BMC Women's Health最新文献

{"title":"Women's satisfaction with health extension services and its associated factors in Hawassa City, Sidama region, Southern Ethiopia.","authors":"Bargude Balta, Zufan Ayele","doi":"10.1186/s12905-025-03824-x","DOIUrl":"10.1186/s12905-025-03824-x","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"270"},"PeriodicalIF":2.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and evaluation of an intervention package to alleviate the psychological effects of premenstrual syndrome in adolescent girls.","authors":"Hannah Asadi, Hossein Ghamari Kivi, Zahra Akhavi Samarein","doi":"10.1186/s12905-025-03690-7","DOIUrl":"10.1186/s12905-025-03690-7","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to develop and evaluate the effectiveness of a therapeutic package combining Cognitive Behavioral Therapy (CBT), Narrative Therapy, and a gender-sensitive approach to reduce the psychological and emotional challenges of Premenstrual Syndrome (PMS) in adolescent girls.</p><p><strong>Methodology: </strong>Using a quasi-experimental design, 30 adolescent girls from Saqqez, Iran, were randomly assigned to an intervention group (n = 15) or a control group (n = 15). The intervention group participated in a researcher-developed group therapy program over 10 sessions, focusing on reducing rumination and pain-related catastrophic thinking. Assessments were conducted pre-test, post-test, and at follow-up using validated psychological scales. Data were analyzed using ANCOVA.</p><p><strong>Results: </strong>The intervention significantly reduced rumination and pain catastrophizing in the experimental group compared to the control group (p < 0.05). These effects were sustained at follow-up, indicating the intervention's lasting impact on improving cognitive and emotional regulation.</p><p><strong>Conclusion: </strong>The findings demonstrate that a therapeutic package integrating CBT, Narrative Therapy, and cultural sensitivity can effectively alleviate PMS-related psychological symptoms in adolescent girls. This approach holds promise for broader applications in educational and counseling settings to enhance adolescent well-being.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"271"},"PeriodicalIF":2.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12125720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in participation for young women after breast cancer diagnosis and treatment: a qualitative study.","authors":"Amy Roder McArthur, Susan Magasi, Tamara Hamlish, Cassandra A Winters, Joy Hammel","doi":"10.1186/s12905-025-03814-z","DOIUrl":"10.1186/s12905-025-03814-z","url":null,"abstract":"<p><strong>Background: </strong>Though there is increasing attention to the experiences of young breast cancer survivors, there is a need to further examine participation changes for this population after active treatment. This study aimed to examine how person-environment interactions mediate young breast cancer survivors' participation in life, focusing on features of disability within breast cancer survivorship.</p><p><strong>Methods: </strong>This qualitative study utilized a series of two semi-structured interviews to explore the experiences of nine women diagnosed with early-stage breast cancer at or below the age of forty-five. Interpretative phenomenological analysis was used to analyze interviews.</p><p><strong>Results: </strong>Three cross-case themes were identified: (1) Nothing untouched: changes in self (2), Cancer is \"not over\": the influences of social environment on survivorship, and (3) Gaps in services and supports: systems level influences on participation.</p><p><strong>Conclusions: </strong>Participants' participation changes were shaped by environmental factors, such as the complexity of healthcare system navigation. Participants pointed to a need to connect young survivors with services and supports to improve opportunities for participation in daily life following breast cancer diagnosis and treatment. This aligns with conceptualizations of disability that identify the environment as a major driver of restricted participation for disabled people. Late effects of breast cancer impact participation and should be routinely addressed as part of cancer and survivorship care. Acknowledging disability as part of breast cancer survivorship can encourage breast cancer survivors to discuss their experiences openly and to ensure they receive the supports needed to participate fully in life.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"265"},"PeriodicalIF":2.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12123836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An objective test to assess upper limb functionality in patients with breast cancer-related lymphedema: investigation of the psychometric properties of the upper limb functional test (ULIFT).","authors":"Sukriye Cansu Gultekin, Ahmet Burak Cakir, Zeynep Gulsum Guc, Faruk Recep Ozalp, Merve Keskinkilic, Tugba Yavuzsen, Didem Karadibak","doi":"10.1186/s12905-025-03829-6","DOIUrl":"10.1186/s12905-025-03829-6","url":null,"abstract":"<p><strong>Background: </strong>Although upper limb (UL) functionality was reported to be adversely affected in patients with breast cancer- related lymphedema (BCRL), there is currently no validated, objective performance-based assessment tool designed to evaluate UL function in this population. The Upper Limb Functional Test (ULIFT) was adapted from the ADL test (TGlittre), which is widely used in clinical settings and research, and was developed to assess unilateral UL functionality. Therefore, the present study aimed to evaluate the psychometric properties of the ULIFT in patients with BCRL.</p><p><strong>Methods: </strong>The study involved 36 women with unilateral BCRL and 30 healthy women controls. Intraclass correlation coefficients (ICC) were used to assess test-retest reliability. ULIFT was conducted a second time with 36 patients (100% of the total sample) over a period of 7 to 14 days for test-retest reliability analysis. The following measures were used to investigate ULIFT convergent validity: Range of motion was assessed using a universal goniometer; UL disability with the Disability of the Arm, Shoulder and Hand (DASH) questionnaire; hand grip strength with a Jamar dynamometer; and quality of life (QoL) with the Short Form 36-item Health Survey (SF-36) survey, and Upper Limb Lymphedema 27 (ULL-27). The receiver operating characteristic (ROC) curve analysis was conducted as part of the known-group validity assessment to establish a cut-off point for ULIFT in distinguishing between patients with BCRL and healthy controls.</p><p><strong>Results: </strong>The ULIFT showed excellent test-retest reliability [ICC [95%] 0.92 (0.86-0.96)], a standard error of measurement of 3.91 s, and a minimum detectable change of 10.83 s. The sensitivity of 72.2%, specificity of 73.3% and AUC of 0.773 indicate a moderate ability of ULIFT to discriminate patients with and without impairment at a cut-off of 110.125 s. Significant correlations were found between ULIFT and UL functional measures (r ≥ 0.3), indicating convergent validity.</p><p><strong>Conclusion: </strong>ULIFT is a reliable and valid objective measurement tool for assessing unilateral UL function. The cut-off time of 110.125 s may help in clinical decision-making, particularly when used in conjunction with other assessments.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"267"},"PeriodicalIF":2.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12123721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The etiology differs regards to the locations of the lesion: a clinical experience of 1350 patients with adenomyosis confirmed by postoperative pathology.","authors":"Wanqing Li, Yuting Hang, Yunyu Xu, Wen Zhang, Ye He, Wei Ye, Xinyue Hu, Zhaolian Wei","doi":"10.1186/s12905-025-03759-3","DOIUrl":"10.1186/s12905-025-03759-3","url":null,"abstract":"<p><strong>Background: </strong>Despite proposed mechanisms hypotheses, the etiology of adenomyosis remains unclear. The limited efficacy of current therapeutic approaches may stem from insufficient understanding of its pathobiological underpinnings and the pronounced heterogeneity in clinical presentation and treatment responsiveness among subtypes. This study seeks to compare clinical and sonographic profiles of adenomyosis subtypes to elucidate distinct disease mechanisms and inform subtype-specific management strategies.</p><p><strong>Methods: </strong>In this retrospective cohort of 1,350 surgically treated and pathologically confirmed adenomyosis cases (2017-2022), patients were categorized into diffuse versus focal and anterior versus posterior lesion groups according to sonographic features. Comparative analyses of demographics, symptomatology, concurrent gynecological conditions, and laboratory profiles were conducted to delineate subtype-specific patterns.</p><p><strong>Results: </strong>1074 (79.56%) had a definitive adenomyotic sonographic signs, with 329 (30.63%) focal adenomyosis and 745 (69.37%) diffuse adenomyosis. Multivariate logistic regression analysis revealed that, compared with focal adenomyosis, diffuse adenomyosis were older (OR, 1.09; 95%CI: 1.06-1.12), had more pregnancies (OR, 1.22; 95%CI: 1.11-1.33), higher BMI (OR, 1.05; 95%CI: 1.00-1.09), long course of disease (OR, 1.06; 95%CI: 1.02-1.11) and higher risk of moderate to severe dysmenorrhea (OR, 1.88; 95%CI: 1.36-2.60). Divided to the location of adenomyosis lesion indicated by sonographic, patients in the posterior wall group (n = 418) have higher risk of moderate to severe dysmenorrhea (OR, 1.88; 95% CI: 1.36-2.60), more endometriosis combination (OR, 3.24; 95%CI: 1.85-5.68) and intraoperative blood loss (OR, 1.001; 95%CI: 1.001-1.003).</p><p><strong>Conclusion: </strong>By stratifying adenomyosis into diffuse/focal and anterior/posterior subtypes, we identified distinct clinical-pathological profiles: (1) Diffuse adenomyosis was independently associated with older age, higher gravidity, and severe dysmenorrhea, suggesting a progressive phenotype driven by tissue injury mechanisms; (2) Posterior lesions exhibited a 3.24-fold risk of concurrent endometriosis and increased surgical complexity, implicating shared pathways with deep infiltrating endometriosis. These findings redefine adenomyosis as a heterogeneous disorder with subtype-specific pathophysiology, advocating for tailored therapeutic strategies.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"268"},"PeriodicalIF":2.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12123893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Public transport systems and safety of female commuters in low-and-middle-income countries: a systematic scoping review.","authors":"Gugu G Mchunu, Desmond Kuupiel, Busisiwe P Ncama, Christopher Isike, Marcel Kistan, Julian David Pillay, Sinegugu E Duma","doi":"10.1186/s12905-025-03821-0","DOIUrl":"10.1186/s12905-025-03821-0","url":null,"abstract":"<p><strong>Background: </strong>This scoping review systematically maps and summarises research evidence concerning the safety of female commuters in public transport systems across Low- and Middle-Income Countries (LMICs). Given the essential role of public transport in LMICs, particularly for women in both formal and informal sectors, understanding the safety challenges they face is crucial.</p><p><strong>Methods: </strong>We followed the Arksey and O'Malley methodological framework to structure this scoping review. The Population (Females), Concept (safety in public transport/transit), and Context (LMICs) framework guided our eligibility criteria. We searched for original research articles in PubMed, EBSCOhost (CINAHL, PsycInfo, and Health Source: Nursing/Academic Edition), SCOPUS, and Web of Science published between 2012 and 2023, and updated in February 2025. We additionally searched Google Scholar platform, and the reference list of included studies to uncover any additional relevant literature. The study selection and data extraction were performed by two reviewers using pilot-tested forms. Thematic analysis was used to organise the data into themes and a narrative summary of the findings is presented.</p><p><strong>Results: </strong>Of the total 114 articles obtained from the database searches, 26 studies published in 14 countries met the inclusion criteria. The review identified a paucity of research in this area, with an average of three relevant papers published per year. The existing literature is geographically imbalanced, with a predominant focus on South Africa, India, and Malaysia, leaving many LMICs underrepresented. Most (11 out of 26) studies employed quantitative methods, leaving a need for more diverse research methodologies. Widespread concerns, fear of assault and harassment among women commuters across various countries; underreporting of sexual harassment, prevalence of violence against women in public transport systems with its psychological, economic, health, and social consequences; and transit sexual assault were among the themes identified.</p><p><strong>Conclusion: </strong>This scoping review reveals the urgent need for further research on the safety of female commuters in LMICs, especially in underrepresented countries, to provide a more comprehensive understanding of the challenges faced by women in diverse contexts. It advocates for diversified research methods, public awareness campaigns, improved reporting mechanisms, policy reforms, infrastructure enhancements, and culturally sensitive initiatives to ensure the safety and well-being of female commuters in public transport systems across LMICs.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"264"},"PeriodicalIF":2.4,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12121230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A pilot investigation of the impact of acute mental and physical fatigue exposure on inflammatory cytokines and state fatigue level in breast cancer survivors.","authors":"Ali A Weinstein, Krish Seth, Shana Gordy, Kashaf Jabbar, Nylab Noori, Aybike Birerdinc, Ancha Baranova, Patrice Winter, Lynn H Gerber","doi":"10.1186/s12905-025-03758-4","DOIUrl":"10.1186/s12905-025-03758-4","url":null,"abstract":"<p><strong>Background: </strong>This study aims to analyze the changes in inflammatory cytokines and state fatigue after exposure to a mental or physical fatiguing activity in breast cancer survivors (BCS).</p><p><strong>Methods: </strong>A total of 46 BCS women (age: 58.9 ± 9.1) were recruited for this study and randomly assigned to one of three groups: exposure to physical fatigue (n = 16), mental fatigue (n = 15), or control (n = 15). Participants exposed to physical fatigue performed a 6-minute walk/run test. Participants exposed to mental fatigue performed a version of a dual 2-back task on a computer. Participants in the control group watched a video for 6 min. Clinically significant fatigue was defined by the FACIT-F. Analytes in serum were profiled using the Bio-Plex 200 Suspension Array System, specifically IL-1β, IL-4, IL-5, IL-6, IL-8, IL-10, eotaxin, TNF-α, TGF-β1, and VEGF.</p><p><strong>Results: </strong>Changes in inflammatory factors in response to the assigned fatigue-inducing tasks were mainly not statistically significant. The presence of clinically significant fatigue reported at baseline was, however, related to reactions to fatigue-inducing stimuli. Levels of TGF-β and eotaxin were consistently altered in reactions to fatigue-inducing tasks, particularly in those with clinical fatigue.</p><p><strong>Conclusions: </strong>Clinically significant fatigue is related to increased inflammatory reactions to mentally or physically fatiguing tasks, highlighting the consistent impact that fatigue has across various challenges of daily activities. Acute fatigue challenges, the kind that BCS would be exposed to in everyday circumstances, does increase inflammatory responses, and those with clinically significant levels of fatigue at baseline are more likely to show these effects.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"263"},"PeriodicalIF":2.4,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12121098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An evaluation of menstrual health apps' functionality, inclusiveness, and health education information.","authors":"Emma Bucher, Callie Sharkey, Abby Henderson, Briette Basaran, Sarah Meyer, Chen X Chen","doi":"10.1186/s12905-025-03812-1","DOIUrl":"10.1186/s12905-025-03812-1","url":null,"abstract":"<p><strong>Background: </strong>Menstrual health apps have become increasingly popular, providing users with a tool to monitor and learn about menstrual cycles, symptoms, and management. While previous research examined different aspects of menstrual health apps (e.g., fertility tracking), few examined menstrual health apps comprehensively to examine the menstrual health apps' functionality, inclusiveness, and health education information. The purpose of this study was to evaluate menstrual health apps' functionality, inclusiveness, and health education information.</p><p><strong>Methods: </strong>In this descriptive study, two reviewers independently searched, screened, and evaluated each app using a standardized tool. Three terms (i.e., \"period pain,\" \"period app,\" and \"menstrual cramp\") were used to search the Apple App Store. Apps were also cross-searched on the Google Play Store. We screened 60 apps. After excluding duplicates and apps that did not meet the inclusion criteria, 14 apps were evaluated on their functionality (user experience, internet and language accessibility, privacy, cycle-prediction, and symptom-tracking ability), inclusiveness (cycle lengths and regularities, fertility goals, and gender expressions and sexualities), and menstrual health education information (credibility and comprehensiveness, presence of additional health information, and information on when to seek care). We used a modified version of the Mobile App Rating Scale to score each app.</p><p><strong>Results: </strong>For functionality, half of the apps had third-party advertisements. Most (71.4%) did not require cellular connection to utilize menstrual symptom-tracking, and 71.4% shared user data with third parties. All had cycle-prediction and symptom-tracking functions. The mean number of relevant symptoms tracked was 17.5 (SD = 5.44). None of the apps used or cited validated symptom measurement tools. For inclusiveness, all apps could be tailored to cycle lengths other than 28 days, 85.7% had ovulation prediction functions, 50% had neutral or no pronouns, and 92.9% allowed users to input at least one contraceptive type. For health education information, 42.9% cited medical literature.</p><p><strong>Conclusion: </strong>This study suggests a lack of professional involvement and gender inclusivity in menstrual health app development. Healthcare professionals should educate themselves on apps' functionality, inclusiveness, and health education information before recommending apps. Additional research is needed to understand diverse users' perspectives on menstrual health apps.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"261"},"PeriodicalIF":2.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12117836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of risk factors for high-grade cervical or endometrial lesions to triage women with AGC-FN: a retrospective study.","authors":"Shuxia Xu, Tingting Jiang, Xiaodan Mao, Liangzhi Cai, Xite Lin, Yao Tong, Binhua Dong, Pengming Sun","doi":"10.1186/s12905-025-03772-6","DOIUrl":"10.1186/s12905-025-03772-6","url":null,"abstract":"<p><strong>Background: </strong>Atypical glandular cells, favor neoplastic (AGC-FN) identified in Papanicolaou (Pap) smears may be indicative of pre-malignant and malignant cervical and endometrial lesions. However, an effective strategy for triaging patients with AGC-FN remains elusive. This study aimed to analyze the relationship between AGC-FN and high-grade lesions, as well as identify specific risk factors which can optimize the currently strategy in women with AGC-FN.</p><p><strong>Methods: </strong>This retrospective utilized data from the China's Fujian Cervical Pilot Project (FCPP). A total of 211 women diagnosed with AGC-FN according to the Bethesda 2014 classification system underwent follow-up through colposcopy, biopsy, and endometrial curettage between January 2013 and July 2021. The association between high-grade lesions and clinicopathologic features were analyzed using independent sample nonparametric tests and binary logistic regression. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of different triage strategie were evaluated.</p><p><strong>Results: </strong>There were 43.60% (92/211) and 27.96% (59/211) AGC-FN women diagnosed as ≥ endometrial precancerous lesions (≥ EPL) and CIN2 + , respectively. In women with ≥ EPL, the top 3 risk factors were higher HE4, higher CA125 and older age (adjusted odds ratio [OR_adjusted]: 3.351, 2.760, 1.124, all p < 0.05, respectively). The top 3 risk factors for ≥ HISL women were HPV-16/18 infection, HPV-16/18/58/59 infection and HR-HPV infection (OR_adjusted: 50.122, 40.043, 37.011, all p < 0.01, respectively). Interestingly, the age, CA125 and HR-HPV infection showed opposite roles in AGC-FN women with ≥ EPL and ≥ HISL. When using ≥ EPL and ≥ HISL as endpoints, strategies 2 and 4 had the highest sensitivities of 97.3% and 95.3% and highest NPV of 80.0% and 97.3% by incorporating specific risk factors, respectively. Moreover, the referral rates of strategies 1, 3 and 4 were significantly lower (76.5%, 38.0% vs 62.8%, p < 0.05).</p><p><strong>Conclusion: </strong>CA125 and HR-HPV infection emerged as significant risk factors for triaging women with AGC-FN and HPV-16 and -18, HPV-58 and -59 infections should not to be overlooked. A novel triage strategy combining CA125, CA199, HE4 and HR-HPV reduced the referral rates of biopsy and curettage without altering the original sensitivity.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"260"},"PeriodicalIF":2.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12117815/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of carbohydrate quality index on menopausal symptoms and quality of life in postmenopausal women.","authors":"Emine Elibol, Sevdenur Eski, Edanur Gez, Gizem Çamdeviren","doi":"10.1186/s12905-025-03822-z","DOIUrl":"10.1186/s12905-025-03822-z","url":null,"abstract":"<p><strong>Introduction: </strong>Menopause is a natural process that often leads to physical and emotional symptoms affecting women's quality of life. Nutrition is increasingly recognized as important in managing these symptoms, with certain dietary patterns-particularly those rich in fiber and whole grains-showing potential benefits. In many regions, including parts of Asia and countries with carbohydrate-heavy diets, carbohydrate quality may significantly influence menopausal health outcomes and related chronic conditions. This study aimed to examine the relationship between carbohydrate quality index, and menopausal symptoms and quality of life in postmenopausal women.</p><p><strong>Methods: </strong>A total of 604 postmenopausal women participated. Participants completed a demographic questionnaire, the Menopause-Specific Quality of Life Questionnaire (MENQOL) (higher scores indicate poorer quality of life), and the Menopause Rating Scale (MRS) (higher scores indicate more severe symptoms). A food frequency questionnaire was used to collect dietary intake. Carbohydrate quality was assessed using the Carbohydrate Quality Index (CQI), which considers glycemic index, fiber intake, solid carbohydrate-to-total carbohydrate ratio, and whole grain consumption. Participants were divided into five quartiles based on their CQI scores. Statistical analysis was performed using SPSS 24, with Mann-Whitney U test, Kruskal-Wallis H test, ANOVA, and regression analysis controlling for socioeconomic status, body mass index, education, and menopausal status.</p><p><strong>Results: </strong>Among the participating women, 273 were aged 30-55 years, 241 were aged 56-64 years, and 90 were aged 65 years and older. The youngest group (30-55) had the highest MENQOL (19.81 ± 9.70) and MRS (44.77 ± 30.91) scores, indicating more severe symptoms. Women postmenopausal for over 3 years reported significantly lower MENQOL scores (15.74 ± 0.42) compared to those postmenopausal for less than 3 years (17.98 ± 10.84) (Z=-1.95, p < 0.05). Across CQI quartiles, women in Q5 had significantly lowest MENQOL (14.35 ± 8.77) scores (Kruskal-Wallis χ²=2.24, p < 0.05). In regression analysis, being married (β = 0.13, p < 0.05) and receiving menopausal treatment (β = 0.11, p < 0.05) were positively associated with higher CQI scores.</p><p><strong>Conclusions: </strong>Higher carbohydrate quality, is linked to fewer menopausal symptoms. Regression analysis showed that marital status and menopausal treatment were significantly associated with Carbohydrate Quality Index scores. Further research with larger samples and longitudinal studies is needed to explore the causal relationship between carbohydrate quality and menopausal outcomes.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"262"},"PeriodicalIF":2.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12117929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}