Journal of medical case reports and reviews最新文献

{"title":"Symptomatic and radiological response to 177-Lu-DOTATE treatment of a neuroendocrine tumor of the rectum with liver metastasis: Case report","authors":"Mariana Ferrari de Jesus Abdalla, Giselle Almeida, Hézio Jadir Fernandes Júnior","doi":"10.15761/mcrr.1000139","DOIUrl":"https://doi.org/10.15761/mcrr.1000139","url":null,"abstract":"The present report describes a case of a neuroendocrine tumor of the rectum with liver metastasis in a 35-year-old woman. The rectum is the second most common location of gastrointestinal neuroendocrine tumors and is typically diagnosed through a screening colonoscopy finding for non-tumor related symptoms. Surgical treatment is indicated when the disease is localized, but due to its characteristics, in most cases, this cancer is diagnosed in advanced stages. When the tumor is advanced and/or metastasis is present, therapeutic options include embolization, somatostatin analogs, interventional radiology, chemotherapy, and radiometabolic peptide therapy. 177-Lutecio-DOTATE therapy has a positive impact on the quality of life of patients with inoperable metastatic tumors. The patient described in the case was initially treated with surgery and chemotherapy and later with liver segmentectomies, embolization, and octreotide due to liver tumor recurrence. With the persistence of the metastasis, she started treatment with 177-Lutecio-DOTATE, and saw, after the second cycle of administration, partial remission of the tumor. This case describes how 177-Lutecio-DOTATE is a viable treatment option and has shown significant results in inoperable and/or metastatic disease. *Correspondence to: Mariana Ferrari de Jesus Abdalla, Santo Amaro University (UNISA) and Cancer Institute Arnaldo Vieira de Carvalho, Brazil, E-mail: mari_ ferrari90@hotmail.com","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81992837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kindler syndrome: A very rare bullosa poikyloderma discovered in a baby","authors":"K. Elboukhari, S. Elloudi, H. Baybay, F. Mernissi","doi":"10.15761/mcrr.1000144","DOIUrl":"https://doi.org/10.15761/mcrr.1000144","url":null,"abstract":"Kindler syndrome is a very rare bullous dermatosis of the childhood. It is classified as a subtype of epidermolyse bullosa and is characterized by the occurrence of acral predisposing blisters, associated to poikyloderma, skin atrophy and photosensitivity. It may be sporadic or transmitted in an autosomic recessive model. The treatment is preventive and symptomatic. The aim of this article is to describe this syndrome, and explain its pathogeny via a case presentation with a literature review. *Correspondence to: Khadija Elboukhari, Departement of Dermatology, University Hospital of Fez, Morocco, E-mail: elboukharikhadija89@gmail.com","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83217877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Syndrome of Inappropriate Antidiuretic Syndrome (SIADH) in association with Riluzole and SSRI treatment in an ALS patient","authors":"Efrat Zamir, Talia Alster, R. Farah","doi":"10.15761/mcrr.1000123","DOIUrl":"https://doi.org/10.15761/mcrr.1000123","url":null,"abstract":"","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"115 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85288887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute interstitial nephritis due to Ciclosporin a toxicity during Behçet's disease","authors":"S. SalemBouomrani, Nesrine Regaïeg, M. Nefoussi, S. Trabelsi","doi":"10.15761/MCRR.1000125","DOIUrl":"https://doi.org/10.15761/MCRR.1000125","url":null,"abstract":"Introduction : Ciclosporin A is an immunosuppressive molecule widely used in Behçet’s disease (BD), especially for severe ocular and/or neurological disorders. Its particular toxicity in this field has, however, largely limited its use during this vasculitis. We report an aspect. Case report : 26-year-old patient followed since the age of 20 for BD with severe ocular involvement (bilateral posterior steroid-resistant uveitis with a significant decrease in visual acuity) requiring treatment with Ciclosporin A at a dose of 5mg/kg/twice daily during the first month and then 5mg/kg/day as a maintenance dose to control uveitis. The one-year control report noted a creatinine at 147μmol/l with aseptic leucocyturia at 400 elements/l. blood pressure was normal and there was no associated hematuria or proteinuria. The infectious and toxic investigation was normal. The ultrasound showed two kidneys of normal size and echo-structure. Renal biopsy revealed acute interstitial nephritis with images of toxic tubular necrosis. Cyclosporine was discontinued and replaced with azathioprine. Renal function normalized three weeks after stopping the molecule. Conclusion : periodic and regular monitoring of renal function (blood and urine tests) is strongly recommended in order to detect renal damage early in the BD; especially if Ciclosporin A treatment.","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88974697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudo-cannon ball presentation, a chest radiograph pitfall","authors":"A. Alfahad, Marawan Elfarargy","doi":"10.15761/mcrr.1000132","DOIUrl":"https://doi.org/10.15761/mcrr.1000132","url":null,"abstract":"Multiple pulmonary opacities on chest radiographs, often construed as cannon balls, are the classical presentation of haematogenous dissemination of malignancy to lungs. In contrast, such presentation may be associated with a non-malignant, extra-pulmonary aetiology. Thus, such radiographs require meticulous interpretation. We present a case report of a young patient who suffered from spontaneous rib fractures, mimicking cannon balls appearance with a review of literature. Conclusion: Attention to past medical history coupled with recognising the cannonball like pattern on chest radiographs is paramount in order to reach the most likely diagnosis. *Correspondence to: Aws Alfahad, Consultant Interventional Radiologist, Radiology Clinical Tutor and Specialty lead, The Pennine Acute Hospitals Trust, Northern Care Alliance Manchester, UK, E-mail: drawsalfahad@yahoo.com","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79975206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anaesthesia for obstructive symptomatic retrosternal goiter requiring hemithyroidectomy – a case report","authors":"Noortje Wismans, E. Bouman","doi":"10.15761/MCRR.1000133","DOIUrl":"https://doi.org/10.15761/MCRR.1000133","url":null,"abstract":"Retrosternal thyroid enlargement is a challenging issue in anaesthesia because it may cause respiratory and hemodynamic compromise by obstructing the trachea or vascular structures. In this case report we present the anaesthetic management for hemithyroidectomy in an 83 year old female with stridor and dyspnoea caused by obstructing retrosternal goiter, focussing on the necessity of multidisciplinary approach and the airway strategy using venovenous extracorporeal membrane oxygenation as backup method.","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72828581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colorectal cancer conventional radiotherapy treatment technique with sparing the testicles","authors":"H. Osmić, S. Fazlić, E. Dedovic","doi":"10.15761/mcrr.1000120","DOIUrl":"https://doi.org/10.15761/mcrr.1000120","url":null,"abstract":"Colorectal cancer was the third most common cancer in 2012, with higher percentage of incidence in less developed countries. In a less developed countries usually conventional radiotherapy technique is used for treatment of colorectal cancer. Using this technique testicles receive a dose from scattered radiation, due to the divergence of fields towards the testicles. We tried to re-duce a testicular dose avoiding the divergence of fields towards the testicles. For that aim 28 mail patients (mean age 51.8 years), treated with 45 Gy using the conventional 3 field technique were selected and subjected to retrospective dosimetric study using the avoiding divergence technique. Significant statistical difference was showed between the two proposed techniques (5.66 Gy, 3.53 Gy; p <0.0001) in favour of avoiding divergence technique (median of the min-imum doses to the testicles: 0.20 Gy, 0.09 Gy and the median of the maximum doses to the testicles: 15.32 Gy, 14.00 Gy). Patients with rectal cancer who are going to receive radiotherapy treatment with conventional radiotherapy tech-nique, are at risk of permanent infertility. This paper presents conventional ra-diotherapy technique, for the patients with rectal cancer which will, due to re-duction of medium testicular dose, reduce the risk of infertility. *Correspondence to: Edis Dedovic, Depertment of medical physics and radiation protection, University Clinical Centre Tuzla, Ul. prof. dr. Ibre Pašića, Tuzla 75000, Bosnia and Herzegovina, Tel: +38761675094; E-mail: edis.djedovic@yahoo.com","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"148 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86077130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coprophagia in an older adult with Schizophrenia- A case report and brief review","authors":"Hardeep Jaspal, D. Neupane, S. Madhusoodanan","doi":"10.15761/mcrr.1000135","DOIUrl":"https://doi.org/10.15761/mcrr.1000135","url":null,"abstract":"Background: Coprophagia, the act of consuming one’s own feces is a rare symptom of certain neurological or psychiatric disorders including pica, mental retardation, seizure disorder, cerebral atrophy and tumors, alcoholism, depression, obsessive compulsive disorder, schizophrenia, delirium, and dementia. Coprophagia is difficult to treat and distressing for the caregiver. It can lead to complications including salivary infections, parasitic infestations, and even death. Method: A 63-year-old man with history of schizophrenia was admitted to the psychiatric unit for aggressive and disorganized behavior. He was treated with multiple psychotropics including aripiprazole, mirtazapine, quetiapine, lorazepam, and risperidone over a course of four weeks. Results: The Clinical Global Impression (CGI) severity score at baseline was markedly ill (5). Initial CGIimprovement score after a week was much worse (6). The CGI-I worsened to very much worse (7). After introduction of quetiapine in 1 weeks’ time, patient’s CGI-I improved to minimally improved (3), and at discharge after 6 weeks, to much improved (2), indicating significant improvement. Conclusion: Coprophagia is a difficult to treat and is a distressing symptom. Treatment with quetiapine appears to have helped our patient. There is paucity of published studies and future large scale studies with medication and other behavioral interventions are recommended. *Correspondence to: Subramoniam Madhusoodanan, Department of Psychiatry, St. John’s Episcopal Hospital, 327 Beach 19th Street, Far Rockaway, NY 11691, USA, E-mail: sdanan@ehs.org Received: August 29, 2019; Accepted: September 30, 2019; Published: October 04, 2019 Introduction Coprophagia is the act of consuming one’s own feces and is a relatively rare symptom associated with neurological or psychiatric disorders. This behavior can be associated with multiple psychiatric and medical conditions. Although it has been reported as a symptom primarily associated with pica [1], mental retardation [2], and new-onset psychiatric conditions [3], coprophagia can be seen in other medical disorders including seizure disorders, cerebral atrophy, and tumors [4]. Furthermore, psychiatric disorders associated with coprophagia include alcoholism, depression, obsessive-compulsive disorder, schizophrenia, fetishes, delirium, and dementia [4]. Addressing the underlying cause and treatment of coprophagia is important as it can lead to oral and salivary infections, gastrointestinal parasitic infestations, and even death. This behavior is also difficult to manage for nursing staff and other caregivers in facilities, as there is very little information about the treatment protocol. There have been few reports on coprophagia in schizophrenic patients. Distinguishing coprophagia as a symptom of an underlying comorbidity from symptoms of patient’s psychosis is important for determining the best course of treatment. The current literature describes a few strategies that hav","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79043151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute closure of the left anterior descending artery in a young patient with suspicion of past Kawasaki disease during childhood - A case study","authors":"O. M., M. A., D. M.","doi":"10.15761/mcrr.1000126","DOIUrl":"https://doi.org/10.15761/mcrr.1000126","url":null,"abstract":"","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88682106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behcet disease presenting initially as isolated recurrent aphthous ulcers only: A case report","authors":"D. Okoh, Pedro Emualosi, Isaac Izevbigie, M. Okoh","doi":"10.15761/mcrr.1000117","DOIUrl":"https://doi.org/10.15761/mcrr.1000117","url":null,"abstract":"","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"110 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89028537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}