BMC Women's Health最新文献

{"title":"Rural-urban disparities in cervical cancer screening uptake and its predictors among women aged 30-49 years in Ghana: a multivariate decomposition analysis.","authors":"Prince Tsekpetse, Samuel Salu, David Mensah Otoo, Joy Flora Dushime, Joshua Shiuma, Betty Oloo, Bright Opoku Ahinkorah","doi":"10.1186/s12905-025-03962-2","DOIUrl":"10.1186/s12905-025-03962-2","url":null,"abstract":"<p><strong>Background: </strong>Despite the high morbidity and mortality associated with cervical cancer in Ghana, screening uptake remains alarmingly low. Rural-urban disparities exist in screening uptake among women aged 30-49 years, a priority group for cervical cancer screening according to the World Health Organisation guidelines. This study examined rural-urban disparities in cervical cancer screening uptake and its predictors among women aged 30-49 years.</p><p><strong>Methods: </strong>We analysed secondary data from the 2022 Ghana Demographic and Health Survey, comprising 7,105 women aged 30-49 years. A multivariate non-linear decomposition analysis was conducted to examine factors explaining rural-urban disparities in cervical cancer screening uptake. Furthermore, bivariate and multivariable logistic regression analyses were performed to identify predictors of screening uptake.</p><p><strong>Results: </strong>Cervical cancer screening uptake was higher among urban women (9.66%) [n = 335/3,471; 95% CI: 8.15-11.41] than rural women (4.12%) [n = 150/3,634; 95% CI: 3.30-5.14]. Approximately 92% of the rural-urban disparity in cervical cancer screening uptake was attributable to differences in education, household wealth and media exposure. Among rural women, higher cervical cancer screening uptake was associated with older age (45-49 years; AOR = 2.11; 95% CI: 1.20-3.70), higher educational attainment (AOR = 11.78; 95% CI: 6.38-21.78), and frequent health facility visits (AOR = 2.19; 95% CI: 1.21-3.98). Among urban women, cervical cancer screening uptake was significantly associated with higher educational attainment (AOR = 3.03; 95% CI: 1.48-6.23) and being in the highest wealth index (AOR = 5.47; 95% CI: 1.34-22.33).</p><p><strong>Conclusion: </strong>Cervical cancer screening uptake remains significantly lower among rural women compared to urban women in Ghana. The rural-urban disparities in cervical cancer screening uptake were largely due to differences in socio-demographic, socio-economic and behavioural characteristics. Key predictors of cervical cancer screening uptake included older age, higher education levels, more frequent visits to health facilities, and belonging to wealthier households. These findings underscore the need for targeted interventions, such as mobile screening units, community-based education, enhanced media campaigns, and subsidising the cost of cervical cancer screening, to address access barriers and improve equitable uptake across rural and urban settings.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"396"},"PeriodicalIF":2.7,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12366028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144882197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the connection between maternal mental health and partnership, parental role, and satisfaction with various aspects of life using pairfam data: a cross-sectional analysis.","authors":"Monique Förster, Claudia Kirsch, Julia Habermann, Dorothee Noeres","doi":"10.1186/s12905-025-03933-7","DOIUrl":"10.1186/s12905-025-03933-7","url":null,"abstract":"<p><strong>Background: </strong>Decreased maternal mental health leads to difficulties for the mother herself and for her family life. In Germany, inpatient mother-/father-child preventive and rehabilitation clinics are addressing these parental health problems. Further analysis, however, is needed in order to better understand the origins of impaired parental health and to improve the interventions. The present study focuses on maternal mental health and its association with strains related to mothers' parental role, their partnership, and satisfaction with various aspects of life.</p><p><strong>Methods: </strong>For this cross-sectional study data from the relationship and family panel pairfam, wave 11, were used. Mothers in a cohabiting relationship with at least one child living in their household were examined. T-tests were employed to compare mentally stressed and mentally not stressed mothers in terms of (1) partnership (disagreements with partner, own destructive conflict behaviour, partner support and recognition), (2) parental competence, (unspecific strain, missing autonomy, and overprotectiveness in the parental role), and (3) satisfaction with work-life balance, leisure activities, friends and social contacts, and family. Multiple linear regression analysis was conducted, with the mental health composite scale of the Short Form 12 (Version 2.0) Health Survey as the dependent variable, and the previously mentioned variables as independent variables.</p><p><strong>Results: </strong>Among 1,441 mothers in partnership, 153 (10.6%) were mentally stressed. Mean comparisons indicated significantly poorer values for mentally stressed mothers across all variables. The results of the linear regression model demonstrated a correlation between maternal mental health and disagreements with the partner (B=-1.318, p =.002), own destructive conflict behaviour (B=-1.232, p =.002), parental competence (B = 1.606, p <.001), unspecific strain (B=-1.402, p <.001), missing autonomy (B=-0.732, p =.030), overprotectiveness (B=-1.015, p <.001), and satisfaction with work-life balance (B=-2.537, p =.003), and family (B = 0.432, p =.029).</p><p><strong>Conclusions: </strong>The findings of this study are consistent with the existing literature, indicating that parental role has the strongest connection with maternal stress. Additionally, novel findings have been identified, including the significant associations of partnership conflict and satisfaction with work-life balance and maternal mental health.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"395"},"PeriodicalIF":2.7,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12363032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144871555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Home birth and its associated factors among mothers aged 15-49 years in Somalia: a nationwide population-based cross-sectional study.","authors":"Sahardid Hussein Ibrahim, Zhongliang Zhou, Jiao Lu, Hilal Mohamed Nor","doi":"10.1186/s12905-025-03781-5","DOIUrl":"10.1186/s12905-025-03781-5","url":null,"abstract":"<p><strong>Background: </strong>Understanding factors associated with home births is crucial for identifying appropriate interventions for mother and child survival and attaining the Sustainable Development Goals. No national studies have explicitly examined the distribution of home birth and its contributing factors. This study aims to assess the distribution of home birth and the contributing factors among mothers of reproductive age 15-49 years in Somalia.</p><p><strong>Methods: </strong>We analyzed the data of 8,631 mothers who gave birth within five years preceding the survey and provided responses on variables studied. The data was obtained from the 2020 Somali Health and Demographic Survey. Respondents' characteristics were summarized using descriptive analysis. Chi-square tests were applied to test the association between the distribution of home birth and each predictor. Multivariate logistic regression was used to assess factors contributing to home birth. We employed the STROBE checklist for manuscript reporting.</p><p><strong>Results: </strong>The prevalence of home birth among reproductive mothers in this study was, 75.5% (95% CI: 0.74-0.76). Living in the Northeast (AOR = 1.48, 95% CI: 1.17-1.86), no level of education (AOR = 2.38, 95% CI: 1.84-3.06), no media exposure (AOR = 3.67, 95% CI: 3.25-4.13), poor household wealth status (AOR = 3.80, 95% CI: 3.07-4.71), maternal autonomy (AOR = 1.36, 95% CI: 1.21-1.53), need companionship to treatment facility (AOR = 1.20, 95% CI: 1.07-1.36), and no antenatal visits (AOR = 3.91, 95% CI: 1.66-9.26) were associated with increased likelihood of home births among mothers. By contrast, urban and rural residences, low parity, and first-trimester antenatal visits were associated with a decreased likelihood of home births among mothers of reproductive age 15-49 years in this study.</p><p><strong>Conclusion: </strong>The Somali government has made efforts to improve maternal health utilization and reduce the associated deaths. However, three-quarters of Somali mothers still undergo home births. To lower home births in Somalia, government and non-governmental organizations should consider scaling institutional births by improving maternal level of education, media accessibility, and household wealth status. Priority emphasis must be given to the maternal knowledge of the benefits of antenatal visits for both herself and her baby.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"394"},"PeriodicalIF":2.7,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12355782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144854680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polycystic ovary syndrome (PCOS) management using a nutrition recommender mobile application: identifying key requirements.","authors":"Fahimeh Solat, Sharareh Rostam Niakan Kalhori, Goli Arji, Meysam Rahmani Katigari, Jebraeil Farzi, Mobina Zeinalabedini, Leila Shahmoradi, Leila Azadbakht","doi":"10.1186/s12905-025-03936-4","DOIUrl":"10.1186/s12905-025-03936-4","url":null,"abstract":"<p><strong>Objective: </strong>Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder that affects 5-18% of women worldwide. Adopting a healthier lifestyle, especially by making nutritious dietary choices, can significantly improve the management of symptoms and reduce complications associated with this condition. Despite the growing number of mobile health (mHealth) applications, most existing tools for PCOS lack scientific validation and dietary recommendations. This study aims to identify key requirements for developing a nutritional recommender mobile application for PCOS management.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted in three stages: (1) Systematic review of articles and review of available mobile applications, (2) Data collection tool design, and (3) Validation of mobile application requirements based on the opinion of experts to provide nutritional recommendations for individuals with PCOS. (4) Design and evaluation of mobile application. Based on the results from the first stage, we created the questionnaire and assessed its validity based on the opinions of five experts in nutrition and dietetics, and health information management. Content modifications were made based on their opinions. The reliability was confirmed with a Cronbach's alpha Coefficient of 74%. The questionnaire was distributed to seven PhD candidates and eight faculty members (from the Nutrition and Dietetics Department and the Health Information Management and Medical Informatics Department), and the results were analyzed and validated via SPSS 27 via CVR calculations.</p><p><strong>Results: </strong>In the first and second stages of the study, a total of 75 items were identified across four categories: educational needs (14 items), demographic information (nine items), data elements (32 items), and mobile application features (20 items). In the third stage, 56 items were considered high priority for inclusion in the mobile application based on their content validity ratio (49%< CVR).</p><p><strong>Conclusions: </strong>Considering the importance of self-care in patients with PCOS, the integration of a nutrition recommender mobile application can significantly enhance the lifestyle of individuals with PCOS, so it is essential to identify the requirements before conceptual design and application development for app usability and increasing user satisfaction.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"393"},"PeriodicalIF":2.7,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12351836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144854681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of standardised tools to measure post-mastectomy quality of life among women in Africa: a scoping review.","authors":"Alexis Harerimana, Gugu Mchunu","doi":"10.1186/s12905-025-03858-1","DOIUrl":"10.1186/s12905-025-03858-1","url":null,"abstract":"<p><strong>Background: </strong>Breast cancer survivorship is increasingly prevalent, yet quality of life (QoL) outcomes post-mastectomy remain a critical concern in Africa. Women post-mastectomy encounter significant physical, psychological, social, and sexual health challenges that are inadequately addressed in clinical settings. Using standardised tools to measure QoL post-mastectomy of women is imperative. Thus, this scoping review aims to map evidence on the use of standardised tools to measure post-mastectomy quality of life among women in Africa.</p><p><strong>Methods: </strong>This scoping review followed the Levac et al. framework. A systematic search-between 2015 and 2025 across Africa-yielded 473 records: 345 from five databases-CINAHL (n = 22), Emcare (n = 55), Medline (n = 65), Scopus (n = 78), and Web of Science (n = 125)-and 128 from other sources. Ultimately, 34 studies met the inclusion criteria for data extraction and thematic analysis. The review followed PRISMA-ScR guidelines.</p><p><strong>Results: </strong>The 34 studies reviewed involved 5466 participants. Mean ages ranged from 38 to 57 years. QoL post-mastectomy was evaluated using standardised tools such as the EORTC QLQ-C30/BR23, WHOQOL-BREF, BREAST-Q, and FACT-B. Several studies translated and validated QoL assessment tools into local languages, notably Arabic and Yoruba, enhancing contextual relevance. Mastectomy negatively affected overall QoL, body image, psychological wellbeing, sexual functioning, and social relationships. Educational and psychosocial interventions enhanced QoL, particularly those integrating self-compassion training, physical rehabilitation, and group counselling.</p><p><strong>Conclusion: </strong>QoL post-mastectomy among women in Africa is significantly compromised; however, targeted psychosocial and rehabilitation interventions show promise in improving survivorship outcomes. Future research should emphasise culturally sensitive, multidisciplinary programs and adopt longitudinal designs to assess sustained effects on QoL.</p><p><strong>Implications for cancer survivors: </strong>This scoping review emphasises the need for comprehensive post-mastectomy care that includes physical, psychological, sexual, social and financial aspects. Culturally sensitive and accessible interventions are essential for improving the quality of life and long-term outcomes for women in Africa.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"392"},"PeriodicalIF":2.7,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12345023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144844488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating non-invariance of psychological intimate partner violence measures in the demographic and health surveys: roles of survey design and national context in 19 countries.","authors":"Kathryn M Yount, Erin R Johnson, Nadine J Kaslow, Yuk Fai Cheong","doi":"10.1186/s12905-025-03931-9","DOIUrl":"10.1186/s12905-025-03931-9","url":null,"abstract":"<p><strong>Background: </strong>One third of adult women report lifetime psychological intimate partner violence (IPV). Controlling behavior is a common dimension of psychological IPV; however, evidence is mixed on its cross-national and cross-time measurement invariance, limiting its use to monitor Sustainable Development Goal (SDG) 5.2.1, to eliminate all forms of violence against women. We explored easier-to-modify survey-design features and harder-to-modify individual-level and national-level characteristics that may account for non-invariance of these controlling-behavior items.</p><p><strong>Methods: </strong>We analyzed data on five controlling behaviors administered to 373,167 ever-partnered women 15-49 years in 19 low- or middle-income countries in which at least two national Demographic and Health Surveys were administered during 2005-2019. We performed multiple-group confirmatory factor analysis (MGCFA) to test for exact forms of invariance and alignment optimization (AO) to test for approximate invariance across 7-9 survey-design groups, defined by the number of preceding questionnaire modules (to proxy respondent burden) and weeks of interviewer training (to proxy interviewer skills). Adjustment for covariates in the MGCFA assessed whether individual- and national-level characteristics could account for any observed non-invariance across survey-design groups.</p><p><strong>Results: </strong>In MGCFA without covariates, configural invariance of the controlling-behavior items was observed across survey-design groups. Exact invariance, partial invariance (with 20% of parameter estimates freed), and approximate invariance were not observed across groups. In adjusted MGCFA, neither woman-level covariates (schooling, attitudes about IPV against women) nor national-level covariates (women's mean schooling, mean attitudes about IPV against women, gender-related legal environment) alone or combined accounted for the non-invariance of controlling-behavior items across survey-design groups.</p><p><strong>Conclusions: </strong>Comparing estimates for controlling behavior across country, time, and survey design variations warrants caution. Standardizing questionnaire length and interviewer training may improve the invariance of these items. Other characteristics, like ethnicity and language, may account for the non-invariance of controlling-behavior items across survey-design groups and should be tested. Current controlling-behavior items should be refined to enhance their comparability, and new controlling-behavior items should be identified and tested to improve the item set's content validity. Given current evidence of the high prevalence and health impacts of psychological IPV against women, advancing this research agenda is needed to monitor SDG 5.2.1.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"391"},"PeriodicalIF":2.7,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12345103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144844487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic, socioeconomic and functional health-related factors in the selection of vaginal pessaries used for the conservative treatment of pelvic organ prolapse: a retrospective study.","authors":"Orsolya Oláh, Miklós Romics, Nándor Ács, Richárd Cseh, Péter Nyirády, Attila Majoros","doi":"10.1186/s12905-025-03923-9","DOIUrl":"10.1186/s12905-025-03923-9","url":null,"abstract":"<p><strong>Background: </strong>Vaginal pessary therapy is a well-known conservative treatment of pelvic organ prolapse (POP). According to several national guidelines, pessary therapy should be used as a first-line treatment for pelvic organ prolapse. A distinction is made between pessaries that can be worn permanently or require daily control. This therapy is primarily chosen by elderly patients who are not suitable for surgery or by patients not wishing to undergo surgical treatment. The aim of our study was to investigate what demographic, socioeconomic and functional health-related factors play a role in the choice of the pessary types, and to provide healthcare professionals with guidance on recommending a pessary type to patients based on these factors.</p><p><strong>Methods: </strong>115 female patients using vaginal pessaries for POP were included in our study (group I:73 pts used a daily control \"cube\" pessary (DCP), group II.:42 pts used a long-term wear ring pessary (LTP). Data collection was performed between March 2021 and March 2022 through a personally completed questionnaire or telephone interview. The following factors were investigated: patients' age, fertility, education level, employment status, marital status, independence, hand function, vision, mobility, physical and sexual activity.</p><p><strong>Results: </strong>A significant difference was found between the DCP and LTP groups in terms of average age (44.9 vs. 75.7 years p < 0.0001), fertility (61.6 vs. 4.6% p < 0.0001), employment status (retired: 18 vs. 100% p < 0.0001), marital status (single: 8.3 vs. 44.1% p < 0.0001) and educational level (highest: 81.9 vs. 25.6% p < 0.0001). In terms of functional health-related factors, such as weakened hand function (1.4 vs. 34.9% p < 0.0001), vision impairment (19.4 vs. 58.1% p < 0.0001), reduced mobility (5.5 vs. 81.4% p < 0.0001), sexual activity ratio (87.5 vs. 0% p < 0.0001), and the level of physical activity (VAS: 9.5 vs. 6.1 p < 0.01) also significant differences were registered between the DCP and LTP groups.</p><p><strong>Conclusions: </strong>The choice of the type of vaginal pessary treatment for POP is influenced by many patient-side factors.</p><p><strong>Trial registration: </strong>The study was conducted with the approval of the Regional Institutional Scientific and Research Ethics Committee of Semmelweis University (SE RKEB 97/2022).</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"390"},"PeriodicalIF":2.7,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12344877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144844486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors influencing help-seeking behaviour among young women with experience of intimate partner violence in Nigeria.","authors":"Toyin Olanike Adaramoye, Sunday A Adedini, Kazeem Adebayo Sunmola","doi":"10.1186/s12905-025-03934-6","DOIUrl":"10.1186/s12905-025-03934-6","url":null,"abstract":"<p><strong>Background: </strong>Help-seeking has been identified as one of the most potent ways of stopping gender-based violence. However, studies have shown that poor help-seeking behaviour persists among women with experience with intimate partner violence (IPV) in Nigeria. This study examines the factors influencing help-seeking behaviour among young women with IPV experience in Nigeria. Young women within the age bracket of 15-29 years were considered because they are disproportionately affected by IPV.</p><p><strong>Methodology: </strong>This study utilised the 2018 Nigerian Demographic and Health Survey (NDHS) data. Data were analysed with descriptive statistics, chi-square tests, and logistic regression.</p><p><strong>Results: </strong>The results revealed that religion [χ² = 11.700, p < 0.05], place of residence [χ² = 8.710, p < 0.05], level of education [χ² = 14.659, p < 0.05], and ethnicity [χ² = 40.135, p < 0.05] significantly influence the help-seeking behaviour of young women with experience with IPV. Participants from the South-South region of Nigeria were 49% less likely to seek help (OR 0.49, CI 0.28-0.84, p < 0.05) compared to those from the South-West region. Additionally, participants with formal education were 35% less likely to seek help (OR 0.35, CI 0.15-0.84, p < 0.05) than those without formal education.</p><p><strong>Conclusion: </strong>The study recommends implementing culturally sensitive and region-specific interventions to address barriers that hinder uneducated women from seeking help. These findings also suggest that policies and programs should consider sociocultural factors such as region, ethnicity, and educational level.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"388"},"PeriodicalIF":2.7,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12345109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is hypertension negatively associated with memory performance in women during climacteric? A systematic review.","authors":"Arthur Polveiro da Silva, Laura Scatena Fávero, Adriano Bruno Corrêa, Mateus do Carmo Bardella, Luís Felipe Pengo Almeida Leite, Leonardo Santos Lopes da Silva, Márcio Fernando Tasinafo Júnior, Leonardo da Silva Gonçalves, Camila de Moraes","doi":"10.1186/s12905-025-03764-6","DOIUrl":"10.1186/s12905-025-03764-6","url":null,"abstract":"<p><strong>Background: </strong>The negative association between hypertension and memory performance has been a subject of broad debate in recent decades. Considering the neuroendocrine changes that occur during climacteric, this systematic review aimed to investigate whether hypertension is negatively associated with memory performance in women during climacteric.</p><p><strong>Methods: </strong>A comprehensive search was conducted in the MEDLINE, EMBASE, Web of Science, Scopus, and BVS electronic databases according to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Studies involving hypertensive, middle-aged women in the climacteric phase were included. The risk of bias and methodological quality was assessed using the Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies (NHLBI, NIH).</p><p><strong>Results: </strong>Out of 16 studies selected for the full-text reading phase, 5 were included in the systematic review. The included studies were predominantly longitudinal. Heterogeneity was observed in the sample size, and the tools for assessing memory, reproductive stage, and hypertension diagnosis. Two longitudinal studies reported a negative association between hypertension and memory performance, while one found no significant association. The cross-sectional studies reported that hypertensive participants demonstrated poorer memory performance compared to normotensive participants.</p><p><strong>Conclusions: </strong>Based on the included studies, the results suggests that hypertension is negatively associated with memory performance in climacteric women. However, due to the small number of studies and the fact that most were conducted in developed countries, these results should be interpreted with caution (PROSPERO registration number: CRD42023391668).</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"389"},"PeriodicalIF":2.7,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12344873/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, safety evidence, and determinants of medicine use during breastfeeding among women in Kampala, Uganda.","authors":"Ritah Nakijoba, Ronald Kiguba, Flavia Dhikusooka, Lilliane Namyenya, Joseph Musaazi, Lynn M Atuyambe, Catriona Waitt","doi":"10.1186/s12905-025-03939-1","DOIUrl":"10.1186/s12905-025-03939-1","url":null,"abstract":"<p><strong>Background: </strong>Breastfeeding is essential for child health and survival, yet breastfeeding mothers often require medications to manage postpartum and chronic conditions, raising concerns about potential infant safety. Limited research has been undertaken on medication practices during lactation, especially in low-resource settings like Uganda. The study aimed to investigate the prevalence of medicine use, evidence about safety, and factors that influence medicine use among breastfeeding women in Kampala, Uganda.</p><p><strong>Methods: </strong>We conducted a cross-sectional study among 294 breastfeeding women aged 18 years and older with infants aged 12 months and below, attending six healthcare clinics in Kampala between September 2023 and January 2024. Using a structured questionnaire, we collected data on medicine use and breastfeeding practices. Modified Poisson regression was used to identify factors associated with medicine use. Medication safety during breastfeeding was evaluated using Hale's Lactation Risk Category, the LactMed database, the WHO Anatomic Therapeutic Chemical (ATC) classification system, and Relative Infant Dose (RID), with RID > 10% considered high infant exposure.</p><p><strong>Results: </strong>Among 294 participants, the majority of infants were aged ≤ 6 months (202/294, 68.7%), while 92 (31.3%) were older than 6 months. A total of 168 women (57.1%) practiced exclusive breastfeeding. Medicine use in the past six months was reported by 232 women (78.9%), of whom 170 (64.4%) obtained medicines without prescriptions. Medicine use was more common among women with younger infants (adjusted prevalence ratio [aPR] = 1.4; 95% CI: 1.1-1.6), higher educational attainment (aPR = 1.3; 95% CI: 1.1-1.4), and absence of chronic illness (aPR = 1.1; 95% CI: 1.1-1.3). The most commonly used antibiotic was metronidazole, taken by 137 (46.6%) participants, with a high relative infant dose (RID) of 11-24%. This was followed by amoxicillin and ampicillin/cloxacillin, used by 112 (38.1%). Paracetamol was the most frequently used drug (74.5%). Overall, 61.0% of medicines were classified as compatible with breastfeeding, 35.4% as probably compatible, and 2.6% as possibly hazardous. Drugs requiring cautious use included frusemide, cyproheptadine, phenylpropanolamine, metronidazole, acetaminophen with caffeine, and griseofulvin due to risks such as significant infant exposure, interference with lactation, or limited safety data. By contrast, frequently used medicines such as dihydroartemisinin/piperaquine phosphate, artemether/lumefantrine, cefixime, pyrazinamide, and ethambutol were considered acceptable during breastfeeding, although formal lactation safety studies are lacking.</p><p><strong>Conclusion: </strong>The overall prevalence of medicine use among breastfeeding women was high, with frequent self-medication using over-the-counter drugs. There is urgent need for strengthened regulatory frameworks, enhanced healthcare pr","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"387"},"PeriodicalIF":2.7,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12337373/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}