Current research in diabetes & obesity journal最新文献_第3页

Severe Diabetic Ketoacidosis in Two Children with New Onset type 1 Diabetes after SARS-CoV-2 Infection 严重急性呼吸系统综合征冠状病毒2型感染后2例新发1型糖尿病患儿的严重糖尿病酮症酸中毒

Current research in diabetes & obesity journal Pub Date : 2021-04-07 DOI: 10.19080/crdoj.2021.14.555887

C. Ponmani

{"title":"Severe Diabetic Ketoacidosis in Two Children with New Onset type 1 Diabetes after SARS-CoV-2 Infection","authors":"C. Ponmani","doi":"10.19080/crdoj.2021.14.555887","DOIUrl":"https://doi.org/10.19080/crdoj.2021.14.555887","url":null,"abstract":"Background: An increase in the incidence and the severity of diabetic ketoacidosis (DKA) in children with new onset type1 diabetes has been reported in the COVID-19 pandemic. Studies have linked this to SARS-CoV-2 although causality could not be established. Methods: We report two children with new onset type 1 diabetes and serum autoantibodies against islet cells and glutamic acid decarboxylase who developed severe DKA following infection with SARS-CoV-2. Both tested positive for COVID -19 PCR from nasopharyngeal swabs and developed symptoms of severe DKA, shock and cerebral oedema. Both children deteriorated rapidly illustrating the combined synergistic effects of the inflammatory pathways of COVID -19 and DKA. Results: Both children needed admission to intensive care. The first child had raised inflammatory and cardiac markers and was suspected to have Paediatric multisystem inflammatory syndrome temporarily associated with COVID-19 (PIMS-TS). The period of type 1 diabetes symptoms was short in the second child, she also presented with clinical and biochemical features of pancreatitis which improved with supportive management. She also presented with biochemical thyrotoxicosis at the time of diagnosis. Conclusion: Our report shows the association between infection with SARS-CoV-2 and rapid decompensation to DKA possibly accelerating the development of new-onset type 1 diabetes in genetically predisposed children. Additionally, the second child had pancreatitis illustrating that SARS-CoV-2 can affect both the endocrine and the exocrine function of the pancreas. Enhanced vigilance and earlier intervention is needed to prevent decompensation to DKA.","PeriodicalId":92021,"journal":{"name":"Current research in diabetes & obesity journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45104412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rheumatoid Arthritis Revealed by Myocardial Infarction in a Type 1 Diabetic Patient 1型糖尿病患者心肌梗死显示类风湿关节炎

Current research in diabetes & obesity journal Pub Date : 2021-04-07 DOI: 10.19080/crdoj.2021.14.555886

M. Thabet

引用次数: 0

A Methodology to Elicit Values and Strategies in Diabetes Management 一种在糖尿病管理中激发价值观和策略的方法

Current research in diabetes & obesity journal Pub Date : 2021-04-05 DOI: 10.19080/crdoj.2020.14.555855

J. Kirk

引用次数: 0

Associations between Obesity and Sleep Quality among Older Adults in a Health Center in Iran 伊朗一家健康中心老年人肥胖与睡眠质量的关系

Current research in diabetes & obesity journal Pub Date : 2021-03-10 DOI: 10.19080/crdoj.2021.14.555884

Maryam Baradaran Binazir

引用次数: 0

An Experimental Study to Evaluate Hypolipidemic Effect of Terminalia arjuna on High Fat Diet Induced Dyslipidaemia in Wistar Rat 紫苏对高脂饮食诱导的Wistar大鼠血脂异常影响的实验研究

Current research in diabetes & obesity journal Pub Date : 2021-02-22 DOI: 10.19080/crdoj.2021.14.555882

R. Nath

{"title":"An Experimental Study to Evaluate Hypolipidemic Effect of Terminalia arjuna on High Fat Diet Induced Dyslipidaemia in Wistar Rat","authors":"R. Nath","doi":"10.19080/crdoj.2021.14.555882","DOIUrl":"https://doi.org/10.19080/crdoj.2021.14.555882","url":null,"abstract":"Introduction: Hyperlipidaemia is a well-established cardiovascular disease risk factor. Different medications are used to regulate dyslipidaemia. Efficacy and safety are questionable on treatment with lipid lowering drug for long period. Need of time is to search for new lead compound from phytoconstituents of plants which is equal in potency and efficacy with present oral hypolipidemic drug but with fewer side effects. Terminalia arjuna has hypolipidemic properties therefore this research is designed to evaluate the hypolipidemic effect of Terminalia arjuna on high-fat diet induced dyslipidaemia in Wistar rats. Methods: An experimental study was done. Total 36 Wistar rats divided into 6 group randomly. Group I given normal pellet diet. In remaining group dyslipidaemia induced by high fat diet given for four weeks. Group II (dyslipidaemia control) was given high fat diet. Group III, IV were given Terminalia arjuna 250 and 500mg/kg per oral and group V, VI were given Rosuvastatin 10mg/kg and 20mg/kg per oral for 8weeks. Blood samples withdrawn by retro-orbital puncture and analysed for total cholesterol, triglycerides, HDL by commercial kits. LDL, VLDL calculated by friedewald formula. ANOVA followed by post hoc analysis used for statistical analysis. Results: Terminalia arjuna showed reduction of total cholesterol, triglycerides, VLDL, LDL level at both doses and intergroup comparison were found to be statistically significant (p<0.05) at end of treatment. The change with Terminalia arjuna(500mg/kg) in total cholesterol, triglycerides, VLDL, LDL was comparable with Rosuvastatin(10mg/kg). Conclusion: Terminalia arjuna has substantial Hypolipidemic activity as it decreases total cholesterol, triglycerides, VLDL, LDL in dyslipidaemia rat thus it has promising role in treatment of hyperlipidaemia.","PeriodicalId":92021,"journal":{"name":"Current research in diabetes & obesity journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44791719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Community-Based Interventions in the Field of Physical Activity for Rural Overweight and Obese Women in a Village In Iran 伊朗一村庄农村超重和肥胖妇女体育活动领域的社区干预

Current research in diabetes & obesity journal Pub Date : 2021-02-11 DOI: 10.19080/crdoj.2021.14.555881

Maryam Baradaran Binazir

{"title":"Community-Based Interventions in the Field of Physical Activity for Rural Overweight and Obese Women in a Village In Iran","authors":"Maryam Baradaran Binazir","doi":"10.19080/crdoj.2021.14.555881","DOIUrl":"https://doi.org/10.19080/crdoj.2021.14.555881","url":null,"abstract":"One of the most important responsibilities of governments as a social institution is the strengthening of public health of the community and the creation of the necessary places for women’s sports activities. This paper described the health effects of the Community-based interventions in the women’s park of Saeidabad village, East Azarbaijan on province, Iran. In this cross-sectional study, 109 women participated. The statistical population of the study was selected from women over 30 years in Saeidabad who were sure to experience the community-centered design of women’s park for physical activity. The participants mean age was 45.6 years. Most of them (98%) had one or more risk factor for cardiovascular disease. Thirty people were diabetic and used insulin. They lowered insulin level. Thirty-five other had hyperlipidemia whose blood lipid levels were significantly decreased. Ten people had depression. These ten stopped taking the anti-depressive pills. The Body Mass Index (BMI) of 85 of the studied people was reduced. The development of a women-specific sport area for women has been shown to have positive physical, psychological and social effects on them, where they make use of amenities in a safe and low-cost environment, and their ease of use and satisfaction from national institutions. Keywords:","PeriodicalId":92021,"journal":{"name":"Current research in diabetes & obesity journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44818721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diabetes Type II and Covid-19: Need of Rethinking II型糖尿病与新冠肺炎：需要重新思考

Current research in diabetes & obesity journal Pub Date : 2021-02-04 DOI: 10.19080/CRDOJ.2021.14.555880

Cornelli Umberto

引用次数: 1

Adiposopathy: The Role of “Sick Fat” in Cardiovascular Diseases and Exercise Mediated Improvement in Adipose Tissue Function 脂肪病:“病态脂肪”在心血管疾病和运动介导的脂肪组织功能改善中的作用

Current research in diabetes & obesity journal Pub Date : 2021-01-08 DOI: 10.19080/CRDOJ.2020.14.555879

Poonam Punjabi

{"title":"Adiposopathy: The Role of “Sick Fat” in Cardiovascular Diseases and Exercise Mediated Improvement in Adipose Tissue Function","authors":"Poonam Punjabi","doi":"10.19080/CRDOJ.2020.14.555879","DOIUrl":"https://doi.org/10.19080/CRDOJ.2020.14.555879","url":null,"abstract":"Background and aims: Positive calorie balance disrupts the function of visceral adipose tissue including cardiac and perivascular adipose tissue. Excess fat in visceral adipocytes impairs endocrine as well as immune response. The inflammatory and hormonal factors released from adipose tissue play a central role in inter-organ cross-talk. This review considers the current evidence on the role of Adiposopathy on cardiovascular disease and the importance of physical activity in restoring the function of adipocytes. Methods: Literature searches were conducted with keywords (e.g., Adiposopathy, cardiovascular disease, Exercise) using PubMed, MEDLINE, EMBASE, Science Direct, Google Scholar and DOAJ. All article types were included in the search. Results: The pathological mechanisms associated with up-regulated proinflammatory and down-regulated anti-inflammatory cytokines are responsible for the disturbed communication among muscle, liver and vasculature. In other words, Adiposopathy promote cardiovascular risk factors such as atherosclerosis, hypertension, insulin resistance, dyslipidaemia and prothrombotic state which in turn, directly and indirectly, promotes cardiovascular disease. Conclusion: of adipose tissue for the prevention and management strategies for improving cardiovascular health are suggested. a) Excess fat deposition in adipose tissue derange the internal milieu of the proinflammatory and anti-inflammatory cytokines. b) This altered milieu disturbs the normal functioning of adipocytes and interfere in the crosstalk among liver muscle and vasculature. c) The changes brought by these cytokines have profound effect on potentiating cardiovascular risk factors (CVD). d) Exercise promotes fat mobilization from adipocytes as well as rebrowning of white adipose tissue and improves CVD risk factors.","PeriodicalId":92021,"journal":{"name":"Current research in diabetes & obesity journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42739633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Personal and Family and Friends but not the Medical Team are the Sources of Support in Management of Type 2 Diabetes 个人、家人和朋友是2型糖尿病管理的支持来源，而不是医疗团队

Current research in diabetes & obesity journal Pub Date : 2020-12-22 DOI: 10.19080/CRDOJ.2020.14.555878

S. Adar

{"title":"Personal and Family and Friends but not the Medical Team are the Sources of Support in Management of Type 2 Diabetes","authors":"S. Adar","doi":"10.19080/CRDOJ.2020.14.555878","DOIUrl":"https://doi.org/10.19080/CRDOJ.2020.14.555878","url":null,"abstract":"Aim: To examine sources of support, based on the socio-ecologic model, for a better lifestyle parameter, health perceptions, and self-reported health status in people with type 2 diabetes. Methods: A telephone survey was conducted among a sample of 552 registered patients with type 2 diabetes, aged 45-70 using The-Brief-Chronic-Illness-Resources-Survey to assess sources of support to health behaviors. Logistic regression analysis adjusted for age, sex, body-mass-index, and smoking status was used. Results: No association was found between support from the medical team and health behaviors. The personal resource subscale was associated with visiting a dietitian [OR=1.3, 95%CI (1.1-1.5)], engaging in physical activity [(OR=1.3, 95%CI (1.1-1.7)], consuming a healthy diet (OR=1.6 95%CI (1.3-2.0), and having a better health perception [OR=1.31, 95%CI (1.06-1.62)]. The family and friends’ resource were associated with dietitian consultation [OR=1.3, 95%CI (1.1-1.6)] and with physical activity [OR = 2.0, 95%CI (1.6-2.6)]. Conclusion: Personal support and support of the family and friends but not medical team support subscales were the most associated with healthy diet and physical activity behaviors in people with type 2 diabetes. The medical team should emphasize the importance of lifestyle to lead changes among people with type 2 diabetes and to assess these sources of support during medical interviews.","PeriodicalId":92021,"journal":{"name":"Current research in diabetes & obesity journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41849041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of Risk Factors for Diabetes Disability Among Bangladeshi Adults 孟加拉国成年人糖尿病致残危险因素的识别

Current research in diabetes & obesity journal Pub Date : 2020-12-15 DOI: 10.19080/crdoj.2020.14.555877

Bhuyan Kc

引用次数: 0