Breathe最新文献_第8页

Treatment strategies for Mycobacterium avium pulmonary disease. 鸟分枝杆菌肺病的治疗策略。

IF 3.4

Breathe Pub Date : 2026-01-27 eCollection Date: 2026-01-01 DOI: 10.1183/20734735.0254-2025

Rannvá Winther, Søren Sperling, Andreas Fløe

引用次数: 0

Work-life balance as early career respiratory experts and ERS representatives: personal experiences, reflections and potential solutions for improvement. 作为早期职业呼吸专家和ERS代表的工作与生活平衡：个人经验、反思和潜在的改进解决方案。

IF 3.4

Breathe Pub Date : 2026-01-27 eCollection Date: 2026-01-01 DOI: 10.1183/20734735.0005-2025

Mathieu Marillier, Athénaïs Boucly, Matteo Siciliano, Marjolein A Heuvelmans, Amanda Dandanell Juul, Chiara Premuda, Susanne J H Vijverberg, Heleen Demeyer, Laura Fabbri, Augusta Beech, Thomas Gille, Sara Cuevas Ocaña

{"title":"Work-life balance as early career respiratory experts and ERS representatives: personal experiences, reflections and potential solutions for improvement.","authors":"Mathieu Marillier, Athénaïs Boucly, Matteo Siciliano, Marjolein A Heuvelmans, Amanda Dandanell Juul, Chiara Premuda, Susanne J H Vijverberg, Heleen Demeyer, Laura Fabbri, Augusta Beech, Thomas Gille, Sara Cuevas Ocaña","doi":"10.1183/20734735.0005-2025","DOIUrl":"https://doi.org/10.1183/20734735.0005-2025","url":null,"abstract":"Work-life balance is a real challenge for early career respiratory professionals striving to manage clinical responsibilities, research, teaching and professional commitments. In this collective reflection by members of the European Respiratory Society Early Career Member Committee, we openly explore our own experiences, struggles and lessons learned in the pursuit of balance. While some of us feel we have found a rhythm that works, many are still navigating fluctuating demands, blurred boundaries and long hours that spill into evenings, weekends and even holidays. Parenthood, changing roles and growing responsibilities have reshaped our priorities and tested our limits. Still, we remain deeply passionate about our work. Through honest discussion, we share personal strategies such as setting boundaries, using time-management tools and leaning on support networks, and highlight the emotional toll when the balance is lost. We also recognise that systemic change is needed: fairer compensation, cultural shifts around overwork, and structural support for young professionals. This article is both a reflection and a call to action: to take care of ourselves, to support one another and to shape a professional culture where wellbeing is valued as much as productivity. We hope our shared experiences resonate and offer encouragement to other early career respiratory professionals.","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"22 1","pages":"250005"},"PeriodicalIF":3.4,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12839467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146092101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-tuberculosis lung disease. 结核后肺病。

IF 3.4

Breathe Pub Date : 2026-01-27 eCollection Date: 2026-01-01 DOI: 10.1183/20734735.0243-2025

Yasmeen Al-Hindawi, Onno W Akkerman, Anthony Byrne, Raquel Duarte, Ernesto Jaramillo, Olha Konstantynovska, Chiara Premuda, Cristina Vilaplana, Giovanni Battista Migliori, Gunar Günther, Kerri Viney, Dennis Falzon

{"title":"Post-tuberculosis lung disease.","authors":"Yasmeen Al-Hindawi, Onno W Akkerman, Anthony Byrne, Raquel Duarte, Ernesto Jaramillo, Olha Konstantynovska, Chiara Premuda, Cristina Vilaplana, Giovanni Battista Migliori, Gunar Günther, Kerri Viney, Dennis Falzon","doi":"10.1183/20734735.0243-2025","DOIUrl":"https://doi.org/10.1183/20734735.0243-2025","url":null,"abstract":"Tuberculosis (TB) burden concentrates in low-income settings and remains the leading global cause of death from a single infectious agent, despite that it is preventable and treatable. TB-associated lung diseases (TBALD), a broad range of respiratory abnormalities which can start before or during a TB episode, may increase morbidity. TBALD may persist after successful completion of TB treatment as post-TB lung disease (PTLD). PTLD varies in severity and is characterised by persistent respiratory symptoms and lung impairment that can significantly impact social activities, health-related quality of life, and long-term survival. Risk factors for PTLD include increasing age, smoking, HIV infection, delayed diagnosis, and poor socioeconomic conditions. Action to limit PTLD may be taken before TB develops through TB screening, early diagnosis and TB preventive treatment, during treatment of TB, and upon its completion. Early detection, clinical assessment, and tailored management (including smoking cessation, immunisation, addressing respiratory comorbidities, pulmonary rehabilitation and social protection) can mitigate impairment and disability. Healthcare providers and national programmes play a vital role through clinical follow-up, patient education, and integration of TBALD care into broader health and social protection services. Sustained funding and research are crucial for this and to develop new tools to enhance care.","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"22 1","pages":"250243"},"PeriodicalIF":3.4,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12839470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146092042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nonpharmacological interventions for managing infections in chronic respiratory diseases: a comprehensive overview. 管理慢性呼吸道疾病感染的非药物干预：全面概述。

IF 3.4

Breathe Pub Date : 2026-01-27 eCollection Date: 2026-01-01 DOI: 10.1183/20734735.0058-2025

Chiara Premuda, Martina Santambrogio, Sofia Misuraca, Gianmarco Putti, Filippo Maraz, Andrea Sarassi, Anna Bulfamante, Francesco Blasi, Andrea Gramegna

引用次数: 0

Secondary infections following tuberculosis: epidemiology, pathogenesis and clinical implications. 结核病继发感染：流行病学、发病机制和临床意义。

IF 3.4

Breathe Pub Date : 2026-01-27 eCollection Date: 2026-01-01 DOI: 10.1183/20734735.0055-2025

Mariona Cortacans, Nino Gogichadze, Pablo Soldevilla, Zoran Stojanovic, Onno Akkerman, Raquel Duarte, Cristina Vilaplana

{"title":"Secondary infections following tuberculosis: epidemiology, pathogenesis and clinical implications.","authors":"Mariona Cortacans, Nino Gogichadze, Pablo Soldevilla, Zoran Stojanovic, Onno Akkerman, Raquel Duarte, Cristina Vilaplana","doi":"10.1183/20734735.0055-2025","DOIUrl":"https://doi.org/10.1183/20734735.0055-2025","url":null,"abstract":"This review brings together global data on bacterial, fungal, nontuberculous mycobacterial (NTM) and viral infections that complicate the course of individuals following the diagnosis of pulmonary or extrapulmonary tuberculosis (TB). It shows how residual structural lung damage (bronchiectasis, cavitation, residual fibrotic lesions) and persistent immune dysregulation create niches for pathogens, most notably Pseudomonas aeruginosa, Aspergillus spp., Mycobacterium avium complex and herpes zoster virus. Although bacterial infections in post-TB bronchiectasis are the most consistently documented, chronic pulmonary aspergillosis and NTM disease add substantial morbidity. Viral complications beyond herpes zoster and influenza remain poorly characterised, underscoring a critical evidence gap. In extrapulmonary TB survivors, organ-specific sequelae pose additional infection risks that are rarely quantified. Across all categories, inconsistent case definitions, under-utilisation of the 10th revision of the International Classification of Diseases coding, and lack of prospective cohorts have obscured the true burden of post-TB infections. The review concludes by calling for standardised diagnostic criteria, enhanced epidemiological tracking, and integrated post-treatment care pathways including preventive vaccinations to mitigate long-term health consequences in this vulnerable population.","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"22 1","pages":"250055"},"PeriodicalIF":3.4,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12839463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146092068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

When tuberculosis turns critical: a rare constellation of severe complications. 结核病危重时：罕见的严重并发症。

IF 3.4

Breathe Pub Date : 2026-01-27 eCollection Date: 2026-01-01 DOI: 10.1183/20734735.0228-2025

Zainab Afzal, David Quigley, John Hogan, Fiona Murphy, Reza Ghasemi

引用次数: 0

A 26-year-old with persistent cough of unclear origin. 26岁，持续咳嗽，原因不明。

IF 3.4

Breathe Pub Date : 2025-12-16 eCollection Date: 2025-10-01 DOI: 10.1183/20734735.0273-2025

Tiantian Zhang, Yidan Sun, Guochao Shi, Xiaoyan Chen

引用次数: 0

Tuberculosis-associated immune reconstitution inflammatory syndrome in a non-immunocompromised patient. 非免疫功能低下患者结核相关免疫重建炎症综合征

IF 3.4

Breathe Pub Date : 2025-12-16 eCollection Date: 2025-10-01 DOI: 10.1183/20734735.0255-2025

Vasileios Angelopoulos, Anastasia Papanikolaou, Christos Chronis, Christos Kyriakopoulos, Angelos Ladias, Antonia Assioura, Athena Gogali, Konstantinos Kostikas, Evgenia Salla

引用次数: 0

Ethical, gamified spirometry for preschoolers: a step-by-step protocol for reliable lung-function data. 伦理的，游戏化的学龄前儿童肺活量测定法：可靠的肺功能数据的一步一步的协议。

IF 3.4

Breathe Pub Date : 2025-12-16 eCollection Date: 2025-10-01 DOI: 10.1183/20734735.0266-2025

Radu Marian Gheorghiu, Alexandra Tița

引用次数: 0

Exploring pleural effusion characterisation with quantitative thoracic ultrasound imaging: a viewpoint on the investigational role of pixel-based echogenicity analysis in transudate and exudate differentiation. 定量胸部超声成像探讨胸腔积液的特征：基于像素的回声分析在渗出液鉴别中的研究作用。

IF 3.4

Breathe Pub Date : 2025-12-16 eCollection Date: 2025-10-01 DOI: 10.1183/20734735.0282-2025

Guido Marchi

{"title":"Exploring pleural effusion characterisation with quantitative thoracic ultrasound imaging: a viewpoint on the investigational role of pixel-based echogenicity analysis in transudate and exudate differentiation.","authors":"Guido Marchi","doi":"10.1183/20734735.0282-2025","DOIUrl":"10.1183/20734735.0282-2025","url":null,"abstract":"Pleural effusion represents a frequent and diagnostically challenging condition across multiple clinical settings. Conventional characterisation relies on invasive thoracentesis and biochemical analysis, with Light's criteria offering high sensitivity but limited specificity. Procedural risks and patient factors may limit fluid sampling, highlighting the need for complementary, noninvasive approaches. Recent advances in thoracic ultrasound (TUS) suggest that quantitative assessment of pleural fluid (PF) echogenicity, particularly pixel density analysis and hypoechogenicity index, may represent an investigational approach for objective and reproducible evaluation. Preliminary studies using standardised image analysis platforms, such as ImageJ, indicate that exudative effusions more frequently exhibit higher pixel density than transudates, in association with markers of cellularity, protein content, and inflammation. Hybrid scoring systems combining quantitative metrics with morphological sonographic features, such as septations, fibrin strands, and debris, have been explored and may enhance diagnostic specificity, although validation remains limited. However, methodological constraints, operator- and device-dependent variability and small sample sizes continue to restrict their applicability in routine clinical practice. Emerging approaches, including artificial intelligence, may be able to mitigate these limitations by standardising measurements, harmonising grayscale output, and integrating clinical, laboratory and imaging data to generate real-time risk scores. In the absence of robustly validated evidence, quantitative TUS should be regarded as an investigational adjunct, with potential to refine PF characterisation, support clinical decision-making, and inform future research on noninvasive diagnostic strategies.","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 4","pages":"250282"},"PeriodicalIF":3.4,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12706588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145773681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0