Archivos de la Sociedad Espanola de Oftalmologia最新文献_第9页

Endothelial changes in patients with and without diabetes after manual small-incision cataract surgery 糖尿病患者和非糖尿病患者手工小切口白内障术后内皮细胞的变化。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.016

L.A. Oseguera Chávez, L.E. Salas Medina, C. Palacio Pastrana, W. Cedillo Suárez

{"title":"Endothelial changes in patients with and without diabetes after manual small-incision cataract surgery","authors":"L.A. Oseguera Chávez, L.E. Salas Medina, C. Palacio Pastrana, W. Cedillo Suárez","doi":"10.1016/j.oftale.2025.03.016","DOIUrl":"10.1016/j.oftale.2025.03.016","url":null,"abstract":"<div><h3>Background and objective</h3><div>In Mexico there is a high prevalence of diabetes, which is one of the most frequent etiologies of cataract. The impact of diabetes on postoperative corneal decompensation associated with MSICS has not been studied in our country. The objective of the study was to determine the difference in corneal endothelial changes between diabetic and non-diabetic patients by preoperative specular microscopy and at one month and 3 months after MSICS.</div></div><div><h3>Patients and methods</h3><div>Prospective, longitudinal, paired, non-randomized study with two groups; Group 1: diabetic patients and Group 2: non-diabetic patients. All patients had a complete ophthalmologic evaluation and preoperative and postoperative specular microscopy at one month and 3 months.</div></div><div><h3>Results</h3><div>119 eyes were included. The percentage of CD loss at 1 month was 11.1% in diabetic patients and 6.3% in non-diabetic patients. At 3 months the percentage of loss was 9.9% in diabetic patients and 5.4% in non-diabetic patients. The CV was higher in patients with diabetes and was significant at 1 month; however, at 3 months the values were comparable. The percentage of HEX decreased significantly in the first month in patients with diabetes.</div></div><div><h3>Conclusions</h3><div>There was a significant difference with greater CD loss, greater CV and less HEX in patients with diabetes vs. without diabetes at 1 month after the M-SICS procedure, however, it was not statistically significant at 3 months. This suggests greater endothelial stress, longer recovery time and remodeling of the corneal endothelium in patients with diabetes.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 246-253"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling the Enigma: Gigantic primary de novo poorly-differentiated ductal adenocarcinoma of the lacrimal gland with aggressive features. A case report and literature review 揭开谜团：巨大的原发性泪腺低分化导管腺癌，具有侵袭性特征。病例报告及文献复习。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.018

S. Malik, C. Ahluwalia, A. Aziz Khan

{"title":"Unveiling the Enigma: Gigantic primary de novo poorly-differentiated ductal adenocarcinoma of the lacrimal gland with aggressive features. A case report and literature review","authors":"S. Malik, C. Ahluwalia, A. Aziz Khan","doi":"10.1016/j.oftale.2025.03.018","DOIUrl":"10.1016/j.oftale.2025.03.018","url":null,"abstract":"<div><div>Primary ductal adenocarcinoma (PDA) of the lacrimal gland is a rare and aggressive malignancy originating from ductal epithelial cells. Its rarity and diverse clinical presentations pose significant diagnostic challenges, emphasizing the need for accurate diagnosis and appropriate management strategies. The study presents an intriguing case of a 50-year-old man with a large de novo primary ductal adenocarcinoma of the lacrimal gland, initially misdiagnosed as a meningeal solitary fibrous tumor due to its atypical clinical presentation of “down and out” proptosis. The case underscores the importance of histopathology to achieve a correct diagnosis and guide management decisions. Despite aggressive treatment approaches, the prognosis of primary ductal adenocarcinoma patients remains grim due to its aggressive behavior and tendency for recurrence and metastasis. The present case study emphasizes that a differential of primary ductal adenocarcinoma should be considered despite the presence of anomalous clinical and radiological presentation.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 295-301"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serious incidents involving ocular medical devices reported to the AEMPS 向AEMPS报告的涉及眼科医疗器械的严重事故。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.008

L.C. Ramón-Carreira , E.M. Sobas , J.C. Pastor

引用次数: 0

Williams-Beuren syndrome case series with thinner fovea centralis and central corneal thicknesses Williams-Beuren综合征的病例系列与较薄的中央凹和角膜中央厚度。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.01.012

G. Yılmaz , G. Demirci , S. Karaman , M. Sargolzaeimoghaddam , E.S. Uluçam , A. Sarg

{"title":"Williams-Beuren syndrome case series with thinner fovea centralis and central corneal thicknesses","authors":"G. Yılmaz , G. Demirci , S. Karaman , M. Sargolzaeimoghaddam , E.S. Uluçam , A. Sarg","doi":"10.1016/j.oftale.2025.01.012","DOIUrl":"10.1016/j.oftale.2025.01.012","url":null,"abstract":"<div><h3>Background/aims</h3><div>To characterize the ocular signs of Williams-Beuren syndrome (WBS) in 3 cases examined at XXX University Ophthalmology Clinic.</div></div><div><h3>Methods</h3><div>Three patients with a diagnosis of WBS underwent comprehensive ophthalmic evaluation at the XXX University Ophthalmology, including best-corrected visual acuity, slitlamp biomicroscopy, dilated fundus examination, optical coherence tomography, corneal topography and colour fundus imaging.</div></div><div><h3>Results</h3><div>All 3 cases had decreased best corrected visual acuity, decreased ILM-RNFL thicknesses with a persistence of inner retinal layers on the SD-OCT examinations, decreased central corneal thickness yet normal epithelial thickness measurements and retinal arteriolar tortuosity in fundus examination.</div></div><div><h3>Conclusion</h3><div>WBS is a complex multisystem genetic disorder. The ocular findings observed in these cases which are decreased corneal thickness with normal epithelial thickness, decreased ILM-RPE thicknesses, and retinal arteriolar tortuosity may provide future insight into systemic vascular findings affected by a microdeletion of chromosome 7q11.23 which also contains elastin gene in WBS.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 238-245"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cytokine analysis to evaluate severity in primary open-angle glaucoma and exfoliative glaucoma 细胞因子分析评价原发性开角型青光眼和剥脱性青光眼的严重程度。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.019

L. Gallardo Martin , B. Burgos-Blasco , B. Vidal-Villegas , J.I. Fernandez-Vigo , J. Garcia-Feijoo , J.M. Martinez-de-la-Casa

{"title":"Cytokine analysis to evaluate severity in primary open-angle glaucoma and exfoliative glaucoma","authors":"L. Gallardo Martin , B. Burgos-Blasco , B. Vidal-Villegas , J.I. Fernandez-Vigo , J. Garcia-Feijoo , J.M. Martinez-de-la-Casa","doi":"10.1016/j.oftale.2025.03.019","DOIUrl":"10.1016/j.oftale.2025.03.019","url":null,"abstract":"<div><h3>Purpose</h3><div>To analyze cytokines in tear and aqueous humour as biomarkers for evaluation of severity of glaucoma.</div></div><div><h3>Design</h3><div>Cross-sectional study.</div></div><div><h3>Subjects and methods</h3><div>Tear and aqueous humour samples were collected from 15 exfoliative glaucoma (XFG) patients, 43 primary open-angle glaucoma (POAG) patients and 33 controls (eligible for cataract surgery).</div><div>A total of 27 inflammatory cytokines were analyzed in the tear and aqueous humor samples by the Bio-Plex Pro Human Cytokine 27-Plex Immunoassay kit: interleukin (IL)-1b, IL-1ra, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL9, IL-10, IL-12, IL-13, IL-15, IL-17, eotaxin, fibroblast growth factor (FGF) basic, granulocyte colony-stimulating factor, granulocyte-monocyte colony-stimulating factor, interferon-γ, interferon gamma-induced protein, monocyte chemo-attractant protein-1, macrophage inflammatory protein (MIP)-1a, MIP-1b, platelet-derived growth factor, regulated on activation normal T cell expressed and secreted, tumor necrosis factor-α and vascular endothelial growth factor.</div></div><div><h3>Results</h3><div>In the tear samples a statistically significant difference in Il-2, IL-4, IL-9, IL-12, IL-15 and FGF-basic between study groups was observed. In aqueous humor, a statistically significant difference of the following cytokines was observed: IL-5, IL-6, IL-12 and MCP-1. Il-4 and IL-15 differences correlate with the number of topical drugs, while IL-9 and IL-15 are associated with the visual field mean defect.</div></div><div><h3>Conclusion</h3><div>Inflammation is strongly associated with glaucoma and some cytokines may be related to glaucoma severity.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 254-263"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of primary rhegmatogenous retinal detachment. Necessity and importance of scleral buckling surgery 原发性孔源性视网膜脱离的治疗。巩膜屈曲手术的必要性和重要性。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.04.002

L. López Guajardo , F. Armadá Maresca , F. González del Valle

引用次数: 0

Retinopathy associated with facioscapulohumeral muscular dystrophy. A case report treated with intravitreal dexamethasone implant and laser photocoagulation 视网膜病变伴面肩肱肌营养不良。玻璃体内植入地塞米松联合激光光凝治疗1例。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.014

A.B. González Escobar, I.E. Molina Guilabert, R.M. García Herrera, I.M. Baquero Aranda, R. Luque Aranda, J.M. Galván Cano

{"title":"Retinopathy associated with facioscapulohumeral muscular dystrophy. A case report treated with intravitreal dexamethasone implant and laser photocoagulation","authors":"A.B. González Escobar, I.E. Molina Guilabert, R.M. García Herrera, I.M. Baquero Aranda, R. Luque Aranda, J.M. Galván Cano","doi":"10.1016/j.oftale.2025.03.014","DOIUrl":"10.1016/j.oftale.2025.03.014","url":null,"abstract":"<div><div>Facioscapulohumeral muscular dystrophy (FSHD) is a slowly progressive muscular dystrophy that affects especially the muscles of the face, shoulder girdle and upper arms. It may present extramuscular manifestations such as hearing loss and retinopathy. Up to 75% of patients may show alterations in the retinal vasculature such as vascular tortuosity, microaneurysms, telangiectasias, retinal ischemia and exudation, and in less than 1% of cases it may present as Coats-like syndrome. We present a 40-year-old male with FSHD who, in an ophthalmologic examination, showed exudative retinopathy in his left eye (LE) with peripheral retinal ischemia treated with laser therapy, and macular edema (ME) treated with intravitreal dexamethasone injection (IDI).</div><div>We would like to emphasize the importance of performing an ophthalmological examination on all patients with FSHD to rule out associated retinal pathology, and thus prevent loss of visual acuity (VA) with early treatment.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 283-288"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Central toxic keratopathy after refractive surgery: Diagnosis, treatment and challenges in the routine clinical practice 屈光手术后中枢性中毒性角膜病变：诊断、治疗及常规临床实践中的挑战。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.015

A. Robles García , Y. Fernández Barrientos , J.L. Ramos Navarro , J. Díaz Bernal , J. Mora Castilla , J. Ortega Usobiaga

引用次数: 0

Study of a single eye bank. Characteristics and progression of corneal transplantation from 2016 through 2022 in Galicia (Spain) 单一眼库的研究。加利西亚（西班牙）2016 - 2022年角膜移植的特点和进展

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.04.005

L. Zurutuza-Veillet , M.A. Saavedra-García , M. Álvarez-Portela , J. Suanzes-Hernández

{"title":"Study of a single eye bank. Characteristics and progression of corneal transplantation from 2016 through 2022 in Galicia (Spain)","authors":"L. Zurutuza-Veillet , M.A. Saavedra-García , M. Álvarez-Portela , J. Suanzes-Hernández","doi":"10.1016/j.oftale.2025.04.005","DOIUrl":"10.1016/j.oftale.2025.04.005","url":null,"abstract":"<div><h3>Objective</h3><div>To describe the characteristics of donated and transplanted corneas, trends in surgical techniques, and indications for corneal transplantation, and the impact of COVID-19 on a Spanish tissue bank from 2016 through 2022.</div></div><div><h3>Methods</h3><div>We conducted a retrospective analysis of corneal donation records from C<em>omplejo Hospitalario Universitario de A Coruña</em> Cryobiology Unit and Tissue Bank from January 1st, 2016 through June 30th, 2022.</div></div><div><h3>Results</h3><div>Corneal donations and transplants remained stable over 6.5 years, except for declines in 2020–2021. A total of 44.3% of all donated corneas were not transplanted, mainly due to tissue viability issues (41.4%). Donors averaged 60.2 ± 13 years, with a mean corneal endothelial cell count of 2701.3 ± 324.6 cells/mm² and a mean corneal clear zone diameter of 7.7 ± 0.7 mm. The preferred preservation method for keratoplasty was hypothermia (85,9%). Indications included endothelial dysfunction (53.8%), repeated keratoplasty (18.8%), corneal ectasia (15.4%), stromal opacity (7.6%), and tectonic causes (4.9%). Penetrating keratoplasty (PK) was more common (56.3%) than lamellar techniques (43.7%), but endothelial keratoplasty (EK) increased by 27.8% since 2019. EK, predominantly Descemet Membrane Endothelial Keratoplasty (DMEK, 94.1%), was used in 96.7% of endothelial dysfunction cases, although 28.6% were treated with PK. Deep anterior lamellar keratoplasty was primarily used for corneal ectasia (46.8%).</div></div><div><h3>Conclusions</h3><div>The Galicia Tissue Bank exceeds the European Eye Bank Association quality standards. Penetrating techniques remain predominant, but the trend is towards favor lamellar procedures, particularly DMEK. Endothelial dysfunction is the leading and growing indication for corneal transplantation.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 264-273"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulsed light therapy in refractory dry eye disease associated with Meibomian gland dysfunction: Effectiveness in symptomatic response 脉冲光治疗与睑板腺功能障碍相关的难治性干眼病：对症状反应的有效性

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-04-01 DOI: 10.1016/j.oftale.2025.01.002

S. Turizo Mejía , L.M. Jaramillo , J.C. Gil Muñoz , J.C. Buitrago Salazar , A.M. Rodríguez Gómez , L.F. Mejía Echavarría , M. Escobar Giraldo

{"title":"Pulsed light therapy in refractory dry eye disease associated with Meibomian gland dysfunction: Effectiveness in symptomatic response","authors":"S. Turizo Mejía , L.M. Jaramillo , J.C. Gil Muñoz , J.C. Buitrago Salazar , A.M. Rodríguez Gómez , L.F. Mejía Echavarría , M. Escobar Giraldo","doi":"10.1016/j.oftale.2025.01.002","DOIUrl":"10.1016/j.oftale.2025.01.002","url":null,"abstract":"<div><h3>Purpose</h3><div>To determine the effectiveness of intense pulsed light (IPL) therapy in improving symptoms in patients with a diagnosis of evaporative dry eye disease secondary to Meibomian gland dysfunction (MGD) refractory to conventional treatment.</div></div><div><h3>Methods</h3><div>Pseudo-experimental, analytical, prospective, longitudinal, interventional study. Patients aged 18-74 years with a diagnosis of dry eye disease refractory to conventional dry eye treatment with the presence of DGM were included. A total of 4 IPL sessions were performed at days 0, 15, 45 and 75. At each visit, ocular surface disease index (OSDI) data and 1-10 analog scale were taken as objective evidence of symptomatic status.</div></div><div><h3>Results</h3><div>Sixty three patients were included, median age was 43 years, 61.5% were female, 42.9% of patients used one conventional treatment for dry eye prior to IPL therapy and 57.1% of patients used two or more treatments. Sixty three patients completed at least one IPL session, 45 had two sessions, 32 had three sessions and 18 had four sessions. After the fourth session symptomatic improvement was 50.8% based on the OSDI scale, and 71.4% based on the analogous symptom scale.</div></div><div><h3>Conclusion</h3><div>This study demonstrates that IPL therapy is effective in symptomatic improvement in patients with MGD diagnosis refractory to conventional treatment, showing that after four sessions in at least 50% of patients both with the OSDI measurement and with the ocular surface symptomatology analog scale.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 4","pages":"Pages 174-179"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0