Psychoradiology最新文献_第3页

Neurostructural changes in schizophrenia and treatment-resistance: a narrative review. 精神分裂症的神经结构变化与耐药性：叙述性综述。

Psychoradiology Pub Date : 2024-09-06 eCollection Date: 2024-01-01 DOI: 10.1093/psyrad/kkae015

Tanya Paul, Jia Whei See, Vetrivel Vijayakumar, Temiloluwa Njideaka-Kevin, Hanyou Loh, Vivian Jia Qi Lee, Bekir Nihat Dogrul

引用次数: 0

Impaired mitochondrial function in bipolar disorder and alcohol use disorder: a case study using ¹⁸F-BCPP-EF PET imaging of mitochondrial Complex I. 双相情感障碍和酒精使用障碍中受损的线粒体功能：使用线粒体复合物 I 的 18F-BCPP-EF PET 成像进行病例研究。

Psychoradiology Pub Date : 2024-09-03 eCollection Date: 2024-01-01 DOI: 10.1093/psyrad/kkae014

Travis P Wigstrom, Stiven Roytman, Jeffrey L B Bohnen, Rebecca R Paalanen, Alexis M Griggs, Robert Vangel, Jaimie Barr, Roger Albin, Prabesh Kanel, Nicolaas I Bohnen

{"title":"Impaired mitochondrial function in bipolar disorder and alcohol use disorder: a case study using 18F-BCPP-EF PET imaging of mitochondrial Complex I.","authors":"Travis P Wigstrom, Stiven Roytman, Jeffrey L B Bohnen, Rebecca R Paalanen, Alexis M Griggs, Robert Vangel, Jaimie Barr, Roger Albin, Prabesh Kanel, Nicolaas I Bohnen","doi":"10.1093/psyrad/kkae014","DOIUrl":"10.1093/psyrad/kkae014","url":null,"abstract":"Background: With bipolar disorder (BD) having a lifetime prevalence of 4.4% and a significant portion of patients being chronically burdened by symptoms, there has been an increased focus on uncovering new targets for intervention in BD. One area that has shown early promise is the mitochondrial hypothesis. However, at the time of publication no studies have utilized positron emission tomography (PET) imaging to assess mitochondrial function in the setting of BD.Case presentation: Our participant is a 58 year-old male with a past medical history notable for alcohol use disorder and BD (unspecified type) who underwent PET imaging with the mitochondrial complex I PET ligand 18F-BCPP-EF. The resulting images demonstrated significant overlap between areas of dysfunction identified with the 18F-BCPP-EF PET ligand and prior functional magnetic resonance imaging (MRI) techniques in the setting of BD. That overlap was seen in both affective and cognitive circuits, with mitochondrial dysfunction in the fronto-limbic, ventral affective, and dorsal cognitive circuits showing particularly significant differences.Conclusions: Despite mounting evidence implicating mitochondria in BD, this study represents the first PET imaging study to investigate this mechanistic connection. There were key limitations in the form of comorbid alcohol use disorder, limited statistical power inherent to a case study, no sex matched controls, and the absence of a comprehensive psychiatric history. However, even with these limitations in mind, the significant overlap between dysfunction previously demonstrated on functional MRI and this imaging provides compelling preliminary evidence that strengthens the mechanistic link between mitochondrial dysfunction and BD.","PeriodicalId":93496,"journal":{"name":"Psychoradiology","volume":"4 ","pages":"kkae014"},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11467810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancements in MR hardware systems and magnetic field control: B₀ shimming, RF coils, and gradient techniques for enhancing magnetic resonance imaging and spectroscopy. 磁共振硬件系统和磁场控制的进步：用于增强磁共振成像和光谱学的 B0 垫片、射频线圈和梯度技术。

Psychoradiology Pub Date : 2024-08-14 eCollection Date: 2024-01-01 DOI: 10.1093/psyrad/kkae013

Yun Shang, Gizeaddis Lamesgin Simegn, Kelly Gillen, Hsin-Jung Yang, Hui Han

{"title":"Advancements in MR hardware systems and magnetic field control: B0 shimming, RF coils, and gradient techniques for enhancing magnetic resonance imaging and spectroscopy.","authors":"Yun Shang, Gizeaddis Lamesgin Simegn, Kelly Gillen, Hsin-Jung Yang, Hui Han","doi":"10.1093/psyrad/kkae013","DOIUrl":"10.1093/psyrad/kkae013","url":null,"abstract":"High magnetic field homogeneity is critical for magnetic resonance imaging (MRI), functional MRI, and magnetic resonance spectroscopy (MRS) applications. B0 inhomogeneity during MR scans is a long-standing problem resulting from magnet imperfections and site conditions, with the main issue being the inhomogeneity across the human body caused by differences in magnetic susceptibilities between tissues, resulting in signal loss, image distortion, and poor spectral resolution. Through a combination of passive and active shim techniques, as well as technological advances employing multi-coil techniques, optimal coil design, motion tracking, and real-time modifications, improved field homogeneity and image quality have been achieved in MRI/MRS. The integration of RF and shim coils brings a high shim efficiency due to the proximity of participants. This technique will potentially be applied to high-density RF coils with a high-density shim array for improved B0 homogeneity. Simultaneous shimming and image encoding can be achieved using multi-coil array, which also enables the development of novel encoding methods using advanced magnetic field control. Field monitoring enables the capture and real-time compensation for dynamic field perturbance beyond the static background inhomogeneity. These advancements have the potential to better use the scanner performance to enhance diagnostic capabilities and broaden applications of MRI/MRS in a variety of clinical and research settings. The purpose of this paper is to provide an overview of the latest advances in B0 magnetic field shimming and magnetic field control techniques as well as MR hardware, and to emphasize their significance and potential impact on improving the data quality of MRI/MRS.","PeriodicalId":93496,"journal":{"name":"Psychoradiology","volume":"4 ","pages":"kkae013"},"PeriodicalIF":0.0,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11384915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142303113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is unilateral cerebellum sufficient? Insights from new cases of cerebellar agenesis and literature review. 单侧小脑是否足够？小脑发育不全新病例的启示和文献综述。

Psychoradiology Pub Date : 2024-06-29 eCollection Date: 2024-01-01 DOI: 10.1093/psyrad/kkae012

Dingmei Deng, Bo Tao, Yizhi Yuan, Yongsheng Ao, Lihua Qiu

{"title":"Is unilateral cerebellum sufficient? Insights from new cases of cerebellar agenesis and literature review.","authors":"Dingmei Deng, Bo Tao, Yizhi Yuan, Yongsheng Ao, Lihua Qiu","doi":"10.1093/psyrad/kkae012","DOIUrl":"10.1093/psyrad/kkae012","url":null,"abstract":"The clinical manifestations of adult-acquired cerebellar diseases often surpass those of congenital cerebellar diseases, suggesting the significant role of the cerebellum in the developing brain. Moreover, emerging evidence from structural and functional magnetic resonance imaging indicates that the cerebellum is implicated not only in motor functions but also in non-motor domains such as cognition, emotion, and language. However, delineating the specific extent of cerebellar development required to prevent deficits in either motor or non-motor functions remains challenging. In this study, we present two new cases of unilateral cerebellar agenesis. One individual leads a nearly normal life, while the other exhibits mild cognitive impairment, mild depression, and severe autism, but maintains normal motor function. Van der Heijden et al. (2023) revealed that the brain can compensate for some, but not all, perturbations to the developing cerebellum, including motor deficits and impairments in social behaviors. Therefore, we hypothesize that comparing structural images from our patients and reviewing pertinent literature may elucidate the reasons for the varied clinical manifestations observed in patients with cerebellar agenesis.","PeriodicalId":93496,"journal":{"name":"Psychoradiology","volume":"4 ","pages":"kkae012"},"PeriodicalIF":0.0,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11253423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141636091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing assessment and intervention for empathy deficits: The “zipper model of empathy” approach in neurodevelopmental disorders 加强移情缺陷的评估和干预：神经发育障碍中的 "移情拉链模型 "方法

Psychoradiology Pub Date : 2024-06-13 DOI: 10.1093/psyrad/kkae011

Yili Zhao

引用次数: 0

Informing the treatment of social anxiety disorder with computational and neuroimaging data 利用计算和神经成像数据为社交焦虑症的治疗提供依据

Psychoradiology Pub Date : 2024-05-03 DOI: 10.1093/psyrad/kkae010

Aamir Sohail, Lei Zhang

引用次数: 0

Social intelligence mediates the protective role of resting-state brain activity in the social cognition network against social anxiety 社交智能介导社会认知网络中静息态大脑活动对社交焦虑的保护作用

Psychoradiology Pub Date : 2024-04-24 DOI: 10.1093/psyrad/kkae009

Yingqiao Ma, Yuhan Zou, Xiqin Liu, Taolin Chen, Graham J. Kemp, Qiyong Gong, Song Wang

{"title":"Social intelligence mediates the protective role of resting-state brain activity in the social cognition network against social anxiety","authors":"Yingqiao Ma, Yuhan Zou, Xiqin Liu, Taolin Chen, Graham J. Kemp, Qiyong Gong, Song Wang","doi":"10.1093/psyrad/kkae009","DOIUrl":"https://doi.org/10.1093/psyrad/kkae009","url":null,"abstract":"\u0000 \u0000 \u0000 Social intelligence refers to an important psychosocial skill set encompassing an array of abilities, including effective self-expression, understanding of social contexts, and acting wisely in social interactions. While there is ample evidence of its importance in various mental health outcomes, particularly social anxiety, little is known on the brain correlates underlying social intelligence and how it can mitigate social anxiety.\u0000 \u0000 \u0000 \u0000 This research aims to investigate the functional neural markers of social intelligence and their relations to social anxiety.\u0000 \u0000 \u0000 \u0000 Data of resting-state functional magnetic resonance imaging and behavioral measures were collected from 231 normal students aged 16 to 20 years (48% male). Whole-brain voxel-wise correlation analysis was conducted to detect the functional brain clusters related to social intelligence. Correlation and mediation analyses explored the potential role of social intelligence in the linkage of resting-state brain activities to social anxiety.\u0000 \u0000 \u0000 \u0000 Social intelligence was correlated with neural activities (assessed as the fractional amplitude of low-frequency fluctuations, fALFF) among two key brain clusters in the social cognition networks: negatively correlated in left superior frontal gyrus (SFG) and positively correlated in right middle temporal gyrus (MTG). Further, the left SFG fALFF was positively correlated with social anxiety; brain–personality-symptom analysis revealed that this relationship was mediated by social intelligence.\u0000 \u0000 \u0000 \u0000 These results indicate that resting-state activities in the social cognition networks might influence a person's social anxiety via social intelligence: lower left SFG activity → higher social intelligence → lower social anxiety. These may have significance for developing neurobehavioral intervention to mitigate social anxiety.\u0000","PeriodicalId":93496,"journal":{"name":"Psychoradiology","volume":"25 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140664820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microbiota-gut-brain axis: the mediator of exercise and brain health. 微生物群-肠-脑轴：运动与大脑健康的媒介。

Psychoradiology Pub Date : 2024-04-19 eCollection Date: 2024-01-01 DOI: 10.1093/psyrad/kkae007

Piao Kang, Alan Zi-Xuan Wang

{"title":"Microbiota-gut-brain axis: the mediator of exercise and brain health.","authors":"Piao Kang, Alan Zi-Xuan Wang","doi":"10.1093/psyrad/kkae007","DOIUrl":"10.1093/psyrad/kkae007","url":null,"abstract":"The brain controls the nerve system, allowing complex emotional and cognitive activities. The microbiota-gut-brain axis is a bidirectional neural, hormonal, and immune signaling pathway that could link the gastrointestinal tract to the brain. Over the past few decades, gut microbiota has been demonstrated to be an essential component of the gastrointestinal tract that plays a crucial role in regulating most functions of various body organs. The effects of the microbiota on the brain occur through the production of neurotransmitters, hormones, and metabolites, regulation of host-produced metabolites, or through the synthesis of metabolites by the microbiota themselves. This affects the host's behavior, mood, attention state, and the brain's food reward system. Meanwhile, there is an intimate association between the gut microbiota and exercise. Exercise can change gut microbiota numerically and qualitatively, which may be partially responsible for the widespread benefits of regular physical activity on human health. Functional magnetic resonance imaging (fMRI) is a non-invasive method to show areas of brain activity enabling the delineation of specific brain regions involved in neurocognitive disorders. Through combining exercise tasks and fMRI techniques, researchers can observe the effects of exercise on higher brain functions. However, exercise's effects on brain health via gut microbiota have been little studied. This article reviews and highlights the connections between these three interactions, which will help us to further understand the positive effects of exercise on brain health and provide new strategies and approaches for the prevention and treatment of brain diseases.","PeriodicalId":93496,"journal":{"name":"Psychoradiology","volume":"4 ","pages":"kkae007"},"PeriodicalIF":0.0,"publicationDate":"2024-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11096970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain development of a school-aged boy with autism spectrum condition talented in arithmetic: a case report. 一名患有自闭症谱系障碍的学龄男孩在算术方面天赋异禀的大脑发育：个案报告。

Psychoradiology Pub Date : 2024-04-18 eCollection Date: 2024-01-01 DOI: 10.1093/psyrad/kkae008

Weixing Zhao, Lei Li, Xiujie Yang, Xiaotian Wang, Juan Kou, Jia Chen, Huafu Chen, Qi Wang, Xujun Duan

{"title":"Brain development of a school-aged boy with autism spectrum condition talented in arithmetic: a case report.","authors":"Weixing Zhao, Lei Li, Xiujie Yang, Xiaotian Wang, Juan Kou, Jia Chen, Huafu Chen, Qi Wang, Xujun Duan","doi":"10.1093/psyrad/kkae008","DOIUrl":"10.1093/psyrad/kkae008","url":null,"abstract":"Whereas autism spectrum condition is known for its social and communicative challenges, some autistic children demonstrate unusual islets of abilities including those related to mathematics, the neurobiological underpinnings of which are increasingly becoming the focus of research. Here we describe an 8-year-old autistic boy with intellectual and language challenges, yet exceptional arithmetic ability. He can perform verbal-based multiplication of three- and even four-digit numbers within 20 seconds. To gain insights into the neural basis of his talent, we investigated the gray matter in the child's brain in comparison to typical development, applying voxel-based morphometry to magnetic resonance imaging data. The case exhibited reduced gray matter volume in regions associated with arithmetic, which may suggest an accelerated development of brain regions with arithmetic compared to typically developing individuals: potentially a key factor contributing to his exceptional talent. Taken together, this case report describes an example of the neurodiversity of autism. Our research provides valuable insights into the potential neural basis of exceptional arithmetic abilities in individuals with the autism spectrum and its potential contribution to depicting the diversity and complexity of autism.","PeriodicalId":93496,"journal":{"name":"Psychoradiology","volume":"4 ","pages":"kkae008"},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11074990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140878143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Focus on the sex-specific neural markers in the discrimination of various degrees of depression 关注鉴别不同程度抑郁症的性别特异性神经标记

Psychoradiology Pub Date : 2024-04-09 DOI: 10.1093/psyrad/kkae006

Yaqin Li, Xinyu Yan, Xianxin Meng, Jiajin Yuan

引用次数: 0