British journal of hospital medicine最新文献

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Metformin: Not Just a Diabetes Treatment. 二甲双胍:不仅仅是一种糖尿病治疗药物。
IF 1.7 4区 医学
British journal of hospital medicine Pub Date : 2026-07-21 DOI: 10.31083/BJHM54156
Dipa Kamdar
{"title":"Metformin: Not Just a Diabetes Treatment.","authors":"Dipa Kamdar","doi":"10.31083/BJHM54156","DOIUrl":"https://doi.org/10.31083/BJHM54156","url":null,"abstract":"","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 7","pages":"54156"},"PeriodicalIF":1.7,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Platelet-To-Lactate Ratio Predicts In-Hospital Mortality in Patients With Sepsis-Induced Coagulopathy: A Retrospective Cohort Study. 血小板-乳酸比值预测脓毒症致凝血病患者的住院死亡率:一项回顾性队列研究
IF 1.7 4区 医学
British journal of hospital medicine Pub Date : 2026-07-21 DOI: 10.31083/BJHM52277
Shuai Mao, Xuan Zhang, Shengshu Wang, Yunzhang Zhao, Chao Lv, Yanzhu Yao, Yuyan Wang, Yifan Wang, Yong Xu, Tong Yin
{"title":"Platelet-To-Lactate Ratio Predicts In-Hospital Mortality in Patients With Sepsis-Induced Coagulopathy: A Retrospective Cohort Study.","authors":"Shuai Mao, Xuan Zhang, Shengshu Wang, Yunzhang Zhao, Chao Lv, Yanzhu Yao, Yuyan Wang, Yifan Wang, Yong Xu, Tong Yin","doi":"10.31083/BJHM52277","DOIUrl":"https://doi.org/10.31083/BJHM52277","url":null,"abstract":"<p><strong>Aims/background: </strong>Sepsis-induced coagulopathy (SIC) is a life-threatening complication with high mortality. The platelet count reflects coagulation status, and the lactate level indicates tissue hypoperfusion, although the prognostic value of these individual parameters is limited. The platelet-to-lactate ratio (PLAC) integrates these parameters, but its prognostic role in SIC is unclear. Here, we investigated the association between the PLAC and in-hospital mortality in patients with SIC.</p><p><strong>Methods: </strong>This retrospective cohort study included patients with SIC who were diagnosed after admission to the intensive care unit (ICU) of Chinese PLA General Hospital between December 2017 and October 2025. Multivariate Cox regression was used to assess the association between the PLAC and mortality. Restricted cubic spline (RCS) analysis was used to explore nonlinear relationships and threshold effects. The predictive performance of the PLAC was compared with that of the Sequential Organ Failure Assessment (SOFA) score, the SIC score, and the Charlson comorbidity index score using receiver operating characteristic (ROC) curves and the DeLong test.</p><p><strong>Results: </strong>Among 1722 patients with SIC, the in-hospital mortality was 26.2% (n = 452). Nonsurvivors had significantly lower PLAC values than did survivors (13.44 vs. 32.75, <i>p</i> < 0.001). Compared with the highest PLAC tertile, the middle and lowest tertiles had significantly higher mortality risk [adjusted hazard ratios (HRs): 1.701 and 3.501, respectively; both <i>p</i> < 0.05]. RCS analysis revealed a threshold effect at PLAC = 28. The area under the curve (AUC) for the PLAC was 0.711 (95% CI: 0.683-0.738), which was comparable to that of the SOFA score (<i>p</i> = 0.135) and superior to that of the SIC score and Charlson comorbidity index score (both <i>p</i> < 0.001). Subgroup analyses revealed a consistent prognostic value across most subgroups, with a significant interaction for coronary artery disease (<i>p</i> < 0.0001 for interaction) and Charlson score (<i>p</i> = 0.042).</p><p><strong>Conclusion: </strong>The PLAC is independently associated with in-hospital mortality in patients with SIC, with a clinically actionable threshold of 28. The PLAC is a simple biomarker that integrates coagulation and perfusion status and is a practical tool for risk stratification. However, multicenter prospective studies are needed to validate these findings.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 7","pages":"52277"},"PeriodicalIF":1.7,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Novel Chemiluminescent Immunoassay for Urinary LAM Detection Improves Tuberculosis Diagnosis in HIV Cohorts. 一种新的化学发光免疫分析法用于尿液LAM检测,提高了HIV队列中结核病的诊断。
IF 1.7 4区 医学
British journal of hospital medicine Pub Date : 2026-07-21 DOI: 10.31083/BJHM56189
Yu Li, Jinli Lou, Hongjuan Wei, Limei Sun, Yanhua Yu, Yanwei Hu
{"title":"A Novel Chemiluminescent Immunoassay for Urinary LAM Detection Improves Tuberculosis Diagnosis in HIV Cohorts.","authors":"Yu Li, Jinli Lou, Hongjuan Wei, Limei Sun, Yanhua Yu, Yanwei Hu","doi":"10.31083/BJHM56189","DOIUrl":"https://doi.org/10.31083/BJHM56189","url":null,"abstract":"<p><strong>Aims/background: </strong>Tuberculosis (TB) is a highly prevalent opportunistic infection and a leading cause of mortality worldwide, particularly among those living with human immunodeficiency virus (HIV). Among these patients, the diagnostic accuracy of conventional TB testing is generally limited by atypical clinical manifestations, the frequent occurrence of extrapulmonary TB, challenges in obtaining sputum samples, and consistently low bacterial loads in clinical specimens. Therefore, this study assesses the diagnostic performance of a novel chemiluminescence immunoassay (CLIA) for detecting urinary lipoarabinomannan (LAM) in individuals coinfected with HIV and TB.</p><p><strong>Methods: </strong>A prospective cohort study was conducted involving 297 people living with HIV (PLWH) recruited from Beijing Youan Hospital, Capital Medical University, China, between May 2021 and December 2024. By September 2025, when this analysis was finalized, all patients had received at least 6 months of follow-up. Of these, 76 patients had TB (34 definite cases and 42 probable cases), while 221 non-TB patients with confirmed alternative diagnoses were included as a control group. A novel double-antibody sandwich CLIA was specifically designed to detect the <i>Mycobacterium tuberculosis</i> LAM antigen in urine specimens. For comparative evaluation, all samples were concurrently analyzed using the commercially available Determine™ TB LAM Ag test (AlereLAM, Abbott Laboratories, USA). Investigators were blinded to the laboratory test results until the completion of enrollment, and laboratory technicians were blinded to patients' diagnoses throughout the study duration.</p><p><strong>Results: </strong>Receiver operating characteristic (ROC) analysis showed an area under the curve (AUC) of 0.925 at the optimal cutoff of 1.46. Median CLIA values increased in a graded manner across groups: 0.98 in the non-TB group, 1.96 in the probable TB group, and 4.46 in the definite-TB group (<i>p <</i> 0.001). Compared with AlereLAM, CLIA demonstrated significantly higher sensitivity (85.3% vs. 58.8%) but lower specificity (89.6% vs. 98.2%). Neither LAM-CLIA nor AlereLAM exhibited a significant association with patient cluster of differentiation (CD) 4<sup>+</sup> T cell counts (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>CLIA-based urinary LAM detection demonstrates superior sensitivity compared with conventional lateral flow assays, providing a rapid and quantitative approach for detecting HIV-associated TB. This method has significant potential to improve early TB detection in high-risk populations, particularly where culture-based methods are unavailable.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 7","pages":"56189"},"PeriodicalIF":1.7,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing Global, Regional, and National Burden of Depressive Disorder Attributable to Childhood Sexual Abuse and Bullying Victimization From 1990 to 2021: A Study on Individuals Aged 10-24 Years. 评估1990年至2021年儿童性虐待和欺凌受害者导致的全球、地区和国家抑郁症负担:一项针对10-24岁个体的研究
IF 1.7 4区 医学
British journal of hospital medicine Pub Date : 2026-07-21 DOI: 10.31083/BJHM56188
Yuning Ma, Qing Guan, Jinzhong Ji, Zujie Chen, Qiwei Ji, Gaozhan Ren, Mingxin Sun, Xiuquan Lin, Hao Zhou
{"title":"Assessing Global, Regional, and National Burden of Depressive Disorder Attributable to Childhood Sexual Abuse and Bullying Victimization From 1990 to 2021: A Study on Individuals Aged 10-24 Years.","authors":"Yuning Ma, Qing Guan, Jinzhong Ji, Zujie Chen, Qiwei Ji, Gaozhan Ren, Mingxin Sun, Xiuquan Lin, Hao Zhou","doi":"10.31083/BJHM56188","DOIUrl":"https://doi.org/10.31083/BJHM56188","url":null,"abstract":"<p><strong>Aims/background: </strong>This study aims to assess the burden of depressive disorder attributable to childhood sexual abuse (CSA) and bullying victimization (BV) among individuals aged 10-24 years from 1990 to 2021.</p><p><strong>Methods: </strong>Using the 2021 Global Burden of Disease (GBD) database, disability-adjusted life years (DALYs) for depressive disorder attributable to CSA or BV among the 10-24-year-old individuals from 1990 to 2021 were extracted. The 2021 global burden and trends in these disorders were assessed using the average annual percentage change (AAPC). Disease burden was further verified using cross-national inequalities and panel data models.</p><p><strong>Results: </strong>High socio-demographic index (SDI) regions experienced the most significant burden of depressive disorder attributable to CSA and BV among 10-24-year-old individuals in 2021. Females had a higher CSA-related depressive disorder burden, while males had a greater BV-related depressive disorder burden. From a global perspective, the age-standardized disability-adjusted life years rate (ASDR) for CSA-related depressive disorder remained stable from 1990 to 2021, though high SDI regions are increasing annually. Conversely, BV-associated ASDR increased globally, with high and low-middle SDI regions showing rates above the global average and rapid growth in high-SDI areas. Panel analysis showed inverse correlations between the DALY rate for depressive disorder and compulsory education duration, domestic general government health expenditure, and physician density, but a positive correlation with current health expenditure per capita (purchasing power parity [PPP]). Furthermore, BV-attributable depressive disorder DALYs correlated negatively with current health expenditure (% of gross domestic product [GDP]), while CSA-attributable depressive disorder DALYs correlated positively with hospital beds.</p><p><strong>Conclusion: </strong>The global burden of depressive disorder attributable to CSA among 10-24-year-old individuals remained stable, while the burden attributable to BV increased, and both showed significant disparities by gender and region. Globally, the heavier burden of depressive disorder in females was linked to CSA, and in males to BV. Geographically, the burden from both factors increased in high-SDI regions. Given substantial variations by gender, SDI, and geography, interventions should be tailored to national development levels and cultural contexts.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 7","pages":"56188"},"PeriodicalIF":1.7,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-World Treatment Practice and Survival Outcomes in Elderly Patients With Nasopharyngeal Carcinoma. 老年鼻咽癌患者的现实世界治疗实践和生存结果。
IF 1.7 4区 医学
British journal of hospital medicine Pub Date : 2026-07-21 DOI: 10.31083/BJHM56190
Zhenzhen Lu, Linfeng Guo, Ziqing You, Yifeng Yu, Sangang Wu, Yimin Li
{"title":"Real-World Treatment Practice and Survival Outcomes in Elderly Patients With Nasopharyngeal Carcinoma.","authors":"Zhenzhen Lu, Linfeng Guo, Ziqing You, Yifeng Yu, Sangang Wu, Yimin Li","doi":"10.31083/BJHM56190","DOIUrl":"https://doi.org/10.31083/BJHM56190","url":null,"abstract":"<p><strong>Aims/background: </strong>Elderly patients with nasopharyngeal carcinoma (NPC) generally experience inferior treatment outcomes compared to the younger population. Understanding the complex interplay among age, treatment modalities, and clinical outcomes is critical for developing evidence-based clinical guidelines for this demographic. This study aimed to evaluate treatment patterns, compliance, and clinical outcomes in elderly NPC patients within a real-world setting.</p><p><strong>Methods: </strong>We retrospectively included elderly patients (≥65 years) with NPC who received radiotherapy between January 2015 and December 2022. The primary endpoints were progression-free survival (PFS) and overall survival (OS). Statistical analyses were performed using the chi-square test, Kaplan-Meier method with log-rank test, and Cox proportional hazards model.</p><p><strong>Results: </strong>A total of 95 patients were included. Forty-two patients (44.2%) received induction chemotherapy (IC) followed by concurrent chemoradiotherapy (CCRT), 22 patients (23.2%) received CCRT alone, and 31 patients (32.6%) underwent radiotherapy alone. The CCRT completion rates were comparable between the IC group (64.3%) and the non-IC group (68.2%) (<i>p</i> = 0.755). Notably, 91 patients (95.7%) completed the recommended course of radiotherapy. The 5-year PFS and OS rates were 54.9% and 66.2%, respectively. Multivariate analysis identified age, gender, Adult Comorbidity Evaluation-27 score, Epstein-Barr Virus-deoxyribonucleic acid status, and treatment modality as independent prognostic factors. The results of multivariate prognostic analysis also showed that patients who did not receive CCRT had worse PFS (<i>p</i> = 0.029) and OS (<i>p</i> = 0.005) compared to those who received CCRT. However, no significant differences in PFS (<i>p</i> = 0.274) and OS (<i>p</i> = 0.594) were observed between the IC+CCRT and CCRT alone groups.</p><p><strong>Conclusion: </strong>Despite high adherence to recommended radiotherapy regimens, survival outcomes in elderly NPC patients remain suboptimal. Our findings indicate that CCRT significantly improves survival compared to radiotherapy alone. However, the addition of IC to CCRT did not confer a survival benefit over CCRT alone. These findings underscore the importance of individualized treatment planning and the necessity of considering the comprehensive health status of elderly NPC patients in clinical practice.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 7","pages":"56190"},"PeriodicalIF":1.7,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic Kidney Disease-Associated Cardiomyopathy: Mechanisms and Therapeutic Strategies. 慢性肾脏疾病相关心肌病:机制和治疗策略。
IF 1.7 4区 医学
British journal of hospital medicine Pub Date : 2026-07-21 DOI: 10.31083/BJHM51534
Konstantinos Grigoriou, Vasileios Lamprou, Anastasios Chatzichidiroglou, Panagiotis Theofilis, Panagiotis Iliakis, Anastasios Apostolos, Nikolaos Ktenopoulos, Efstratios Karagiannidis, Antonios P Antoniadis, Nikolaos Fragakis, Dimitrios Patoulias, Paschalis Karakasis
{"title":"Chronic Kidney Disease-Associated Cardiomyopathy: Mechanisms and Therapeutic Strategies.","authors":"Konstantinos Grigoriou, Vasileios Lamprou, Anastasios Chatzichidiroglou, Panagiotis Theofilis, Panagiotis Iliakis, Anastasios Apostolos, Nikolaos Ktenopoulos, Efstratios Karagiannidis, Antonios P Antoniadis, Nikolaos Fragakis, Dimitrios Patoulias, Paschalis Karakasis","doi":"10.31083/BJHM51534","DOIUrl":"https://doi.org/10.31083/BJHM51534","url":null,"abstract":"<p><p>Chronic kidney disease-associated cardiomyopathy (CKD-CM) is a term that captures the spectrum of myocardial disease that begins early in chronic kidney disease (CKD) and progresses as kidney function declines. Historically described as uremic cardiomyopathy, the condition was associated with severe left ventricular hypertrophy and fibrosis in patients with kidney failure. However, functional abnormalities and myocardial injury have been shown to begin much earlier, with diffuse interstitial fibrosis preceding overt hypertrophy or reduced ejection fraction. Fibrosis drives heart failure with preserved ejection fraction (HFpEF)-like physiology and atrial fibrillation and increases arrhythmic risk. In this review, we describe the multiple interacting mechanisms, including abnormal loading, neurohormonal activation, metabolic and inflammatory stress, mineral bone disorder, and microvascular dysfunction. We summarize imaging findings across CKD stages and describe established and emerging therapeutic strategies. A better understanding of CKD-CM pathogenesis is likely to enable early intervention and prevention, with successful outcomes measured by reduced progression to severe cardiomyopathy and lower cardiovascular mortality in CKD.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 7","pages":"51534"},"PeriodicalIF":1.7,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrating Mental Health Into Cardiovascular Care: Insight From the 2025 European Society of Cardiology Clinical Consensus Statement. 将心理健康纳入心血管护理:来自2025年欧洲心脏病学会临床共识声明的见解
IF 1.7 4区 医学
British journal of hospital medicine Pub Date : 2026-07-21 DOI: 10.31083/BJHM53894
Kawser Ahmed, Emil Manzoor Ahmed, Hamna Nazeer
{"title":"Integrating Mental Health Into Cardiovascular Care: Insight From the 2025 European Society of Cardiology Clinical Consensus Statement.","authors":"Kawser Ahmed, Emil Manzoor Ahmed, Hamna Nazeer","doi":"10.31083/BJHM53894","DOIUrl":"https://doi.org/10.31083/BJHM53894","url":null,"abstract":"","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 7","pages":"53894"},"PeriodicalIF":1.7,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Pitavastatin Versus Atorvastatin Therapy With Glycaemic Control and New-Onset Diabetes in Older Adults With Atherosclerotic Cardiovascular Disease. 匹伐他汀与阿托伐他汀治疗与老年动脉粥样硬化性心血管疾病患者血糖控制和新发糖尿病的关系
IF 1.7 4区 医学
British journal of hospital medicine Pub Date : 2026-07-20 DOI: 10.31083/BJHM56151
Hongwen Li, Jie Li
{"title":"Association of Pitavastatin Versus Atorvastatin Therapy With Glycaemic Control and New-Onset Diabetes in Older Adults With Atherosclerotic Cardiovascular Disease.","authors":"Hongwen Li, Jie Li","doi":"10.31083/BJHM56151","DOIUrl":"https://doi.org/10.31083/BJHM56151","url":null,"abstract":"<p><strong>Aims/background: </strong>Statins are first-line therapy for atherosclerotic cardiovascular disease (ASCVD), but their differential effects on glucose metabolism, particularly in the elderly, remain a clinical concern. This study aimed to compare the effects of pitavastatin versus atorvastatin on glucose metabolism in elderly patients with ASCVD.</p><p><strong>Methods: </strong>In this retrospective cohort study conducted at Public Health Clinical Center Affiliated to Shandong University between January 2022 and December 2023, 126 elderly ASCVD patients aged ≥60 years were included and allocated to either the pitavastatin group (4 mg/day, <i>n</i> = 58) or the atorvastatin group (20 mg/day, <i>n</i> = 68). Fasting blood samples were collected at baseline and after 12 months of treatment to measure lipid profiles, glucose metabolism parameters, liver function, and renal function.</p><p><strong>Results: </strong>After treatment, the pitavastatin group demonstrated significantly higher levels of high-density lipoprotein cholesterol (HDL-C) (1.41 ± 0.30 mmol/L vs. 1.26 ± 0.28 mmol/L, <i>p</i> = 0.005). Regarding glucose metabolism, the pitavastatin group showed lower fasting plasma glucose (5.85 ± 0.70 mmol/L vs. 6.19 ± 0.85 mmol/L, <i>p</i> = 0.018) and glycated hemoglobin (6.10 ± 0.42% vs. 6.33 ± 0.51%, <i>p</i> = 0.009). No cases of new-onset diabetes were detected in the pitavastatin group, as compared to the 10.29% rate observed in the atorvastatin group. Multivariate logistic regression analysis confirmed pitavastatin as a protective factor against new-onset diabetes (odds ratio = 0.212, <i>p</i> = 0.018).</p><p><strong>Conclusion: </strong>Compared with atorvastatin, pitavastatin may be associated with better glycemic outcomes and a lower risk of new-onset diabetes in elderly ASCVD patients, supporting its consideration in clinical practice where glycemic control is a concern.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 7","pages":"56151"},"PeriodicalIF":1.7,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Perineal Heat Stimulation Combined With Massage Pre-Adaptation on Perineal Injury and Maternal Psychological Well-Being in Primiparous Women. 会阴热刺激联合按摩预适应对初产妇会阴损伤及产妇心理健康的影响。
IF 1.7 4区 医学
British journal of hospital medicine Pub Date : 2026-07-20 DOI: 10.31083/BJHM56150
Yun Wang, Jing Yin, Jingyu Wu, Tingting Wei, Zhenni Ai, Yi Niu, Ting Wei
{"title":"Effects of Perineal Heat Stimulation Combined With Massage Pre-Adaptation on Perineal Injury and Maternal Psychological Well-Being in Primiparous Women.","authors":"Yun Wang, Jing Yin, Jingyu Wu, Tingting Wei, Zhenni Ai, Yi Niu, Ting Wei","doi":"10.31083/BJHM56150","DOIUrl":"https://doi.org/10.31083/BJHM56150","url":null,"abstract":"<p><strong>Aims/background: </strong>Perineal injuries remain a common complication of vaginal birth, particularly among primiparous women. This study assessed the effects of a perineal heat stimulation-massage plus pre-adaptation protocol, started at 34 weeks of gestation, on perineal outcomes and maternal psychological well-being in primiparous women.</p><p><strong>Methods: </strong>This retrospective cohort study enrolled 500 primiparous women who delivered at Jiangxi Maternal and Child Health Hospital between May 2025 and October 2025. Participants were divided into an intervention group (n = 247) and a control group (n = 253) based on antenatal records and self-reports of receiving the structured protocol. Outcomes compared between the two groups included perineal injury, duration of all labor stages, postpartum blood loss within 2 hours, perineal pain at 48 hours, neonatal Apgar scores, and maternal psychological well-being assessed using the Childbirth Self-Efficacy Inventory (CBSEI) and the State-Trait Anxiety Inventory (STAI).</p><p><strong>Results: </strong>Compared with routine care, the intervention group had a significantly better rate of intact perineum (34.01% vs. 15.02%, <i>p</i> < 0.001) and lower rates of both episiotomy (36.03% vs. 46.25%, <i>p</i> = 0.020) and perineal tears (29.96% vs. 38.74%, <i>p</i> = 0.039). Labor progressed more efficiently in the intervention group, with shorter median durations of the first (439 vs. 514 min), second (55 vs. 74 min), and third stages of labor (8 vs. 12 min). The intervention group also had reduced median postpartum blood loss within 2 hours (233 vs. 244 mL) and lower perineal pain at 48 hours (Visual Analog Scale [VAS] 3 vs. 4; <i>p</i> < 0.001). Furthermore, women in the intervention group reported significantly higher childbirth self-efficacy (CBSEI, 108 vs. 94 scores, <i>p</i> < 0.001) and lower state anxiety (STAI 35 vs. 41 scores, <i>p</i> < 0.001). The two groups did not differ in neonatal outcomes, including Apgar scores.</p><p><strong>Conclusion: </strong>The \"antenatal heat stimulation-massage combined pre-adaptation protocol\" was associated with reduced perineal injury and more efficient labor, along with lower postpartum distress and improved childbirth experience through psychological empowerment, without adverse effects on neonatal outcomes. These observations support the approach as a practical, non-pharmacological antenatal care framework and inform future prospective studies assessing the integrated mind-body preparation model in maternity care.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 7","pages":"56150"},"PeriodicalIF":1.7,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the Educational Quality and Reliability of Cardiopulmonary Resuscitation Training Videos on YouTube™. YouTube™心肺复苏培训视频教学质量与可靠性评价
IF 1.7 4区 医学
British journal of hospital medicine Pub Date : 2026-07-20 DOI: 10.31083/BJHM51256
Süleyman Nogay, Turgut Dolanbay, Bilgehan Demir, Bilal Kartal, Asiye Özkan
{"title":"Evaluation of the Educational Quality and Reliability of Cardiopulmonary Resuscitation Training Videos on YouTube™.","authors":"Süleyman Nogay, Turgut Dolanbay, Bilgehan Demir, Bilal Kartal, Asiye Özkan","doi":"10.31083/BJHM51256","DOIUrl":"https://doi.org/10.31083/BJHM51256","url":null,"abstract":"<p><strong>Aims/background: </strong>Cardiac arrest is a leading cause of mortality worldwide, and early, high-quality cardiopulmonary resuscitation (CPR) is critical for survival. With increasing use of digital media, YouTube™ has become a common resource for CPR education. However, the educational quality and scientific reliability of these videos remain inconsistent. This study aimed to evaluate the educational quality, reliability, and technical adequacy of CPR training videos on YouTube™ using tools and an evaluation index.</p><p><strong>Methods: </strong>A total of 120 CPR-related YouTube™ videos were analyzed. Videos were assessed using four validated tools: Modified DISCERN Scale (MDS), Journal of the American Medical Association (JAMA) scoring system, Global Quality Scale (GQS), and a newly developed evaluation index [cardiopulmonary resuscitation-video evaluation index (CPR-VEI)]. Video duration, views, likes, and uploader type were recorded, and analyses used nonparametric tests and Spearman correlation.</p><p><strong>Results: </strong>Institutionally produced videos demonstrated significantly higher view counts (<i>p</i> = 0.008) as well as higher JAMA (<i>p</i> < 0.001), CPR-VEI (<i>p</i> = 0.020), and MDS (<i>p</i> = 0.031) scores compared with individually uploaded content. Intermediate-duration videos demonstrated significantly higher CPR-VEI, GQS, and MDS scores compared with short-duration videos, while long-duration videos showed higher numbers of likes. Correlation analysis revealed strong positive associations between CPR-VEI and GQS and MDS scores, and a moderate positive correlation with the JAMA score.</p><p><strong>Conclusion: </strong>CPR training videos on YouTube™ exhibit substantial variability in educational quality and reliability. Institutionally produced videos demonstrated higher quality and reliability, while intermediate-duration videos showed higher educational scores and long-duration videos demonstrated greater engagement. However, popularity metrics such as views and likes did not reliably reflect educational quality. These findings support the role of guideline-based, technology-enhanced learning as an essential component of contemporary CPR education.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"87 7","pages":"51256"},"PeriodicalIF":1.7,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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