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Biomedicine / [publiee pour l'A.A.I.C.I.G.]最新文献

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Glycogenolysis-induced acceleration of "de novo" purine synthesis in mouse liver. 糖原溶解诱导的小鼠肝脏“从头”嘌呤合成加速。
Biomedicine / [publiee pour l'A.A.I.C.I.G.] Pub Date : 1981-05-01
S Brosh, P Boer, O Sperling
{"title":"Glycogenolysis-induced acceleration of \"de novo\" purine synthesis in mouse liver.","authors":"S Brosh, P Boer, O Sperling","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9217,"journal":{"name":"Biomedicine / [publiee pour l'A.A.I.C.I.G.]","volume":"35 2","pages":"50-1"},"PeriodicalIF":0.0,"publicationDate":"1981-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17329114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Antitoxoplasma IgM studied by indirect immunofluorescence and hemagglutination: elimination of false positives and negatives by adsorption of IgG on immobilized protein A]. [间接免疫荧光和血凝研究抗弓形虫IgM:通过固定蛋白A吸附IgG消除假阳性和阴性]。
Biomedicine / [publiee pour l'A.A.I.C.I.G.] Pub Date : 1981-05-01
R Robert, D Chabasse, P Hocquet
{"title":"[Antitoxoplasma IgM studied by indirect immunofluorescence and hemagglutination: elimination of false positives and negatives by adsorption of IgG on immobilized protein A].","authors":"R Robert, D Chabasse, P Hocquet","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9217,"journal":{"name":"Biomedicine / [publiee pour l'A.A.I.C.I.G.]","volume":"35 2","pages":"61-5"},"PeriodicalIF":0.0,"publicationDate":"1981-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18067355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dihydropteridine-reductase activity in breast cancer. Preliminary report. 乳腺癌中的二氢蝶啶还原酶活性。初步报告。
Biomedicine / [publiee pour l'A.A.I.C.I.G.] Pub Date : 1981-05-01
J L Dhondt, J Bonneterre, J P Farriaux, J Lefebvre, A Demaille
{"title":"Dihydropteridine-reductase activity in breast cancer. Preliminary report.","authors":"J L Dhondt,&nbsp;J Bonneterre,&nbsp;J P Farriaux,&nbsp;J Lefebvre,&nbsp;A Demaille","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The dihydropteridine-reductase activity was measured in 206 breast cancers. Large variations were found: 6% of tumors showing high values closed to those noted in liver, whereas the main group has activities of same magnitude of that in cultured fibroblasts. Significant correlation appeared between dihydropteridine-reductase activities and hormonal dependence, as measured by cytosolic estrogen receptor sites.</p>","PeriodicalId":9217,"journal":{"name":"Biomedicine / [publiee pour l'A.A.I.C.I.G.]","volume":"35 2","pages":"58-60"},"PeriodicalIF":0.0,"publicationDate":"1981-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17329807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of bacterial endotoxin on lysosomal enzyme activities of normal and mucolipidosis III fibroblasts. 细菌内毒素对正常和粘脂病III型成纤维细胞溶酶体酶活性的影响。
Biomedicine / [publiee pour l'A.A.I.C.I.G.] Pub Date : 1981-05-01
P Di Natale, M Stabile, L Ronsisvalle, R Utili
{"title":"Effect of bacterial endotoxin on lysosomal enzyme activities of normal and mucolipidosis III fibroblasts.","authors":"P Di Natale,&nbsp;M Stabile,&nbsp;L Ronsisvalle,&nbsp;R Utili","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of bacterial endotoxin (LPS) on lysosomal enzyme activities of fibroblasts from normals and mucolipidosis III patients was investigated. Exposure of normal fibroblasts to LPS for 24 hours resulted in enhanced intracellular activities of beta-glucuronidase, beta-galactosidase, alpha-L-iduronidase and beta-N-acetylglucosaminidase. Endotoxin also led to an increased extracellular activity of beta-N-acetylglucosaminidase. In contrast, mucolipidosis III fibroblasts did not show either intracellular or extracellular increase of lysosomal hydrolases after LPS treatment. Difference in cellular responsiveness to LPS may be related to the mechanism of LPS-cell interaction.</p>","PeriodicalId":9217,"journal":{"name":"Biomedicine / [publiee pour l'A.A.I.C.I.G.]","volume":"35 2","pages":"46-9"},"PeriodicalIF":0.0,"publicationDate":"1981-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18273070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cadaver nerve allografts in dogs. 狗的尸体神经异体移植。
Biomedicine / [publiee pour l'A.A.I.C.I.G.] Pub Date : 1981-05-01
R Singh, H M Vriesendorp, K Mechelse, S Stefanko
{"title":"Cadaver nerve allografts in dogs.","authors":"R Singh,&nbsp;H M Vriesendorp,&nbsp;K Mechelse,&nbsp;S Stefanko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cadaver nerve allografts were studied in major histocompatibility complex-identical beagle donor/recipient combinations. Grafts were removed 3 and 6 hours after the death of the donor, preserved at -70 degrees C and transplanted as 7 cm long grafts at a later date. Graft function and histology was evaluated 9 to 11 months after transplantation by electromyographic examination and histological studies, respectively. Cadaver nerve allografts removed 3 and 6 hours after death show exactly the same excellent regeneration as the freshly removed cryopreserved nerve allografts in major histocompatibility complex identical combinations. This information is of value for future attempts to establish nerve banks of a many as possible different major histocompatibility types. Such banks will be required to accommodate the necessary donor/recipient matching for clinical nerve allografting.</p>","PeriodicalId":9217,"journal":{"name":"Biomedicine / [publiee pour l'A.A.I.C.I.G.]","volume":"35 2","pages":"67-70"},"PeriodicalIF":0.0,"publicationDate":"1981-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18273073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumor promoting agent induces lymphocyte mitogenic factor. 促瘤剂诱导淋巴细胞有丝分裂因子。
Biomedicine / [publiee pour l'A.A.I.C.I.G.] Pub Date : 1981-03-01
S K Sundar, D V Ablashi, P H Levine, W C Wallen, G R Armstrong
{"title":"Tumor promoting agent induces lymphocyte mitogenic factor.","authors":"S K Sundar,&nbsp;D V Ablashi,&nbsp;P H Levine,&nbsp;W C Wallen,&nbsp;G R Armstrong","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Human peripheral mononuclear cells treated with tumor promoting agent, 12-O-tetradecanoyl phorbol 13-acetate (TPA), released a soluble lymphocyte mitogenic factor (MF). The MF was found to be a protein capable of eliciting a proliferative response in normal human lymphocytes within 40-46 hours. The MF was detected in the culture supernatant fluid as early as 12 hours after TPA treatment and reached maximum at 48 hours. The biochemical characterization of MF is under active investigation.</p>","PeriodicalId":9217,"journal":{"name":"Biomedicine / [publiee pour l'A.A.I.C.I.G.]","volume":"35 1","pages":"11-3"},"PeriodicalIF":0.0,"publicationDate":"1981-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18021045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Flow cytofluorometric analysis of the effects of new nitrosourea derivatives on proliferation of EMT 6 tumor cells "in vitro". 新型亚硝基脲衍生物对emt6肿瘤细胞“体外”增殖影响的流式细胞荧光分析。
Biomedicine / [publiee pour l'A.A.I.C.I.G.] Pub Date : 1981-03-01
M N Vlaeminck, M Collyn-d'Hooghe, P Cappelaere, G Biserte, J Oiry, J L Montero, J L Imbach
{"title":"Flow cytofluorometric analysis of the effects of new nitrosourea derivatives on proliferation of EMT 6 tumor cells \"in vitro\".","authors":"M N Vlaeminck,&nbsp;M Collyn-d'Hooghe,&nbsp;P Cappelaere,&nbsp;G Biserte,&nbsp;J Oiry,&nbsp;J L Montero,&nbsp;J L Imbach","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Examined by flow cytofluorometric analysis, the DNA distribution of EMT 6 tumor cells was highly perturbed after one hour of in vitro incubation with: RPCNU, RFCNU, chlorozotocin (CZT) or 185 (CNCC), four new nitrosourea derivatives. After the treatment with chlorozotocin (20 micrograms/ml) and CNCC (50 micrograms/ml), most of cells were in G2 + M phase and this accumulation lasted more than 48 hours without any restoration before 72 hours. RPCNU (20 micrograms/ml) and RFCNU (50 and 65 micrograms/ml) induced and accumulation of cells in G2 + M phase during 24 hours. The normal state was regained after 48 hours. These reduced rate of progression of the cells through S phase and the G2 block observed after exposure to the new compounds, should, in part, explain their antitumoral activity.</p>","PeriodicalId":9217,"journal":{"name":"Biomedicine / [publiee pour l'A.A.I.C.I.G.]","volume":"35 1","pages":"27-9"},"PeriodicalIF":0.0,"publicationDate":"1981-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18063805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of juvenile essential hypertension: implications of erythrocyte net Na+, K+ flux measurement. 1例青少年原发性高血压:红细胞净Na+、K+通量测定的意义。
Biomedicine / [publiee pour l'A.A.I.C.I.G.] Pub Date : 1981-03-01
J L Elghozi, G Dagher, R P Garay, D Vasmant, F Girard, P Meyer
{"title":"A case of juvenile essential hypertension: implications of erythrocyte net Na+, K+ flux measurement.","authors":"J L Elghozi,&nbsp;G Dagher,&nbsp;R P Garay,&nbsp;D Vasmant,&nbsp;F Girard,&nbsp;P Meyer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In recent studies were reported an inherited membrane defect which is closely related to the development of essential hypertension. This abnormality consists of a functional deficiency in the Na+--K+ co-transport mechanism in erythrocytes of essential hypertensives and some normotensives born of hypertensive parents. Here we report a case of juvenile essential hypertension including familial erythrocyte Na+, K+ measurements. The 2-year-old boy had essential hypertension and bore the abnormality, with no compensatory activity of the Na+, K+ pump. The mother had developed hypertension during pregnancy. She also bore the erythrocyte abnormality as the net Na+/K+ flux ratio was reduced. One sister bore the same abnormality without hypertension but a complete analysis of Na+ extrusion mechanisms in this patient demonstrated a compensatory effect of the Na+, K+ pump activity. Other members of the family were normotensive without the flux abnormality. It appears therefore that erythrocyte flux measurements might be of diagnostic and genetic interest in juvenile hypertension.</p>","PeriodicalId":9217,"journal":{"name":"Biomedicine / [publiee pour l'A.A.I.C.I.G.]","volume":"35 1","pages":"4-6"},"PeriodicalIF":0.0,"publicationDate":"1981-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18250277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"In vitro" effect of levamisole on macrophage migration inhibition in bovine gamma-globulin sensitized rats. 左旋咪唑对牛γ -球蛋白致敏大鼠巨噬细胞迁移抑制的“体外”效应。
Biomedicine / [publiee pour l'A.A.I.C.I.G.] Pub Date : 1981-03-01
B Burek
{"title":"\"In vitro\" effect of levamisole on macrophage migration inhibition in bovine gamma-globulin sensitized rats.","authors":"B Burek","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9217,"journal":{"name":"Biomedicine / [publiee pour l'A.A.I.C.I.G.]","volume":"35 1","pages":"6-7"},"PeriodicalIF":0.0,"publicationDate":"1981-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17231077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tamm-Horsfall protein and erythrocyte ghosts immunologically cross-react. Tamm-Horsfall蛋白与红细胞鬼免疫交叉反应。
Biomedicine / [publiee pour l'A.A.I.C.I.G.] Pub Date : 1981-03-01
L Hartmann, J Delaunay, M P Ollier-Hartmann, A Bringuier, G Richet
{"title":"Tamm-Horsfall protein and erythrocyte ghosts immunologically cross-react.","authors":"L Hartmann,&nbsp;J Delaunay,&nbsp;M P Ollier-Hartmann,&nbsp;A Bringuier,&nbsp;G Richet","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Antisera were raised in the rabbit against human Tamm-Horsfall protein (THP) and erythrocyte ghosts. They were purified and exhausted with serumalbumin. Using a radioimmunoassay, antisera against THP allowed to detect in erythrocyte ghosts 41 ng of a reaction material per mg membrane protein. Ouchterlony double diffusion technique showed a similar corss-reaction and, conversely, a cross-reaction between THP and antisera to erythrocyte ghosts. These data support the view that red cell membrane contains a compound related to THP.</p>","PeriodicalId":9217,"journal":{"name":"Biomedicine / [publiee pour l'A.A.I.C.I.G.]","volume":"35 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"1981-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17838710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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