{"title":"Development and validation of a nomogram prediction model for coronary heart disease in diabetic patients: a study based on the 2011-2020 NHANES database.","authors":"Mengxue Wang, Wenjing Zhang, Jiaqi Li, Yujie Luan, Xuanye Ding, Yuanhui Hu","doi":"10.1186/s12872-025-04972-6","DOIUrl":"https://doi.org/10.1186/s12872-025-04972-6","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the risk and influencing factors for coronary heart disease (CHD) in patients with diabetes (DM), and to develop and validate a nomogram prediction model, providing a basis for the early diagnosis and individualized intervention in patients with DM and CHD.</p><p><strong>Methods: </strong>This study was based on data from the National Health and Nutrition Examination Survey (NHANES). A total of 2,141 diabetic patients from 2011 to 2020 were included, randomly divided into a training set (n = 1,499) and a validation set (n = 642) at a 7:3 ratio. The least absolute shrinkage and selection operator (Lasso) regression analysis was used to screen risk factors, and a multivariate logistic regression model was developed to construct the DM-CHD nomogram prediction model. Model performance was internally validated using receiver operating characteristic (ROC) curves, calibration curves, and decision curve analysis (DCA).The Hosmer-Lemeshow Test was utilized to evaluate the overall goodness of fit of the nomogram.</p><p><strong>Results: </strong>Univariate analysis identified 15 factors as risk factors for DM-related CHD. Lasso regression further selected 7 key predictors: Age (OR 1.06, CI 1.05-1.08, P < 0.001), Gender (OR 0.47, CI 0.36-0.63, P < 0.001), Hypertension (OR 1.85, CI 1.33-2.57, P < 0.001), Weight Adjusted Waist Index (OR 1.50, CI 1.25-1.81, P < 0.001), Neutrophils (OR 1.09, CI 1.02-1.17, P = 0.009), Platelets (OR 0.99, CI 0.99-0.99, P < 0.001), and Triglycerides (OR 1.18, CI 1.08-1.30, P < 0.001). The area under the ROC curve (AUC) for the nomogram model was 0.758 (95% CI 0.728-0.789) in the training set and 0.747 (95% CI 0.699-0.796) in the validation set. Calibration curves and DCA indicated that the model exhibited satisfactory predictive performance. The model's reliability and clinical net benefit were further validated.</p><p><strong>Conclusion: </strong>The nomogram model developed in this study, based on multiple clinical indicators (Age, Gender, Hypertension, Weight Adjusted Waist Index, Neutrophils, Platelets, and Triglycerides), demonstrated adequate calibration and clinical net benefit in the validation cohort. The model demonstrates moderate but clinically useful discrimination ability, providing scientific guidance for early diagnosis and personalized interventions in patients with DM complicated by CHD, and may help reduce CHD risk in diabetic patients.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"624"},"PeriodicalIF":2.3,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hemodynamics assessment using 4D flow CMR before and after balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension: a retrospective observational study.","authors":"Kazuto Ohno, Kenichiro Suwa, Keitaro Akita, Ryota Sato, Terumori Satoh, Yuichiro Maekawa","doi":"10.1186/s12872-025-05068-x","DOIUrl":"https://doi.org/10.1186/s12872-025-05068-x","url":null,"abstract":"<p><strong>Background: </strong>The effect of balloon pulmonary angioplasty (BPA) on hemodynamics in chronic thromboembolic pulmonary hypertension (CTEPH), assessed using time-resolved three-dimensional cine phase-contrast cardiac magnetic resonance (4D flow CMR), remains unclear. Therefore, the present study aimed to investigate the hemodynamic features of the pulmonary artery (PA) before and after BPA and the diagnostic performance of 4D flow CMR-derived hemodynamics before BPA to predict the achievement of mean pulmonary artery pressure (mPAP) < 30 mmHg after BPA.</p><p><strong>Methods: </strong>Twenty-one patients with CTEPH who underwent 4D flow CMR before and after BPA were retrospectively enrolled. Regarding 4D flow CMR, the analysis included peak flow volume and velocity at the main PA and peak systolic wall shear stress (WSS).</p><p><strong>Results: </strong>Seventeen patients achieved a mPAP < 30 mmHg after BPA. Peak flow velocity at the main PA (262.8 ± 52.3 mm/s vs. 298.5 ± 68.3 mm/s, p = 0.015) and peak WSS (0.97 ± 0.26 Pa vs. 1.13 ± 0.37 Pa, p = 0.044) both increased after BPA compared to their values before BPA. Receiver operating characteristic analysis was performed to predict mPAP ≥ 30 mmHg after BPA based on peak flow velocity and peak WSS before BPA. The analysis revealed an area under the curve of 0.926 (p < 0.001) for peak flow velocity before BPA (sensitivity, 0.765; specificity, 0.750; cut-off, < 251 mm/s) and 0.971 (p < 0.001) for peak WSS before BPA (sensitivity, 0.882; specificity, 1.00; cut-off, < 0.89 Pa).</p><p><strong>Conclusions: </strong>Based on the study results, 4D flow CMR imaging showed improvement in hemodynamics after BPA. Furthermore, peak flow velocity and peak WSS were useful metrics for predicting the achievement of catheter-based BPA goal of mPAP < 30 mmHg with a better prognosis.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"621"},"PeriodicalIF":2.3,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12369117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Basma Badrawy Khalefa, Ahmed K Awad, Ahmed R Gonnah, Mazen Negmeldin Aly Yassin, Nada G Hamam, Hatem Eldeeb, Mohamed Ramadan, Ali Dway, Karim Alsalhi, Mohamed T Osman, Basel F Alqeeq, Mohammed Al-Tawil, Serge Sicouri, Massimo Baudo, Yoshiyuki Yamashita, Basel Ramlawi
{"title":"Cusp-overlap view versus three cusp coplanar view during transcatheter aortic valve replacement using self-expandable valves: a systematic review, meta-analysis and meta-regression.","authors":"Basma Badrawy Khalefa, Ahmed K Awad, Ahmed R Gonnah, Mazen Negmeldin Aly Yassin, Nada G Hamam, Hatem Eldeeb, Mohamed Ramadan, Ali Dway, Karim Alsalhi, Mohamed T Osman, Basel F Alqeeq, Mohammed Al-Tawil, Serge Sicouri, Massimo Baudo, Yoshiyuki Yamashita, Basel Ramlawi","doi":"10.1186/s12872-025-05009-8","DOIUrl":"https://doi.org/10.1186/s12872-025-05009-8","url":null,"abstract":"<p><p>Transcatheter aortic valve replacement (TAVR) is currently the treatment of choice for most patients with severe aortic stenosis. We conducted this meta-analysis to compare the outcomes of the cusp overlap technique (COT) versus the standard three-cusp technique during self-expandable valves implantation. We systematically searched PubMed, Scopus, Embase, Cochrane, and Web of Science (WOS) from inception to March 5, 2024. To estimate the effect size, dichotomous outcomes were pooled as RR, and continuous outcome was pooled as MD with their respective 95% CI. We included seventeen studies with a total of 3,129 patients in cusp-overlap technique (COT) arm and 2,818 patients in standard technique (ST) arm. The rate of 30-day mortality was borderline reduced in COT compared with ST, however, with no significant difference (RR = 0.61; 95% CI: [0.37-1.00], P = 0.05). Regarding conduction abnormalities, COT was related to lower risk of complete atrioventricular (AV) block (RR = 0.51; 95% CI: [0.37-0.69], P < 0.01), and permanent pacemaker implantation (PPM) (RR = 0.56; 95% CI: [0.46-0.70], P < 0.01). Mild to severe paravalvular leak (PVL) (RR = 1.00; 95% CI: [0.66-1.51], P = 1.00, I2 = 62%; P = 0.02) were comparable between COT and ST. Our study findings suggest that COT offers several advantages over ST, including reduced 30-day mortality, bleeding complications, and shorter procedural duration. The COT most importantly lowers the risk of conduction abnormalities, and hence the incidence PPM.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"619"},"PeriodicalIF":2.3,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12369103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heba T Mahmoud, Rocco Cordiano, David Merotto, Mattia Ludovico Dario, Fiorella Cavuto, Giuseppe Berton
{"title":"Long-term risk of stroke after acute coronary syndrome: the ABC-10* study on heart disease.","authors":"Heba T Mahmoud, Rocco Cordiano, David Merotto, Mattia Ludovico Dario, Fiorella Cavuto, Giuseppe Berton","doi":"10.1186/s12872-025-05040-9","DOIUrl":"https://doi.org/10.1186/s12872-025-05040-9","url":null,"abstract":"<p><strong>Background: </strong>Previous studies link myocardial infarction to increased stroke risk. This long-term prospective study examines stroke incidence and stroke-related mortality in acute coronary syndrome (ACS) patients, identifying risk factors and geographic disparities.</p><p><strong>Methods: </strong>We enrolled 535 ACS patients admitted to hospitals across three provinces in the Veneto region of Italy. Patients' residences were classified into three urban and three rural areas in each province. Patients were followed prospectively for 24 years or until death. Survival analysis was conducted using uni- and Multivariable Cox regression models.</p><p><strong>Results: </strong>All patients, except for three, completed the follow-up, totaling 6.151 person-years. During follow-up, 84 patients experienced a stroke, with 85% being ischemic and 15% hemorrhagic, proving fatal in 43 cases. The stroke incidence rate was 14/1.000 person-years. Older age (HR 1.84; 95% CI 1.30-2.60), atrial fibrillation (AF) (HR 2.64; 95% CI 1.49-4.67), and a higher albumin-to-creatinine ratio (ACR) tertile (HR 1.38; 95% CI 1.04-1.83) were independent predictors of overall stroke risk, while higher estimated glomerular filtration rate tertile (eGFR) (HR 0.71; 95% CI 0.53-0.95) was independent predictor a lower risk. A sub-analysis revealed older age (HR 2.67; 95% CI 1.60-4.45) and AF (HR 2.95; 95% CI 1.38-6.32) as independent predictors of fatal stroke. Unexpectedly, we observed a higher fatal stroke risk in urban areas (HR 1.89; 95% CI 1.03-3.48) and southern provinces (HR 1.71; 95% CI 1.15-2.53).</p><p><strong>Conclusion: </strong>This long-term cohort study reinforces the role of established clinical predictors (age, AF, renal function) in post-ACS stroke risk and highlights novel geographic disparities in fatal stroke outcomes. These findings support the integration of geographic and clinical risk stratification in long-term secondary prevention strategies.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"623"},"PeriodicalIF":2.3,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12369170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The methylation of TXNRD2 with chronic heart failure: the interaction effect between methylation regulation and clinical parameters-- a single center pilot study.","authors":"Rongrong Chen, Xufei Zhao, Bingqing Zhi, Rongqiang Zhang","doi":"10.1186/s12872-025-04951-x","DOIUrl":"https://doi.org/10.1186/s12872-025-04951-x","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"622"},"PeriodicalIF":2.3,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12369173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Israa Nather Ahmed, Fatimatuzzahra' Abd Aziz, Raid Dhia Hashim
{"title":"Correction: The correlation between serum vitamin D with Apo B and framingham risk score among a group of Iraqi subjects: a cross-sectional and prospective pilot study.","authors":"Israa Nather Ahmed, Fatimatuzzahra' Abd Aziz, Raid Dhia Hashim","doi":"10.1186/s12872-025-05117-5","DOIUrl":"https://doi.org/10.1186/s12872-025-05117-5","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"626"},"PeriodicalIF":2.3,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Global, regional and national burden of ischemic heart disease and its attributable risk factors from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.","authors":"Leyuan Yang, Bo Zheng, Yanjun Gong","doi":"10.1186/s12872-025-05022-x","DOIUrl":"https://doi.org/10.1186/s12872-025-05022-x","url":null,"abstract":"<p><strong>Background: </strong>Ischemic heart disease (IHD) continues to be the foremost contributor to global morbidity and mortality. This analysis aims to report an updated assessment of prevalence, deaths, and disability-adjusted life years (DALYs) due to IHD and its attributable risk factors in 204 countries and territories from 1990 to 2021, by age, sex, and socio-demographic index (SDI).</p><p><strong>Methods: </strong>This analysis used data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021. IHD was defined as acute myocardial infarction, chronic stable angina, chronic IHD, and heart failure due to IHD. Major indicators used in this study were prevalence, death and DALYs. All estimates were reported as absolute counts and age-standardized rates per 100,000 population, along with their 95% uncertainty intervals (UIs).</p><p><strong>Results: </strong>Globally, IHD accounted for 254.3 (95%UI: 221.4 to 295.5) million prevalent cases, 9.0 (95%UI: 8.3 to 9.5) million deaths and 188.4 (95%UI: 177.0 to 198.1) million DALYs in 2021. There was a noticeable decline in the global age-standardized death rate (ASDR) [-31.6% (95%UI: -34.9 to -28.3)] and age-standardized DALYs (ASRDALYs) [-28.8% (95%UI: -32.5 to -25.2)] from 1990 to 2021, with an estimated annual percentage change of -1.3 (95%CI: -1.34 to -1.26) and - 1.2 (95%CI: -1.25 to -1.16), respectively. In 2021, the global prevalence, death, and DALY rates of IHD were higher among males across all age groups, while death and DALY rates reaching a peak in the oldest group for both sexes. Regionally, we found a nonlinear but negative association between age-standardized prevalence rate (ASPR) and SDI. Nationally, similar negative associations were observed between ASRDALYs and SDI. High systolic blood pressure and high low-density lipoprotein cholesterol were the factors contributing most to the deaths and DALYs due to IHD.</p><p><strong>Conclusions: </strong>Despite declining global age-standardized death and DALYs rates of IHD, sustained multilevel prevention strategies remain essential. This requires population-wide risk factor reduction, targeted interventions for high-risk populations, and strengthened community healthcare networks to ensure accessible, guideline-based management.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"625"},"PeriodicalIF":2.3,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohey E A Eldeeb, Mohamed A Mostafa, Tarek A Nagiub, Mohammed H E Alshair, Islam E Shehata
{"title":"Comparative analysis of third-generation dual-energy CT and IVUS for in-stent restenosis detection.","authors":"Mohey E A Eldeeb, Mohamed A Mostafa, Tarek A Nagiub, Mohammed H E Alshair, Islam E Shehata","doi":"10.1186/s12872-025-04836-z","DOIUrl":"https://doi.org/10.1186/s12872-025-04836-z","url":null,"abstract":"<p><strong>Purpose: </strong>Prior studies have assessed in-stent diameter restenosis (ISDR) in coronary arteries using 64-slice multidetector computed tomography coronary angiography (MDCT-CA) compared to invasive coronary angiography (ICA), which is the gold standard. This study aimed to compare the diagnostic accuracy of monoenergetic reconstruction using third-generation dual-source dual-energy CT (DSDECT) to that of ICA reconstruction via adjunctive intravascular ultrasonography (IVUS) for evaluating the ISDR.</p><p><strong>Methods: </strong>A total of 95 patients with previously stented coronary arteries (involving 110 stents) underwent DSDECT followed by ICA and IVUS within a 24-h timeframe. The specificities, sensitivities, negative predictive values (NPVs), and positive predictive values (PPVs) of the DSDECT and ICA were compared for confirming or excluding the ISDR using in-stent area restenosis (ISAR) and a minimal luminal area (MLA) ≤ 4.0 mm<sup>2</sup> on IVUS as the reference standard.</p><p><strong>Results: </strong>Compared with IVUS, the latest DSDECT demonstrated good sensitivity (100%), specificity (92.4%), and accuracy (96.1%) in detecting the ISDR. Our study highlights a limitation in assessability for stents with diameters < 3 mm, emphasizing the importance of careful patient selection. When employing an IVUS MLA of 4.0 mm<sup>2</sup> as a reference for identifying the ISDR, no significant difference was observed between DSDECT and ICA in the identification of the ISDR. However, it is important to note that the use of absolute cut-offs, such as < 6.0 mm<sup>2</sup> in the left main or < 4.0 mm<sup>2</sup>, may not universally apply across varying ethnicities and between sexes. The interpretation of the minimal luminal area (MLA) should be considered in the context of individual patient characteristics, and caution is advised to avoid potential misleading conclusions based solely on absolute thresholds.</p><p><strong>Conclusion: </strong>In summary, when assessing stent patency, the latest DSDECT exhibits similar performance to coronary angiography and IVUS. Moreover, it offers noninvasiveness, cost-effectiveness, and ease of operation, which are advantageous characteristics. However, it is essential to consider limitations in patient eligibility, including factors such as prior cardiac devices, arrhythmias, and any degree of chronic renal insufficiency, which may impact CT imaging analysis. The 100% negative predictive value (NPV) of third-generation DSDECT reliably excludes in-stent restenosis (ISDR), potentially obviating invasive angiography in stable patients with patent stents.</p><p><strong>Trial registration: </strong>ZU-IRB#3915/13-8-2017 Registered 13 August 2017, email: IRB_123@medicine.zu.edu.eg.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"614"},"PeriodicalIF":2.3,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12366176/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating the effect of a smartphone-based self-help intervention on the quality of life of patients with acute coronary syndrome.","authors":"Faezeh Setoudeh, Zahra Molazem, Giti Setoodeh, Parvin Ghaemmaghami","doi":"10.1186/s12872-025-05060-5","DOIUrl":"https://doi.org/10.1186/s12872-025-05060-5","url":null,"abstract":"<p><strong>Purpose: </strong>Patients with acute coronary syndrome (ACS) face various challenges in the physical, psychological, social and functional domains of their lives, with adverse effects on their quality of life. The present study evaluated the effects of a smartphone-based self-help intervention on the quality of life of patients with ACS.</p><p><strong>Design: </strong>A randomized controlled trial.</p><p><strong>Methods: </strong>Sixty-four ACS patients were selected via convenience sampling and randomly assigned to one of the intervention or control groups (32 participants in each group). The participants in the intervention group received a smartphone-based self-help intervention in six sessions for three weeks. The smartphone-based self-help intervention involved six educational sessions delivered via WhatsApp, covering disease-related knowledge, emotional regulation, cognitive restructuring, sleep hygiene, resilience, and self-care practices. Patients accessed the material asynchronously and applied it to their daily routines. Data were collected before, immediately after, and three weeks after the intervention via a demographic questionnaire and the Ferrans and Powers Quality of Life Index (QLI). The collected data were analyzed in SPSS, version 22.</p><p><strong>Results: </strong>There were no statistically significant differences between the two study groups regarding the quality-of-life mean scores measured before (p = 0.92) and immediately after (p = 0.26) the intervention. Three weeks after the intervention, however, the intervention group's mean quality of life score was greater than that of the control group (p = 0.03). The results of the repeated-measures ANOVA revealed that the mean quality-of-life scores in the intervention group increased, whereas the mean quality-of-life scores in the control group remained stable.</p><p><strong>Conclusion: </strong>The results of this study indicated that a smartphone-based self-help intervention effectively improved the quality of life of patients with ACS. Nurse managers and clinical nurses can utilize these findings to increase the quality of life of patients.</p><p><strong>Trial registration: </strong>This trial was prospectively registered in the Iranian Registry of Clinical Trial (IRCT20220424054627N1) on 15 May 2022.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"615"},"PeriodicalIF":2.3,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12369270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Priyanka Boettger, Karolis Macius, Jamschid Sedighi, Henning Lemm, Kerstin Piayda, Bernhard Unsoeld, Samuel Sossalla, Omar Alhaj Omar, Martin Juenemann, Michael Buerke
{"title":"Short-duration atrial fibrillation in ischemic stroke: high risk despite subclinical burden-a prospective cohort study.","authors":"Priyanka Boettger, Karolis Macius, Jamschid Sedighi, Henning Lemm, Kerstin Piayda, Bernhard Unsoeld, Samuel Sossalla, Omar Alhaj Omar, Martin Juenemann, Michael Buerke","doi":"10.1186/s12872-025-05080-1","DOIUrl":"https://doi.org/10.1186/s12872-025-05080-1","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":"25 1","pages":"616"},"PeriodicalIF":2.3,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12369059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}