BMC GeriatricsPub Date : 2025-05-13DOI: 10.1186/s12877-025-05976-9
Lea Kromann Johansen, Trine Schifter Larsen, Jeanette Wassar Kirk, Britt Staevnsbo Pedersen, Barbara Rubek Nielsen, Thomas Kallemose, Thomas Bandholm, Mette Merete Pedersen
{"title":"Exploring in-hospital mobility practices for geriatric patients: insights from a mixed-method study.","authors":"Lea Kromann Johansen, Trine Schifter Larsen, Jeanette Wassar Kirk, Britt Staevnsbo Pedersen, Barbara Rubek Nielsen, Thomas Kallemose, Thomas Bandholm, Mette Merete Pedersen","doi":"10.1186/s12877-025-05976-9","DOIUrl":"10.1186/s12877-025-05976-9","url":null,"abstract":"<p><strong>Background: </strong>It is well-established that mobility is very limited among older hospitalized patients and associated with several negative outcomes. Therefore, this mixed-methods study aimed to quantify 24-hour mobility levels in acutely admitted older adults and simultaneously explore clinical practice with regards to mobilization and mobility through an ethnographic field study.</p><p><strong>Methods: </strong>Over a 6-week period, hospital mobility was assessed in 44 geriatric patients by SENS motion<sup>®</sup> activity sensors that the patients wore continuously for 24 h a day during their hospitalization. An ethnographic field study was conducted alongside the cohort study. It included participant observation on the ward and situated conversations with staff, patients, and relatives 2-3 times a week for 4-5 h at different times of the day. The observations were noted in field notes. Activity data were aggregated into a per day measure based on the mean of all available days for a given patient. Also, the per day measures were stratified by walking dependency (walking with or without a walking aid). The field notes were analyzed through a thematic analysis.</p><p><strong>Results: </strong>During hospitalization, the patients spent most of their time (22.8 h/per day) in sedentary behavior and only 1.2 h/per day in uptime (walking and standing), including 43 min walking, and took less than 1200 steps daily. The field study revealed that most staff consider mobilization and mobility important tasks. However, mobilizing patients to a chair and performing functional level assessments are prioritized over patient mobility. Also, the patients' perceived mobility opportunities are limited by the physical environment (e.g., congested hallways) and lack of purposeful activities to engage in.</p><p><strong>Conclusions: </strong>This study found low levels of mobility in geriatric inpatients during hospitalization. While mobility is considered important, mobilization to a chair and functional assessments are prioritized over patient mobility, which becomes dependent on the patient's own initiative. Therefore, environmental adjustment, enhanced interprofessional collaboration, and targeted strategies for integrating mobility into daily care practices are warranted to enhance in-hospital mobility. ClincalTrials.Gov identifier NCT06421246.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"330"},"PeriodicalIF":3.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12070506/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC GeriatricsPub Date : 2025-05-10DOI: 10.1186/s12877-025-06005-5
Lynn Janssens, I Phlypo, A Geddis-Regan, M Petrovic, B Janssens
{"title":"Care home managers' perspectives on domiciliary dental care: a qualitative study.","authors":"Lynn Janssens, I Phlypo, A Geddis-Regan, M Petrovic, B Janssens","doi":"10.1186/s12877-025-06005-5","DOIUrl":"https://doi.org/10.1186/s12877-025-06005-5","url":null,"abstract":"<p><strong>Background: </strong>Domiciliary dental care (DDC) is an established, safe and cost-effective alternative to standard care which can increase accessibility to professional dental care for care-dependent individuals. Qualitative research with care home managers has explored current practices and specific barriers to accessing dental care services: this has highlighted problems with dentist availability, accessibility and financial concerns. No research has explored reported experiences of DCC implementation in care home settings.</p><p><strong>Purpose: </strong>This study aimed to explore care home manager's perspectives and preferences on DDC following its wider implementation.</p><p><strong>Methods: </strong>The study used a qualitative approach in a constructivist paradigm. Six semi-structured face-to-face interviews were conducted with ten care home managers from a purposive sample of care homes participating in DDC. Interviews were audio-recorded, transcribed verbatim, and analysed using reflexive thematic analysis.</p><p><strong>Results: </strong>Five major themes were defined. Care home managers preferred DDC to avoid logistical challenges and stress for residents, highlighting the need for on-site dental services. While they wished for reliable partnerships with locally based oral health professionals, this was seen as unrealistic due to their limited willingness to treat care home residents. DDC was valued for its accessibility and support, yet financial concerns were raised due to increasing costs associated with DDC. Managers also emphasized the importance of stable oral care teams within the care home; they noted, however, that this was difficult to achieve due to high staff turnover in long-term care.</p><p><strong>Conclusion: </strong>Domiciliary dental care was widely accepted and appreciated by the care home managers in this study, but increasing costs presented a significant threat to its sustainability.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"323"},"PeriodicalIF":3.4,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC GeriatricsPub Date : 2025-05-10DOI: 10.1186/s12877-025-06008-2
Lisa A Juckett, Shivam Joshi, J Madison Hyer, Govind Hariharan, Kali S Thomas, Tejeswini Siva Sathya, Mequeil L Howard, Leah E Bunck, Melinda L Rowe, Andrea Devier, Kelly Parrett
{"title":"Occupational therapy and registered dietitian services to reduce fall risk among home delivered meal clients: a randomized controlled feasibility trial.","authors":"Lisa A Juckett, Shivam Joshi, J Madison Hyer, Govind Hariharan, Kali S Thomas, Tejeswini Siva Sathya, Mequeil L Howard, Leah E Bunck, Melinda L Rowe, Andrea Devier, Kelly Parrett","doi":"10.1186/s12877-025-06008-2","DOIUrl":"10.1186/s12877-025-06008-2","url":null,"abstract":"<p><strong>Background: </strong>Older adults increasingly prefer to age in place, but health and safety risks often threaten this independence. Home delivered meals, a key service under the Older Americans Act, provide essential nutritional support to homebound older adults, the majority of whom are at elevated risk for fall-related morbidity and mortality. Given the complex health conditions of homebound older adults, we conducted a feasibility randomized controlled trial (RCT) to evaluate our methods for testing four different service models designed to help reduce fall risk among home delivered meal recipients: (1) meals alone; (2) meals + registered dietitian nutritionist (RDN) services; (3) meals + occupational therapy (OT) services; or (4) meals + RDN + OT services. Findings will inform protocol modifications for our definitive RCT to improve fall-related outcomes among this population.</p><p><strong>Methods: </strong>A four-arm, parallel-group feasibility RCT was conducted with one home delivered meal agency in the Midwest United States. Participants were eligible to participate if they were over 60 years old, were able to receive meals from our partner agency, had one diet-related health condition, and were at risk for falling. Feasibility outcomes included study eligibility, recruitment, retention, fidelity to RDN and OT services, and service acceptability.</p><p><strong>Results: </strong>Of 442 screened clients, 31% were eligible for participation, and 41% of eligible individuals were recruited (N = 56). Retention at three months was 79%. Fidelity rates were 84.5% for RDN services and 90.2% for OT services. Participants expressed high satisfaction with meal convenience and staff interactions but noted areas for improvement, including meal taste and inconsistent meal deliveries (e.g., timeliness; receiving correct meals).</p><p><strong>Conclusions: </strong>The study identified several barriers to scaling this trial, including restrictive eligibility criteria and recruitment challenges. Protocol modifications for the definitive trial include broader eligibility, expanded recruitment areas, and increased flexibility in meal selection. Randomization procedures will also be adjusted to account for participants from the same household. This feasibility trial demonstrates the potential for integrating RDN and OT services into home delivered meal programs to address recipients' fall-related needs.</p><p><strong>Trial registration: </strong>Clinicaltrials.gov; NCT06059404; 22/09/2023.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"325"},"PeriodicalIF":3.4,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of planning of the integrated care for older people in China: a theory of change approach.","authors":"Biyan Jiang, Baiyu Li, Shijia He, Lingyan Chen, Shulan Yang, Jiabin Liu, Weimin Lou, Yiyu Hu, Xiaoqing Jin, Caixia Liu","doi":"10.1186/s12877-025-05956-z","DOIUrl":"https://doi.org/10.1186/s12877-025-05956-z","url":null,"abstract":"<p><strong>Background: </strong>Integrated Care for Older People (ICOPE), developed by the World Health Organization (WHO) with a global perspective, faces varying degrees of barriers to implementation, particularly in middle-and low-income countries. Therefore, as with other new public service interventions, we draw on established integrated care interventions to design a Theory of Change (ToC) model for ICOPE, and to propose methods and pathways for adapting community-based integrated care models for older people (OP) to specific contexts, thereby updating and enhancing the implementation of ICOPE.</p><p><strong>Methods: </strong>An initial ToC for the ICOPE was drafted based on the WHO guidelines and published literature, and synthesizing the results of semi-structured interviews, group discussions. A total of 36 healthcare stakeholder experts in geriatric nursing, geriatric care and chronic disease management, rehabilitation and quality of life, and psychiatric-mental health were recruited to participate in a 5-stage ToC group workshop conducted consecutively. Each workshop has 2-3 facilitators, and lasts from 60 to 120 min. In multiple workshops, the experts discussed the causal pathway, the interventions needed to activate it, the underlying principles and assumptions, evaluated and refined them, and finally reached consensus.</p><p><strong>Results: </strong>The ToC design has improved the ICOPE program, identifying the resources, long-term outcomes, and impacts required for the implementation of ICOPE in a specific setting, and clarifying the specific components of the integrated care interventions, such as materials, procedures, and intervention providers. The localized, OP-centred model of integrated home care developed in our study may contribute to healthy ageing through four potential long-term outcomes: (1) reduction of unnecessary hospitalizations and increased utilization of referral services, (2) enhancement of self-care capacity to prevent, reverse, or delay the decline of intrinsic capacity in OP, (3) improvement of the quality of life of OP living at home, and (4) reduction of caregiving burdens and improvement in the level of caregiving.</p><p><strong>Conclusion: </strong>The ToC is effective in identifying key characteristics of resources, interventions, impact, and outcomes of integrated care for OP. Our ICOPE program has been strengthened by ToC, which forms an integrated care model for assessment, planning, implementation, and evaluation, adapted to a specific setting, and provides guidance for other areas in similar settings.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"324"},"PeriodicalIF":3.4,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Construction and validation of a predictive model for suicidal ideation in non-psychiatric elderly inpatients.","authors":"Shuyun Xiong, Dongxu Si, Meizhu Ding, Cuiying Tang, Jinling Zhu, Danni Li, Ying Lei, Lexian Huang, Xiaohua Chen, Jicai Chen","doi":"10.1186/s12877-025-05980-z","DOIUrl":"https://doi.org/10.1186/s12877-025-05980-z","url":null,"abstract":"<p><strong>Background: </strong>Suicide poses a substantial public health challenge globally, with the elderly population being particularly vulnerable. Research into suicide risk factors among elderly inpatients with non-psychiatric disorders remains limited. This investigation focused on crafting a machine learning-based prediction model for suicidal ideation (SI) in this population to aid suicide prevention efforts in general hospitals.</p><p><strong>Methods: </strong>A total of 807 non-psychiatric elderly inpatients aged over 60 were assessed using demographic and clinical data, and SI was measured using the Patient Health Questionnaire-9 (PHQ-9). Data were processed utilizing machine learning algorithms, and predictive models were developed using multiple logistic regression, Nomogram, and Random Forest models.</p><p><strong>Results: </strong>Key predictors included PHQ-8, Athens Insomnia Scale, hospitalization frequency, Perceived Social Support from Family scale, comorbidities, income, and employment status. Both models demonstrated excellent predictive performance, with AUC values exceeding 0.9 for both training and test sets. Notably, the Random Forest model outperformed others, achieving an AUC of 0.958, with high accuracy (0.952), precision (0.962), sensitivity (0.987), and an F1 score of 0.974.</p><p><strong>Conclusion: </strong>These models offer valuable tools for suicide risk prediction in elderly non-psychiatric inpatients, supporting clinical prevention strategies.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"322"},"PeriodicalIF":3.4,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC GeriatricsPub Date : 2025-05-09DOI: 10.1186/s12877-025-05972-z
Janaia Utas, Tasmin Adel, Charlotte Jensen, Stephanie A Chamberlain, Jennifer Baumbusch, Sharon Anderson, Jasneet Parmar, Lauren E Griffith, Andrea Gruneir
{"title":"Characterizing complex care relationships in Canada using the Canadian Longitudinal Study on Aging (CLSA).","authors":"Janaia Utas, Tasmin Adel, Charlotte Jensen, Stephanie A Chamberlain, Jennifer Baumbusch, Sharon Anderson, Jasneet Parmar, Lauren E Griffith, Andrea Gruneir","doi":"10.1186/s12877-025-05972-z","DOIUrl":"https://doi.org/10.1186/s12877-025-05972-z","url":null,"abstract":"<p><strong>Introduction: </strong>Most caregiving research and policy has focused on dyadic, unidirectional relationships with one caregiver and one care receiver despite evidence for more complex caring relationships.</p><p><strong>Objective: </strong>To describe caregivers and care receivers' relationships, with a focus on non-dyadic relationships, using baseline data from the Canadian Longitudinal Study on Aging (CLSA).</p><p><strong>Methods: </strong>In this cross-sectional study, we analyzed unweighted baseline CLSA data to describe different self-reported care relationships. Care relationships of interest included: a) spousal reciprocal relationships, b) care chains, where one person receives and gives care with separate individuals, c) care caravans, where one person receives care from multiple caregivers, and d) compound caregivers, where one person provides care to multiple care receivers. We estimated frequencies for categorical variables, and either means and standard deviations or medians and interquartile ranges for continuous variables.</p><p><strong>Results: </strong>Our sample included 51,338 CLSA participants. Of these respondents, 39% identified as a caregiver (mean age 62, 54% women), 6.5% identified as a care receiver (mean age 65, 58% women), and 5.3% identified as both a caregiver and care receiver (mean age 63, 65% women). Our research showed that 40% of caregivers reported giving care to 2 or more receivers and 52% of care receivers reported receiving care from 2 or more caregivers. Individuals both receiving and giving care demonstrated the following relationships: compound care chains (73%), care chains (19%), and reciprocal spousal care (4.6%). Gender characterization showed women had a wider range of care partners and were more likely to identify as caregivers and care receivers. While spouse and first degree relatives were the most commonly reported caregivers, friends and others were a large proportion of reported caregivers.</p><p><strong>Conclusion: </strong>We found that a large proportion of caregiving relationships were best described as a network that frequently included multiple caregivers, multiple care receivers, and some in both roles, as well as non-kin and extended relative participants. This characterization of care relationships allows us to better understand the needs of older adults and their caregivers as the population ages and care shifts towards aging-in-place strategies.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"320"},"PeriodicalIF":3.4,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Splenic and portal venous flow associated with frailty and sarcopenia in older outpatients with cardiovascular disease.","authors":"Joji Ishikawa, Shutaro Futami, Ayumi Toba, Aya Yamamoto, Keisho Kobayashi, Kana Takani, Hideko Ono, Teppei Maeda, Masuyo Kawano, Masaru Kiyomizu, Yoshiaki Tamura, Atsushi Araki, Hideaki Mori, Kazumasa Harada","doi":"10.1186/s12877-025-05973-y","DOIUrl":"https://doi.org/10.1186/s12877-025-05973-y","url":null,"abstract":"<p><strong>Background: </strong>Older patients with cardiovascular disease often experience frailty and sarcopenia. We evaluated whether a reduced blood flow in the splenic and portal vein is associated with frailty and sarcopenia in older patients with cardiovascular disease.</p><p><strong>Methods: </strong>Blood flow in the splenic and portal vein was evaluated using EPIQ7 (Philips) in older patients (aged ≥ 65 years, 123 patients) with cardiovascular disease, who visited the frailty outpatient clinic. Frailty was assessed using the Japanese version of Cardiovascular Health Study (J-CHS) criteria and the Kihon Checklist (KCL), while sarcopenia was assessed using the Asian Working Group of Sarcopenia 2019 criteria.</p><p><strong>Results: </strong>The mean age of the patients was 81.6 ± 6.6 years (42.3% female). Frailty was observed in 34.2% of patients using the J-CHS criteria and 36.9% using the KCL criteria, while severe sarcopenia was identified in 20.2% of patients. In the KCL criteria, the splenic venous flow decreased with the severity of frailty (248.3 ± 148.4, 202.1 ± 177.9, 139.2 ± 81.1 mL/min, P = 0.007), Additionally, the splenic venous flow was significantly lower in frail patients than in robust patients (P = 0.006). This association remained significant even after adjusting for confounding factors such as age, sex, body mass index, habitual drinking, smoking history, diabetes, dyslipidemia, hypertension, systolic blood pressure, atrial fibrillation, heart failure, and history of stroke (P = 0.039). In a parallel analysis, the splenic venous flow was remarkably decreased in patients with sarcopenia (232.0 ± 172.8 vs. 145.0 ± 91.9 mL/min, P = 0.003); however, no significant relationship was found between the severity of frailty and splenic venous flow according to the J-CHS criteria (P = 0.159). Among the J-CHS criteria sub-items, the splenic venous flow was decreased in patients with a decreased appendicular skeletal muscle index (ASMI) (332.9 ± 41.6 vs. 98.5 ± 43.5 mL/min, P = 0.005); however, there was no significant difference in the splenic venous flow between patients with and without decreased walking speed (P = 0.064) or reduced grip strength (P = 0.369). The portal venous flow was not significantly associated with frailty or sarcopenia.</p><p><strong>Conclusion: </strong>In older patients with cardiovascular disease, a decreased splenic venous flow was observed in those with frailty by the KCL criteria, those with sarcopenia, and those with a decreased ASMI.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"319"},"PeriodicalIF":3.4,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC GeriatricsPub Date : 2025-05-09DOI: 10.1186/s12877-025-05982-x
Mana Shiotani, Yuki Hyohdoh, Yutaka Hatakeyama, Hiroaki Kazui, Yoshiyasu Okuhara
{"title":"Identifying suppressive factors of Alzheimer's disease through comprehensive analysis of real-world data: a single-center retrospective study.","authors":"Mana Shiotani, Yuki Hyohdoh, Yutaka Hatakeyama, Hiroaki Kazui, Yoshiyasu Okuhara","doi":"10.1186/s12877-025-05982-x","DOIUrl":"https://doi.org/10.1186/s12877-025-05982-x","url":null,"abstract":"<p><strong>Background: </strong>In addition to conventional symptomatic treatment drugs, anti-amyloid beta antibody drugs are expected to benefit patients with Alzheimer's disease (AD). However, issues such as side effects and high costs persist, and new preventive and therapeutic drugs are desired. Meanwhile, information on the diagnosis and symptomatic treatment of AD accumulated during daily clinical practice is stored as real-world data and is considered a powerful means of discovering unknown factors that could provide clues for new prevention and treatment approaches for AD through comprehensive exploration.</p><p><strong>Methods: </strong>We used anonymized hospital information system data from a tertiary care and academic hospital in Japan, spanning from 1981 to 2016, to search for potential suppressive factors for AD onset and to verify the validity of the discovered factors. We initially conducted a comprehensive search for candidate suppressive factors for AD and verified them using the inverse probability weighting (IPW) method with propensity scores.</p><p><strong>Results: </strong>From the comprehensive search, we identified glycyrrhizic acid (GA), a component of licorice, a traditional medicine with anti-inflammatory, antioxidant, antibacterial, and antiaging properties, as a candidate suppressing factor for AD. The IPW method showed that the odds ratio of developing AD in the GA group was 0.642 (95% confidence interval: 0.566-0.727) compared with the non-GA group after adjustment.</p><p><strong>Conclusions: </strong>This is the first human study to suggest that GA may be a factor that can suppress the onset of AD. Additionally, our method could be a promising tool for drug repositioning that applies existing drugs already used in clinical settings with well-known side effects to diseases different from their original use.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"321"},"PeriodicalIF":3.4,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC GeriatricsPub Date : 2025-05-08DOI: 10.1186/s12877-025-05987-6
Synneve Dahlin-Ivanoff, Frida Mjörnstedt Oleander, Katarina Wilhelmson
{"title":"Improving comprehensive geriatric assessments with the clinical frailty scale: a focus group study.","authors":"Synneve Dahlin-Ivanoff, Frida Mjörnstedt Oleander, Katarina Wilhelmson","doi":"10.1186/s12877-025-05987-6","DOIUrl":"https://doi.org/10.1186/s12877-025-05987-6","url":null,"abstract":"<p><strong>Background: </strong>The purpose of this study is to exploratively evaluate the geriatric team's views on the implementation of the Comprehensive Geriatric Assessment (CGA) and Clinical Frailty Scale (CFS) on frail older people with acute orthopaedic disorders who are cared for in two geriatric care wards in the southwest of Sweden.</p><p><strong>Methods: </strong>A qualitative design with focus groups was applied, based on a social constructivist research tradition. This approach differs from other qualitative methods, such as interviews, in that it encourages interaction between research participants and contributes to shedding light on a collective understanding of the world. This means that the analysis is based on the group's collective input, not individual statements. The study group consisted of 21 professionals participating in four focus groups, with five to six participants per group. The participants in each group represented different professions within the geriatric team, including nurses, nursing assistants, physicians, occupational therapists, and physiotherapists.</p><p><strong>Results: </strong>The results underscore the importance of the CFS as the basis for CGA, emphasizing the effectiveness of the scale as a shared instrument promoting collaboration in healthcare. Our study uniquely points out the lack of research exploring the team-based use of tools for conducting a frailty assessment using the CFS. The study also highlights the importance of effective teamwork and a person-centred approach. The balance between person-centred care and what is feasible within the organization is crucial to providing the best possible care for patients.</p><p><strong>Conclusions: </strong>In Sweden, as in other places, how healthcare staff experience their work is key to the quality of care. The study concludes that positive staff experiences with new approaches drive healthcare improvement, benefiting patients and society. This highlights the potential for further improvements in healthcare delivery through continued innovation and collaboration.</p><p><strong>Trial registration: </strong>Clinical trial number: not applicable.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"317"},"PeriodicalIF":3.4,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12060463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between life satisfaction, sleep disturbance and mental health problems among the migrant older adults with children: a conditional process analysis based on per capita bedroom area.","authors":"Mingli Pang, Jieru Wang, Hexian Li, Guangwen Liu, Xiaoxu Jiang, Jing Xu, Shixue Li, Fanlei Kong","doi":"10.1186/s12877-025-05957-y","DOIUrl":"https://doi.org/10.1186/s12877-025-05957-y","url":null,"abstract":"<p><strong>Background: </strong>The relationship between life satisfaction and mental health problems had been confirmed in many existed studies, but the underlying mediating and moderating effect of sleep disturbance and per capita bedroom area (PCBA) behind this association had never been identified. This study aimed to explore the mediating role of sleep disturbance and the moderating effect of PCBA on the association between life satisfaction and mental health problems.</p><p><strong>Methods: </strong>Multistage cluster random sampling method was used to select the participants and finally 613 migrant older adults with children (MOAC) were included in the survey. A conditional process model was performed to examine the relationship between life satisfaction and mental health problems, as well as the mediating effect of sleep disturbance and the moderating effect of PCBA.</p><p><strong>Results: </strong>Life satisfaction was negatively associated with mental health problems, and sleep disturbance could mediate their association. Furthermore, the direct effect of life satisfaction on mental health problems and the indirect effect of sleep disturbance in the relationship were moderated by PCBA, but it only moderated the direct effect and the second indirect link (sleep disturbance-mental health problems) of the mediating effect. Both these two effects were stronger for MOAC with a low level of PCBA.</p><p><strong>Conclusions: </strong>Life satisfaction had negative effect on mental health problems. PCBA moderated the direct effect of life satisfaction on mental health problems and the mediating effect of sleep disturbance on mental health problems. For MOAC with a low level of life satisfaction and high sleep disturbance, particularly those with a low level of PCBA, targeted implication for the community, family members and MOAC were proposed to improve the mental health of MOAC.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"318"},"PeriodicalIF":3.4,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12060403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}