-report outcome measures on anxiety, depressive, and PTS symptoms were collected three-months post-discharge. Linear mixed models examined the associations between each predictor and each outcome while accounting for within-dyad variance using an unstructured covariance matrix.Results: Cortisol AUCg was a predictor of PTS at three-months post-discharge (β = .34, p = .03, Cohen's d = 2.05). No significant relationships were found with the other cortisol measures.Conclusions & implications: Findings suggest that cortisol area under curve may help to identify parents at risk for increased PTS in the months following their infants' hospitalization for cardiac surgery, serving as a foundation for future study in this area.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"341-349"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11131345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139081173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship Between Sleep Duration and Cognitive Function in Older Adults: Analysis of NHANES and UK Biobank GWAS Data. 老年人睡眠时间与认知功能之间的关系：NHANES和英国生物库GWAS数据分析。

Biological research for nursing Pub Date : 2024-07-01 Epub Date: 2024-02-01 DOI: 10.1177/10998004241230325

Min Yu, Yang Jiang, Xu Gong, Xuemei Gao

{"title":"Relationship Between Sleep Duration and Cognitive Function in Older Adults: Analysis of NHANES and UK Biobank GWAS Data.","authors":"Min Yu, Yang Jiang, Xu Gong, Xuemei Gao","doi":"10.1177/10998004241230325","DOIUrl":"10.1177/10998004241230325","url":null,"abstract":"Objectives: To explore the relationship between sleep duration and cognitive functions in older adults using NHANES, a national US population study dataset, and to explore the causal association with Mendelian randomization (MR) using the UK Biobank.Methods: First, an observational study was conducted with the NHANES database with participants ≥60 years. Sleep duration was measured with accelerometers for 7 consecutive days. Participants were divided into habitual short sleep (<7 h) and long sleep (>9 h) groups. Cognitive functions were measured with the CERAD Word Learning sub-set, Animal Fluency, and Digit Symbol Substitution test (DSST). Multivariate regression models were used to explore relationships between sleep duration and cognitive functions. Second, bidirectional MR was conducted with data for self-reported sleep duration, which came from a genome-wide association study (GWAS) comprising 446,118 adults from the UK Biobank, and general cognitive performance, which was obtained from a recent GWAS study (N = 257,841). Inverse-variance weighted (IVW) was used as the primary estimation of the outcome.Results: In the observational study, 2687 participants were included. Sleep duration was associated with cognitive functions in a non-linear way. Habitual long sleep (>9°h) was associated with lower scores on DSST (OR = 0.01, p = .003) in the fully-adjusted model. The association between habitual short sleep and cognitive functions was insignificant. For the MR, genetically predicted lower general cognitive performance was causally associated with a higher prevalence of habitual short sleep (OR = 0.97, p = 5.1 × 10-7) and long sleep (OR = 0.97, p = 8.87 × 10-16).Discussion: Short and long sleep duration might be both causally associated with worse outcomes of cognitive functions in older adults, highlighting the importance of maintaining sleep health.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"399-409"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors Associated With the Cardiovascular Health of Black and Latino Adults With Type 2 Diabetes. 与患有 2 型糖尿病的黑人和拉丁裔成年人心血管健康有关的因素。

Biological research for nursing Pub Date : 2024-07-01 Epub Date: 2024-03-06 DOI: 10.1177/10998004241238237

Margaret M McCarthy, Jason Fletcher, Fay Wright, Inés Del Giudice, Agnes Wong, Bradley E Aouizerat, Victoria Vaughan Dickson, Gail D'Eramo Melkus

{"title":"Factors Associated With the Cardiovascular Health of Black and Latino Adults With Type 2 Diabetes.","authors":"Margaret M McCarthy, Jason Fletcher, Fay Wright, Inés Del Giudice, Agnes Wong, Bradley E Aouizerat, Victoria Vaughan Dickson, Gail D'Eramo Melkus","doi":"10.1177/10998004241238237","DOIUrl":"10.1177/10998004241238237","url":null,"abstract":"Aims: The purpose of this study was to assess the levels of cardiovascular health (CVH) of Black and Latino adults with type 2 diabetes (T2D) and examine the association of individual and microsystem level factors with their CVH score.Methods: This was a cross-sectional design in 60 Black and Latino Adults aged 18-40 with T2D. Data were collected on sociodemographic, individual (sociodemographic, diabetes self-management, sleep disturbance, depressive symptoms, quality of life, and the inflammatory biomarkers IL-6 and hs-CRP) and microsystem factors (family functioning), and American Heart Association's Life's Simple 7 metrics of CVH. Factors significantly associated with the CVH score in the bivariate analyses were entered into a linear regression model.Results: The sample had a mean age 34 ± 5 years and was primarily female (75%) with a mean CVH score was 8.6 ± 2.2 (possible range of 0-14). The sample achieved these CVH factors at ideal levels: body mass index <25 kg/m2 (8%); blood pressure <120/80 (42%); hemoglobin A1c < 7% (57%); total cholesterol <200 mg/dL (83%); healthy diet (18%); never or former smoker > one year (95%); and physical activity (150 moderate-to-vigorous minutes/week; 45%). In the multivariable model, two factors were significantly associated with cardiovascular health: hs-CRP (B = -0.11621, p < .0001) and the general health scale (B = 0.45127, p = .0013).Conclusions: This sample had an intermediate level of CVH, with inflammation and general health associated with overall CVH score.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"438-448"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140051283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk Factors Analysis and Pathogen Distribution of Urinary Tract Infection in Patients Undergoing Cutaneous Ureterostomy After Radical Cystectomy for Bladder Cancer. 膀胱癌根治性切除术后接受皮下输尿管造口术患者尿路感染的风险因素分析和病原体分布

Biological research for nursing Pub Date : 2024-07-01 Epub Date: 2024-01-09 DOI: 10.1177/10998004241226948

Mu-Rong Zhu, Han-Xia Hong, Jing-Ru Cheng, Jing Tang, Tong Lu, Rui Xie

{"title":"Risk Factors Analysis and Pathogen Distribution of Urinary Tract Infection in Patients Undergoing Cutaneous Ureterostomy After Radical Cystectomy for Bladder Cancer.","authors":"Mu-Rong Zhu, Han-Xia Hong, Jing-Ru Cheng, Jing Tang, Tong Lu, Rui Xie","doi":"10.1177/10998004241226948","DOIUrl":"10.1177/10998004241226948","url":null,"abstract":"Background: Postoperative urinary tract infection is a common complication that not only significantly prolongs the hospital stay and amplifies the economic burden on patients, but also affects their quality of life and prognosis. This study aimed to investigate risk factors and distribution of pathogenic bacteria in urinary tract infections among bladder cancer patients who underwent cutaneous ureterostomy following radical cystectomy.Methods: A total of 137 bladder cancer patients, who underwent cutaneous ureterostomy after radical cystectomy at our hospital from November 2018 to October 2022, were enrolled in this retrospective study. Univariate and multivariate logistic regression analyses were employed to investigate the risk factors associated with postoperative urinary tract infection and the distribution of pathogenic bacteria among the infected patients.Results: The results of both univariate and multivariate analyses confirmed that age, proficiency in ostomy knowledge, frequency of ureteral stent tube replacement, ureteral stent tube dislodgement, urine immersion at the outer end of the ureteral stent tube, and the interval of ostomy bag replacement were independent risk factors for urinary tract infection after radical cystectomy and cutaneous ureterostomy in bladder cancer patients. A total of 55 pathogenic bacteria were isolated from 52 patients with infections. Predominantly, these were gram-negative bacteria (34 strains, 61.8%), with Proteus mirabilis having the highest proportion.Conclusion: Urinary tract infections after radical cystectomy and cutaneous ureterostomy predominantly involve gram-negative bacteria. This is correlated with factors such as the age of bladder cancer patients, the level of nursing education, the duration of ureteral stent tubes and ostomy bag usage, as well as issues related to impaired urine drainage.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"361-367"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139405647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0