Breathe最新文献_第10页

The impact of poor housing and indoor air quality on respiratory health in children. 不良住房和室内空气质量对儿童呼吸系统健康的影响。

IF 2

Breathe Pub Date : 2023-06-01 DOI: 10.1183/20734735.0058-2023

Karl A Holden, Alice R Lee, Daniel B Hawcutt, Ian P Sinha

{"title":"The impact of poor housing and indoor air quality on respiratory health in children.","authors":"Karl A Holden, Alice R Lee, Daniel B Hawcutt, Ian P Sinha","doi":"10.1183/20734735.0058-2023","DOIUrl":"https://doi.org/10.1183/20734735.0058-2023","url":null,"abstract":"It is becoming increasingly apparent that poor housing quality affects indoor air quality, significantly impacting on respiratory health in children and young people. Exposure to damp and/or mould in the home, cold homes and the presence of pests and pollutants all have a significant detrimental impact on child respiratory health. There is a complex relationship between features of poor-quality housing, such as being in a state of disrepair, poor ventilation, overcrowding and being cold, that favour an environment resulting in poor indoor air quality. Children living in rented (private or public) housing are more likely to come from lower-income backgrounds and are most at risk of living in substandard housing posing a serious threat to respiratory health. Children have the right to safe and adequate housing, and research has shown that either rehousing or making modifications to poor-quality housing to improve indoor air quality results in improved respiratory health. Urgent action is needed to address this threat to health. All stakeholders should understand the relationship between poor-quality housing and respiratory health in children and act, working with families, to redress this modifiable risk factor.Educational aims: The reader should understand how housing quality and indoor air quality affect respiratory health in children.The reader should understand which children are at most risk of living in poor-quality housing.The reader should understand what policy recommendations have been made and what actions need to be undertaken to improve housing quality and respiratory health in children and young people.","PeriodicalId":9292,"journal":{"name":"Breathe","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/58/b8/EDU-0058-2023.PMC10461733.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10122601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The exposome in respiratory diseases: multiple preventable risk factors from early life to adulthood. 呼吸系统疾病的暴露:从生命早期到成年的多种可预防的危险因素。

IF 2

Breathe Pub Date : 2023-06-01 DOI: 10.1183/20734735.0034-2023

Marine Savouré, Katie Eminson, Lucile Sese, Orianne Dumas, Yutong Samuel Cai

{"title":"The exposome in respiratory diseases: multiple preventable risk factors from early life to adulthood.","authors":"Marine Savouré, Katie Eminson, Lucile Sese, Orianne Dumas, Yutong Samuel Cai","doi":"10.1183/20734735.0034-2023","DOIUrl":"https://doi.org/10.1183/20734735.0034-2023","url":null,"abstract":"The increasing global burden of respiratory diseases over the last decades raises questions about the impact of environmental factors during industrialisation and urbanisation. Although the knowledge of environmental epidemiology is growing, it is still unclear what the most critical exposure windows are for respiratory health. In addition, the relationships between different environmental exposures can be complex. The exposome approach investigating all non-genetic factors on health has been developed in recent years but has been little applied in respiratory health to date. This journal club article reviews three recent publications investigating the effects of environmental exposures, considered separately or in an exposome approach with different exposure windows, on respiratory health outcomes. These three studies highlight targets for action in primary and secondary prevention. Two studies, using data from the INMA and RHINESSA cohorts, support the regulation and reduction of phthalates and air pollution, respectively. Moreover, the exposome approach conducted in the NutriNet-Santé cohort emphasises that risk reduction must involve a multi-interventional approach targeting both specific early-life risk factors and promotion of a healthy lifestyle in adulthood. These three articles also present research perspectives in environmental epidemiology.","PeriodicalId":9292,"journal":{"name":"Breathe","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d5/d1/EDU-0034-2023.PMC10292782.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9727124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Experience of being chair and co-chair of the ECMC and reasons why you should be the NEXT. 担任ECMC主席和联合主席的经历，以及为什么你应该成为NEXT的原因。

IF 2

Breathe Pub Date : 2023-06-01 DOI: 10.1183/20734735.0089-2023

James Parkin, Justine Devulder, Susanne J H Vijverberg, Niki Ubags, Maxime Patout, Sara Cuevas Ocaña, Thomas Gille, Joana Cruz

引用次数: 3

Current and future developments in the pharmacology of asthma and COPD: ERS seminar, Naples 2022. 哮喘和慢性阻塞性肺病药理学的当前和未来发展:ERS研讨会，那不勒斯2022。

IF 2

Breathe Pub Date : 2023-06-01 DOI: 10.1183/20734735.0267-2022

Daiana Stolz, Maria Gabriella Matera, Paola Rogliani, Maarten van den Berge, Eleni Papakonstantinou, Reinoud Gosens, Dave Singh, Nicola Hanania, Mario Cazzola, Anke-Hilse Maitland-van der Zee, Laura Fregonese, Alexander G Mathioudakis, Jørgen Vestbo, Maia Rukhadze, Clive P Page

{"title":"Current and future developments in the pharmacology of asthma and COPD: ERS seminar, Naples 2022.","authors":"Daiana Stolz, Maria Gabriella Matera, Paola Rogliani, Maarten van den Berge, Eleni Papakonstantinou, Reinoud Gosens, Dave Singh, Nicola Hanania, Mario Cazzola, Anke-Hilse Maitland-van der Zee, Laura Fregonese, Alexander G Mathioudakis, Jørgen Vestbo, Maia Rukhadze, Clive P Page","doi":"10.1183/20734735.0267-2022","DOIUrl":"https://doi.org/10.1183/20734735.0267-2022","url":null,"abstract":"Pharmacological management of airway obstructive diseases is a fast-evolving field. Several advances in unravelling disease mechanisms as well as intracellular and molecular pathways of drug action have been accomplished. While the clinical translation and implementation of in vitro results to the bedside remains challenging, advances in comprehending the mechanisms of respiratory medication are expected to assist clinicians and scientists in identifying meaningful read-outs and designing clinical studies. This European Respiratory Society Research Seminar, held in Naples, Italy, 5-6 May 2022, focused on current and future developments of the drugs used to treat asthma and COPD; on mechanisms of drug action, steroid resistance, comorbidities and drug interactions; on prognostic and therapeutic biomarkers; on developing novel drug targets based on tissue remodelling and regeneration; and on pharmacogenomics and emerging biosimilars. Related European Medicines Agency regulations are also discussed, as well as the seminar's position on the above aspects.","PeriodicalId":9292,"journal":{"name":"Breathe","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/ae/EDU-0267-2022.PMC10292790.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9729776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rolling out new anti-tuberculosis drugs without diagnostic capacity. 在没有诊断能力的情况下推出新的抗结核药物。

IF 2.3

Breathe Pub Date : 2023-06-01 Epub Date: 2023-07-11 DOI: 10.1183/20734735.0084-2023

Tara Ness, Le Hong Van, Ilze Petermane, Raquel Duarte, Christoph Lange, Dick Menzies, Daniela Maria Cirillo

引用次数: 0

Air quality and respiratory health in children. 儿童的空气质量和呼吸系统健康。

IF 2

Breathe Pub Date : 2023-06-01 DOI: 10.1183/20734735.0040-2023

Sathya Swarup Aithal, Ishaan Sachdeva, Om P Kurmi

引用次数: 2

Routine FEV₁ measurement is essential in diagnosis and monitoring of childhood asthma: myth or maxim? 常规FEV1测量对儿童哮喘的诊断和监测至关重要：神话还是格言？

IF 2

Breathe Pub Date : 2023-06-01 Epub Date: 2023-08-15 DOI: 10.1183/20734735.0048-2023

Maria Octavia Onisor, Steve Turner

{"title":"Routine FEV1 measurement is essential in diagnosis and monitoring of childhood asthma: myth or maxim?","authors":"Maria Octavia Onisor, Steve Turner","doi":"10.1183/20734735.0048-2023","DOIUrl":"10.1183/20734735.0048-2023","url":null,"abstract":"Childhood asthma is a common condition in children. This review describes the evidence from seven asthma guidelines for using spirometry in the diagnosis and monitoring of childhood asthma. All guidelines recommend spirometry as the primary test to be performed for diagnosing asthma in children aged >5 years. Spirometry is often normal in children with asthma. Guidelines are not consistent with respect to whether forced expiratory volume in 1 s (FEV1) or FEV1/forced vital capacity (FVC) should be measured, or their threshold for \"abnormal\" spirometry, and we describe the sensitivity and specificity for these different cut-offs. The role of spirometry in monitoring asthma is less clear in the guidelines, and some do not suggest spirometry should be done. There is no consensus on what spirometric measurement should be used, how often it should be measured and what is a minimum clinically important change in spirometry. The role of spirometry in diagnosing asthma is more clearly established when compared to its role in monitoring asthma. The potential of spirometry to aid decision making for asthma diagnosis and monitoring in children remains to be fully evaluated.Educational aims: To provide knowledge of the commonly used guidelines for asthma diagnosis and management.To give insight into the opportunities and challenges in using spirometry to diagnose and monitor asthma in children.To provide an understanding of the precision of spirometry for diagnosing asthma.","PeriodicalId":9292,"journal":{"name":"Breathe","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/24/de/EDU-0048-2023.PMC10461742.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10648460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The exposome concept: how has it changed our understanding of environmental causes of chronic respiratory diseases? 暴露概念:它如何改变了我们对慢性呼吸道疾病的环境原因的理解?

IF 2

Breathe Pub Date : 2023-06-01 DOI: 10.1183/20734735.0044-2023

Alicia Guillien, Manosij Ghosh, Thomas Gille, Orianne Dumas

引用次数: 1

Greenness exposure: beneficial but multidimensional. 绿色暴露:有益但多维的。

IF 2

Breathe Pub Date : 2023-06-01 DOI: 10.1183/20734735.0221-2022

Ane Johannessen, Shanshan Xu, Achenyo Peace Abbah, Christer Janson

{"title":"Greenness exposure: beneficial but multidimensional.","authors":"Ane Johannessen, Shanshan Xu, Achenyo Peace Abbah, Christer Janson","doi":"10.1183/20734735.0221-2022","DOIUrl":"https://doi.org/10.1183/20734735.0221-2022","url":null,"abstract":"Many studies have shown that greenness has beneficial health effects, particularly on psychological and cardiovascular outcomes. In this narrative review, we provide a synthesis of knowledge regarding greenness exposure and respiratory health. The following outcomes were reviewed: respiratory mortality, lung cancer mortality, lung cancer incidence, respiratory hospitalisations, lung function, COPD, and asthma. We identified 174 articles through a literature search in PubMed, of which 42 were eligible for inclusion in this review. The most common marker for greenness exposure was the normalised difference vegetation index (NDVI), which was used in 29 out of 42 papers. Other markers used were tree canopy cover, landcover/land-use, plant diversity, density of tall trees and subjectively perceived greenness. We found beneficial effects of greenness in most studies regarding respiratory mortality, lung cancer incidence, respiratory hospitalisations and lung function. For lung cancer mortality, asthma and COPD, the effects of greenness were less clear cut. While many aspects of greenness are beneficial, some aspects may be harmful, and greenness may have different health effects in different population subgroups. Future studies of greenness and respiratory diseases should focus on asthma and COPD, on effects in different population subgroups and on disentangling the health effects of the various greenness dimensions.","PeriodicalId":9292,"journal":{"name":"Breathe","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7d/34/EDU-0221-2022.PMC10461730.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10475377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Does one size fit all? An update on chronic ventilatory support in different respiratory illnesses. 一个尺码适合所有人吗?不同呼吸系统疾病的慢性呼吸支持的最新进展。

IF 2

Breathe Pub Date : 2023-06-01 DOI: 10.1183/20734735.0046-2023

Annalisa Carlucci, Maxime Patout, João Carlos Winck

{"title":"Does one size fit all? An update on chronic ventilatory support in different respiratory illnesses.","authors":"Annalisa Carlucci, Maxime Patout, João Carlos Winck","doi":"10.1183/20734735.0046-2023","DOIUrl":"https://doi.org/10.1183/20734735.0046-2023","url":null,"abstract":"Home noninvasive ventilation (HNIV) improves outcomes in different disease categories. In this article, we discuss indications for when and how to initiate HNIV in COPD, obesity hypoventilation syndrome (OHS) and neuromuscular disorders (NMD). While in COPD, significant diurnal hypercapnia and high-intensity HNIV are essential ingredients for success, in NMD and OHS, early respiratory changes are best detected during sleep through oxy-capnography associated (or not) with respiratory polygraphy. In COPD and OHS, it is crucial to consider the coexistence of obstructive sleep apnoea because treatment with continuous positive airway pressure may be the simplest and most effective treatment that should be proposed even in hypercapnic patients as first-line therapy. In NMD, the need for continuous HNIV and eventual switching to tracheostomy ventilation makes this group's management more challenging. Achieving successful HNIV by improving quality of sleep, quality of life and keeping a good adherence to the therapy is a challenge, above all in COPD patients. In OHS patients, on top of HNIV, initiation of other interventions such as weight loss management is crucial. More resources should be invested in improving all these aspects. Telemonitoring represents a promising method to improve titration and follow-up of HNIV.","PeriodicalId":9292,"journal":{"name":"Breathe","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8c/24/EDU-0046-2023.PMC10365079.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9875975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1