BMC Geriatrics最新文献

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The prevalence and etiology of anemia and the association between anemia and all-cause mortality: a cohort study over a 9-year period. 贫血的患病率和病因学以及贫血与全因死亡率之间的关系:一项为期9年的队列研究。
IF 3.8 2区 医学
BMC Geriatrics Pub Date : 2025-09-26 DOI: 10.1186/s12877-025-06353-2
Yazhi Yang, Hurong Lai, Caifeng Liao, Huijun Chen, Xiaoyan Jiang, Chuyang Lin, Ling He, Huaijun Tu, Jian Li
{"title":"The prevalence and etiology of anemia and the association between anemia and all-cause mortality: a cohort study over a 9-year period.","authors":"Yazhi Yang, Hurong Lai, Caifeng Liao, Huijun Chen, Xiaoyan Jiang, Chuyang Lin, Ling He, Huaijun Tu, Jian Li","doi":"10.1186/s12877-025-06353-2","DOIUrl":"10.1186/s12877-025-06353-2","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"707"},"PeriodicalIF":3.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12465429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145173428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trust and cognitive function: a population-based cross-sectional survey among older adults relocated for poverty alleviation in Shanxi, China. 信任与认知功能:一项基于人口的横断面调查:在中国山西扶贫搬迁的老年人。
IF 3.8 2区 医学
BMC Geriatrics Pub Date : 2025-09-26 DOI: 10.1186/s12877-025-06375-w
Le Yang, Jing Wang, Dan Guo, Xin Zhang, Ling Wang
{"title":"Trust and cognitive function: a population-based cross-sectional survey among older adults relocated for poverty alleviation in Shanxi, China.","authors":"Le Yang, Jing Wang, Dan Guo, Xin Zhang, Ling Wang","doi":"10.1186/s12877-025-06375-w","DOIUrl":"10.1186/s12877-025-06375-w","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated the association between generalized/particularized trust and cognitive function, with a focus on sex differences, among Chinese older adults relocated for poverty alleviation.</p><p><strong>Methods: </strong>In 2023, a total of 1882 relocated older adults (≥ 60) were surveyed by using a multi-stage stratified sampling method in Shanxi province, China, under a cross-sectional study design. Trust was assessed in generalized trust (i.e. generalized trust in society and in community) and particularized trust (i.e. particularized trust in family, friends, neighbours, and authoritative identity). Older adults' cognitive function was measured by the Chinese version of Mini-Mental State Examination (CMMSE). Hierarchical linear regression was performed to determine the association between trust and cognitive function.</p><p><strong>Results: </strong>Particularized trust in friends and particularized trust in authoritative identity were positively associated with cognitive function in the full sample. After controlling all confounders (i.e. demographic and socioeconomic characteristics, health behaviors and health status, and relocation characteristics), older adults who trusted in friends (β = 0.08, 95% CI: 0.23;1.94, P < 0.05) and who trusted in community/village staff (β = 0.08, 95% CI: 0.26;1.69, P < 0.01) reported better cognitive function. Generalized trust in society was negatively associated with cognitive function, older men who trusted most people showed lower cognitive function (β=-0.14, 95%CI: -2.67;-0.82, P < 0.001), and the comparison of the regression coefficients between the male and female were significantly different using suest test (P < 0.01). Particularized trust in friends and authoritative identity was positively associated with the cognitive function of relocated older men. However, the association between trust and cognitive function was not found among relocated older women.</p><p><strong>Conclusions: </strong>Trust is associated with the cognitive function of older adults relocated for poverty alleviation in China, future policy interventions must highlight relocated older adults who have low trust in friends and community/village staff, more attention needs to be paid to the tailored interventions of trust promotion to different sexes.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"729"},"PeriodicalIF":3.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12465411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145173484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between financial social support and functional disability among older adults: analysis of the ELSI-Brazil. 经济社会支持与老年人功能障碍之间的关系:elsi -巴西的分析。
IF 3.8 2区 医学
BMC Geriatrics Pub Date : 2025-09-26 DOI: 10.1186/s12877-025-05845-5
Bruna Venturin, Andressa Souza Cardoso, María Del PilarFlores-Quispe, Franciéle Marabotti Costa Leite, Elaine Thumé, Fabíola Bof de Andrade, Maria Fernanda Furtado de Lima Costa, Luiz Augusto Facchini
{"title":"Association between financial social support and functional disability among older adults: analysis of the ELSI-Brazil.","authors":"Bruna Venturin, Andressa Souza Cardoso, María Del PilarFlores-Quispe, Franciéle Marabotti Costa Leite, Elaine Thumé, Fabíola Bof de Andrade, Maria Fernanda Furtado de Lima Costa, Luiz Augusto Facchini","doi":"10.1186/s12877-025-05845-5","DOIUrl":"10.1186/s12877-025-05845-5","url":null,"abstract":"<p><strong>Background: </strong>Population aging requires attention. The increase in the number of older adults, accompanied by the growth of functional disabilities, can impact the social and economic adjustments of the individual, family, and communities, resulting in the need for financial support to meet the demands generated by these disabilities. The association between receiving financial support and the inability to carry out activities in quantitative studies is rarely reported in the literature. This investigation aims to estimate the occurrence of financial social support and its association with functional disability among older adults aged 60 years or older residing in urban areas of Brazil.</p><p><strong>Method: </strong>A cross-sectional analysis of a population-based longitudinal study conducted in Brazil with a baseline in 2015/16 and follow-up in 2019/20 was performed. The dependent variable of interest was financial support. The Katz and Lawton & Brody scales were used to measure functional disability to perform basic (BADL) and instrumental (IADL) activities of daily living, respectively. The association between financial support and functional disability for BADL and IADL was tested using logistic regression, expressed as Odds Ratio (OR) and 95% confidence intervals (95% CI).</p><p><strong>Results: </strong>The frequency of receiving financial support among older adults was 13.8% (2015; CI95% 12.6-15.0) and 11.3% (2019; CI95% 9.7-13.1). Receiving financial support was significantly associated with functional disability in both BADL and IADL. After adjustments, older adults with functional disability in BADL were 1.35 (CI95% 1.01-1.81) and 1.75 (CI95% 1.25-2.44) times more likely to receive financial support in 2015 and 2019, respectively. Older adults with a disability to perform IADL were 1.53 and 1.42 times more likely to receive support compared to older adults without disabilities, after adjusting for confounders factors (OR 2015: 1.53; CI95% 1.22-1.92; OR 2019: 1.42; CI95% 1.10-1.83).</p><p><strong>Conclusions: </strong>The receipt of financial support is greater among older adults with basic and instrumental functional disabilities. The association identified highlights the importance of public policies aimed at improving socioeconomic conditions and quality of life for older adults.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"720"},"PeriodicalIF":3.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12466034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145173286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"Why do i have to get naked to have a sandwich made?": The social problem of aging and cultural shift needed to facilitate aging in place. “为什么我要脱光衣服才能做三明治?”老龄化的社会问题和文化转变需要促进老龄化到位。
IF 3.8 2区 医学
BMC Geriatrics Pub Date : 2025-09-26 DOI: 10.1186/s12877-025-06199-8
Danielle Jacobson, Tashani Parker, Junhee Baek, Lauren Cadel, Walter P Wodchis, Elizabeth Mansfield, Laura Rosella, Marissa Bird, Kerry Kuluski
{"title":"\"Why do i have to get naked to have a sandwich made?\": The social problem of aging and cultural shift needed to facilitate aging in place.","authors":"Danielle Jacobson, Tashani Parker, Junhee Baek, Lauren Cadel, Walter P Wodchis, Elizabeth Mansfield, Laura Rosella, Marissa Bird, Kerry Kuluski","doi":"10.1186/s12877-025-06199-8","DOIUrl":"10.1186/s12877-025-06199-8","url":null,"abstract":"<p><strong>Background: </strong>Over the next 2 decades, the population of older adults (65 years of age and up) in Canada is anticipated to rise significantly, with the most rapidly increasing subset being racialized minorities. Many older adults prefer to age at home and in the community despite lacking services to support this goal. Considering older adults' growth rate and preferences, the research team sought to investigate what resources were needed to facilitate aging in place.</p><p><strong>Methods: </strong>This study took place in Peel Region (Ontario, Canada), a particularly diverse region in Canada. 15 focus groups and 7 1-on-1 interviews were conducted with 42 participants (14 older adults, 10 caregivers, 18 healthcare providers). Each session included 2 parts: (1) co-designing a persona, and (2) co-designing a care package for the persona based on what they would need to age at home. A collaborative approach was taken to Braun and Clarke's inductive thematic analysis.</p><p><strong>Findings: </strong>Overall, participants pointed to the social problem and medicalization of aging and discussed a broader cultural shift necessary to facilitate aging in place. This cultural shift was multifaceted and involved reducing fear-based health education rooted in liability concerns, caregivers and families accepting risks, a better balance between governmental responsibility and community sustainability, and looking to other optimal models of care (e.g., palliative care model, family planning model for advanced care planning). Important to shifting the culture of care was also the need to better balance standardized and personalized care. Older adults and caregivers needed opportunity to voice their needs. When older adults did not receive flexible accommodations for their specific circumstances, there were often spillover costs. Finally, important to centering older adults and caregivers in person-centred care provision was a needed shift in the consistency and reliability of care services that supported older adults to age in place.</p><p><strong>Conclusions: </strong>Participants described receiving care that was often not person- and family-centered despite this being a purported healthcare system value in Ontario, Canada. A cultural shift is thus needed in medical and social expectations of what it means to care for older adults.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"725"},"PeriodicalIF":3.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12465727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145172394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adiponectin pathway regulates cerebral metabolic dysfunction and neuroinflammation via the AdipoR1/PI3K/Akt axis in Perioperative Neurocognitive Disorder. 脂联素通路通过AdipoR1/PI3K/Akt轴调控围手术期神经认知障碍的脑代谢功能障碍和神经炎症。
IF 3.8 2区 医学
BMC Geriatrics Pub Date : 2025-09-26 DOI: 10.1186/s12877-025-06367-w
Zhijing Zhang, Chengyuan Hu, Binbin Li, Chengzhi Zhong, Lideng Guo, Baiqin Su, Huiqun Chen, Haihui Xie
{"title":"Adiponectin pathway regulates cerebral metabolic dysfunction and neuroinflammation via the AdipoR1/PI3K/Akt axis in Perioperative Neurocognitive Disorder.","authors":"Zhijing Zhang, Chengyuan Hu, Binbin Li, Chengzhi Zhong, Lideng Guo, Baiqin Su, Huiqun Chen, Haihui Xie","doi":"10.1186/s12877-025-06367-w","DOIUrl":"10.1186/s12877-025-06367-w","url":null,"abstract":"<p><strong>Backgroud: </strong>Perioperative neurocognitive disorder (PND) is a prevalent and serious complication in elderly surgical patients, with limited effective therapeutic options available. While our prior research has demonstrated the neuroprotective potential of the adiponectin pathway in PND, the underlying mechanisms remain to be fully elucidated.</p><p><strong>Methods: </strong>In a prospective cohort study, we collected serum, cerebrospinal fluid (CSF), and sociodemographic data from 41 elderly hip fracture patients (29 normal and 12 PND patients). Further, twelve-month-old male Sprague-Dawley rats were divided into sham, PND (splenectomy), and PND + Adiporon (APN, 50 mg/kg/day intragastrically) group. Lactate, pyruvate, TNF-α and IL-1β levels in CSF and hippocampus were measured. Additionally, a PND + APN + LY294002 (a PI3K inhibitor, 25 mg/kg/day intraperitoneally) group was established to explore the underlying mechanisms further. Cognitive function was assessed using the Morris Water Maze (MWM) test. Glucose transport (Glut) 1, glycolysis (HK2, PFKFB3 and PKM2), energy production (ATP and Na<sup>+</sup>/K<sup>+</sup>-ATPase), microglia-mediated neuroinflammation (Iba1, TNF-α, IL-1β) and synaptic protein (PSD95, SYP and SYN I) were assessed in hippocampus.</p><p><strong>Results: </strong>PND elderly patients exhibited lower serum adiponectin levels, which correlated with higher lactate/pyruvate ratio (Pearson's r correlation: -0.4513; p = 0.0031) and higher TNF-α level (Pearson's r correlation: -0.4311; p = 0.0049) in CSF. In PND rats, APN reduced lactate, lactate/pyruvate ratio, TNF-α, and IL-1β in brain. Mechanistically, APN activated AdipoR1-dependent PI3K/Akt signaling, enhanced Glut1 membrane localization, HK2 activity, and Na<sup>+</sup>/K<sup>+</sup>-ATPase activity. APN also inhibited microglia overactivation and neuroinflammation. Activation of the adiponectin pathway improved cognitive performance in the MWM test.</p><p><strong>Conclusion: </strong>The adiponectin pathway regulates cerebral metabolic dysfunction and neuroinflammation via the AdipoR1/PI3K/Akt axis, which serves as a potential therapeutic target for improving perioperative cognitive outcomes in elderly patients.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"721"},"PeriodicalIF":3.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12465995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145172925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The mediating effect of perceived social support between e-health literacy and self-management ability in elderly stroke patients: a cross-sectional survey. 感知社会支持在老年脑卒中患者电子健康素养与自我管理能力之间的中介作用:一项横断面调查。
IF 3.8 2区 医学
BMC Geriatrics Pub Date : 2025-09-26 DOI: 10.1186/s12877-025-06369-8
Taotao He, Jing Huang, Caini Song, Conghui Du, Wenxia Zhang, Qunli Zhu, Hongmei Shi
{"title":"The mediating effect of perceived social support between e-health literacy and self-management ability in elderly stroke patients: a cross-sectional survey.","authors":"Taotao He, Jing Huang, Caini Song, Conghui Du, Wenxia Zhang, Qunli Zhu, Hongmei Shi","doi":"10.1186/s12877-025-06369-8","DOIUrl":"10.1186/s12877-025-06369-8","url":null,"abstract":"<p><strong>Background: </strong>Self-management significantly affects the physical and mental recovery of elderly stroke patients and can improve their quality of life. This study aims to describe the current status and investigate the correlations of e-health literacy, self-management abilities, and perceived social support among elderly stroke patients. Furthermore, it explores the mediating effect of perceived social support on the relationship between e-health literacy and self-management abilities in elderly stroke patients.</p><p><strong>Methods: </strong>337 elderly stroke patients from four tertiary hospitals in Hunan Province were recruited via convenience sampling and completed a demographic questionnaire, the eHealth Literacy Scale, the Perceived Social Support Scale, and the Stroke Self-Management Ability Scale, between March and May 2024. Statistical analyses were conducted using independent samples t-test, one-way analysis of variance, Pearson correlation analysis, and the Bootstrap method.</p><p><strong>Results: </strong>The total scores for eHealth literacy, self-management ability, and perceived social support among elderly stroke patients were 17.43 ± 8.11, 87.76 ± 13.39, and 55.33 ± 12.09, respectively. The three variables were positively correlated (P < 0.05), and perceived social support partially mediated the relationship between eHealth literacy and self-management ability in elderly stroke patients, accounting for 49.02% of the total effect.</p><p><strong>Conclusions: </strong>In elderly stroke patients, e-health literacy is low, self-management ability is medium, and perceived social support serves as a partial mediator between them. It was suggested that medical staff focus on the social support system of elderly stroke patients, increase their use of social support, and then improve their e-health literacy for the purpose to provide a solid foundation for promoting their self-management of the disease and enhancing their quality of life.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"712"},"PeriodicalIF":3.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12465189/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145173467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization and factors influencing the uncertainty of intolerable in older adults with multimorbidity: A Cross-sectional study. 一项横断面研究:多病老年人不能忍受不确定性的特征和影响因素。
IF 3.8 2区 医学
BMC Geriatrics Pub Date : 2025-09-25 DOI: 10.1186/s12877-025-06363-0
Hao Tie, Jingru Zhang
{"title":"Characterization and factors influencing the uncertainty of intolerable in older adults with multimorbidity: A Cross-sectional study.","authors":"Hao Tie, Jingru Zhang","doi":"10.1186/s12877-025-06363-0","DOIUrl":"10.1186/s12877-025-06363-0","url":null,"abstract":"<p><strong>Background: </strong>Multiple co-morbidities of chronic diseases tend to increase patients' medical costs and psychological stress, and reduce their quality of life. However, few studies have examined the mental health of older adults from cognitive perspectives and chronic disease co-morbidities.</p><p><strong>Objectives: </strong>The aim is to investigate the current status of intolerable uncertainty and the factors that influence it in elderly patients with chronic comorbidities.</p><p><strong>Design: </strong>Cross-sectional study design.</p><p><strong>Settings: </strong>Departments of Gastroenterology, Endocrinology, Cardiovascular Medicine, and Respiratory Medicine, a tertiary hospital in Henan Province, China.</p><p><strong>Participants: </strong>Elderly patients with chronic co-morbidities hospitalized in the departments of gastroenterology, endocrinology, cardiovascular medicine and respiratory medicine.</p><p><strong>Methods: </strong>A non-probability convenient sampling method was used to select 295 elderly chronic disease co-morbid patients who were hospitalized in a tertiary-level hospital in Henan Province from June 2023 to December 2023, and general information questionnaires, the short version of the Intolerable Uncertainty Scale (IUS-12), the Family Caringness Rating Scale (APGAR), and World Health Organization Five Physical and mental health indicators (WHO-5) were used to investigate and analyze the influencing factors of intolerable uncertainty in elderly chronic disease co-morbid patients.</p><p><strong>Results: </strong>The total IUS-12 score in elderly patients with chronic disease co-morbidities was (35.58 ± 3.24), the total APGAR score was (7.27 ± 2.29), and the total WHO-5 score was (17.37 ± 2.69). The total IUS-12 score of elderly chronic disease co-morbidities was negatively correlated with the total APGAR score (r=-0.884, P<0.01) and with the total WHO-5 score (r=-0.920, P<0.01). The results of multiple linear regression showed that rural area, living alone, family care and physical and mental health were independent influences on the intolerable uncertainty of elderly chronic co-morbid patients (P < 0.05).</p><p><strong>Conclusions: </strong>The intolerable uncertainty of elderly patients with chronic disease co-morbidities is at a medium level, and clinical work should focus on the phenomenon of intolerable uncertainty of elderly patients with chronic disease co-morbidities, strengthen the early identification and nursing interventions for high-risk groups in rural areas, living alone, with low family care, and with poor physical and mental health, and give full play to the strengths of humanistic care in nursing to improve the quality of life. Urge policymakers to allocate targeted funding to underserved regions in order to expand access to specialized geriatric nursing services, telehealth infrastructure, and community-based support networks for patients living alone.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"706"},"PeriodicalIF":3.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12465699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145147715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of the QT interval prolongation and its risk factors in hospitalized geriatric patients: findings of a single center cross-sectional study in Pakistan. 住院老年患者QT间期延长的患病率及其危险因素:巴基斯坦单中心横断面研究的结果
IF 3.8 2区 医学
BMC Geriatrics Pub Date : 2025-09-25 DOI: 10.1186/s12877-025-06418-2
Huma Tanveer, Muhammad Ashfaq, Muhammad Junaid Hassan Sharif, Muhammad Mamoon Iqbal, Ayesha Iqbal, Qasim Khan, Muhammad Zeeshan Haroon, Adel Bashatah, Wajid Syed, Naji Alqahtani
{"title":"Prevalence of the QT interval prolongation and its risk factors in hospitalized geriatric patients: findings of a single center cross-sectional study in Pakistan.","authors":"Huma Tanveer, Muhammad Ashfaq, Muhammad Junaid Hassan Sharif, Muhammad Mamoon Iqbal, Ayesha Iqbal, Qasim Khan, Muhammad Zeeshan Haroon, Adel Bashatah, Wajid Syed, Naji Alqahtani","doi":"10.1186/s12877-025-06418-2","DOIUrl":"10.1186/s12877-025-06418-2","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"705"},"PeriodicalIF":3.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12465303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145147642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation context, mechanisms and outcomes of a transitional care intervention to prevent delirium: a mixed-methods process evaluation from the TRADE study. 预防谵妄的过渡性护理干预的实施背景、机制和结果:来自TRADE研究的混合方法过程评估。
IF 3.8 2区 医学
BMC Geriatrics Pub Date : 2025-09-25 DOI: 10.1186/s12877-025-06331-8
Natascha-Elisabeth Denninger, Simone Brefka, Gabriele Meyer, Marlene Benkert, Dhayana Dallmeier, Michael Denkinger, Martin Müller
{"title":"Implementation context, mechanisms and outcomes of a transitional care intervention to prevent delirium: a mixed-methods process evaluation from the TRADE study.","authors":"Natascha-Elisabeth Denninger, Simone Brefka, Gabriele Meyer, Marlene Benkert, Dhayana Dallmeier, Michael Denkinger, Martin Müller","doi":"10.1186/s12877-025-06331-8","DOIUrl":"10.1186/s12877-025-06331-8","url":null,"abstract":"<p><strong>Background: </strong>While predisposing factors for delirium, like old age or surgery, are well documented, less attention has been paid to environmental factors, including hospital transfer processes and caregiver involvement in transitional care of older patients. To address this gap, we developed a pathway to optimize hospital transfer processes and actively involve caregivers in preventing delirium. This complex intervention was tested in a pilot study using a stepped-wedge design across four hospitals, accompanied by a process evaluation to explore the implementation context, mechanisms and outcomes of this intervention.</p><p><strong>Methods: </strong>A parallel convergent mixed-methods process evaluation was used. Qualitative data and quantitative data were analyzed separately and integrated using a weaving approach. Analyses were guided by Normalization Process Theory, supplemented by implementation impact ratings based on the Consolidated Framework for Implementation Research rating tool.</p><p><strong>Results: </strong>Data included 72 interviews, 2 focus groups, 82 document analyses, 14 status analyses, 424 TRADE questionnaires, 58 Normalization MeAsure Development questionnaires, and website traffic metrics. COVID-19-related constraints resulted in partial implementation of the intervention, with challenges such as limited training opportunities and restricted caregiver involvement. Healthcare professionals reported greater delirium awareness, and educational materials received positive feedback.</p><p><strong>Conclusion: </strong>The study underscores the critical role of discharge information, post-discharge support, and education for caregiver and healthcare professionals in preventing delirium. It also provides evidence of how the COVID-19 pandemic impacted standard care and the implementation of clinical interventions, emphasizing the need for adaptable processes and institutional support. Furthermore, it offers theoretical and methodological insights into conducting mixed-methods process evaluations in complex intervention research.</p><p><strong>Trial registration: </strong>German Clinical Trials Register (ID: DRKS00017828, retrospectively registered on 17.09.2019, https://drks.de/search/en/trial/DRKS00017828 ).</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"704"},"PeriodicalIF":3.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12462268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145147705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a (digital) mindfulness-informed intervention for older adults in nursing homes: description and reflection of a person-based co-design approach. 为养老院的老年人开发一种(数字)正念知情干预:描述和反映一种基于人的共同设计方法。
IF 3.8 2区 医学
BMC Geriatrics Pub Date : 2025-09-25 DOI: 10.1186/s12877-025-06223-x
Maren M Michaelsen, Jule Uhl, Luka Mindrup, Claudia Neumann, Lena Langer, Tobias Esch
{"title":"Development of a (digital) mindfulness-informed intervention for older adults in nursing homes: description and reflection of a person-based co-design approach.","authors":"Maren M Michaelsen, Jule Uhl, Luka Mindrup, Claudia Neumann, Lena Langer, Tobias Esch","doi":"10.1186/s12877-025-06223-x","DOIUrl":"10.1186/s12877-025-06223-x","url":null,"abstract":"<p><strong>Background: </strong>Mindfulness and Positive Psychology interventions have proven effective in enhancing psychosocial well-being and cognitive abilities among older adults residing in long-term care facilities. However, the implementation of health promotion measures in this population remains limited. Participatory intervention development with this target group is rare and processes of generating intervention content, format, and delivery as well as design decisions are often not well-documented. Our research aim was to use person-based co-design (PBCD) methods to facilitate the translation of meaningful stakeholder experiences into the design of an on-site and digitally delivered mindfulness-informed intervention (MII) for health promotion in nursing homes.</p><p><strong>Methods: </strong>The PBCD process involved multiple stakeholders, including the target group, their relatives, nurses and other experts from nursing homes, health insurance representatives and app developers. The iterative process comprised several key steps: theory-based selection of mind-body exercises by the project team, informal discussions with intervention experts, semi-structured interviews with the target audience (n = 3) during 12 sessions, pre-test of the exercises through an online survey with researchers (n = 15), online survey with project partners, nursing facility experts, caregivers, and the general public (n = 12). Qualitative feedback was assessed through deductive-inductive content-structuring analysis. For the digital version, the app developers created two front-end application examples, of which one was further refined based on regular feedback from the target audience and the research team.</p><p><strong>Results: </strong>MII (named silBERN) for health promotion comprising preparatory elements (welcoming, general information), 22 exercises and 13 exercise repetitions in 8 modules with a delivery plan over 8 weeks. 11 exercises were adopted and 8 exercises were excluded based on feedback from different stakeholders. User experience was incorporated in the app version. The main feedback referred to the complexity/comprehension of exercises. A resource-oriented view of the target group was implemented. The PBCD process proved valuable despite its time-intensive nature.</p><p><strong>Conclusion: </strong>Stakeholder participation has led to interventions that fit the needs of the target group. The process of engaging all stakeholders in the PBCD process can be time-consuming and intensive. Careful reflection on the development process indicates that a preliminary phase of participation was carried out. A randomized controlled trial of the silBERN intervention is required to evaluate usability and effectiveness.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"703"},"PeriodicalIF":3.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12462116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145147713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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