BMJ Open Quality最新文献

{"title":"Electronic pharmaceutical record for best possible medication history at preoperative evaluation to prevent postoperative adverse events: a quasi-experimental study.","authors":"Claire Chapuis, Jean-Luc Bosson, Jean-Didier Bardet, Marion Lepelley, Dimitri Sourd, Matthieu Roustit, Benoit Allenet, Sébastien Chanoine, Pierre Albaladejo, Pierrick Bedouch","doi":"10.1136/bmjoq-2024-003022","DOIUrl":"10.1136/bmjoq-2024-003022","url":null,"abstract":"<p><strong>Background: </strong>Access to reliable data about patient's medications before surgery represents a challenge for reducing the risk of postoperative adverse events (AE) potentially related to preoperative treatment.</p><p><strong>Objective: </strong>To evaluate the impact on AE of a nationwide ambulatory electronic pharmaceutical record (EPR) used by a pharmacist for best possible medication history (BPMH), associated with the preoperative evaluation.</p><p><strong>Methods: </strong>This quasi-experimental comparative interventional study included 750 adult patients with an available EPR, admitted to the preoperative clinic for elective orthopaedic surgery, between April 2014 and April 2017. Data analysis was completed in September 2022. In the intervention group, a pharmacist performed the BPMH using the EPR, before the patient's medical evaluation. In the control group, there was conventional preoperative evaluation. The primary outcome was the number of patients with at least one AE collected by using the trigger tool method, within 30 days after surgery. Secondary outcomes were the number of medications reported in the medical record and the number of patients with at least one documented adverse drug event (ADE) by an independent committee within 30 days after surgery.</p><p><strong>Results: </strong>Of 1924 patients admitted to the preoperative clinic, 750 patients who had a record (39%) were included (153 (41%) men; median age 61 (49-71 and 50-70) years in both groups), 375 in each group. There was a 29% reduction in the proportion of patients with at least one AE in the intervention group (110/374 patients (29%) with 165 AE vs 156/372 patients (42%) with 233 AE) (OR 0.58 (0.43-0.78), p<0.01). There were significantly more drugs reported on the medical record in the intervention group (3 (1-5) vs 2 (1-4), p<0.01). There was no significant difference between the two groups in the number of patients with ADE (71/374 patients (19%) with 96 ADE vs 80/372 patients (22%) with 108 ADE, p=0.44).</p><p><strong>Conclusions and relevance: </strong>A BPMH performed by a pharmacist using a nationwide EPR at the time of preoperative evaluation contributed to reducing AE, potentially preventing harm to patients.</p><p><strong>Trial registration number: </strong>NCT02071472.</p>","PeriodicalId":9052,"journal":{"name":"BMJ Open Quality","volume":"14 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuity of care in a pandemic: an observational study in GP-centred healthcare in Germany.","authors":"Gunter Laux, Michel Wensing, Attila Altiner, Ruediger Leutgeb","doi":"10.1136/bmjoq-2024-002944","DOIUrl":"10.1136/bmjoq-2024-002944","url":null,"abstract":"<p><strong>Background: </strong>Continuity of care (COC) refers to the sustained quality of healthcare over time and is a central element of effective general practice. High levels of COC have been associated with improved health outcomes, including reduced risks of hospitalisation. Previous research demonstrated that participation in Germany's \"general practitioner-centred healthcare\" (GPCHC) programme, designed to strengthen general practice care, led to higher COC. Furthermore, higher COC was independently linked to decreased risks of hospitalisations, including rehospitalisations and avoidable admissions. This study aimed to investigate whether the benefits of COC for GPCHC patients persisted in 2020, the first year of the COVID-19 pandemic, compared with 2019, the year preceding the pandemic.</p><p><strong>Methods: </strong>An observational study was conducted in Germany using data from a health insurance database. The study included two patient cohorts: those enrolled in the GPCHC programme (n=1 049 910) and those not enrolled in GPCHC (n=537 759) for both 2019 and 2020. The analysis compared three measures of COC-Usual Provider Index, Herfindahl Index and Sequential Continuity Index-adjusted for patient characteristics. Longitudinal multivariable regression models were employed to evaluate differences between the cohorts and assess the impact of the COVID-19 pandemic on COC outcomes.</p><p><strong>Results: </strong>For GPCHC patients, COC in general practice was relevantly and significantly higher with respect to the three COC measures in 2019. We could observe the same advantage for GPCHC patients in 2020. Interestingly, for the SCI index, indicating the fraction of sequential encounter pairs at which the same provider is seen, we could observe that COC was even more advantageous for GPCHC patients in 2020 in comparison to 2019. Finally, we could observe that higher COC in 2019 was independently associated with decreased healthcare utilisation of the inpatient care sector in 2020.</p><p><strong>Conclusions: </strong>In a pandemic period in which healthcare is faced with new challenges, both for patients and healthcare providers, GPCHC was still associated with higher COC. The GPCHC programme and its contents are obviously better up to the requirements of the COC even in such a situation of pandemic-induced discontinuity.</p>","PeriodicalId":9052,"journal":{"name":"BMJ Open Quality","volume":"14 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient safety incident reporting systems and reporting practices in African healthcare organisations: a systematic review and meta-analysis.","authors":"Gelana Fekadu, Rachel Muir, Georgia Tobiano, Michael J Ireland, Melaku Tadege Engidaw, Andrea P Marshall","doi":"10.1136/bmjoq-2024-003202","DOIUrl":"10.1136/bmjoq-2024-003202","url":null,"abstract":"<p><strong>Background: </strong>Patient safety incident reporting and learning systems are crucial for improving the safety and quality of healthcare. However, comprehensive evidence of their availability and use in African healthcare organisations is lacking. Therefore, this review aims to synthesise the existing literature on these systems and reporting practices within African healthcare organisations.</p><p><strong>Methods: </strong>A systematic review and meta-analysis were conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Five electronic databases, including PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL) via EBSCOhost, Scopus, Web of Science and the Excerpta Medica Database (Embase), were searched to identify relevant records. Peer-reviewed articles and guidelines published in English were included in this review. Quality appraisal was performed using the Joanna Briggs Institute and Quality Assessment with Diverse Studies tool. A random effects model was used to compute the pooled prevalence using Stata V.17.0.</p><p><strong>Results: </strong>A systematic search retrieved 9279 records, of which 39 (36 articles and 3 guidelines) were included in this review. Eight patient safety incident reporting and learning systems were identified, with compliance rates ranging from low (16%) to high (87%) based on the WHO criteria. The pooled prevalence of patient safety incident reporting practices was 48% (95% CI 40% to 56%). However, the studies exhibited high heterogeneity (I²=98.75%, p<0.001).</p><p><strong>Conclusion: </strong>In African healthcare organisations, it is imperative to establish robust patient safety incident reporting and learning systems, as none of the existing systems fully meet WHO criteria. In addition, optimising the existing systems and encouraging healthcare professionals to improve reporting practices will enhance patient safety and outcomes.</p><p><strong>Prospero registration number: </strong>CRD42023455168.</p>","PeriodicalId":9052,"journal":{"name":"BMJ Open Quality","volume":"14 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11865795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concept analysis of health research translation nomenclature.","authors":"Lucylynn Lizarondo, Zoe Jordan, Ecushla Linedale, Craig Lockwood","doi":"10.1136/bmjoq-2024-002904","DOIUrl":"10.1136/bmjoq-2024-002904","url":null,"abstract":"<p><strong>Introduction: </strong>Translating health research into clinical practice is a complex process aimed at enhancing healthcare quality and patient outcomes. The terminology surrounding this process is varied and often used interchangeably, leading to minimal consensus on the activities encompassed by each term.</p><p><strong>Objectives: </strong>This study aims to examine existing taxonomies and websites for operational definitions related to health research translation, culminating in a comprehensive synopsis of terms specific to this field.</p><p><strong>Design: </strong>In 2019, a literature search was conducted using databases such as PubMed and CINAHL, along with relevant government and non-governmental organisation (NGO) websites, including grey literature. The search focused on English-language publications defining health research translation from 2000 onward and was updated in 2023. One author conducted the search, employing a mix of free-text and database-specific terms. Two authors independently evaluated the results for inclusion. Relevant data were extracted to aid in sorting and prioritising terminology based on frequency. A concept analysis approach, developed by Foley and Davis and informed by Rodgers' seven phases, was used to map the nomenclature.</p><p><strong>Results: </strong>A total of 51 papers were analysed, revealing that the most frequently used terms for health research translation were knowledge translation (KT), implementation and translational research. Both evidence-based healthcare and KT describe the process of integrating evidence into practice, positioning them as analogous. Two major domains were identified: practice and science, with practice-related language further categorised into people-focused, process-focused and outcome-focused.</p><p><strong>Conclusions: </strong>This paper presents a conceptual nomenclature map that serves as a foundation for developing a consensus-driven ontology for health research translation. The framework highlights how language can be categorised into common domains, fostering meaningful communication across diverse groups and entities.</p>","PeriodicalId":9052,"journal":{"name":"BMJ Open Quality","volume":"14 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11865793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Key clinical findings from the IMPROVE-UK quality improvement projects: an overview.","authors":"Andrew James Phillips, Rebecca Bowen, Mary Wells, Iain McNeish, Sudha Sundar","doi":"10.1136/bmjoq-2024-002902","DOIUrl":"https://doi.org/10.1136/bmjoq-2024-002902","url":null,"abstract":"<p><strong>Introduction: </strong>Survival from ovarian cancer in the UK is poor compared with international comparators. The Ovarian Cancer Audit Feasibility Pilot demonstrated variation in 1-year and 5-year survival across the UK as well as significant variation in treatment rates. In 2020, IMPROVE-UK was established as the first major programme to address inequalities in ovarian cancer management and survival across the UK, to develop a legacy of best practice sharing across the country and to establish and evaluate quality improvement projects that could drive care at scale.</p><p><strong>Methods: </strong>Following a competitive process, seven quality improvement projects were funded to address inequalities in care and identify strategies to improve and equalise survival rates for all women with ovarian cancer in the UK, to address health inequalities from geography, age or ethnicity.</p><p><strong>Results: </strong>Projects addressed the secondary care diagnostic pathway, genomic testing, prehabilitation and improving treatment-related decision-making, particularly decisions for surgery. All seven projects at least partial achieved their aims with numerous areas across all projects identified where processes could be refined and incorporated into standard care to improve outcomes of women diagnosed with ovarian cancer. Dissemination of information regarding best practice has been undertaken.</p><p><strong>Conclusion: </strong>IMPROVE-UK was the first programme of its kind addressing significant inequalities of care in women with ovarian cancer. We demonstrate systematic quality improvement projects in ovarian cancer targeting various aspects of the treatment journey. Scaling up the results of the improve UK pilots is likely to improve survival in the UK and potentially internationally.</p>","PeriodicalId":9052,"journal":{"name":"BMJ Open Quality","volume":"14 Suppl 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143498822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimising timely and safe oxygen delivery systems for enhanced patient care: a quality improvement project at Wallaga University Comprehensive Specialized Hospital, 2024.","authors":"Gedefa Bayisa, Dechassa Edessa, Kebena Limenu, Meskerem Deyasa, Ganna Gobana, Dereje Obsa, Temesgen Tilahun, Gurmessa Enkossa, Amsalu Takele, Lammii Gonfaa, Tsega Abera, Olbirat Dereje, Misganu Teshoma Regasa","doi":"10.1136/bmjoq-2024-003059","DOIUrl":"10.1136/bmjoq-2024-003059","url":null,"abstract":"<p><p>In a hospital setting, the supply and utilisation of oxygen are crucial for high-quality healthcare. This quality improvement project aimed to increase the rate of timely and safe oxygen delivery from 30% to 75% at Wallaga University Comprehensive Specialized Hospital from 1 January to 30 June 2024.Using the Plan-Do-Study-Act (PDSA) cycle, the project team identified root causes through fishbone and driver diagrams. Key interventions included staff orientation on safe handling of oxygen devices, clear job descriptions for compliance, improved handover processes between shifts, regular maintenance and inventory checks, increasing the number of oxygen cylinders, using hospital vehicles for transport and establishing a communication system with suppliers for timely requests.Results showed that the inventory of regular oxygen delivery devices improved to 76%, with equipment checks conducted 65% of the time. Emergency preparedness reached 20%, and onsite training for staff achieved 75%. Oxygen usage monitoring was nearly perfect at 99%, with delivery times reduced to 1 day for 70% of orders. A standard protocol for oxygen supply and use was established, resulting in a significant increase in timely and safe oxygen delivery from 30% to 75%.This project effectively optimised oxygen supply management, highlighting the importance of proactive management, communication and continuous monitoring in building a reliable oxygen therapy service. Improvements in inventory management and delivery efficiency were facilitated by a dedicated dashboard, standardised operating procedures and comprehensive staff training.</p>","PeriodicalId":9052,"journal":{"name":"BMJ Open Quality","volume":"14 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11865769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Holistic Integrated Care in Ovarian Cancer (HICO)-reducing inequalities due to age, frailty, poor physical and mental health.","authors":"Jonathan Frost, Claire Newton, Lucy Dumas","doi":"10.1136/bmjoq-2023-002714","DOIUrl":"https://doi.org/10.1136/bmjoq-2023-002714","url":null,"abstract":"<p><p>Older patients have disproportionally poorer survival outcomes for ovarian cancer in the UK. Half of new diagnoses occur in those aged >65 years. Older patients are more likely to have other medical comorbidities reducing their fitness to receive chemotherapy or undergo cytoreductive surgery resulting in fewer patients receiving treatment. The Holistic Integrated Care in Ovarian Cancer (HICO) programme introduced a structured holistic patient assessment with both universal and targeted interventions to improve physical function and psychological well-being to reduce inequalities due to age, frailty, physical and psychosocial problems. The aim of the project was to evaluate the feasibility and impact of the intervention in patients being considered for the treatment of ovarian cancer. During the implementation of the project, all recruited patients underwent a holistic assessment followed by prehabilitation and rehabilitation support from physiotherapists, occupational therapists, dietitians, geriatricians, nurse specialists and psychologists according to need. The HICO intervention was successfully integrated into the patient pathway in both trusts. Patients who participated in the HICO project provided positive feedback. Overall global health scores improved in 59.6% of the 57 patients who undertook at least two assessments (p=0.006). The proportion of patients who underwent platinum doublet chemotherapy in the HICO cohort was higher (76.2%) compared with a retrospective cohort (57.6%) (p=0.0189). However, no significant difference in the rate of cytoreductive surgery was shown. The proportion of patients alive at 1 year from diagnosis was higher in the HICO intervention group (88.9%) compared with the historical cohort (80.0%) despite higher stage in the HICO group. Although not statistically significant (p=0.289), these data are not yet mature and further study is ongoing. Initial data on costs of ovarian cancer care demonstrated no increase, although the data are not yet mature. This pilot project was funded through the Ovarian Cancer Action IMPROVE UK Pilot Award scheme.</p>","PeriodicalId":9052,"journal":{"name":"BMJ Open Quality","volume":"14 Suppl 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143498613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Northern Ireland ovarian cancer prehabilitation project.","authors":"Josh Courtney McMullan, Davinia Lee, Lisa Ranaghan, Nicola Gowan, Lisa McWilliams, Bernie McGreevy, Danielle O'Hagan, Brenda Nugent, Stephen Dobbs","doi":"10.1136/bmjoq-2024-002851","DOIUrl":"https://doi.org/10.1136/bmjoq-2024-002851","url":null,"abstract":"<p><p>Patients with ovarian cancer are often diagnosed late, in advanced stages (stages III-IV) and are often deconditioned due to disease burden. Frailty is reported in up to 60% of gynaecological oncology patients and many report malnutrition, anxiety and depression. As surgery is the mainstay of treatment for ovarian cancer, with maximum surgical effort being a priority, patients are at increased risk of perioperative morbidity and mortality.Multimodal prehabilitation aims to improve the functional capacity of surgical patients. Prehabilitation commonly includes physical, nutritional, medical optimisation, smoking cessation and emotional well-being interventions. Many surgical specialties have well established evidence for the use of prehabilitation showing a reduction in length of stay and perioperative complications. There is, however, limited evidence for the use of prehabilitation in the surgically vulnerable group of patients with advanced ovarian cancer.This project aimed to introduce a multimodal prehabilitation pathway for patients with advanced ovarian cancer. All patients with advanced ovarian cancer were included, regardless of the treatment modality decided at the regional gynaecological oncology multidisciplinary team meeting. The pathway included exercise, nutritional and psychological interventions. The outcome measures included the Rockwood Frailty Score, 6 min Walk Test (6MWT), 30 s Chair to Stand test, grip strength and Eastern Cooperative Oncology Group performance status as a measure of functional capacity. Nutritional intervention outcomes included the Malnutrition Universal Screening Tool (MUST) score, Body mass index and mid-arm circumference. The psychological intervention outcomes included a holistic needs assessment, the distress thermometer and EQ-5D-5L quality of life status.Of the 75 patients enrolled, 45 (60%) completed the project. In patients who completed the project improved 6MWT and 30-CST was observed in 67% and 44%, respectively, while 67% of patients with moderate to extreme anxiety/depression scores reported lowering from baseline level and 71% of patients with medium to high-risk MUST scores baseline weight was maintained or increased.</p>","PeriodicalId":9052,"journal":{"name":"BMJ Open Quality","volume":"14 Suppl 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143498902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scottish ovarian cancer forum.","authors":"Mary Cairns, Nidal Ghaoui Dit Ebef","doi":"10.1136/bmjoq-2023-002715","DOIUrl":"https://doi.org/10.1136/bmjoq-2023-002715","url":null,"abstract":"<p><p>The project was to set up a multicentre collaborative real-time multidisciplinary review of women with advanced ovarian cancer (stages 3/4) being considered for surgery (upfront or interval). The forum met weekly via TEAMS with input from all relevant disciplines from the two cancer networks: North Cancer Alliance and South East Scotland Cancer Network. This included radiology, medical oncology, gynaecological oncology, clinical nurse specialists, colorectal and hepato-pancreatico-biliary surgeons. It was an educational forum to review radiology and assess the feasibility of surgical resection. The aim was to stratify and standardise surgical decision-making and increase surgical rates.</p>","PeriodicalId":9052,"journal":{"name":"BMJ Open Quality","volume":"14 Suppl 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143498912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promoting equitable genetic testing in ovarian cancer: the demonstration of improvement for molecular ovarian cancer testing (DEMO) project.","authors":"Elaine Yl Leung, Ionut Gabriel Funingana, Lisa Bird, Marie-Lyne Alcaraz, Anuji Evans, Anna Considine, Susan Freeman, Mercedes Jimenez-Linan, Catherine Spencer, Kiran Phanasan, Julie Winning, Joo Ern Ang, Christine Parkinson, Kai Ren Ong, Samantha Butler, Oliver Ridgway, Ian Charles, Rachel Pannell, Parveen Abedin, William Boyle, Jamie Emery, Jayne Salter-Scott, Sarah Williams, Raji Ganesan, Sudha Sundar, Janos Balega, James D Brenton","doi":"10.1136/bmjoq-2023-002720","DOIUrl":"10.1136/bmjoq-2023-002720","url":null,"abstract":"<p><p>Parallel genetic testing (testing for both tumour and germline gene changes) after the diagnosis of ovarian cancer should be considered the standard of care and is crucial to support treatment decisions. The demonstration of improvement for molecular ovarian cancer testing (DEMO) project aimed to develop patient-focused tools to promote equitable genetic care in diverse communities with high proportions of patients with limited English proficiency and biopsy guidelines to address the variations in specimen quality in different geographical regions in the UK. Our three work packages (WP) aimed to promote awareness by addressing the information gaps in different community groups (WP1), develop infrastructure to evaluate the different tissue collection pathways in different regions (WP2) and support continuing professional development (CPD) to encourage best practices with the involvement of patients (WP3). Our output included a multimedia multilanguage information package with paired National Health Service-branded written materials to support genetic testing after ovarian cancer diagnosis (https://ovarian.org.uk/demo-uk/), a scalable database to enable a multisite audit of parallel genetic testing pathways and a collection of CPD events that had patient involvement as an essential component. In addition, we have collaborated with patient and community groups to contribute to a national consensus guidance on genetic testing in ovarian cancer. Our co-production work has been recognised by local and regional awards as an exemplar for patient and public involvement (PPI). This has supported the start of a legacy co-production group in gynaeoncology (https://www.dhlnetwork.com/gohildas) to address the critical unmet need for sustainable and equity-oriented PPI to advocate for underserved communities. The DEMO project has contributed to raising awareness of the importance of equitable genetic care in ovarian cancer. We will continue to build on this groundwork to support future quality improvement projects and research, with the ultimate goal of improving the outcomes of patients with ovarian cancer.</p>","PeriodicalId":9052,"journal":{"name":"BMJ Open Quality","volume":"14 Suppl 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11865723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143498908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}