Colorectal cancer conventional radiotherapy treatment technique with sparing the testicles

H. Osmić, S. Fazlić, E. Dedovic
{"title":"Colorectal cancer conventional radiotherapy treatment technique with sparing the testicles","authors":"H. Osmić, S. Fazlić, E. Dedovic","doi":"10.15761/mcrr.1000120","DOIUrl":null,"url":null,"abstract":"Colorectal cancer was the third most common cancer in 2012, with higher percentage of incidence in less developed countries. In a less developed countries usually conventional radiotherapy technique is used for treatment of colorectal cancer. Using this technique testicles receive a dose from scattered radiation, due to the divergence of fields towards the testicles. We tried to re-duce a testicular dose avoiding the divergence of fields towards the testicles. For that aim 28 mail patients (mean age 51.8 years), treated with 45 Gy using the conventional 3 field technique were selected and subjected to retrospective dosimetric study using the avoiding divergence technique. Significant statistical difference was showed between the two proposed techniques (5.66 Gy, 3.53 Gy; p <0.0001) in favour of avoiding divergence technique (median of the min-imum doses to the testicles: 0.20 Gy, 0.09 Gy and the median of the maximum doses to the testicles: 15.32 Gy, 14.00 Gy). Patients with rectal cancer who are going to receive radiotherapy treatment with conventional radiotherapy tech-nique, are at risk of permanent infertility. This paper presents conventional ra-diotherapy technique, for the patients with rectal cancer which will, due to re-duction of medium testicular dose, reduce the risk of infertility. *Correspondence to: Edis Dedovic, Depertment of medical physics and radiation protection, University Clinical Centre Tuzla, Ul. prof. dr. Ibre Pašića, Tuzla 75000, Bosnia and Herzegovina, Tel: +38761675094; E-mail: edis.djedovic@yahoo.com","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"148 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of medical case reports and reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/mcrr.1000120","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Colorectal cancer was the third most common cancer in 2012, with higher percentage of incidence in less developed countries. In a less developed countries usually conventional radiotherapy technique is used for treatment of colorectal cancer. Using this technique testicles receive a dose from scattered radiation, due to the divergence of fields towards the testicles. We tried to re-duce a testicular dose avoiding the divergence of fields towards the testicles. For that aim 28 mail patients (mean age 51.8 years), treated with 45 Gy using the conventional 3 field technique were selected and subjected to retrospective dosimetric study using the avoiding divergence technique. Significant statistical difference was showed between the two proposed techniques (5.66 Gy, 3.53 Gy; p <0.0001) in favour of avoiding divergence technique (median of the min-imum doses to the testicles: 0.20 Gy, 0.09 Gy and the median of the maximum doses to the testicles: 15.32 Gy, 14.00 Gy). Patients with rectal cancer who are going to receive radiotherapy treatment with conventional radiotherapy tech-nique, are at risk of permanent infertility. This paper presents conventional ra-diotherapy technique, for the patients with rectal cancer which will, due to re-duction of medium testicular dose, reduce the risk of infertility. *Correspondence to: Edis Dedovic, Depertment of medical physics and radiation protection, University Clinical Centre Tuzla, Ul. prof. dr. Ibre Pašića, Tuzla 75000, Bosnia and Herzegovina, Tel: +38761675094; E-mail: edis.djedovic@yahoo.com
保留睾丸的结直肠癌常规放疗治疗技术
结直肠癌是2012年第三大常见癌症,在欠发达国家发病率更高。在欠发达国家,通常使用传统的放射治疗技术来治疗结直肠癌。使用这种技术,由于辐射场向睾丸发散,睾丸接受一定剂量的散射辐射。我们试图减少睾丸的剂量以避免电场向睾丸发散。为此,我们选择了28例使用常规3场技术接受45 Gy放射治疗的邮寄患者(平均年龄51.8岁),并采用避免发散技术进行回顾性剂量学研究。两种技术间差异有统计学意义(5.66 Gy, 3.53 Gy;p <0.0001)倾向于避免发散技术(睾丸最小剂量中位数:0.20 Gy, 0.09 Gy,睾丸最大剂量中位数:15.32 Gy, 14.00 Gy)。直肠癌患者在接受常规放射治疗后,存在永久不孕的风险。本文介绍了直肠癌患者的常规放射治疗技术,由于睾丸中剂量的减少,可以降低不育的风险。通讯:Edis Dedovic,乌尔图兹拉大学临床中心医学物理和辐射防护系。伊布雷博士Pašića,图兹拉75000,波斯尼亚和黑塞哥维那,电话:+38761675094;电子邮件:edis.djedovic@yahoo.com
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信