{"title":"Is there racial/ethnic variance in cervical cancer- specific survival of older women in the united states?","authors":"L. Holmes, J. Hossain","doi":"10.4314/IJHR.V2I4.55428","DOIUrl":"https://doi.org/10.4314/IJHR.V2I4.55428","url":null,"abstract":"Purpose: To examine racial/ethnic differences in cervical carcinoma survival of older US women, as well as the impact of income, cell type (tumor histology), tumor stage and treatment on survival of this cohort. Methods: A population-based cohort of women diagnosed with \u0000incident cervical carcinoma, between 1992 and 1999, in the Surveillance Epidemiology and End Results (SEER) Data was linked with Medicare to examine the impact of race/ethnicity on overall and cancer-specific survival, using Kaplan Meier survival estimates and multivariable Cox Regression model. Results: There was no significant racial/ethnic variation in overall and cervical cancer-specific survival. However, the advanced tumor \u0000stage at diagnosis, treatment received and advanced age at tumor diagnosis were the only significant predictors of survival. Compared with no surgery, there was a significant 66% decreased risk of dying from overall cause of death (adjusted hazard ratio, AHR = 0.34, 5% Confidence Interval, CI = 0.26-0.46), and significant 51% decreased risk of dying from cervical cancer-specific cause, AHR = 0.41, 95% CI, 0.28-0.58, for women who received radical surgery. There was a dose-response effect between tumor stage at diagnosis and survival. Relative to women who were diagnosed with stage I tumor (early stage), those who were diagnosed at stage IV (late stage) were almost three times as likely to die from overall cause (AHR = 2.78, 95% CI, 2.24 – 3.45), as well as two times as likely to die from cancer-specific cause, AHR = 2.28, 95% CI, 1.76 – 2.29. The risk of dying also significantly increased with advancing age. Conclusion: There was no racial/ethnic variance in overall and \u0000cervical cancer-specific survival among older US women but \u0000survival was significantly influenced by treatment received tumor stage at diagnosis and age at diagnosis. \u0000 \u0000Keywords: Cervical carcinoma; Race/ethnicity; Income; \u0000Histopathology; Survival.","PeriodicalId":93450,"journal":{"name":"International journal of health research and innovation","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89906251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge, attitude and provision of emergency contraception among health professionals in Borno state northern Nigeria","authors":"A. Geidam, A. Kullima, G. Sadiq","doi":"10.4314/IJHR.V2I4.55433","DOIUrl":"https://doi.org/10.4314/IJHR.V2I4.55433","url":null,"abstract":"Purpose: To determine the knowledge, attitudes and \u0000provision of emergency contraception among health \u0000professional’s (physicians, pharmacist and nurse/midwives) in Borno State in northern Nigeria. \u0000Methods: A validated self administered questionnaires \u0000issued to randomly selected physicians, pharmacist and \u0000nurses/midwives. The questionnaire enquired about \u0000knowledge, attitudes and provision of emergency \u0000contraception. Results: Overall awareness about emergency contraception is 80.6% among the health professionals, but was lower among nurse/midwives (69.8%). The awareness of the various methods of emergency contraceptives was poor, with only 97 (49.5%) of the respondent aware of Estrogen as a method and only 10(5.1%) knows that Danazol can be use for \u0000emergency contraception. In 20 (10.2%) of the cases the \u0000respondent were not sure of the correct timing of EC. Only 71 (36.2%) of the respondents had ever provided EC before. Among the professional groups, physicians were more likely to approve the use while pharmacists were more likely to have provided EC before. Conclusion: Although the awareness of emergency contraception among health care providers in Borno State is high, its provision and the knowledge of the various methods \u0000are poor. There is the need of re-educating our health \u0000professionals on emergency contraception. \u0000 \u0000Keywords: Emergency contraception, Health professionals, \u0000Knowledge, Attitude","PeriodicalId":93450,"journal":{"name":"International journal of health research and innovation","volume":"411 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79887451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Ude, O. Akinwal, C. Ukaga, M. Ajayi, D. Akand, P. Gyang, M. Adeleke, A. Dike
{"title":"Prevalence of urinary Schistosomiasis in Umuowele, Agulu community, Anambra state, Nigeria","authors":"E. Ude, O. Akinwal, C. Ukaga, M. Ajayi, D. Akand, P. Gyang, M. Adeleke, A. Dike","doi":"10.4314/IJHR.V2I4.55435","DOIUrl":"https://doi.org/10.4314/IJHR.V2I4.55435","url":null,"abstract":"Purpose: To apply molecular techniques in producing a \u0000proper data on the prevalence of urinary schistosomiasis in Umuowele community located around Agulu Dam, Southwest Nigeria. Methods: Urine samples from 108 pupils were screened for schistosomiasis using haematuria and polymerase chain reaction (PCR) amplification of schistosome Dra1 repeat. Six snails collected from the human-water contact site in the lake were also screened for schistosome infection by PCR \u0000amplification of the Dra1 repeat while PCR-Restriction \u0000Fragment Length Polymorphism (PCR-RFLP) was used for \u0000snail species identification. Results: Haematuria revealed 48.1% prevalence rate among the pupils while PCR showed 58.3%. Three snails were also positive for schistosome infection one of which was identified \u0000as Bulinus truncatus while the other two belonged to the \u0000genus, Physa. Conclusion: There was a high prevalence of S. haematobium infection among the participants. PCR was able to detect infection in cases otherwise shown to be negative by haematuria, thereby making it possible for all the infected participants to receive treatment. Bulinus truncatus is one of the snails which may be responsible for the transmission of urinary schistosomiasis in the community. \u0000 \u0000Keywords: Bulinus truncatus, Schistosoma haematobium, \u0000PCR-RFLP, schistosome infection.","PeriodicalId":93450,"journal":{"name":"International journal of health research and innovation","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75794305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toxicological profiles of commercial herbal preparation, Jobelyn","authors":"J. Eniojukan, B. Aina","doi":"10.4314/IJHR.V2I4.55438","DOIUrl":"https://doi.org/10.4314/IJHR.V2I4.55438","url":null,"abstract":"PURPOSE: Jobelyn® is a commercial herbal product \u0000recommended for the management of anemia related \u0000illnesses. Despite its wide use, there is limited report on its toxicological profile. This study examined the acute and shortterm chronic toxicity profiles of the product with emphasis on the LD50, gross morphological and histopathological effects. METHODS: Albino mice (mean weight: 16.45±3.14g) were used in this study. For acute toxicity, graded concentrations of Jobelyn® were administered orally and intraperitoneally as single doses to the mice. Intraperitoneal administration of sub-lethal doses daily for 14 days was adopted for the shortterm \u0000chronic toxicity studies. RESULTS: The LD50 following oral and intraperitoneal administration were 215.06 mg/kg (r = 0.916) and 193.37 mg/kg (r = 0.995), respectively. The major behavioral/ morphological effects at high doses were reduction in motor activity, piloerection and sedation. The sub-lethal doses did not significantly modify the normal behavioral repertoire of licking, grooming and sniffing. Histopathological examination also did not indicate severe pathological changes. At the lethal doses, some degree of congestion was noticed in the lung, liver splenic and kidney tissues. Short-term chronic studies did not produce further toxic effects but transient mild \u0000sedation and piloerection and histopathological examination revealed only mild congestion in the organs. No death of the animals was recorded during the period of sub-chronic toxicity assessment. CONCLUSION: Jobelyn® is likely to be safe for use in humans when administered at recommended doses. \u0000 \u0000Keywords: Jobelyn, safety profile, LD50, toxicity","PeriodicalId":93450,"journal":{"name":"International journal of health research and innovation","volume":"205 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79777917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Smith, M. Bamidele, H. Goodluck, M. Fowora, A. Emmanuel, Omonigbehin, B. Opere, O. Aboaba
{"title":"Antimicrobial susceptibilities of salmonellae isolated from food handlers and cattle in Lagos, Nigeria","authors":"S. Smith, M. Bamidele, H. Goodluck, M. Fowora, A. Emmanuel, Omonigbehin, B. Opere, O. Aboaba","doi":"10.4314/IJHR.V2I2.55421","DOIUrl":"https://doi.org/10.4314/IJHR.V2I2.55421","url":null,"abstract":"Purpose: Food handlers play an important role in the \u0000transmission of typhoid bacilli and other Salmonella spp. This study was conducted to determine the prevalence and antimicrobial resistance patterns of Salmonella spp. from food handlers and cattle and compare the patterns with specimens from patients. Methods: A total of 206 stool samples from apparently healthy food handlers from bukkas (cafeteria) and 100 stool samples from cattle were collected in Lagos Metropolis between June 2006 and June 2007. The prevalence and susceptibility patterns of the S. typhi isolates from the samples and those obtained from the stool samples of 27 patients were determined. \u0000Results: Salmonella species isolated from the stool samples collected from food handlers were S. typhi, S. enteritidis, S. choleraesuis, S. paratyphi A and S. arizona with prevalence of 6.8%, 5.3%, 2.9%, 1.5% and 0.5%, respectively. S. enteritidis and S. typhimurium were isolated from 100 faecal cattle samples with prevalence of 12% and 3%, respectively. Nearly all the isolates (including the clinical isolates) were sensitive to nitrofurantoin, nalidixic acid, and ofloxacin, while \u0000all were sensitive to ciprofloxacin. Conclusion: Food handlers working in bukkas (cafeteria) and cattle are possible reservoirs of Salmonalle species in Lagos. Other than fluoroquinolones, Salmonalle species exhibit high levels of resistance to most antibiotics. \u0000 \u0000Keywords: Salmonella species; Food handlers; Cattle, \u0000Antibiotic resistance; Lagos.","PeriodicalId":93450,"journal":{"name":"International journal of health research and innovation","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78101972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Success of the Control of Tuberculosis in Nigeria: A Review","authors":"P. Erah, W. Ojieabu","doi":"10.4314/IJHR.V2I1.55382","DOIUrl":"https://doi.org/10.4314/IJHR.V2I1.55382","url":null,"abstract":"Tuberculosis (TB) has emerged as the single leading cause of death from any single infectious agent and has continued to be a major public health problem all over the world. Of the over 14 million cases worldwide reported by World Health Organisation (WHO) in 2008, Nigeria ranked fifth in terms of incidence. Depending on the prevailing social factors such as socioeconomic status of the people, malnutrition, crowded living conditions, incidence of HIV/AIDS, level of development of health infrastructures, quality of available control programmes, degree of drug resistance to anti-tuberculous agents, etc, prevalence, patterns of presentation, and outcomes of treatment from TB can vary from one country to another and from one region of a country to the other. Attempts to deal with \u0000the problems of the disease led to the development of Directly Observed Treatment Short Course (DOTS) by WHO in 1995, and more recently the Stop TB strategy in 2006. In Nigeria, the DOTS programme has been implemented in all States and local government areas in the country and 3,000 DOTS centres have been operating across the country since 2006. This article reviewed the available information on the success of the control of TB in Nigeria has observed a significant improvement in TB detection and treatment. However, neither the set target \u0000for the detection rate nor the cure rate have been achieved nationally as several challenges have militated against the effective implementation of the DOTS programme. \u0000 \u0000Keywords: Tuberculosis control, treatment success, DOTS \u0000programme, Stop TB strategy.","PeriodicalId":93450,"journal":{"name":"International journal of health research and innovation","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82440277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sexual practices and knowledge about Hiv/aids among Nigerian secondary school students","authors":"T. Ola, B. Oludare","doi":"10.4314/IJHR.V1I4.55377","DOIUrl":"https://doi.org/10.4314/IJHR.V1I4.55377","url":null,"abstract":"PURPOSE: A cross-sectional survey was conducted among \u0000secondary school students in Ekiti State, Nigeria to determine their knowledge about HIV/AIDS, sexual practices and their sources of information. METHODS: Using a self-administered questionnaire, 779 randomly selected students, aged 12 yr and above, attending 10 secondary schools from five Universal Basic Education (UBE) Local Government Areas in Ekiti State, Nigeria were surveyed to determine their knowledge about HIV/AIDS, sexual practices and their sources of information. The data collected were analysed using SPSS version 14. \u0000RESULTS: Majority of the respondents across the classes \u0000(99.4%) were knowledgeable about the modes of transmission of HIV/AIDS. In spite of this, they still engaged in risky sexual practices like having casual sex, multiple sexual partners, nonuse of condom and having sex for economic reasons. Most of the students in the exit classes acquired information about some sexual practices like oral sex from the Internet. CONCLUSION: Although there appears to be adequate knowledge about HIV/AIDS among youths, risky sexual practices are still common. Developing, restructuring and strengthening HIV/AIDS risk reduction interventions are highly recommended. \u0000 \u0000Key Words: Adolescents; Sexual practices; knowledge of \u0000HIV/AIDS.","PeriodicalId":93450,"journal":{"name":"International journal of health research and innovation","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89486737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A 6-month review of medical admissions in a nigerian teaching hospital","authors":"O. Akoria, E. Unuigbe","doi":"10.4314/IJHR.V2I2.55402","DOIUrl":"https://doi.org/10.4314/IJHR.V2I2.55402","url":null,"abstract":"Purpose: To provide an overview of morbidity and mortality in the medical wards of a teaching hospital and to generate discussions among staff members with a view to improving patient outcomes and data handling. \u0000Methods: A retrospective survey of admissions and \u0000mortalities in the medical wards of the University of Benin \u0000Teaching Hospital was undertaken from 1st January to 30th June 2006, using ward Record and Change books, and copies of death certificates. Morbidity data were assessed for two medical wards and mortalities for all medical admissions within the period under review were evaluated. Results: Health information was managed entirely manually. Data sources were quite often inaccessible or mutilated, and the utility of available data was limited by incomplete and incorrect documentation. No clinical coding of morbidities or mortalities was available. Human immunodeficiency virus (HIV) infection and its complications accounted for significantly more female than male admissions (26.1% and 16.2% respectively; p=0.005), and for more female than male \u0000deaths (34.6% and 29.6% respectively; p< 0.0001). Most \u0000deaths occurred between midnight and the start of the \u0000working day, with a second peak during prime working hours. Conclusions: Less than optimal health information \u0000management was apparent in the health facility studied. \u0000Mortality among the patients was highest in HIV-infected \u0000patients than other diseases. Capacity building and \u0000appropriate infrastructural development is required to improve the management of vitally important health information. \u0000 \u0000Keywords: Health information; Morbidity; Mortality; Medical \u0000Wards; Nigeria.","PeriodicalId":93450,"journal":{"name":"International journal of health research and innovation","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76641263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Biadgilign, A. Deribew, A. Amberbir, Kebede Deribe, A. Berhane
{"title":"Discordance Between Providers Estimated and Caregivers Self Reported Adherence to HAART and Immunological Response Among HIV Infected Children in Ethiopia","authors":"S. Biadgilign, A. Deribew, A. Amberbir, Kebede Deribe, A. Berhane","doi":"10.4314/IJHR.V2I2.55405","DOIUrl":"https://doi.org/10.4314/IJHR.V2I2.55405","url":null,"abstract":"Purpose: Poor concordance between patient and physician \u0000reports of adherence might lead to inappropriate decisions \u0000regarding therapy. This study was undertaken to determine the rate of discordance between caregivers of children and physicians on adherence to Highly Active Antiretroviral Therapy (HAART). Methods: In a cross sectional study involving 390 respondents that was conducted in five hospitals in Addis Ababa, agreement between caregiver-reported adherence and providers’ estimate of adherence was compared using Kappa (k) statistic. The association between the CD4 counts \u0000and measure of adherence was evaluated using a receiver \u0000operating characteristic (ROC) curve. Results: Caregivers reported dose adherence was 87% in the last 7 days and physician estimated 84% of the children as adherent based on their judgment. Fair agreement was observed between caregivers-reported dose adherence and \u0000providers' estimate adherence (Kappa = 0.27, p=0.0001). In a ROC curve, the association between a current CD4 count slope and physician estimated was poor. \u0000Conclusions: There is fair agreement and high rate of \u0000discordance (18%) between physicians estimated and \u0000caregivers reported adherence. These recall for an \u0000intervention to augment better mutual understanding between physicians and caregivers on the issue of adherence to HAART under clinical care programme. \u0000 \u0000Keywords: Adherence; CD4 count; Discordance; HAART.","PeriodicalId":93450,"journal":{"name":"International journal of health research and innovation","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80835670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence and Awareness about Chlamydial Infection in Women Undergoing Infertility Evaluation in Lagos, Nigeria","authors":"O. Oloyede, T. Fakoya, A. Oloyede, A. Alayo","doi":"10.4314/IJHR.V2I2.55412","DOIUrl":"https://doi.org/10.4314/IJHR.V2I2.55412","url":null,"abstract":"Purpose: To determine the prevalence and level of \u0000awareness of genital Chlamydia trachomatis infection and \u0000possible correlative factors among women undergoing \u0000infertility evaluation. Methods: The study involved analysis of demographics and results of chlamydia screening in 77 infertile women undergoing evaluation over a six month period in Lagos, Nigeria. Results: The mean age was 32 + 6.4 yr (range 20-39 yr). Chlamydia screening was positive in 14 (18.2%). Awareness about the existence, symptomatology, mode of infection and complications was poor. Statistically significant correlation existed between prevalence of chlamydia infection and age, previous history of sexual infection and minimum of one sexual partner in the last one year (p <0.05). The prevalence also increased in secondarily infertile and married women. Conclusion: Chlamydia prevalence was relatively high in women undergoing infertility evaluation in Lagos, with positive correlative factors being increasing age of women, previous sexual infection and one or more sexual partners. \u0000 \u0000Keywords: Prevalence; Awareness; Chlamydial infection \u0000screening; Infertility; Nigeria.","PeriodicalId":93450,"journal":{"name":"International journal of health research and innovation","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77496563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}