BMC Geriatrics最新文献

{"title":"The effect of sensory manipulation on the static balance control and prefrontal cortex activation in older adults with mild cognitive impairment: a functional near-infrared spectroscopy (fNIRS) study.","authors":"Guocai Xu, Mian Zhou, Jiangna Wang, Dewei Mao, Wei Sun","doi":"10.1186/s12877-024-05624-8","DOIUrl":"10.1186/s12877-024-05624-8","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the modulatory role of prefrontal cortex (PFC) activity in older adults with mild cognitive impairment (MCI) when sensory cues were removed or presented inaccurately (i.e., increased sensory complexity) during sensory manipulation of a balance task. The research sheds light on the neural regulatory mechanisms of the brain related to balance control in individuals with MCI.</p><p><strong>Methods: </strong>21 older adults with MCI (male/female: 9/12, age: 71.19 ± 3.36 years) were recruited as the experimental group and 19 healthy older adults (male/female: 10/9, age: 70.16 ± 4.54 years) as the control group. Participants were required to perform balance tests under four standing conditions: standing on a solid surface with eyes open, standing on a foam surface with eyes open, standing on a solid surface with eyes closed, and standing on a foam surface with eyes closed. Functional Near-Infrared Spectroscopy (fNIRS) and force measuring platform are used to collect hemodynamic signals of the PFC and center of pressure (COP) data during the balance task, respectively.</p><p><strong>Results: </strong>Under the eyes open condition, significant Group*Surface interaction effects were found in the mean velocity of the COP (MVELO), the mean velocity in the medial-lateral (ML) direction (MVELO_ml) and the 95% confidence ellipse area of the COP (95%AREA-CE). Additionally, significant Group*Surface interaction effect was found in the left orbitofrontal cortex (L-OFC). The significant group effects were detected for three ROI regions, namely the left ventrolateral prefrontal cortex (L-VLPFC), the left dorsolateral prefrontal cortex (L-DLPFC), the right dorsolateral prefrontal cortex (R-DLPFC). Under the eyes closed condition, the significant Group*Surface interaction effects were found in root mean square (RMS), the RMS in the ML direction (RMS_ml) and the 95%AREA-CE. Additionally, significant group effects were detected for five ROI regions, namely R-VLPFC, the left frontopolar cortex (L-FPC), L-DLPFC, R-DLPFC and R-OFC.</p><p><strong>Conclusion: </strong>Our study emphasizes the role of the PFC in maintaining standing balance control among older adults with MCI, particularly during complex sensory conditions, and provides direct evidence for the role of the PFC during balance control of a clinically relevant measure of balance.</p><p><strong>Trial registration: </strong>ChiCTR2100044221, 12/03/2021.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"24 1","pages":"1020"},"PeriodicalIF":3.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11660590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age- and sex-disaggregated disease burden among the older persons in India.","authors":"G Anil Kumar, Anamika Pandey, Sailesh Mohan, Dorairaj Prabhakaran, Rakhi Dandona","doi":"10.1186/s12877-024-05614-w","DOIUrl":"10.1186/s12877-024-05614-w","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;In the context of the increasing number and proportion of population aged 60 years or more in India, it is imperative to understand their health needs for ensuring healthy ageing.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we identified the top ten causes of disability-adjusted life years (DALYs), years of life lost (YLLs), and years lived with disability (YLDs) disaggregated by sex and age groups (60-64 years, 65-69 years, 70-74 years, 75-79 years, and ≥ 80 years) for India in 2019. We analysed the proportional contribution of individual causes to the total DALYs due to communicable diseases (CMNNDs), non-communicable diseases (NCDs), and injuries disaggregated by age and sex. We report the state-level heterogeneity in the crude DALY rate for CMNNDs, NCDs, and injuries for older persons disaggregated by sex. Additionally, we reviewed if the data capture of service delivery indicators on older persons were age- and sex-disaggregated in the Health and Wellness Centres (HWCs), and in the National Programs aimed at the Health Care for the Elderly (NPHCE), Prevention and Control of Non-communicable Diseases (NP-NCD), Control of Blindness and Visual Impairment (NPCBVI), Prevention & Control of Deafness (NPPCD), the Mental Health Program (NMPH), and the AYUSH Musculoskeletal Disorders Program (MSDP) within the context of disease burden.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The older persons accounted for a total of 136.1 million DALYs (29.1% of the total DALYs) in 2019 of which 77.9% were from NCDs, 14.8% from CMNNDs, and 7.3% from injuries, and nearly two-thirds of DALYs were accounted by YLLs. In NCDs, cardiovascular diseases, chronic respiratory diseases, neoplasms, diabetes and kidney diseases, and musculoskeletal disorders accounted for nearly 80% of DALYs for both sexes. There were variations in the magnitude of disease burden by specific diseases and conditions between females and males, and by age groups within both sexes particularly for injuries and CMNNDs. Injuries accounted for more YLDs than YLLs, ranging between 5.9%-15.2% for females and 15.3%-17.3% for males, with the females having a higher contribution to total injury related DALYs due to falls as compared to the males (54.4% vs 36.6%), whereas the males had a higher contribution to total DALYs due to road injuries (33.8% vs 19.4%). There was substantial variation in the crude DALY rates of major disease groups by the two sexes across the states of India in 2019. The crude DALY rate for CMNNDs varied between 3.6 times -3.7 times between the states for females and males, respectively; NCDs varied between 1.3 times -1.9 times, and injuries varied 2.0 times -1.7 times. The capture of service utilisation indicators was not age- or sex-disaggregated in NPHCE, NPCBVI, NMHP, MSDP, and HWCs; sex-disaggregation was available in NP-NCD but not age-disaggregation; sex-disaggregated data wa","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"24 1","pages":"1019"},"PeriodicalIF":3.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11661056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of a self-administered frailty screening questionnaire for the effectiveness of functional rehabilitation evaluated with the locomotor functional independence measure in a geriatric rehabilitation unit: a multicentre cohort study.","authors":"Jan Chrusciel, Ramatoulaye Ndoye, Biné-Mariam Ndiongue, Marie-Anne Fournier, Fariba Kabirian, Manon Pondjikli, Valentine Dutheillet-de-Lamothe, Gilles Berrut, Yves Rolland, Stéphane Sanchez","doi":"10.1186/s12877-024-05605-x","DOIUrl":"10.1186/s12877-024-05605-x","url":null,"abstract":"<p><strong>Background: </strong>Patient Reported Outcome Measures (PROMs) are questionnaires that collect health data directly from the patient, without any intervention from a third party. The aim of rehabilitation units is to restore function. Functional gain can be evaluated with classic scales, such as the locomotor subscale of the Functional Independence Measure. This study aimed to assess the accuracy of a new self-assessment questionnaire pertaining to physical, sensory and cognitive ability (abbreviated SEPCO) for the prediction of functional prognosis in older patients admitted to a rehabilitation unit.</p><p><strong>Methods: </strong>In this multicentre observational study including patients admitted to 12 rehabilitation centres in France, all included patients completed the SEPCO on admission. Poor response to rehabilitation was defined as relative effectiveness < 40% on the evolution of the locomotor FIM subscale. Components of the questionnaire potentially associated with the outcome of rehabilitation were confirmed for inclusion upon expert review and summed to form an overall score. The final score had five components: the depression score of the HADS, the SOFRESC vision score, the SOFRESC balance score, the stress urinary incontinence subscale of the USP, and the EPICES socio-economic deprivation score. A logistic regression model adjusted for baseline characteristics assessed the performance of the SEPCO score to predict change in functional status, defined by the relative functional gain for the locomotion subscale of the Functional Independence Measure (FIM).</p><p><strong>Results: </strong>A total of 153 patients (mean age 79.2 ± 8.1 years, 72.5% women) were included. By multivariate analysis, a 5-scale SEPCO score ≥ 1.1 predicted worse functional improvement with an odds ratio (OR) of 2.575, 95% Confidence Interval (CI) 1.081 to 6.133, p = 0.03. Sensitivity for this threshold was 67.4% (95% CI 52.0-80.5%), with a specificity of 58.8% (95% CI 46.2-70.6%). Having a SEPCO ≥ 1.1 almost doubled the probability of poor response to rehabilitation (from 27.3 to 52.5%).</p><p><strong>Conclusion: </strong>The SEPCO score can predict poor functional gain from rehabilitation. Future studies should validate this score on an external cohort. The SEPCO could serve as a complement to the initial clinical evaluation performed by physicians, and assist physicians in setting each patient's rehabilitation goals.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"24 1","pages":"1013"},"PeriodicalIF":3.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11656562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between post-lunch napping duration and social participation among the Chinese older adults: a cross-sectional study.","authors":"Xiaozhen Fu, Rong Lin, Yuanjiao Yan, Chenshan Huang, Bingjie Wei, Hong Li","doi":"10.1186/s12877-024-05593-y","DOIUrl":"10.1186/s12877-024-05593-y","url":null,"abstract":"<p><strong>Background: </strong>Social participation (SP) affects the physical and mental health of older adults. Post-lunch napping is a prevalent lifestyle practice observed among older adults, and it may have an impact on their SP. However, research that explores the association between these factors is limited, and we thus aimed to examine this association.</p><p><strong>Methods: </strong>We conducted a cross-sectional study using data from the China Health and Retirement Longitudinal Study (CHARLS), focusing on participants aged 60 and older. SP was measured by both the number and frequency of activities based on participant self-reports. The duration of post-lunch napping was also self-reported. We explored the association between post-lunch napping duration and SP using logistic regression, subgroup analysis, and Restrictive Cubic Spline (RCS) analysis.</p><p><strong>Results: </strong>We included 4259 participants in the study. Post-lunch napping demonstrated a significant association with decreased odds ratio of poor SP in fully adjusted logistic regression models (odds ratio = 0.77, 95% CI: 0.66 ~ 0.90, p = 0.011). Subgroup analysis indicated consistent proportional effects across all subgroups (p > 0.05). RCS analysis revealed a non-linear \"J\"-shaped relationship between post-lunch napping duration and SP, with the lowest odds ratio corresponding to a duration of 34.37 min.</p><p><strong>Conclusion: </strong>Our study suggests that a moderate duration of post-lunch napping, ideally around 34 min, might have the potential to enhance SP, whereas exceeding this duration could could potentially have a limiting effect. This observation implies that incorporating moderate post-lunch napping into health management strategies for older adults might offer some advantages.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"24 1","pages":"1005"},"PeriodicalIF":3.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11658246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of an inspiratory muscle fatigue protocol on older adults on respiratory muscle strength, muscle oxygen saturation, and functional capacity: a randomized controlled trial.","authors":"Arturo Ladriñán-Maestro, Jorge Sánchez-Infante, Daniel Martín-Vera, Alberto Sánchez-Sierra","doi":"10.1186/s12877-024-05610-0","DOIUrl":"10.1186/s12877-024-05610-0","url":null,"abstract":"<p><strong>Background: </strong>The fatigue of the inspiratory musculature, particularly the diaphragm, has been demonstrated to exert systemic effects on the body, impacting cardiovascular and performance outcomes. This study aimed to evaluate the influence of an inspiratory muscle fatigue protocol on respiratory muscle strength, functionality, and muscle oxygen saturation in older adults.</p><p><strong>Methods: </strong>A single-blinded randomized controlled clinical trial was conducted on twenty-four older adults aged over 60 years, who met inclusion criteria were physically independent in terms of gait and functionality. Participants were randomly assigned to one of three groups: control group, inspiratory muscle fatigue group, or activation group. Diaphragmatic ultrasonography (diaphragmatic thickness, thickening fraction, diaphragm movement curve), maximal inspiratory mouth pressure, muscle oxygen saturation, and functionality (timed up and go test, for five times sit to stand test) were used to measure the study variables at two time points: pre-intervention (T1) and post-intervention (T2).</p><p><strong>Results: </strong>In the maximum inspiratory pressure variable in the activation group an increase was found between baseline and post-treatment of 3.00 ± 0.93 cmH2O (P < 0.01), while in the inspiratory muscle fatigue a decrease of -6.75 ± 2.66 cmH2O (P < 0.01) was found. In addition, the inspiratory muscle fatigue group showed lower scores for respiratory and functional variables after performing the diaphragmatic fatigue intervention than the activation and control group (P < 0.05), on the other hand, the activation group showed more positive values for functional and respiratory capacity variables after performing the inspiratory muscle activation training (P < 0.05).</p><p><strong>Conclusions: </strong>Fatigue of the inspiratory musculature appears to negatively impact inspiratory muscle strength, peripheral muscle strength, muscular oxygenation, and functionality in older adults. Activation of the inspiratory musculature could contribute to improved respiratory muscle strength and function in these individuals.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov ID: NCT06266013.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"24 1","pages":"1015"},"PeriodicalIF":3.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11657661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social patterning of cognitive impairment in Colombia: evidence from the SABE 2015 study.","authors":"Alejandra Guerrero Barragán, Inés Elvira Gómez, Diego Iván Lucumí Cuesta","doi":"10.1186/s12877-024-05432-0","DOIUrl":"10.1186/s12877-024-05432-0","url":null,"abstract":"<p><strong>Introduction: </strong>Dementia, an increasingly critical public health concern in low and middle-income countries, is associated with lower socioeconomic status, early cognitive impairment, and elevated dementia-related mortality risk. This study seeks to estimate the prevalence of cognitive impairment, investigate its links with social indicators, and visualize social gradients across different regions in Colombia.</p><p><strong>Methods: </strong>Secondary data analysis from the SABE 2015 survey, multinomial regression analyses, and equiplot graphs.</p><p><strong>Results: </strong>A sample of 23,694 individuals 60 years or older from Colombia. Higher risks were observed among individuals with dark skin color (OR 1.27; 95%CI: 1.10 - 1.47), lower educational levels (OR 3.01; 95%CI:2.04 - 4.42) and reading illiteracy (OR 2.14; 95%CI: 1.87 - 2.46). Inequity patterns were identified by region of residence and income.</p><p><strong>Discussion: </strong>This study underscores the need for targeted interventions aimed at reducing health inequities. The results highlight the higher prevalence rates of cognitive impairment among socially disadvantaged individuals.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"24 1","pages":"1002"},"PeriodicalIF":3.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11658237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypertension may lead to cognitive dysfunction in older adults via methylmalonic acid: evidence from NHANES 2011-2014 population.","authors":"Ying Xu, Rucheng Chen, Paulus Torkki, Weijun Zheng, An Chen","doi":"10.1186/s12877-024-05599-6","DOIUrl":"10.1186/s12877-024-05599-6","url":null,"abstract":"<p><strong>Background: </strong>An enriched understanding is necessary concerning the association between hypertension and cognitive impairment in older adults, particularly regarding the potential underlying mechanisms at a biological level. This study aimed to explore the mediating role of methylmalonic acid (MMA) in the hypertension-cognition link in the older population.</p><p><strong>Methods: </strong>A total of 2762 adults (age > = 60 years) from the National Health and Nutrition Examination Survey (NHANES) 2011-2014 participated. Cognitive function was assessed using a combination of the Animal Fluency Test (AFT), the Digit Symbol Substitution Test (DSST), and the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) Word List Learning Test. Self-reported hypertension diagnosis, antihypertensive medications use, and blood pressure examinations were used to identify hypertension. Serum MMA (sMMA) levels were collected. Weighted multiple linear regressions and mediation analysis were applied. A subgroup analysis by sex and age was performed.</p><p><strong>Results: </strong>After adjusting for potential confounding factors, we observed a significant mediating effect of the sMMA level in the hypertension-cognition link, accounting for 11.14% (95% CI 4.09%-14.00%, p < 0.001) of the relationship in older adults. The proportion mediated by the sMMA level in the relationship between hypertension and cognitive function was higher in males (15.23%, 95%CI 1.32%-27.00%, p < 0.001) than in females (6.61%, 95%CI 2.12%-10.00%, p < 0.001). This mediating effect of sMMA was observed only in individuals aged 68 years and older (11.31%, 95%CI 3.80%-16.00%, p < 0.001), with no significant mediation detected in those younger than 68 years.</p><p><strong>Conclusion: </strong>Hypertension may lead to cognitive dysfunction in older adults through MMA. Apart from its role as a biomarker reflecting vitamin B12, MMA may act as an independent neurotoxin capable of inducing brain injury and cognitive impairment. Addressing MMA accumulation, such as through Vitamin B12 supplementation, may have a potential to mitigate hypertension-induced cognitive decline in older adults. Special attention could be paid to hypertensive males with an advanced age (> = 68) to address MMA-related cognitive decline.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"24 1","pages":"1009"},"PeriodicalIF":3.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11656983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of surgical efficacy between direct anterior approach and posterolateral approach in the treatment of sarcopenia with femoral neck fractures.","authors":"Zhaoyang Yin, Qin Hu, Bin Zhang, Jin Yi, Hailong Zhang, Jian Yin","doi":"10.1186/s12877-024-05621-x","DOIUrl":"10.1186/s12877-024-05621-x","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Femoral neck fracture (FNF) is a prevalent injury among the elderly, associated with significant morbidity and mortality. Total joint arthroplasty (TJA) has markedly enhanced the quality of life for many patients; however, the benefits of the direct anterior approach (DAA), which has gained popularity in recent years, remain a subject of debate. Sarcopenia frequently occurs in patients with FNF and is linked to adverse surgical outcomes. This study aims to compare the effects of the DAA and the posterolateral approach (PLA) on the efficacy of TJA surgery in patients with FNF who also present with sarcopenia.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This study retrospectively analyzed the clinical data of patients with FNF who underwent total hip arthroplasty (THA) using either DAA or PLA from December 2019 to December 2022. A total of 141 individuals were included, comprising 52 in the DAA group and 89 in the PLA group. The cross-sectional area (cm²) of the musculature at the pedicle level of the 12th thoracic vertebra (T12) was measured using chest computed tomography (CT). The skeletal muscle index (SMI) was calculated by dividing the cross-sectional area of the muscle at the T12 pedicle level by the square of the individual's height. Sarcopenia was diagnosed when both grip strength and SMI values fell below the diagnostic cutoff. The study compared various factors, including age, gender, SMI, body mass index (BMI), American Society of Anesthesiologists (ASA) classification, operation time, incision length, blood loss, blood transfusion, hemoglobin drop, albumin drop, postoperative time to ambulation, length of hospitalization, visual analogue scale (VAS) score, Harris score at one and six months post-surgery, complications, revision rate, one-year survival rate following surgery, and patient satisfaction.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;There were no statistically significant differences between the two groups regarding gender, age, SMI, BMI, ASA, operation time, blood transfusion, VAS score six months post-surgery, revision rate, satisfaction, and survival rate (P &gt; 0.05). The incision length, blood loss, hemoglobin drop, albumin drop, hospitalization duration, VAS score, and complication rate one month after the operation in the DAA group were all significantly lower than those in the PLA group (P &lt; 0.001). Additionally, the Harris scores at one month and six days post-operation were superior in the DAA group compared to the PLA group (P &lt; 0.001). Furthermore, the incidence of complications in the DAA group was lower than that in the PLA group (P = 0.041). Univariate and multivariate Cox regression analyses indicated that age was an independent risk factor for patients' mortality risk (95% CI: 1.064-1.479, P = 0.007).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;DAA results in reduced surgical trauma, alleviates postoperative pain, decreases the incidence of complications, enhances the recovery of patients' mobility functions, s","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"24 1","pages":"1021"},"PeriodicalIF":3.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11660708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acquisition of musical skills and abilities in older adults-results of 12 months of music training.","authors":"Hannah Losch, Eckart Altenmüller, Damien Marie, Edoardo Passarotto, Clara R Kretschmer, Daniel S Scholz, Matthias Kliegel, Tillmann H C Krüger, Christopher Sinke, Kristin Jünemann, Clara E James, Florian Worschech","doi":"10.1186/s12877-024-05600-2","DOIUrl":"10.1186/s12877-024-05600-2","url":null,"abstract":"<p><strong>Background: </strong>Older adults can acquire new skills across different domains. Practicing a musical instrument has been identified as a promising activity for improving cognition, promoting well-being, and inducing brain plasticity in older individuals. However, the mechanisms of these changes are still poorly understood. This study aims to assess musical skill acquisition in musically naïve older adults over one year of practice, focusing on individual factors influencing this process and the relations between musical skills.</p><p><strong>Methods: </strong>One hundred fifty-six healthy older adults (age = 69.5 years ± 3.2) from Hannover and Geneva with no prior musical training participated in weekly piano practice (PP) or 'music culture' (MC) sessions over a one-year period. Baseline assessments included the Cognitive Reserve Index questionnaire (CRIq) and Cognitive Telephone Screening Instrument (CogTel). Musical abilities were measured using piano performance ratings (PP group), music quizzes (MC group), and aptitude tests such as the Beat Alignment Test (BAT), Melodic Discrimination Test (MDT) and Midi Scale Analysis (MSA) at baseline and six-, twelve and 18-month timepoints. The interrelationship between musical abilities was investigated through correlational analyses, and changes impacted through individual characteristics were modeled using Bayesian statistics.</p><p><strong>Results: </strong>The PP group demonstrated moderate improvements in piano articulation and dynamics, while the MC group achieved higher scores in the music quiz. Modest improvements in MDT and MSA were observed in both groups, with the PP group showing greater progress is MSA. Higher global cognitive functioning and musical sophistication was associated with greater performance in MDT for both groups. We did not identify any links between individual characteristics, like age, CogTel, CRIq, and musical sophistication, and improvement in musical aptitude tests. Changes in different musical aptitude test scores were not correlated, and neither the development of piano skills nor the music quiz correlated with initial performances on the musical aptitude tests.</p><p><strong>Conclusion: </strong>Musically naïve older adults can acquire diverse musical abilities, which progress independently, suggesting a broad spectrum of musical abilities rather than a single general musical aptitude. Future research should also explore genetic and psychosocial factors influencing musical development.</p><p><strong>Trial registration: </strong>The Ethikkomission of the Leibniz Universität Hannover approved the protocol on 14.08.17 (no. 3604-2017), the neuroimaging part and blood sampling was approved by the Hannover Medical School on 07.03.18. The full protocol was approved by the Commission cantonale d'éthique de la recherche de Genève (no. 2016-02224) on 27.02.18 and registered at clinicaltrials.gov on 17.09.18 (NCT03674931, no. 81185).</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"24 1","pages":"1018"},"PeriodicalIF":3.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11658158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding frailty: a qualitative study of older heart failure patients' frail experience and perceptions of healthcare professionals with frailty.","authors":"Si Liu, Xiao-Yun Xiong, Ting Guo, Qin Xiang, Mei-Jun Zhang, Xing-Lan Sun","doi":"10.1186/s12877-024-05602-0","DOIUrl":"10.1186/s12877-024-05602-0","url":null,"abstract":"<p><strong>Background: </strong>Although frailty is highly prevalent in hospitalized older heart failure (HF) patients, its management is often delayed. Understanding the unique experiences of frail elderly HF patients and the perceptions of healthcare professionals (HPs) regarding frailty can facilitate the integration of frailty prevention and intervention into clinical practice. This study aimed to use a descriptive qualitative approach to obtain the experiences of frailty in older HF patients and the perceptions of HPs concerning frailty.</p><p><strong>Methods: </strong>Qualitative interviews were conducted with 16 frail elderly HF patients and 13 healthcare providers. Data were analyzed using thematic analysis.</p><p><strong>Results: </strong>The interviews yielded several themes with associated subthemes: \"a state of predicament,\" \"hope is gone and social isolation,\" \"daily adjustment and attempts to do something,\" \"thoughts on factors contributing to frailty,\" \"the need for transformation of stakeholders' mindset regarding frailty,\" \"management is imperative, but there is still a way to go\".</p><p><strong>Conclusions: </strong>Both elderly patients with HF and HPs described frailty as a state of predicament, involving being caught in life difficulties and falling into a treatment dilemma. Due to the overlap of symptoms and evaluating indicators between frailty and HF, it's essential to thoroughly understand modifiable risk factors that could worsen frailty and develop a specific frailty assessment tool for HF patients. Adequate social support, multidisciplinary collaboration, and a frailty education program for patients, caregivers, and HPs are essential to facilitate frailty management and improvement.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"24 1","pages":"1012"},"PeriodicalIF":3.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11658500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}