Brain injury最新文献_第6页

Successful cognitive rehabilitation for acute right frontal aslant tract injury with impaired working memory and inattention using diffusion tensor tractography. 急性右额斜束损伤伴工作记忆和注意力不集中的成功认知康复。

IF 1.8 4区医学

Brain injury Pub Date : 2025-08-01 Epub Date: 2025-04-12 DOI: 10.1080/02699052.2025.2490974

Masaharu Sawaki, Kazuya Motomura, Hiroyasu Yamamoto, Koei Ito, Yuto Suzuki, Masahiko Yamamoto

{"title":"Successful cognitive rehabilitation for acute right frontal aslant tract injury with impaired working memory and inattention using diffusion tensor tractography.","authors":"Masaharu Sawaki, Kazuya Motomura, Hiroyasu Yamamoto, Koei Ito, Yuto Suzuki, Masahiko Yamamoto","doi":"10.1080/02699052.2025.2490974","DOIUrl":"10.1080/02699052.2025.2490974","url":null,"abstract":"Background: Language impairments caused by left frontal aslant tract (FAT) damage have a good prognosis. However, the prognosis of cognitive dysfunction after right FAT injury is unknown. The present study describes successful cognitive rehabilitation for impaired working memory and inattention together with diffusion tensor tractography (DTT).Methods: A patient in his 40s with acute stroke underwent magnetic resonance imaging, computed tomography perfusion scans, DTT, and 11 neuropsychological tests for attention, frontal lobe, memory, visuospatial, intelligence, and cognitive functions. Three weeks of cognitive rehabilitation, including direct attention and metacognitive strategy training, and visual working memory tasks were performed. DTT and neuropsychological assessments were compared before and after rehabilitation.Results: Neuropsychological scores in the Trail Making Test, Clinical Assessment for Attention, and Frontal Assessment Battery increased with step-by-step rehabilitation, leading to early reinstatement as a system engineer. DTT revealed that the FAT posterior segment adjacent to the lesion increased its distal branching in the inferior frontal gyrus.Conclusion: In this case study, cognitive rehabilitation for three weeks restored impaired working memory and attention while enhancing right FAT integrity. Visualizing white matter using DTT in the acute phase provides essential insights for selecting appropriate training tasks to facilitate functional recovery from neuropsychological disturbances.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"886-892"},"PeriodicalIF":1.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The assessment of mood in people with severe cognitive and communication impairments following brain injury: a survey of UK-based professionals. 脑损伤后严重认知和沟通障碍患者的情绪评估：英国专业人士的一项调查。

IF 1.8 4区医学

Brain injury Pub Date : 2025-08-01 Epub Date: 2025-04-20 DOI: 10.1080/02699052.2025.2493354

Alexandra E Rose, Breda Cullen, Sarah Crawford, Jonathan J Evans

{"title":"The assessment of mood in people with severe cognitive and communication impairments following brain injury: a survey of UK-based professionals.","authors":"Alexandra E Rose, Breda Cullen, Sarah Crawford, Jonathan J Evans","doi":"10.1080/02699052.2025.2493354","DOIUrl":"10.1080/02699052.2025.2493354","url":null,"abstract":"Aim: Assessing mood via standardized measures and clinical interviews is challenging in people with ongoing cognitive and receptive communication impairments after a severe brain injury. This study examined how healthcare professionals in the United Kingdom assess this population via two online surveys, one of clinical psychologists (CPs) and one of medical professionals (MPs).Method: Recruitment was completed via social media and invitational e-mails to identified services, professional bodies and special interest groups. Survey responses were via multiple choice and free text. Responses were analyzed using descriptive statistics and content analysis.Results: 55 CPs and 29 MPs responded. All respondents reported asking others about the patient's mood, and the majority of both groups interview and observe the patient. 86% of CPs and 45% of MPs use standardized measures. Most of the CPs made adaptations to the measures, as did more than a third of MPs. The majority of both groups made adaptations to the scores.Conclusions: Most clinicians assessing mood in this population ask others about the person. Mood measures are used, but the administration and score interpretation are frequently adapted, bringing the validity of the use of measures in this population into question. Although there was overlap regarding methods used by surveyed clinicians, there was no clear consensus on how mood should be assessed in this population.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"947-962"},"PeriodicalIF":1.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An iterative ROC procedure identifies white matter tracts diagnostic for traumatic brain injury: an exploratory analysis in U.S. Veterans. 一个反复的ROC程序确定白质束诊断创伤性脑损伤：在美国退伍军人的探索性分析。

IF 1.8 4区医学

Brain injury Pub Date : 2025-08-01 Epub Date: 2025-04-21 DOI: 10.1080/02699052.2025.2492746

Keith L Main, Andrei A Vakhtin, Jiachen Zhuo, Donald Marion, Maheen M Adamson, J Wesson Ashford, Rao Gullapalli, Ansgar J Furst

{"title":"An iterative ROC procedure identifies white matter tracts diagnostic for traumatic brain injury: an exploratory analysis in U.S. Veterans.","authors":"Keith L Main, Andrei A Vakhtin, Jiachen Zhuo, Donald Marion, Maheen M Adamson, J Wesson Ashford, Rao Gullapalli, Ansgar J Furst","doi":"10.1080/02699052.2025.2492746","DOIUrl":"10.1080/02699052.2025.2492746","url":null,"abstract":"Objective: Understanding the pathophysiology of traumatic brain injury (TBI) is crucial for effectively managing care. Diffusion tensor imaging (DTI) is an MRI technology that evaluates TBI pathology in brain white matter. However, DTI analysis generates numerous measures. Choosing between them remains an obstacle to clinical translation. In this study, we leveraged an iterative receiver operating characteristic (ROC) analysis to examine white matter tracts in a group of 380 Veterans, consisting of TBI (n = 243) and non-TBI patients (n = 137).Method: For each participant, we obtained a whole brain tractography and extracted DTI measures from 50 tracts. The ROC analyzed these variables and produced decision trees of tracts diagnostic for TBI. We expanded our findings by applying jackknife resampling. This procedure removed potential outliers and yielded tracts not observed in the initial ROCs. Finally, we used logistic regression to confirm the tracts predicted TBI status.Results: Our results indicate ROC can identify tracts diagnostic for TBI. We also found that groups of tracts are more predictive than any single one.Conclusions: These analyses show that ROC is a useful tool for exploring large, multivariate datasets and may inform the design of clinical algorithms.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"867-885"},"PeriodicalIF":1.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Traumatic brain injury in adolescents: the relationship between high school exiting status and future productivity. 青少年创伤性脑损伤：高中退出状态与未来生产力的关系。

IF 1.5 4区医学

Brain injury Pub Date : 2025-08-01 Epub Date: 2025-04-21 DOI: 10.1080/02699052.2025.2489599

Jeffrey S Garofano, Claire H Pak

{"title":"Traumatic brain injury in adolescents: the relationship between high school exiting status and future productivity.","authors":"Jeffrey S Garofano, Claire H Pak","doi":"10.1080/02699052.2025.2489599","DOIUrl":"10.1080/02699052.2025.2489599","url":null,"abstract":"Objective: Investigate the relationship between high school exiting type and productivity in post-secondary education and employment among students who suffered a moderate-to-severe traumatic brain injury (TBI) while in high school.Methods: This retrospective cohort study included 225 16-18-year-old students who attended neurorehabilitation after a moderate-to-severe TBI. All injuries occurred while attending high school; all youth attended neurorehabilitation at a TBI Model Systems Hospital. We measured productivity as mean weekly hours in post-secondary education and employment 5 years post-injury. We examined the unique contribution of high school exiting type to long-term productivity with hierarchical linear regressions, controlling for patient demographics, pre-injury factors, and injury/disability severity.Results: Most participants (82%) graduated high school with a diploma. Graduates reported more weekly productivity hours (23.61) than those who exited with a General Educational Development (GED) (12.85) or non-completers (5.97). All control variables contributed significantly to 5-year productivity and a diploma or GED was uniquely related to productivity.Conclusions: Graduating high school is attainable for most youth who experience a TBI during high school. Graduating with a diploma or GED was uniquely related to 5-year productivity, providing a clear incentive for collaboration between neurorehabilitation services and schools.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"840-846"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exosomes beyond stem cells during traumatic brain injury: hype or hope? 外伤性脑损伤中干细胞外泌体：炒作还是希望？

IF 1.5 4区医学

Brain injury Pub Date : 2025-08-01 Epub Date: 2025-06-10 DOI: 10.1080/02699052.2025.2489592

Mehrdad Hajinejad, Mahsa Abedi, Sajad Sahab Negah

{"title":"Exosomes beyond stem cells during traumatic brain injury: hype or hope?","authors":"Mehrdad Hajinejad, Mahsa Abedi, Sajad Sahab Negah","doi":"10.1080/02699052.2025.2489592","DOIUrl":"10.1080/02699052.2025.2489592","url":null,"abstract":"Background: Based on the available data, stem cell therapy is a hopeful cure option for neurotrauma, especially traumatic brain injury. Stem cells can improve neurological outcomes and promote neuroregeneration after an injury through mechanisms such as bystander effects, cell replacement, and the activation of endogenous pathways. However, several uncertainties and limitations exist in achieving appropriate results and applying stem cell therapy at the clinical level. This study performed an extensive review of a pertinent database, utilizing targeted keywords to extract information regarding the application of stem cells and their exosomes in the context of brain injury. It also examined the distinctions between these two modalities in therapeutic strategies.Results: Recent research has demonstrated that exosomes, which are small extracellular vesicles, can overwhelm boundaries associated with stem cell therapy, such as issues with bioavailability and immune responses. A comprehensive review article is needed to discuss the benefits and drawbacks of using stem cell products, including exosomes, for treating traumatic brain injury (TBI).Conclusion: Therefore, exosome therapy has garnered significant attention in stem cell-based therapy for brain injuries. However, further research is needed to explore its mechanisms.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"797-808"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient voices to enhance concussion research participation: an exploratory qualitative study. 患者声音增强脑震荡研究参与：一项探索性质的研究。

IF 1.8 4区医学

Brain injury Pub Date : 2025-07-30 DOI: 10.1080/02699052.2025.2531984

Cindy Hunt, Maryam Fereig, Sarah Diaz, Elke McLellan, Shannon Kenrick-Rochon, Andrew Baker

{"title":"Patient voices to enhance concussion research participation: an exploratory qualitative study.","authors":"Cindy Hunt, Maryam Fereig, Sarah Diaz, Elke McLellan, Shannon Kenrick-Rochon, Andrew Baker","doi":"10.1080/02699052.2025.2531984","DOIUrl":"https://doi.org/10.1080/02699052.2025.2531984","url":null,"abstract":"Purpose: There are unique characteristics of vulnerability among adult patients who experience a concussion and have persistent symptoms suggesting the need to tailor recruitment and retention strategies for this population. We aimed to obtain perspectives from post-concussion patients regarding factors they value to encourage recruitment and support retention, thereby assisting research teams conducting studies on concussion.Methods: The authors used purposive, nonrandom sampling to identify potential research participants for this exploratory qualitative sub-study. Interview questions were designed using Appreciative Inquiry to gain patient-centered approaches to support recruitment and retention. Transcripts from telephone interviews were analyzed using reflexive thematic analysis.Results: We identified two main themes: 1) positive change and 2) participant-centered study design. Each main theme had three sub-themes to support recruitment and/or retention. Positive changes included a) meaningful study impact, b) personal contribution counts, and c) gain information, and reassurance. Participant-centered study design included a) convenience, b) accommodation, and c) feeling valued.Conclusions: Focused efforts in planning to recruit and retain vulnerable populations for research are paramount. Based on our exploratory findings from a limited sample, we offer patient-reported insights to reflect upon the ongoing learning process to optimize recruitment and retention in the field of concussion research.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-13"},"PeriodicalIF":1.8,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of concussion on the cardiac autonomic nervous system of adolescents: a systematic review. 脑震荡对青少年心脏自主神经系统的影响：一项系统综述。

IF 1.8 4区医学

Brain injury Pub Date : 2025-07-28 DOI: 10.1080/02699052.2025.2535625

Keshen Pathmanathan, Ewan Maidment, Simon M Walker

{"title":"The impact of concussion on the cardiac autonomic nervous system of adolescents: a systematic review.","authors":"Keshen Pathmanathan, Ewan Maidment, Simon M Walker","doi":"10.1080/02699052.2025.2535625","DOIUrl":"https://doi.org/10.1080/02699052.2025.2535625","url":null,"abstract":"Introduction: Concussions pose a serious threat to adolescents, with potential long-term effects. This systematic review considers whether cardiac autonomic nervous system dysfunction occurs post-concussion in adolescents.Methods: Eight databases were searched on 30/5/24 using terms related to adolescents, concussion, and the cardiac autonomic nervous system. Included were full-text English articles comparing heart rate, blood pressure, or heart rate variability among adolescents with concussion history and controls. JBI critical appraisal tools assessed methodological quality. Meta-analysis was not performed due to inter-study methodological variations.Results: Ten studies met the inclusion criteria. Two studies included participants with longer-term concussion histories. Eight studies involved exertion. Mixed results were found for all metrics. A greater percentage of results was significant during exertion; the lowest percentage was for resting heart rate variability (15%), whilst the highest was for heart rate under exertion (46.15%). Critical appraisal highlights methodological flaws. Studies often inappropriately manage confounding factors, and some selected controls inappropriately, such as using individuals with a history of concussion as controls.Discussion: Evidence suggests possible cardiac autonomic dysfunction post-concussion, more apparent under exertion. Methodological limitations prevent definitive conclusions. Future research should better manage confounding factors to determine whether cardiac autonomic assessment can assist concussion diagnosis and management.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-17"},"PeriodicalIF":1.8,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144727764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain injury medicine fellowship program growth and application rates: 2017 to 2024. 脑损伤医学奖学金项目增长和申请率：2017年至2024年。

IF 1.5 4区医学

Brain injury Pub Date : 2025-07-23 DOI: 10.1080/02699052.2025.2538553

Jason Silvestre, Lindsay Mohney, Ameet S Nagpal, James P Lawrence, Robert A Ravinsky

{"title":"Brain injury medicine fellowship program growth and application rates: 2017 to 2024.","authors":"Jason Silvestre, Lindsay Mohney, Ameet S Nagpal, James P Lawrence, Robert A Ravinsky","doi":"10.1080/02699052.2025.2538553","DOIUrl":"https://doi.org/10.1080/02699052.2025.2538553","url":null,"abstract":"Background: The American Board of Medical Specialties recognized brain injury medicine (BIM) as a subspecialty certification for physicians from diverse training backgrounds. Increasing the number of physicians pursuing BIM fellowship training remains imperative given the increasing prevalence of patients with traumatic brain injuries.Methods: This was a retrospective cohort study of BIM fellowship applicants from 2017 to 2024. The annual volume of available training positions, applications, match rates, and unfilled training positions were calculated.Results: The annual volume of BIM training programs (16 to 26, 63% increase), training positions (17 to 31, 82% increase), and applicants (16 to 26, 63% increase) increased over the study period (p < 0.001). The annual applicant-to-training position ratio ranged between 0.7-1.2 with no significant change over the study period (p = 0.598). In total, there were 198 available training positions and 39 went unfilled (20%). The rate of unfilled training positions (12% to 16%, p = 0.601) and annual match rates (94%-100%, p = 0.958) did not change. Most applicants matched at their first-choice (45%) or second-choice (16%) fellowship programs.Conclusions: There were 198 BIM fellowship positions available over the study period and 39 went unfilled (20%). Coordinated efforts may stimulate earlier physician interest in BIM training to meet future demands.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-4"},"PeriodicalIF":1.5,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Waiting time for specialized interdisciplinary rehabilitation associated with persistent symptoms of mild traumatic brain injury: an observational cohort study. 与轻度创伤性脑损伤持续性症状相关的专业跨学科康复等待时间：一项观察性队列研究

IF 1.5 4区医学

Brain injury Pub Date : 2025-07-22 DOI: 10.1080/02699052.2025.2530083

Julien Déry, Isabelle Potvin, Élaine De Guise, Marie-Eve Lamontagne

{"title":"Waiting time for specialized interdisciplinary rehabilitation associated with persistent symptoms of mild traumatic brain injury: an observational cohort study.","authors":"Julien Déry, Isabelle Potvin, Élaine De Guise, Marie-Eve Lamontagne","doi":"10.1080/02699052.2025.2530083","DOIUrl":"https://doi.org/10.1080/02699052.2025.2530083","url":null,"abstract":"Introduction: Approximately thirty percent of patients with mild traumatic brain injury (mTBI) suffer from persistent symptoms that can impact their day-to-day activities. The primary aim of this study was to examine the relationship between waiting time for rehabilitation services and persistent post-mTBI symptoms. The secondary objective was to explore the relationship between sociodemographic characteristics and persistent symptoms.Materials and methods: An observational cohort study was conducted at a specialized interdisciplinary rehabilitation program for mTBI in Québec, Canada. Waiting time was the predictor variable and symptom outcomes were measured at two points in time.Results: Twenty-six participants completedquestionnaires at both baseline and follow-up. Approximately 70% of participants received their first appointment within six months of the injury, while the others waited more than eight months. Longer waiting times were associated with higher scores of persistent post-concussion symptoms on the Rivermead Post-Concussion Symptoms Questionnaire (p = 0.008), higher scores on the Beck Anxiety Inventory (p = 0.005), and lower scores on the Community Integration Questionnaire (p = 0.006) at baseline, as well as higher scores on the Beck Anxiety Inventory (p = 0.046) at follow-up.Conclusion: This study reveals the negative effects of delayed access to specialized rehabilitation services for patients with mTBI and calls for necessary policy changes.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-10"},"PeriodicalIF":1.5,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alexithymia predicts face emotion perception after acquired brain injury. 述情障碍预测后发性脑损伤后的面部情绪知觉。

IF 1.5 4区医学

Brain injury Pub Date : 2025-07-12 DOI: 10.1080/02699052.2025.2531981

Rebecca De La Garza, Lisa J Rapport, Robiann R Broomfield, Emily Flores, Robin A Hanks, Mark A Lumley, Lauren J Radigan

{"title":"Alexithymia predicts face emotion perception after acquired brain injury.","authors":"Rebecca De La Garza, Lisa J Rapport, Robiann R Broomfield, Emily Flores, Robin A Hanks, Mark A Lumley, Lauren J Radigan","doi":"10.1080/02699052.2025.2531981","DOIUrl":"https://doi.org/10.1080/02699052.2025.2531981","url":null,"abstract":"Background: This study investigated the presence and level of alexithymia and examined the relationship between alexithymia and affect recognition abilities after acquired brain injury (ABI), accounting separately for etiology due to stroke or traumatic brain injury (TBI).Methods: Ninety-nine neurologically healthy adults (NHA) and 119 adults with moderate-to-severe ABI (63 TBI, 56 stroke) participated. Main measures included the Toronto Alexithymia Scale-20 (TAS-20) and Multicultural Facial Emotion Perception Test (MFEPT).Results: ABI groups endorsed greater alexithymia than NHA, but TBI and stroke subgroups did not significantly differ. Hierarchical multiple regression indicated that TAS-20 subscales difficulty identifying feelings (DIF) and externally oriented thinking (EOT), but not Difficulty Describing Feelings (DDF), added unique value to predicting objective affect recognition (MFEPT) after accounting for age, education, sex, face recognition ability, and general cognitive function. Moreover, the relationship between alexithymia and affect recognition was moderated by group: DIF and DDF were inversely related to MFEPT only for adults with ABI. EOT was inversely related to affect recognition for all three groups.Conclusions: Adults with ABI experience alexithymia more frequently and intensely than neurologically healthy adults, and this impairment may partly underlie struggles with affective processing frequently observed in these individuals on experimental tasks and in real-world interactions.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-9"},"PeriodicalIF":1.5,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144616177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0