Brain injury最新文献

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Managing concussions in New Zealand secondary schools: Let's take it seriously. 管理新西兰中学的脑震荡:让我们认真对待它。
IF 1.5 4区 医学
Brain injury Pub Date : 2026-08-01 Epub Date: 2026-06-06 DOI: 10.1080/02699052.2026.2683510
Debbie Skilton, Anja Zoellner, Marelise Badenhorst, Kate Mossman, Danielle Salmon, Sierra Keung, Kylie Thompson, Patricia Lucas, Simon Walters, Gisela Sole
{"title":"Managing concussions in New Zealand secondary schools: Let's take it seriously.","authors":"Debbie Skilton, Anja Zoellner, Marelise Badenhorst, Kate Mossman, Danielle Salmon, Sierra Keung, Kylie Thompson, Patricia Lucas, Simon Walters, Gisela Sole","doi":"10.1080/02699052.2026.2683510","DOIUrl":"10.1080/02699052.2026.2683510","url":null,"abstract":"<p><strong>Introduction: </strong>Concussion can cause lasting cognitive, physical, and emotional challenges, impacting academic performance. New Zealand secondary schools lack sufficient knowledge and resources to support affected students. We co-designed and implemented the Framework for Management of Concussion in New Zealand Secondary Schools (FRANCS).</p><p><strong>Aim: </strong>To explore experiences and perceptions of school stakeholders during 2 years of FRANCS implementation.</p><p><strong>Methods: </strong>Sixty-nine participants from 12 schools (students, parents, staff, and healthcare providers) took part in semi-structured interviews or focus groups. Data were analyzed using framework analysis to identify themes.</p><p><strong>Results: </strong>Four themes were developed: (1) Flexibility of implementation - friend or foe; (2) Owning the process; (3) The process is too onerous; and (4) External context and confounders.</p><p><strong>Conclusion: </strong>FRANCS' flexibility enabled some schools to adapt and integrate it into existing communication pathways, supporting students' return-to-learn. Others faced challenges, resource limitations, and low engagement. Effective implementation requires initial external support to tailor FRANCS to school contexts, establish communication and monitoring systems, and embed return-to-learn processes.</p>","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"874-885"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148175411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep MAPP: a decision support tool for guideline-concordant sleep care in the polytrauma/traumatic brain injury system of care. 睡眠MAPP:在多重创伤/创伤性脑损伤护理系统中指导一致睡眠护理的决策支持工具。
IF 1.5 4区 医学
Brain injury Pub Date : 2026-08-01 Epub Date: 2026-08-02 DOI: 10.1080/02699052.2026.2705353
Adam R Kinney, Lisa A Brenner, Morgan Nance, Jeri E Forster, Samuel E King, Rishi Deka, Xiang-Dong Yan, Christi S Ulmer, Risa Nakase-Richardson, Nazanin H Bahraini
{"title":"Sleep MAPP: a decision support tool for guideline-concordant sleep care in the polytrauma/traumatic brain injury system of care.","authors":"Adam R Kinney, Lisa A Brenner, Morgan Nance, Jeri E Forster, Samuel E King, Rishi Deka, Xiang-Dong Yan, Christi S Ulmer, Risa Nakase-Richardson, Nazanin H Bahraini","doi":"10.1080/02699052.2026.2705353","DOIUrl":"10.1080/02699052.2026.2705353","url":null,"abstract":"<p><strong>Objective: </strong>First, to summarize the development of Sleep MAPP, a decision support tool designed to facilitate guideline-concordant sleep disorder care in the Veterans Health Administration (VHA) Polytrauma/Traumatic Brain Injury System of Care (PSC). Second, to assess usability, acceptability, and feasibility.</p><p><strong>Methods: </strong>We iteratively designed Sleep MAPP, including algorithms determining eligibility for guideline-concordant care using medical record data. A convergent parallel mixed-methods design elicited prototype feedback from VHA clinicians (<i>n</i> = 7). Qualitative themes were derived from semi-structured interviews and quantitative data were obtained from standardized assessments of usability, acceptability, and feasibility. A joint display was used to derive conclusions.</p><p><strong>Results: </strong>Clinicians found Sleep MAPP easy-to-use, highlighting its intuitive functionality, but suggested increased customizability. Sleep MAPP was seen as acceptable, facilitating time-efficient sleep care while improving clinical outcomes. Changes to algorithm specifications were recommended. Sleep MAPP was considered feasible due to alignment with PSC clinical workflows. Educational meetings and developing an implementation plan were recommended to enhance implementation.</p><p><strong>Conclusions: </strong>Sleep MAPP was considered usable, acceptable, and feasible to implement. Feedback will guide revisions to the tool and development of an implementation blueprint to integrate Sleep MAPP into routine PSC services, enhancing sleep care and rehabilitation outcomes among Veterans with TBI.</p>","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"994-1006"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148652955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between activities of daily living independence and observational attention ratings in patients with acute stroke. 急性脑卒中患者日常生活独立活动与观察性注意评分的关系。
IF 1.5 4区 医学
Brain injury Pub Date : 2026-06-01 Epub Date: 2026-03-11 DOI: 10.1080/02699052.2026.2642252
Takayuki Miyauchi, Shotaro Sasaki, Yudai Honda, Katsuya Sakai, Rumi Tanemura
{"title":"Association between activities of daily living independence and observational attention ratings in patients with acute stroke.","authors":"Takayuki Miyauchi, Shotaro Sasaki, Yudai Honda, Katsuya Sakai, Rumi Tanemura","doi":"10.1080/02699052.2026.2642252","DOIUrl":"10.1080/02699052.2026.2642252","url":null,"abstract":"<p><strong>Objective: </strong>As neuropsychological tests insufficiently reflect impairments in activities of daily living (ADL), behavioral observation using Moss Attention Rating Scale (MARS) is necessary. Although MARS scores are associated with ADL independence, their longitudinal relationship remains unclear. This study aimed to investigate whether changes in MARS scores over time are associated with ADL independence in patients with mild-to-moderate acute stroke who could undergo neuropsychological tests.</p><p><strong>Methods: </strong>This single-center, prospective longitudinal cohort study included 60 patients (median age: 73.5 years) hospitalized for acute stroke for ≥14 days. The median interval from stroke onset to initial evaluation was 3 days. The primary outcome was ADL independence, measured using the Barthel Index (BI) at 2 weeks.</p><p><strong>Results: </strong>Multiple regression analysis identified MARS as a significant predictor of BI at 2 weeks. Neuropsychological tests revealed floor effects, whereas MARS did not. Receiver operating characteristic curves demonstrated strong discriminative ability of MARS for predicting BI ≥ 60 (area under the curve: 0.96 [baseline], 0.93 [1 week]).</p><p><strong>Conclusions: </strong>MARS is more effective than conventional neuropsychological tests for assessing attention-related ADL independence, particularly in early stroke rehabilitation.</p><p><strong>Clinical trial registration: </strong>UMIN000055922.</p>","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"650-655"},"PeriodicalIF":1.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147430892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A closed-head, rotational traumatic brain injury model demonstrates deficits in righting reflex, neurological function, and auditory brainstem responses in rats. 闭头、旋转创伤性脑损伤模型显示了大鼠的翻正反射、神经功能和听觉脑干反应的缺陷。
IF 1.5 4区 医学
Brain injury Pub Date : 2026-06-01 Epub Date: 2026-04-10 DOI: 10.1080/02699052.2026.2654216
Michelle L Bordas, Grant D Broeckel, Katherine Sherman, Alok Shah, Matthew D Budde, Christina L Runge, Brian D Stemper, Christopher J Roberts
{"title":"A closed-head, rotational traumatic brain injury model demonstrates deficits in righting reflex, neurological function, and auditory brainstem responses in rats.","authors":"Michelle L Bordas, Grant D Broeckel, Katherine Sherman, Alok Shah, Matthew D Budde, Christina L Runge, Brian D Stemper, Christopher J Roberts","doi":"10.1080/02699052.2026.2654216","DOIUrl":"10.1080/02699052.2026.2654216","url":null,"abstract":"<p><strong>Aims: </strong>The pathophysiology of traumatic brain injury (TBI) is incompletely understood and warrants further investigation with preclinical models that recapitulate aspects of the human condition. Therefore, our goal was to quantify the initial presentation of deficits in a closed-head rotational TBI model in male and female rats in return of righting reflex (RORR) and global neurological function including gross sound reflex scores as a measure of acoustic startle.</p><p><strong>Methods: </strong>A total of 116 rats (43 female) were included in this study that underwent TBI (<i>n</i> = 53), Sham (<i>n</i> = 42), or No Anesthesia control (<i>n</i> = 21) procedures to assess RORR, the Revised Neurobehavioral Severity Scale (NSS-R), or Auditory Brainstem Responses (ABR).</p><p><strong>Results: </strong>TBI rats had a trend toward a prolonged RORR, which was significantly increased in the TBI compared to control group when normalized to the duration of anesthesia. Gross neurological function was impaired in TBI rats, such that descriptively the largest component was due to acoustic startle deficits. These deficits were not explained by worse (higher) hearing thresholds in auditory brainstem responses, although TBI rats had increased thresholds at 16 and 20 kHz, and a trend at 10 kHz compared to Shams on post-TBI day 1 that was not different by day 8.</p><p><strong>Conclusions: </strong>This model reproduces acoustic startle, and hearing impairment aspects of human TBI that influence quality of life. Additional studies are necessary to integrate variables from new clinical classification systems including blood-based and imaging biomarkers to aid in the translation to improve patient-oriented outcomes.</p>","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"684-696"},"PeriodicalIF":1.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13496039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147643963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utilizing APACHE II score for early detection of deterioration in neurosurgery ICU: a prospective cohort study. 利用APACHE II评分早期检测神经外科ICU病情恶化:一项前瞻性队列研究。
IF 1.5 4区 医学
Brain injury Pub Date : 2026-06-01 Epub Date: 2026-03-03 DOI: 10.1080/02699052.2026.2640593
Suhaimi Fauzan, Dikki Saputra, Muhammad Ibnu Kahtan, Costan Tryono Parulian Rumapea
{"title":"Utilizing APACHE II score for early detection of deterioration in neurosurgery ICU: a prospective cohort study.","authors":"Suhaimi Fauzan, Dikki Saputra, Muhammad Ibnu Kahtan, Costan Tryono Parulian Rumapea","doi":"10.1080/02699052.2026.2640593","DOIUrl":"10.1080/02699052.2026.2640593","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to evaluate the use of the Acute Physiology and Chronic Health Evaluation II (APACHE II) score as a proactive clinical tool to enhance Quality of Care (QoC), providing empirical evidence for critical nursing practice in detecting patient deterioration.</p><p><strong>Methods: </strong>This prospective cohort study analyzed 76 neurosurgery ICU patients at a tertiary referral hospital. The first 24-hour APACHE II score was calculated to determine its association with clinical deterioration within the first 48 hours. An APACHE II score of ≥16 was established as the cutoff point to stratify patients into high-risk and low-risk groups.</p><p><strong>Results: </strong>The APACHE II score demonstrated strong prognostic accuracy in predicting mortality (AUC 0.779, <i>p</i> < 0.001). Furthermore, a high-risk APACHE II score (≥16) was significantly associated with the incidence of early clinical deterioration within the first 48 hours (27.3% vs. 4.7%; <i>p</i> = 0.008).</p><p><strong>Conclusions: </strong>This study provides empirical validation of APACHE II in this neurosurgery cohort, demonstrating good prognostic accuracy. The significant association established between high initial scores and early clinical deterioration suggests its potential utility as an objective trigger for enhanced monitoring. These findings support a shift toward using the score proactively, although validation in larger multi-center cohorts is required.</p>","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"643-649"},"PeriodicalIF":1.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147347305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traumatic brain injury-related stigma among intimate partner violence survivors. 亲密伴侣暴力幸存者中与创伤性脑损伤相关的污名。
IF 1.5 4区 医学
Brain injury Pub Date : 2026-06-01 Epub Date: 2026-04-06 DOI: 10.1080/02699052.2026.2649542
Sofia Fauza, Margarita Velasco, Eve Valera, Altaf Saadi
{"title":"Traumatic brain injury-related stigma among intimate partner violence survivors.","authors":"Sofia Fauza, Margarita Velasco, Eve Valera, Altaf Saadi","doi":"10.1080/02699052.2026.2649542","DOIUrl":"10.1080/02699052.2026.2649542","url":null,"abstract":"<p><strong>Objective: </strong>Traumatic brain injury (TBI) is common among survivors of intimate partner violence (IPV), yet little is known about TBI-related stigma in this population. This qualitative study explores how such stigma affects IPV survivors, building on broader research showing its impact on recovery.</p><p><strong>Methods: </strong>We conducted individual interviews with IPV survivors with TBI. We analyzed the data using hybrid inductive-deductive thematic analysis.</p><p><strong>Results: </strong>We interviewed 20 women (mean age = 44 years, SD: 8.7, range 31-60), including 14 English speakers and 6 Spanish speakers. The largest subgroup (<i>n</i> = 7, 35%) had sustained four TBI's. We identified seven themes spanning three levels: A) Societal, B) Interpersonal, and C) Intrapersonal. At the societal level, the themes were: 1) Stigma across sectors, not limited to healthcare, and 2) Overlapping stigmas with mental health challenges. At the interpersonal level: 3) Interpersonal conflict due to negative attitudes and behaviors, and 4) Lack of understanding about TBI and symptoms. At the intrapersonal level: 5) TBI-related symptoms contributing to shame and self-discrepancy, and 6) Challenges with acceptance of TBI. The final theme cut across all levels: 7) Validation of experience as critical to post-TBI recovery.</p><p><strong>Conclusion: </strong>To support IPV survivors with TBI, practitioners must address and reduce stigma.</p>","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"674-683"},"PeriodicalIF":1.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13484952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147621751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Individual placement and support for people with acquired brain injury: feasibility and initial results. 获得性脑损伤患者的个体安置和支持:可行性和初步结果。
IF 1.5 4区 医学
Brain injury Pub Date : 2026-06-01 Epub Date: 2026-04-14 DOI: 10.1080/02699052.2026.2654830
Judith M van Velzen, Judith M Mollet, Coen A M van Bennekom, Angela G E M de Boer
{"title":"Individual placement and support for people with acquired brain injury: feasibility and initial results.","authors":"Judith M van Velzen, Judith M Mollet, Coen A M van Bennekom, Angela G E M de Boer","doi":"10.1080/02699052.2026.2654830","DOIUrl":"10.1080/02699052.2026.2654830","url":null,"abstract":"<p><strong>Purpose: </strong>To examine the feasibility of the Individual Placement and Support (IPS-)intervention for people with acquired brain injury (ABI) in the chronic phase without an employer and explore initial outcomes.</p><p><strong>Methods: </strong>A feasibility study was conducted in three Dutch institutions specialized in post-ABI work participation. Participants included five IPS employment specialists (IPS-ES), 15 clients with ABI, 13 relatives, and eight employers. Clients' IPS-counseling lasted 1 year. Data were collected through questionnaires, IPS-ES administration, and researcher-administered home assessments. Feasibility was evaluated in terms of acceptability, implementation, practicality, adaptation, and limited-efficacy testing using descriptive analyses.</p><p><strong>Results: </strong>Acceptability analyses showed median scores of 7, 8, 7, and 7 points across groups for counseling, and 8, 7, 6, and 7 points for counseling outcomes (scale 1 (not) - 10 (very satisfied)). Implementation showed reasonable model fidelity, with strengths in IPS-ES guidance and expertise, and challenges in competitive employment focus, rapid job search and placement, and integration of health and employment services. Practicality was sufficient. Several adaptations were suggested. Limited-efficacy testing showed eight of 15 clients (53%) obtaining paid work.</p><p><strong>Conclusion: </strong>IPS appeared feasible: Implementation was reasonably model-faithful, stakeholders were satisfied, and >50% achieved paid employment. Broader implementation is recommended, addressing identified challenges and continuing evaluation.</p>","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"705-716"},"PeriodicalIF":1.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147670340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When head trauma/brain injury is no longer an accident. 当头部外伤/脑损伤不再是意外事故时。
IF 1.5 4区 医学
Brain injury Pub Date : 2026-06-01 Epub Date: 2026-03-23 DOI: 10.1080/02699052.2026.2648718
Alexis Demas, Emmanuel Orhant
{"title":"When head trauma/brain injury is no longer an accident.","authors":"Alexis Demas, Emmanuel Orhant","doi":"10.1080/02699052.2026.2648718","DOIUrl":"10.1080/02699052.2026.2648718","url":null,"abstract":"","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"722-723"},"PeriodicalIF":1.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147503000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of cognitive-vocational rehabilitation on post-concussion symptoms and emotional distress: a secondary RCT analysis. 认知-职业康复对脑震荡后症状和情绪困扰的影响:一项二次RCT分析。
IF 1.5 4区 医学
Brain injury Pub Date : 2026-06-01 Epub Date: 2026-04-19 DOI: 10.1080/02699052.2026.2654829
Nada Andelic, Juan Lu, Silje C R Fure, Cathrine Brunborg, Marianne Løvstad, Cecilie Røe, Emilie Isager Howe
{"title":"Effects of cognitive-vocational rehabilitation on post-concussion symptoms and emotional distress: a secondary RCT analysis.","authors":"Nada Andelic, Juan Lu, Silje C R Fure, Cathrine Brunborg, Marianne Løvstad, Cecilie Røe, Emilie Isager Howe","doi":"10.1080/02699052.2026.2654829","DOIUrl":"10.1080/02699052.2026.2654829","url":null,"abstract":"<p><strong>Objective: </strong>To examine the long-term effects of a combined Compensatory Cognitive Training and Supported Employment (CCT-SE) intervention on post-concussion symptoms (PCS) and emotional distress in individuals with mild-to-moderate traumatic brain injury (TBI) on sick leave 8-12 weeks post-injury.</p><p><strong>Methods: </strong>In this secondary analysis of a randomized controlled trial at Oslo University Hospital, 116 working-age adults were randomized to CCT-SE or treatment as usual (TAU). CCT-SE consisted of a 10-week cognitive rehabilitation program and up to 6 months of individualized vocational support. Outcomes included PCS (Rivermead Post-Concussion Symptoms Questionnaire, RPQ), depression (PHQ-9), and anxiety (GAD-7), assessed at 3, 6, and 12 months. Linear mixed-effects models evaluated group differences over time.</p><p><strong>Results: </strong>At baseline, participants reported a moderate-to-severe PCS burden (mean RPQ 28, SD 11); 38% had moderate-to-severe depressive symptoms and 17% moderate-to-severe anxiety. The CCT-SE group showed significantly greater improvement in RPQ cognitive scores at 12 months versus TAU. No between-group differences were found for PHQ-9, GAD-7, or RPQ somatic and emotional subscales, though both groups demonstrated significant within-group improvement across all outcomes.</p><p><strong>Conclusions: </strong>Early cognitive and vocational rehabilitation may benefit individuals with persistent cognitive symptoms after mild-to-moderate TBI. Given the prevalence of emotional distress, integrating psychological interventions may strengthen CCT-SE.</p>","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"697-704"},"PeriodicalIF":1.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147721826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Objective oculomotor markers of mTBI: a three-timepoint case report. 目的mTBI的动眼肌指标:三个时间点病例报告。
IF 1.5 4区 医学
Brain injury Pub Date : 2026-06-01 Epub Date: 2026-03-30 DOI: 10.1080/02699052.2026.2651864
Alice Cade, Kirk Stevens, Philip R K Turnbull
{"title":"Objective oculomotor markers of mTBI: a three-timepoint case report.","authors":"Alice Cade, Kirk Stevens, Philip R K Turnbull","doi":"10.1080/02699052.2026.2651864","DOIUrl":"10.1080/02699052.2026.2651864","url":null,"abstract":"<p><strong>Background: </strong>Mild traumatic brain injury (mTBI) is typically assessed using subjective symptom reports, yet subtle neurophysiological disruption may persist beyond clinical recovery. Eye-tracking provides an objective index of cognitive, sensorimotor, and autonomic function, particularly when implemented in immersive three-dimensional (3D) virtual reality (VR). This case report describes changes in 3D VR eye-tracking before, immediately following, and with recovery from mTBI.</p><p><strong>Case presentation: </strong>A 49-year-old male completed baseline testing as part of a larger study, then sustained an mTBI 10 weeks later. Eye-tracking was repeated at 1 week ('Injury') and ~11 weeks post-injury ('Recovery'). The battery assessed fixation, pursuit, saccades, inhibitory control (anti-saccade and Stroop), vestibulo-ocular reflex (VOR), egocentric localization, and pupillary light reflex (PLR).</p><p><strong>Results: </strong>Injury-phase demonstrated widespread alterations in precision, inhibitory control, and autonomic metrics. Fixation BCEA increased 4.8-14.8%. Pursuit, fixation, and VOR error worsened. VOR gain worsened (1.04 to 0.79) but showed partial recovery (0.85). Anti-saccade accuracy declined (87.5% to 62.5%). Stroop accuracy improved; however, latency increased substantially, suggesting compensation. PLR constriction amplitude decreased by ~50%.</p><p><strong>Conclusion: </strong>This case demonstrates multi-domain oculomotor disturbance post-mTBI, with persistent abnormalities despite symptom improvement. Immersive 3D VR eye-tracking may provide a sensitive, objective method for detecting neurophysiological dysfunction and monitoring recovery.</p>","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"717-721"},"PeriodicalIF":1.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147580423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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