保留睾丸的结直肠癌常规放疗治疗技术

H. Osmić, S. Fazlić, E. Dedovic
{"title":"保留睾丸的结直肠癌常规放疗治疗技术","authors":"H. Osmić, S. Fazlić, E. Dedovic","doi":"10.15761/mcrr.1000120","DOIUrl":null,"url":null,"abstract":"Colorectal cancer was the third most common cancer in 2012, with higher percentage of incidence in less developed countries. In a less developed countries usually conventional radiotherapy technique is used for treatment of colorectal cancer. Using this technique testicles receive a dose from scattered radiation, due to the divergence of fields towards the testicles. We tried to re-duce a testicular dose avoiding the divergence of fields towards the testicles. For that aim 28 mail patients (mean age 51.8 years), treated with 45 Gy using the conventional 3 field technique were selected and subjected to retrospective dosimetric study using the avoiding divergence technique. Significant statistical difference was showed between the two proposed techniques (5.66 Gy, 3.53 Gy; p <0.0001) in favour of avoiding divergence technique (median of the min-imum doses to the testicles: 0.20 Gy, 0.09 Gy and the median of the maximum doses to the testicles: 15.32 Gy, 14.00 Gy). Patients with rectal cancer who are going to receive radiotherapy treatment with conventional radiotherapy tech-nique, are at risk of permanent infertility. This paper presents conventional ra-diotherapy technique, for the patients with rectal cancer which will, due to re-duction of medium testicular dose, reduce the risk of infertility. *Correspondence to: Edis Dedovic, Depertment of medical physics and radiation protection, University Clinical Centre Tuzla, Ul. prof. dr. Ibre Pašića, Tuzla 75000, Bosnia and Herzegovina, Tel: +38761675094; E-mail: edis.djedovic@yahoo.com","PeriodicalId":93315,"journal":{"name":"Journal of medical case reports and reviews","volume":"148 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Colorectal cancer conventional radiotherapy treatment technique with sparing the testicles\",\"authors\":\"H. Osmić, S. Fazlić, E. Dedovic\",\"doi\":\"10.15761/mcrr.1000120\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Colorectal cancer was the third most common cancer in 2012, with higher percentage of incidence in less developed countries. In a less developed countries usually conventional radiotherapy technique is used for treatment of colorectal cancer. Using this technique testicles receive a dose from scattered radiation, due to the divergence of fields towards the testicles. We tried to re-duce a testicular dose avoiding the divergence of fields towards the testicles. For that aim 28 mail patients (mean age 51.8 years), treated with 45 Gy using the conventional 3 field technique were selected and subjected to retrospective dosimetric study using the avoiding divergence technique. Significant statistical difference was showed between the two proposed techniques (5.66 Gy, 3.53 Gy; p <0.0001) in favour of avoiding divergence technique (median of the min-imum doses to the testicles: 0.20 Gy, 0.09 Gy and the median of the maximum doses to the testicles: 15.32 Gy, 14.00 Gy). Patients with rectal cancer who are going to receive radiotherapy treatment with conventional radiotherapy tech-nique, are at risk of permanent infertility. This paper presents conventional ra-diotherapy technique, for the patients with rectal cancer which will, due to re-duction of medium testicular dose, reduce the risk of infertility. *Correspondence to: Edis Dedovic, Depertment of medical physics and radiation protection, University Clinical Centre Tuzla, Ul. prof. dr. Ibre Pašića, Tuzla 75000, Bosnia and Herzegovina, Tel: +38761675094; E-mail: edis.djedovic@yahoo.com\",\"PeriodicalId\":93315,\"journal\":{\"name\":\"Journal of medical case reports and reviews\",\"volume\":\"148 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of medical case reports and reviews\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15761/mcrr.1000120\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of medical case reports and reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/mcrr.1000120","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

结直肠癌是2012年第三大常见癌症,在欠发达国家发病率更高。在欠发达国家,通常使用传统的放射治疗技术来治疗结直肠癌。使用这种技术,由于辐射场向睾丸发散,睾丸接受一定剂量的散射辐射。我们试图减少睾丸的剂量以避免电场向睾丸发散。为此,我们选择了28例使用常规3场技术接受45 Gy放射治疗的邮寄患者(平均年龄51.8岁),并采用避免发散技术进行回顾性剂量学研究。两种技术间差异有统计学意义(5.66 Gy, 3.53 Gy;p <0.0001)倾向于避免发散技术(睾丸最小剂量中位数:0.20 Gy, 0.09 Gy,睾丸最大剂量中位数:15.32 Gy, 14.00 Gy)。直肠癌患者在接受常规放射治疗后,存在永久不孕的风险。本文介绍了直肠癌患者的常规放射治疗技术,由于睾丸中剂量的减少,可以降低不育的风险。通讯:Edis Dedovic,乌尔图兹拉大学临床中心医学物理和辐射防护系。伊布雷博士Pašića,图兹拉75000,波斯尼亚和黑塞哥维那,电话:+38761675094;电子邮件:edis.djedovic@yahoo.com
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Colorectal cancer conventional radiotherapy treatment technique with sparing the testicles
Colorectal cancer was the third most common cancer in 2012, with higher percentage of incidence in less developed countries. In a less developed countries usually conventional radiotherapy technique is used for treatment of colorectal cancer. Using this technique testicles receive a dose from scattered radiation, due to the divergence of fields towards the testicles. We tried to re-duce a testicular dose avoiding the divergence of fields towards the testicles. For that aim 28 mail patients (mean age 51.8 years), treated with 45 Gy using the conventional 3 field technique were selected and subjected to retrospective dosimetric study using the avoiding divergence technique. Significant statistical difference was showed between the two proposed techniques (5.66 Gy, 3.53 Gy; p <0.0001) in favour of avoiding divergence technique (median of the min-imum doses to the testicles: 0.20 Gy, 0.09 Gy and the median of the maximum doses to the testicles: 15.32 Gy, 14.00 Gy). Patients with rectal cancer who are going to receive radiotherapy treatment with conventional radiotherapy tech-nique, are at risk of permanent infertility. This paper presents conventional ra-diotherapy technique, for the patients with rectal cancer which will, due to re-duction of medium testicular dose, reduce the risk of infertility. *Correspondence to: Edis Dedovic, Depertment of medical physics and radiation protection, University Clinical Centre Tuzla, Ul. prof. dr. Ibre Pašića, Tuzla 75000, Bosnia and Herzegovina, Tel: +38761675094; E-mail: edis.djedovic@yahoo.com
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信