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Treatment of Dorsal Back Pain with Glucopuncture 葡萄糖穿刺治疗背背部疼痛
Journal of medical case reports and reviews Pub Date : 2021-01-01 DOI: 10.15761/mcrr.1000167
Jan Kersschot
{"title":"Treatment of Dorsal Back Pain with Glucopuncture","authors":"Jan Kersschot","doi":"10.15761/mcrr.1000167","DOIUrl":"https://doi.org/10.15761/mcrr.1000167","url":null,"abstract":"In the last decades, glucose 5% injections have gained more interest [1-3]. Some have even compared its effectiveness to corticosteroid injections [4]. To bring more attention to this new technique, the term Glucopuncture was introduced in January 2021. Glucopuncture is a medical procedure which applies isotonic glucose injections for the management of non-rheumatic musculoskeletal conditions [5]. The technique consists of multiple injections of G5W (Glucose 5% in Water) in the region of complaint. Intradermal injections are given for pain modulation, intralesional injections are given in, for example, muscles, tendons, and ligaments to stimulate tissue repair. One can also apply these injections adjacent to peripheral nerve endings [6] or in the epidural space [7]. In this case report, both intradermal and intraligamentous injections were applied.","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75642733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Pneumopericardium, pneumothorax, and pulmonary hemorrhage from invasive pulmonary aspergillosis. A case report 侵袭性肺曲霉病引起的心包、气胸和肺出血。病例报告
Journal of medical case reports and reviews Pub Date : 2021-01-01 DOI: 10.15761/MCRR.1000151
Billy C. Wang, Richard P Lion, H. Chandnani
{"title":"Pneumopericardium, pneumothorax, and pulmonary hemorrhage from invasive pulmonary aspergillosis. A case report","authors":"Billy C. Wang, Richard P Lion, H. Chandnani","doi":"10.15761/MCRR.1000151","DOIUrl":"https://doi.org/10.15761/MCRR.1000151","url":null,"abstract":"Pneumopericardium is a rare condition with etiologies including adjacent infection, pathology, or trauma. Invasive pulmonary aspergillosis occurs almost exclusively in immunocompromised patients and may be associated with pneumopericardium. We present a 12-year-old female with acute lymphoblastic leukemia who developed multifocal pulmonary Aspergillus terreus after induction chemotherapy and prolonged granulocytopenia. Despite aggressive antifungal therapy, she developed pneumopericardium, which progressed to pneumothorax and pulmonary hemorrhage, resulting in death. To our knowledge, no reports involving the sequential development of these three findings are reported to date. Unusual to her case was the development of pneumopericardium without fistula or direct evidence of Aspergillus pericarditis.","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76176360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is there a role for the Girdlestone resection arthroplasty in modern orthopedic trauma surgery? Case series from a medically underserved region and literature review Girdlestone关节置换术在现代骨科创伤手术中是否有一席之地?来自医疗服务不足地区的病例系列和文献综述
Journal of medical case reports and reviews Pub Date : 2021-01-01 DOI: 10.15761/MCRR.1000161
Ngongalah Suhfube Stephane, V. Neuhaus, Slobodan Mirosavljev, B. Ciritsis
{"title":"Is there a role for the Girdlestone resection arthroplasty in modern orthopedic trauma surgery? Case series from a medically underserved region and literature review","authors":"Ngongalah Suhfube Stephane, V. Neuhaus, Slobodan Mirosavljev, B. Ciritsis","doi":"10.15761/MCRR.1000161","DOIUrl":"https://doi.org/10.15761/MCRR.1000161","url":null,"abstract":"Three cases of proximal femoral fractures due to gunshot wounds were treated with Girdlestone resection arthroplasty. A preoperative functional evaluation and a one year postoperative follow up was performed using the Merle d’Aubigne Score. Despite the unavailability of osteosynthesis or prosthetic implant a good functional result was achieved. The established surgical procedure of Girdlestone resection arthroplasty represents an effective treatment option for patients with severe fractures of the proximal femur with a high risk of infection, who live in low socio-economic and medically underserved areas. This procedure avoids secondary surgery, chronic infections, fistulas and repeated hospitalization. As a definitive treatment in the geopolitical and surgical setting mentioned, this is a previously undescribed application of the Girdlestone resection arthroplasty.","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91377676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular insights into the docking of N-palmitoyl serine (Palmi-Ser) interaction with the nuclear receptor subfamily 4 group A member 2 (NR4A2): Effect of Palmi-Ser on survival rate in the Drosophila model of Parkinson's disease n -棕榈酰丝氨酸(Palmi-Ser)与核受体亚家族4组A成员2 (NR4A2)相互作用对接的分子见解:Palmi-Ser对帕金森病果蝇模型存活率的影响
Journal of medical case reports and reviews Pub Date : 2021-01-01 DOI: 10.15761/mcrr.1000173
Y. Nakagawa-Yagi, Takaki Nedachi, Haruhisa Kawasaki, Takahiro Yamaguchi, Enzo Kawasaki, A. Hara, H. Hara, N. Ishida
{"title":"Molecular insights into the docking of N-palmitoyl serine (Palmi-Ser) interaction with the nuclear receptor subfamily 4 group A member 2 (NR4A2): Effect of Palmi-Ser on survival rate in the Drosophila model of Parkinson's disease","authors":"Y. Nakagawa-Yagi, Takaki Nedachi, Haruhisa Kawasaki, Takahiro Yamaguchi, Enzo Kawasaki, A. Hara, H. Hara, N. Ishida","doi":"10.15761/mcrr.1000173","DOIUrl":"https://doi.org/10.15761/mcrr.1000173","url":null,"abstract":"","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89296709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How to assess IOP Peak and its Importance in Glaucoma Management 如何评估眼压峰值及其在青光眼治疗中的重要性
Journal of medical case reports and reviews Pub Date : 2021-01-01 DOI: 10.15761/mcrr.1000174
Remo Susanna Jr, F. Susanna, C. Susanna, Bianca N. Susanna
{"title":"How to assess IOP Peak and its Importance in Glaucoma Management","authors":"Remo Susanna Jr, F. Susanna, C. Susanna, Bianca N. Susanna","doi":"10.15761/mcrr.1000174","DOIUrl":"https://doi.org/10.15761/mcrr.1000174","url":null,"abstract":"Elevated intra-ocular pressure (IOP) and mean IOP are considered the main risk factors for the development and progression of glaucoma. However, some patients still progress with IOP apparently in the target range. This observation has been explained on the basis that other non-IOP dependent risk factors are contributing to the glaucoma pathogenesis in these individuals. An alternative explanation is that progression occurs at least in - part due to high IOP peaks not detected during routine eye examinations. Several studies have demonstrated that peak IOP may be a better predictor of glaucoma progression. IOP peak assessment has been used recently to verify if the peak pressure of a given patient is in target range, to evaluate glaucoma suspect risk, the efficacy of hypotensive drugs and to detect early loss of IOP control. These are important aims to be addressed in glaucoma management. Several methods have been described to assess IOP peaks. The costs and labor involved in this make the determination of the 24-hour IOP or contact lens-sensor are difficult if not impossible in all patients. Recently the water drinking test (WDT) has been used as a surrogate marker for outflow reserve to detect IOP instability and to estimate IOP peak pressure. Peak IOP elicited by this test may be an indicator for the likelihood of progression and efficacy of hypotensive drugs the aim this manuscript is to present the importance of detecting IOP peaks in glaucoma management.","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76481415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bowen’s disease of the anal canal treated with radiation therapy: A case report 放射治疗肛管Bowen病1例
Journal of medical case reports and reviews Pub Date : 2021-01-01 DOI: 10.15761/mcrr.1000169
M. I, R. N., Touimi Sh, E. S, K. T, E. H, B. N
{"title":"Bowen’s disease of the anal canal treated with radiation therapy: A case report","authors":"M. I, R. N., Touimi Sh, E. S, K. T, E. H, B. N","doi":"10.15761/mcrr.1000169","DOIUrl":"https://doi.org/10.15761/mcrr.1000169","url":null,"abstract":"","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83880035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ANTIPROLIFERATIVE PROPERTIES OF ETHANOLIC AND AQUEOUS GRAVIOLA LEAF EXTRACTS ON TONGUE SQUAMOUS CELL CARCINOMA CELL LINE-25. 紫荆叶乙醇和水提物对舌鳞癌细胞系25的抗增殖作用。
Journal of medical case reports and reviews Pub Date : 2020-08-03 Epub Date: 2020-08-21 DOI: 10.15520/jmcrr.v3i08.201
Ricardo A Velázquez-Aponte, Céline Cassé
{"title":"ANTIPROLIFERATIVE PROPERTIES OF ETHANOLIC AND AQUEOUS GRAVIOLA LEAF EXTRACTS ON TONGUE SQUAMOUS CELL CARCINOMA CELL LINE-25.","authors":"Ricardo A Velázquez-Aponte,&nbsp;Céline Cassé","doi":"10.15520/jmcrr.v3i08.201","DOIUrl":"https://doi.org/10.15520/jmcrr.v3i08.201","url":null,"abstract":"<p><strong>Background: </strong><i>Annona muricata,</i> commonly known as Graviola, soursop or guanabana, is an evergreen tree native to the tropics with a long history of use in ethnomedicine in indigenous communities in Africa and South America. Its active phytoconstituents have provided medicinal benefits against various ailments and diseases such as arthritis, parasitic infection, hypertension, fever, or diabetes. Studies conducted <i>in vitro</i> and <i>in vivo</i> have concluded that Graviola phytocomponents have anti-cancer and anti-tumor properties. One of the characteristics of cancer cells is their uncontrolled proliferation rate. In that sense, molecules that inhibit cell proliferation offer potential therapeutical benefits.</p><p><strong>Methods: </strong>We prepared ethanolic and aqueous extracts from dried Graviola leaves and tested their respective antiproliferative activities on tongue Squamous Cell Carcinoma cell line-25. We treated the cells with increasing concentrations of the extracts for 24 h. The respective doses leading to a 50% inhibition of cells growth (GI<sub>50</sub>) were determined.</p><p><strong>Results: </strong>Our results showed that the ethanolic extract was 4 times more active in inhibiting the growth of Squamous Cell Carcinoma cell line-25 than the aqueous extract (respective GI<sub>50</sub> of 61.7 μg/mL, and 274.6 μg/mL).</p><p><strong>Conclusion: </strong>We hypothesize that some organic compounds involved in the antiproliferative/cytotoxicity of Graviola leaves were selectively extracted by Ethanol. Future plans include characterizing those bioactive compounds and assessing their activity on Squamous Cell Carcinoma cell line-25 vs. non-cancerous oral cells. Our hope is to discover natural molecules to be used as alternative treatments for oral Squamous Cell Carcinomas.</p>","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"3 8","pages":"749-755"},"PeriodicalIF":0.0,"publicationDate":"2020-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320751/pdf/nihms-1668384.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39266816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A strategy for rapidly making a vaccine and treatment for the disease caused by the Wuhan-Corona Virus 2019 (COVID19)-Part two 2019年武汉冠状病毒(covid - 19)引起的疾病的快速疫苗和治疗战略-第二部分
Journal of medical case reports and reviews Pub Date : 2020-01-01 DOI: 10.15761/mcrr.1000143
G. Pieczenik
{"title":"A strategy for rapidly making a vaccine and treatment for the disease caused by the Wuhan-Corona Virus 2019 (COVID19)-Part two","authors":"G. Pieczenik","doi":"10.15761/mcrr.1000143","DOIUrl":"https://doi.org/10.15761/mcrr.1000143","url":null,"abstract":"Presently, a majority of bioinformaticians analyze sequences by homology between the amino acid sequences of proteins. The assumption in this type of analysis is that if an identical nucleotide sequence codes for an identical peptide sequence in two different proteins in two different viruses; then, this is evidence of “descent from a common ancestor”. This is the Darwinian assumption and is the most common method of analysis. Just recently, for example, the following sequence VLLFLAFVV was identified as a common epitope in the Envelope protein (E) of both SARS and COVID19 [3] and they suggest this as the epitope for the basis of a vaccine. Their work is quite pretty. However, we feel that this may not be the best epitope on which to base a vaccine. We have two reasons. Firstly, this sequence is completely hydrophobic and that is rare in antibody-epitope interactions.","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76589578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Clinical reasoning in physiotherapy management of acute lumbar radiculopathy 急性腰椎神经根病物理治疗的临床分析
Journal of medical case reports and reviews Pub Date : 2020-01-01 DOI: 10.15761/mcrr.1000148
A. Smythe
{"title":"Clinical reasoning in physiotherapy management of acute lumbar radiculopathy","authors":"A. Smythe","doi":"10.15761/mcrr.1000148","DOIUrl":"https://doi.org/10.15761/mcrr.1000148","url":null,"abstract":"Lumbar radiculopathy is a common and debilitating condition with 30% of people affected experiencing pain and disability beyond 12 months. Physiotherapy is recommended as well as pain management as first line management in the absence of red flags, but due to the complex nature of the condition and the variety of causative factors and symptom presentations it can be difficult to treat. This case study describes in detail the clinical reasoning utilised to treat a common presentation of lumbar radiculopathy highlighting the complex and systematic thinking and decision making required to provide effective individualised treatment, reducing the likelihood of persistent pain and disability.","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86717433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pancreatic sarcomatoid carcinoma: An unusual evolution 胰腺肉瘤样癌:一种不寻常的演变
Journal of medical case reports and reviews Pub Date : 2020-01-01 DOI: 10.15761/mcrr.1000141
S. Omrani, M. Hajri, W. Ferjaoui, Rami Guizani, G. Talbi, L. Gharbi, R. Bayar, M. Khalfallah
{"title":"Pancreatic sarcomatoid carcinoma: An unusual evolution","authors":"S. Omrani, M. Hajri, W. Ferjaoui, Rami Guizani, G. Talbi, L. Gharbi, R. Bayar, M. Khalfallah","doi":"10.15761/mcrr.1000141","DOIUrl":"https://doi.org/10.15761/mcrr.1000141","url":null,"abstract":"Sarcomatoid carcinoma of the pancreas is a very rare pancreatic tumor that usually has a poor prognosis. However, we report here an exceptional case of long term evolution of this malignancy. The patient was a 73-year-old man who was operated of a sarcomatoid carcinoma of the pancreas 10 years ago. He received adjuvant chemotherapy with gemcitabine. Our patient was followed-up regularly. A routine check-up revealed that the patient was free of tumor recurrence and metastasis during 10 years. After this period of recovery, the patient presented a colonic obstruction due to a metastatic disease . Indeed, the early stage and the radical treatment may enhance the prognosis of sarcomatoid carcinoma. Also, this report demonstrates a rare presentation of pancreatic cancer with colonic metastatic obstruction.","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74416661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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