Journal of epidemiological research最新文献

Forecasting chronic diseases in Africans – Evidence from an immigrant population cohort experience 预测非洲人的慢性病——来自移民群体经验的证据

Journal of epidemiological research Pub Date : 2022-03-29 DOI: 10.5430/jer.v8n1p1

G. Rennert, H. Rennert, W. Saliba, A. Kebede, Sisay Yifru, Liat V. Rennert, Abebaw Gebeyehu

{"title":"Forecasting chronic diseases in Africans – Evidence from an immigrant population cohort experience","authors":"G. Rennert, H. Rennert, W. Saliba, A. Kebede, Sisay Yifru, Liat V. Rennert, Abebaw Gebeyehu","doi":"10.5430/jer.v8n1p1","DOIUrl":"https://doi.org/10.5430/jer.v8n1p1","url":null,"abstract":"Background: Many African countries have seen a decline in communicable diseases and infant mortality with a concomitant emergence of Western-type, resource-draining, chronic diseases in a growing mid-aged population. This poses a threat to countries with very limited resources and points to the urgent need for data to predict the impact of this emerging trend on health and economy.Methods: A cohort of 76,356 unselected immigrants to Israel, from the Gondar area in Ethiopia, was studied for patterns of non-communicable diseases emergence following their move to a Western environment. Age-specific prevalence rates of cardiovascular disease, cancer, and important risk factors (hypertension, diabetes, hyperlipidemia, BMI and smoking) were calculated by time since immigration and compared to those of 767,082 same period immigrants from the Former Soviet Union (FSU) and to the Israeli Jewish population, using the Clalit Chronic Disease Registry.Results: Prevalence rates of diabetes, hypertension, hyperlipidemia, obesity and smoking all increased significantly in every age-group among the Ethiopian immigrants. The increase started within 5 years of immigration and sometimes exceeded the rate in the local Israeli population, most notably with diabetes. Disease rates among the FSU immigrants were lower in magnitude and different in trend. Rates of malignancies changed differentially by type and etiology of disease.Conclusion: Major temporal increases of chronic diseases morbidity were documented in immigrants from semi-rural Ethiopia to a Western environment. African countries undergoing gradual Westernization need to take immediate preventive measures to tackle the emerging problem. These can involve health education measures or the use of risk reducing drugs as possible approaches.","PeriodicalId":91116,"journal":{"name":"Journal of epidemiological research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44345272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A review of mother-child and birth cohort studies in the Middle East Area 中东地区母婴及出生队列研究综述

Journal of epidemiological research Pub Date : 2021-01-07 DOI: 10.2139/ssrn.3523854

E. Fthenou, Samah Aboulsoud, V. Leventakou, A. Haddad, M. Kogevinas, E. Sadoun

{"title":"A review of mother-child and birth cohort studies in the Middle East Area","authors":"E. Fthenou, Samah Aboulsoud, V. Leventakou, A. Haddad, M. Kogevinas, E. Sadoun","doi":"10.2139/ssrn.3523854","DOIUrl":"https://doi.org/10.2139/ssrn.3523854","url":null,"abstract":"Mother-Child and Birth cohort studies offer an excellent opportunity to evaluate the effects of ’early life’ exposures providing an insight in the etiology of chronic diseases. To our knowledge, this is the first study that aims to provide a comprehensive review of these studies in the Middle East Area (MEA). Authors searched to relevant registries, the Pubmed interface, internet search tools and had personal contact with study PIs. The search revealed 117 mother-child and birth cohort studies from 9 MEA region countries (Iran, Israel, Jordan, Kuwait, Lebanon, Palestine, Saudi Arabia, United Arab Emirates and Qatar). Variability in the identified studies refers to the study design, objectives and the years of recruitment. Biological samples and data on environmental exposures were absent with the exception of limited studies (n = 44). This review revealed a sufficient number of available cohorts, however few have followed up children beyond the age of 2 years. Improved study designs focused on molecular and environmental data acquisition are required in a region that shares a set of unique characteristics in terms of landscape, climate, culture, and lifestyle. This review provides valuable information for planning future studies and set the grounds for collaborationswithin the MEA region and internationally.","PeriodicalId":91116,"journal":{"name":"Journal of epidemiological research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42354693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimicrobial resistance of Escherichiacoli and Salmonella isolated from retail broiler chicken carcasses in Zambia 从赞比亚零售肉鸡尸体中分离出的大肠杆菌和沙门氏菌的抗微生物药物耐药性

Journal of epidemiological research Pub Date : 2020-07-27 DOI: 10.21203/rs.3.rs-44168/v1

Elizabeth Muligisa Muonga, G. Mainda, Mercy Mukuma, G. Kwenda, B. Hang'ombe, F. Bumbangi, N. Phiri, Mwaba Mwansa, Musso Munyeme, J. Muma

{"title":"Antimicrobial resistance of Escherichiacoli and Salmonella isolated from retail broiler chicken carcasses in Zambia","authors":"Elizabeth Muligisa Muonga, G. Mainda, Mercy Mukuma, G. Kwenda, B. Hang'ombe, F. Bumbangi, N. Phiri, Mwaba Mwansa, Musso Munyeme, J. Muma","doi":"10.21203/rs.3.rs-44168/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-44168/v1","url":null,"abstract":"Antimicrobial resistance (AMR) of foodborne pathogens is of public health concern, especially in developing countries such as Zambia. This study was undertaken to determine the antimicrobial resistance profiles of Escherichia coli (E. coli) and Salmonella isolated from retail broiler chicken carcasses purchased from open markets and supermarkets in Zambia. A total of 189 E. coli and five Salmonella isolates were isolated. Identification and confirmation of the isolates were done using Analytical Profile Index (API 20E) (Biomerieux®) and 16S rRNA sequencing. Antimicrobial susceptibility tests (AST) were performed using the Kirby Bauer disk diffusion technique using a panel of 9 antibiotics. WHONET 2018 software was used to analyze AST results. The E. coli isolates were mostly resistant to tetracycline (79.4%), ampicillin (51.9%), and trimethoprim/sulfamethoxazole (49.7%). Two of the five Salmonella isolates were resistant to at least one antibiotic. This study has demonstrated the presence of AMR E. coli and Salmonella on retail broiler chicken carcasses from open markets and supermarkets, which is of public health concern.","PeriodicalId":91116,"journal":{"name":"Journal of epidemiological research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43552355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Seroprevalence of human Brucellosis and associated risk factors among high-risk occupations in Mbeya Region of Tanzania 坦桑尼亚姆贝亚地区高危职业人群布鲁氏菌病血清流行率及相关危险因素

Journal of epidemiological research Pub Date : 2020-06-03 DOI: 10.5430/jer.v6n1p1

Frederick D. Sagamiko, R. Mfune, B. Hang'ombe, E. Karimuribo, A. Mwanza, C. Sindato, J. Muma

{"title":"Seroprevalence of human Brucellosis and associated risk factors among high-risk occupations in Mbeya Region of Tanzania","authors":"Frederick D. Sagamiko, R. Mfune, B. Hang'ombe, E. Karimuribo, A. Mwanza, C. Sindato, J. Muma","doi":"10.5430/jer.v6n1p1","DOIUrl":"https://doi.org/10.5430/jer.v6n1p1","url":null,"abstract":"Background: Brucellosis is a bacterial zoonotic disease of public health and economic importance. A cross-sectional study was conducted in Mbeya region between November 2015 and January 2016 to investigate the seroprevalence of human brucellosis and identify associated risk factors among individuals in risky occupations. Methods: A total of 425 humans from six occupational categories were serially tested for Brucella antibodies using the Rose Bengal Plate Test (RBPT) and competitive Enzyme Linked Immunosorbent Assay (c-ELISA), for screening and confirmation, respectively. A questionnaire survey was also administered to participants to collect epidemiological data. Results: The overall seroprevalence among the occupationally exposed individuals was 1.41% (95% CI: 00.64-3.12). Seroprevalence was higher among butcher men 5.6% (95% CI: 1.68-5.26), herds men 1.35% (95% CI: 0.18-9.02); and abattoir workers 1.1% (95% CI: 0.26-4.22) although there was no statistical significance. (P value = .18). Seroprevalence was also higher among men (1.8%) compared to females (0%) (P value = .19). and also, among those aged < 11 years (2.5%). Individuals who consumed raw milk had a higher seroprevalence (1.56%) compared to those who drunk boiled milk while seropositivity was 0.88% among those who assisted animals during parturition (P value = .49). Butcher men were at higher risk of exposure compared to other occupational categories. Our findings show the presence of brucellosis in occupationally exposed individuals in Mbeya region.Conclusion: There is need to sensitize the concerned professions in order to reduce the risk of acquiring Brucella infections from animals and animal products This also calls for public health awareness about the disease, and implementation of measures to prevent further spread of brucellosis within and outside the study area.","PeriodicalId":91116,"journal":{"name":"Journal of epidemiological research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/jer.v6n1p1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46579596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

The effect of maternal health conditions on maternal morbidity in women with a prior cesarean: the role of elective repeat cesarean delivery 产妇健康状况对既往剖宫产妇女产妇发病率的影响：选择性重复剖宫产的作用

Journal of epidemiological research Pub Date : 2019-10-29 DOI: 10.5430/jer.v5n2p17

M. Fridman, L. Korst, Elizabeth S. Lawton, N. Greene, Samia Saeb, Lisa A. Nicholas, K. Gregory

{"title":"The effect of maternal health conditions on maternal morbidity in women with a prior cesarean: the role of elective repeat cesarean delivery","authors":"M. Fridman, L. Korst, Elizabeth S. Lawton, N. Greene, Samia Saeb, Lisa A. Nicholas, K. Gregory","doi":"10.5430/jer.v5n2p17","DOIUrl":"https://doi.org/10.5430/jer.v5n2p17","url":null,"abstract":"Background: We evaluated women with a prior cesarean delivery (CD) who were eligible for elective repeat CD or trial of labor to test whether the risk of severe maternal morbidity (SMM) was: 1) directly associated with important pre-existing and gestational conditions or 2) indirectly associated (significantly increased or decreased) with the decision to undergo elective repeat CD.Methods: Women with a prior CD who had inborn, liveborn, term, singleton, vertex deliveries were identified in California 2010-2011 hospital discharge datasets. Using discharge codes, this population was stratified into two groups: attempted labor and elective repeat CD. A mediation model (stratified by younger vs. older women [>35 years]) was built for each of the following maternal conditions (exposure): chronic/gestational diabetes mellitus (DM), chronic/gestational hypertension, heart disease, obesity, and mental health diagnoses. Elective repeat CD was the mediator and SMM was the outcome.Results: Of 141,535 eligible deliveries, 72.7% had an elective repeat CD; 2.3% had SMM, which occurred in 2.2% of younger vs. 2.6% of older women. For younger and older women respectively, the modeled total effect odds ratios (95% CI) for heart disease were: 10.7 (8.5, 13.5) and 8.8 (6.4, 12.2); for hypertension: 1.7 (1.4, 1.9) and 2.0 (1.6, 2.4); and for mental health diagnoses: 1.9 (1.6, 2.3) and 1.7 (1.3, 2.3). Neither DM nor obesity demonstrated a direct effect. Odds ratios for indirect effects were negligible for all models.Conclusion: Among women with a prior CD, in the presence of important health conditions, the increased risk of SMM mediated by an elective repeat CD was negligible.","PeriodicalId":91116,"journal":{"name":"Journal of epidemiological research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45977604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiological characteristics and morbidity of Snake-bites in Zunyi city, China 遵义市蛇咬伤流行病学特征及发病情况

Journal of epidemiological research Pub Date : 2019-09-17 DOI: 10.5430/jer.v5n2p11

Haiyan Wang, Haizhen Duan, Ming Qin, Yinjie Yang, Xiuquan Shi

{"title":"Epidemiological characteristics and morbidity of Snake-bites in Zunyi city, China","authors":"Haiyan Wang, Haizhen Duan, Ming Qin, Yinjie Yang, Xiuquan Shi","doi":"10.5430/jer.v5n2p11","DOIUrl":"https://doi.org/10.5430/jer.v5n2p11","url":null,"abstract":"Objectives: To investigate the epidemiological characteristics and morbidity of the snake-bite injury in Zunyi city, China, so as to provide the first aid guidance and public education for the prevention and treatment strategies of snake-bite injuries.Methods: A cross-sectional study was conducted, and 548 cases of snake-bite were observed in this study between January1, 2015 to December 31, 2017. They were identified form the Emergency Department of the Affiliated Hospital of Zunyi Medical University. A retrospective epidemiological survey was conducted to collect their information on sex, age, occupation, bite location, bite year and season, specific bite cause.Results: The number of the patients of snake-bite was increased; however, the fatality rate gradually was decreased year by year during the investigating period. Seven patients died during year 2015-2017 and the 3-year total mortality was 2.9%. Among the dead, 59.31% were male and 40.69% were female. 19.70% of patients were between 41 and 50 years old, 17.70% were between 51 and 60 years and 16.79% of patients were between 61 and 70 years old. Moreover, 66.97% of patients were on the lower extremity and 31.93% of patients on the upper extremity. 83.39% of patients were bitten while farming and 12.04% of patients were bitten while walking. Most cases occurred during summer and autumn (7-9 months) seasons. The regional distributions of 548 snake-bites were 44.34% in the County and 33.94% in districts of Zunyi city.Conclusion: Target preventive measures should be conducted in high risk populations in Zunyi city, especially in spring and summer.","PeriodicalId":91116,"journal":{"name":"Journal of epidemiological research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/jer.v5n2p11","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44765265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Absence of paramyxovirus RNA in non-human primate sanctuaries and a primatology center in Gabon 在加蓬的非人灵长类动物保护区和灵长类动物学中心未发现副粘病毒RNA

Journal of epidemiological research Pub Date : 2019-06-12 DOI: 10.5430/JER.V5N2P6

B. Ngoubangoye, G. Maganga, Larson Boundenga, Thierry Tsoumbou, V. Rougeron, I. Mombo, N. Moukodoum, D. Fouchet, F. Prugnolle, F. Renaud, D. Pontier

{"title":"Absence of paramyxovirus RNA in non-human primate sanctuaries and a primatology center in Gabon","authors":"B. Ngoubangoye, G. Maganga, Larson Boundenga, Thierry Tsoumbou, V. Rougeron, I. Mombo, N. Moukodoum, D. Fouchet, F. Prugnolle, F. Renaud, D. Pontier","doi":"10.5430/JER.V5N2P6","DOIUrl":"https://doi.org/10.5430/JER.V5N2P6","url":null,"abstract":"The viruses of the Paramyxoviridae family are known to infect a wide range of animals, including primates, birds, rodents,carnivores, bats, ungulates, snakes, cetaceans and humans. This study aims to investigate the circulation of paramyxoviruses in five potential host species groups (humans, non-human primates, rodents, shrews, and bats) living in the same environments in three conservation programs dedicated to non-human primates, namely the Lékédi park, the primatology center of the International Center for Medical Research of Franceville and the Gorilla Protection Program, located in Gabon. We tested 35 workers, 343 NHPs (8 species), 141 bats (4 species), 420 rodents (5 species) and 10 shrews, sampled between 2013 and 2014. Faecal and organ samples were analyzed using three heminested reverse transcription-PCR (hnRT-PCR). All the 1884 samples tested were negative for PV detection. Further studies spanning a greater period of time are needed to investigate PV circulation patterns in theseconservation programs.","PeriodicalId":91116,"journal":{"name":"Journal of epidemiological research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/JER.V5N2P6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43700201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Awareness and source of AIDS-related prevention knowledge among medical university students of Guizhou province, China 贵州省医科大学生艾滋病相关预防知识知晓情况及来源

Journal of epidemiological research Pub Date : 2019-04-09 DOI: 10.5430/JER.V5N2P1

Yanna Zhou, Wanjin Yang, Xue Wang, Haiyan Wang, Deyu Zhu, Xiuquan Shi

{"title":"Awareness and source of AIDS-related prevention knowledge among medical university students of Guizhou province, China","authors":"Yanna Zhou, Wanjin Yang, Xue Wang, Haiyan Wang, Deyu Zhu, Xiuquan Shi","doi":"10.5430/JER.V5N2P1","DOIUrl":"https://doi.org/10.5430/JER.V5N2P1","url":null,"abstract":"Objective: To clarify the awareness and source of AIDS knowledge among college students of medical university of Guizhou province, China, so as to provide some basic evidences for implementing education of AIDS control and prevention .Methods: A stratified cluster sampling survey was conducted. Self-designed questionnaires were used to investigate university students, Epidata 3.0 and SPSS 8.0 were used to analyze data.Results: The awareness rate of AIDS through blood transmission and mother-to-child transmission was over 90%, the awareness rate of sexual transmission was just about 80%, and the awareness rate of non- transmission route “mosquito bites will not spread AIDS” was only 53.3%. The awareness rate of AIDS transmission and treatment among medical students was higher than that of non-medical students. The Internet, propaganda materials, newspapers and magazines, and school classes were the main ways for university students to acquire AIDS knowledge. Some students hope to acquire knowledge from classmates and friends, it was found that the proportion of medical students receiving AIDS knowledge from school classes was significantly higher than that of non-medical students (80.8% vs 73.1%, p = .007).Conclusion: Though the awareness rate of AIDS knowledge among medical students is better than that of non-medical students, they had incomplete knowledge of AIDS, especially the sexual transmission. Moreover, school classes may be an effective way to propagandize AIDS-related knowledge, so schools can consider publicizing the AIDS education through classes, so as to improve students’ abilities of AIDS control and prevention. ","PeriodicalId":91116,"journal":{"name":"Journal of epidemiological research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/JER.V5N2P1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42023921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Social activities and subjective well-being among older persons in Japan 日本老年人的社会活动与主观幸福感

Journal of epidemiological research Pub Date : 2019-03-18 DOI: 10.5430/JER.V5N1P56

Hirotaka Nakamura, C. Murata, Y. Yamazaki

{"title":"Social activities and subjective well-being among older persons in Japan","authors":"Hirotaka Nakamura, C. Murata, Y. Yamazaki","doi":"10.5430/JER.V5N1P56","DOIUrl":"https://doi.org/10.5430/JER.V5N1P56","url":null,"abstract":"Objectives: In today’s aging societies, subjective well-being is an important determinant of quality of life among older persons. The association between better health and better subjective well-being is well known. However, the kinds of social activities associated with subjective well-being are largely unknown. This study aimed to assess such relationships, taking into account the type of social activities involved among community living older persons aged 65 and over.Method: We used self-administered questionnaire data (N = 2,652) from the Japan Gerontological Evaluation Project (JAGES) 2016. We conducted a poisson regression analyses stratified by age group to elucidate the association between social activities and better subjective well-being.Results: After adjusting for sex, family composition, household income, number of illnesses and depression, we found that activities to teach skills or passing on experiences to others were significantly related to higher subjective well-being both among the young-old (65-74) and the old-old (75 and over) population.Conclusion: Altruistic activities such as teaching skills or conveying knowledge to others appear to be related to higher subjective well-being. Promoting social activities has the potential to enhance subjective well-being among the elderly population.","PeriodicalId":91116,"journal":{"name":"Journal of epidemiological research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/JER.V5N1P56","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47945876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

First outbreak of Clostridium difficile infections in Serbia: An experience of the department for orthopedic surgery 塞尔维亚首次爆发艰难梭菌感染：骨科经验

Journal of epidemiological research Pub Date : 2019-03-07 DOI: 10.5430/JER.V5N1P50

B. Mijovic, L. Marković-Denić, Dušica Banković-Lazarević, M. Račić

{"title":"First outbreak of Clostridium difficile infections in Serbia: An experience of the department for orthopedic surgery","authors":"B. Mijovic, L. Marković-Denić, Dušica Banković-Lazarević, M. Račić","doi":"10.5430/JER.V5N1P50","DOIUrl":"https://doi.org/10.5430/JER.V5N1P50","url":null,"abstract":"Objectives: Increased C. difficile infection rates were observed during the last decade, as well as the onset of complicated forms of the disease. The primary objective of this study was to report the first outbreak of C. difficile in a Serbian hospital, aiming to determine clinical and environmental factors associated with the outbreak. The secondary objective was to describe outbreak control measures taken.Design: The retrospective cohort study conducted from 18 April to 22 May 2013 in Serbian healthcare. Ninety-five patients hospitalized at the Department for orthopedic surgery during the CDI outbreak.Results: Prophylactic antibiotic therapy was identified among 93.3% patients with and 87.9% without C. difficile infection. The multivariate logistic regression analysis has shown that the independent risk factors for C. difficile infection incidence are the age beyond 70 (OR = 4.5; 95%CI = 1.1-18.2; p = .031) and the length of antibiotic therapy (OR = 1.5; 95%CI = 1.1-2.1; p = .017).Conclusion: The length of antibiotic prophylaxis is linked with the incidence. Orthopedic departments have a risk of C. difficileinfection. Infection control measure, antimicrobial stewardship programs and compliance to guidelines for the prescribing of antibiotics play important role in the prevention of C. difficile infection burden.","PeriodicalId":91116,"journal":{"name":"Journal of epidemiological research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/JER.V5N1P50","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48346375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0