Brain StimulationPub Date : 2025-01-01DOI: 10.1016/j.brs.2024.12.040
Leo Tomasevic
{"title":"Using the spatio-temporal specificity of the mu-rhythm shape for online phase detection","authors":"Leo Tomasevic","doi":"10.1016/j.brs.2024.12.040","DOIUrl":"10.1016/j.brs.2024.12.040","url":null,"abstract":"","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"18 1","pages":"Page 226"},"PeriodicalIF":7.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143478797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brain StimulationPub Date : 2025-01-01DOI: 10.1016/j.brs.2024.12.074
Harold Sackeim
{"title":"Impact of one-year VNS therapy on daily function and quality of life in markedly treatment-resistant major depression: results from the RECOVER trial","authors":"Harold Sackeim","doi":"10.1016/j.brs.2024.12.074","DOIUrl":"10.1016/j.brs.2024.12.074","url":null,"abstract":"","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"18 1","pages":"Page 238"},"PeriodicalIF":7.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143480117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cellular Mechanisms of Transcranial Magnetic Stimulation (TMS) Activation of Purkinje Neurons in the Cerebellum","authors":"Yoshio Okada , Chunling Dong , Sergey Makaroff , Padmavathi Sundaram","doi":"10.1016/j.brs.2024.12.011","DOIUrl":"10.1016/j.brs.2024.12.011","url":null,"abstract":"","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"18 1","pages":"Page 217"},"PeriodicalIF":7.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143480327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brain StimulationPub Date : 2025-01-01DOI: 10.1016/j.brs.2024.12.046
Katy Stimpson , T.J. Ford , Adi Maron-Katz , Michael Feyder , Danielle DeSouza , David Carreon , Eleanor Cole , Brandon Bentzley
{"title":"Magnus Neuromodulation System with Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT) as a Personalized Continuation Therapy for Depression: An Open-Label Pilot Trial","authors":"Katy Stimpson , T.J. Ford , Adi Maron-Katz , Michael Feyder , Danielle DeSouza , David Carreon , Eleanor Cole , Brandon Bentzley","doi":"10.1016/j.brs.2024.12.046","DOIUrl":"10.1016/j.brs.2024.12.046","url":null,"abstract":"","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"18 1","pages":"Pages 228-229"},"PeriodicalIF":7.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143480719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brain StimulationPub Date : 2025-01-01DOI: 10.1016/j.brs.2025.01.003
Runhao Lu , Elizabeth Michael , Catriona L. Scrivener , Jade B. Jackson , John Duncan , Alexandra Woolgar
{"title":"Parietal alpha stimulation causally enhances attentional information coding in evoked and oscillatory activity","authors":"Runhao Lu , Elizabeth Michael , Catriona L. Scrivener , Jade B. Jackson , John Duncan , Alexandra Woolgar","doi":"10.1016/j.brs.2025.01.003","DOIUrl":"10.1016/j.brs.2025.01.003","url":null,"abstract":"<div><h3>Background</h3><div>Selective attention is a fundamental cognitive mechanism that allows people to prioritise task-relevant information while ignoring irrelevant information. Previous research has suggested key roles of parietal event-related potentials (ERPs) and alpha oscillatory responses in attention tasks. However, the informational content of these signals is less clear, and their causal effects on the coding of multiple task elements are yet unresolved.</div></div><div><h3>Objective</h3><div>To test the causal roles of alpha oscillations and ERPs in coding different types of attentional information (<em>where to attend</em>, <em>what to attend to</em>, and <em>features of the</em> <em>visual stimulus</em>).</div></div><div><h3>Methods</h3><div>We first used EEG to examine the temporal dynamics of alpha oscillations and ERPs in coding attentional information. Then, we applied rhythmic-TMS (rh-TMS) at individual alpha frequency over the right intraparietal sulcus (IPS), while concurrently measuring EEG, to causally manipulate parietal alpha power and ERPs and investigate their roles in coding multiple task features in a selective attention task.</div></div><div><h3>Results</h3><div>EEG-only data suggested that ERPs coded all three types of task-relevant information with distinct temporal dynamics, while alpha oscillations carried information regarding both where to attend and what to attend to. TMS-EEG results indicated that, compared to arrhythmic-TMS, alpha rh-TMS increased alpha power and inter-trial phase coherence and yielded more negative posterior-contralateral ERPs. Moreover, alpha rh-TMS specifically and causally improved multivariate decoding of information about <em>where to attend</em> (but not <em>what to attend to</em> or <em>visual feature information</em>) during task performance, with decoding improvements predicting changes in behavioural performance.</div></div><div><h3>Conclusions</h3><div>These findings illuminate the dynamics with which the complementary aspects of a selective attention task are encoded in evoked and oscillatory brain activity. Moreover, they reveal a specific and causal role of IPS-controlled evoked and oscillatory activity in carrying behaviour-driving information exclusively about where to focus attention.</div></div>","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"18 1","pages":"Pages 114-127"},"PeriodicalIF":7.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142944457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brain StimulationPub Date : 2025-01-01DOI: 10.1016/j.brs.2025.01.005
Noah Stapper , Jordan Kohn , Lindsay Benster , Hadley Daniels , Vanessa Tello , Aashi Patel , Vidhi Oswal , Louise Stolz , Mohsen Poorganji , Yinming Sun , Zafiris J. Daskalakis , Lawrence G. Appelbaum , Cory R. Weissman
{"title":"Repetitive transcranial magnetic stimulation for the treatment of suicidal ideation in a naturalistic setting","authors":"Noah Stapper , Jordan Kohn , Lindsay Benster , Hadley Daniels , Vanessa Tello , Aashi Patel , Vidhi Oswal , Louise Stolz , Mohsen Poorganji , Yinming Sun , Zafiris J. Daskalakis , Lawrence G. Appelbaum , Cory R. Weissman","doi":"10.1016/j.brs.2025.01.005","DOIUrl":"10.1016/j.brs.2025.01.005","url":null,"abstract":"","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"18 1","pages":"Pages 141-143"},"PeriodicalIF":7.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143000406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brain StimulationPub Date : 2025-01-01DOI: 10.1016/j.brs.2025.01.015
Ziping Huang , Charalambos C. Charalambous , Mengyue Chen , Taewon Kim , Estate Sokhadze , Allen Song , Sin-Ho Jung , Shashank Shekhar , Jody A. Feld , Xiaoning Jiang , Wuwei Feng
{"title":"Low intensity focused ultrasound stimulation in stroke: A phase I safety & feasibility trial","authors":"Ziping Huang , Charalambos C. Charalambous , Mengyue Chen , Taewon Kim , Estate Sokhadze , Allen Song , Sin-Ho Jung , Shashank Shekhar , Jody A. Feld , Xiaoning Jiang , Wuwei Feng","doi":"10.1016/j.brs.2025.01.015","DOIUrl":"10.1016/j.brs.2025.01.015","url":null,"abstract":"<div><h3>Objective</h3><div>We aimed to determine the maximum safe spatial-peak pulse-average intensity (I<sub>SPPA</sub>) of low-intensity focused ultrasound stimulation (LIFUS) in stroke patients and explore its effect on motor learning and corticospinal excitability.</div></div><div><h3>Methods</h3><div>We adopted the classic 3 + 3 design to escalate I<sub>SPPA</sub> (estimated in-vivo transcranial value) from 0, 1, 2, 4, 6, to 8 W/cm<sup>2</sup>. Stopping rules were pre-defined: 2<sup>nd</sup>-degree scalp burn, clinical seizure, new lesion on diffusion-weighted imaging or major reduction in apparent diffusion coefficient, and participant discontinuation due to any reason. We applied 12-min LIFUS over the ipsilesional motor cortex while participants were concurrently practicing 3 blocks of a motor sequence learning (MSL) task using the affected hand. We measured MSL (response time) and corticospinal excitability (motor evoked potential) pre- and post-stimulation and compared MSL and corticospinal excitability between the LOW (0, 1, and 2 W/cm<sup>2</sup>) and HIGH (4, 6, and 8 W/cm<sup>2</sup>) groups.</div></div><div><h3>Results</h3><div>I<sub>SPPA</sub> was escalated to 8 W/cm<sup>2</sup> with 18 stroke participants without meeting the stopping rules. Compared to the LOW, more participants in the HIGH performed better on MSL (6/9 vs. 0/9, <em>p</em> = 0.009) and showed a sign of greater corticospinal excitability (7/9 vs. 5/9, <em>p</em> = 0.62).</div></div><div><h3>Interpretation</h3><div>Our phase-I safety study suggests that one session of LIFUS up to 8 W/cm<sup>2</sup> I<sub>SPPA</sub> is safe and feasible in stroke patients, and LIFUS at high intensity induces positive changes in both MSL and corticospinal excitability. The next logical step is to conduct a phase-II trial testing the efficacy of LIFUS and continuously monitoring its safety profiles.</div></div>","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"18 1","pages":"Pages 179-187"},"PeriodicalIF":7.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}