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Study on the current status and influencing factors of physical activity in pre-frail rural empty-nest older adults. 农村空巢老人体弱前期体力活动现状及影响因素研究
IF 3.4 2区 医学
BMC Geriatrics Pub Date : 2025-05-16 DOI: 10.1186/s12877-025-06018-0
Zhaoquan Jiang, Suning Shi, Qi Sun, Zhaoxu Xu, Mingyue Zhou, Xiaoyan Zhang, Tao Liu, Shixue Zhou
{"title":"Study on the current status and influencing factors of physical activity in pre-frail rural empty-nest older adults.","authors":"Zhaoquan Jiang, Suning Shi, Qi Sun, Zhaoxu Xu, Mingyue Zhou, Xiaoyan Zhang, Tao Liu, Shixue Zhou","doi":"10.1186/s12877-025-06018-0","DOIUrl":"https://doi.org/10.1186/s12877-025-06018-0","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the current status of physical activity and its influencing factors among pre-frail rural empty-nest older adults, and to provide targeted recommendations for improving the quality of life for rural empty-nest older adults.</p><p><strong>Methods: </strong>A purposive sampling method, considering convenience, was used to select participants. Between May and December 2023, a questionnaire survey was conducted among pre-frail rural empty-nest older adults in Chaoyang County, Liaoning Province. The survey included a demographic information form, a lifestyle behavior questionnaire, a nutrition risk assessment scale, and a physical activity scale for the older adults.</p><p><strong>Results: </strong>A total of 522 pre-frail older adults were included in this study. The median score for physical activity was 162.5 (109.0, 229.0), with walking (98.5%) and household physical activities (85.8%) being the predominant forms of activity. Logistic regression analysis revealed that the presence of hypertension (OR = 1.537), coronary heart disease (OR = 1.490), respiratory diseases (OR = 1.534), osteoarthritis (OR = 1.726), and malnutrition (OR = 1.637) were independent risk factors for low physical activity levels in pre-frail rural empty-nest older adults (P < 0.05).</p><p><strong>Conclusion: </strong>Physical activity levels among pre-frail rural empty-nest older adults are low, with walking and household activities being the primary forms of exercise. Community healthcare providers should enhance physical activity management for this population, conduct health education on chronic diseases, help foster healthy eating habits, and prevent the risk of malnutrition. These measures will help improve physical activity levels and potentially delay or even reverse the frailty state.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"347"},"PeriodicalIF":3.4,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparative analysis of sarcopenia screening methods in Thai people with type 2 diabetes mellitus in an outpatient setting. 泰国2型糖尿病患者骨骼肌减少症筛查方法的比较分析
IF 3.4 2区 医学
BMC Geriatrics Pub Date : 2025-05-16 DOI: 10.1186/s12877-025-06020-6
Ornpicha Laohajaroensombat, Thanapat Limpaarayakul, Nattapol Sathavarodom, Apussanee Boonyavarakul, Parinya Samakkarnthai
{"title":"A comparative analysis of sarcopenia screening methods in Thai people with type 2 diabetes mellitus in an outpatient setting.","authors":"Ornpicha Laohajaroensombat, Thanapat Limpaarayakul, Nattapol Sathavarodom, Apussanee Boonyavarakul, Parinya Samakkarnthai","doi":"10.1186/s12877-025-06020-6","DOIUrl":"https://doi.org/10.1186/s12877-025-06020-6","url":null,"abstract":"<p><strong>Background: </strong>Type 2 Diabetes Mellitus (T2DM) is closely linked with sarcopenia. The lack of validated, easy, and effective sarcopenia screening tools for people with T2DM may result in underdiagnosis, delayed interventions, and worsening outcomes. This study evaluated and compared the diagnostic accuracy of various sarcopenia screening tools in T2DM outpatients.</p><p><strong>Methodology: </strong>A cross-sectional study was conducted on 329 people with T2DM at Phramongkutklao Hospital, Thailand, between December 2023 and November 2024. This study compared eight sarcopenia screening tools. The Asian Working Group for Sarcopenia 2019 (AWGS 2019) criteria served as the reference standard. Sensitivity, Specificity, and diagnostic accuracy were evaluated using receiver operating characteristic (ROC) curve analysis. The optimal cutoffs were identified with the Youden index.</p><p><strong>Results: </strong>The prevalence of sarcopenia was 23.7%. Calf circumference showed the highest diagnostic accuracy at standard cutoff (AUC: 0.892), with optimised cutoff points of < 37.0 cm for males and < 36.0 cm for females, and achieved high sensitivity (90.1% for males, 91.1% for females) with acceptable specificity (77.2% for males, 67.8% for females). Neck circumference demonstrated diagnostic utility (AUC: 0.741) with proposed thresholds of < 39.5 cm (males) and < 36.5 cm (females), yielding moderate sensitivity (69.7% for males, 82.2% for females) and acceptable specificity (78.9% for males, 62.6% for females). Questionnaire-based tools showed limited diagnostic accuracy with SARC-CalF performing the best (AUC: 0.789, sensitivity: 48.7%, specificity: 93.2%). Among physical performance tests, handgrip strength was the most accurate (AUC: 0.716), although these tests generally exhibited high sensitivity, but lower specificity.</p><p><strong>Conclusion: </strong>Calf circumference was the most effective screening tool for sarcopenia in people with T2DM. Neck circumference emerged as a promising alternative at optimal cutoff values, offering a simple, novel and practice screening tool option. These findings support the implementation of anthropometric measures for sarcopenia screening in clinical settings, particularly in outpatient care.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"346"},"PeriodicalIF":3.4,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A nomogram for predicting the risk of malnutrition in hospitalized older adults: a retrospective study. 预测住院老年人营养不良风险的nomogram:一项回顾性研究。
IF 3.4 2区 医学
BMC Geriatrics Pub Date : 2025-05-16 DOI: 10.1186/s12877-025-05990-x
Qianwen Jiang, Feika Li, Gang Xu, Lina Ma, Xiushi Ni, Qing Wang, Jinhui Wu, Fang Wu
{"title":"A nomogram for predicting the risk of malnutrition in hospitalized older adults: a retrospective study.","authors":"Qianwen Jiang, Feika Li, Gang Xu, Lina Ma, Xiushi Ni, Qing Wang, Jinhui Wu, Fang Wu","doi":"10.1186/s12877-025-05990-x","DOIUrl":"https://doi.org/10.1186/s12877-025-05990-x","url":null,"abstract":"<p><strong>Background: </strong>Malnutrition is highly prevalent but under-recognized in hospitalized older adults, which is closely related to increased risk of adverse clinical outcomes and mortality. It is crucial to identify high-risk individuals at an early stage and manage them promptly. This study aimed to explore the predictive factors and develop a nomogram model for predicting the risk of malnutrition in hospitalized elderly patients.</p><p><strong>Methods: </strong>We conducted a retrospective study of data collected from 456 older individuals admitted to geriatric wards from four hospitals in China between August 2020 and December 2020 (136 in the malnutrition group and 320 in the non-malnutrition group). Least Absolute Selection and Shrinkage Operator (LASSO) regression and stepwise multivariate logistic regression were applied to screen predictors and create a nomogram. The predictive performance of the model was assessed by receiver operating characteristic (ROC) curve, concordance index (C-index) and calibration curve. The clinical utility was estimated by decision curve analysis (DCA). Youden's Index was used to identify the optimal cut-point of the nomogram.</p><p><strong>Results: </strong>Four independent predictive factors were utilized to construct the nomogram model after being selected by LASSO regression and multivariate logistic regression, namely body mass index (BMI), heart failure, frailty and hemoglobin. C-index of the model was 0.906 (95% CI: 0.872-0.939) and the area under the curve (AUC) was 0.906. The optimal cut-point of the nomogram was 82.74 with a sensitivity of 78.7% and specificity of 92.2% (Youden's index: 0.709). The calibration curve demonstrated a high degree of consistency between predicted probability and actual observation. The DCA indicated a favorable clinical benefit for the nomogram.</p><p><strong>Conclusions: </strong>We have established a multi-dimensional nomogram model to predict the risk of malnutrition in Chinese hospitalized older adults. The model yields favorable predictive performance and clinical utility, which provides an effective approach for rapid identification of high-risk malnourished older individuals in clinical practice.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"345"},"PeriodicalIF":3.4,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of high-power single-ring isolation and box isolation in elderly patients with persistent atrial fibrillation. 高倍单环隔离与箱隔离在老年持续性心房颤动患者中的比较。
IF 3.4 2区 医学
BMC Geriatrics Pub Date : 2025-05-16 DOI: 10.1186/s12877-025-05981-y
Yanbin Song, Xiaofang Liang, Sheliang Xue, Bo Xu, Jianqiang Xiao, Wenhua Li
{"title":"Comparison of high-power single-ring isolation and box isolation in elderly patients with persistent atrial fibrillation.","authors":"Yanbin Song, Xiaofang Liang, Sheliang Xue, Bo Xu, Jianqiang Xiao, Wenhua Li","doi":"10.1186/s12877-025-05981-y","DOIUrl":"https://doi.org/10.1186/s12877-025-05981-y","url":null,"abstract":"<p><strong>Background: </strong>This study evaluated the superiority of single-ring isolation (SRI) over box isolation using high power in elderly patients with persistent atrial fibrillation (PeAF).</p><p><strong>Methods: </strong>We retrospectively studied elderly patients with PeAF who underwent primary catheter ablation. The patients were divided into the SRI group and the posterior box isolation (BOXI) group. Basic characteristics, procedural variables, complications and atrial arrhythmia recurrence rates were collected.</p><p><strong>Results: </strong>Forty-five pairs of patients in the two groups were matched by 1:1 PSM. Compared with that in the BOXI group, the total procedure time in the SRI group was not significantly different (P = 0.340). However, there were significant reductions in the total ablation time, ring ablation lesions and number of lesions on the posterior wall in patients who underwent SRI compared to those who underwent BOXI (all P < 0.001). The cardiac troponin level in the SRI group was significantly lower (P = 0.023). There were significantly fewer mismatched three-dimensional mapping models and mismatched models per patient due to pain-induced movement in the SRI group (all P < 0.05). The questionnaires revealed that the pain score was significantly lower in the SRI group than in the BOXI group (P < 0.001). In addition, significantly fewer patients with SRI than with BOXI experienced gastrointestinal symptoms after the procedure (15.56% vs. 37.78%, P = 0.017). K‒M analysis revealed no significant difference in atrial arrhythmia-free survival at 12 months between the SRI and BOXI patients (P > 0.05).</p><p><strong>Conclusions: </strong>High-power SRI is safe and feasible and may be superior to the BOXI for experience of elderly patients with PeAF.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"344"},"PeriodicalIF":3.4,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mediating role of frailty/pre-frailty on the association between exercise participation and traffic crashes among Japanese community-dwelling older drivers. 日本社区老年驾驶员运动参与与交通事故的关联:虚弱/前虚弱的中介作用
IF 3.4 2区 医学
BMC Geriatrics Pub Date : 2025-05-15 DOI: 10.1186/s12877-025-05998-3
Jue Liu, Yuya Fujii, Keisuke Fujii, Jaehoon Seol, Koki Nagata, Tomohiro Okura
{"title":"Mediating role of frailty/pre-frailty on the association between exercise participation and traffic crashes among Japanese community-dwelling older drivers.","authors":"Jue Liu, Yuya Fujii, Keisuke Fujii, Jaehoon Seol, Koki Nagata, Tomohiro Okura","doi":"10.1186/s12877-025-05998-3","DOIUrl":"10.1186/s12877-025-05998-3","url":null,"abstract":"<p><strong>Background: </strong>Driving is essential for maintaining independence. This study aimed to assess the mediating role of frailty status in the association between exercise participation and traffic crashes among Japanese community-dwelling older drivers.</p><p><strong>Methods: </strong>This 2-year longitudinal study included data of 3,934 Japanese community-dwelling older drivers aged ≥ 65 years in Kasama City who did not require long-term care and participated in a postal survey in 2019 and 2021 at baseline and follow-up, respectively. The participants who exercised at least one-three times per month at baseline were classified as exercisers. Frailty status was assessed using the seven-domain Kihon Checklist. A self-reported history of traffic crashes was collected during the follow-up survey. The effect of exercise participation on traffic crash involvement was analyzed using logistic regression after adjusting for covariates. Mediation analyses were performed to determine the mediating effects of frailty status.</p><p><strong>Results: </strong>A total of 357 (23.7%) and 1,147 (76.3%) older drivers were classified as exercisers and non-exercisers, respectively. Logistic regression analyses showed that exercise participation significantly reduced the risk of traffic crash involvement at follow-up (odds ratio [OR] = 0.586; 95% confidence interval [CI], 0.359-0.956) and was significantly associated with a lower risk of frailty/pre-frailty (OR = 0.479; 95% CI, 0.372-0.617). Although there was no significant association between exercise participation and traffic crash involvement at follow-up (OR = 0.631; 95% CI, 0.384-1.037), frailty/pre-frailty was associated with a significantly higher risk of traffic crash involvement compared with robustness (OR = 1.649; 95% CI, 1.061-2.563). The Sobel test revealed that frailty/pre-frailty mediated the association between exercise participation and traffic crash involvement at follow-up (p =.01). Additionally, among the seven domains of the Kihon Checklist, the physical domain mediated the association between exercise participation and traffic crash involvement at follow-up (p =.01).</p><p><strong>Conclusions: </strong>Exercise participation could significantly lower the risk of traffic crashes, with frailty/pre-frailty acting as a mediating factor. Our findings indicated that managing frailty is crucial for both public health and crash prevention, emphasizing the need for promoting these measures among older drivers.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"341"},"PeriodicalIF":3.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12079984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding and integrating the needs and preferences of people living with dementia in the inpatient setting: a qualitative study. 理解和整合住院痴呆患者的需求和偏好:一项定性研究。
IF 3.4 2区 医学
BMC Geriatrics Pub Date : 2025-05-15 DOI: 10.1186/s12877-025-05932-7
Alyse Lennox, Denise Goodwin, Felicity Leavold, Renae Nicol, Velandai Srikanth, Darshini Ayton, Madeleine Berends, Myra Thiessen, Daphne Flynn, Chris Moran
{"title":"Understanding and integrating the needs and preferences of people living with dementia in the inpatient setting: a qualitative study.","authors":"Alyse Lennox, Denise Goodwin, Felicity Leavold, Renae Nicol, Velandai Srikanth, Darshini Ayton, Madeleine Berends, Myra Thiessen, Daphne Flynn, Chris Moran","doi":"10.1186/s12877-025-05932-7","DOIUrl":"10.1186/s12877-025-05932-7","url":null,"abstract":"<p><strong>Background: </strong>People living with dementia (PLWD) have poorer outcomes than cognitively normal people when admitted to hospital. One reason for this difference is related to the challenges in learning and integrating the needs and preferences of PLWD into clinical care. We aimed to obtain a range of perspectives on the challenges in supporting PLWD in hospital and explore opportunities for improvement.</p><p><strong>Methods: </strong>Using an exploratory qualitative study design, we conducted interviews with nine people supporting PLWD (current / ex-spouses or children of PLWD) and 11 nursing, medical and allied health staff members at a single Australian hospital. Data were thematically analysed using a framework approach.</p><p><strong>Results: </strong>Participants described how best practice in supporting PLWD included understanding and integrating patient needs and highlighted the importance of family and the multidisciplinary team working in partnership. A number of factors inhibiting quality care provision were described, including uncertainty around responsibility for communicating with families to understand needs of PLWD; unsuitable tools; lack of opportunities for families to communicate with staff; and, resource and environmental constraints. Participants discussed potential for improvement, emphasising the need for a pre-emptive, rather than reactive solution. They expressed support for the idea of a 'hospital admission kit', containing both information about PLWD and their familiar items. Implementation considerations were also noted, with various perspectives on the timing of initiation, updating, responsible person(s), format, content and how it should be incorporated into clinical workflows.</p><p><strong>Conclusions: </strong>We found that hospital staff and those supporting PLWD felt that integrating the needs and preferences of PLWD into hospital care was important. The concept of a pre-prepared 'toolkit' that was ready in the case of a need to attend hospital was felt to be valid and potentially helpful. More work is required to design aspects such as format, content and the workflows needed to generate accountability and reliability in creating, updating and incorporating it into hospital care.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"342"},"PeriodicalIF":3.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080157/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors associated with mental health literacy and demand for mental health services among older adults in China: a cross-sectional study. 中国老年人心理健康素养和心理健康服务需求的相关因素:一项横断面研究
IF 3.4 2区 医学
BMC Geriatrics Pub Date : 2025-05-15 DOI: 10.1186/s12877-025-06003-7
Haihui Chen, Zijuan Ma, Ruidian Huang, Yujing Liu, Lianghua Li, Zhengyuan Zhou, Dongfang Wang, Wei Wang, Junxu Lin, Weishi Lin, Luning Yin, Rui Zhang, Xuan Mo, Yunge Fan, Fang Fan
{"title":"Factors associated with mental health literacy and demand for mental health services among older adults in China: a cross-sectional study.","authors":"Haihui Chen, Zijuan Ma, Ruidian Huang, Yujing Liu, Lianghua Li, Zhengyuan Zhou, Dongfang Wang, Wei Wang, Junxu Lin, Weishi Lin, Luning Yin, Rui Zhang, Xuan Mo, Yunge Fan, Fang Fan","doi":"10.1186/s12877-025-06003-7","DOIUrl":"10.1186/s12877-025-06003-7","url":null,"abstract":"<p><strong>Background: </strong>There is limited research on mental health literacy (MHL) among Chinese older adults as well as their demand and willingness for mental health services (MHS). This study investigated the factors associated with them among Chinese older adults. Additionally, predictors of MHL as well as demand and willingness for MHS were compared between older adults living alone and those not living alone.</p><p><strong>Methods: </strong>This study is a cross-sectional study conducted among 494 older adults in Guangzhou, China. Sociodemographic characteristics, frequency of participating in community-based activities, mental health status, MHL, and demand and willingness for MHS were assessed through self-reported questions. A series of logistic regression analyses were conducted to examine factors associated with the MHL and demand and willingness for MHS.</p><p><strong>Results: </strong>The awareness rates for the three MHL-related questions were between 65.3% and 73.7%, and 62.0% and 69.6% of the participants indicated the demand and willingness, respectively, for MHS. Frequently participating in community-based activities increased the likelihood of awareness of the MHL-related questions (ORs = 2.92-4.18, CIs = [1.50,9.28]), as well as the demand and willingness for MHS (ORs = 2.16-2.24, CIs = [1.19,4.20]). Similar significant associations were found among the older adults who were not living alone but not among those living alone.</p><p><strong>Conclusions: </strong>Based on the results of this study, policymakers and clinicians are advised to develop more targeted community-based activities for older adults and focus especially on those living alone to enhance their MHL and increase willingness for MHS.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"343"},"PeriodicalIF":3.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12079844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the efficacy and safety of remimazolam and propofol for fiberoptic bronchoscopy in older patients: a prospective, randomized controlled study. 雷马唑仑和异丙酚用于老年患者纤维支气管镜检查的疗效和安全性比较:一项前瞻性、随机对照研究。
IF 3.4 2区 医学
BMC Geriatrics Pub Date : 2025-05-14 DOI: 10.1186/s12877-025-05984-9
Binggao Chai, Jiaxi Guo, Zhiwei Xu, Tao Chen, Hongquan Wang, Zhenqiang Zhu, Jian Zhong, Kanzheng Chen, Jianlong Du, Xianhui Kang
{"title":"Comparison of the efficacy and safety of remimazolam and propofol for fiberoptic bronchoscopy in older patients: a prospective, randomized controlled study.","authors":"Binggao Chai, Jiaxi Guo, Zhiwei Xu, Tao Chen, Hongquan Wang, Zhenqiang Zhu, Jian Zhong, Kanzheng Chen, Jianlong Du, Xianhui Kang","doi":"10.1186/s12877-025-05984-9","DOIUrl":"https://doi.org/10.1186/s12877-025-05984-9","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to compare the efficacy and safety of remimazolam with those of propofol in older patients undergoing fiberoptic bronchoscopy with preserved spontaneous breathing.</p><p><strong>Methods: </strong>Sixty older patients were randomly and equally divided into a remimazolam group (group R) and a propofol group (group P). Both groups received 0.15 µg/kg of sufentanil for analgesia. Group R received an initial dose of 0.2 mg/kg remimazolam and was injected with a maintenance dose of 1 mg/kg/h. Group P received an initial dose of 2 mg/kg propofol and was injected with a maintenance dose of 4 mg/kg/h. The primary evaluation indicators were the success rate of sedation and the incidence of hypotension. The secondary evaluation indicators were respiratory depression, hypertension, tachycardia, bradycardia, awakening time, quality of recovery-15 (QOR-15) score, patient satisfaction, physician satisfaction, and adverse events.</p><p><strong>Results: </strong>Success rates of sedation were similar between group R (96.7%) and group P (100%). The incidence of hypotension in group R was lower than that in group P (2/30 vs. 10/30, p = 0.01). Respiratory depression was lower in group R than in group P (3/30 vs. 10/30, p = 0.03). Fewer patients reported injection pain in group R (0/30 vs. 7/30, p = 0.01). There were no significant differences in hypertension, tachycardia, bradycardia, awakening time, QoR-15 score, patient satisfaction, physician satisfaction, or adverse events between the two groups.</p><p><strong>Conclusions: </strong>Remimazolam has a high sedation success rate for painless fiberoptic bronchoscopy in older patients, and the incidence of hypotension and respiratory depression is lower than that of propofol. Remimazolam may be a better choice for sedation during painless fiberoptic bronchoscopy in older patients with preserved spontaneous breathing.</p><p><strong>Trial registration: </strong>ChiCTR2300069041; 6/3/2023.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"337"},"PeriodicalIF":3.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12076816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Construction and evaluation of a nomogram model for predicting the risk of hospital-acquired pneumonia in elderly patients with acute ischemic stroke. 预测老年急性缺血性脑卒中患者医院获得性肺炎风险的nomogram模型的构建与评价。
IF 3.4 2区 医学
BMC Geriatrics Pub Date : 2025-05-14 DOI: 10.1186/s12877-025-05936-3
Man Huang, Wan Wang, Wu-Lin Li, Yan-Qing Chen, Xian-Ting Chen, Ye Liu, Yan Li, Dong-Mei Ren, Fei Wang
{"title":"Construction and evaluation of a nomogram model for predicting the risk of hospital-acquired pneumonia in elderly patients with acute ischemic stroke.","authors":"Man Huang, Wan Wang, Wu-Lin Li, Yan-Qing Chen, Xian-Ting Chen, Ye Liu, Yan Li, Dong-Mei Ren, Fei Wang","doi":"10.1186/s12877-025-05936-3","DOIUrl":"https://doi.org/10.1186/s12877-025-05936-3","url":null,"abstract":"<p><strong>Objective: </strong>In this study, we aimed to develop and validate an easy-to-use model to predict the risk of hospital-acquired pneumonia (HAP) in elderly patients with acute ischemic stroke (AIS).</p><p><strong>Methods: </strong>A total of 2861 elderly AIS patients who were admitted to Jiading District Central Hospital Affiliated with Shanghai University of Medicine & Health Science from January 2016 to December 2023 were selected. Among these patients, 699 were diagnosed with HAP (HAP group), and 2162 patients were included in the control group (non-HAP group). Univariate and multivariate logistic regression analyses were performed to determine the risk factors for HAP after AIS. These factors were then used to establish a scoring system, from which a nomogram model was developed with R software.</p><p><strong>Results: </strong>Univariate analysis revealed 17 factors that were significantly associated with the development of HAP after AIS in elderly patients (P < 0.05). Multivariate logistic regression analysis including these factors revealed that age, the national institute of health stroke scale (NIHSS) score within 24 h of admission (Kwah LK. J Physiother 60:61, 2014), the stress hyperglycemia ratio (SHR), smoking status, and dysphagia status were independent risk factors for HAP after AIS. According to the oxfordshire community stroke project (OCSP) classification, patients classified as having the total anterior circulation infarct (TACI), partial anterior circulation infarct (PACI), and posterior circulation infarct (POCI) sub-types had a significantly increased risk of HAP compared with those classified as having the lacunar infarct (LACI) sub-type. A nomogram model constructed from these six risk factors yielded a C-index of 0.834 (95% confidence interval (CI): 0.811-0.857), indicating high accuracy. Calibration and clinical decision curve analyses revealed the reliability and clinical value of the proposed model.</p><p><strong>Conclusion: </strong>Our proposed nomogram provides clinicians with a simple and reliable tool for predicting HAP from conventional data. The model can also help clinicians make personalized treatment decisions for patients at different risk levels.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"340"},"PeriodicalIF":3.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of frailty and association with intrinsic capacity decline among community-dwelling older people in Cameroon: a cross sectional study. 在喀麦隆社区居住的老年人中,虚弱的患病率及其与内在能力下降的关系:一项横断面研究。
IF 3.4 2区 医学
BMC Geriatrics Pub Date : 2025-05-14 DOI: 10.1186/s12877-025-06011-7
Marie-Josiane Ntsama Essomba, Régine Mylène Mballa Mba, Landry Ekwalla Kameni, Patrick Tchebegna, Florence Denise Mvondo Lema, Maturin Tabue-Teguo
{"title":"Prevalence of frailty and association with intrinsic capacity decline among community-dwelling older people in Cameroon: a cross sectional study.","authors":"Marie-Josiane Ntsama Essomba, Régine Mylène Mballa Mba, Landry Ekwalla Kameni, Patrick Tchebegna, Florence Denise Mvondo Lema, Maturin Tabue-Teguo","doi":"10.1186/s12877-025-06011-7","DOIUrl":"https://doi.org/10.1186/s12877-025-06011-7","url":null,"abstract":"<p><strong>Background: </strong>Frailty and impairment in intrinsic capacity (IC) have been shown to increase the risk of poor outcomes in older people. We aimed to determine the prevalence of frailty and its association with decline in IC among people aged 60 and over in Cameroon.</p><p><strong>Methods: </strong>This cross-sectional study included community-dwellers aged ≥ 60 years. Frailty was assessed using Fried's criteria and IC decline using step 1 of the Integrated Care for Older People (ICOPE). Any abnormality reported for one of the six IC domains was considered as a positive screening. The significance level was p < 0.05.</p><p><strong>Results: </strong>Among 108 participants included (64.8% women, median age 70 years (65-75)), all had a decline of at least one IC. The prevalence of frailty was 52.8%.The main domains involved were cognition (93.5%), vision (88%) and hearing (87%). Compared to participants without frailty, the frail group was older, achieved lower education, had fewer children, had a more frequent history of falls and a higher number of deficits in IC domains. In the multivariable model, after adjusting for age, sex and comorbidities, the participants with preserved mobility (OR 0.18, 95%CI 0.068-0.49) and vitality (OR 0.11 95%CI 0.04-0.28) were likely to have a lower risk of frailty.</p><p><strong>Conclusion: </strong>Frailty and IC impairment were common in this group of older Cameroonians. Further research with the monitoring of trajectories of IC and frailty as a research outcome may allow better comparison to tailor interventions taking into account our local resources.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"335"},"PeriodicalIF":3.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12076898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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