开发并验证社区老年人吞咽困难预测模型

Yufeng Qiu, Wenfeng Xue, Yanxin Chen, Xiaona He, Lancai Zhao, Mengling Tang, Huafang Zhang
{"title":"开发并验证社区老年人吞咽困难预测模型","authors":"Yufeng Qiu, Wenfeng Xue, Yanxin Chen, Xiaona He, Lancai Zhao, Mengling Tang, Huafang Zhang","doi":"10.1177/10998004241290727","DOIUrl":null,"url":null,"abstract":"<p><p><b>Objectives.</b> Dysphagia is a geriatric syndrome, which may lead to complications such as dehydration, malnutrition, aspiration, pneumonia, and a significant reduction in quality of life. The purpose of this study was to construct and validate a prediction model for dysphagia in community-dwelling older adults and provide an assessment tool for the prevention and control of dysphagia. <b>Design.</b> Cross-sectional study. <b>Setting.</b> The community-dwelling Chinese older adults. <b>Participants.</b> 3655 participants aged 65 years and older were involved, who were randomly divided into the training set and the validation set. <b>Methods.</b> Data were collected and analyzed from June 2022 to September 2022. Univariate and multivariate logistic regression analysis were used to identify independent risk factors for dysphagia. We applied R software to develop a nomogram model to predict dysphagia in community-dwelling older adults. The predictive value of the model was assessed by the area under the ROC curve (AUC), the calibration curve was used to evaluate the reliability of the nomogram model for predicting dysphagia in community-dwelling older adults. The model's clinical utility was further evaluated using a Decision Curve Analysis (DCA). <b>Results.</b> The incidence of dysphagia was 11.8% (320/3655). Maximum tongue pressure, number of molars, pneumonia, ADL, sarcopenia, age, neurological diseases, and rheumatic immune diseases were selected as risk predictors for dysphagia. The prediction model demonstrated fair discriminative ability with the AUC was 0.709 (95%CI: 0.679-0.739) in the training set and 0.693 (95%Cl: 0.640-0.747) in the validation set, the calibration is adequate, and the Hosmer and Lemeshow test showed <i>p</i> values of 0.163 and 0.415, respectively. The DCA curve of our model shows a positive clinical net benefit. <b>Conclusions.</b> The prediction model established in this study was of a certain predictive value for the risk of dysphagia in community-dwelling older adults. By estimating the likelihood of future outcomes or the onset of certain diseases, it can assist medical personnel in formulating preventive strategies, lessening the workload of nurses, and also diminishing the financial burden on patients, thereby enhancing their overall quality of life.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004241290727"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Development and Validation of a Prediction Model for Dysphagia in Community-Dwelling Older Adults.\",\"authors\":\"Yufeng Qiu, Wenfeng Xue, Yanxin Chen, Xiaona He, Lancai Zhao, Mengling Tang, Huafang Zhang\",\"doi\":\"10.1177/10998004241290727\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Objectives.</b> Dysphagia is a geriatric syndrome, which may lead to complications such as dehydration, malnutrition, aspiration, pneumonia, and a significant reduction in quality of life. The purpose of this study was to construct and validate a prediction model for dysphagia in community-dwelling older adults and provide an assessment tool for the prevention and control of dysphagia. <b>Design.</b> Cross-sectional study. <b>Setting.</b> The community-dwelling Chinese older adults. <b>Participants.</b> 3655 participants aged 65 years and older were involved, who were randomly divided into the training set and the validation set. <b>Methods.</b> Data were collected and analyzed from June 2022 to September 2022. Univariate and multivariate logistic regression analysis were used to identify independent risk factors for dysphagia. We applied R software to develop a nomogram model to predict dysphagia in community-dwelling older adults. The predictive value of the model was assessed by the area under the ROC curve (AUC), the calibration curve was used to evaluate the reliability of the nomogram model for predicting dysphagia in community-dwelling older adults. The model's clinical utility was further evaluated using a Decision Curve Analysis (DCA). <b>Results.</b> The incidence of dysphagia was 11.8% (320/3655). Maximum tongue pressure, number of molars, pneumonia, ADL, sarcopenia, age, neurological diseases, and rheumatic immune diseases were selected as risk predictors for dysphagia. The prediction model demonstrated fair discriminative ability with the AUC was 0.709 (95%CI: 0.679-0.739) in the training set and 0.693 (95%Cl: 0.640-0.747) in the validation set, the calibration is adequate, and the Hosmer and Lemeshow test showed <i>p</i> values of 0.163 and 0.415, respectively. The DCA curve of our model shows a positive clinical net benefit. <b>Conclusions.</b> The prediction model established in this study was of a certain predictive value for the risk of dysphagia in community-dwelling older adults. By estimating the likelihood of future outcomes or the onset of certain diseases, it can assist medical personnel in formulating preventive strategies, lessening the workload of nurses, and also diminishing the financial burden on patients, thereby enhancing their overall quality of life.</p>\",\"PeriodicalId\":93901,\"journal\":{\"name\":\"Biological research for nursing\",\"volume\":\" \",\"pages\":\"10998004241290727\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-10-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biological research for nursing\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/10998004241290727\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biological research for nursing","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/10998004241290727","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

目的。吞咽困难是一种老年综合症,可能导致脱水、营养不良、吸入、肺炎等并发症,并显著降低生活质量。本研究旨在构建并验证社区老年人吞咽困难预测模型,为预防和控制吞咽困难提供评估工具。设计。横断面研究。环境。社区居住的中国老年人。参与者3655 名 65 岁及以上的参与者,随机分为训练集和验证集。方法。收集和分析 2022 年 6 月至 2022 年 9 月期间的数据。采用单变量和多变量逻辑回归分析来确定吞咽困难的独立风险因素。我们应用 R 软件开发了一个预测社区老年人吞咽困难的提名图模型。该模型的预测价值通过 ROC 曲线下面积(AUC)进行评估,校准曲线用于评估该提名图模型预测社区老年人吞咽困难的可靠性。使用决策曲线分析法(DCA)进一步评估了该模型的临床实用性。结果显示吞咽困难发生率为 11.8%(320/3655)。最大舌压、臼齿数、肺炎、ADL、肌肉疏松症、年龄、神经系统疾病和风湿免疫疾病被选为吞咽困难的风险预测因素。预测模型显示出相当的判别能力,训练集的AUC为0.709(95%CI:0.679-0.739),验证集的AUC为0.693(95%Cl:0.640-0.747),校准充分,Hosmer和Lemeshow检验的P值分别为0.163和0.415。我们模型的 DCA 曲线显示临床净获益为正。结论。本研究建立的预测模型对社区老年人吞咽困难的风险具有一定的预测价值。通过对未来结果或某些疾病发病的可能性进行估计,可以帮助医务人员制定预防策略,减轻护士的工作量,同时减轻患者的经济负担,从而提高他们的整体生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Development and Validation of a Prediction Model for Dysphagia in Community-Dwelling Older Adults.

Objectives. Dysphagia is a geriatric syndrome, which may lead to complications such as dehydration, malnutrition, aspiration, pneumonia, and a significant reduction in quality of life. The purpose of this study was to construct and validate a prediction model for dysphagia in community-dwelling older adults and provide an assessment tool for the prevention and control of dysphagia. Design. Cross-sectional study. Setting. The community-dwelling Chinese older adults. Participants. 3655 participants aged 65 years and older were involved, who were randomly divided into the training set and the validation set. Methods. Data were collected and analyzed from June 2022 to September 2022. Univariate and multivariate logistic regression analysis were used to identify independent risk factors for dysphagia. We applied R software to develop a nomogram model to predict dysphagia in community-dwelling older adults. The predictive value of the model was assessed by the area under the ROC curve (AUC), the calibration curve was used to evaluate the reliability of the nomogram model for predicting dysphagia in community-dwelling older adults. The model's clinical utility was further evaluated using a Decision Curve Analysis (DCA). Results. The incidence of dysphagia was 11.8% (320/3655). Maximum tongue pressure, number of molars, pneumonia, ADL, sarcopenia, age, neurological diseases, and rheumatic immune diseases were selected as risk predictors for dysphagia. The prediction model demonstrated fair discriminative ability with the AUC was 0.709 (95%CI: 0.679-0.739) in the training set and 0.693 (95%Cl: 0.640-0.747) in the validation set, the calibration is adequate, and the Hosmer and Lemeshow test showed p values of 0.163 and 0.415, respectively. The DCA curve of our model shows a positive clinical net benefit. Conclusions. The prediction model established in this study was of a certain predictive value for the risk of dysphagia in community-dwelling older adults. By estimating the likelihood of future outcomes or the onset of certain diseases, it can assist medical personnel in formulating preventive strategies, lessening the workload of nurses, and also diminishing the financial burden on patients, thereby enhancing their overall quality of life.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信