BMC Cardiovascular Disorders最新文献

{"title":"Incidence of bleeding and performance of the PRECISE-DAPT score in predicting bleeding in patients on dual antiplatelet therapy after treatment for acute coronary syndrome in Kenya.","authors":"Peter Mugo, Mohamed Jeilan, Miriam Msunza, James Orwa, Mzee Ngunga","doi":"10.1186/s12872-024-04434-5","DOIUrl":"10.1186/s12872-024-04434-5","url":null,"abstract":"<p><strong>Introduction: </strong>Dual Antiplatelet Therapy (DAPT) plays an important role in the secondary prevention of ischemic events after treatment for acute coronary syndrome (ACS). The long-term use of DAPT is associated with an increased risk of bleeding, which affects morbidity and mortality. Risk stratification scores have been developed to predict this risk and provide a balance against the risk of ischemic events. The aim of this study was to determine the incidence of bleeding in a cohort of patients in Kenya on DAPT and assess the performance of the PRECISE-DAPT Score in predicting the risk of bleeding.</p><p><strong>Methods: </strong>This was a retrospective study conducted in three hospitals in Kenya among patients on DAPT after ACS between January 2019 and April 2022. We reviewed medical records for demographic and clinical characteristics and conducted telephone interviews to assess bleeding for patients on DAPT for a minimum period of one year. Bleeding events were categorized according to the TIMI criteria for bleeding, and the PRECISE-DAPT Score was calculated using an online calculator. The cumulative one-year incidence of bleeding was calculated and presented as frequencies and percentages. Receiver operating characteristic (ROC) analysis and C-statistics were used to quantify the ability of the PRECISE-DAPT Score to predict bleeding events, whereas calibration was estimated using the Hosmer‒Lemeshow goodness-of-fit test.</p><p><strong>Results: </strong>A total of 202 patients were enrolled in the study. The study population was predominantly male (n = 156, 77.2%) and African (n = 141, 69.8%), with a median age of 61 years (IQR 52-72). Majority were admitted with ST-Elevation Myocardial infarction (STEMI) (n = 126, 62.4%) and had a mildly reduced left ventricle ejection fraction (n = 124, 61.4%). Fourteen patients (6.9%) met the TIMI criteria for bleeding, of whom 11 (5.4%) had minimal bleeding and 3 (1.5%) had minor bleeding. There was no incidence of major bleeding. The discrimination and calibration of the PRECISE-DAPT Score was good {ROC curve 0.699 (95% CI: 0.564-0.835)} and the Hosmer-Lemeshow goodness-of-fit test (Chi-square, 6.53; p = 0.588), respectively.</p><p><strong>Conclusion: </strong>The incidence of bleeding was low, with the majority of patients having minimal bleeding that did not require medical intervention. The PRECISE-DAPT Score performed well in predicting bleeding in patients on DAPT.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"137"},"PeriodicalIF":2.0,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges faced by cardiac patients prior to coronary artery bypass grafting: a qualitative study.","authors":"Sajjad Ebrahimi, Tayebeh Hasan Tehrani, Azim Azizi, Hakimeh Vahedparast, Efat Sadeghian","doi":"10.1186/s12872-025-04577-z","DOIUrl":"10.1186/s12872-025-04577-z","url":null,"abstract":"<p><strong>Background: </strong>Coronary artery bypass grafting (CABG) is one of the most effective treatments for improving the quality of life in patients with severe coronary artery disease. However, these patients face multiple challenges prior to surgery. This study aims to elucidate the challenges faced by cardiac patients before CABG.</p><p><strong>Methods: </strong>This qualitative study used a conventional content analysis approach. Data were obtained from 26 interviews with 23 individuals, including patients and their families, physicians, and nurses from hospitals in Bushehr and Hamadan, selected through purposive sampling. Data were collected through semi-structured interviews over ten months and analyzed using MAXQDA20 software.</p><p><strong>Results: </strong>A total of 575 initial codes were extracted from the interviews and categorized into 16 subcategories based on similarities and differences. After reviewing and comparing the subcategories, five main categories of challenges faced by cardiac patients prior to coronary artery bypass surgery were identified and conceptually named. These categories included psychological and social stress during the waiting period, financial resource management for treatment, quality of information and communication, heightened need for belonging, and spirituality.</p><p><strong>Conclusions: </strong>Patients prior to coronary artery bypass grafting encounter psychological, financial, social, and spiritual challenges. A precise understanding of these challenges and the provision of psychological and social counseling to patients and their families, financial support and facilitation of treatment costs, improvement of information quality and communication between patients and the healthcare team, strengthening emotional support from family and friends, and attention to patients' spiritual needs by the healthcare team can facilitate decision-making and enhance the quality of life and surgical outcomes.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"142"},"PeriodicalIF":2.0,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869424/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between insulin resistance and QT interval: A systematic review and Meta-Analysis.","authors":"Maryam Mobasheri-Shiri, Sina Bazmi, Mohammad Saeed Soleimani-Meigoli, Zeinab Karimimoghadam, Reza Tabrizi, Mojtaba Farjam","doi":"10.1186/s12872-025-04593-z","DOIUrl":"10.1186/s12872-025-04593-z","url":null,"abstract":"<p><strong>Background: </strong>Insulin resistance (IR) is a major health concern associated with various diseases, and prolonged QT interval can potentially lead to life-threatening arrhythmias and death. There are conflicting views on the relationship between IR and QT interval. This meta-analysis aims to comprehensively investigate the association between IR and QT interval.</p><p><strong>Methods: </strong>An extensive search in databases PubMed, Scopus, Cochrane Library, Embase, and Web of Science up to October 2024 was conducted. Cohort studies which reported means and standard deviations for the QTc interval across the case and control groups with and without insulin resistance based on HOMA-IR were eligible for inclusion. Research with partial or inaccessible primary data, those involving participants with pre-existing cardiac conditions, and those with ambiguous results were excluded. The evaluation of study quality utilized the Newcastle-Ottawa Scale. A random-effects model was applied for the meta-analysis, and Egger's test was used to assess publication bias. GRADEproGDT was used to evaluate the certainty of the evidence.</p><p><strong>Results: </strong>Five studies, encompassing 603 participants, met the inclusion criteria. A significant positive association was observed between IR and QT interval (Weighted Mean Difference [WMD] = 12.38, 95% Confidence Interval [CI]: 5.51, 19.25). All included studies demonstrated high methodological quality. Assessment for publication bias revealed no significant findings (p-value for Egger's test = 0.39). The quality of evidence for the main outcome was moderate. Subgroup analyses revealed a significant link between IR and QT interval in studies from Turkey and India, with samples over fifty, and involving adults.</p><p><strong>Conclusions: </strong>This meta-analysis highlights that IR is linked to an elevated risk of QT prolongation. Early identification of IR is crucial to mitigate the risk of QT prolongation and subsequent arrhythmias, thus emphasizing the importance of early intervention to prevent adverse cardiac outcomes and sudden cardiac death. Caution is needed when interpreting our results due to study heterogeneity, certainty of evidence, and sensitivity analysis findings. More rigorous research on this subject is required.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"139"},"PeriodicalIF":2.0,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adipokine isthmin-1 is a potential predictor of abnormal urine Na⁺ excretion and insulin resistance for primary hypertension.","authors":"Chunyan Deng, Xiaoxin Zhou, Longlong Zhang, Qiuxiang You, Cong Liu, Yundong Zhang, Jian Yang","doi":"10.1186/s12872-025-04585-z","DOIUrl":"10.1186/s12872-025-04585-z","url":null,"abstract":"<p><strong>Background: </strong>Isthmin-1 (ISM1) plays an important role in maintaining glucose homeostasis and lipid metabolism. However, the relationship between circulating ISM1 and hypertension remains unclear. This study was aimed to investigate the association between serum ISM1 levels and blood pressure and evaluate value of circulating ISM1 for predicting abnormal Na⁺ excretion and insulin resistance.</p><p><strong>Methods: </strong>Four hundred sixty-eight individuals newly diagnosed with primary hypertension and 582 healthy individuals were initially screened. 84 participants were eligible for this case-control study. Serum ISM1 levels were assessed using ELISA. Spearman correlation analysis and partial correlation analysis were conducted to confirm the correlation. Multiple linear regression analysis was used to assess the independent association of serum ISM1 concentration with blood pressure. The receiver operating characteristic (ROC) curve was employed to evaluate the sensitivity of ISM1 in predicting abnormal Na⁺ excretion and insulin resistance in hypertensive subjects.</p><p><strong>Results: </strong>The serum ISM1 levels of hypertensive individuals were higher than that of healthy individuals. ISM1 levels were positively associated with systolic blood pressure (SBP), diastolic blood pressure (DBP) and brachial-ankle pulse wave velocity, but negatively associated with nocturnal urine Na⁺ concentration and excretion. These associations remained significant even after adjusting for age, body mass index, sex, heart rate, glucose, total cholesterol and estimated glomerular filtration rate. Multiple linear regression analysis revealed that SBP was an independent factor associated with serum ISM1 levels. The area under receiver operating characteristic curve (AUROC) for predicting low urine Na⁺ excretion and insulin resistance were 0.873 and 0.740, respectively.</p><p><strong>Conclusions: </strong>Serum ISM1 levels were positively associated with SBP and DBP. ISM1 may serve as a potential biomarker of abnormal urine Na⁺ excretion and insulin resistance in primary hypertensive individuals.</p><p><strong>Trial registration: </strong>Registered on chictr.org.cn 18/04/2024 (Registration number: ChiCTR2400083204).</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"136"},"PeriodicalIF":2.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between stress hyperglycemia ratio and contrast-induced nephropathy in ACS patients undergoing PCI: a retrospective cohort study from the MIMIC-IV database.","authors":"Yanlong Zhao, Yuanyuan Zhao, Shuai Wang, Zhenxing Fan, Yanling Wang, Fangyan Liu, Zhi Liu","doi":"10.1186/s12872-025-04573-3","DOIUrl":"10.1186/s12872-025-04573-3","url":null,"abstract":"<p><strong>Background: </strong>Contrast-induced nephropathy (CIN) is a significant complication in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). The role of the stress hyperglycemia ratio (SHR) as a predictor of CIN and mortality in these patients remains unclear and warrants investigation.</p><p><strong>Objective: </strong>To assess the relationship between SHR and CIN, as well as its impact on short-term mortality in ACS patients undergoing PCI.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study using the MIMIC-IV database, including 552 ACS patients. SHR was calculated as the ratio of admission glucose to estimated average glucose from hemoglobin A1c. CIN was defined as a ≥ 0.5 mg/dL or ≥ 25% increase in serum creatinine within 48 h of PCI. Logistic regression and spline models were used to analyze the association between SHR and CIN, while Kaplan-Meier curves assessed 30-day mortality.</p><p><strong>Results: </strong>Higher SHR levels were independently associated with increased CIN risk (OR 2.36, 95% CI: 1.56-3.57, P < 0.0001). A J-shaped relationship was observed, with CIN risk rising sharply when SHR exceeded 1.06. SHR was also a predictor of higher 30-day mortality (P < 0.0001). Subgroup analysis revealed a stronger SHR-CIN association in non-diabetic patients.</p><p><strong>Conclusion: </strong>SHR is an independent predictor of CIN and short-term mortality in ACS patients undergoing PCI. It offers potential for risk stratification and clinical decision-making, especially in non-diabetic patients.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"135"},"PeriodicalIF":2.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the clinical value of CCTA as the preferred screening method in patients with chronic coronary syndrome.","authors":"Huan Luo, Wei Zhu, Rui-Juan Fan, Li-Xiong Duan, Rui Jing","doi":"10.1186/s12872-025-04587-x","DOIUrl":"10.1186/s12872-025-04587-x","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;The advantages and disadvantages of direct invasive coronary angiography (ICA) and coronary computed tomographic angiography (CCTA) + ICA were compared in patients with suspected chronic coronary syndrome (CCS) who presented with angina symptoms or who had nonangina chest pain with abnormal electrocardiogram results.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A total of 1200 patients who met the inclusion criteria at TEDA International Cardiovascular Hospital from January 2021 to December 2022 were randomly divided into two groups at a 1:1 ratio: the CCTA + ICA strategy (CCTA group) and the direct ICA strategy (ICA group). The baseline data were collected. All patients in the CCTA group underwent CCTA examination first. If these results showed positive obstructive coronary artery disease (CAD), then typical angina with coronary artery stenosis ranging from 50 to 70% or vascular segments could not be analysed due to severe calcification, so ICA was further performed for definitive diagnosis, and the ICA results were taken as the final diagnosis. All patients in the ICA group underwent ICA examination directly. Demographic data, cardiovascular risk factors, biochemical criteria, chest pain classification, coronary vessel lesion severity and drug use were compared between the two groups. All patients were followed for 1 year after discharge to observe major adverse cardiovascular events (MACE). The differences in unnecessary ICA rates, 1-year MACE rates, allergic reactions to contrast agents and hospitalization costs between the two groups were analysed. On the basis of the baseline clinical data of patients included in this study, a risk prediction model for obstructive CAD was established by logistic regression.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;(1) There were 592 patients in the CCTA group and 594 patients in the ICA group. The percentage of unnecessary ICA procedures was 7.5% in the CCTA group and 55.2% in the ICA group (P &lt; 0.001), which was a decrease of 86.4%. (2) Eighteen patients in the CCTA group were readmitted for severe angina, 4 of whom underwent unplanned percutaneous coronary intervention (PCI). Eight patients in the ICA group were readmitted for severe angina, 2 of whom underwent unplanned PCI. There were no cardiac deaths, nonfatal myocardial infarctions or strokes in either group over the 1-year follow-up. There was no statistically significant difference in the rate of MACE-free survival between the two groups (97.0% vs. 98.7%, log-rankχ²=1.996, P = 0.158). (3) Allergic reactions to contrast agent were observed in 28 patients in the CCTA group and 16 in the ICA group (P = 0.190). (4) The median hospitalization cost in the CCTA group was $1259.54, and that in the ICA group was $1399.41, which was a significant difference (P &lt; 0.001) and a decrease of 9.99%. (5) Based on the combination of the logistic regression forward selection method and backward elimination method, variables with P &lt; 0.05, including creatini","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"130"},"PeriodicalIF":2.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11853221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143498267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A nomogram to predict congestive heart failure in patients with acute kidney injury: a retrospective study based on the MIMIC-III database.","authors":"Quankuan Gu, Yucheng Qi, Yaxin Xiong, Xinyue Ma, Jun Lyu, Wei Yang, Xianglin Meng, Mingyan Zhao","doi":"10.1186/s12872-025-04569-z","DOIUrl":"10.1186/s12872-025-04569-z","url":null,"abstract":"<p><strong>Object: </strong>Objective: Acute Kidney Injury (AKI) is a renal disease marked by diminished urine output and elevated serum creatinine levels. AKI has a global incidence rate of about 20%, with an average mortality rate of 23%. Cardiovascular disease emerges as one of the primary causes of death associated with AKI. We developed a nomogram to estimate the probability of patients with AKI developing congestive heart failure.</p><p><strong>Method: </strong>We conducted a retrospective study of patients with AKI, using the MIMIC-III database. The patients were randomly divided into training and validation cohorts. Variables were selected via logistic regression, followed by the construction of the nomogram. The accuracy and sensitivity of the predictive model were verified using the Hosmer-Lemeshow test (HL) and the Area Under the Curve (AUC). The nomogram and SOFA scores were compared to APSIII using the Net Reclassification Index (NRI), Integrated Discrimination Improvement (IDI), Calibration curves, and Decision Curve Analysis (DCA).</p><p><strong>Results: </strong>The final study included 9,174 individuals. The multivariate logistic regression revealed a correlation between age, Systolic Blood Pressure (SBP), Partial Pressure of Oxygen (PO2), hemoglobin, Blood Urea Nitrogen (BUN), Chloride (Cl^-), cardiac arrhythmias, valvular heart disease, pulmonary circulation disease, chronic pulmonary disease, and diabetes. These factors are strongly associated with the development of congestive heart failure. Based on these findings, we created a nomogram. This nomogram has a higher predictive effect than the SOFA score and the APSIII score (AUC = 0.751, SOFA: 0.659, APSIII: 0.62). Its verification through NRI, IDI, and DCA demonstrated that this nomogram offers superior specificity and clinical prognosis compared to the SOFA score and APSIII score.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"133"},"PeriodicalIF":2.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11853194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing cross-over stenting and focal ostial stenting for ostial left anterior descending coronary artery lesions: a systematic review and meta-analysis.","authors":"Ahmed M Khairy, Abdelrahman H Hafez, Ahmed Elshahat, Ahmed Emara, Hadeel Aboueisha, Mohamed Ismael Fahmy, Ahmed Abdelaziz, Ibrahim Yasseen","doi":"10.1186/s12872-024-04393-x","DOIUrl":"10.1186/s12872-024-04393-x","url":null,"abstract":"<p><strong>Background: </strong>The ideal revascularization approach for ostial left anterior descending coronary artery (L.A.D.) lesions continues to be a matter of debate. Two primary stenting strategies are often contemplated for managing these lesions: focal ostial stenting (F.O.S.) and the provisional strategy, alternatively termed cross-over stenting (C.O.S.) from the LM to the L.A.D. artery.</p><p><strong>Aim: </strong>Our objective is to assess the efficacy of C.O.S. vs. F.O.S. techniques in patients with ostial L.A.D. lesions who underwent percutaneous coronary intervention (P.C.I.).</p><p><strong>Methods: </strong>We systematically searched five electronic databases to identify relevant studies. The data was pooled as odds ratio (O.R.) with its 95% confidence interval (C.I.) using the DerSimonian-Laird random effect model in STATA 17 MP. Significance was determined by a p-value > 0.05 between intervention subgroups.</p><p><strong>Results: </strong>Nine articles with a total of 1492 patients were included in the meta-analysis. The pooled O.R. for Major Adverse Cardiovascular Events (MACE) was 0.88 (95% C.I. [0.39, 1.99], P = 0.76), indicating comparable rates between F.O.S. and C.O.S. For all-cause death, the O.R. was 1.46 (95% C.I. [0.53, 4.02], P = 0.46), with no significant differences between the compared techniques. Cardiovascular death showed no preference between treatments (O.R.=0.99, 95% C.I. [0.30, 3.31], P = 0.99), and similarly for myocardial infarction (O.R.=0.74, 95% C.I. [0.38, 1.44], P = 0.37).</p><p><strong>Conclusion: </strong>Our meta-analysis comparing C.O.S. and F.O.S. for L.A.D. lesions revealed similar efficacy in clinical and angiographic outcomes.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"131"},"PeriodicalIF":2.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11852548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy of ECG smart chest patches versus PPG smartwatches for atrial fibrillation detection: a systematic review and meta-analysis.","authors":"Olivier Sibomana, Clyde Moono Hakayuwa, Abraham Obianke, Hubert Gahire, Jildas Munyantore, Matimba Molly Chilala","doi":"10.1186/s12872-025-04582-2","DOIUrl":"10.1186/s12872-025-04582-2","url":null,"abstract":"<p><strong>Introduction: </strong>Atrial fibrillation (AF), the most common form of cardiac arrhythmia, is associated with significant morbidity, mortality, and financial burden. Traditional diagnostic methods, such as 12-lead electrocardiograms (ECG), have limitations in detecting intermittent AF episodes. Consequently, smart wearables have been introduced to enhance continuous AF monitoring. This systematic review and meta-analysis aimed to evaluate and compare the diagnostic accuracy of ECG smart chest patches and photoplethysmography (PPG)- based smartwatches in AF detection.</p><p><strong>Methods: </strong>From august 16-20, 2024, a comprehensive search was conducted across PubMed/MEDLINE, DOAJ, AJOL, and the Cochrane Library. Original studies assessing the performance of ECG smart chest patches and PPG smartwatches in detecting AF were included. Studies were screened based on predefined inclusion and exclusion criteria, and the most relevant were finally included. For ECG smart chest patches and PPG smartwatches groups, random-effects model was used to pool these performance metrics. Statistical analyses were performed using Jamovi 2.3.28, with a significance threshold of p < 0.05.</p><p><strong>Results: </strong>A total of 15 studies were included in the current systematic review and meta-analysis. ECG smart chest patches demonstrated a pooled sensitivity of 96.1% [(95% CI: 91.3-100.8), (I² = 94.59%)], and a pooled specificity of 97.5% [(95% CI: 94.7-100.2), (I² = 79.1%)]. PPG smartwatches showed a pooled sensitivity of 97.4% [(95% CI: 96.5-98.3), (I² = 3.16%)], and a pooled specificity of 96.6% [(95% CI: 94.9-98.3), (I² = 75.94%)]. Comparatively, both ECG smart chest patches and PPG smartwatches exhibited excellent performance in atrial fibrillation detection, with PPG smartwatches showing slightly higher sensitivity and ECG chest patches exhibiting marginally greater specificity.</p><p><strong>Conclusion: </strong>Both ECG smart chest patches and PPG smartwatches are highly effective for detecting atrial fibrillation. However, further advancements are needed to match their accuracy with that of standard diagnostic methods and achieve comprehensive digital cardiac monitoring.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"132"},"PeriodicalIF":2.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11853970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effective discrimination of wide QRS complex tachycardia with a new algorithm - the Prelocalization Series Algorithm.","authors":"Honglin Ni, Yue Huang, Xiaowei Pan, Xiaoli Zhang, Zhiyong Wan, Changlin Zhai, Haihua Pan","doi":"10.1186/s12872-025-04583-1","DOIUrl":"10.1186/s12872-025-04583-1","url":null,"abstract":"<p><strong>Background: </strong>Electrocardiogram (ECG) plays a crucial role in the correct diagnosis of wide QRS complex tachycardia (WCT). Objective To evaluate the diagnostic value of a new WCT discrimination algorithm, herein referred to as the Prelocalization Series Algorithm.</p><p><strong>Methods: </strong>A retrospective analysis of 181 ECGs from WCT patients was conducted using the Prelocalization Series Algorithm, Brugada Series Algorithm, and Vereckei Series Algorithm. Initially, the algorithms were used to differentiate between ventricular tachycardia (VT) and supraventricular tachycardia (SVT). Subsequently, the VT cases preliminarily judged were further differentiated into VT or preexcited tachycardia (PXT). The results were compared with the clinically confirmed diagnoses to observe the diagnostic value of the three algorithms.</p><p><strong>Results: </strong>The Prelocalization Series Algorithm demonstrated higher AUC values (0.90 vs. 0.73 vs. 0.69), sensitivity (0.91 vs. 0.61 vs. 0.50), and accuracy (0.90 vs. 0.71 vs. 0.65) in diagnosing VT compared to the Brugada Series Algorithm and Vereckei Series Algorithm. The Prelocalization Algorithm's single process (without differentiating between VT and PXT) also showed higher AUC values (0.79 vs. 0.67 vs. 0.63), sensitivity (0.96 vs. 0.91 vs. 0.76), specificity (0.62 vs. 0.44 vs. 0.49), and accuracy (0.82 vs. 0.72 vs. 0.65) than the Brugada Four-Step Method and aVR lead method. The accuracy of the Prelocalization Series Algorithm in diagnosing VT (0.90 vs. 0.82) was higher than its single process algorithm.With all differences being statistically significant (all P < 0.05).</p><p><strong>Conclusion: </strong>The Prelocalization Series Algorithm is an effective new algorithm for discriminating WCT and can be attempted for diagnosing VT, SVT, and PXT.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"134"},"PeriodicalIF":2.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11853332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143498252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}