Brain Circulation最新文献

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Basilar artery recanalization by proximal balloon occlusion and aspiration in a single vessel vertebrobasilar system: A case report. 单血管椎基底动脉系统近端球囊闭塞与抽吸再通1例。
IF 1.9 4区 医学
Brain Circulation Pub Date : 2023-04-01 DOI: 10.4103/bc.bc_79_22
Matthew Gusler, Seyed-Mostafa Razavi, Aaron Grossman, Charles Prestigiacomo, Ashkan Mowla, Peyman Shirani
{"title":"Basilar artery recanalization by proximal balloon occlusion and aspiration in a single vessel vertebrobasilar system: A case report.","authors":"Matthew Gusler,&nbsp;Seyed-Mostafa Razavi,&nbsp;Aaron Grossman,&nbsp;Charles Prestigiacomo,&nbsp;Ashkan Mowla,&nbsp;Peyman Shirani","doi":"10.4103/bc.bc_79_22","DOIUrl":"https://doi.org/10.4103/bc.bc_79_22","url":null,"abstract":"<p><p>The authors present a case of a patient with a hypoplastic right vertebral artery (VA) ending in the posterior inferior cerebellar artery who sustained an acute onset basilar artery occlusion. A balloon-guided catheter was used to proximally occlude the dominant left VA, and aspiration was applied until reversal of flow was achieved in the basilar artery. Thus, basilar artery reperfusion was achieved without the need for stent-retrieval thrombectomy. We believe this represents the first described case of successful thrombectomy in the vertebrobasilar system using only proximal artery occlusion and aspiration. This novel technique may decrease the time to recanalization and improve outcomes for patients with acute basilar artery occlusion in the setting of a hypoplastic contralateral VA.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"9 2","pages":"103-106"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/91/20/BC-9-103.PMC10419728.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9996321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transradial access for neurointerventional procedures: A practical approach. 神经介入手术的经桡骨通路:一种实用的方法。
IF 1.9 4区 医学
Brain Circulation Pub Date : 2023-04-01 DOI: 10.4103/bc.bc_101_22
Mohammad Hossein Mirbolouk, Feizollah Ebrahimnia, Reza Gorji, Payam Sasannejad, Samira Zabihyan, Mohammad Adeeb Hoveizavi, Yousefali Garivani, Zahra Mirzaasgari, Saeed Abdollahifard, Ashkan Mowla, Humain Baharvahdat
{"title":"Transradial access for neurointerventional procedures: A practical approach.","authors":"Mohammad Hossein Mirbolouk,&nbsp;Feizollah Ebrahimnia,&nbsp;Reza Gorji,&nbsp;Payam Sasannejad,&nbsp;Samira Zabihyan,&nbsp;Mohammad Adeeb Hoveizavi,&nbsp;Yousefali Garivani,&nbsp;Zahra Mirzaasgari,&nbsp;Saeed Abdollahifard,&nbsp;Ashkan Mowla,&nbsp;Humain Baharvahdat","doi":"10.4103/bc.bc_101_22","DOIUrl":"https://doi.org/10.4103/bc.bc_101_22","url":null,"abstract":"<p><strong>Introduction: </strong>Transradial approach (TRA) is a new technique proposed for performing cerebral angiography and neuro-interventional procedures. In this article, we sought to provide a step-by-step guide for carrying out a diagnostic cerebral angiography using this approach and summarize our center's experience.</p><p><strong>Material and methods: </strong>Records of patients since January 2020 were investigated, and data on demographic indices, reports of the procedures, outcomes, and complications were extracted. Then, these data were used to develop a step-by-step instruction for TRA cerebral angiography.</p><p><strong>Results: </strong>Two hundred eighty-nine patients matched our eligibility criteria with a mean age of 50 years and a female-to-male ratio of 1.18. Overall, TRA was carried out successfully for 97.2% (281 patients). In case TRA failed, transfemoral approach was considered for the procedure. Three minor complications (two vasospasm and one small hematoma) and two major complications (one pseudoaneurysm of the radial artery and one radial artery avulsion) were observed.</p><p><strong>Conclusion: </strong>This article covers challenges a neurointerventionalist may face during a diagnostic cerebral angiography using TRA. Furthermore, our findings indicated that cerebral angiography with TRA might be performed safely and with a great success rate.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"9 2","pages":"88-93"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/81/2a/BC-9-88.PMC10419729.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9996326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An ischemic myelopathy case series: Flaccid paraplegia following a spike ball save and numbness while walking normally. 缺血性脊髓病病例系列:刺球后的弛缓性截瘫和正常行走时的麻木。
IF 1.9 4区 医学
Brain Circulation Pub Date : 2023-04-01 DOI: 10.4103/bc.bc_80_22
Caroline A Heckman, Derryl J Miller, Kelly M Kremer, Mesha L Martinez, Andrew H Jea
{"title":"An ischemic myelopathy case series: Flaccid paraplegia following a spike ball save and numbness while walking normally.","authors":"Caroline A Heckman,&nbsp;Derryl J Miller,&nbsp;Kelly M Kremer,&nbsp;Mesha L Martinez,&nbsp;Andrew H Jea","doi":"10.4103/bc.bc_80_22","DOIUrl":"https://doi.org/10.4103/bc.bc_80_22","url":null,"abstract":"<p><p>Spinal cord infarctions in children are rare and early magnetic resonance imaging studies are often negative. A high clinical suspicion must be maintained to identify stroke and initiate workup for underlying etiology to suggest appropriate treatment. We present two cases of spinal cord infarction without major preceding trauma. The first was caused by disc herniation and external impingement of a radiculomedullary artery and the second was due to fibrocartilaginous embolism with classic imaging findings of ventral and dorsal cord infarctions, respectively. These cases were treated conservatively with diagnostic workup and aspirin, though additional treatments which can be considered with prompt diagnosis are also explored in our discussion. Both cases recovered the ability to ambulate independently within months. Case 1 is attending college and ambulates campus with a single-point cane. Case 2 ambulates independently, though has some difficulty with proprioception of the feet so uses wheelchairs for long-distance ambulation.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"9 2","pages":"107-111"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a6/93/BC-9-107.PMC10419739.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9996327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modifying skin flaps for achieving very large decompressive craniectomies in malignant middle cerebral artery territory infarcts: A technical note. 改良皮瓣用于恶性大脑中动脉区域梗死的大面积减压颅骨切除术:技术说明。
IF 1.9 4区 医学
Brain Circulation Pub Date : 2023-04-01 DOI: 10.4103/bc.bc_98_22
Shamshuddin Patel, Rajesh Bhosle, Nabanita Ghosh, Sayan Das, Prasad Krishnan
{"title":"Modifying skin flaps for achieving very large decompressive craniectomies in malignant middle cerebral artery territory infarcts: A technical note.","authors":"Shamshuddin Patel,&nbsp;Rajesh Bhosle,&nbsp;Nabanita Ghosh,&nbsp;Sayan Das,&nbsp;Prasad Krishnan","doi":"10.4103/bc.bc_98_22","DOIUrl":"https://doi.org/10.4103/bc.bc_98_22","url":null,"abstract":"<p><strong>Introduction: </strong>Decompressive craniectomy is a well described treatment to salvage life in large middle cerebral artery (MCA) territory infarcts. The size of the craniectomy is limited by the size of the skin incision and very large craniectomies need large skin flaps that are prone to necrosis at the wound margins.</p><p><strong>Material and methods: </strong>We describe two modifications in the skin flap that we have used in 7 patients to achieve very large bony decompressions in malignant MCA infarctions without compromising on flap vascularity. One consists of a linear extension posteriorly from the question mark or reverse question mark incision while the other is an \"n\" shaped incision.</p><p><strong>Results: </strong>With these modifications we achieved craniectomies of size 15.6-17.8 cm in the anteroposterior and 10.7-12 cm in vertical axis of the bone flap removed in our patients. There were no additional procedural or wound related complications in a 6-month follow up.</p><p><strong>Conclusions: </strong>Removal of a standard size bone flap may achieve suboptimal decompression in cases of large MCA territory infarctions. Imaginative tailoring of skin flaps helps to remove larger volumes of skull with no added procedural morbidity.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"9 2","pages":"116-120"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/01/a3/BC-9-116.PMC10419731.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10001558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intravenous thrombolysis for acute ischemic stroke: From alteplase to tenecteplase. 静脉溶栓治疗急性缺血性卒中:从阿替普酶到替尼替普酶。
IF 1.9 4区 医学
Brain Circulation Pub Date : 2023-04-01 DOI: 10.4103/bc.bc_70_22
Nan Yang, Hangil Lee, Chuanjie Wu
{"title":"Intravenous thrombolysis for acute ischemic stroke: From alteplase to tenecteplase.","authors":"Nan Yang,&nbsp;Hangil Lee,&nbsp;Chuanjie Wu","doi":"10.4103/bc.bc_70_22","DOIUrl":"https://doi.org/10.4103/bc.bc_70_22","url":null,"abstract":"Stroke is one of the primary causes of morbidity and death worldwide. While intravenous (IV) thrombolysis with alteplase has been widely proven to be beneficial for acute ischemic stroke patients, it still has many limitations. Tenecteplase, a revised version of alteplase, is a potential alternative IV thrombolytic agent that has benefits over alteplase. The aim of this mini-review is to summarize the advancements in IV thrombolysis for severe ischemic stroke, specifically the development and transition from alteplase to tenecteplase.","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"9 2","pages":"61-63"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/22/62/BC-9-61.PMC10419734.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9996324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatic responses following acute ischemic stroke: A clinical research update. 急性缺血性脑卒中后肝脏反应:最新临床研究。
IF 1.9 4区 医学
Brain Circulation Pub Date : 2023-04-01 DOI: 10.4103/bc.bc_31_23
Honglian Duan, Xiaokun Geng, Yuchuan Ding
{"title":"Hepatic responses following acute ischemic stroke: A clinical research update.","authors":"Honglian Duan,&nbsp;Xiaokun Geng,&nbsp;Yuchuan Ding","doi":"10.4103/bc.bc_31_23","DOIUrl":"https://doi.org/10.4103/bc.bc_31_23","url":null,"abstract":"<p><p>Acute ischemic stroke (AIS) not only affects the brain but also has significant implications for peripheral organs through neuroendocrine regulation. This reciprocal relationship influences overall brain function and stroke prognosis. Recent research has highlighted the importance of poststroke liver changes in determining patient outcomes. In our previous study, we investigated the relationship between stroke and liver function. Our findings revealed that the prognostic impact of stress-induced hyperglycemia in patients undergoing acute endovascular treatment for acute large vessel occlusion is closely related to their preexisting diabetes status. We found that the liver contributes to stress hyperglycemia after AIS by increasing hepatic gluconeogenesis and decreasing hepatic insulin sensitivity. These changes are detrimental to the brain, particularly in patients without diabetes. Furthermore, we examined the role of bilirubin, a byproduct of hepatic hemoglobin metabolism, in stroke pathophysiology. Our results demonstrated that blood bilirubin levels can serve as predictors of stroke severity and may hold therapeutic potential for reducing oxidative stress-induced stroke injury in patients with mild stroke. These results underscore the potential role of the liver in the oxidative stress response following AIS, paving the way for further investigation into liver-targeted therapeutic strategies to improve stroke prognosis and patient outcomes.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"9 2","pages":"57-60"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/65/65/BC-9-57.PMC10419733.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9989969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neutrophil-to-leukocyte ratio and admission glycemia as predictors of short-term death in very old elderlies with lobar intracerebral hemorrhage. 中性粒细胞与白细胞比率和入院血糖作为高龄老年人大叶性脑出血短期死亡的预测因子
IF 1.9 4区 医学
Brain Circulation Pub Date : 2023-04-01 DOI: 10.4103/bc.bc_5_23
Marta Pereira, Rafael Batista, Ana Marreiros, Hipolito Nzwalo
{"title":"Neutrophil-to-leukocyte ratio and admission glycemia as predictors of short-term death in very old elderlies with lobar intracerebral hemorrhage.","authors":"Marta Pereira,&nbsp;Rafael Batista,&nbsp;Ana Marreiros,&nbsp;Hipolito Nzwalo","doi":"10.4103/bc.bc_5_23","DOIUrl":"https://doi.org/10.4103/bc.bc_5_23","url":null,"abstract":"<p><strong>Background: </strong>The incidence of spontaneous intracerebral hemorrhage (SICH) is highest in very old elderlies (≥75 years). The increasing use of antithrombotic drugs is shifting the epidemiology of SICH towards predominance of lobar subtype, suggesting an incremented propensity of bleeding associated with underlying cerebral amyloid angiopathy. With population aging and antithrombotic use, a parallel raise of proportion of lobar SICH is occurring. Improvement of prognostication in this specific age group and SICH type is needed. Routine blood biomarkers can contribute to prediction of short-term mortality after SICH.</p><p><strong>Objective: </strong>Our aim was to investigate the contribution of routine blood biomarkers for short-term mortality (30-days) in elderly patients with lobar SICH.</p><p><strong>Methods: </strong>Retrospective analysis of consecutive 130 patients with ≥ 75 years and lobar SICH. The outcome was 30-day mortality. Logistic regression analysis was used to investigate whether admission routine biomarkers can be used as predictors.</p><p><strong>Results: </strong>The case fatality was 40.8%. Admission glycaemia level, neutrophil to lymphocyte ratio and mean platelet volume were significantly different between groups (p = 0.001, p = 0.024, p = 0.038, respectively). There was no significant difference in all other routine biomarkers. On multivariate analysis, admission higher mean BG level (odds ratio [OR]: 1.010, 95% confidence interval [CI]: 1.001-1.019, p = 0.026) and neutrophil to lymphocyte ratio (OR: 1.070, 95% CI: 1.008-1.136, p = 0.027) emerged as predictors.</p><p><strong>Conclusion: </strong>In very old patients with lobar SICH, higher BG level and neutrophil to lymphocyte ratio are associated with increased risk of short-term death.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"9 2","pages":"94-98"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f1/79/BC-9-94.PMC10419730.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9989970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Computed tomography perfusion stroke mimics on RAPID commercial software: A case-based review. 基于RAPID商业软件的计算机断层扫描灌注脑卒中模拟:一项基于病例的回顾。
IF 1.9 4区 医学
Brain Circulation Pub Date : 2023-04-01 DOI: 10.4103/bc.bc_100_22
Amara Ahmed, Omar Hamam, Sanaz Ghaderi Niri, Georg Oeltzchner, Tushar Garg, Omar Elmandouh, Jarunee Intrapiromkul, Vivek Yedavalli
{"title":"Computed tomography perfusion stroke mimics on RAPID commercial software: A case-based review.","authors":"Amara Ahmed,&nbsp;Omar Hamam,&nbsp;Sanaz Ghaderi Niri,&nbsp;Georg Oeltzchner,&nbsp;Tushar Garg,&nbsp;Omar Elmandouh,&nbsp;Jarunee Intrapiromkul,&nbsp;Vivek Yedavalli","doi":"10.4103/bc.bc_100_22","DOIUrl":"https://doi.org/10.4103/bc.bc_100_22","url":null,"abstract":"<p><p>Acute ischemic stroke (AIS) is a leading cause of morbidity worldwide and can present with nonspecific symptoms, making diagnosis difficult. Many neurologic diseases present similarly to stroke; stroke mimics account for up to half of all hospital admissions for stroke. Stroke therapies carry risk, so accurate diagnosis of AIS is crucial for prompt treatment and prevention of adverse outcomes for patients with stroke mimics. Computed tomography (CT) perfusion techniques have been used to distinguish between nonviable tissue and penumbra. RAPID is an operator-independent, automated CT perfusion imaging software that can aid clinicians in diagnosing strokes quickly and accurately. In this case-based review, we demonstrate the applications of RAPID in differentiating between strokes and stroke mimics.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"9 2","pages":"68-76"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8f/22/BC-9-68.PMC10419735.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9996328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immune and inflammatory mechanism of remote ischemic conditioning: A narrative review. 远端缺血条件反射的免疫和炎症机制:综述。
IF 1.9 4区 医学
Brain Circulation Pub Date : 2023-04-01 DOI: 10.4103/bc.bc_57_22
Yi Xu, Yuan Wang, Xunming Ji
{"title":"Immune and inflammatory mechanism of remote ischemic conditioning: A narrative review.","authors":"Yi Xu,&nbsp;Yuan Wang,&nbsp;Xunming Ji","doi":"10.4103/bc.bc_57_22","DOIUrl":"https://doi.org/10.4103/bc.bc_57_22","url":null,"abstract":"<p><p>The benefits of remote ischemic conditioning (RIC) on multiple organs have been extensively investigated. According to existing research, suppressing the immune inflammatory response is an essential mechanism of RIC. Based on the extensive effects of RIC on cardiovascular and cerebrovascular diseases, this article reviews the immune and inflammatory mechanisms of RIC and summarizes the effects of RIC on immunity and inflammation from three perspectives: (1) the mechanisms of the impact of RIC on inflammation and immunity; (2) evidence of the effects of RIC on immune and inflammatory processes in ischaemic stroke; and (3) possible future applications of this effect, especially in systemic infectious diseases such as sepsis and sepsis-associated encephalopathy. This review explores the possibility of using RIC as a treatment in more inflammation-related diseases, which will provide new ideas for the treatment of this kind of disease.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"9 2","pages":"77-87"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/15/5d/BC-9-77.PMC10419737.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9996323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Restlessness with manic episodes induced by right-sided multiple strokes after COVID-19 infection: A case report. COVID-19感染后右侧多发性卒中致躁动伴躁狂发作1例
IF 1.9 4区 医学
Brain Circulation Pub Date : 2023-04-01 DOI: 10.4103/bc.bc_103_22
Takahiko Nagamine
{"title":"Restlessness with manic episodes induced by right-sided multiple strokes after COVID-19 infection: A case report.","authors":"Takahiko Nagamine","doi":"10.4103/bc.bc_103_22","DOIUrl":"https://doi.org/10.4103/bc.bc_103_22","url":null,"abstract":"<p><p>Ischemic stroke is a major complication of coronavirus infection 2019 (COVID-19). During the COVID-19 pandemic, multiple strokes occurred in many elderly people. Among them, poststroke mood disorders such as depression are relatively common. However, restlessness with manic episodes has rarely been reported. We experienced an elderly patient who became manic shortly after recovering from COVID-19 infection, which turned out to be right-sided multiple strokes. The manic state improved as the strokes stabilized, suggesting that impaired blood flow was the cause of the manic symptoms. Primary mania increases blood flow in the left hemisphere, whereas right-sided strokes may relatively increase blood flow in the left hemisphere, which may have induced manic symptoms in this case. Multiple right-sided strokes after COVID-19 infection can cause mania, and the mechanism of poststroke mania needs to be investigated in the future.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"9 2","pages":"112-115"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/18/b8/BC-9-112.PMC10419738.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9996325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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