BMC Geriatrics最新文献

{"title":"Cancer-related identity and advanced old age - analysis of prostate cancer survivors after radical prostatectomy over the age of 75.","authors":"Matthias Jahnen, Charlotte Bierwirth, Valentin H Meissner, Andreas Dinkel, Stefan Schiele, Helga Schulwitz, Jürgen E Gschwend, Kathleen Herkommer","doi":"10.1186/s12877-025-06477-5","DOIUrl":"10.1186/s12877-025-06477-5","url":null,"abstract":"<p><strong>Background: </strong>The struggle to incorporate the experience of suffering from PCa in their biography can be evident in men affected by PCa even years after the initial cancer diagnosis. Aim of this study was to assess the cancer-related identity and associated factors in men over 75 years affected by PCa and treated with radical prostatectomy to improve the understanding of cancer-related self-perception in older men.</p><p><strong>Methods: </strong>2,379 on average 82.2 ± 3.9 year-old prostate cancer survivors with a mean follow-up of 17.9 ± 3.7 after radical prostatectomy were asked to choose one of 5 cancer-related identities (\"patient\", \"victim\", \"someone who has had cancer\", \"cancer survivor,\" and \"cancer conqueror\"). Associations with clinical data, aging-related factors (frailty, comorbidities, loneliness), and psychological factors were assessed.</p><p><strong>Results: </strong>Most men identified with the neutral terms \"someone who has had cancer\" (45.7%) and patient (27.0%), which was associated with primarily clinical characteristics. Identification with negatively connoted cancer-related identities was less common (\"cancer survivor\" (15.7%), \"victim\" (2.1%)) and was associated with primarily aging-related and psychological factors. Identification as a \"cancer survivor\" was associated with more self-reported comorbidities (OR: 1.09 [1.01 - 1.17]) and symptoms of depression (OR: 1.71 [1.20 - 2.45]). Identification as a victim was associated with severe loneliness (OR: 5.09 [2.39 - 10.85]). The positively connoted cancer-related identity \"cancer conqueror\" (9.5%) was associated with a higher quality of life (OR: 1.41 [1.28 - 1.57]).</p><p><strong>Conclusions: </strong>The cancer-related identity in long-term PCa survivors of advanced old age varies widely. Especially negatively connoted cancer-related identities reflect the subjective disease experience, the overall health status, and the lack of a social support system. Even years after the primary diagnosis and treatment, assessment of the cancer-related identity can identify men who are affected most by their cancer experience and might need further psycho-oncological assistance.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"759"},"PeriodicalIF":3.8,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12502345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Living well with dementia: a qualitative interview study on family caregivers' call for more person- and family-centered dementia support.","authors":"Pia Bastholm-Rahmner, Katharina Schmidt-Mende, Karin Modig, Monica Bergqvist","doi":"10.1186/s12877-025-06429-z","DOIUrl":"10.1186/s12877-025-06429-z","url":null,"abstract":"<p><strong>Background: </strong>Family members are often the primary caregivers for individuals with dementia, but they face significant challenges in navigating health care and social services, especially as the disease progresses. Many caregivers experience loneliness, social isolation, and stress from sacrificing their own well-being. This study aimed to describe the daily experiences of family caregivers of individuals with dementia, with the objective of better understanding and addressing their specific needs.</p><p><strong>Methods: </strong>Qualitative interviews with 11 family caregivers in Sweden. Data were analyzed by inductive thematic analysis.</p><p><strong>Results: </strong>Three themes were identified: (1) Struggling with conflicting emotions and social challenges - caregivers reported experiencing stress, physical exhaustion, and emotional strain due to constant availability and the challenges of managing behavioral changes, further intensified by isolation and shrinking social networks. (2) Balancing autonomy in care decisions - caregivers described the paradox of bearing full responsibility for care decisions despite having limited access to information, and, (3) Dependence on home care and nursing homes that are not adapted to needs - caregivers expressed a reliance on home care and nursing homes, yet noted that these services are often ill-equipped to address the specific demands of dementia care.</p><p><strong>Conclusion: </strong>Caring for a family member with dementia reshapes family roles and creates ongoing challenges in balancing safety, well-being, and limited support. This study highlights the need for person- and family-centered care, grounded in the home context and developed in partnership with family caregivers. Improved coordination, trained staff, and supportive policies are essential, alongside continued conceptual development to define best practices in dementia care.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"758"},"PeriodicalIF":3.8,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12502536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145237937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of intrinsic capacity impairment and associated factors among retired older people in Cameroon.","authors":"Marie-Josiane Ntsama Essomba, Joel Kevin Andela Ebidiye, Jean Jacques Noubiap, Jules Motto Ndoumbe, Félicité Djuikwo Teukeng, Maturin Tabue Teguo","doi":"10.1186/s12877-025-06421-7","DOIUrl":"10.1186/s12877-025-06421-7","url":null,"abstract":"<p><strong>Background: </strong>Early identification of older adults at increased risk for functional decline remains challenging in the majority of African countries. We aimed to determine the prevalence of intrinsic capacity (IC) impairment and associated factors among a group of retired Cameroonians.</p><p><strong>Methods: </strong>This cross-sectional study included retired individuals aged 60 years or older. We collected sociodemographic data and geriatric syndromes. The Integrated Care to Older People (ICOPE) screening tool was used to assess the domains of IC. Multivariable regression analysis was used to assess factors associated with IC impairment.</p><p><strong>Results: </strong>A total of 375 older adults underwent baseline step 1 screening (42.7% Male; mean age 67.9 ± 6.03 years), of whom 356 (94.9%) had a positive result. Step 2 assessment was conducted in 281 participants (78.9%), confirming IC impairment in 182 individuals (48.5%). The most frequently impaired domains were cognition (49.8%), vision (44.8%), and hearing (43.1%). In univariable analysis, participants with IC impairment were more likely to be older (mean age 69.03 ± 6.58 vs. 66.8 ± 5.04 years; p = 0.037), have lower educational level (p< .001), report comorbidities (p =.031), a history of falls (p = .035), and sleep disorders (p = 0.019). Male participants were more likely to have preserved IC compared to females (p =.033). After adjusting for age and sex, factors associated with IC impairment included low educational level [odds ratio (OR) 3.04; 95% confidence interval (CI): 1.4-6.7], history of falls (OR 4.02; 95% CI: 1.11-14.6), and sleep disorders (OR 2.9; 95% CI: 1.4-6.2).</p><p><strong>Conclusion: </strong>Identification of older at risk of IC impairment in Cameroon may help tailor further policies for Healthy Aging taking into account available resources.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"760"},"PeriodicalIF":3.8,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12502386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145237975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The SUGAR handshake intervention to prevent hypoglycaemia in elderly people with type 2 diabetes: process evaluation within a pragmatic randomised controlled trial.","authors":"Huda Y Almomani, Helen M Ayre, Richard A Powell, Keivan Armani","doi":"10.1186/s12877-025-06361-2","DOIUrl":"10.1186/s12877-025-06361-2","url":null,"abstract":"<p><strong>Background: </strong>The SUGAR Handshake is a pharmacist-led educational intervention to prevent hypoglycaemia in elderly people with type 2 diabetes mellitus (T2DM). A process evaluation was conducted alongside the ROSE-ADAM pragmatic randomized controlled trial (RCT) to assess the implementation of the intervention and study procedures, explore mechanisms of impact, and examine future scalability.</p><p><strong>Methods: </strong>This mixed-methods process evaluation was nested within a single-centre RCT conducted at outpatient clinics in a Jordanian hospital. Routine monitoring quantitative data assessed adherence to the intervention components and study activities, and estimated reach. Qualitative data, collected through semi-structured interviews with 12 purposively selected participants on Days 45 and 90 of enrolment, captured experiences with the intervention and usual care. Thematic analysis was used for qualitative data; descriptive statistics and inferential tests were applied to quantitative data.</p><p><strong>Results: </strong>The intervention was well implemented: 104 of 106 participants (98.11%) continued the full intervention, with a 100% reach to those enrolled in the trial. Participants showed high adherence to study activities (mean ± SD: 88.07 ± 9.33 documented days on diaries; 77.97 ± 18.87 fasting blood glucose measurements). Intervention reach was 100%. Participants described the intervention as informative, easy to follow, and helpful in avoiding hypoglycaemia and the side-effects of antidiabetic medications. Key facilitators included trust in pharmacists, altruism, and social support. Reported barriers were people's health status, age-related conditions, and stress.</p><p><strong>Conclusions: </strong>This process evaluation highlights the SUGAR Handshake's potential for broader implementation and scale-up. By addressing identified barriers, future educational interventions may enhance adherence, improve patient outcomes, and advance hypoglycaemia management in diabetes care.</p><p><strong>Trial registration: </strong>Clinicaltrials.gov (NCT04081766), registration date 4,920,219.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"753"},"PeriodicalIF":3.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of Geriatric Nutritional Risk Index in predicting adverse outcomes in patients with bloodstream infections: a retrospective study.","authors":"Xin-Lou Li, Zheng-Hao Yu, Wu-Hong Zhou, Yan-Ling Bai, Bo-Wei Liu, Xiao-Ming Zhang, Huan Li, Jia-Xi Li, Cheng-Xue Ma, Ming-Mei Du, Yun-Xi Liu, Meng-Lin Liu, Hong-Wu Yao","doi":"10.1186/s12877-025-06387-6","DOIUrl":"10.1186/s12877-025-06387-6","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"754"},"PeriodicalIF":3.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of Ishii test for sarcopenia in older patients with knee osteoarthritis.","authors":"Nanyan Li, Guangyuan Dong, Yun Lu, Pingjuan Tan, Jingchun Zhang, Qingzhao Liang, Shiqi Gong, Mengchao He, Yifei Wang, Lei Shi","doi":"10.1186/s12877-025-06343-4","DOIUrl":"10.1186/s12877-025-06343-4","url":null,"abstract":"<p><strong>Background: </strong>Knee osteoarthritis is becoming increasingly common, and the age-related decline in muscle mass or sarcopenia can exacerbate both conditions in a vicious cycle. Therefore, screening for sarcopenia is crucial for the management of both diseases. The Ishii score as an effective screening tool is currently widely used.</p><p><strong>Objectives: </strong>This study aimed to validate the predictive effectiveness of the Ishii test in older adults with knee osteoarthritis patients, establish new cut-off value to assess its accuracy in predicting sarcopenia.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted on 404 participants with knee osteoarthritis from China. Patients with sarcopenia were identified according to the 2019 criteria of the Asian Working Group for Sarcopenia. Social demographic variables, body composition, handgrip strength and calf circumference were collected and the Ishii score was calculated. The accuracy of the Ishii score test was determined by using indicators, including specificity, sensitivity, negative and positive predictive values, negative and positive likelihood ratios, Kappa value, Youden index, and receiver operating characteristic curve.</p><p><strong>Results: </strong>The Ishii test predicts sarcopenia at an AUC value of 0.85 for males, and at an AUC value of 0.84 for females. The cut-off value is over 108 for males and 119 for females, with the new cut-off value, the sensitivity, specificity, positive and negative predictive values, the kappa value or sarcopenia were 0.95, 0.66, 0.47, 0.98, 0.45 for males, and 0.91, 0.73, 0.47, 0.97,0.48 for females, respectively.</p><p><strong>Conclusions: </strong>The study validated that the Ishii test can serve as a practical screening tool in community or clinical settings.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"755"},"PeriodicalIF":3.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in service use and unmet needs in home- and community- based services in the United States during the COVID-19 pandemic.","authors":"Romil R Parikh, Tetyana P Shippee, Jack M Wolf, Benjamin Langworthy, Chanee D Fabius, Janette Dill, Dana Urbanski, Stephanie Giordano, Eric Jutkowitz","doi":"10.1186/s12877-025-06396-5","DOIUrl":"10.1186/s12877-025-06396-5","url":null,"abstract":"<p><strong>Background: </strong>More than 4 million older adults in the United States use publicly funded home-and community-based services (HCBS) which were disrupted during the COVID-19 pandemic. There is paucity of empirical evidence of how service disruptions influenced consumer needs in different types of HCBS. Therefore, we evaluate changes in service use and consumer-reported unmet service needs in HCBS during the COVID-19 pandemic (2021-2022) versus pre-pandemic (2018-2019), to inform future public health emergency (PHE) preparedness.</p><p><strong>Methods: </strong>We analyzed repeated cross-sectional survey data from the National Core Indicators- Aging and Disability Adult Consumer Survey in two survey waves, 2018-2019 and 2021-2022. We included community-dwelling, older HCBS consumers (age ≥ 65 years; n = 7143) from 11 states that participated in both survey waves. We measured service use and consumer-reported unmet needs as outcomes for six commonly used HCBS including personal care, homemaker, meal delivery, adult day, transportation, and caregiver respite/support. Using logistic regression, we calculated adjusted odds ratios (aOR) and 95% confidence interval (CI) to evaluate changes in outcomes during versus pre-pandemic, adjusting for demographics, health-related variables, and self- versus proxy-response, with random intercepts for each state.</p><p><strong>Results: </strong>Compared to 2018-2019, during 2021-2022, odds of service use increased for personal care (aOR, 1.24; 95% CI, 1.09, 1.40) and caregiver respite/support (aOR, 1.28; 95% CI, 1.00, 1.63) but decreased for homemaker services (OR, 0.69; 95% CI, 0.60, 0.79) and meal delivery (aOR, 0.81; 95% CI, 0.70, 0.93). During the PHE, odds of unmet service needs increased for personal care (aOR, 1.23; 95% CI, 1.03, 1.46) and meal delivery (aOR, 1.26; 95% CI, 1.01, 1.56), and decreased for caregiver respite/support (aOR, 0.49; 95% CI, 0.35, 0.70).</p><p><strong>Conclusions: </strong>During the PHE, simultaneous increase in services use and unmet service needs for some HCBS (e.g. personal care) suggests that temporary PHE measures taken were insufficient to offset the demand for those services. For caregiver respite/support, increased service use and decreased unmet service needs suggests that the temporary PHE measures for caregiver support may have offset a rise in service demand. These findings can inform evaluations of temporary PHE policies for HCBS and disaster preparedness efforts for future PHEs.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"733"},"PeriodicalIF":3.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between cognitive impairment and quality of life in rural older adults with chronic diseases-parallel mediating effects of depressive symptoms and frailty.","authors":"Haoqi Li, Mengyuan Xu, Wenqiang Yin, Xianglan Zhuge, Ping Dong, Yongli Shi, Ziyuan Li, Xianqi Zhang, Jianwei Wang, Zhongming Chen","doi":"10.1186/s12877-025-06446-y","DOIUrl":"10.1186/s12877-025-06446-y","url":null,"abstract":"<p><strong>Background: </strong>Cognitive impairment among older adults is a significant public health concern worldwide. Although previous studies have demonstrated that cognitive impairment impacts the quality of life in these patients, the mechanism between these two variables is still unclear. This study endeavors to investigate the parallel mediating roles of depressive symptoms and frailty on cognitive impairment and quality of life in rural older adults with chronic diseases.</p><p><strong>Methods: </strong>This study used data from a cross-sectional study conducted in rural areas of China from October 2024 to January 2025. A total of 2,697 rural older adults With chronic diseases were included. All data were analyzed using SPSS 26.0 software. Spearman correlation analysis Was used to investigate the relationships between variables. Model 4 from the SPSS macro was used to assess the parallel mediating roles of depressive symptoms and frailty in the relationship between cognitive impairment and quality of life among rural older adults with chronic diseases.</p><p><strong>Results: </strong>Cognitive impairment, depressive symptoms, and frailty were significantly associated with quality of life in rural older adults with chronic diseases (p < 0.01). Cognitive impairment was a negative predictor of quality of life (β = -0.2300, p < 0.001). Cognitive impairment was a positive predictor of depressive symptoms (β = 0.2881, p < 0.001) and frailty (β = 0.2275, p < 0.001). Cognitive impairment (β = -0.0964, p < 0.001), depressive symptoms (β = -0.2144, p < 0.001), and frailty (β = -0.3157, p < 0.001) were negative predictors of quality of Life. Cognitive impairment influenced quality of Life through parallel mediating effects of depressive symptoms and frailty, With mediating effects accounting for 26.85% and 31.48% of the total effect, respectively.</p><p><strong>Conclusions: </strong>We found that cognitive impairment not only directly affects the quality of life of rural older adults with chronic diseases but also indirectly affects them through depressive symptoms and frailty. To improve the quality of life of rural older adults with chronic diseases, we should pay attention to their cognitive impairment. Simultaneously, efforts should focus on alleviating depressive symptoms and frailty in this population. Strengthening the management of chronic diseases is also essential. These steps will help us achieve the goal of healthy aging.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"747"},"PeriodicalIF":3.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12482007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct and indirect associations of stress hyperglycemia with delirium in older adults with community-acquired pneumonia: limited mediation by neutrophil-lymphocyte ratio and procalcitonin.","authors":"Jingxian Liao, Xiaozhu Shen, Zhiqiang Du, Lei Miao","doi":"10.1186/s12877-025-06410-w","DOIUrl":"10.1186/s12877-025-06410-w","url":null,"abstract":"<p><strong>Background: </strong>Stress hyperglycaemia is common among older adults hospitalised with community-acquired pneumonia (CAP) and is associated with delirium; however, the underlying inflammatory pathways remain unclear. We investigated whether the neutrophil-to-lymphocyte ratio (NLR) and procalcitonin (PCT) mediate the relation between the stress-hyperglycaemia ratio (SHR) and delirium.</p><p><strong>Methods: </strong>This single-centre retrospective cohort included 412 patients aged ≥ 65 years admitted for CAP. Delirium was assessed daily with the Confusion Assessment Method. Logistic regression models yielded odds ratios (ORs) for delirium, whereas linear regression models for NLR and PCT provided standardised beta coefficients (β_std). All continuous variables (SHR, NLR and PCT) were z-scored prior to mediation analysis.</p><p><strong>Results: </strong>Delirium developed in 99 patients (24.0%). After adjustment for age, sex and comorbidities, SHR (OR = 9.13, 95% CI 4.44-18.96), NLR (OR = 1.12 per unit, 95% CI 1.06-1.19) and PCT (OR = 1.14 per ng/mL, 95% CI 1.06-1.21) were independent predictors of delirium. The total standardised effect of SHR on delirium was β_std = 0.321, of which 80.6% was direct (β_std = 0.259, 95% CI 0.149-0.427). The NLR-mediated pathway accounted for 19.4% of the association (β_std = 0.062, 95% CI 0.024-0.107). Pathways involving PCT-alone or in sequence with NLR-were not significant.</p><p><strong>Conclusions: </strong>In older CAP patients, stress hyperglycaemia substantially elevates delirium risk, predominantly through a direct mechanism only partly (≈ 20%) mediated by systemic inflammation reflected by NLR. Prompt detection and management of acute hyperglycaemia may therefore offer a practical approach to delirium prevention. Prospective multicentre studies are needed to confirm causality and to test glucose- and inflammation-modulating interventions.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"735"},"PeriodicalIF":3.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12482508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between nutritional status and mental health among elderly in community health screenings: a cross sectional study.","authors":"Nurliana Abd Nassir, Siti Sara Yaacob, Noor Azleen Ahmad Tarmizi, Khairatul Nainey Kamaruddin, Nur Amirah Shibraumalisi","doi":"10.1186/s12877-025-06394-7","DOIUrl":"10.1186/s12877-025-06394-7","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"739"},"PeriodicalIF":3.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12482607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}