Biophysical reviews最新文献_第8页

Diversity and features of proteins with structural repeats. 具有结构重复的蛋白质的多样性及其特征

IF 4.9

Biophysical reviews Pub Date : 2023-09-07 eCollection Date: 2023-10-01 DOI: 10.1007/s12551-023-01130-0

Evgeniya I Deryusheva, Andrey V Machulin, Oxana V Galzitskaya

引用次数: 0

Terahertz spectroscopy as a method for investigation of hydration shells of biomolecules. 太赫兹光谱作为研究生物分子水合壳的一种方法

IF 4.9

Biophysical reviews Pub Date : 2023-09-07 eCollection Date: 2023-10-01 DOI: 10.1007/s12551-023-01131-z

Nikita V Penkov

{"title":"Terahertz spectroscopy as a method for investigation of hydration shells of biomolecules.","authors":"Nikita V Penkov","doi":"10.1007/s12551-023-01131-z","DOIUrl":"10.1007/s12551-023-01131-z","url":null,"abstract":"The hydration of biomolecules is one of the fundamental processes underlying the construction of living matter. The formation of the native conformation of most biomolecules is possible only in an aqueous environment. At the same time, not only water affects the structure of biomolecules, but also biomolecules affect the structure of water, forming hydration shells. However, the study of the structure of biomolecules is given much more attention than their hydration shells. A real breakthrough in the study of hydration occurred with the development of the THz spectroscopy method, which showed that the hydration shell of biomolecules is not limited to 1-2 layers of strongly bound water, but also includes more distant areas of hydration with altered molecular dynamics. This review examines the fundamental features of the THz frequency range as a source of information about the structural and dynamic characteristics of water that change during hydration. The applied approaches to the study of hydration shells of biomolecules based on THz spectroscopy are described. The data on the hydration of biomolecules of all main types obtained from the beginning of the application of THz spectroscopy to the present are summarized. The emphasis is placed on the possible participation of extended hydration shells in the realization of the biological functions of biomolecules and at the same time on the insufficient knowledge of their structural and dynamic characteristics.","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47929712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative measurement of influenza virus transmission in animal model: an overview of current state. 流感病毒在动物模型中传播的定量测量:现状概述

IF 4.9

Biophysical reviews Pub Date : 2023-09-07 eCollection Date: 2023-10-01 DOI: 10.1007/s12551-023-01113-1

Galina Onkhonova, Andrei Gudymo, Maksim Kosenko, Vasiliy Marchenko, Alexander Ryzhikov

{"title":"Quantitative measurement of influenza virus transmission in animal model: an overview of current state.","authors":"Galina Onkhonova, Andrei Gudymo, Maksim Kosenko, Vasiliy Marchenko, Alexander Ryzhikov","doi":"10.1007/s12551-023-01113-1","DOIUrl":"10.1007/s12551-023-01113-1","url":null,"abstract":"Influenza virus transmission is a crucial factor in understanding the spread of the virus within populations and developing effective control strategies. Studying the transmission patterns of influenza virus allows for better risk assessment and prediction of disease outbreaks. By monitoring the spread of the virus and identifying high-risk populations and geographic areas, it is possible to allocate resources more effectively, implement timely interventions, and provide targeted healthcare interventions to diminish the burden of influenza virus on vulnerable populations. Theoretical models of virus transmission are used to study and simulate of influenza virus spread within populations. These models aim to capture the complex dynamics of transmission, including factors such as population size, contact patterns, infectiousness, and susceptibility. Animal models serve as valuable tools for studying the dynamics of influenza virus transmission. This article presents a brief overview of existing research on the qualitative and quantitative study of influenza virus transmission in animal models. We discuss the methodologies employed, key insights gained from these studies, and their relevance.","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46101510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modeling transient ischemic attack via photothrombosis. 通过光血栓形成模拟短暂性脑缺血发作

IF 4.9

Biophysical reviews Pub Date : 2023-09-04 eCollection Date: 2023-10-01 DOI: 10.1007/s12551-023-01121-1

Y N Kalyuzhnaya, A M Khaitin, S V Demyanenko

{"title":"Modeling transient ischemic attack via photothrombosis.","authors":"Y N Kalyuzhnaya, A M Khaitin, S V Demyanenko","doi":"10.1007/s12551-023-01121-1","DOIUrl":"10.1007/s12551-023-01121-1","url":null,"abstract":"The health significance of transient ischemic attacks (TIAs) is largely underestimated. Often, TIAs are not given significant importance, and in vain, because TIAs are a predictor of the development of serious cardiovascular diseases and even death. Because of this, and because of the difficulty in diagnosing the disease, TIAs and related microinfarcts are poorly investigated. Photothrombotic models of stroke and TIA allow reproducing the occlusion of small brain vessels, even single ones. When dosing the concentration of photosensitizer, intensity and irradiation time, it is possible to achieve occlusion of well-defined small vessels with high reproducibility, and with the help of modern methods of blood flow assessment it is possible to achieve spontaneous restoration of blood flow without vessel rupture. In this review, we discuss the features of microinfarcts and the contemporary experimental approaches used to model TIA and microinfarcts, with an emphasis on models using the principle of photothrombosis of brain vessels. We review modern techniques for in vivo detection of blood flow in small brain vessels, as well as biomarkers of microinfarcts.","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41802343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Towards the synthesis of spectral imaging and machine learning-based approaches for non-invasive phenotyping of plants. 基于光谱成像和机器学习的植物非侵入性表型综合方法

IF 4.9

Biophysical reviews Pub Date : 2023-09-04 eCollection Date: 2023-10-01 DOI: 10.1007/s12551-023-01125-x

Alexei Solovchenko, Boris Shurygin, Dmitry A Nesterov, Dmitry V Sorokin

引用次数: 0

Reversible protein phosphorylation in higher plants: focus on state transitions. 高等植物中可逆的蛋白质磷酸化：关注状态转换

IF 4.9

Biophysical reviews Pub Date : 2023-08-29 eCollection Date: 2023-10-01 DOI: 10.1007/s12551-023-01116-y

D V Vetoshkina, M M Borisova-Mubarakshina

{"title":"Reversible protein phosphorylation in higher plants: focus on state transitions.","authors":"D V Vetoshkina, M M Borisova-Mubarakshina","doi":"10.1007/s12551-023-01116-y","DOIUrl":"10.1007/s12551-023-01116-y","url":null,"abstract":"Reversible protein phosphorylation is one of the comprehensive mechanisms of cell metabolism regulation in eukaryotic organisms. The review describes the impact of the reversible protein phosphorylation on the regulation of growth and development as well as in adaptation pathways and signaling network in higher plant cells. The main part of the review is devoted to the role of the reversible phosphorylation of light-harvesting proteins of photosystem II and the state transition process in fine-tuning the photosynthetic activity of chloroplasts. A separate section of the review is dedicated to comparing the mechanisms and functional significance of state transitions in higher plants, algae, and cyanobacteria that allows the evolution aspects of state transitions meaning in various organisms to be discussed. Environmental factors affecting the state transitions are also considered. Additionally, we gain insight into the possible influence of STN7-dependent phosphorylation of the target proteins on the global network of reversible protein phosphorylation in plant cells as well as into the probable effect of the STN7 kinase inhibition on long-term acclimation pathways in higher plants.","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48576734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biophysical Reviews (ISSUE 4 2023): LAFeBS-highlighting biophysics in Latin America. 生物物理评论》（第 4 2023 期）：LAFeBS--突出拉丁美洲的生物物理学。

IF 4.9

Biophysical reviews Pub Date : 2023-08-29 eCollection Date: 2023-08-01 DOI: 10.1007/s12551-023-01117-x

R Daniel Peluffo, Silvia Del V Alonso, Rosangela Itri, F Luis González Flecha, Leandro Barbosa

引用次数: 0

A review of acoustofluidic separation of bioparticles. 生物颗粒声流分离研究进展

Biophysical reviews Pub Date : 2023-08-29 eCollection Date: 2023-12-01 DOI: 10.1007/s12551-023-01112-2

Fria Hossein, Panagiota Angeli

引用次数: 0

Atomic force microscopy-based approaches for single-molecule investigation of nucleic acid-protein complexes. 基于原子力显微镜的核酸-蛋白复合物单分子研究方法

IF 4.9

Biophysical reviews Pub Date : 2023-08-26 eCollection Date: 2023-10-01 DOI: 10.1007/s12551-023-01111-3

Evgeniy V Dubrovin

{"title":"Atomic force microscopy-based approaches for single-molecule investigation of nucleic acid-protein complexes.","authors":"Evgeniy V Dubrovin","doi":"10.1007/s12551-023-01111-3","DOIUrl":"10.1007/s12551-023-01111-3","url":null,"abstract":"The interaction of nucleic acids with proteins plays an important role in many fundamental biological processes in living cells, including replication, transcription, and translation. Therefore, understanding nucleic acid-protein interaction is of high relevance in many areas of biology, medicine and technology. During almost four decades of its existence atomic force microscopy (AFM) accumulated a significant experience in investigation of biological molecules at a single-molecule level. AFM has become a powerful tool of molecular biology and biophysics providing unique information about properties, structure, and functioning of biomolecules. Despite a great variety of nucleic acid-protein systems under AFM investigations, there are a number of typical approaches for such studies. This review is devoted to the analysis of the typical AFM-based approaches of investigation of DNA (RNA)-protein complexes with a major focus on transcription studies. The basic strategies of AFM analysis of nucleic acid-protein complexes including investigation of the products of DNA-protein reactions and real-time dynamics of DNA-protein interaction are categorized and described by the example of the most relevant research studies. The described approaches and protocols have many universal features and, therefore, are applicable for future AFM studies of various nucleic acid-protein systems.","PeriodicalId":9094,"journal":{"name":"Biophysical reviews","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45521479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An open call for contributions to a special issue of Biophysical Reviews focused on multiscale simulations of DNA from electrons to nucleosomes. 公开呼吁为《生物物理评论》特刊撰稿，重点关注DNA从电子到核小体的多尺度模拟

IF 4.9

Biophysical reviews Pub Date : 2023-08-26 eCollection Date: 2023-12-01 DOI: 10.1007/s12551-023-01118-w

Wilma K Olson, John H Maddocks, Pablo D Dans, Thomas H Cheatham, Sarah Harris, Charlie Laughton, Modesto Orozco, Lois Pollack

引用次数: 0