BMC Geriatrics最新文献

{"title":"Technology readiness among UK-based cognitively unaffected older adults during the COVID-19 pandemic: potential implications for decentralised alzheimer's disease prevention trials.","authors":"S Taylor, L Dunn, C Udeh-Momoh, K Abbott, P Giannakopoulou, L Middleton, O Robinson, J Kalsi, D Kafetsouli, J Ford","doi":"10.1186/s12877-025-06158-3","DOIUrl":"https://doi.org/10.1186/s12877-025-06158-3","url":null,"abstract":"<p><strong>Background: </strong>Alzheimer's disease (AD) remains a global health and socioeconomic burden. Telemedicine has been more widely used since the beginning of the COVID-19 pandemic and may be an effective strategy to mitigate the rising costs associated with AD. This study aimed to assess technology readiness among older adults at risk of developing dementia, with the goal of informing the design and delivery of technology-based approaches in AD prevention research.</p><p><strong>Methods: </strong>Cognitively unaffected older adults (n = 226) from the CHARIOT PRO Substudy were invited to complete the CHARIOT Technology Questionnaire (CTQ). CTQ assessed technology experiences and attitudes, including 'technology readiness' via the Technology Readiness Index (TRI).</p><p><strong>Results: </strong>Female participants scored, on average, lower TRI (M = 27.50, SD = 6.87) compared to males (M = 29.50, SD = 6.02). Furthermore, age predicted levels of technology readiness. Exploratory factor analysis determined two factors: \"Technology Competence\" (Factor 1) and \"Technology Trepidation\" (Factor 2). Gender differences were found for \"Technology Competence\" (but not \"Technology Trepidation\"), and age predicted \"Technology Trepidation\" (but not \"Technology Competence\").</p><p><strong>Discussion: </strong>Differences in gender, age, \"Technology Competence\", and \"Technology Trepidation\" may highlight those who need additional study and/or support in remote-based AD dementia prevention trials.</p><p><strong>Conclusions: </strong>COVID-19 has accelerated our adoption of 'digitalisation' in AD dementia research. A deeper understanding of the barriers to technology readiness may help inform future AD research studies.</p><p><strong>Trial registration: </strong>The CHARIOT PRO SubStudy is registered with clinicaltrials.gov (NCT02114372).</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"563"},"PeriodicalIF":3.8,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between social isolation and cognitive function in older patients with chronic obstructive pulmonary disease: a latent profile analysis.","authors":"Minghua Han, Hongxia Wu, Huize Xu, Jian Zhao, Zhongwen Chang, Qian Zhao","doi":"10.1186/s12877-025-06211-1","DOIUrl":"https://doi.org/10.1186/s12877-025-06211-1","url":null,"abstract":"<p><strong>Background: </strong>To explore the potential classes of social isolation in older patients with chronic obstructive pulmonary disease (COPD), analyze the influencing factors of these classes, and investigate the relationship between different classes and cognitive function.</p><p><strong>Methods: </strong>From April to December 2024, a convenience sampling method was used to survey older COPD patients at a tertiary hospital in Shanxi Province. The general information questionnaire, Social Network Scale Brief, Hamilton Depression Scale, Social Support Rating Scale, and Montreal Cognitive Assessment Scale were employed. Latent profile analysis was conducted to categorize social isolation in older COPD patients. Uni-variate and multivariate analyses were used to explore the influencing factors of different social isolation classes, and a mixed-effects regression model was applied to analyze the relationship between these classes and cognitive function.</p><p><strong>Results: </strong>A total of 245 older COPD patients were included, with 33.5% experiencing social isolation. Social isolation in older COPD patients could be divided into three classes, named \"High Social Isolation-Interaction Deficiency Group\", \"Moderate Social Isolation-Moderate Interaction Group\", and \"Low Social Isolation-Coordinated Relationship Development Group\", accounting for 27.4%, 43.9%, and 28.7% of the sample, respectively. The unordered multinomial results indicated that older age, living alone, annual household income per capital below 7000-Yuan, acute exacerbation history within the last month, and high levels of depression were more likely to be associated with the \"High Social Isolation-Interaction Deficiency Group\". Patients with low education levels and annual household income per capital between 7000 and 15,000 Yuan were more likely to belong to the \"Moderate Social Isolation-Moderate Interaction Group\". Patients with moderate airflow limitation, long disease duration, and high levels of social support were more likely to belong to the \"Low Social Isolation-Coordinated Relationship Development Group\". The mixed-effects regression model analysis showed that patients in the \"High Social Isolation-Interaction Deficiency Group\" were at a higher risk of cognitive impairment compared to the other two groups.</p><p><strong>Conclusion: </strong>The findings reveal a significant association between social isolation patterns and cognitive dysfunction risk in older COPD patients. Nurses and healthcare providers should prioritize screening for cognitive impairment in the \"High Social Isolation-Interaction Deficiency Group\", as this subgroup exhibits the highest prevalence of cognitive deficits. Future interventions may consider tailoring strategies to address distinct social isolation profiles, pending validation through longitudinal or experimental studies to establish causal pathways.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"561"},"PeriodicalIF":3.8,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A composite risk score to identify older adults at high risk of hearing loss in a community screening program.","authors":"Juan Juan Li, Wei Xiang Gao, Jiao Wang, Yan Hong Zhang, Fei Ji, Yao Dan Yuan, Peng Zhang, Fang Ma, Lin Xu, Xian Hai Zeng","doi":"10.1186/s12877-025-06208-w","DOIUrl":"https://doi.org/10.1186/s12877-025-06208-w","url":null,"abstract":"<p><strong>Background: </strong>Age-related hearing loss (HL) is highly prevalent among older adults, yet it often goes undetected and untreated. Routine screening in community settings is not widespread, and hearing aid uptake remains very low. We aimed to construct a composite risk score to identify individuals at high risk of HL for targeted audiometric screening.</p><p><strong>Methods: </strong>We conducted a cross-sectional study using data from a community-based health screening program in Shenzhen, China. Participants underwent pure-tone audiometry at 500-8000 Hz to determine hearing thresholds. Moderate or greater HL was defined as a pure-tone average (PTA) ≥ 35dB in the better ear. Stepwise multivariable regression was used to identify predictors of HL, which were then used to develop a cumulative Hearing Risk Score (HRS).</p><p><strong>Results: </strong>A total of 2,490 adults (mean age, 67.5 years, SD 5.8 years) were included; 32.5% (810 participants) had moderate or greater hearing loss. Of 22 risk factors included in the stepwise regression model, seven were identified: self-reported hearing difficulty, age 65 years or older, male sex, social isolation, cardiovascular disease, and metabolic disease. These were incorporated into the HRS, with total scores ranging from 1 to 23. The HRS was strongly associated with moderate or greater hearing loss, with adjusted odds ratios increasing from 4.50 (95% confidence interval (CI), 1.57-12.88) for a score of 1 to 39.11 (13.50-113.33) for a score of 6 or more (P for trend < 0.001). Similar dose-response patterns were observed at all frequencies tested (0.5 to 8 kHz).</p><p><strong>Conclusions: </strong>The HRS showed a clear dose-response relationship with HL and may serve as a practical tool to target older adults for confirmatory audiologic evaluation.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"565"},"PeriodicalIF":3.8,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The social geography of fear and acceptance: an interview study on attitudes toward LGBQ identities in residential aged care.","authors":"Klara Le","doi":"10.1186/s12877-025-06234-8","DOIUrl":"https://doi.org/10.1186/s12877-025-06234-8","url":null,"abstract":"<p><strong>Background: </strong>Older LGBQ (lesbian, gay, bisexual and queer/questioning) adults in residential aged care (RAC) navigate environments shaped by heteronormative norms, institutional structures, and the social dynamics of communal living. Unlike in private homes, RAC settings bring together individuals with diverse backgrounds, values, and attitudes, creating both opportunities for inclusion and risks of exclusion. This study examines how both LGBQ and non-LGBQ residents contribute to shaping the social and cultural conditions of RAC and how these dynamics influence older LGBQ adults' ability to express their sexual identity.</p><p><strong>Methods: </strong>This study employed a qualitative approach, conducting semi-structured interviews with 17 residents aged 78-95 years in Swedish RAC, including five individuals who identified within the LGBQ spectrum. A thematic reflexive analysis was conducted, drawing on Valentine's Social geography to examine how institutional norms, peer dynamics, and spatial conditions influence residents' opportunities to express their sexuality.</p><p><strong>Results: </strong>Findings revealed three main themes: Geography of RAC: Space and Norms, Sexual Identity and Belonging and Strategies for Safety and Visibility. The results suggests that heteronormativity and perceptions of ageing shape the attitudes within RAC environments, often rendering older LGBQ adults invisible as sexual beings. The presence and attitudes of other residents were found to play an important role in shaping the space, either reinforcing exclusion or fostering belonging. LGBQ residents described employing various strategies to navigate this terrain. While some participants experienced a sense of restriction, others found ways to assert their identity and challenge dominant norms.</p><p><strong>Conclusions: </strong>The study highlights that RAC is not only structured by formal policies but also co-created through everyday interactions among residents and staff. While previous research has emphasised the need for staff training and inclusive policies, these findings suggest that education alone may not be sufficient. This study argues that there may be value in establishing dedicated residential care facilities that are explicitly LGBTQ-friendly.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"562"},"PeriodicalIF":3.8,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Kinesio taping and extracorporeal shock wave therapy in combination with exercise in sarcopenic older adults: a study protocol of a double-blinded, randomized controlled trial.","authors":"Jiani Lu, Jie Liu, Yiyi Chen, Yilan Sheng, Lihua Chen, Fei He, Wenhua Chen, Bo Yu","doi":"10.1186/s12877-025-06251-7","DOIUrl":"https://doi.org/10.1186/s12877-025-06251-7","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenia is an age-related disease characterized by loss of muscle mass and strength, and its prevalence is increasing. Exercise is an effective treatment to improve muscle mass, muscle strength, and functional activity in sarcopenic older adults. Kinesio taping (KT) and extracorporeal shock wave therapy (ESWT) are widely-used treatments for musculoskeletal disorders and can increase muscle performance and/or muscle mass. However, the potential synergistic effects of combining KT and ESWT with exercise for primary sarcopenia remain unknown. This study aims to determine whether the addition of KT and ESWT could enhance the beneficial effects of exercise on sarcopenia.</p><p><strong>Methods: </strong>Nighty-four older adults (60 to 75 years old) with sarcopenia will be recruited and assigned randomly into two groups: (1) exercise + placebo ESWT + placebo taping and (2) exercise + ESWT + KT. All participants will undergo an 8-week treatment program, and outcomes will be measured at recruitment and 1, 4, and 8 weeks after the initial treatment. The primary outcome will be skeletal muscle index, and the secondary outcomes will be knee muscle strength, muscle tone, gait speed, timed-up-and-go test, five-time chair test, Short Physical Performance Battery, and biomarkers in blood. Two-way repeated measure ANOVA will be used to analyze the differences between the two groups at each time point.</p><p><strong>Discussion: </strong>This RCT will fill crucial evidence gaps by evaluating the first combined KT + ESWT + exercise protocol for sarcopenia. Our results will determine whether this novel strategy outperforms standard exercise therapy while expanding KT/ESWT indications beyond their current musculoskeletal uses.</p><p><strong>Trial registration: </strong>Chinese Clinical Trial Registry (http//www.chictr.org.cn) register number ChiCTR2200064269.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"560"},"PeriodicalIF":3.8,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of rheumatoid arthritis in older patients: a cross-sectional study.","authors":"Ramesh Kumar Sah, A B Dey, P Chatterjee, A Chakrawarty, Uma Kumar, S N Dwivedi, C J Das","doi":"10.1186/s12877-025-06242-8","DOIUrl":"https://doi.org/10.1186/s12877-025-06242-8","url":null,"abstract":"<p><strong>Background: </strong>Rheumatoid Arthritis (RA) in older adults is a chronic inflammatory condition causing severe disability and impacting patients' physical, psychological, and social health. It lowers productivity in society and puts pressure on healthcare systems. This study aims to explore the different aspects of RA and investigate the diagnostic potential of serum marker 14-3-3η.</p><p><strong>Method: </strong>This Cross-sectional study recruited 205 arthritis patients (63 RA and 142 OA) over sixty years old. The participants underwent a thorough clinical evaluation according to the established design. Anti-CCP and serum 14-3-3η levels were measured. Simple logistic regression was performed to identify significant predictors of RA. ROC curve determined optimal cut-off value for 14-3-3η.</p><p><strong>Results: </strong>This study reported an average age of 63.67 years with a high female-to-male ratio of 4:1 in the RA cohort, while in the OA cohort, the mean age was 65.5 years with a low female-to-male ratio of 2:1 overall. Symptomatically, RA patients exhibited earlier onset, pronounced early morning stiffness, fever, weight loss, myalgia, and fatigue, all with highly significant p-values (< 0.001). Comorbidities showed higher incidences of anemia, ILD, and osteoporosis in RA patients. Impaired ADL and IADL were noted in 17.5% and 73.2%, respectively. Impaired HMSE and GDS were found in 36.5% and 74.6%, respectively. Logistic regression analysis identified key predictors distinguishing RA from OA, including EMS (OR: 1.09, p < 0.001), fever (OR: 6.68, p < 0.001), weight loss (OR: 6.35, p < 0.001), myalgia (OR: 5.07, p < 0.001), osteoporosis (OR: 2.21, p = 0.013), ACCP levels (OR: 1.28, p < 0.001), and the novel marker 14-3-3η (OR: 2.87, p = 0.047). Using both ACCP and14-3-3η markers, 88.88% of RA patients were positive for at least one marker, enhancing its diagnostic coverage. Elderly onset RA (EORA) patients had a significantly higher age and shorter disease duration compared to those with young onset RA (YORA). The female-to-male ratio in the YORA and EORA group were 6.97:1 and 1.66:1 respectively. PMR-like symptoms were more prevalent in the EORA group (31.25% vs.14.9%). Hypothyroidism was more frequent in the EORA group (31% vs. 17%). Sulfasalazine was more commonly prescribed in both EORA (100%) and YORA (89%) groups.</p><p><strong>Conclusion: </strong>This study contributes to a better understanding of distinguishing RA from OA. It also highlights the differences between young and elderly onset RA, and supports the diagnostic potential of the serum marker 14-3-3η.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"564"},"PeriodicalIF":3.8,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the dilemma of secondary fracture prevention in Chinese families from the experience of elderly fragility fractures: a qualitative study based on Confucian cultural background.","authors":"Nan Tang, Lingjie Jiang, Mingxing Lei, Qingqing Su, Jie Song, Dan Kong, Xiang Cui, Yuan Gao","doi":"10.1186/s12877-025-06236-6","DOIUrl":"10.1186/s12877-025-06236-6","url":null,"abstract":"<p><strong>Background: </strong>Osteoporotic secondary fractures are associated with high mortality and poor prognosis. However, little is known about subsequent fracture prevention behaviors in the home environment, especially regarding the experiences, perceptions, and decisions of patients and family caregivers.</p><p><strong>Methods: </strong>A purposive sampling method was used to select 20 elderly patients with osteoporotic subsequent fractures and 10 family caregivers from a tertiary hospital in Beijing for semi-structured interviews. The interviews were transcribed verbatim and analyzed using thematic analysis.</p><p><strong>Results: </strong>Participants described three interconnected themes: internalized negative age stereotypes, attitude-driven osteoporosis management deficiencies, and family caregiving challenges under Confucian culture. Internalized negative age stereotypes profoundly affected elderly individuals' attitudes and behaviors toward fragility fractures and health management through a dual mechanism of decreased behavioral autonomy and negative outcome expectations. Meanwhile, attitude-driven osteoporosis management deficiencies significantly increased the risk of subsequent fractures. The effectiveness of family caregiving under Confucian culture varied according to differences in cognition, beliefs, and cultural identity.</p><p><strong>Conclusion: </strong>This qualitative study provides new insight into the dilemma of subsequent fragility fracture prevention among elderly individuals. Starting from cultural concepts and proactive health education, helping the elderly establish a positive attitude toward aging can enhance their awareness of subsequent fracture prevention and treatment, as well as their initiative and confidence in health management. Meanwhile, perpetuating the beneficial effects of Confucian culture and enhancing community support for family caregiving may contribute to improved health management of elderly individuals with fragility fractures.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"559"},"PeriodicalIF":3.8,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12308990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144741147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiences and outcomes of older adults with obesity transitioning from gym- to home-based resistance training due to COVID-19 lockdowns: a mixed-methods analysis of a RCT.","authors":"Costas Glavas, Jakub Mesinovic, Anoohya Gandham, Mavil May Cervo, Carrie-Anne Ng, Peter R Ebeling, Elena S George, Robin M Daly, Belinda R Beck, Paul Jansons, David Scott","doi":"10.1186/s12877-025-06247-3","DOIUrl":"10.1186/s12877-025-06247-3","url":null,"abstract":"<p><strong>Background: </strong>Supervised gym-based high-intensity resistance and impact training (HiRIT) can enhance physical function and muscle strength, but older adults may face challenges affecting adherence to HiRIT, such limited access to facilities and lack of transportation, necessitating a shift towards unsupervised home-based exercise. The aim of this study was to explore experiences and perspectives of older adults with obesity who were required to transition from supervised gym-based HiRIT to unsupervised home-based resistance training (RT) and aerobic training (AT) during COVID-19 lockdowns. Secondary aims were to compare changes in body composition and physical function after 12 weeks between participants required to transition to home-based exercise (\"HOME\") and those who were able to continue gym-based exercise (\"GYM\").</p><p><strong>Methods: </strong>Thirty older adults (60-89 years) with obesity were enrolled from the gym-based HiRIT intervention arm of a 12-week exercise and dietary weight loss trial. Thirteen (43%) participants were transitioned to HOME due to COVID-19 lockdowns. HOME participants were prescribed bodyweight RT and AT exercises, while maintaining the weight loss intervention. Eight HOME participants completed semi-structured interviews post-intervention. Quantitative outcomes including exercise adherence, body composition and physical function were compared to GYM participants.</p><p><strong>Results: </strong>Participants' experiences and perspectives regarding the HOME program encompassed various elements including accessibility, accountability, maintaining physical activity levels, motivation, support from health care professionals, openness to telehealth videoconferencing for support, engagement, lack of equipment, supervision and a structured routine. Both groups had significant reductions in body mass (mean ± SD; GYM: -4.4 ± 0.4 kg, HOME: -6.2 ± 1.2 kg), but HOME demonstrated greater losses in fat mass (mean difference: -3.1 kg, 95% CI: -6.0, -0.3) compared with GYM represented by a large effect size (d = 0.8). Physical function outcomes improved only in GYM (all P < 0.05).</p><p><strong>Conclusions: </strong>Older adults with obesity transitioning from supervised gym-based to unsupervised home-based exercise face both supportive and challenging experiences. While accessibility and accountability enhanced their engagement, some participants faced difficulties related to limited equipment and digital support, emphasising areas for improvement in home-based exercise interventions. Home-based exercise may be effective for supporting dietary weight loss, but further research is needed to determine if there are any beneficial effects on physical function.</p><p><strong>Trial registration: </strong>Australian New Zealand Clinical Trials Registry (ANZCTR) ACTRN12618001146280; date of registration: 12/07/2018.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"556"},"PeriodicalIF":3.8,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144741146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The hidden burden of anemia in elderly surgical patients: a prospective study on incidence and contributing factors.","authors":"Habtie Bantider Wubet, Negesse Zurbachew Gobezie, Getachew Mekete Diress, Kumlachew Geta Belete, Kaletsidk Desalegn Mossie, Begizew Yimenu Mekuriaw, Abebe Dires Fenta, Alemie Fentie Mebratie, Kidist Hunegn Setargew, Temesgen Birlie Asmare","doi":"10.1186/s12877-025-06182-3","DOIUrl":"10.1186/s12877-025-06182-3","url":null,"abstract":"<p><strong>Background: </strong>Elderly surgical patients frequently experience anemia due to physiological changes, chronic comorbidities, and dietary deficiencies. Identifying associated risk factors is essential for improving surgical outcomes and reducing complications.</p><p><strong>Objective: </strong>To assess the incidence and determinants of anemia in elderly surgical patients at Debre Tabor Comprehensive Specialized Hospital in Ethiopia.</p><p><strong>Method: </strong>A prospective observational study was conducted from June 1, 2024, to February 30, 2025, involving elderly patients undergoing surgery at Debre Tabor Comprehensive Specialized Hospital. Anemia was diagnosed based on World Health Organization (WHO) criteria, with hemoglobin levels assessed both preoperatively and postoperatively. Multivariable logistic regression was used to analyze patient demographics, comorbidities, and surgical factors to identify predictors of anemia.</p><p><strong>Results: </strong>The incidence of anemia among elderly surgical patients was 64.8% (95% CI: 59.5-70.4%). Significant predictors included emergency surgery (AOR: 5.3, 95% CI: 3.2-8.3, p < 0.001), preexisting comorbidities (AOR: 2.5, 95% CI: 1.52-7.02, p < 0.001), blood loss > 500 mL (AOR: 9.8, 95% CI: 3.2-29.6, p < 0.001), polypharmacy (AOR: 4.8, 95% CI: 1.3-11.9, p < 0.001), major surgery (AOR: 3.9, 95% CI: 1.71-7.81, p < 0.001), and a history of previous surgeries (AOR: 7.7, 95% CI: 2.3-26.0, p < 0.001).</p><p><strong>Conclusion and recommendation: </strong>The incidence of anemia in elderly surgical patients at Debre Tabor Comprehensive Specialized Hospital is high and associated with several modifiable risk factors. Early detection and targeted preoperative optimization strategies are crucial for improving surgical outcomes in this population.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"555"},"PeriodicalIF":3.8,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144741148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between perceived neighborhood environment, sedentary behavior, walking, and moderate-to-vigorous physical activity and frailty: an isotemporal substitution model.","authors":"Hee-Kyoung Nam, Chang Won Won, Miji Kim, Sung-Il Cho","doi":"10.1186/s12877-025-06200-4","DOIUrl":"10.1186/s12877-025-06200-4","url":null,"abstract":"<p><strong>Introduction: </strong>With the rapid increases of older population and growing demand for longevity worldwide, frailty has become a major hurdle to sustaining healthy aging. As residential areas are the primary domains of mobility for older adults, the neighborhood environment is a crucial factor for their daily living and physical activity. This study aims to investigate whether replacing sedentary behavior with physical activity and having a supportive neighborhood environment are associated with frailty status in older adults.</p><p><strong>Methods: </strong>A cross-sectional analysis was conducted with 2,650 participants aged 70-84 years from the Korean Frailty and Aging Cohort Study (KFACS). The main explanatory variables included self-reported physical activity, sedentary behavior (SB), and perceived neighborhood environment. Frailty as the response variable was defined using the Fried frailty phenotype. Multinomial regression was performed to analyze the outcome. The Isotemporal Substitution Model (ISM) was applied to examine the effects of replacing sedentary behavior with physical activity.</p><p><strong>Results: </strong>The frailty status of participants was categorized as 45.3% robust, 47.3% pre-frail, and 7.6% frail. Accessibility factor was associated with a decreased risk of being pre-frail (odds ratio (OR): 0.750, 95% CI: 0.673-0.836) and frail (OR: 0.654, 95% CI: 0.541-0.789) compared to being robust. According to ISM, substituting 10 min of SB with any type of physical activity was associated with a reduced risk of pre-frailty [if 10 min of SB was replaced by 10 min of walking (OR: 0.972, CI: 0.960-0.985)] and frailty [if 10 min of SB was replaced by MVPA (OR: 0.877, CI: 0.836-0.921); or by walking (OR: 0.852, CI: 0.814-0.891)].</p><p><strong>Conclusions: </strong>Replacing SB with walking and improving neighborhood accessibility were significantly associated with reduced risk of being pre-frail or frail. These findings highlight the importance of considering these factors when designing age-friendly environments for older adults.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"558"},"PeriodicalIF":3.8,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144741134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}