British journal of hospital medicine最新文献

{"title":"Impact of Labor Analgesia on Delivery Outcomes in Parturients With Gestational Diabetes Mellitus.","authors":"Yi Zheng, Mingyan Sheng, Xiaoyan Lu, Ming Wang, Zao Cen, Yisheng Zhang","doi":"10.31083/BJHM56149","DOIUrl":"https://doi.org/10.31083/BJHM56149","url":null,"abstract":"<p><strong>Aims/background: </strong>Although the efficacy of labor analgesia in pain relief is well-established, its impact on labor progression and maternal-neonatal outcomes remains inconclusive, particularly in parturients with gestational diabetes mellitus (GDM). This study aimed to examine the effects of labor analgesia on labor progression, delivery mode, and neonatal outcomes in parturients with GDM, thereby providing evidence to optimize clinical intervention strategies.</p><p><strong>Methods: </strong>A total of 201 GDM parturients meeting inclusion criteria at Beilun District People's Hospital of Ningbo City between 1 January 2023 and 31 December 2024, were retrospectively analyzed. Participants were allocated to the observation group (labor analgesia, <i>n</i> = 111) or the control group (routine delivery, <i>n</i> = 90) based on whether they received labor analgesia. Maternal clinical data, delivery mode, labor duration, maximum intrapartum temperature, postpartum hemorrhage, neonatal Apgar scores, and other obstetric outcomes were compared and analyzed retrospectively. Statistical analyses included independent sample <i>t</i>-tests, Mann-Whitney U test, Chi-squared tests, and Chi-squared correction.</p><p><strong>Results: </strong>Among the 111 parturients receiving labor analgesia, the 2-hour capillary blood glucose variation during labor was significantly higher in the epidural analgesia (EP) group compared with the combined spinal-epidural analgesia (CSEA) group (<i>p</i> < 0.001). The postpartum fasting plasma glucose (FPG) difference was also significantly greater (<i>p</i> < 0.001). The numerical rating scale (NRS) score after EP in the observation group was markedly lower than the pre-analgesia score (<i>p</i> < 0.001). The observation group demonstrated longer first and second stages of labor (<i>p</i> < 0.05), lower 2-hourly glucose fluctuations, higher maximum intrapartum temperature (<i>p</i> < 0.05) and soft tissue lacerations (<i>p</i> < 0.05), and increased rates of oxytocin use and episiotomy (<i>p</i> < 0.05). Furthermore, urinary ketone positivity, FPG difference, and 2-hour postprandial blood glucose (2hPBG) difference were lower in the observation group (<i>p</i> < 0.05), whereas postpartum day 1 C-reactive protein (CRP) levels were higher (<i>p</i> < 0.05). No significant differences were observed in delivery mode, postpartum urinary retention, postpartum hemorrhage, neonatal clavicle fracture, neonatal transfer, or incidence of patent foramen ovale and ductus arteriosus (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>Labor analgesia effectively alleviates labor pain and stabilizes intrapartum blood glucose fluctuations without increasing the risk of cesarean delivery or adverse maternal-neonatal outcomes. However, it may prolong labor duration, elevate intrapartum temperature, and increase oxytocin use, as well as the rates of episiotomy and soft birth canal lacerations. For GDM parturients receiving labor","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 7","pages":"56149"},"PeriodicalIF":1.7,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Outcomes of Uterine Artery Embolization in Adenomyosis With and Without Coexisting Uterine Fibroids or Ovarian Endometrioma: A Retrospective Clinical Analysis.","authors":"Zuofu Tian, Hao Liu, Chengjiang Xiao, Zhenbo Ouyang, Yunfan Wu, Wenjiang Wei","doi":"10.31083/BJHM56147","DOIUrl":"https://doi.org/10.31083/BJHM56147","url":null,"abstract":"<p><strong>Aims/background: </strong>Uterine artery embolization (UAE) is a minimally invasive therapeutic option for adenomyosis (AM). However, its clinical effectiveness in patients with comorbid gynecologic disorders remains unclear. This study aimed to evaluate the clinical efficacy of UAE in AM patients with or without concomitant uterine fibroids (UFs) or ovarian endometrioma (OE).</p><p><strong>Methods: </strong>A total of 243 women with AM who underwent UAE were retrospectively enrolled, including 141 patients with AM alone, 71 with concomitant UFs, and 31 with concomitant OE. Based on clinical response, 193 patients were classified as having effective treatment outcomes and 50 as ineffective. Baseline demographic and clinical characteristics were recorded. Symptom severity scale (SSS), health-related quality of life (HRQOL), and numerical rating scale (NRS) scores were assessed preoperatively, at 3 months after UAE, and at the last follow-up.</p><p><strong>Results: </strong>Significant differences in baseline age and cancer antigen 125 (CA125) levels were observed among the three groups (<i>p</i> < 0.05). Postoperatively, all groups showed significant reductions in SSS and NRS scores, as well as significant improvements in HRQOL scores, at both 3 months and the end of follow-up compared with baseline (all <i>p</i> < 0.001). At the final follow-up, patients in the AM + OE group exhibited significantly higher SSS and NRS scores as well as significantly lower HRQOL scores compared with the other two groups (<i>p</i> < 0.05). In contrast, no significant differences were observed between the simple AM and AM + UFs groups. Patients in the effective group were significantly older, had higher parity, lower CA125 levels, and showed a higher incidence of concomitant UFs but a lower incidence of OE compared with the ineffective group (all <i>p</i> < 0.05). HRQOL scores were significantly higher, and NRS scores were significantly lower in the effective group than in the ineffective group at both postoperative time points (all <i>p</i> < 0.001). The overall clinical efficacy rate was 79.42%, with no significant difference between the simple AM and AM + UFs groups (80.85% vs 88.73%, <i>p</i>_a = 0.15). However, the clinical efficacy rate was significantly lower in the AM + OE group (51.61%) than in both the simple AM (80.85%, <i>p</i> = 0.001) and AM + UFs (88.73%, <i>p</i> < 0.001) groups. Kaplan-Meier analysis indicated that concomitant OE was associated with an increased risk of treatment failure following UAE.</p><p><strong>Conclusion: </strong>UAE effectively alleviates symptoms and improves quality of life in patients with AM, particularly in those with isolated AM or concomitant UFs. However, clinical outcomes are less favorable in patients with concomitant OE, suggesting the need for individualized therapeutic strategies in this subgroup.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 7","pages":"56147"},"PeriodicalIF":1.7,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Use of Artificial Intelligence in Cancer Diagnosis.","authors":"Arka Banerjee, Daphne Theresa Chia, Kai Yuen Wong","doi":"10.31083/BJHM51300","DOIUrl":"https://doi.org/10.31083/BJHM51300","url":null,"abstract":"<p><p>Artificial intelligence (AI) is increasingly influencing cancer diagnostics, with ongoing advancements into more refined and advanced applications. This review examines current applications of AI in cancer diagnosis. AI has demonstrated considerable success in screening and diagnosis of a range of cancer types, including breast, colorectal, and skin cancer, but challenges with specificity and false-positive rates remain. Within radiology and histopathology, AI shows promise in identifying cancers and augmenting clinician performance. Natural language processing and AI-driven clinical documentation tools can expedite diagnosis by reducing administrative burden and extracting clinically meaningful data from unstructured records. Additionally, AI models using unimodal and multimodal data can improve patient prognostication and risk stratification. Despite these advances, challenges relating to deployment, bias, interpretability, accountability and real-world efficacy persist. Prospective validation and careful implementation are required to ensure safe, equitable, and effective adoption of AI in cancer diagnostics.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 7","pages":"51300"},"PeriodicalIF":1.7,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Reporting Quality of Randomized Controlled Trials on Peer Tutoring in Medical Education.","authors":"Xiaoli Zhang, Yanru Chen, Fuwu Wang, Yuji Guo, Jing Liu, Shangming Liu","doi":"10.31083/BJHM56148","DOIUrl":"10.31083/BJHM56148","url":null,"abstract":"<p><strong>Aims/background: </strong>Peer tutoring (PT) has been increasingly adopted as an innovative pedagogical approach in medical education. However, the methodological rigor and reporting quality of randomized controlled trials (RCTs) evaluating PT remain unclear. This study aimed to assess the reporting quality of PT-related RCTs using the Consolidated Standards of Reporting Trials (CONSORT) 2010 guidelines.</p><p><strong>Methods: </strong>A systematic search of PubMed, Embase, and Web of Science was conducted to identify RCTs that investigated PT interventions among medical students, focusing on publications after 2010. Eligible studies were screened independently by two researchers. Reporting quality was evaluated using the 28-item CONSORT 2010 checklist, and overall quality scores (OQSs) were calculated.</p><p><strong>Results: </strong>Forty-eight RCTs were included. The majority were published after 2015, with 37.5% between 2016 and 2020 and 35.4% between 2021 and 2025. Most studies were conducted in Europe or North America (75%), while 25% were from Asia. Approximately 81.3% of publications included in this analysis were published in journals with an impact factor below 4. The median OQS was 20 (range: 7-24). High compliance was observed for items such as abstract structure (95.8%), intervention details (100%), and outcome definition (100%), whereas randomization restriction (27.1%), allocation concealment (27.1%), implementation (25.0%), adverse event reporting (2.1%), and protocol availability (33.3%) were poorly reported.</p><p><strong>Conclusion: </strong>Despite the growing application of RCTs to evaluate PT in medical education, adherence to CONSORT 2010 remains suboptimal. Key methodological elements-particularly randomization, allocation concealment, and trial registration-were frequently underreported, which limits the interpretability and reproducibility of studies. Targeted training, stricter journal requirements, and education-specific CONSORT extensions are recommended to improve reporting quality in future PT-related RCTs.</p><p><strong>Registration: </strong>PROSPERO (CRD420261355464).</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 7","pages":"56148"},"PeriodicalIF":1.7,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal PET/CT Image Fusion-Derived Parameters and Biochemical Indices for Prognostic Monitoring in Nasopharyngeal Carcinoma: A Review.","authors":"Qidi Hu, Lili Kong, Jing Deng","doi":"10.31083/BJHM55375","DOIUrl":"https://doi.org/10.31083/BJHM55375","url":null,"abstract":"<p><p>Nasopharyngeal carcinoma is a common Epstein-Barr virus (EBV)-associated malignant tumour of the head and neck region. Accurate prognosis evaluation, risk stratification, and follow-up monitoring are essential for improving patient survival and quality of life. Multimodal positron emission tomography/computed tomography (PET/CT) image fusion has shown considerable promise in the diagnosis, staging, response assessment, and prognostic evaluation of nasopharyngeal cancer. This review examines the application of ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT)-derived parameters together with biochemical markers in prognostic models for nasopharyngeal cancer. Biochemical markers, including EBV DNA, lactate dehydrogenase, C-reactive protein, and inflammation-based indices associated with patient prognosis, are summarised. These markers may enhance the accuracy of prognostic assessment and provide critical supplementary information for imaging evaluation. Integrating imaging parameters with biochemical markers is expected to establish a more comprehensive prognostic evaluation system. Multimodal image fusion combined with systematic biochemical indicator monitoring offers novel concepts and techniques for the prognostic evaluation of nasopharyngeal carcinoma (NPC). Future research should focus on standardised PET/CT acquisition, validated segmentation methods, reliable biochemical assays, and prospective multicentre model validation to improve therapeutic outcomes and survival rates in affected patients.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 6","pages":"55375"},"PeriodicalIF":1.7,"publicationDate":"2026-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Updates in the Diagnosis and Management of Hypertension: A Review of Recent Guidelines.","authors":"Jay Kavia, Rahul Mittal, Joshua M Kaplan","doi":"10.31083/BJHM55374","DOIUrl":"10.31083/BJHM55374","url":null,"abstract":"<p><p>Hypertension is one of the leading contributors to global cardiovascular morbidity and mortality. Recent updates to major international guidelines have introduced changes in diagnostic thresholds, risk stratification, and treatment recommendations aimed at earlier detection and improved outcomes. This review summarises recent developments in the diagnosis and management of hypertension, comparing key recommendations from the American Heart Association (AHA)/American College of Cardiology (ACC), the European Society of Cardiology (ESC) and European Society of Hypertension (ESH), and the UK National Institute for Health and Care Excellence (NICE). Particular emphasis is placed on differences in diagnostic criteria, blood pressure targets, and evolving pharmacological and non-pharmacological management strategies. Updated guidelines increasingly promote out-of-office blood pressure monitoring and individualised treatment based on overall cardiovascular risk, comorbidities, and target-organ damage. Despite greater consensus on risk-based management, important regional differences remain, including the lower diagnostic threshold adopted in the United States and variation in treatment targets. Implementation in clinical practice continues to present challenges, as access to ambulatory blood pressure monitoring, healthcare resources, and patient adherence may limit uptake of guideline recommendations.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 6","pages":"55374"},"PeriodicalIF":1.7,"publicationDate":"2026-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Narrative Review of Early Palliative Care in Advanced Malignancy: Evidence, Challenges and Paths Ahead.","authors":"Freya Daws, Natasha Wiggins","doi":"10.31083/BJHM55141","DOIUrl":"10.31083/BJHM55141","url":null,"abstract":"<p><p>Early palliative care (EPC) has been shown to improve the quality of life of patients with advanced malignancies, although its role within the context of newer cancer therapeutics requires further research. Despite endorsement by national and international guidelines, EPC remains an aspirational ideal rather than a routine practice. Implementation is hindered by limited resources, clinician hesitancy to refer and patient- and family-related factors. To translate evidence into practice, future initiatives must focus on service innovations that operate within existing constraints. Stepped models, patient-reported outcome measures, telehealth, and machine learning represent promising approaches to achieving this goal. This review summarises the evidence surrounding EPC, outlines key barriers to its delivery and examines emerging strategies to improve its integration into oncological care.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 6","pages":"55141"},"PeriodicalIF":1.7,"publicationDate":"2026-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Obstructive Sleep Apnea in Patients With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.","authors":"Marco La Verde, Maria Maddalena Marrapodi, Luigi Della Corte, Antonietta Petillo, Mario Fordellone, Hande Uzunçıbuk, Silvia Piccolo, Giulia Maria Nicoletti, Giuseppe Minervini","doi":"10.31083/BJHM55373","DOIUrl":"10.31083/BJHM55373","url":null,"abstract":"<p><strong>Aims/background: </strong>Obstructive sleep apnea (OSA) and polycystic ovary syndrome (PCOS) share pathogenic pathways. Our review and meta-analysis estimated OSA prevalence in PCOS patients.</p><p><strong>Methods: </strong>Systematic search of four databases was performed: MEDLINE, Scopus, EMBASE, Cochrane Central Register of Controlled Trials from inception until 1 March 2024. Grey literature was explored via Google Scholar. The following keywords were adopted: \"obstructive sleep apnea\", \"OSA\", \"sleep-disordered breathing\", and \"polycystic ovary syndrome\". OSA was diagnosed through polysomnography. Observed heterogeneity was evaluated using both Cochran's Q test (<i>p</i> < 0.10) and the I² statistic. A random-effects model was applied when significant heterogeneity was detected, with the between-study variance (τ²) estimated using the DerSimonian-Laird method.</p><p><strong>Results: </strong>We included 16 studies in the qualitative analysis and 13 in the quantitative analysis, comprising a total of 230,293 patients, including 148,378 in the control group and 81,915 in the PCOS group. Under the common effect model, the OSA pooled risk ratio in the PCOS group was 2.53 (95% confidence interval [CI]: 2.19-2.92), and 3.55 (95% CI: 1.98-6.37) under the random-effects model. Individual risk ratio ranged between 1.50-25.58. Significant heterogeneity was observed (I² = 73.8%, τ² = 0.4605, <i>p</i> = 0.0004), suggesting potential publication bias based on funnel plot analysis.</p><p><strong>Conclusion: </strong>High prevalence of OSA was evidenced in PCOS women. These findings highlighted a significant association between these two conditions and the need for targeted screening or management in these high-risk patients. Further study to investigate these bidirectional relationships is needed.</p><p><strong>Systematic review registration: </strong>PROSPERO (CRD42024524008).</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 6","pages":"55373"},"PeriodicalIF":1.7,"publicationDate":"2026-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Perineural Dexamethasone on Preventing Post-Surgical Rebound Pain and Effects on Hyperglycaemia: A Meta-Analysis, Meta Regression and Trial Sequential Analysis.","authors":"Rahul Banerjee, Anindya Banerjee, Madhuchanda Chatterjee, Arnab Banerjee","doi":"10.31083/BJHM55376","DOIUrl":"10.31083/BJHM55376","url":null,"abstract":"<p><strong>Aims/background: </strong>Rebound pain is extreme pain occurring once the effects of a regional nerve block have subsided. We undertook a meta-analysis to assess the impact of perineural dexamethasone, as an adjunct to peripheral nerve block, on post-surgical rebound pain compared to local anaesthetic alone.</p><p><strong>Methods: </strong>The databases PubMed, Scopus and Cochrane Library were searched for randomised controlled trials, reporting rebound pain with perineural dexamethasone used as an adjunct to peripheral nerve blocks (from inception to 28 October 2025). The primary outcome was the incidence of rebound pain post-surgically; the secondary outcomes were onset of rebound pain (hours), pain scores at 24 and 48 hours, time until first analgesic request (hours), and incidence of hyperglycaemia.</p><p><strong>Results: </strong>Nine studies with 764 participants were included. Perineural dexamethasone significantly reduced the incidence of rebound pain (odds ratio [OR] = 5.00, 95% confidence interval [CI] 2.69-9.29, <i>p</i> < 0.00001, I² = 41%). The time to the first analgesic request was prolonged in the dexamethasone group (standardised mean differences [SMD] = -2.37, 95% CI -3.38- -1.36, <i>p</i> < 0.00001, I² = 77%). Perineural dexamethasone did not delay the onset of rebound pain, reduce pain scores at 24 and 48 hours, nor did it significantly alter blood sugar levels.</p><p><strong>Conclusion: </strong>This meta-analysis demonstrated that perineural dexamethasone is more effective than local anaesthetic alone in reducing the incidence of rebound pain and extending the time to the patients' first analgesic request. There was no significant difference in the onset of rebound pain, pain scores at 24 and 48 hours, nor alteration of blood sugar levels.</p><p><strong>Systematic review registration: </strong>PROSPERO (CRD42024545072).</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 6","pages":"55376"},"PeriodicalIF":1.7,"publicationDate":"2026-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Extremely Rare Case of a Follicular Thyroid Cancer Metastasis to the Ovary: A Case Report.","authors":"Zahra Aslam, Maya Uppal, Harpreet Uppal","doi":"10.31083/BJHM55372","DOIUrl":"10.31083/BJHM55372","url":null,"abstract":"<p><strong>Aims/background: </strong>Follicular thyroid cancer (FTC) is a well-differentiated, low-risk cancer of the thyroid gland accounting for approximately 10-15% of all thyroid cancers. The only definitive management of FTC is surgery. Whilst distant metastasis can occur, spread to the ovaries is rare, with only two reported cases. Therefore, we present the third known case of a patient with a primary follicular thyroid cancer that developed ovarian metastases and review the current literature.</p><p><strong>Case presentation: </strong>A 50-year-old female with a more than 10-year history of a multinodular goitre presented to the Ear, Nose and Throat Surgery, University Hospitals of North Midlands NHS Trust at a tertiary specialist centre with worsening compressive symptoms. A total thyroidectomy was performed and was histologically confirmed as a minimally invasive follicular thyroid cancer. She received radio-iodine ablation therapy. Unexpectedly, uptake was identified in the right ovary on a post-treatment (ablation) nuclear medicine (NM) thyroid I-131 scan and upon further imaging, a cyst was noted within the right ovary.</p><p><strong>Results: </strong>A bilateral salpingo-oophorectomy and hysterectomy were performed, which revealed a metastatic follicular thyroid carcinoma. Further post-op imaging was unremarkable, and the patient remains disease-free 18 months after her original thyroidectomy.</p><p><strong>Conclusion: </strong>Appropriate multidisciplinary team (MDT) discussion, as well as detailed imaging and biopsies if indicated, are paramount to obtaining an accurate diagnosis. Surgical resection and radioactive iodine treatment should be considered in appropriate cases in order to control local disease.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 6","pages":"55372"},"PeriodicalIF":1.7,"publicationDate":"2026-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}