乳腺癌中的二氢蝶啶还原酶活性。初步报告。

Biomedicine / [publiee pour l'A.A.I.C.I.G.] Pub Date : 1981-05-01

J L Dhondt, J Bonneterre, J P Farriaux, J Lefebvre, A Demaille

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引用次数: 0

摘要

在206例乳腺癌中测量了二氢蝶啶还原酶的活性。发现了很大的差异:6%的肿瘤显示出与肝脏中所注意到的高值，而主要组的活性与培养成纤维细胞的活性相同。二氢蝶啶还原酶活性与激素依赖性之间存在显著相关性，通过细胞质雌激素受体位点测量。

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Dihydropteridine-reductase activity in breast cancer. Preliminary report.

The dihydropteridine-reductase activity was measured in 206 breast cancers. Large variations were found: 6% of tumors showing high values closed to those noted in liver, whereas the main group has activities of same magnitude of that in cultured fibroblasts. Significant correlation appeared between dihydropteridine-reductase activities and hormonal dependence, as measured by cytosolic estrogen receptor sites.

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Biomedicine / [publiee pour l'A.A.I.C.I.G.]

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