BMC GeriatricsPub Date : 2025-07-15DOI: 10.1186/s12877-025-06181-4
Colleen Doyle, Sunil Bhar, Christina Bryant, Briony Dow, David Dunt, George Mnatzaganian, Daniel O'Connor, Julie Ratcliffe, Emily You, Anne-Marie Bagnall, Georgia Major, Robin Harper, Marcia Fearn
{"title":"Correction: BEFRIENding for depression, anxiety and social support in older adults living in Australian residential aged care facilities (BEFRIENDAS): randomised controlled trial protocol.","authors":"Colleen Doyle, Sunil Bhar, Christina Bryant, Briony Dow, David Dunt, George Mnatzaganian, Daniel O'Connor, Julie Ratcliffe, Emily You, Anne-Marie Bagnall, Georgia Major, Robin Harper, Marcia Fearn","doi":"10.1186/s12877-025-06181-4","DOIUrl":"10.1186/s12877-025-06181-4","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"529"},"PeriodicalIF":3.4,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC GeriatricsPub Date : 2025-07-14DOI: 10.1186/s12877-025-06116-z
Yazhou Liu, Ying Yang, Yuhao Li, Xiaodong Yang
{"title":"Association between preoperative persistent hyperglycemia and postoperative length of hospital in geriatric hip fracture patients.","authors":"Yazhou Liu, Ying Yang, Yuhao Li, Xiaodong Yang","doi":"10.1186/s12877-025-06116-z","DOIUrl":"10.1186/s12877-025-06116-z","url":null,"abstract":"<p><strong>Background: </strong>Metabolic disorders play a significant role in determining the length of hospital stay following hip fracture surgery in elderly patients. Therefore, it is crucial to conduct an in-depth investigation into the relationship between stress-induced hyperglycemia-one of the manifestations of metabolic disorders-and hospitalization duration in this patient population.</p><p><strong>Methods: </strong>This retrospective cohort study analyzed medical records of patients who underwent hip fracture surgery at a tertiary medical institution between January 2017 and November 2024. LASSO regression identified covariates for multivariate logistic regression. Propensity score matching minimized bias. Standardized mean differences assessed group balance. Logistic regression, restricted cubic splines, and dose-response analyses examined associations between blood glucose levels and LOS. Subgroup and threshold analyses evaluated robustness.</p><p><strong>Results: </strong>A total of 1,279 patients were included, with 673 (52.6%) having persistent preoperative hyperglycemia. The mean age was 74.7 ± 9.6 years, with 39.7% male and 60.3% female. Persistent hyperglycemia was significantly associated with prolonged LOS. Multivariate logistic regression showed a 12% increase in LOS for each unit increase in preoperative glucose (OR = 1.12, 95% CI: 1.07-1.18). Propensity score matching confirmed this association, with a significant linear trend (P < 0.001). Subgroup analyses revealed interactions with gender, hypertension, cerebrovascular disease, and diabetes mellitus.</p><p><strong>Conclusion: </strong>Preoperative blood glucose levels are significantly associated with prolonged LOS in elderly hip fracture patients, showing a nonlinear dose-response relationship. Each 1 mmol/L increase in glucose raises LOS risk by 12%, with stronger correlations in females and diabetics. Timely intervention is critical above 6.16 mmol/L.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"527"},"PeriodicalIF":3.4,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257712/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC GeriatricsPub Date : 2025-07-14DOI: 10.1186/s12877-025-06147-6
Zhaohua Huo, Benjamin Hon-Kei Yip, Allen Ting-Chun Lee, Sheung-Tak Cheng, Wai Chi Chan, Ada Wai-Tung Fung, Suk Ling Ma, Calvin Pak-Wing Cheng, Frank Ho-Yin Lai, Samuel Yeung-Shan Wong, Linda Chiu-Wa Lam
{"title":"Moderating role of positive aspects of caregiving in the relationship between caring burden and suicidal ideation in family caregivers of community-dwelling older adults with neurocognitive disorders.","authors":"Zhaohua Huo, Benjamin Hon-Kei Yip, Allen Ting-Chun Lee, Sheung-Tak Cheng, Wai Chi Chan, Ada Wai-Tung Fung, Suk Ling Ma, Calvin Pak-Wing Cheng, Frank Ho-Yin Lai, Samuel Yeung-Shan Wong, Linda Chiu-Wa Lam","doi":"10.1186/s12877-025-06147-6","DOIUrl":"10.1186/s12877-025-06147-6","url":null,"abstract":"<p><strong>Background: </strong>Psychological distress is common in family caregivers of individuals with neurocognitive disorders (NCDs). This study examined the prevalence of suicidal ideation in this population, and explored the moderating role of positive aspects of caregiving (PAC) in mitigating such severe psychological difficulties.</p><p><strong>Methods: </strong>445 older adults (NCDs: 322, normal cognition: 123) and their family caregivers were recruited from the population-based Hong Kong Mental Morbidity Survey for Older Persons. Caregivers' suicidal ideation was screened by positive response to Item 9 of the Patient Health Questionnaire-9: thoughts of being better off dead or self-harm in the past two weeks. PAC were measured using a validated scale. A conceptual model was developed to test the mediation and moderation effects among caregiving burden, psychological distress, suicidal ideation, and PAC.</p><p><strong>Results: </strong>Nearly one in ten (9%) dementia caregivers reported suicidal ideation in the past two weeks. Higher prevalence was observed among female carers, those with comorbid mood disorders, and those caring for individuals with high comorbidity or functional dependence. Psychological distress significantly mediated the relationship between caregiving burden and suicidal ideation (80.5%, p = 0.023). PAC moderated this pathway: higher levels of PAC were associated with reduced suicidal ideation among carers with moderate-to-high caregiving burden (p < 0.05). However, a rebound in suicidal ideation was observed in caregivers experiencing both high burden and high PAC.</p><p><strong>Conclusions: </strong>Suicidal ideation among NCD caregivers is closely linked to caregiving burden and psychological distress. PAC plays a complex and non-linear moderating role in this relationship. Psychological intervention that strengthens PAC should be integrated into comprehensive caregiver support programmes, particularly for those experiencing high burden and high distress.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"524"},"PeriodicalIF":3.4,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC GeriatricsPub Date : 2025-07-14DOI: 10.1186/s12877-025-06162-7
Pingfeng He, Yaling Li, Fu Ding, Xintong Liu, Qiumei Lin
{"title":"Prevalence and risk factors of sarcopenic dysphagia in elderly hospitalized patients: a retrospective cohort study based on data from a comprehensive geriatric assessment system.","authors":"Pingfeng He, Yaling Li, Fu Ding, Xintong Liu, Qiumei Lin","doi":"10.1186/s12877-025-06162-7","DOIUrl":"10.1186/s12877-025-06162-7","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"525"},"PeriodicalIF":3.4,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relationship between illness perception and quality of life among Chinese rural elderly patients with hypertension: the mediating role of medication experience.","authors":"Ziyuan Li, Xiaona Li, Wenqiang Yin, Min Gao, Ping Dong, Yongli Shi, Zhaofeng Yu, Zhiqiang Feng, Zhongming Chen","doi":"10.1186/s12877-025-06184-1","DOIUrl":"10.1186/s12877-025-06184-1","url":null,"abstract":"<p><strong>Objective: </strong>A significant correlation has been discovered between illness perception and quality of life, but the relationships among illness perception, medication experience, and quality of life remain to be confirmed. Therefore, this study aims to identify the relationship between illness perception and quality of life among Chinese rural elderly patients with hypertension and to analyse the possible mediating role of medication experience between these two aspects.</p><p><strong>Methods: </strong>From September to December 2023, a cross-sectional study was conducted to select rural elderly patients with hypertension by multi-stage stratified random sampling. Data was collected using the brief illness perception questionnaire, the grassroots medication experience scale for patients with chronic diseases and the quality of life scale. Multiple linear regression and Bootstrap method were used to explore the mediating role of medication experience between illness perception and quality of life.</p><p><strong>Results: </strong>A total of 846 patients met the inclusion criteria. The mean scores of illness perception, medication experience and quality of life at baseline were 4.85 ± 1.04, 4.13 ± 0.52, 4.37 ± 0.37, respectively. The result of Spearman correlation analysis showed that the illness perception was negatively correlated with medication experience (r = -0. 359, P < 0.01) and quality of life (r = -0. 317, P < 0.01), and medication experience was positively correlated with quality of life (r = 0. 511, P < 0.01). The results of mediating effect test indicate that medication experience had a partial mediating effect on the relationship between illness perception and quality of life among rural elderly hypertensive patients, and the mediating effect accounted for 54.21%.</p><p><strong>Conclusions: </strong>Our findings revealed that illness perception not only directly influenced quality of life among rural elderly hypertensive patients but also indirectly via medication experience. Illness perception is a negative factor affecting the quality of life of rural elderly patients with hypertension, while medication experience is a protective factor. Therefore, medical institutions should strengthen health education to improve their illness perception of hypertension. The pharmaceutical service ability of rural medical institutions should be improved to improve the medication experience of hypertensive patients.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"523"},"PeriodicalIF":3.4,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The association between dual sensory impairment and social participation among older adults in China: a moderated mediation model of activities of daily living and depressive symptoms.","authors":"Lunxin Liu, Zhenglin Cao, Qingshan Ma, Zhiliu Liao","doi":"10.1186/s12877-025-06173-4","DOIUrl":"10.1186/s12877-025-06173-4","url":null,"abstract":"<p><strong>Background: </strong>While dual sensory impairment (DSI) is known to reduce social participation (SP) in older adults, the underlying mechanisms remain unclear. Therefore, the aim of this study was to ascertain: (1) whether ADL mediates the relationship between DSI and SP, and (2) how depressive symptoms modify the mediation pathway - questions essential for developing targeted interventions.</p><p><strong>Methods: </strong>In the 2018 wave of the China Health and Retirement Longitudinal Study (CHARLS), 8,270 older individuals (60 years of age or older) were enrolled. We examined a mediation model first, where ADL was a mediator between DSI and SP. Furthermore, depressive symptoms were integrated into the model as moderator in the correlation between DSI and ADL. The PROCESS macro was used to analyze the mediation and moderated mediation models.</p><p><strong>Results: </strong>In older people, DSI correlated negatively with SP, and ADL partially mediated this association (B = -0.019, 95% CI = -0.025, -0.015) with an intermediary effect of 14.6%. Besides, the relationship between DSI and ADL was moderated by depressive symptoms (B = 0.092, 95% CI = 0.060, 0.123), and ADL was more affected by DSI in older adults who experienced higher levels of depressive symptoms.</p><p><strong>Conclusions: </strong>Depressive symptoms moderated the mediation of ADL on an indirect, negative correlation between DSI and SP. The findings contribute to existing knowledge by illustrating the fundamental mechanisms connecting DSI and SP. These Findings highlight the need for integrated interventions targeting both sensory impairment and mental health to mitigate SP decline in aging populations.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"526"},"PeriodicalIF":3.4,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257664/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Independent and joint associations of physical activity and a body shape index with sleep disorders in older adults with cardiometabolic multimorbidity: a cross-sectional study.","authors":"Yang Li, Huiqian Zhou, Dandan Xu, Hua Wang, Yutong Zhao, Hua Jiang","doi":"10.1186/s12877-025-06170-7","DOIUrl":"10.1186/s12877-025-06170-7","url":null,"abstract":"<p><strong>Background: </strong>Cardiometabolic multimorbidity (CMM) has become a significant public health challenge in the context of global ageing. Sleep disorders are prevalent in older adults with CMM, but their correlations with physical activity and a body shape index (ABSI) remain unclear. This study aimed to investigate the independent and joint associations of physical activity and ABSI with sleep disorders in older adults with CMM.</p><p><strong>Methods: </strong>This cross-sectional study was conducted between February and March 2024 and recruited 650 older CMM patients (aged ≥ 65 years) by random sampling. Data were collected using a structured questionnaire as well as the Pittsburgh Sleep Quality Index (PSQI) and the International Physical Activity Questionnaire-short form (IPAQ-SF). Logistic regression models were used to assess the independent and joint associations of physical activity and ABSI with sleep disorders.</p><p><strong>Results: </strong>The prevalence of sleep disorders among older CMM patients was 48.46%, and low IPAQ (OR = 3.61, 95%CI: 2.41 to 5.43) and high ABSI (OR = 1.46, 95%CI: 1.04 to 2.04) were identified as independent risk factors for sleep disorders. The risk of sleep disorders in patients with low IPAQ and high ABSI group was approximately 5.1 times higher than that in patients with middle/high IPAQ and low ABSI group (OR = 5.10, 95% CI: 2.88 to 9.02). The stratified analyses indicated that these relationships were particularly pronounced in the > 70 years and female subgroups.</p><p><strong>Conclusion: </strong>This study highlights the important impact of physical activity and body shape management on sleep disorders in older CMM patients.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"519"},"PeriodicalIF":3.4,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12254990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144616163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC GeriatricsPub Date : 2025-07-12DOI: 10.1186/s12877-025-06016-2
Gideon Dzando, Paul R Ward, Lillian Mwanri, Richard K Moussa, Rachel C Ambagtsheer
{"title":"Association between frailty and quality of life, and the moderating effect of mobile, broadcast and digital media in sub-Saharan Africa: evidence from Kenya.","authors":"Gideon Dzando, Paul R Ward, Lillian Mwanri, Richard K Moussa, Rachel C Ambagtsheer","doi":"10.1186/s12877-025-06016-2","DOIUrl":"10.1186/s12877-025-06016-2","url":null,"abstract":"<p><strong>Background: </strong>Globally, frailty is known to negatively impact quality of life, yet this relationship remains underexplored in Kenya. Additionally, there is growing interest in leveraging technology in health and social care to support vulnerable populations, but its potential benefits for older people remain unclear. This study aimed to examine the association between frailty and quality of life, and to explore the moderating role of mobile, broadcast, and digital media in the relationship between frailty and quality of life among older people.</p><p><strong>Methods: </strong>This study involved 783 older people (aged 60 years and above) who participated in the Health and Well-being of Older Persons in Kenya (HWOPs-1) study. Frailty was assessed using a 32-item Frailty Index, and quality of life was measured using a 7-item index from the World Health Organization's Quality of Life-Brief instrument. Bivariate analysis was conducted to examine associations between frailty, quality of life, and access to mobile, broadcast, and digital media. Multiple moderation regression analysis was used to estimate whether media access (radio, television, mobile phone ownership, and internet usage) influenced the relationship between frailty and quality of life by including interaction terms between frailty and each media variable.</p><p><strong>Results: </strong>More than half (66.0%) of the study participants were frail, and 82.9% had moderate to good quality of life. Frailty was inversely correlated with quality of life (r = -0.61, p < 0.001), indicating that higher levels of frailty are associated with poorer quality of life. The mobile, broadcast and digital media variables were all positively correlated with frailty (r = 0.121 to 0.330, p < 0.001) and negatively correlated with quality of life (r = -0.24 to -0.12, p < 0.001). The moderation analysis revealed that only mobile phone ownership showed a significant moderation effect (β = 1.10, p = 0.03, 95% CI [0.12, 2.08]), suggesting that access to mobile phones may help mitigate the impact of frailty on quality of life.</p><p><strong>Conclusion: </strong>Frailty significantly impacts quality of life. Access to mobile phones may help mitigate this effect by fostering social connectedness, while introducing complex technologies may be counterproductive in improving frailty-associated quality of life.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"521"},"PeriodicalIF":3.4,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12255119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144616156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC GeriatricsPub Date : 2025-07-12DOI: 10.1186/s12877-025-06178-z
Yen-Huai Lin, Michael Mu Huo Teng
{"title":"Central obesity is more strongly associated with vertebral fractures than general obesity: a cross-sectional study.","authors":"Yen-Huai Lin, Michael Mu Huo Teng","doi":"10.1186/s12877-025-06178-z","DOIUrl":"10.1186/s12877-025-06178-z","url":null,"abstract":"<p><strong>Background: </strong>Both general and central obesity have been linked to vertebral fractures; however, their specific effects on vertebral fractures have not been directly compared. This study aimed to investigate the associations between measures of general and central obesity and vertebral fractures.</p><p><strong>Methods: </strong>This cross-sectional study of 1,011 postmenopausal women used dual-energy X-ray absorptiometry to measure bone density and body composition. Bone quality was assessed using the trabecular bone score. General obesity was evaluated using body mass index and body fat percentage, whereas central obesity was measured using waist circumference, waist-hip ratio, and android-gynoid ratio. Vertebral fractures were determined by retrospectively reviewing medical records, and only fractures confirmed by radiological reports were included.</p><p><strong>Results: </strong>Obesity indices, including body mass index, body fat percentage, waist circumference, and android-gynoid ratio, were positively associated with bone density but negatively associated with trabecular bone score. General obesity, based on body fat percentage, was associated with vertebral fractures, whereas general obesity measured using body mass index was not. Central obesity assessed using waist circumference, waist-hip ratio, and android-gynoid ratio, was associated with vertebral fractures. Furthermore, among the different combinations of general and central obesity, central obesity measured by waist circumference and waist-hip ratio was still associated with vertebral fractures, irrespective of general obesity.</p><p><strong>Conclusions: </strong>Central obesity was more strongly associated with vertebral fractures than general obesity in postmenopausal women. Therefore, developing and implementing measures to prevent central obesity are recommended.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"522"},"PeriodicalIF":3.4,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12255142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144616158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between sarcopenia and postoperative delirium in elderly surgical patients: a systematic review and meta-analysis.","authors":"Yunying Feng, Ruixiao Sun, Yuelun Zhang, Lulu Ma, Yuguang Huang, Kang Yu","doi":"10.1186/s12877-025-06183-2","DOIUrl":"10.1186/s12877-025-06183-2","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenia, characterized by the progressive loss of muscle mass and strength, is common in the elderly and significantly increases the risk of poor postoperative outcomes. This study aims to examine the impact of sarcopenia on postoperative delirium and a range of perioperative outcomes in elderly patients.</p><p><strong>Methods: </strong>A systematic search was conducted in MEDLINE, EMBASE, CINAHL, and Cochrane CENTRAL. Studies investigating the association between sarcopenia and postoperative complications in elderly surgical patients were included. The Quality in Prognosis Studies (QUIPS) tool was utilized for risk-of-bias assessment. The primary outcome was the incidence of postoperative delirium. Secondary outcomes included other postoperative complications and further recovery. Subgroup analyses were conducted based on surgery types.</p><p><strong>Results: </strong>A total of 10,981 records were identified, with 265 studies included in the systematic review and 242 in the final meta-analysis. A significant association was found between sarcopenia and postoperative delirium in both univariable and multivariable analyses (univariable: OR 1.81, 95% confidence interval [CI] 1.31 to 2.50, P < 0.001, I<sup>2</sup> 24.0%; multivariable: OR 2.42, 95% CI 1.27 to 4.59, P = 0.007, I<sup>2</sup> 0.0%). Sarcopenia was also associated with adverse postoperative outcomes, including increased complications, mortality, delayed recovery, and reduced overall survival. However, no significant associations were observed for postoperative pancreatic fistula or recurrence. Syntheses of multivariable analyses showed significant differences in postoperative complications, mortality, overall survival, and recurrence. Subgroup analyses indicated a higher risk of reduced overall survival among sarcopenic patients undergoing head and neck or heart and chest surgeries.</p><p><strong>Conclusions: </strong>Sarcopenia is a strong independent predictor of postoperative delirium and poor postoperative outcomes in elderly surgical patients.</p><p><strong>Systematic review registration: </strong>PROSPERO registration number CRD42023424696 (18 May 2023).</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"520"},"PeriodicalIF":3.4,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12255066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144616157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}