BMC Geriatrics最新文献

{"title":"Sarcopenia and sleep duration with the likelihood of successful aging among older adults in China: a prospective cohort study.","authors":"Bo Liang, Dingchun Hou, Jiajia Li, Gong Chen, Lijun Pei","doi":"10.1186/s12877-025-06360-3","DOIUrl":"10.1186/s12877-025-06360-3","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenia and sleep duration have emerged as crucial health-related factors in geriatric research. This study aimed to investigate the independent and joint associations of sarcopenia and sleep duration with successful aging and its components among older adults in China.</p><p><strong>Methods: </strong>A dynamic 10-year cohort of 6,410 adults aged ≥ 60 was constructed using the China Health and Retirement Longitudinal Study (CHARLS) data (2011-2020). Sarcopenia was identified using the Asian Working Group for Sarcopenia (AWGS) 2019 criteria. Sleep duration encompassed nighttime sleep and naps. Cox proportional hazards regression and multivariable logistic regression were used to examine the associations. Sensitivity analyses were conducted using alternative definitions of successful aging and applying generalized linear mixed models.</p><p><strong>Results: </strong>The mean age of the participants at baseline was 67.05 ± 6.30 years. Compared to non-sarcopenia adults, those with possible sarcopenia and sarcopenia had a 39% (HR = 0.61, 95%CI: 0.52-0.71) and 45% (HR = 0.55, 95%CI: 0.45-0.67) lower likelihood of successful aging, respectively, with a significant dose-response relationship (P < 0.001). Sleep durations of 6-8 h, 8-9 h and ≥ 9 h increased the likelihood of successful aging by 49% (HR = 1.49, 95% CI: 1.25-1.77), 46% (HR = 1.46, 95% CI: 1.19-1.78) and 48% (HR = 1.48, 95% CI: 1.21-1.91), respectively, compared to < 6 h sleep. Joint analysis revealed that individuals with sarcopenia and short sleep (< 6 h) had the lowest probability of successful aging (HR = 0.38, 95% CI: 0.28-0.52), suggesting a cumulative detrimental effect. Both possible sarcopenia and sarcopenia was associated with decreased likelihood of no major disease, no disability, high cognitive function, and no depressive symptoms in the successful aging. Subgroup analyses showed consistent effects of sarcopenia across demographic groups. Sensitivity analyses confirmed the robustness and reliability of the primary findings.</p><p><strong>Conclusions: </strong>Sarcopenia and short sleep duration independently and jointly hinder successful aging. Community sarcopenia screening integrated into primary care and advocating adequate sleep duration may served as a cost-effective successful aging strategy.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"679"},"PeriodicalIF":3.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12406554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of aquatic therapy combined with transcranial direct current stimulation (tDCS) on proprioception and gait speed in older adults with knee osteoarthritis: an eight-week randomized sham-controlled trial.","authors":"Zahra Bagherpoor Kalkhoran, Razieh Khanmohammadi","doi":"10.1186/s12877-025-06253-5","DOIUrl":"10.1186/s12877-025-06253-5","url":null,"abstract":"<p><strong>Background: </strong>Knee osteoarthritis (KOA) is a prevalent condition among older adults, leading to impaired proprioception and reduced gait speed, which compromise mobility and quality of life. While aquatic therapy and transcranial direct current stimulation (tDCS) have individually shown potential for enhancing motor and sensory functions, their combined effects are not well understood.</p><p><strong>Objective: </strong>This study aimed to evaluate the combined effects of aquatic therapy and tDCS on knee proprioception and gait speed in older women with KOA.</p><p><strong>Methods: </strong>A randomized, triple-blind, parallel-group, sham-controlled clinical trial was conducted with 68 elderly women with KOA (aged 63-68 years). Participants were allocated into four groups: (1) Aquatic Therapy + Sham tDCS (2), Aquatic Therapy + Real tDCS (3), Real tDCS, and (4) Sham tDCS. Interventions were conducted twice weekly over an 8-week period. Knee proprioception was assessed using a digital goniometer, and gait speed was measured via the 10-Meter Walk Test under normal and dual-task conditions. Data were analyzed using analysis of covariance (ANCOVA), controlling for height and baseline scores.</p><p><strong>Results: </strong>Paired t-tests revealed significant improvements in gait speed (under both normal and dual-task conditions) and knee proprioception in all intervention groups, except the Sham tDCS group (p ≤ 0.05). Analysis of covariance (ANCOVA), controlling for height and pre-test scores, showed significant between-group differences in both gait speed and knee proprioception. Post hoc comparisons indicated that the Aquatic Therapy + Real tDCS group exhibited significantly greater improvements in knee proprioception compared to both the Aquatic Therapy + Sham tDCS and Real tDCS groups (p ≤ 0.05), supporting the additive effect of real tDCS on sensory outcomes. However, no significant differences in gait speed were observed between the Aquatic Therapy + Real tDCS and Aquatic Therapy + Sham tDCS groups under either normal or dual-task conditions.</p><p><strong>Conclusion: </strong>The combined use of aquatic therapy and tDCS appears to enhance proprioceptive function more effectively than either intervention alone, while improvements in gait speed seem primarily driven by aquatic therapy. These findings suggest that tDCS may offer sensory-specific benefits in multimodal rehabilitation for older adults with KOA. Further research is warranted to assess the long-term effects, evaluate outcomes under varied task demands, and examine the generalizability to broader populations.</p><p><strong>Trial registration: </strong>This clinical trial was registered with Iran's Clinical Trial Registration Center (IRCT)[IRCT20190908044722N8] on 8 January 2025.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"676"},"PeriodicalIF":3.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12403502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Excessive reassurance-seeking and anxiety among Chinese new urban older adults: the role of attention to negative information and resilience.","authors":"Yang Sun, Cornelia Wrzus, Shaobo Lv","doi":"10.1186/s12877-025-06382-x","DOIUrl":"10.1186/s12877-025-06382-x","url":null,"abstract":"<p><strong>Background: </strong>Policy-driven relocation of older adults from rural to urban areas in China is a significant stressor that often exacerbates anxiety. The mechanisms through which excessive reassurance seeking (ERS) heightens anxiety in this population remain poorly understood.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted with 301 relocated older adults (aged 60-89 years; 52.5% women) in Jilin Province. Participants completed validated self-report measures assessing ERS, attention to negative information (ANI), resilience, and anxiety. Pearson correlations were used to assess bivariate relationships among the main variables. The PROCESS macro was employed to examine (a) the mediating role of ANI on the association between ERS and anxiety; (b) the moderating influence of resilience on the ERS-to-ANI path, thereby constituting a moderated-mediation model; and (c) the full-path robustness check of the model.</p><p><strong>Results: </strong>Participants reported clinically meaningful levels of anxiety, which were positively associated with excessive reassurance seeking. The association between ERS and anxiety was mediated primarily through ANI. Further analysis found that the indirect effect of ERS on anxiety through ANI was more pronounced in the presence of higher levels of resilience.</p><p><strong>Conclusion: </strong>ERS exacerbates anxiety mainly by amplifying negative attention bias. Even highly resilient individuals may experience more severe anxiety if they exhibit this attention bias. These findings emphasize that interventions should not only focus on fostering resilience, but also incorporate training to mitigate negative attention biases.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"680"},"PeriodicalIF":3.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12406410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of resistance training for older adults with cognitive frailty: a randomized controlled trial.","authors":"TingTing Wu, XiaoXia Wang, Yifei Xu, Chufan Zhang, MeiZhen Huang, Hong Li","doi":"10.1186/s12877-025-06311-y","DOIUrl":"10.1186/s12877-025-06311-y","url":null,"abstract":"<p><strong>Background: </strong>Cognitive decline and the progression to dementia are hastened in individuals with cognitive frailty. Exercise interventions benefit cognitive function in patients with Mild Cognitive Impairment (MCI) or frailty. While the optimal implementation of resistance training for cognitive frailty is still being explored. The aims of this study were to develop and evaluate the effect of a novel, hybrid online-offline resistance training regimen for the cognitive frailty cohort.</p><p><strong>Methods: </strong>In this single-blind, randomized controlled trial, 68 individuals with MCI and frailty or pre-frailty were enrolled and allocated to either a resistance training program or a standard senior fitness exercise regimen. The resistance training, designed based on the intervention mapping framework, comprised a 12-week hybrid intervention, blending online and offline sessions, conducted three times a week. The primary outcomes measured were global cognitive function and physical function. Data analysis was conducted meticulously using covariance analysis, with a commitment to the intention-to-treat principle.</p><p><strong>Results: </strong>The hybrid online-offline resistance training regimen was both safe and feasible. Participants in the resistance training group exhibited significantly greater improvements in global cognitive function as measured by MoCA (F = 6.289, p = 0.011) and 4-meter walk time (F = 10.951, P = 0.002), with least squares mean difference of 1.299 (95% CI: 0.306 to 2.291) and - 0.576 (95% CI: -0.924 to -0.228), and with effect size of 0.095, 1.114, respectively. Furthermore, resistance training proved more effective in boosting attention and enhancing quality of life. Between the groups, no significant differences were noted in executive, language, and memory functions, as well as in measures of anxiety, depression, and self-efficacy, among other aspects.</p><p><strong>Conclusions: </strong>Our study demonstrated that a hybrid online-offline resistance training model is safe and effective for older people with cognitive frailty, providing modest benefits over traditional exercises in enhancing global cognitive function, attention, physical function, and quality of life.</p><p><strong>Trial registration: </strong>ChiCTR2100043826 was registered on 4 March 2021.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"681"},"PeriodicalIF":3.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12406349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The mediating effect of social networks and depressive symptoms on the relationship between older adults' participation in volunteer activities and life satisfaction: a cross-sectional study involving Chinese older adults.","authors":"Yinliang Ge, Wenjun Jiang, Mo Xue, Yanxia Lyu, Lixin Hong, Kan Tian","doi":"10.1186/s12877-025-06362-1","DOIUrl":"10.1186/s12877-025-06362-1","url":null,"abstract":"<p><strong>Background: </strong>Volunteer activities have been widely acknowledged as a meaningful form of social participation for older adults, contributing to their subjective well-being. However, the psychological and interpersonal mechanisms linking volunteering to life satisfaction remain insufficiently explored. In particular, how social networks and depressive symptoms jointly mediate this relationship in the Chinese context is yet to be clarified.</p><p><strong>Purpose: </strong>This study investigates the association between older adults' participation in volunteer activities and their life satisfaction, with a focus on the sequential mediating roles of social networks and depressive symptoms.</p><p><strong>Methods: </strong>Data were drawn from the 2020 wave of the Chinese Longitudinal Aging Social Survey (CLASS), involving 9,828 respondents aged 60 and older. Volunteer participation was measured through self-reported engagement in community service activities. Social networks were assessed using the six-item Lubben Social Network Scale (LSNS-6), while depressive symptoms were evaluated by the 10-item Center for Epidemiologic Studies Depression Scale (CES-D). Life satisfaction was measured with a single-item indicator. A serial mediation model was tested using structural equation modeling with bootstrapping procedures (5,000 samples) to estimate indirect effects.</p><p><strong>Results: </strong>Participation in volunteer activities was positively associated with life satisfaction among older adults. The relationship was partially mediated by social networks and depressive symptoms in sequence. Specifically, volunteering predicted stronger social networks (a₁ = 0.121, p < .001), which in turn were associated with lower depressive symptoms (a₃ = - 0.135, p < .001), subsequently enhancing life satisfaction (b₂ = - 0.094, p < .001). The total indirect effect through both mediators was significant (a₁ × a₃ × b₂ = 0.002, 95% CI [0.001, 0.004]). The direct effect remained significant (c' = 0.095, 95% CI [0.060, 0.130]), indicating a partial mediation pattern.</p><p><strong>Conclusion: </strong>This study reveals that social networks and depressive symptoms jointly mediate the relationship between volunteer participation and life satisfaction among older adults in China. These findings provide empirical support for integrating social and psychological mechanisms into models of active ageing. Promoting volunteer engagement may enhance both social connectedness and mental health, ultimately improving quality of life in later life.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"678"},"PeriodicalIF":3.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12403472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined lifestyle habits, subjective well-being, and all-cause mortality among older adults in China.","authors":"Chunsu Zhu, Zhiwei Lian, Jing Sun, Yongying Huang, Shengmei Li, Heng Zhang, Jianmin Wang","doi":"10.1186/s12877-025-06345-2","DOIUrl":"https://doi.org/10.1186/s12877-025-06345-2","url":null,"abstract":"<p><strong>Background: </strong>Although studies have demonstrated that both lifestyles and subjective well-being (SWB) are associated with mortality risk, the joint effects of a healthy lifestyle and SWB on the risk of mortality are unclear. This study aimed to explore the combined impact of lifestyles and SWB on total mortality among the older Chinese population.</p><p><strong>Methods: </strong>Data were obtained from the Chinese Longitudinal Healthy Longevity Survey conducted from 2002 to 2018. A total of 13,282 participants aged ≥ 65 years were included. SWB was measured by an eight-item tool covering life satisfaction, optimism, conscientiousness, anxiety, loneliness, personal control, feeling useless, and happiness. A total healthy lifestyle score was calculated by summing across five lifestyle factors (smoking, drinking, exercise, dietary diversity and body mass index), ranging from 0 to 5, and was categorized into the following groups: healthy (4-5 points), intermediate (2-3 points) and unhealthy (0-1 point). Cox proportional regression analyses were carried out adjusting for demographic characteristics and other potential confounders.</p><p><strong>Results: </strong>In total, 8549 (64.4%) deaths were reported during the follow-up period. Compared with the higher healthy lifestyle score, the hazard ratios (HRs) for all-cause mortality for the intermediate and unhealthy lifestyle scores were 1.11 (1.04-1.17) and 1.17 (1.09-1.26), respectively, independent of SWB. A similar relationship between SWB and total mortality was observed, independent of lifestyle factors. The participants who had worse SWB experienced a 1.19 (1.14-1.25) higher risk of total mortality in comparison with those who had better SWB after adjusting for lifestyles. Combinations of unhealthy lifestyle scores and poor SWB were associated with an increased risk of total mortality, and the highest risk was found among participants with a healthy lifestyle score of 0-1 and worse SWB (HR = 1.41, 95% CI = 1.28-1.55).</p><p><strong>Conclusions: </strong>A stronger risk of total mortality was found when worse SWB and unhealthy lifestyle occurred together, suggesting that a comprehensive approach to healthy lifestyle and SWB might be a potential strategy to improve longevity.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"675"},"PeriodicalIF":3.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduced perioperative sensory impairment could lower postoperative delirium incidence: a before-and-after study in older patients with hip fracture.","authors":"Jan Wilhelm Busse, Alexander Ranker, Manfred Gogol, Christian Macke, Emmanouil Liodakis, Derya Strack, Lukas Hinken, Carolin Jung","doi":"10.1186/s12877-025-06318-5","DOIUrl":"https://doi.org/10.1186/s12877-025-06318-5","url":null,"abstract":"<p><strong>Background: </strong>Postoperative delirium (POD) is a common complication in older patients. Multicomponent prevention reduces POD but requires substantial resources. The effect of single interventions derived from multicomponent programs remains elusive, but it is essential to assess their effect to identify which components are meaningful. This study investigates whether a single intervention from a multicomponent program may reduce the incidence of POD.</p><p><strong>Methods: </strong>This prospective, single-center before-and-after study evaluated older surgery patients at a university hospital's geriatric trauma center between July 2020 and November 2021. Inclusion criteria were age ≥ 70 years and a proximal femoral fracture. A control cohort (CC) left their dentures, vision, and hearing aids on the ward throughout surgery, while an intervention cohort (IC) used them until anesthesia induction and received them back when they regained consciousness. Therefore, IC obtained a transport case for hygienic storage and perioperative device management. The time of sensory aid removal was measured to ensure proper implementation. Outcomes were the incidence of POD (assessed via the 3-min Diagnostic Confusion Assessment Method at admission and twice daily for three days postoperatively), patient satisfaction, and recovery (evaluated via Quality of Recovery-9), length of hospital stay, postoperative monitoring time, Barthel-index, and 30-day mortality.</p><p><strong>Results: </strong>248 patients were screened for eligibility. Following a dropout rate of n = 166, the cohorts were: CC n = 40 and IC n = 42. Both cohorts had similar baseline and treatment characteristics. The intervention significantly reduced the median time of sensory aid removal (CC 12h 14min, IC 12min, p < 0.001), and the incidence of POD overall (CC 65.0%, IC 40.5%, p = 0.026). The length of hospital stay and long-term recovery outcomes remained insignificant. However, postoperative monitoring time correlated with time of sensory aid removal (r_s = 0.518, p < 0.001, n = 62), and median quality of recovery improved on average (CC 12.75, IC 15.62, p < 0.001).</p><p><strong>Conclusion: </strong>Reduced perioperative sensory impairment may reduce the incidence of POD, decrease postoperative monitoring time, and be associated with a better postoperative recovery. Therefore, multimodal preventative efforts should include reducing sensory aid removal.</p><p><strong>Trial registration: </strong>German Clinical Trial Register (DRKS-ID DRKS00022085); 07/07/2020.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"673"},"PeriodicalIF":3.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of diabetes mellitus and chronic obstructive pulmonary disease on mortality among people with dementia: a nationwide population-based cohort study.","authors":"Anna Bebe, Tora Grauers Willadsen, Jakob Kragstrup, Anni Brit Sternhagen Nielsen, Anne Møller, Jens Søndergaard, Volkert Siersma, Dagný Rós Nicolaisdóttir, Pernille Hølmkjaer, Frans Boch Waldorff","doi":"10.1186/s12877-025-06319-4","DOIUrl":"https://doi.org/10.1186/s12877-025-06319-4","url":null,"abstract":"<p><strong>Background: </strong>People with dementia have higher mortality compared to individuals without dementia. Dementia itself and comorbidity, but also impaired function and self-care, probably all contribute to the high mortality. Dementia is characterized by a high degree of comorbidity and demand for self-care, and so are Diabetes Mellitus (DM) and Chronic Obstructive Pulmonary Disease (COPD). All three diseases can severely impact functioning and quality of life. The aim of this study is to examine the excess mortality associated with DM and COPD in patients with dementia, compared with persons without these diseases, in Danish residents aged ≥ 65 years.</p><p><strong>Methods: </strong>The cohort included all individuals aged ≥ 65 years living in Denmark on January 1st, 2009, in total 874,426 individuals. All-cause mortality among persons with dementia, DM, and COPD was compared to persons free of these diseases. We estimated the incidence rate ratio (IRR), with confidence intervals (CI), for all-cause mortality associated with the three diseases separately, and in combination, using Cox regression models. Finally, to understand the consequences when diseases coexist, an interaction effect on mortality was calculated for all combinations of diseases as the IRR for the combination divided by the product of the IRR of the individual diseases.</p><p><strong>Results: </strong>The increase in all-cause mortality was IRR 2.86 (95% CI 2.83-2.89) for dementia, 1.45 (1.44-1.47) for DM, and 2.22 (2.20-2.24) for COPD. For the disease combinations mortality was IRR 3.93 (95% CI 3.83-4.04) for dementia and DM, 5.05 (95% CI 4.92-5.19) for dementia and COPD, and 3.34 (95% CI 3.26-3.41) for DM and COPD. Mortality for the combination of all three diagnoses was 5.66 (95% CI 5.36-5.98). The interaction effect on mortality was < 1, i.e. lower than expected from the total mortality related to the individual diseases, for all possible combinations of the three diseases, and lowest when dementia was involved in the combination.</p><p><strong>Conclusion: </strong>Dementia, DM, and COPD were independently, and in combination, associated with increased mortality. Contrastingly, coexistence seemed less deadly than the diseases on their own, possibly because they being discovered at an earlier stage, still, emphasizing the importance of focusing on shared health factors when treating patients with dementia.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"672"},"PeriodicalIF":3.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study protocol for a randomised controlled trial: effect of an interdisciplinary psycho-educational intervention programme on caregivers of dependent older adults.","authors":"Sara Jiménez García-Tizón, Celia Sánchez Gómez, María Belén Bueno Martínez, Ana Belén Navarro Prados, Eduardo José Fernández Rodríguez","doi":"10.1186/s12877-025-06305-w","DOIUrl":"https://doi.org/10.1186/s12877-025-06305-w","url":null,"abstract":"<p><strong>Background: </strong>Caring for an older dependent adult with cognitive impairment can have negative consequences for the family caregiver. Interdisciplinary interventions are necessary to address their needs jointly and comprehensively. While attempts have been made to improve their situation from different disciplines in isolation, a collaborative approach is required to ensure the best possible outcome.</p><p><strong>Methods: </strong>A parallel, randomized, controlled clinical trial with two arms will be conducted at the Teaching and Clinical Unit of Occupational Therapy (UDATO) and the Municipal Unit for Psychosocial Support for Older Adults (UMAPS), both of which belong to the University of Salamanca and are in agreement with the City Council of Salamanca, Spain. The trial will also be conducted at the University Assistance Complex of Salamanca (CAUSA). Family caregivers, aged 60 years or older, of dependent older adults with cognitive impairment will be recruited. Participants will be randomly assigned to an intervention group (IG) or a control group (CG). The IG will participate in an interdisciplinary psychoeducational programme co-led by psychology and occupational therapy professionals. The programme consists of 12 weekly sessions (90 min each) over 3 months, covering topics such as emotional regulation, caregiver burden, cognitive-behavioural strategies, problem-solving, functional stimulation, and promotion of autonomy. Three monthly reinforcement sessions will follow. The CG will receive routine follow-up and resource information. Outcomes will be assessed at baseline and post-intervention using validated instruments: the Caregiver Burden Interview (CBI), the CES-D Depression Scale, the Psychosocial Support Questionnaire (PSQ), the General Health Questionnaire (GHQ), the WHOQOL-AGE and the Bayer-ADL Scale.</p><p><strong>Discussion: </strong>This study aims to enhance conventional clinical practice for family caregivers of dependent older adults. This will be achieved through an interdisciplinary psychoeducational intervention that aims to reduce overload and depressive symptomatology, increase social support, improve health and perceived quality of life, and enhance understanding of the syndrome. The intervention will also focus on managing difficult situations associated with day-to-day caregiving, managing emotions and associated erroneous beliefs, and promoting self-care. Additionally, the study aims to improve the functionality of the cared-for person.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov Identifier: NCT06326151. Registration date: March 22, 2024.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"674"},"PeriodicalIF":3.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Caribbean American Dementia and Aging Study: protocol for a population-based study of older adult health and dementia in Cuba, the Dominican Republic, and Puerto Rico.","authors":"Mao-Mei Liu, Jorge Llibre-Guerra, Chris Soria, Jing Li, Tania Zayas Llerena, Guillermina Rodriguez, Daisy Acosta, Ivonne Jiménez Velázquez, Juan J Llibre-Rodriguez, William H Dow","doi":"10.1186/s12877-025-06131-0","DOIUrl":"https://doi.org/10.1186/s12877-025-06131-0","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"669"},"PeriodicalIF":3.8,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12395809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}