BMC Geriatrics最新文献

{"title":"A brief report of the economic burden and epidemiological finding of suicide attempts among the older adults in Korea from 2007 to 2021.","authors":"Seoyoon Lee, Hyung Eun Shin, Rugyeom Lee, Sooyeon Jo, Seung Cheor Lee, Hyeon-Kyoung Cheong, Yong Joo Rhee, In-Hwan Oh","doi":"10.1186/s12877-025-05793-0","DOIUrl":"10.1186/s12877-025-05793-0","url":null,"abstract":"<p><strong>Aim: </strong>Quantifying the increased personal and social losses following suicide attempts among the aging population presents a significant challenge. There is an urgent need to determine the economic burden of suicide attempts among older adults in Korea.</p><p><strong>Subjects and methods: </strong>The economic burden of suicide attempts from 2007 to 2021 was assessed using claim data from the Health Insurance Review & Assessment and Causes of Death Statistics in Korea. The analysis focused on individuals diagnosed with injuries, poisoning, and other consequences of external causes (S00-T98), intentional self-harm (X60-X84), sequelae of intentional self-harm (Y87.0), and personal history of self-harm (Z91.5). Economic impacts were analyzed by year, primary and secondary diagnoses in claim data, and Cause of Death Statistics.</p><p><strong>Results: </strong>The mean age of study participants was 72.86 years, with women accounting for 48.4% of the sample. The total cost of suicide attempts increased dramatically from $0.167 million in 2007 to $1.591 million in 2021. The most frequently observed ICD-10 codes associated with these attempts were toxic effects of substances chiefly nonmedicinal as to source (T51-T65), followed by poisoning by drugs, medicaments, and biological substances(T36-T50) for both genders. While the total number of suicidal attempts generally increased annually, there were declines noted in 2020 and 2021.</p><p><strong>Conclusion: </strong>This study informs the high level of economic costs of suicide attempts that were being neglected. By thoroughly understanding demographic characteristics, emerging trends, and cost classifications, policymakers can devise more effective strategies to prevent suicide attempts, provide timely support, and mitigate the associated economic and social burdens.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"147"},"PeriodicalIF":3.4,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143565902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Missing incidents and the risk of harm in persons living with dementia reported to the Swedish police- A nationwide retrospective registry study.","authors":"Mikael Larsson, Kristofer Årestedt, Anders Svensson, Henrik Andersson, Maria Wolmesjö","doi":"10.1186/s12877-025-05809-9","DOIUrl":"10.1186/s12877-025-05809-9","url":null,"abstract":"<p><strong>Background: </strong>The number of persons living with dementia is increasing globally, including in Sweden, and these persons are at heightened risk of going missing and coming to harm. When they do go missing, the police get involved. There is a dearth of knowledge surrounding the prevalence and outcomes of harm in these instances in many countries, including Sweden, which affects our understanding of the associated risks and necessary interventions. Therefore, the aim of this study was to describe incidents of missing people and explore factors associated with harm in persons living with dementia as reported to the Swedish Police.</p><p><strong>Methods: </strong>Data on background characteristics, the missing incidents, and police response was collected from a nationwide police registry. The missing incidents were analysed using descriptive statistics and logistic regression was used to explore factors associated with harm.</p><p><strong>Results: </strong>A total of 1,041 missing person case reports concerning persons living with dementia were identified. In 61 (6%) of these reports, the missing person was harmed. The level of harm varied from lacerations to death. Male sex, no prior missing incidents, cold season, time since last contact, delayed reporting, and prolonged duration of police search effort were significantly associated with an increased probability of harm.</p><p><strong>Conclusions: </strong>Persons living with dementia constituted a substantial proportion of all missing persons case reports submitted to the Swedish Police during the study period. Persons living with dementia were also at considerable risk of harm when missing, as even minor injuries can lead to substantial consequences. Furthermore, time was a critical factor, emerging as the strongest predictor of harm in the study. This calls for the development of collaborative routines between the police and professional caregivers caring for persons living with dementia.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"153"},"PeriodicalIF":3.4,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11883908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143565919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between nap time, nighttime sleep, and multimorbidity in Chinese older adults: a cross-sectional study.","authors":"Yanliqing Song, Lin Chen, Yue Liu","doi":"10.1186/s12877-025-05807-x","DOIUrl":"10.1186/s12877-025-05807-x","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to explore the relationship between sleep duration and multimorbidity among elderly Chinese and to determine the optimal sleep duration for preventing multimorbidity.</p><p><strong>Methods: </strong>This study is based on data from the 2020 China Health and Elderly Care Longitudinal Survey (CHARLS), which collected detailed information from 5,761elderly individuals, including demographic characteristics, sleep duration, health status, and lifestyle information. Logistic regression models were used to investigate the relationship between sleep duration and multimorbidity, and restricted cubic spline analysis was employed to analyze the dose-response relationship between sleep duration and multimorbidity.</p><p><strong>Results: </strong>After adjusting for potential confounders, a U-shaped association was found between nighttime sleep duration and the likelihood of multimorbidity among the elderly. Specifically, elderly individuals with a nighttime sleep duration of 7 h had the lowest incidence of multimorbidity. Compared to those with 6-8 h of nighttime sleep, elderly individuals with less than 6 h (OR = 1.24, 95% CI: 1.05-1.48) or more than 8 h (OR = 1.79, 95% CI: 1.37-2.34) of nighttime sleep had a 24% and 79% increased likelihood of multimorbidity, respectively. The restricted cubic spline analysis further confirmed this U-shaped relationship, showing that the likelihood of multimorbidity gradually decreased as sleep duration increased from 6 to 7 h, but gradually increased as sleep duration exceeded 7 h. Additionally, a positive correlation was found between napping habits and the likelihood of multimorbidity, with elderly individuals without napping habits having a lower likelihood of multimorbidity compared to those with napping habits. Subgroup analysis indicated no significant differences in the impact of 6-8 h of nighttime sleep on multimorbidity among male and female elderly individuals and different age groups.</p><p><strong>Conclusion: </strong>Appropriate nighttime sleep duration may be an important factor in preventing multimorbidity among the elderly, while increased napping duration may increase the likelihood of multimorbidity. These findings provide scientific evidence for sleep health management among the elderly, suggesting the promotion of appropriate sleep duration to reduce the likelihood of multimorbidity in this population.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"151"},"PeriodicalIF":3.4,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143565905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caring perception questionnaire of the home-dwelling elderly: development and validation study.","authors":"Mingjiao Feng, Lei Huang, Yuqin Chen, Yanjie You, Hongwei Chang, Lihua Zhang, Fengjian Zhang, Yilan Liu","doi":"10.1186/s12877-025-05785-0","DOIUrl":"10.1186/s12877-025-05785-0","url":null,"abstract":"<p><strong>Background: </strong>The care requirements of the elderly who live at home should receive enough attention as the world's population ages. On the basis of this, a questionnaire on the elderly who live at home must be created and validated.</p><p><strong>Objective: </strong>The objective is to create and validate a tool that will allow caregivers to more accurately measure how well-cared-for elderly people perceive them to be at home.</p><p><strong>Methods: </strong>This study developed a caring perception questionnaire through literature review and interviews in Wuhan. Fifteen experts from six provinces reviewed the initial 43-item draft. When faulty questionnaires were eliminated, the valid sample size for the exploratory factor analysis of the first survey was 238. For confirmatory factor analysis, the second survey's valid sample size was 260. The final version included 31 items, validated for reliability and validity.</p><p><strong>Results: </strong>A 52-item questionnaire was created based on interviews, refined to 43 items after expert feedback, with a content validity index of 0.88. The first survey (238 valid responses) showed a Cronbach's α of 0.945, and the second (260 valid responses) confirmed good model fit and consistency. The final version has 31 items.</p><p><strong>Conclusions: </strong>With good reliability and validity, the caring perception questionnaire of the home-dwelling elderly was developed, which could be used as a tool to evaluate the current situation of humanistic care for the home-dwelling elderly.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"146"},"PeriodicalIF":3.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adaptation and validation of the modified Egyptian Arabic version of Addenbrooke's Cognitive Examination III (VI-ACE-III) for assessing cognitive impairment in visually impaired elderly.","authors":"Samar Mamdouh Abdelsalam, Abeer Hassan Mohamed Matter, Hazem Mohamed El-Hariri, Ahmed Hassan Assaf, Mohamed Shawky Khater, Heba Mohamed Tawfik","doi":"10.1186/s12877-025-05784-1","DOIUrl":"10.1186/s12877-025-05784-1","url":null,"abstract":"<p><strong>Background: </strong>Vision impairment affects the accuracy of cognitive test outcomes, emphasizing the need for developing cognitive screening tools designed for visually impaired individuals, especially considering global aging trends. This study aimed to develop a modified, validated version of the Vision-Impairment version of Addenbrooke's Cognitive Examination III (VI-ACE-III) for Arabic-speaking elderly individuals with vision impairment in Egypt. In addition, the study aimed to assess the accuracy of VI-ACE-III in diagnosing dementia and mild cognitive impairment (MCI).</p><p><strong>Methods: </strong>The VI-ACE-III was developed using large printed formats and verbal substitution of the vision-dependent items. One hundred and eighty participants aged ≥ 60, with varying degrees of vision impairment (including moderate, severe, and blindness), were divided into three equal groups: 60 individuals with MCI, 60 with mild to moderate dementia, and 60 with cognitively intact controls. Receiver operating characteristics (ROC) curves were plotted to assess the accuracy of the test screening.</p><p><strong>Results: </strong>ROC analysis for dementia established an optimal cut-off point of 84 out of 115, demonstrating 100.0% sensitivity, 98.3% specificity, and an area under the curve (AUC) of 0.983, based on the comparison between the dementia and MCI groups. The analysis for MCI determined an optimal cut-off point of 94 out of 115, with 95.0% sensitivity, 96.7% specificity, and an AUC of 0.983 compared to controls. The VI-ACE-III demonstrated significant Cronbach's alpha values (α = 0.866, α = 0.771), indicating strong internal consistency within the dementia and MCI groups.</p><p><strong>Conclusions: </strong>The VI-ACE-III showed good sensitivity and specificity for assessing dementia and MCI in Arabic-speaking elderly individuals with visual impairment (VI) in Egypt. Regular screening and interventions are crucial for managing and preventing the deterioration of cognitive dysfunction and vision impairment in the elderly population.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"145"},"PeriodicalIF":3.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and risk factors of self-reported adverse drug events in elderly co-morbid patients in northeastern China: a cross-sectional study.","authors":"Daqiu Wang, Aiping Wang, Xin Meng, Lei Liu","doi":"10.1186/s12877-025-05732-z","DOIUrl":"10.1186/s12877-025-05732-z","url":null,"abstract":"<p><strong>Background: </strong>Older adults are vulnerable to adverse drug events given the pharmacokinetic and pharmacodynamic changes that coming with ageing, as well as they often take multiple medications for their chronic health conditions, especially older co-morbidities. ADEs can cause unnecessary emergency department visits and hospitalization, which contribute to financial burden and decreased quality of life. This study aims to investigate the prevalence of adverse drug events in elderly co-morbid patients in Liaoning province and explore its risk factors, in order to ensure medication safety in elderly patients.</p><p><strong>Methods: </strong>This was a cross-sectional study that enrolled elderly patients with co-morbidities, and the data were collected by nurses using a structured interview method for elderly patients with multimorbidity. Risk factors for patient-reported adverse drug events were identified by univariate and logistic regression analyses.</p><p><strong>Results: </strong>A total of 329 elderly patients were enrolled, among whom 169 were females, with an age ranging from 61 to 90 years. 205 participants (62.3%) had 462 \"possible-probable-certain\" adverse drug events, and 156 (47.4%) experienced two or more self-reported adverse drug events concurrently. The logistic regression analysis included four variables: female (OR = 2.194, 95% confidence interval 1.281-3.760, P = 0.004), numbers of daily drugs > 12 (OR = 2.257, 95% confidence interval 1.254-4.061, P = 0.007), history of fall within 1 year (OR = 3.106, 95% confidence interval 1.112-8.674, P = 0.031), and medication noncompliance (OR = 3.768, 95% confidence interval 1.535-9.249, P = 0.004).</p><p><strong>Conclusion: </strong>Patient-reported adverse drug events are more prevalent in older co-morbid patients in Liaoning province. Female, numbers of daily drugs, fall history with 1 year and poor medication compliance were significantly and independently associated with adverse drug events. These findings may provide informative interventions for the medication management in elderly patients living with multimorbidity.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"144"},"PeriodicalIF":3.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Living with technological challenges: does socioeconomic status affect people's health?","authors":"Jia Xu, Chun Xia, Xiuzhen Ding","doi":"10.1186/s12877-024-05662-2","DOIUrl":"10.1186/s12877-024-05662-2","url":null,"abstract":"<p><strong>Background: </strong>Technological challenges in accessing medical care services may cause individuals to feel isolated from the medical care system. This study posits that individual's subjective socioeconomic status (SES) contribute to differing levels of technological challenges when seeking medical care services, subsequently impacting their health conditions.</p><p><strong>Methods: </strong>A questionnaire survey was administered to 1,932 residents in China (1,037 men, 891 women, and 4 missing; M_age: 64.28 ± 11.30 years, range: 45-99 years). Participants included 792 urban (40.99%) and 1,140 rural (59.01%) residents. We measured SES, technological challenges perceptions, health conditions, and other control variables.</p><p><strong>Results: </strong>Analysis of 10,000 bootstrapped samples revealed that technological challenges partially mediate the association between SES and health conditions. Moreover, rural people with low SES had poorer health because of technological challenges. This effect was not significant for urban people after controlling for sex, age, education level, marital status, and experience accessing medical care services.</p><p><strong>Conclusions: </strong>SES significantly and negatively impacted individuals' health conditions, especially for rural residents, owing to their technological challenges. This study provides evidence and insights into the nexus of policy formulation, modern technology, and public perceptions regarding shortcomings and risks in public health policies.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"143"},"PeriodicalIF":3.4,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143539408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Albumin/fibrinogen ratio (AFR): a significant predictor of postoperative delirium in older patients undergoing non-neurosurgical and non-cardiac surgery.","authors":"Jiang Huo, Yuxiang Song, Jing Lu, Guijin Dou, Huixian Chen, Weidong Mi, Yingqun Yu, Yanhong Liu","doi":"10.1186/s12877-025-05714-1","DOIUrl":"10.1186/s12877-025-05714-1","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this research was to evaluate the prognostic significance of preoperative albumin to fibrinogen (AFR) for postoperative delirium (POD) in older patients with non-neurosurgical and non-cardiac surgery.</p><p><strong>Method: </strong>The retrospective cohort study included a group of patients aged 65 and above who underwent non-neurosurgical and non-cardiac surgery at the First Medical Center of Chinese PLA General Hospital from January 2014 to December 2021. AFR and POD correlation was evaluated through univariate and multivariable logistic regression analysis, as well as propensity score matching (PSM) and subgroup analysis.</p><p><strong>Results: </strong>In our study, the occurrence of POD was 2.9% (1566/53,609), with the AFR threshold identified as 10.625 based on the ROC curve. The study identified AFR ≤ 10.625 as a significant predictor of POD in both univariate and multivariable regression analyses, and the odds ratios (OR) were 2.65 (2.40-2.93), 1.98 (1.79-2.21), 1.51 (1.34-1.70), 1.27 (1.13-1.43) and 1.32 (1.14-1.53) in four models and the PSM model.</p><p><strong>Conclusion: </strong>AFR is a valuable predictor for predicting the development of POD in older patients receiving non-neurosurgical and non-cardiac procedures. This finding highlights the importance of preoperative assessment of AFR in these patients to better predict and manage the risk of POD.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"142"},"PeriodicalIF":3.4,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deprescribing psychoactive drugs in older orthogeriatric patients: findings from the GIOG2.0 Italian survey.","authors":"Andrea Cavalli, Antonio De Vincentis, Claudio Pedone, Alice Laudisio, Lucrezia Santoro, Maria Cristina Ferrara, Caterina Trevisan, Elena Tassistro, Maria Grazia Valsecchi, Giuseppe Castoldi, Chiara Mussi, Giuseppe Sergi, Andrea Ungar, Stefano Volpato, Rocco Papalia, Raffaele Antonelli Incalzi, Giuseppe Bellelli","doi":"10.1186/s12877-025-05695-1","DOIUrl":"10.1186/s12877-025-05695-1","url":null,"abstract":"<p><strong>Background: </strong>Psychoactive drugs represent a major contributor to falls in older people. This study aims to evaluate the prescribing practice of psychoactive drugs in older people hospitalized for hip fracture (HF) and to explore independent correlates of deprescribing.</p><p><strong>Methods: </strong>Multicenter prospective observational study including patients with HF admitted to 13 Orthogeriatric wards of the Italian Group of Orthogeriatrics (July 2019-August 2022). Patients underwent a comprehensive geriatric assessment. The use of psychoactive drugs associated with a higher risk of falls was assessed using a dedicated checklist. Deprescribing was defined as any reduction in the number of psychoactive drugs upon discharge, and independent correlates of deprescribing were explored using logistic regression analyses. Cluster analysis by Partitioning around Medoids was also performed in the hypothesis that selected clusters of characteristics could be associated with deprescribing.</p><p><strong>Results: </strong>One thousand eight hundred fifty-four older individuals (mean age 84 years, 77% females) were studied; 1190 (64%) were not prescribed any psychoactive drug, while 474 (26%), 129 (7%), and 61 (3%) took 1, 2, 3 or more psychoactive drugs, respectively. Among 664 patients on psychoactive drugs on admission, 177 (27%) had fewer prescriptions at discharge, mainly anxiolytics from 89 to 10 (50-6%), antipsychotics from 49 to 12 (28-7%) and antidepressants from 98 to 28 (55-16%). On the other count, 51 (8%) were prescribed more psychoactive drugs, mostly antidepressants from 25 to 45 (49-88%) and antipsychotics from 7 to 17 (14-17%). Functional autonomy (ADL aOR 0.87 [95%CI 0.78-0.97] p < 0.001), polipharmacy (aOR 1.15 [95%CI 1.03-1.29] p < 0.001) and the occurrence of post-operative delirium (aOR 1.71 [95%CI 1.09-2.66] p < 0.017) were independent correlates of deprescribing. More specifically, the clustering procedure could not improve the characterization of deprescribing; conversely, the deprescribing propensity significantly depended upon the center-specific prescriptive practice, not explained by other clinical-epidemiological factors.</p><p><strong>Conclusion: </strong>Only a small proportion of patients hospitalized for HF undergoes deprescribing of psychoactive drugs, with considerable heterogeneity among centers, suggesting that the physician's attitude rather than patient-related factors affects deprescribing.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"138"},"PeriodicalIF":3.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11871694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frailty and loneliness among community-dwelling older adults: examining reciprocal associations within a measurement burst design.","authors":"Anna Schultz, Hannes Mayerl, Wolfgang Freidl, Erwin Stolz","doi":"10.1186/s12877-025-05808-w","DOIUrl":"10.1186/s12877-025-05808-w","url":null,"abstract":"<p><strong>Background: </strong>Previous research indicates that frailty and loneliness are interrelated. The aim of this study is to analyze their possible reciprocal relationship while disentangling between- and within-person effects. The separation of these sources of variance is vital for a better understanding of potential causal mechanisms.</p><p><strong>Methods: </strong>Within the FRequent health Assessment In Later life (FRAIL70+) project, participants aged 70 and over completed two measurement bursts spread one year apart with seven biweekly assessments each. The final sample consisted of 426 individuals at baseline (M_age=77.0; SD = 5.4; 64.6% female). A latent curve model with structured residuals was used to examine the potential reciprocal relationship between frailty (37-item deficit accumulation approach) and loneliness (3-item UCLA scale).</p><p><strong>Results: </strong>No relevant cross-lagged effects over repeated 2-week periods were found between frailty and loneliness at the within-person level, but increases in frailty co-occurred with increases in loneliness. At the between-person level, higher levels of frailty correlated with higher levels of loneliness in each burst.</p><p><strong>Conclusion: </strong>The findings do not support the assumption that frailty and loneliness share a causal reciprocal relationship over weeks and months. Nonetheless, higher levels of frailty were weakly associated with higher levels of loneliness at the within- and considerably associated at the between-person level, which may indicate a common source of both domains.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"139"},"PeriodicalIF":3.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11872317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}